Jonathan Waxman
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British physician, oncologist and author
Jonathan Waxman 's AcademicInfluence.com Rankings
Jonathan Waxman philosophy Degrees
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Philosophy
Why Is Jonathan Waxman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Jonathan Hugh Waxman , founder and president of Prostate Cancer UK, is emeritus Professor of Oncology at Imperial College London, and author of four novels including The Elephant in the Room. He is a clinician who has helped develop new treatments for cancer, which are now part of standard practice.
Jonathan Waxman 's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion. (1993) (458)
- The estrogen receptor-α-induced microRNA signature regulates itself and its transcriptional response (2009) (329)
- Wnt/β-catenin signalling in prostate cancer (2012) (242)
- Impact of analytical bias in metabonomic studies of human blood serum and plasma. (2006) (223)
- Bone metastasis in prostate cancer: emerging therapeutic strategies (2011) (200)
- The effects of gonadotrophin releasing hormone analogues in prostate cancer are mediated through specific tumour receptors. (1990) (157)
- Wnt-11 promotes neuroendocrine-like differentiation, survival and migration of prostate cancer cells (2010) (156)
- COX inhibitors and breast cancer (2006) (146)
- Circulating microRNAs as potential new biomarkers for prostate cancer (2013) (145)
- Inhibition of glycogen synthase kinase-3 represses androgen receptor activity and prostate cancer cell growth (2004) (132)
- FTY720 (fingolimod) sensitizes prostate cancer cells to radiotherapy by inhibition of sphingosine kinase-1. (2010) (131)
- Analysis of Wnt Gene Expression in Prostate Cancer (2004) (121)
- Regulation of prostate cell growth and morphogenesis by Dickkopf-3 (2006) (120)
- Serum metalloproteinases and their inhibitors: markers for malignant potential. (1994) (120)
- Phase II study of paclitaxel in pretreated patients with locally advanced/metastatic cancer of the bladder and ureter. (1997) (118)
- E‐cadherin expression in bladder cancer using formalin‐fixed, paraffin‐embedded tissues: Correlation with histopathological grade, tumour stage and survival (1995) (114)
- Chemosensitizing effects of sphingosine kinase-1 inhibition in prostate cancer cell and animal models (2008) (112)
- CD3 limits the efficacy of TCR gene therapy in vivo. (2011) (110)
- Androgens target prohibitin to regulate proliferation of prostate cancer cells (2004) (98)
- Bone metastasis in prostate cancer: emerging therapeutic strategies (2011) (96)
- Adjuvant mitozantrone chemotherapy in advanced prostate cancer (2000) (91)
- miR‐515‐5p controls cancer cell migration through MARK4 regulation (2016) (87)
- Visualising Androgen Receptor Activity in Male and Female Mice (2013) (85)
- Prohibitin, a protein downregulated by androgens, represses androgen receptor activity (2007) (80)
- Clinical significance of heat shock protein-70 expression in bladder cancer. (2003) (78)
- Altered gamma-catenin expression correlates with poor survival in patients with bladder cancer. (1998) (78)
- Mechanisms of androgen receptor signalling via steroid receptor coactivator-1 in prostate. (2004) (77)
- Microarray coupled to quantitative RT–PCR analysis of androgen-regulated genes in human LNCaP prostate cancer cells (2009) (74)
- Downregulation of microRNA-515-5p by the estrogen receptor modulates sphingosine kinase 1 and breast cancer cell proliferation. (2013) (70)
- Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer (2018) (69)
- COX and cancer. (2005) (68)
- Analysis of stromal-epithelial interactions in prostate cancer identifies PTPCAAX2 as a potential oncogene. (2002) (66)
- FUS/TLS is a novel mediator of androgen-dependent cell-cycle progression and prostate cancer growth. (2011) (65)
