Jonathon Pines

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Jonathon Pines is affiliated with the following schools: Institute of Cancer Research, University of Cambridge

Jonathon Pines's AcademicInfluence.com Rankings

Jonathon Pines

Philosophy

#5960

World Rank

#8901

Historical Rank

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#3160

World Rank

#4279

Historical Rank

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Philosophy

Why Is Jonathon Pines Influential?

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According to Wikipedia, Jonathon Noë Joseph Pines is Head of the Cancer Biology Division at the Institute of Cancer Research in London. He was formerly a senior group leader at the Gurdon Institute at the University of Cambridge.

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Jonathon Pines's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2 (1989) (854)
Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport (1991) (847)
Cyclins and cancer (1991) (774)
Progressive activation of CyclinB1-Cdk1 coordinates entry to mitosis. (2010) (728)
Temporal and spatial control of cyclin B1 destruction in metaphase (1999) (714)
Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B (1990) (683)
Active cyclin B1–Cdk1 first appears on centrosomes in prophase (2003) (635)
Cyclins and cyclin-dependent kinases: a biochemical view. (1995) (588)
HDAC4 deacetylase associates with and represses the MEF2 transcription factor (1999) (554)
Cyclins and cyclin-dependent kinases: take your partners. (1993) (450)
Mitotic regulation of the human anaphase‐promoting complex by phosphorylation (2003) (437)
Four-dimensional control of the cell cycle (1999) (406)
Cyclin a Is Destroyed in Prometaphase and Can Delay Chromosome Alignment and Anaphase (2001) (389)
Poly(ADP-ribose)-binding zinc finger motifs in DNA repair/checkpoint proteins (2008) (388)
Ordered proteolysis in anaphase inactivates Plk1 to contribute to proper mitotic exit in human cells (2004) (378)
Human securin proteolysis is controlled by the spindle checkpoint and reveals when the APC/C switches from activation by Cdc20 to Cdh1 (2002) (367)
MPF localization is controlled by nuclear export (1998) (361)
Mitosis : a subject collection from Cold Spring Harbor Perspectives in biology (2015) (333)
Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A (1991) (330)
A cyclin A-protein kinase complex possesses sequence-specific DNA binding activity: p33cdk2 is a component of the E2F-cyclin A complex (1992) (327)
Cyclin/Cdk-Dependent Initiation of DNA Replication in a Human Cell-Free System (1997) (324)
The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction (2008) (315)
Human Cyclin a Is Required for Mitosis until Mid Prophase (1999) (287)
Cubism and the cell cycle: the many faces of the APC/C (2011) (283)
The differential localization of human cyclins A and B is due to a cytoplasmic retention signal in cyclin B. (1994) (282)
Human cyclins B1 and B2 are localized to strikingly different structures: B1 to microtubules, B2 primarily to the Golgi apparatus. (1995) (273)
Mitosis: a matter of getting rid of the right protein at the right time. (2006) (272)
Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal (1999) (272)
Activation of cyclin B1–Cdk1 synchronizes events in the nucleus and the cytoplasm at mitosis (2010) (269)
Okadaic acid, a potent inhibitor of type 1 and type 2A protein phosphatases, activates cdc2/H1 kinase and transiently induces a premature mitosis‐like state in BHK21 cells. (1990) (264)
UBE2S elongates ubiquitin chains on APC/C substrates to promote mitotic exit (2009) (237)
Cytoplasmic accumulation of cyclin B1 in human cells: association with a detergent-resistant compartment and with the centrosome. (1992) (212)
Re-staging mitosis: a contemporary view of mitotic progression (2001) (212)
Molecular cloning and characterization of the mRNA for cyclin from sea urchin eggs. (1987) (204)
Cdc25b and Cdc25c Differ Markedly in Their Properties as Initiators of Mitosis (1999) (192)
Cyclins and cyclin-dependent kinases: theme and variations. (1995) (189)
