Jonathan Van Blerkom
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Cell Biology
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Molecular Biology
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Biology
Jonathan Van Blerkom's Degrees
- PhD Cell Biology University of California, Berkeley
- Masters Molecular Biology Stanford University
- Bachelors Biology Stanford University
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(Suggest an Edit or Addition)Jonathan Van Blerkom's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. (2011) (1235)
- Structural interaction of cytoskeletal components (1981) (734)
- ATP content of human oocytes and developmental potential and outcome after in-vitro fertilization and embryo transfer. (1995) (621)
- The developmental potential of the human oocyte is related to the dissolved oxygen content of follicular fluid: association with vascular endothelial growth factor levels and perifollicular blood flow characteristics. (1997) (534)
- Istanbul consensus workshop on embryo assessment: proceedings of an expert meeting. (2011) (468)
- The expression of leptin and its receptors in pre-ovulatory human follicles. (1997) (357)
- Oocyte influences on early development: the regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo. (1997) (341)
- Mitochondrial function in the human oocyte and embryo and their role in developmental competence. (2011) (316)
- Differential mitochondrial distribution in human pronuclear embryos leads to disproportionate inheritance between blastomeres: relationship to microtubular organization, ATP content and competence. (2000) (286)
- Domains of high-polarized and low-polarized mitochondria may occur in mouse and human oocytes and early embryos. (2002) (261)
- Temporal and spatial aspects of fragmentation in early human embryos: possible effects on developmental competence and association with the differential elimination of regulatory proteins from polarized domains. (1999) (256)
- Mitochondria in human oogenesis and preimplantation embryogenesis: engines of metabolism, ionic regulation and developmental competence (2004) (255)
- Mitochondrial reorganization during resumption of arrested meiosis in the mouse oocyte. (1984) (233)
- Mitochondrial function in the human oocyte and embryo and their role in developmental competence. (2011) (231)
- Oocyte dysmorphism and aneuploidy in meiotically mature human oocytes after ovarian stimulation. (1992) (198)
- Mitochondrial transfer between oocytes: potential applications of mitochondrial donation and the issue of heteroplasmy. (1998) (190)
- Stabilization and the cytoplasmic ground substance in detergent-opened cells and a structural and biochemical analysis of its composition. (1981) (170)
- Cytogenetic, cellular, and developmental consequences of cryopreservation of immature and mature mouse and human oocytes (1994) (156)
- A microscopic and biochemical study of fragmentation phenotypes in stage-appropriate human embryos. (2001) (154)
- Cryopreservation of metaphase II human oocytes effects mitochondrial membrane potential: implications for developmental competence. (2004) (149)
- Mitochondria in human oogenesis and preimplantation embryogenesis: engines of metabolism, ionic regulation and developmental competence. (2004) (141)
- Qualitative patterns of protein synthesis in the preimplantation mouse embryo. I. Normal pregnancy. (1975) (120)
- Nuclear and cytoplasmic dynamics of sperm penetration, pronuclear formation and microtubule organization during fertilization and early preimplantation development in the human. (1995) (115)
- Microtubule mediation of cytoplasmic and nuclear maturation during the early stages of resumed meiosis in cultured mouse oocytes. (1991) (112)
- Inner mitochondrial membrane potential (ΔΨm), cytoplasmic ATP content and free Ca2+ levels in metaphase II mouse oocytes (2003) (107)
- Regulation of development in the fully grown mouse oocyte: chromosome-mediated temporal and spatial differentiation of the cytoplasm and plasma membrane. (1986) (107)
- Mitochondria in early mammalian development. (2009) (105)
- Microtubule mediation of cytoplasmic and nuclear maturation during the early stages of resumed meiosis in cultured mouse oocytes (1991) (102)
- Mitochondrial signaling and fertilization. (2007) (99)
- Development of preimplantation rabbit embryos in vivo and in vitro. (1973) (96)
- Structural relationship and posttranslational modification of stage-specific proteins synthesized during early preimplantation development in the mouse. (1981) (94)
- The cellular basis of mammalian reproduction (1979) (91)
- Differential effects of repeated ovarian stimulation on cytoplasmic and spindle organization in metaphase II mouse oocytes matured in vivo and in vitro. (2001) (91)
- Development of preimplantation rabbit embryos in vivo and in vitro. I. An ultrastructural comparison. (1973) (90)
- Molecular differentiation in the preimplantation mouse embryo (1976) (89)
- Mitochondria in early mammalian development. (2009) (84)