- Immunotherapy for renal cell cancer. (1998) (61)
- The involvement of sphingosine kinase 1 in LPS‐induced Toll‐like receptor 4‐mediated accumulation of HIF‐1α protein, activation of ASK1 and production of the pro‐inflammatory cytokine IL‐6 (2011) (56)
- EXPRESSION OF THE TYPE 1 TYROSINE KINASE GROWTH FACTOR RECEPTORS EGF RECEPTOR, c‐erbB2 AND c‐erbB3 IN BLADDER CANCER (1996) (54)
- Manipulating prohibitin levels provides evidence for an in vivo role in androgen regulation of prostate tumours (2009) (53)
- Sphingosine kinase 1 inhibition sensitizes hormone‐resistant prostate cancer to docetaxel (2009) (52)
- Metabolic signatures of malignant progression in prostate epithelial cells. (2011) (52)
- Gene therapy for prostate cancer. (1997) (51)
- Serum levels of IL-6 and TNF-α correlate with clinicopathological features and patient survival in patients with prostate cancer (2004) (51)
- Circulating sphingosine-1-phosphate and erythrocyte sphingosine kinase-1 activity as novel biomarkers for early prostate cancer detection (2012) (50)
- Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway (2014) (49)
- Distinct expression and activity of GSK‐3α and GSK‐3β in prostate cancer (2012) (49)
- Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer (2009) (48)
- Langerhans cell histiocytosis: old disease new treatment. (2011) (48)
- Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer (2011) (45)
- Detection of Wilms' Tumor Antigen–Specific CTL in Tumor-Draining Lymph Nodes of Patients with Early Breast Cancer (2006) (44)
- Androgen Receptor Is Targeted to Distinct Subcellular Compartments in Response to Different Therapeutic Antiandrogens (2004) (44)
- AGE‐modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival (2015) (44)
- Control of emesis in bowel obstruction in terminally ill patients (1992) (43)
- Differentially expressed genes in hormone refractory prostate cancer: association with chromosomal regions involved with genetic aberrations. (1999) (43)
- Endo180 expression with cofunctional partners MT1-MMP and uPAR-uPA is correlated with prostate cancer progression. (2009) (40)
- The cost of a QALY. (2010) (37)
- Inflammatory cytokines and aromatase inhibitor-associated musculoskeletal syndrome: a case–control study (2010) (36)
- The partial purification and characterization of GnRH-like activity from prostatic biopsy specimens and prostatic cancer cell lines (1990) (35)
- The experiences of cancer patients. (2011) (35)
- Downregulation of Dickkopf-3 disrupts prostate acinar morphogenesis through TGF-&bgr;/Smad signalling (2013) (34)
- Protective effect of stromal Dickkopf-3 in prostate cancer: opposing roles for TGFBI and ECM-1 (2018) (34)
- Sphingosine kinase 1 contributes to leptin-induced STAT3 phosphorylation through IL-6/gp130 transactivation in oestrogen receptor-negative breast cancer (2014) (29)
- New drugs for prostate cancer (2012) (28)
- CRISPR-Mediated Reactivation of DKK3 Expression Attenuates TGF-β Signaling in Prostate Cancer (2018) (28)
- Tumours of the prostate. (2001) (28)
- Dickkopf-3 regulates prostate epithelial cell acinar morphogenesis and prostate cancer cell invasion by limiting TGF-β-dependent activation of matrix metalloproteases. (2016) (28)
- Advances in tumour immunotherapy. (2008) (26)
- Correlation between androgen receptor expression and FGF8 mRNA levels in patients with prostate cancer and benign prostatic hypertrophy. (1999) (24)
- A screen for transcription factor targets of Glycogen Synthase Kinase-3 highlights an inverse correlation of NFκB and Androgen Receptor Signaling in Prostate Cancer (2014) (24)
- Early chemotherapy in prostate cancer (2008) (24)
- IL15 Can Reverse the Unresponsiveness of Wilms' Tumor Antigen-Specific CTL in Patients with Prostate Cancer (2009) (24)