Loss of RCC1, a nuclear DNA‐binding protein, uncouples the completion of DNA replication from the activation of cdc2 protein kinase and mitosis. (1991) (186)
Cdc20 and Cks direct the spindle checkpoint-independent destruction of cyclin A. (2008) (185)
Cyclins, CDKs and cancer. (1995) (176)
G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2 and cyclin B1/cdc2-kinase complexes differently. (1993) (174)
The Mitotic Checkpoint Complex binds a second CDC20 to inhibit active APC/C (2014) (167)
A PP1/PP2A phosphatase relay controls mitotic progression (2014) (165)
p34cdc2: the S and M kinase? (1990) (160)
An indelible lineage marker for Xenopus using a mutated green fluorescent protein. (1996) (158)
APC15 drives the turnover of MCC-Cdc20 to make the Spindle Assembly Checkpoint responsive to kinetochore attachment (2011) (158)
The cell cycle kinases. (1994) (157)
The ABBA motif binds APC/C activators and is shared by APC/C substrates and regulators. (2015) (154)
Cyclins: wheels within wheels. (1991) (151)
Following cell fate in the living mouse embryo. (1997) (150)
Cyclin A- and cyclin E-Cdk complexes shuttle between the nucleus and the cytoplasm. (2002) (149)
GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes (1998) (146)
The Localization of Human Cyclins B1 and B2 Determines Cdk1 Substrate Specificity and Neither Enzyme Requires Mek to Disassemble the Golgi Apparatus (2001) (145)
The anaphase-promoting complex/cyclosome: APC/C (2006) (143)
Stability, chromatin association and functional activity of mammalian pre‐replication complex proteins during the cell cycle (2001) (142)
Characterization and Expression of Mammalian Cyclin B3, a Prepachytene Meiotic Cyclin* (2002) (139)
Cyclin-dependent kinases: a new cell cycle motif? (1991) (139)
Emi1 is needed to couple DNA replication with mitosis but does not regulate activation of the mitotic APC/C (2007) (139)
Cell cycle: Reaching for a role for the Cks proteins (1996) (137)
Quantitative proteomics reveals the basis for the biochemical specificity of the cell-cycle machinery. (2011) (135)
APC/CCdh1 Targets Aurora Kinase to Control Reorganization of the Mitotic Spindle at Anaphase (2008) (134)
Differential localization of HDAC4 orchestrates muscle differentiation. (2001) (133)
CrkRS: a novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles. (2001) (123)
The anaphase promoting complex/cyclosome is recruited to centromeres by the spindle assembly checkpoint (2004) (120)
Protein kinases and cell cycle control. (1994) (114)
Chfr acts with the p38 stress kinases to block entry to mitosis in mammalian cells (2004) (114)
Cubism and the cell cycle: the many faces of the APC/C (2011) (112)
GFP in mammalian cells. (1995) (111)
Cyclins and the G2/M transition. (1997) (109)
The Spindle Assembly Checkpoint works like a rheostat not a toggle-switch (2013) (106)
Relationships between cdc2 kinase, DNA cross-linking, and cell cycle perturbations induced by nitrogen mustard. (1992) (102)
How APC/C–Cdc20 changes its substrate specificity in mitosis (2011) (99)
Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1 (2003) (98)
Biallelic TRIP13 mutations predispose to Wilms tumor and chromosome missegregation (2017) (97)
How cyclin A destruction escapes the spindle assembly checkpoint (2010) (93)
A quantitative protocol for dynamic measurements of protein interactions by Förster resonance energy transfer-sensitized fluorescence emission (2009) (92)
Centromere tension: a divisive issue (2010) (92)
Cyclins and their associated cyclin-dependent kinases in the human cell cycle. (1993) (89)
Arresting developments in cell-cycle control. (1994) (80)
Proteolysis: anytime, any place, anywhere? (2005) (78)
Cyclins A and B1 in the human cell cycle. (1992) (74)
c-mos proto-oncogene product is partly degraded after release from meiotic arrest and persists during interphase in mouse zygotes. (1991) (74)
Induction of cyclin mRNA and cyclin-associated histone H1 kinase during liver regeneration. (1992) (73)
Mad2 and the APC/C compete for the same site on Cdc20 to ensure proper chromosome segregation (2012) (72)
p21 inhibits cyclin shock (1994) (69)
Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C–Cdc20 complex (2013) (69)
Spindle assembly checkpoint activation and silencing at kinetochores (2021) (65)
