Jonathan Sprent

Q: What Schools Are Affiliated With Jonathan Sprent

Jonathan Sprent is affiliated with the following schools: Pohang University of Science and Technology, University of New South Wales, University of Sydney, University of Melbourne, University of Pennsylvania

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Jonathan Sprent

Biology

#2927

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#4559

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Immunology

#118

World Rank

#125

Historical Rank

biology Degrees

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Biology

Jonathan Sprent's Degrees

PhD Immunology University of Melbourne

Why Is Jonathan Sprent Influential?

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According to Wikipedia, Professor Jonathan Sprent, , is an Australian immunologist. His research has focused on the formation and activation of T cell leukocytes, and methods to overcome T cell-mediated rejection of transplanted tissue.

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Jonathan Sprent's Published Works

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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. (1998) (1394)
The role of interleukin-2 during homeostasis and activation of the immune system (2012) (1281)
Induction of Bystander T Cell Proliferation by Viruses and Type I Interferon in Vivo (1996) (1191)
T-cell apoptosis detected in situ during positive and negative selection in the thymus (1994) (1168)
Homeostasis of naive and memory T cells. (2008) (1167)
T cell memory. (2003) (1065)
IL-7 is critical for homeostatic proliferation and survival of naïve T cells (2001) (1030)
Turnover of naive- and memory-phenotype T cells (1994) (1022)
Type I interferons act directly on CD8 T cells to allow clonal expansion and memory formation in response to viral infection (2005) (981)
Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity (1990) (947)
Interleukin (IL)-15 and IL-7 Jointly Regulate Homeostatic Proliferation of Memory Phenotype CD8+ Cells but Are Not Required for Memory Phenotype CD4+ Cells (2002) (896)
The peptide ligands mediating positive selection in the thymus control T cell survival and homeostatic proliferation in the periphery. (1999) (859)
Selective Stimulation of T Cell Subsets with Antibody-Cytokine Immune Complexes (2006) (846)
A fundamental role for interleukin-21 in the generation of T follicular helper cells. (2008) (717)
A monoclonal antibody discriminating between subsets of T and B cells. (1981) (548)
Lethal graft-versus-host disease after bone marrow transplantation across minor histocompatibility barriers in mice. Prevention by removing mature T cells from marrow (1978) (528)
In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression (2009) (509)
TCR-Mediated internalization of peptide-MHC complexes acquired by T cells. (1999) (478)
T Cell Selection in the Thymus (1988) (472)
CELL-TO-CELL INTERACTION IN THE IMMUNE RESPONSE (1968) (454)
Lymphocyte life-span and memory. (1994) (451)
Normal T cell homeostasis: the conversion of naive cells into memory-phenotype cells (2011) (451)
Type I Interferon-mediated Stimulation of T Cells by CpG DNA (1998) (406)
Interleukin 15 Controls both Proliferation and Survival of a Subset of Memory-Phenotype CD8+ T Cells (2002) (400)
Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}. (2006) (395)
A RECEPTOR FOR ANTIBODY ON B LYMPHOCYTES (1972) (390)
T Cell Stimulation In Vivo by Lipopolysaccharide (LPS) (1997) (359)
Overexpression of Interleukin (IL)-7 Leads to IL-15–independent Generation of Memory Phenotype CD8+ T Cells (2002) (328)
Homeostasis of memory T cells (2006) (320)
Circulating T and B lymphocytes of the mouse. I. Migratory properties. (1973) (316)
T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes. (1987) (311)
A defect in central tolerance in NOD mice (2001) (295)
Abnormal differentiation of thymocytes in mice treated with cyclosporin A (1988) (288)
T and B memory cells (1994) (284)
Reentry of T cells to the adult thymus is restricted to activated T cells (1991) (276)
Negative Selection in the Thymus Includes Semimature T Cells (1997) (262)
Identity of cells that imprint H–2-restricted T-cell specificity in the thymus (1986) (261)
The thymus and negative selection (2002) (260)
T Cells Can Use Either T Cell Receptor or Cd28 Receptors to Absorb and Internalize Cell Surface Molecules Derived from Antigen-Presenting Cells (2000) (258)
Antiviral CD4+ memory T cells are IL-15 dependent (2007) (257)
Homeostatic proliferation and survival of naïve and memory T cells (2009) (252)
Circulating T and B lymphocytes of the mouse. II. Lifespan. (1973) (248)
Interaction between lymphocytes in immune responses. (1971) (246)
Properties of purified T cell subsets. II. In vivo responses to class I vs. class II H-2 differences (1986) (238)
Antigen-induced selective recruitment of circulating lymphocytes. (1971) (231)
Intrathymic and extrathymic clonal deletion of T cells. (1995) (229)
T cell subsets and graft-versus-host disease. (1987) (224)
IL-7 regulates basal homeostatic proliferation of antiviral CD4+T cell memory. (2004) (221)
T Cell Death and Memory (2001) (221)
Regulation of mature T cell homeostasis. (2005) (219)
Homeostatic T Cell Proliferation: How Far Can T Cells Be Activated to Self-Ligands? (2000) (214)
Function and specificity of T cell subsets in the mouse. (1987) (197)