- DNA strand breaks and phosphatidylserine redistribution in newly ovulated and cultured mouse and human oocytes: occurrence and relationship to apoptosis. (1998) (83)
- Occurrence and developmental consequences of aberrant cellular organization in meiotically mature human oocytes after exogenous ovarian hyperstimulation. (1990) (81)
- Patterns of polypeptide synthesis of porcine oocytes during maturation in vitro. (1977) (75)
- The oxidizing agent tertiary butyl hydroperoxide induces disturbances in spindle organization, c-meiosis, and aneuploidy in mouse oocytes. (1996) (74)
- Intrafollicular influences on human oocyte developmental competence: perifollicular vascularity, oocyte metabolism and mitochondrial function (2000) (74)
- Qualitative patterns of protein synthesis in the preimplantation mouse embryo. II. During release from facultative delayed implantation. (1975) (74)
- Mitochondria as regulatory forces in oocytes, preimplantation embryos and stem cells (2008) (73)
- Molecular differentiation of the rabbit ovum. I. During oocyte maturation in vivo and in vitro. (1978) (72)
- High-polarized (Delta Psi m(HIGH)) mitochondria are spatially polarized in human oocytes and early embryos in stable subplasmalemmal domains: developmental significance and the concept of vanguard mitochondria. (2006) (66)
- Preimplantation human embryonic development from polypronuclear eggs after in vitro fertilization. (1984) (66)
- A scanning electron microscopic study of the luteo-follicular complex. II. Events leading to ovulation. (1975) (64)
- Regulatory roles for mitochondria in the peri-implantation mouse blastocyst: possible origins and developmental significance of differential DeltaPsim. (2006) (63)
- Cytogenetic analysis of living human oocytes: cellular basis and developmental consequences of perturbations in chromosomal organization and complement. (1988) (63)
- First births with a simplified culture system for clinical IVF and embryo transfer. (2014) (62)
- Molecular differentiation of the rabbit ovum. II. During the preimplantation development of in vivo and in vitro matured oocytes. (1978) (59)
- Ultrastructure of Reproduction (1984) (55)
- Development of human embryos to the hatched blastocyst stage in the presence or absence of a monolayer of Vero cells (1993) (54)
- Maturation at high frequency of germinal-vesicle-stage mouse oocytes after cryopreservation: alterations in cytoplasmic, nuclear, nucleolar and chromosomal structure and organization associated with vitrification (1989) (54)
- The Influence of Intrinsic and Extrinsic Factors on the Developmental Potential and Chromosomal Normality of the Human Oocyte (1996) (53)
- Fertilization and early embryology: A retrospective analysis of unfertilized and presumed parthenogenetically activated human oocytes demonstrates a high frequency of sperm penetration (1994) (53)
- Programmed development in the mouse embryo. (1984) (52)
- Cellular and developmental biological aspects of bovine meiotic maturation, fertilization, and preimplantation embryogenesis in vitro. (1990) (51)
- Mitochondria as regulatory forces in oocytes, preimplantation embryos and stem cells. (2008) (51)
- Molecular and cellular aspects of facultative delayed implantation in the mouse. (1978) (50)
- A novel mechanism of vascular endothelial growth factor, leptin and transforming growth factor-beta2 sequestration in a subpopulation of human ovarian follicle cells. (1997) (50)
- The occurrence, recognition and developmental fate of pseudo-multipronuclear eggs after in-vitro fertilization of human oocytes. (1987) (49)
- The vascular character of ovarian follicular granulosa cells: phenotypic and functional evidence for an endothelial-like cell population. (2000) (47)
- Epigenetic Influences on Oocyte Developmental Competence: Perifollicular Vascularity and Intrafollicular Oxygen (1998) (47)
- Regulation of mitochondrial polarity in mouse and human oocytes: the influence of cumulus derived nitric oxide. (2008) (46)
- Occurrence and developmental consequences of aberrant cellular organization in meiotically mature human oocytes after exogenous ovarian hyperstimulation. (1990) (46)
- Evolution of the sperm aster after microinjection of isolated human sperm centrosomes into meiotically mature human oocytes. (1995) (45)
- Can the developmental competence of early human embryos be predicted effectively in the clinical IVF laboratory (1997) (44)
- Developmental failure in human reproduction associated with preovulatory oogenesis and preimplantation embryogenesis (1989) (44)
- Intrafollicular influences on human oocyte developmental competence: perifollicular vascularity, oocyte metabolism and mitochondrial function. (2000) (42)
- Preimplantation embryology: Sperm centrosome dysfunction: a possible new class of male factor infertility in the human (1996) (42)
- Development of human embryos to the hatched blastocyst stage in the presence or absence of a monolayer of Vero cells. (1993) (42)
- Epigenetic Influences on Oocyte Developmental Competence: Perifollicular Vascularity and Intrafollicular Oxygen (1998) (42)