Requirement for p34cdc2 kinase is restricted to mitosis in the mammalian cdc2 mutant FT210 (1992) (63)
Cyclin B1 is essential for mitosis in mouse embryos, and its nuclear export sets the time for mitosis (2018) (59)
Cell cycle: Checkpoint on the nuclear frontier (1999) (57)
E2F transcription factor is a target for the RB protein and the cyclin A protein. (1991) (53)
The Mitotic Checkpoint Complex Requires an Evolutionary Conserved Cassette to Bind and Inhibit Active APC/C (2016) (46)
The biochemistry of mitosis. (2015) (42)
UbcH10 has a rate-limiting role in G1 phase but might not act in the spindle checkpoint or as part of an autonomous oscillator (2008) (42)
Torin1-mediated TOR kinase inhibition reduces Wee1 levels and advances mitotic commitment in fission yeast and HeLa cells (2014) (41)
Cell proliferation and control (1992) (40)
Cyclin from sea urchins to HeLas: making the human cell cycle. (1996) (36)
Human Mob1 proteins are required for cytokinesis by controlling microtubule stability (2012) (35)
Defining the role of Emi1 in the DNA replication–segregation cycle (2008) (32)
Cyclin-dependent kinase inhibitors: the age of crystals. (1997) (32)
Cell to cell contact and extracellular matrix. (1998) (25)
Human cell division: the involvement of cyclins A and B1, and multiple cdc2s. (1991) (25)
Localization of cell cycle regulators by immunofluorescence. (1997) (25)
Confirmational change (1995) (24)
Cyclin B1-Cdk1 facilitates MAD1 release from the nuclear pore to ensure a robust spindle checkpoint (2020) (23)
Evidence for how APC-C-Cdc20 changes its substrate specificity in mitosis (2010) (21)
A single cyclin A gene and multiple cyclin B1-related sequences are dispersed in the mouse genome. (1992) (20)
Use of Green Fluorescent Protein in mouse embryos. (2001) (19)
The Renaissance or the cuckoo clock (2011) (19)
Ubiquitin with everything (1994) (19)
Clear as crystal? (1993) (19)
Regulation of the G2 to M transition. (1998) (16)
The APC/C: a smörgåsbord for proteolysis. (2009) (13)
Image integrity and standards (2020) (13)
The centrosome opens the way to mitosis. (2007) (12)
Cell cycle. p21 inhibits cyclin shock. (1994) (10)
Delayed APC/C activation extends the first mitosis of mouse embryos (2017) (9)
Getting In and Out of Mitosis (2008) (8)
Molecular cloning andcharacterization ofthemRNA forcyclin fromseaurchin eggs (1987) (8)
Co-activator independent differences in how the metaphase and anaphase APC/C recognise the same substrate (2014) (8)
Cell cycle. Confirmational change. (1995) (7)
The Securities and Exchange Commission and Accounting Principles (1965) (5)
Assays for CDK Activity and DNA Replication in the Cell Cycle (1998) (5)
Cyclin B1-Cdk1 binding to MAD1 links nuclear pore disassembly to chromosomal stability (2019) (4)
Escaping the firing squad: acetylation of BubR1 protects it from degradation in checkpoint cells (2009) (4)
Cell cycle trials in Salamanca (2002) (4)
Assays for the spindle assembly checkpoint in cell culture. (2018) (3)
Cytoskeleton. Web alert. (1998) (2)
Cell cycle trials in Salamanca: workshop on G2/M progression and associated checkpoints. (2002) (2)
fluorescence emission interactions by Förster resonance energy transfer-sensitized A quantitative protocol for dynamic measurements of protein Supplementary data (2009) (2)
Workshop on G 2 /M progression and associated checkpoints (2002) (1)
Cell Lineage Analysis (2000) (1)
Cell cycle — Materials and methods Edited by Michele Pagano, Springer-Verlag, 1995. DM128.00 (xxx + 285 pages) ISBN 3 540 58066 2 (1996) (1)
Cell cycle. Ubiquitin with everything. (1994) (1)
Requirement for p 34 cd 2 Kinase Is Restricted to Mitosis in the Mammalian cdc 2 Mutant FT 210 (2002) (1)
Green Fluorescent Protein. Methods in Enzymology, Vol. 302; Edited by P.M. Conn, Academic Press; San Diego, 1999. xxxii+490 pp. $ 99.95 (hb). ISBN 0‐121‐82203‐6 (1999) (1)
Web alert: Cell-to-cell contact and extracellular matrix. (1997) (1)
Cell multiplicationWeb alert (1999) (1)
Cell cycle-dependent binding between Cyclin B1 and Cdk1 revealed by time-resolved fluorescence correlation spectroscopy (2022) (1)
Cell lineage analysis. Applications of green fluorescent protein. (2000) (1)