- British urological surgery practice: 1. Prostate cancer. (1997) (23)
- Circulating nucleic acids as biomarkers of prostate cancer. (2013) (23)
- Survival Outcome and EMT Suppression Mediated by a Lectin Domain Interaction of Endo180 and CD147 (2014) (23)
- Doctors should not discuss resuscitation with terminally ill patients (2003) (22)
- Androgen deprivation in males is associated with decreased central arterial compliance and reduced central systolic blood pressure (2000) (21)
- Post-transplantation lymphoproliferative disease. (1997) (21)
- Reducing prohibitin increases histone acetylation, and promotes androgen independence in prostate tumours by increasing androgen receptor activation by adrenal androgens (2011) (21)
- Nuclear export of α-catenin: overlap between nuclear export signal sequences and the β-catenin binding site (2004) (21)
- Second messenger up‐regulation of androgen receptor gene transcription is absent in androgen insensitive human prostatic carcinoma cell lines, PC‐3 and DU‐145 (1996) (21)
- Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces (2015) (19)
- TGFβ1–Endo180‐dependent collagen deposition is dysregulated at the tumour–stromal interface in bone metastasis (2012) (19)
- Endo180 modulation by bisphosphonates and diagnostic accuracy in metastatic breast cancer (2012) (18)
- Inhibiting estrogen responses in breast cancer cells using a fusion protein encoding estrogen receptor-α and the transcriptional repressor PLZF (2005) (18)
- Kisspeptin is released from human prostate cancer cell lines but plasma kisspeptin is not elevated in patients with prostate cancer. (2010) (18)
- Characterisation of the androgen regulation of glycine N-methyltransferase in prostate cancer cells (2013) (17)
- Prostate cancer (2002) (16)
- The architecture of cancer. (1992) (15)
- Nuclear export of alpha-catenin: overlap between nuclear export signal sequences and the beta-catenin binding site. (2004) (15)
- Localised prostate cancer: can we do better? (2000) (14)
- Anti-androgens in treatment of prostate cancer (1995) (13)
- The management of carcinoid tumours. (1998) (13)
- Genetic alterations in bladder cancer (1993) (13)
- Patterns of survival in patients with advanced Hodgkin's disease (HD) treated in a single centre over 20 years. (1992) (13)
- Wnt-11 as a Potential Prognostic Biomarker and Therapeutic Target in Colorectal Cancer (2019) (12)
- The current status of scientific research and hormonal treatments for carcinoma of the prostate. (1991) (12)
- miR-515-5 p controls cancer cell migration through MARK 4 regulation (2016) (11)
- Antiandrogens Act as Selective Androgen Receptor Modulators at the Proteome Level in Prostate Cancer Cells* (2015) (10)
- Voodoo dolls and the cancer patient: patients do trust their doctors. (2009) (10)
- PSA and prostate cancer diagnosis. (1996) (10)
- Lung Aspergillosis in renal cell carcinoma patient treated with sunitinib. (2012) (9)
- Silencing of androgen-regulated genes using a fusion of AR with the PLZF transcriptional repressor (2004) (9)
- Improving outcomes in early prostate cancer: Part II – neoadjuvant treatment (2006) (9)
- Clodronate for multiple myeloma (1993) (9)
- The prognostic significance of serum levels of tumour necrosis factor- alpha and interleukin-6 and their association with cachexia in patients with prostate cancer. (2004) (8)
- Is prostate cancer worth diagnosing? (1995) (8)
- Circulating sphingosine-1-phosphate inversely correlates with chemotherapy-induced weight gain during early breast cancer (2010) (7)
- The promiscuous receptor (2009) (7)
- Engineered repressors are potent inhibitors of androgen receptor activity (2014) (7)
- Preserving fertility in Hodgkin's disease. (1987) (7)
- Gene therapy for prostate cancer (2004) (6)
- Gonadotrophin-releasing hormone: physiological significance and relevance to cancer. (1991) (6)