Cytokines and T-cell homeostasis. (2003) (194)
Requirements for Peptide-induced T Cell Receptor Downregulation on Naive CD8+ T Cells (1997) (189)
QUANTITATIVE FEATURES OF A SANDWICH RADIOIMMUNOLABELING TECHNIQUE FOR LYMPHOCYTE SURFACE RECEPTORS (1972) (186)
Mature murine B and T cells transferred to SCID mice can survive indefinitely and many maintain a virgin phenotype (1991) (185)
IL-2/anti-IL-2 antibody complexes show strong biological activity by avoiding interaction with IL-2 receptor α subunit CD25 (2010) (183)
A Role for Fas in Negative Selection of Thymocytes In Vivo (1998) (178)
Variable capacity of L3T4+ T cells to cause lethal graft-versus-host disease across minor histocompatibility barriers in mice (1987) (177)
Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. II. Evidence for restrictions affecting helper cell induction and T-B collaboration, both mapping to the K-end of the H-2 complex (1978) (176)
Generation and maintenance of memory CD4(+) T Cells. (2001) (174)
DNA as an Adjuvant: Capacity of Insect DNA and Synthetic Oligodeoxynucleotides to Augment T Cell Responses to Specific Antigen (1998) (173)
Direct stimulation of naïve T cells by membrane vesicles from antigen-presenting cells: Distinct roles for CD54 and B7 molecules (2003) (170)
Thymic selection by a single MHC/peptide ligand produces a semidiverse repertoire of CD4+ T cells. (1997) (166)
Regulatory T cells expressing granzyme B play a critical role in controlling lung inflammation during acute viral infection (2012) (159)
CELL-TO-CELL INTERACTION IN THE IMMUNE RESPONSE (1968) (156)
Generation and maintenance of memory T cells. (2001) (156)
Lifespans of naive, memory and effector lymphocytes. (1993) (149)
Several Different Cell Surface Molecules Control Negative Selection of Medullary Thymocytes (1999) (148)
Cytokines and T cell homeostasis. (2007) (147)
Role of H‐2 Gene Products in the Function of T Helper Cells from Normal and Chimeric Mice in Vivo 1 (1978) (145)
Collaboration of histoincompatible T and B lymphocytes using cells from tetraparental bone marrow chimeras (1975) (143)
Transfected Drosophila cells as a probe for defining the minimal requirements for stimulating unprimed CD8+ T cells. (1996) (142)
Association of immunity and tolerance to host H-2 determinants in irradiated F1 hybrid mice reconstituted with bone marrow cells from one parental strain (1975) (141)
Fate of H2-activated T lymphocytes in syngeneic hosts. I. Fate in lymphoid tissues and intestines traced with 3H-thymidine, 125I-deoxyuridine and 51chromium. (1976) (140)
T cell reactivity to MHC molecules: immunity versus tolerance. (1990) (139)
Properties of purified T cell subsets. I. In vitro responses to class I vs. class II H-2 alloantigens (1985) (139)
Growth of epithelial cells in the thymic medulla is under the control of mature T cells (1992) (138)
CD40 Ligand-Mediated Interactions Are Involved in the Generation of Memory CD8+ Cytotoxic T Lymphocytes (CTL) but Are Not Required for the Maintenance of CTL Memory following Virus Infection (1998) (138)
IL-7/Anti-IL-7 mAb Complexes Restore T Cell Development and Induce Homeostatic T Cell Expansion without Lymphopenia1 (2008) (137)
A novel class II MHC molecule with unusual tissue distribution (1991) (136)
Mitogenicity of DNA from different organisms for murine B cells. (1997) (136)
B7 expression on thymic medullary epithelium correlates with epithelium-mediated deletion of V beta 5+ thymocytes. (1994) (132)
Homeostatic T Cell Proliferation (2000) (132)
An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2 (2007) (131)
Potential use of IL-2/anti-IL-2 antibody immune complexes for the treatment of cancer and autoimmune disease (2006) (129)
Two subsets of epithelial cells in the thymic medulla (1992) (129)
Upregulation of surface markers on dying thymocytes (1995) (128)
Features of T cells causing H-2-restricted lethal graft-vs.-host disease across minor histocompatibility barriers (1982) (127)
Stimulation of naive and memory T cells by cytokines (1999) (125)
T cell receptor-dependent regulation of lipid rafts controls naive CD8+ T cell homeostasis. (2010) (123)
Strong TCR ligation without costimulation causes rapid onset of Fas-dependent apoptosis of naive murine CD4+ T cells. (1999) (121)
Surface markers of T cells causing lethal graft-vs-host disease to class I vs class II H-2 differences. (1985) (121)
Cell surface polysaccharides of Bifidobacterium bifidum induce the generation of Foxp3+ regulatory T cells (2018) (119)
Tolerance to histocompatibility determinants in tetraparental bone marrow chimeras (1975) (118)
An IFN-γ-Dependent Pathway Controls Stimulation of Memory Phenotype CD8+ T Cell Turnover In Vivo by IL-12, IL-18, and IFN-γ1 (2001) (115)
Induction of neonatal tolerance to Mlsa antigens by CD8+ T cells. (1990) (109)
Lifespan of γ/δ T Cells (1998) (108)
Influence of antigen dose and costimulation on the primary response of CD8+ T cells in vitro (1996) (106)
CELL-TO-CELL INTERACTION IN THE IMMUNE RESPONSE (1974) (106)
Role of T cell subsets in lethal graft-versus-host disease (GVHD) directed to class I versus class II H-2 differences. I. L3T4+ cells can either augment or retard GVHD elicited by Lyt-2+ cells in class I different hosts (1988) (105)
ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes (2011) (104)
Strong T cell tolerance in parent----F1 bone marrow chimeras prepared with supralethal irradiation. Evidence for clonal deletion and anergy (1990) (104)