Open Biology Editorial: What do you really think? (2020) (1)
A red light in mitosis (2012) (1)
Every good biologist deserves favour (2023) (0)
Faculty Opinions recommendation of Requirements of cyclin a for mitosis are independent of its subcellular localization. (2004) (0)
Method for determination of the cell cycle position (2002) (0)
The Localisation of Human Cyclins and CDKS in the Cell Cycle (1994) (0)
A conserved mechanism to maintain the spindle checkpoint: Cdc20 switches from an APC/C activator to a substrate (2008) (0)
The newly resolved crystal structure of CDK2 gives us a tantalizing glimpse of the mechanisms underlying the regulation of cyclin-dependent kinases by cyclins and by phosphorylation. (1993) (0)
New approaches to research on mitosis (2006) (0)
Cell division, growth and death. Cell growth: live and let die. (2003) (0)
Cell-to-cell contact and extracellular matrix. Web Alert. (1999) (0)
Faculty Opinions recommendation of Polo-like kinase-1 is required for bipolar spindle formation but is dispensable for anaphase promoting complex/Cdc20 activation and initiation of cytokinesis. (2004) (0)
Catalytic antibodies: perusing combinatorial libraries (1994) (0)
Faculty Opinions recommendation of Midbody and primary cilium of neural progenitors release extracellular membrane particles enriched in the stem cell marker prominin-1. (2007) (0)
Nucleus and gene expression. (2000) (0)
Table of Contents (1995) (0)
Cell regulation. Web alert. (1998) (0)
Decision letter: The GNU subunit of PNG kinase, the developmental regulator of mRNA translation, binds BIC-C to localize to RNP granules (2021) (0)
Membrane permeability. Membranes and sorting. (2000) (0)
Cell differentiation. Cell multiplication. Web alert. (1998) (0)
Faculty Opinions recommendation of Addition of a photocrosslinking amino acid to the genetic code of Escherichiacoli. (2002) (0)
Web alert. Cell differentiation cell multiplication. (1999) (0)
Reviewers in 2019 (2020) (0)
Web alert. Cell regulation. (1997) (0)
Meeting Report: International Symposium on Ran and the Cell Cycle, October 2–5, 2005, Awaji Yumebutai, Japan (2006) (0)
Faculty Opinions recommendation of A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs. (2005) (0)
Faculty Opinions recommendation of Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells. (2008) (0)
Thedifferential localization ofhumancyclins A and Bisduetoa cytoplasmic retention signal incyclin B (1994) (0)
Faculty Opinions recommendation of Fast complementation of split fluorescent protein triggered by DNA hybridization. (2006) (0)
Membrane permeability. Membranes and sorting. Web alert. (1998) (0)
Web alert Cell multiplication Cell differentiation (1997) (0)
Delayed APC/C activation extends the first mitosis of mouse embryos (2017) (0)
The cell cycle: back to basics (1996) (0)
making the human cell cycle (1995) (0)
HORMAD1 drives spindle assembly checkpoint defects and sensitivity to multiple mitotic kinases (2022) (0)
Web alert. Cell regulation. (1997) (0)
Rising to the challenge (2021) (0)
Research Capsule Cyclins : Wheels within Wheels (2005) (0)
One con The Renaissance or the cuckoo clock (2011) (0)
Reviewers in 2022 (2023) (0)
Reviewers in 2020 (2021) (0)
Web alert. Nucleus and gene expression. (1997) (0)
Every good biologist deserves favour (2023) (0)
Reviewers in 2021 (2022) (0)
Faculty Opinions recommendation of Emi1-mediated M-phase arrest in Xenopus eggs is distinct from cytostatic factor arrest. (2004) (0)
Web alert. Cell differentiation and cell multiplication. (1999) (0)
Decision letter: The copy-number and varied strengths of MELT motifs in Spc105 balance the strength and responsiveness of the spindle assembly checkpoint (2020) (0)
Nucleus and gene expression. Web alert. (1999) (0)
Cell differentiation and Cell multiplication (2001) (0)
Faculty Opinions recommendation of BubR1 acetylation at prometaphase is required for modulating APC/C activity and timing of mitosis. (2009) (0)

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What Schools Are Affiliated With Jonathon Pines?

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Jonathon Pines's Academic­Influence.com Rankings