- Structural relationship and posttranslational modification of stage-specific proteins synthesized during early preimplantation development in the mouse. (1981) (40)
- Inner mitochondrial membrane potential (DeltaPsim), cytoplasmic ATP content and free Ca2+ levels in metaphase II mouse oocytes. (2003) (39)
- Changes in the surface morphology of ovarian germinal epithelium during the reproductive cycle and in some pathological conditions: a correlative 3-dimensional analysis by transmission electron microscopy, scanning electron microscopy and high voltage electron microscopy. (1980) (37)
- The developmental ability of human oocytes penetrated at the germinal vesicle stage after insemination in vitro. (1994) (36)
- The fine structural development of preimplantation mouse parthenotes. (1976) (33)
- Sperm centrosome dysfunction: a possible new class of male factor infertility in the human. (1996) (33)
- A plea for caution and more research in the 'experimental' use of ionophores in ICSI. (2015) (33)
- Molecular differentiation of the rabbit ovum. III. Fertilization-autonomous polypeptide synthesis. (1978) (33)
- Implications of cytoskeletal interactions for cellular architecture and behavior. (1982) (31)
- Ultrastructure of Human Gametogenesis and Early Embryogenesis (2011) (30)
- Structural organization of the cytoplasm. (1982) (30)
- 4 – Methods for the High-Resolution Analysis of Protein Synthesis: Applications to Studies of Early Mammalian Development (1978) (30)
- Morphodynamics of outgrowths of mouse trophoblast in the presence and absence of a monolayer of uterine epithelium. (1981) (29)
- Maturation at high frequency of germinal-vesicle-stage mouse oocytes after cryopreservation: alterations in cytoplasmic, nuclear, nucleolar and chromosomal structure and organization associated with vitrification. (1989) (25)
- The Influence of Intrinsic and Extrinsic Factors on the Developmental Potential and Chromosomal Normality of the Human Oocyte (1996) (24)
- Scanning Electron Microscopy of the Mammalian Ovary (1980) (22)
- Occurrence of maternal and paternal spindles in unfertilized human oocytes: possible relationship to nucleation defects after silent fertilization. (2004) (22)
- Stabilization of the cytoplasmic ground substance in detergent-opened cells and a structural and biochemical analysis of its composition ( cytoskeleton / microtrabecular network / microfilaments / heavy meromyosin decoration ) (22)
- Persistence of embryonic RNA synthesis during facultative delayed implantation in the mouse. (1979) (21)
- Sperm attachment and penetration competence in the human oocyte: a possible aetiology of fertilization failure involving the organization of oolemmal lipid raft microdomains influenced by the ΔΨm of subplasmalemmal mitochondria. (2013) (19)
- A retrospective analysis of unfertilized and presumed parthenogentically activated human oocytes demonstrates a high frequency of sperm penetration. (1994) (19)
- Intrinsic and Extrinsic Patterns of Molecular Differentiation during Oogenesis, Embryogenesis, and Organogenesis in Mammals (1981) (17)
- Atlas of human female reproductive function : ovarian development to early embryogenesis after in vitro fertilization (2006) (17)
- Cryopreservation of the mammalian oocyte. (1991) (16)
- A scanning electron microscopic study of the luteo-follicular complex (1978) (15)
- Essential IVF : basic research and clinical applications (2004) (15)
- The tWE lab Simplified IVF Procedure: First Births after freezing/thawing (2014) (14)
- The patterns of protein synthesis during foetal and neonatal organ development in the mouse are remarkably similar. (1982) (14)
- Translocation of the subplasmalemmal cytoplasm in human blastomeres: possible effects on the distribution and inheritance of regulatory domains. (2007) (12)
- Molecular differentiation of the rabbit ovum. III. Fertilization-autonomous polypeptide synthesis. (1979) (12)
- Evolution of the sperm aster after microinjection of isolated human sperm centrosomes into meiotically mature human oocytes (1995) (12)
- 11 – Protein Synthesis during Oogenesis and Early Embryogenesis in the Mammal (1985) (11)
- In Vitro Attachment and Outgrowth of Mouse Trophectoderm (1981) (10)
- Changes in the surface morphology of the rabbit endometrium related to the estrous and progestational stages of the reproductive cycle (1978) (9)
- Ultrastructure of reproduction : gametogenesis, fertilization, and embryogenesis (1984) (9)
- Dispermic fertilization of human oocytes. (1991) (8)
- Can the developmental competence of early human embryos be predicted effectively in the clinical IVF laboratory? (1997) (7)
- The Biological basis of early human reproductive failure : applications to medically-assisted conception (1994) (7)
- Translocation of the subplasmalemmal cytoplasm in human blastomeres: possible effects on the distribution and inheritance of regulatory domains. (2007) (7)
- Extragenomic Regulation and Autonomous Expression of a Developmental Program in the Early Mammalian Embryo a (1985) (7)