Radiosensitivity of T and B lymphocytes. II. Effect of irradiation on response of T cells to alloantigens (1974) (99)
B cell-derived immunoglobulin on activated mouse T lymphocytes (1974) (99)
Expression of M locus differences by B cells but not T cells (1974) (98)
Differing roles for B7 and intercellular adhesion molecule-1 in negative selection of thymocytes (1996) (97)
Homeostatic maintenance of T cells and natural killer cells (2012) (96)
Radiosensitivity of T and B lymphocytes. I. Effect of irradiation on cell migration (1974) (95)
Regulation of naïve and memory T-cell homeostasis. (2002) (94)
Thymic selection and cell division (1995) (94)
Aging Leads to Disturbed Homeostasis of Memory Phenotype CD8+ Cells (2002) (94)
Lethal GVHD Across Minor Histocompatibility Barriers: Nature of the Effector Cells and Role of the H‐2 Complex (1983) (93)
Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis (1992) (93)
Receptor for antibody-antigen complexes used to separate T cells from B cells. (1972) (93)
Restricted helper function of F1 leads to parent bone marrow chimeras controlled by K-end of H-2 complex (1978) (92)
Lifespan of lymphocytes (1995) (91)
Dual function of Drosophila cells as APCs for naive CD8+ T cells: implications for tumor immunotherapy. (1996) (91)
Factors controlling the turnover of T memory cells (1997) (90)
Interaction of thymus lymphocytes with histoincompatible cells. II. Recirculating lymphocytes derived from antigen-activated thymus cells. (1972) (90)
Restricted tissue distribution of Mlsa determinants. Stimulation of Mlsa-reactive T cells by B cells but not by dendritic cells or macrophages (1989) (89)
Helper function of T cells depleted of alloantigen-reactive lymphocytes by filtration through irradiated F1 hybrid recipients. I. Failure to collaborate with allogeneic B cells in a secondary response to sheep erythrocytes measured in vivo (1976) (89)
Simultaneous deletion of MyD88 and Trif delays major histocompatibility and minor antigen mismatch allograft rejection (2006) (88)
Activation of thymus cells by histocompatibility antigens. (1971) (88)
The thymus and central tolerance. (1996) (86)
Functions of Purified L3T4+ and Lyt‐2+ Cells in vitro and in vivo (1986) (86)
The generation of killer cells to trinitrophenyl-modified allogeneic targets by lymphocyte populations negatively selected to strong alloantigens (1977) (82)
SURFACE IMMUNOGLOBULINS ON THYMUS AND THYMUS-DERIVED LYMPHOID CELLS (1971) (82)
Tolerogenicity of thymic epithelium (1990) (81)
Viruses and T Cell Turnover: Evidence for Bystander Proliferation (1996) (81)
Regulation of naive T cell function by the NF-κB2 pathway (2006) (79)
Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. I. Failure to collaborate with B cells of the opposite parental strain not associated with active suppression (1978) (78)
Five types of lymphocytes (lg− θ−, lg− θ+ weak, lg− θ+strong, lg+ θ− and lg+ θ+) characterized by double immunofluorescence and electrophoretic mobility Organ distribution in normal and nude mice (1975) (77)
Resting and activated T cells display different requirements for CD8 molecules (1994) (77)
Interaction of thymus lymphocytes with histoincompatible cells. 3. Immunological characteristics of recirculating lymphocytes derived from activated thymus cells. (1972) (76)
Life span of naive and memory t cells (1995) (75)
Interleukin-21 Is Critically Required in Autoimmune and Allogeneic Responses to Islet Tissue in Murine Models (2011) (75)
Effects of blocking helper T cell induction in vivo with anti-Ia antibodies. Possible role of I-A/E hybrid molecules as restriction elements (1980) (74)
Interaction of thymus lymphocytes with histoincompatible cells. I. Quantitation of the proliferative response of thymus cells. (1972) (74)
IL-21 restricts T follicular regulatory T cell proliferation through Bcl-6 mediated inhibition of responsiveness to IL-2 (2017) (74)
Antigen-presenting cells for unprimed T cells. (1989) (72)
Fc-receptors, Ia-antigens, and immunoglobulin on normal and activated mouse T lymphocytes (1975) (71)
Stimulation of mature unprimed CD8+ T cells by semiprofessional antigen- presenting cells in vivo (1992) (71)
IL-17-producing NKT cells depend exclusively on IL-7 for homeostasis and survival (2014) (70)
Antigen-Presenting Cells: Professionals and amateurs (1995) (69)
Dual Nature of Type I Interferons in SARS-CoV-2-Induced Inflammation (2021) (69)
Thymus-grafted SCID mice show transient thymopoiesis and limited depletion of V beta 11+ T cells (1992) (69)
Antigen-binding specificity of isolated cell-surface immunoglobulin from thymus cells activated to histocompatibility antigens. (1972) (68)
Thoracic duct lymphocytes from nude mice: Migratory properties and life‐span (1972) (67)
Profound atrophy of the bone marrow reflecting major histocompatibility complex class II-restricted destruction of stem cells by CD4+ cells (1994) (67)
Antigen‐presenting Cells for CD8+ T Cells (1990) (67)
Exclusion of circulating T cells from the thymus does not apply in the neonatal period (1993) (66)
Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus (2009) (66)
A major histocompatibility complex class I–dependent subset of memory phenotype CD8+ cells (2006) (65)
Physiology of B cells in mice with X-linked immunodeficiency (xid). III. Disappearance of xid B cells in double bone marrow chimeras (1984) (65)