- Dietary fat and breast cancer. (2006) (6)
- A distinct inflammatory marker pattern in patients with aromatase inhibitor (AI)-induced musculoskeletal symptoms. (2009) (6)
- Downregulation of Dickkopf-3 disrupts prostate acinar morphogenesis through TGF-β/Smad signalling (2013) (6)
- Medical registrar training (1991) (5)
- Diet and prostate cancer (2004) (5)
- Epithelial mucin expression in bladder cancer: correlation with pathological and clinical parameters (2000) (5)
- Androgen resistance in prostate cancer (2008) (4)
- Clues from hypercalcaemia (2002) (4)
- Osteoporosis and prostate cancer (2003) (4)
- Molecular endocrinology of cancer (1996) (4)
- How are we looking after prostate cancer? (2003) (4)
- The Molecular Biology of Cancer (1984) (4)
- CLODRONATE FOR MULTIPLE MYELOMA. AUTHOR'S REPLY (1993) (4)
- The New endocrinology of cancer (1987) (3)
- Britain needs a national cancer institute (1998) (3)
- New treatments for kidney cancer (2008) (3)
- Autocrine stimulation by gonadotrophin-releasing hormone-like factors of human hormone-responsive prostate cancer cells in culture. (1990) (3)
- Current management of prostate cancer: dilemmas and trials. (2012) (3)
- New drugs for prostate cancer? (1998) (3)
- Prostate cancer and endocrine therapy (1997) (3)
- Improving outcomes in early prostate cancer: Part I – adjuvant treatment (2006) (3)
- British urological surgery practice: 2. Renal, bladder and testis cancer. (1998) (3)
- Lessons from Ives: Elements of Charles Ives’s musical language in the film scores and symphonic works of Bernard Herrmann (2011) (3)
- In vitro deregulation of markers characteristic of human prostate epithelial cells. (2004) (2)
- Chemotherapy for prostate cancer. (2001) (2)
- The Molecular Biology of Prostate Cancer (2005) (2)
- All My Trials (2012) (2)
- Endo 180 modulation by bisphosphonates and diagnostic accuracy in metastatic breast cancer (2013) (2)
- Smoker’s Cough (2012) (2)
- In Foreign Parts (2014) (2)
- Immunosuppressive drug FTY720 sensitizes prostate cancer cells to radiotherapy by inhibition of sphingosine kinase‐1. (2008) (2)
- MiR-27a-3p: An AR-modulatory microRNA with a distinct role in prostate cancer progression and therapy. (2020) (2)
- A Very Unusual Presentation of Metastatic Transitional Cell Carcinoma of the Bladder (2007) (2)
- More brickbats than bouquets? (2010) (2)
- Hypercalcaemia--new mechanisms for old observations. (1990) (2)
- Do we know what's best for prostate cancer? (1996) (2)
- Mediated by a Lectin Domain Interaction of Endo 180 and CD 147 (2015) (2)
- ‘TIME, GENTLEMEN, PLEASE’ FOR WATCHFUL WAITING IN PROSTATE CANCER? (2007) (1)
- A circulating miRNA signature to help prognosticate at prostate cancer diagnosis. (2017) (1)
- The Role of Androgen Receptor Mutations in Progression of Prostate Cancer (2013) (1)
- Changing Views on Living Organisms (2013) (1)
- Cancer esearch apeutics , Targets , and Chemical Biology 720 ( Fingolimod ) Sensitizes Prostate Cancer Cells to R iotherapy by Inhibition of Sphingosine Kinase-1 (2010) (1)
- Hormone Therapy for Prostate Cancer (2008) (1)
- The gonadal effects of cancer and its treatment (1985) (1)
- Differential response of patients with metastatic renal cell carcinoma to sunitinib according to the Fuhrman grading of their targeted tumors. (2011) (1)
- Advances in the treatment of pancreatic neuroendocrine tumours. (2012) (1)
- Treatment options in urological cancer (2002) (1)
- Mechanisms of androgen receptor signalling via SRC1 in prostate (2003) (1)
- 941 Loss of Dickkopf-3 expression impairs prostate acinar morphogenesis via aberrant TGF-β/Smad signalling activation (2013) (1)
- Urological cancers in clinical practice (2007) (1)
- Evaluating the Wilms' tumour antigen 1 as a target for the immunotherapy of prostate cancer (2008) (1)