- A scanning electron microscopic study of rabbit spermatozoa in the female reproductive tract following coitus (1975) (6)
- Cell and Molecular Biology of Meiotic Maturation of the Mammalian Oocyte (1980) (6)
- Ganglioside-enriched microdomains define an oolemma that is functionally polarized with respect to fertilizability in the mouse. (2016) (6)
- The Enigma of Fragmentation in Early Human Embryos: Possible Causes and Clinical Relevance (2004) (6)
- Computer-assisted analysis demonstrates that polypeptides induced by natural and recombinant human interferon-alpha are the same and that some have related primary structures. (1983) (5)
- Morphodynamics of nuclear and cytoplasmic reorganization during the resumption of arrested meiosis in the mouse oocyte. (1989) (5)
- Extragenomic regulation and autonomous expression of a developmental program in the early mammalian embryo. (1985) (5)
- Effect of cryopreservation on mitochondrial membrane potential in human oocytes (2002) (4)
- The origin and detection of chromosomal abnormalities in meiotically mature human oocytes obtained from stimulated follicles and after failed fertilization in vitro. (1989) (3)
- Molecular Mining of Follicular Fluid for Reliable Biomarkers of Human Oocyte and Embryo Developmental Competence (2012) (3)
- The Role of the Plasma Membrane and Pericortical Cytoplasm in Early Mammalian Development (2013) (3)
- Multiyear outcomes using sibling oocytes demonstrates safety and efficacy of a simplified culture system consistent with use in a low-cost IVF setting. (2022) (3)
- Single Embryo Transfer: An overview of determinants of oocyte and embryo developmental competence: specificity, accuracy and applicability in clinical IVF (2008) (3)
- Oocyte selection in contemporary clinical IVF: do follicular markers of oocyte competence exist? (2007) (3)
- Identification and characterization of glycoproteins secreted by the skin of the day 16 fetal mouse. (1984) (2)
- NEW RESEARCH HORIZON Mitochondrial signaling and fertilization (2007) (2)
- Design and Development of Simplified, Low-Cost Technologies for Clinical IVF: Applications in High- and Low-Resource Settings (2019) (2)
- Morphodynamic aspects of the ovarian superficial epithelium as revealed by transmission, scanning and high voltage electron microscopy (1979) (2)
- Symposium: Genetic and epigenetic aspects of assisted reproduction Mitochondria as regulatory forces in oocytes, preimplantation embryos and stem cells (2008) (1)
- Perinatal outcome of babies born after using a simplified IVF culture system versus ICSI with sibling oocytes: a prospective cohort study. (2022) (1)
- Human in vitro fertilization in a private program: Reproductive genetics in vitro, P.C. (1984) (1)
- Session 03: The impact of new clinical evidence in (early) pregnancy (2013) (1)
- Clinical applications in symmetry, asymmetry and polarity in early human development (2003) (1)
- Mitochondrial Activity as a Biomarker of Gamete and Embryo Health (2013) (1)
- The Role of Mitochondria in the Establishment of Developmental Competence in Early Human Development (2012) (1)
- NEW RESEARCH HORIZON Regulation of mitochondrial polarity in mouse and human oocytes: the influence of cumulus derived nitric oxide (2008) (0)
- O-013 Increased density of uterine natural killer cells in the peri- implantation endometrium is associated with inadequate decidualization, local cortisol deficiency, and impaired induction of metabolic enzymes (0)
- 50 MITOCHONDRIA AND DEVELOPMENTAL COMPETENCE (2010) (0)
- Comparison of ionophore induced Ca2+ release in fresh and cryopreserved oocytes (2003) (0)
- Mitochondria as elements of developmental competence and regulation in the oocyte and preimplantation-stage embryo (2008) (0)
- 49 PLASMA MEMBRANE REMODELING GAIN AND LOSS OF FUNCTION DURING OOCYTE MATURATION AND EARLY DEVELOPMENT (2010) (0)
- O▪5 Selecting the right embryo (2005) (0)
- The use of Doppler ultrasonography and power angiography to select oocytes for IVF based on perifollicular blood flow and vascularity: an update (2006) (0)
- Personal recollections of Bob Edwards (2011) (0)
- Perivitelline threads: an overlooked feature of cleavage-stage human embryos or an epiphenomenon in search of a function? (2017) (0)
- Molecular Mining of Follicular Fluid for Reliable Biomarkers of Human Oocyte and Embryo Developmental Competence (2019) (0)
- Promising Perinatal Outcome after Using a Simplified Low-Cost IVF Culture System Specifically Designed for Resource-Poor Countries (2023) (0)
- The Role of Mitochondria in the Establishment of Developmental Competence in Early Human Development (2019) (0)
- The organization and role of the subplasmalemmal cytoplasm in the establishment of oocyte and embryo competence (2006) (0)
- New Research Horizon: Mitochondrial signalling and oocyte maturation and fertilization (2007) (0)
- O-214. Perifollicular vascularity and oocyte developmental competence (1999) (0)
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