Thymic selection by a single MHC/peptide ligand: autoreactive T cells are low-affinity cells. (1999) (64)
Direct stimulation of T cells by membrane vesicles from antigen-presenting cells. (2006) (63)
Central tolerance of T cells. (1995) (63)
Role of the Actin Cytoskeleton in T Cell Absorption and Internalization of Ligands from APC1 (2001) (63)
T-cell proliferation in vivo and the role of cytokines. (2000) (62)
Specific adsorption of IgM antibody onto H-2-activated mouse T lymphocytes (1976) (62)
T cell homeostasis (2008) (62)
Thymus-derived cells in mouse thoracic duct lymph. (1971) (61)
Absence of H-2 restriction in primary and secondary mixed-lymphocyte reactions to strong M1s determinants (1980) (61)
Transgenic HLA-DRα faithfully reconstitutes IE-controlled immune functions and induces cross-tolerance to Eα in Eα 0 mutant mice (1989) (60)
Capacity of small B cell‐enriched populations to stimulate mixed lymphocyte reactions: marked differences between irradiated vs. mitomycin C‐treated stimulators (1985) (60)
CD4+ cell turnover (1995) (60)
T cell clones with dual specificity for M1s and various major histocompatibility complex determinants (1981) (60)
Direct stimulation of naïve T cells by antigen-presenting cell vesicles. (2005) (59)
T-cell turnover in vivo and the role of cytokines. (1999) (58)
Negative selection of T cells causing lethal graft-versus-host disease across minor histocompatibility barriers. Role of the H-2 complex (1980) (57)
The induction of in vivo proliferation of long-lived CD44hi CD8+ T cells after the injection of tumor cells expressing IFN-alpha1 into syngeneic mice. (1998) (56)
Effect of recent antigen priming on adoptive immune responses. III. Antigen-induced selective recruitment of subsets of recirculating lymphocytes reactive to H-2 determinants (1976) (56)
The role of interleukin-2 in memory CD8 cell differentiation. (2010) (56)
Stimulation of memory T cells by cytokines. (2000) (56)
Expansion/deletion of mature T cells exposed to endogenous superantigens in vivo. (1994) (55)
T Cell Function in Bone Marrow Chimeras; Absence of Host‐Reactive T Cells and Cooperation of Helper T Cells across Allogeneic Barriers (1976) (55)
IL-2/IL-2Ab complexes induce regulatory T cell expansion and protect against proteinuric CKD. (2012) (55)
Turnover of memory-phenotype CD8+ T cells. (2003) (54)
The Lymphopenic Environment of CD132 (Common γ-Chain)-Deficient Hosts Elicits Rapid Homeostatic Proliferation of Naive T Cells via IL-151 (2008) (53)
COVID-19 vaccine side effects: The positives about feeling bad (2021) (53)
EFFECT OF RECENT ANTIGEN PRIMING ON ADOPTIVE IMMUNE RESPONSES (1973) (53)
The thymus and central tolerance. (2000) (51)
Thymus-derived cells as killer cells in cell-mediated immunity. (1971) (51)
Regulation of naive T cell function by the NF-kappaB2 pathway. (2006) (51)
Potent antitumour activity of interleukin-2-Fc fusion proteins requires Fc-mediated depletion of regulatory T-cells (2017) (51)
Role of the H-2 complex in induction of T helper cells in vivo. I. Antigen-specific selection of donor T cells to sheep erythrocytes in irradiated mice dependent upon sharing of H-2 determinants between donor and host (1978) (50)
Fate of H2-activated T lymphocytes in syngeneic hosts. II. Residence in recirculating lymphocyte pool and capacity to migrate to allografts. (1976) (49)
Split tolerance in spleen chimeras. (1995) (49)
Capacity of purified Lyt-2+ T cells to mount primary proliferative and cytotoxic responses to Ia− tumour cells (1986) (49)
Fate of H2-activated T lymphocytes in syngeneic hosts. III. Differentiation into long-lived recirculating memory cells. (1976) (49)
Role of T cell subsets in lethal graft-versus-host disease (GVHD) directed to class I versus class II H-2 differences. II. Protective effects of L3T4+ cells in anti-class II GVHD. (1990) (48)
The role of host T cell subsets in bone marrow rejection directed to isolated major histocompatibility complex class I versus class II differences of bm1 and bm12 mutant mice. (1994) (48)
Requirements for stimulating naive CD8+ T cells via signal 1 alone. (1998) (47)
Swapping Molecules During Cell-Cell Interactions (2005) (47)
Unique Features of Naive CD8+ T Cell Activation by IL-2 (2013) (46)
Characterization of target injury of murine acute graft-versus-host disease directed to multiple minor histocompatibility antigens elicited by either CD4+ or CD8+ effector cells. (1991) (46)
Response of mature unprimed CD8+ T cells to Mlsa determinants (1990) (45)
Selection of cytotoxic T-cell precursors specific for minor histocompatibility determinants. I. Negative selection across H-2 barriers induced with disrupted cells but not with glutaraldehyde- treated cells: evidence for antigen processing (1980) (45)
Capacity of unprimed CD4+ and CD8+ T cells expressing V beta 11 receptors to respond to I-E alloantigens in vivo (1989) (44)
Receptors for immunoglobulin on B lymphocytes and cells of a cultured plasma cell tumor. (1972) (44)
T cell specificity in twice-irradiated F1----parent bone marrow chimeras: failure to detect a role for immigrant marrow-derived cells in imprinting intrathymic H-2 restriction. (1986) (44)
T cell contact with Ia antigens on nonhemopoietic cells in vivo can lead to immunity rather than tolerance (1991) (43)
The thymus and central tolerance. (2001) (42)
The majority of murine γδ T cells at the maternal–fetal interface in pregnancy produce IL‐17 (2016) (42)