- Cancer and the law : a medical negligence guide (1999) (1)
- Prefacing Music in the Concert Hall: Program Books, Composer Commentaries, and the Conflict over Musical Meaning (2012) (1)
- An Introduction to Medicine (2014) (1)
- Information Theory and Neuroscience (2009) (1)
- In vitro deregulation of marhers characteristic of human prostate epithelial cells Tissue & Cell (2004) (0)
- Genetic alterations in bladder cancer. (1993) (0)
- Androgen responses in the LNCaP prostate cancer cell line, an investigation using proteomics technology (2003) (0)
- A hypothesis-generating exploratory analysis of efficacy and safety of abiraterone acetate (AA) in African American (Af Am) patients (pts) with metastatic castration-resistant prostate cancer (mCRPC). (2012) (0)
- Frizzled-8 integrates Wnt-11 and transforming growth factor-β signaling in prostate cancer (2018) (0)
- Abstract #LB-305: Genome wide screen of estrogen receptor-\#945; regulated microRNAs reveals a negative autoregulatory feedback loop (2009) (0)
- Sequence analysis of the androgen receptor exon 1 CAG trinucleotide repeats in several cell lines (prostatic and non-prostatic) and in microdissected prostatic (1997) (0)
- Cytotoxic T cells specific for the Wilms' tumor protein are present in patients with breast cancer and are of sufficient avidity to kill breast cancer cells (2005) (0)
- The Wilms' Tumour Antigen 1 (WT1) as a Potential Target Antigen for the Immunotherapy of Solid Tumours (2003) (0)
- Tumor-associated Endo180 requires stromal-derived LOX to promote metastatic prostate cancer cell migration on human ECM surfaces (2015) (0)
- Endo180 expression by tumour cells with an invasive phenotype correlates with prostate cancer progression (2008) (0)
- Expression of WNT11 represess androgen receptor activity and is increased in androgen-independent prostate cancer cells (2003) (0)
- INTERNATIONAL VARIATIONS IN BREAST-CANCER INCIDENCE (1977) (0)
- 11 Tumour Flare in Hormonal Therapy (1988) (0)
- Comprar Diabetes and the Eye, CD-ROM | Jonathan Waxman | 9780727913814 | Wiley (2009) (0)
- 1075 Sphingosine kinase 1 inhibition sensitizes hormone-resistant prostate and breast cancer cells to docetaxel (2009) (0)
- Advances in hormone-dependent malignancies (1994) (0)
- Authors' reply: Expanding horizons in metastatic prostate cancer treatment (2011) (0)
- The Pleasures of Undergraduate Research (2014) (0)
- Comprar Treatment Options in Urological Cancer | Michael Clement | 9780632055890 | Wiley (2009) (0)
- 777 CRUCIAL ROLE OF DICKKOPF-3 IN PROSTATE MORPHOGENESIS IN VITRO AND IN VIVO (2012) (0)
- Explorer Endo 180 modulation by bisphosphonates and diagnostic accuracy in metastatic breast cancer (2017) (0)
- Méthodes facilitant le diagnostic du cancer de la prostate (2009) (0)
- 278 SECRETED FRIZZLED RELATED PROTEIN-1 IS A NEGATIVE REGULATOR OF ANDROGEN RECEPTOR SIGNALING IN PROSTATE CANCER (2011) (0)
- A hypothesis-generating exploratory analysis of efficacy and safety of abiraterone acetate (AA) in African American (Af Am) patients (pts) with metastatic castration-resistant prostate cancer (mCRPC). (2012) (0)
- A signature of miRNAs in the blood to help prognosticate prostate cancer at the time of diagnosis. (2017) (0)
- Carcinoma of the Prostate: Science and Treatment (1996) (0)
- 654 Crucial role of Dickkopf-3 in prostate morphogenesis in vitro and in vivo (2012) (0)
- Inhibiting estrogen responses in breast cancer cells using a fusion protein encoding estrogen receptor-α and the transcriptional repressor PLZF (2005) (0)
- Androgen pathway regulating microRNAs in prostate cancer progression and therapy (2016) (0)
- Abstract P2-02-03: The Collagen Receptor Endo180: A Metastatic Plasma Marker In Breast Cancer Modulated By Bisphosphonate Treatment (2012) (0)