EFFECT OF RECENT ANTIGEN PRIMING ON ADOPTIVE IMMUNE RESPONSES (1974) (41)
Bone marrow-derived cells fail to induce positive selection in thymus reaggregation cultures (1996) (41)
An IFN-gamma-dependent pathway controls stimulation of memory phenotype CD8+ T cell turnover in vivo by IL-12, IL-18, and IFN-gamma. (2001) (40)
Lifespan of gamma/delta T cells. (1998) (39)
Physiology of B cells in mice with X-linked immunodeficiency. II. Influence of the thymus and mature T cells on B cell differentiation (1984) (39)
Bystander stimulation of T cells in vivo by cytokines. (1998) (39)
Differential Responsiveness of Innate-like IL-17– and IFN-γ–Producing γδ T Cells to Homeostatic Cytokines (2016) (38)
Intrathymic and Extrathymic Tolerance in Bone Marrow Chimeras (1993) (38)
B lymphocytes as stimulators of a mixed lymphocyte reaction. (1973) (36)
Probing the activation requirements for naive CD8+ T cells with Drosophila cell transfectants as antigen presenting cells (1998) (35)
HIV results in the frame. CD4+ cell turnover. (1995) (35)
Long-term xenogeneic chimeras. Full differentiation of rat T and B cells in SCID mice. (1991) (35)
Effect of recent antigen priming on adoptive immune responses. IV. Antigen-induced selective recruitment of recirculating lymphocytes to the spleen demonstrable with a microculture system (1976) (32)
CD45-mediated control of TCR tuning in naïve and memory CD8+ T cells (2016) (31)
Downregulation of T cell responses by antibodies to the T cell receptor (1987) (31)
Tolerance of CD8+ T cells developing in parent-->F1 chimeras prepared with supralethal irradiation: step-wise induction of tolerance in the intrathymic and extrathymic environments (1993) (31)
Graft-Versus-Host Disease in Experimental Allogeneic Bone Marrow Transplantation (1991) (31)
Immunoglobulin on activated T cells detected by indirect immunofluorescence. (1974) (31)
Exogenous control of I-A expression in fetal thymus explants. (1986) (30)
Treg-mediated prolonged survival of skin allografts without immunosuppression (2019) (30)
Selectively expanding subsets of T cells in mice by injection of interleukin-2/antibody complexes: implications for transplantation tolerance. (2012) (30)
Emerging cellular networks for regulation of T follicular helper cells. (2012) (29)
Knowing one's self: central tolerance revisited (2003) (29)
Food antigens drive spontaneous IgE elevation in the absence of commensal microbiota (2019) (28)
Re‐entry of mature T cells to the thymus: an epiphenomenon? (2009) (28)
Immunoglobulin turnover in B lymphocyte subpopulations (1975) (28)
Lethal graft-versus-host disease across minor histocompatibility barriers in mice. (1983) (28)
Selective cytotoxicity of anti-kappa serum for B lymphocytes. (1972) (27)
T cell receptors for responses to Mls determinants and allo-H-2 determinants appear to be encoded on different chromosomes (1985) (27)
Ex vivo-expanded DCs induce donor-specific central and peripheral tolerance and prolong the acceptance of donor skin grafts. (2011) (27)
Antigen-induced selective sequestration of T lymphocytes: role of the major histocompatibility complex. (1980) (27)
Evidence that strong Mls determinants are nonpolymorphic. (1981) (26)
Interaction of thymus lymphocytes with histoincompatible cells. IV. Mixed lymphocyte reactions of activated thymus lymphocytes. (1974) (25)
Calcineurin-dependent negative regulation of CD94/NKG2A expression on naive CD8+ T cells. (2011) (25)
Role of type I interferons in T cell activation induced by CpG DNA. (2000) (25)
TCR tuning of T cell subsets (2018) (25)
T-helper function of parent leads to F1 chimeras. Presence of a separate T-cell subgroup able to stimulate allogeneic B cells but not syngeneic B cells (1979) (25)
Presidential address to the American Association of Immunologists. Stimulating naive T cells. (1999) (24)
Physiology of B cells in mice with X-linked immunodeficiency. I. Size, migratory properties, and turnover of the B cell pool. (1985) (24)
T‐Cell Responses and Tolerance to Mlsa Determinants (1989) (23)
Factors Controlling the Reactivity of Immature and Mature T Cells to Mlsa Antigens in vivo (1993) (23)
Breakdown in Repression of IFN-γ mRNA Leads to Accumulation of Self-Reactive Effector CD8+ T Cells (2012) (22)
ATP11c is critical for phosphatidylserine internalization and B lymphocyte differentiation (2011) (22)
Measurement of T and B Cell Turnover with Bromodeoxyuridine (1996) (22)
Rat T cell responses to superantigens. II. Allelic differences in V beta 8.2 and V beta 8.5 beta chains determine responsiveness to staphylococcal enterotoxin B and mouse mammary tumor virus-encoded products (1994) (22)
Inhibition of T cell activation in vivo with mixtures of monoclonal antibodies specific for I-A and I-A/E molecules (1981) (21)
An unusual class II molecule. (1992) (21)
CELL-TO-CELL INTERACTION IN THE IMMUNE RESPONSE (1972) (20)
T Cells with Multiple Specificities (1986) (20)
A Bacterial Metabolite, Compound K, Induces Programmed Necrosis in MCF-7 Cells via GSK3β. (2015) (20)
IL-21 Contributes to Fatal Inflammatory Disease in the Absence of Foxp3+ T Regulatory Cells (2014) (20)
Anti-viral immunity: Spotting virus-specific T cells (1998) (20)
Factors influencing the fate of T cells responding to Mls antigens. (1992) (20)
T cell lines with dual specificity for strong Mls and H-2 determinants. (1980) (20)
Interleukin 7, maestro of the immune system. (2012) (19)
T cell tolerance after bone marrow transplantation in mice. (1992) (19)
The Thymus and T‐Cell Tolerance a (1993) (19)
IL-2 Shapes the Survival and Plasticity of IL-17–Producing γδ T Cells (2017) (19)
T Memory Cells: Quality not Quantity (2002) (18)
Role of the H-2 complex in induction of T helper cells in vivo. II Negative selection of discrete subgroups of T cells restricted by I-A and I-A/E determinants (1981) (18)
Rat T cell response to superantigens. I. V beta-restricted clonal deletion of rat T cells differentiating in rat-->mouse chimeras (1994) (18)
Prolonged survival in vivo of unprimed B cells responsive to a T- independent antigen (1985) (18)
T cell subsets controlling graft-v-host disease in mice. (1987) (18)
Immunological Memory (1990) (17)
Lyb-8.2: A new B cell antigen defined and characterized with a monoclonal antibody (2004) (17)
Cytokines and memory-phenotype CD8+ cells. (2002) (17)
High levels of soluble CD25 in COVID‐19 severity suggest a divergence between anti‐viral and pro‐inflammatory T‐cell responses (2021) (17)
Systemic Human T Cell Developmental Processes in Humanized Mice Cotransplanted With Human Fetal Thymus/Liver Tissue and Hematopoietic Stem Cells (2012) (17)
T‐cell survival and the role of cytokines (2001) (16)
A monoclonal antibody detecting an Ia specificity mapping in the I-A or I-E subregion (2004) (16)
Features of cells controlling H-2-restricted presentation of antigen to T helper cells in vivo. (1980) (16)
On the possibility of multiple t-cell receptors. (1977) (16)
Multiple effects of immunostimulatory DNA on T cells and the role of type I interferons (2009) (16)
Unregulated antigen-presenting cell activation by T cells breaks self tolerance (2018) (15)
Induction of intestinal graft-versus-host reactions across mutant major histocompatibility antigens by T lymphocyte subsets in mice. (1989) (15)
H-2 restriction of T cells causing lethal graft-versus-host disease across minor histocompatibility barriers in mice. (1981) (15)
Two subgroups of T helper cells in F1 hybrid mice revealed by negative selection to heterologous erythrocytes in vivo. (1978) (14)
The thymus and negative selection (2000) (14)
Treg Therapies Revisited: Tolerance Beyond Deletion (2021) (14)
Self/non‐self discrimination and the problem of keeping T cells alive (2008) (14)
Capacity of purified unprimed Lyt-2+ cells to reject Ia- H-2-different tumor cells in the Winn assay. (1988) (14)
T Cell Tolerance and the Thymus a (1998) (14)
GM-CSF Culture Revisited: Preparation of Bulk Populations of Highly Pure Dendritic Cells from Mouse Bone Marrow (2018) (14)
Proving Negative Selection in the Thymus (2005) (13)
Cytosolic Recognition of RNA Drives the Immune Response to Heterologous Erythrocytes. (2017) (13)
T cell tolerance and self/nonself discrimination. (1993) (13)
Thymic emigration - a reply (1995) (12)
Immunogenetics of graft-versus-host reactions to minor histocompatibility antigens. (1981) (12)
Lymphoid function in F1 leads to parent chimeras: lack of evidence for adaptive differentiation of B cells or antigen-presenting cells (1979) (12)
Phenotypic and Functional Changes of Peripheral Ly6C+ T Regulatory Cells Driven by Conventional Effector T Cells (2018) (12)
Staying alive – naïve CD4+ T cell homeostasis (2007) (10)
Homeostasis of Naive and Memory T Lymphocytes. (2021) (10)
Is IL-7 from dendritic cells essential for the homeostasis of CD4+ T cells? (2010) (10)
Negative selection in vivo reveals expression of strong Mls determinants in mice with X-linked immunodeficiency (1984) (10)
TGF-β puts the brakes on homeostatic proliferation (2012) (10)
New insights on T-cell self-tolerance. (2019) (10)
CD70–CD27 ligation between neural stem cells and CD4+ T cells induces Fas–FasL-mediated T-cell death (2013) (10)
Antigen-presenting cells for Lyt-2+ cells. I. Stimulation of unprimed Lyt-2+ cells by H-2 different Thy-1-Ia- cells prepared from spleen and bone marrow. (1988) (10)
NF‐κB2 Controls the Migratory Activity of Memory T Cells by Regulating Expression of CXCR4 in a Mouse Model of Sjögren's Syndrome (2017) (10)
Writer's block: preventing m6A mRNA methylation promotes T cell naivety (2017) (9)
TCB2, a new anti-human interleukin-2 antibody, facilitates heterodimeric IL-2 receptor signaling and improves anti-tumor immunity (2019) (9)
Fate of T and B cells transferred to SCID mice. (1994) (9)
Lifespan of g / d T Cells By (1998) (9)
Activation of T lymphocytes to M locus determinants in vivo.. I. Quantitation of T cell proliferation and migration into thoracic duct lymph (1976) (9)
T-cell selection in the thymus. (1988) (9)
Surface immunoglobulin on H-2-activated T lymphocytes. (1973) (8)
Analysis of T hybridomas prepared from a T cell clone with three specificities. Recognition of self + X and allo-H-2 determinants segregates from recognition of Mlsa determinants. (1988) (8)
Role of the H-2 complex in induction of T helper cells in vivo. III. Contribution of the I-E subregion to restriction sites recognized by I- A/E-restricted T cells (1982) (8)
Dendritic cell internalization of α-galactosylceramide from CD8 T cells induces potent antitumor CD8 T-cell responses. (2011) (8)
Antigen-presenting cells for Lyt-2+ cells. II. Primary mixed-lymphocyte reactions stimulated by la+ dendritic cells and la −peritoneal exudate cells (1989) (8)
On the TRAIL of homeostatic memory T cells (2006) (7)
The thymus and T cell death. (1996) (7)
T cell–B cell collaboration (2017) (7)
Factors influencing transmission. (1967) (7)
QUANTITATIVE F EATURES OF A SANDWICH RADIOIMMUNOLABEL ING T ECHNIQUE FOR LYMPHOCYTE SURFACE R ECEPTORS (1972) (6)
The influence of H-2 gene products on cell-mediated and humoral immune responses. (1977) (6)
Measurement of T and B Cell Turnover with Bromodeoxyuridine (1996) (6)
Spontaneous Proliferation of CD4+ T Cells in RAG-Deficient Hosts Promotes Antigen-Independent but IL-2-Dependent Strong Proliferative Response of Naïve CD8+ T Cells (2018) (6)
Hemopoietic reconstitution obtained in F1 hybrids by grafting of parental marrow cells. (1976) (6)
The proliferation response of T lymphocytes to alloantigens in irradiated mice: a mixed lymphocyte reaction in vivo. (1973) (6)
Mixed Lymphocyte Reaction (1998) (5)
Constructing artificial antigen-presenting cells from Drosophila cells. (1997) (5)
A major histocompatibility complex class I – dependent subset of memory phenotype CD 8 + cells (2006) (5)
CELL-TO-CELL INTERACTION I N T HE I MMUNE RESPONSE VIII. RADIOSENSITIVIT¥ OF THYMuS-DERIVED LYMPHOCYTES*~ (1972) (4)
Mls antigens: immunity and tolerance. (1992) (4)
Unresponsiveness of MRL/MP-lpr/lpr mice to antigen given subcutaneously in adjuvant: partial restoration of response after local injection of B cells. (1987) (4)
Cell Expansion without Lymphopenia Cell Development and Induce Homeostatic T IL-7 / Anti-IL-7 mAb Complexes Restore (2008) (4)
ACUTE RENAL FAILURE COMPLICATING INTRAVENOUS CHOLANGIOGRAPHY IN A PATIENT WITH DUBIN‐JOHNSON SYNDROME (1969) (4)
The Power of Dilution: Using Adoptive Transfer To Study TCR Transgenic T Cells (2013) (4)
The thymus and central tolerance. (2001) (4)
Can self/nonself discrimination be explained entirely by clonal deletion? (1992) (4)
Redefining the Foreign Antigen and Self-Driven Memory CD4+ T-Cell Compartments via Transcriptomic, Phenotypic, and Functional Analyses (2022) (4)
Selective allogenic donor T cell subsets in experimental bone marrow transplantation. (1989) (3)
T/B collaboration in vivo vs. in vitro. (1984) (3)
Antigen-presenting cells for Lyt-2+ cells. II. Primary mixed-lymphocyte reactions stimulated by Ia+ dendritic cells and Ia- peritoneal exudate cells. (1989) (3)
Migratory Properties and Radiosensitivity of Lymphocytes (1985) (3)
Glimpsing the real CD4+ T cell response (2010) (2)
Counting on homeostasis: governing the size and composition of lymphocyte pools (2005) (2)
Foeto-placental iron studies. (1967) (2)
T cell recognition of antigen in vivo: Role of the H-2 complex (1980) (2)
The retroelement Lx9 puts a brake on the immune response to virus infection (2022) (2)
THREE SITUATIONS IN WHICH HELPER T CELLS FAIL TO COLLABORATE WITH H2-NONIDENTICAL B CELLS (1978) (2)
Pillars Article: T-Cell Apoptosis Detected In Situ during Positive and Negative Selection in the Thymus. Nature. 1994. 372: 100-103. (2018) (2)
Proliferation of activated thymocytes in mixed lymphocyte reactions. (1973) (2)
Rat stem cells developing in irradiated SCID mice fail to become tolerized and cause lethal graft-versus-host disease. (1997) (2)
H-2-restriction of T cells mediating lethal graft-versus-host-disease to minor histocompatibility determinants. (1982) (2)
Five types of lymphocytes (Ig-theta-, Ig-theta+weak, Ig-theta+strong, Ig+theta- and Ig+theta+) characterized by double immunofluorescence and electrophoretic mobility. Organ distribution in normal and nude mice. (1975) (2)
T-cell tolerance to H-2 molecules: role of the thymus. (1989) (2)
A season for midwinter immunology (2002) (2)
Remembering things past (2011) (1)
Rat T Cell Responses to Superantigens . II . Ailelic Differences in V 38 . 2 and V 38 . 5 3 Chains Determine Responsiveness to Staphylococcal Enterotoxin B and Mouse Mammary Tumor Virus-encoded Products (2003) (1)
CD70–CD27 ligation between neural stem cells and CD4+ T cells induces Fas–FasL-mediated T-cell death (2013) (1)
Pillars Article: Antigen-Induced Selective Recruitment of Circulating Lymphocytes. Cell. Immunol. 1971. 2: 171–181. (2006) (1)
HOW DO THYMIC H-2 DETERMINANTS CONTROL T CELL DEVELOPMENT AND WHAT IS THE SIGNIFICANCE OF ALLOREACTIVITY (1980) (1)
FURTHER EVIDENCE FOR CLONAL DELETION OF HOST REACTIVE T CELLS IN X-IRRADIATION CHIMERAS (1976) (1)
Receptors for immunoglobulin on b lymphocytes and cells of a plasma cell tumor. Abstr. (1971) (1)
Cells inducing tolerance to Mls and H-2 antigens. (1991) (1)
Corrigendum: Regulation of naive T cell function by the NF-κB pathway (2007) (1)
Presidential Address to The American Association of Immunologists (1999) (1)
H-2-RESTRICTED PRESENTATION OF ANTIGEN TO T HELPER CELLS IN VIVO1 (1980) (1)
T/B collaboration in vivo vs. in vitro (1984) (1)
H-2 Gene Control of T-B Collaboration in Vivo (1978) (1)
Protection against graft-versus-host disease by large doses of donor CD4+ T cells: a novel approach to bone marrow transplantation. (1993) (1)
27 – Anti-H-2 Reactivity of Mls-Specific T Cell Clones (1982) (1)
T Memory Cells: Quality not Quantity Dispatch (2002) (1)
WS/PP-045a-05 P-selectin glycoprotein ligand-1 (PSGL-1) controls suppressor activity by CD4+CD25+FOXP3+ regulatory T cells (2010) (0)
Characterization of Target In jury of Murine Acute Graft-versus-host Disease Directed to Multiple Minor Histocompatibility Antigens Elicited by Either CD 4 + or CD 8 + Effector Cells (2007) (0)
IFN-Dependent Pathways for Stimulation of Memory CD8+ Cells (2002) (0)
Impact of Graft-Resident Leucocytes on Treg Mediated Skin Graft Survival (2021) (0)
Systematic approach to explore molecular mechanism for TCR‐mediated LFA‐1 activation: Modulation of TCR signaling by AMP‐activated protein kinase (2008) (0)
IL-2AB/IL-2 complexes induce regulatory T cell expansion limiting chronic proteinuric renal injury (2011) (0)
recognition and its disorders (2009) (0)
Homeostatic maintenance of T cells and natural killer cells (2012) (0)
Augmenting the biological activity of IL-15 with soluble IL-15Ralpha (95.21) (2007) (0)
T CELL RECOGNITION: A DIFFICULTY WITH THE TWO-RECEPTOR MODEL (1980) (0)
Negative selection of discrete subgroups of T helper cells restricted by determinants present on I-A and I-A/E molecules. (1982) (0)
ALLOGRAFT TOLERANCE AFTER IN VIVO EXPANSION OF TREGS WITH IL-2/IL-2 MAB COMPLEXES: 23 (2008) (0)
Mlsa-reactive t-cell lines retain reactivity for h-2 determinants. Abstr. (1980) (0)
Regulatory T cells (PP-045) (2010) (0)
Charles D. Surh 1961–2017 (2017) (0)
Influence of the H-2 Complex on the Response of T Cells to Sheep Erythrocytes in vivo (1981) (0)
Project completion summary sheet (1991) (0)
Augmenting CD8+ T Cell Responses with IL-15/sIL-15Rα Complexes (2007) (0)
Specific Unresponsiveness of Lymphocytes Transferred 24 h after In Vivo Exposure to Heterologous Erythrocytes (2003) (0)
Commentary: Staying alive - nave CD4 + T cell homeostasis (2007) (0)
IL-2/ IL-2 mAb treatment generates prolonged expansion and increased cytokine production by NKT cells (50.42) (2010) (0)
TOLERANCE INDUCTION TOWARDS DETERMINANTS OF THE MAJOR HISTOCOMPATIBILITY COMPLEX: EVIDENCE FOR DELETION OF T CELL SUBSETS (1975) (0)
GENERATING ALLOGRAFT TOLERANCE BY BAFF- DEPENDANT EXPANSION OF REGULATORY T CELLS: 736 (2008) (0)
Regulatory Cells T + Disease in the Absence of Foxp 3 IL-21 Contributes to Fatal Inflammatory (2014) (0)
Mls Antigens: Immunity and Tolerance (Part 2 of 2) (1992) (0)
A fundamental role for Interleukin-21 in germinal center antibody responses (38.21) (2009) (0)
Response to 'Efficient T cell receptor–mediated apoptosis in nonobese diabetic mouse thymocytes' (2003) (0)
Mls DETERMINANTS AND ANTI‐Mls RECEPTORS (1988) (0)
Strong immunogenicity of membrane nanovesicles from dendritic cells (2018) (0)
Editorial: Immunological Tolerance in Transplantation: More Than Deletion (2022) (0)
T CELLS AND THE PRIMARY IMMUNE RESPONSE (2002) (0)
Activation by IL-2 T Cell + Unique Features of Naive CD8 (0)
Tolerogenicity of Thymic Epithelial Cells: Studies with Allogeneic and Xenogeneic Chimeras (1994) (0)
Dual Nature of Type I Interferons in SARS-CoV-2-Induced In ﬂ ammation Trends in Immunology (2021) (0)
Role of the i-e subregion in t cell selection to antigen in vivo. Abstr. (1981) (0)
Evidence that t cell primary responses to mls locus is not under mhc gene control. Abstr. (1978) (0)
Experimental Medicine Edited by R Recognition of Viral Glycoproteins by Influenza Α-specific Cross-reactive Cytolytic Τ Lymphocytes* Materials and Methods (0)
EVIDENCE THAT STRONG Mls DETERMINANTS ARE NONPOLYMORPHIC1 (1981) (0)
Full Length NF-κB2 Controls Migratory Activity of Memory T Cells by Regulating Expression of CXCR4 in A Mouse Model of Sjögren’s Syndrome (2018) (0)
Separation of H-2 Kand H-2 D-restricted T Cells by Double Negative Selection (2003) (0)
T cells and memory lapses. (1997) (0)
Immunogenicity : proceedings of a UCLA Symposium held at Steamboat Springs, Colorado, January 21-28, 1989 (1990) (0)
Viewpoint T CELL TOLERANCE AND SELF/NONSELF DISCRIMINATION (1993) (0)
Erratum: On the TRAIL of homeostatic memory T cells (2006) (0)
Mls Antigens: Immunity and Tolerance (Part 1 of 2) (1992) (0)
Influence o f Ant igen Dose and Cost imulat ion on the Primary Response o f CD 8 + T Cells in Vitro By (2003) (0)
An|igen-presenling ceils for .nprimed T ceils (1989) (0)
T-cell-dependent lethal gvh disease following marrow transplantation across minor histocompatibility barriers in mice. Abstr. (1978) (0)
T-B collaboration in vivo: role of the major histocompatibility complex. (1980) (0)
The thymus and centraZ toZerance (2001) (0)
Mls a reactive thymus derived cell lines retain reactivity for h 2 determinants (1980) (0)
Antigen presentation to t helper cells in vivo. Abstr. (1980) (0)
SELECTIVE RECRUITMENT IN VIVO OF SUBSETS OF RECIRCULATING LYMPHOCYTES REACTIVE TO H2 DETERMINANTS (1976) (0)
B-Cells Can be Activated in More than One Way (2019) (0)
Different Intensities of BrdU labeling in Thymus vs . Spleen and LN (2003) (0)
Calcineurin-dependent negative regulation of CD94/NKG2A expression on naive CD8 (cid:1) T cells (2011) (0)
Triggering requirements for unprimed cd8 positive cells (1990) (0)
Professionals and amateurs Professional antigen-presenting cells, notably dendritic cells, play a key role in stimulating naive T cells - but nonprofessional antigen- presenting cells, such as fibroblasts, may also contribute to this process. (1995) (0)
Antigen-induced selective recruitment of circulating lymphocytes. 1971. (2006) (0)
BYSTANDER PROLIFERATION OF CD8+ T-CELLS IN-VIVO (1995) (0)
I. METHOD OF DETECTION AND FUNCTIONAL SIGNII~ICANCE* $ (1972) (0)
TABLE I Failure of TDL to Respond to SRC in Microcultures Unless Supplemented with Irradiated Syngeneic Spleen Cells or an Allogeneic Factor (2003) (0)
Detection and Direct Stimulation of Antigen‐specific T cells by Nanometric Membrane Vesicles Expressing pMHC Complexes (2008) (0)

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