- MiR-1271-5p: An AR-modulatory microRNA with a distinct role in prostate cancer progression, through SND1 and MORF4L1 interaction. (2019) (0)
- Erratum: Inhibiting estrogen responses in breast cancer cells using a fusion protein encoding estrogen receptor-α and the transcriptional repressor PLZF (Gene Therapy) (2005) vol. 12 (452-460) 10.1038/sj.gt.3302421) (2005) (0)
- Effect of CD3 on the efficacy of TCR gene therapy in vivo. (2011) (0)
- 802 LOSS OF DICKKOPF-3 EXPRESSION IMPAIRS PROSTATE ACINAR MORPHOGENESIS VIA ABERRANT TGF-β/SMAD SIGNALLING ACTIVATION (2013) (0)
- Androgen receptor is targeted to different sub-cellular compartments in response to therapeutic antiandrogens (2003) (0)
- Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway (2014) (0)
- Managing metastatic prostate cancer. (2005) (0)
- OC6. Endo180 function in metastatic prostate cancer bone lesions (2008) (0)
- Comprar Molecular Endocrinology of Cancer | Jonathan Waxman | 9780521159494 | Cambridge University Press (2010) (0)
- UK PROSTATE CHARITIES MERGE (2012) (0)
- Cancer and the Law (1999) (0)
- Comprar Cancer Treatment Handbook · The Chemotherapy handbook | Waxman, Jonathan | 9781846289309 | Springer (2009) (0)
- Endocrine‐Responsive Tumors: Prostate Cancer (2009) (0)
- Chapter 1 Biological principles of hormone therapy (2010) (0)
- PO-345 Identification of AR-modulatory microRNAs for prostate cancer progression and therapy (2018) (0)
- Gene ICE as Applied to Studies of Hormonally-Responsive Cancers (2003) (0)
- Japes and jackanapes: on being a junior hospital doctor in the 1970s. (2009) (0)
- MacLeod's Introduction to Medicine (2014) (0)
- The Bed Jape (2014) (0)
- Obligations in emergency room service: protecting the patients and personnel. (1989) (0)
- Top-up fees are not the solution. (2009) (0)
- Fish Ate My Cancer (2012) (0)
- The Grandest Surgeon (2014) (0)
- Should Congress pass a patient-protection law? (1999) (0)
- The Way Home (2014) (0)
- The Driving Offence (2014) (0)
- Abstract 4205: Identification of glycine N-methyltransferase-regulated genes in prostate cancer cells (2012) (0)
- Reforms in the English National Health Service: the voluntary sector in cancer care provision. (2013) (0)
- What is the correct hormonal treatment for prostate cancer? (1993) (0)
- In More Foreign Parts (2014) (0)
- Commentary on the paper entitled 'ICU and 6-month outcome of oncology patients in the intensive care unit.': 'How oncology got better'. (2010) (0)
- Rick’s Big Adventure (2012) (0)
- The Final Examinations (2014) (0)
- The elephant in the room (2012) (0)
- Wnt-11 as a potential target for therapy in prostate cancer (2020) (0)
- Doctors and Cancer: Firewall (2012) (0)
- Christmas Day in the Workhouse (2014) (0)
- Conference With Counsel (2012) (0)
- How Do They Know What I’ve Got? (2012) (0)
- The Joys of Postgraduate Research (2014) (0)
- A circulating miRNA signature to better stratify prostate cancer patients at diagnosis. (2017) (0)
- Inhibiting estrogen responses in breast cancer cells using a fusion protein encoding estrogen receptor-α and the transcriptional repressor PLZF (2005) (0)
- Inhibition of lymphocyte and fibroblast proliferation by local anesthetics (1984) (0)
- Editorial: Interleukin-6: A Multifunctional Molecule in Prostate Cancer (2004) (0)
- Stories About Cancer Patients and their Doctors (2011) (0)
- Re: Ignorance-based cancer treatment (2017) (0)
- Macrophage-mediated breast cancer cell chemotaxis: the role of sphingosine kinase-1 activation (2010) (0)
- Comprar Urological Cancers in Clinical Practice | Waxman, Jonathan | 9781846284649 | Springer (2007) (0)
- The identification of new tumour suppressor micrornas epigenetically silenced in drug resistant cancer cells (2008) (0)
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Jonathan Waxman is affiliated with the following schools:
