José-Alain Sahel
French ophthalmologist
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Why Is José-Alain Sahel Influential?
(Suggest an Edit or Addition)According to Wikipedia, José-Alain Sahel is a French ophthalmologist and scientist. He is currently the chair of the Department of Ophthalmology at the University of Pittsburgh School of Medicine, director of the UPMC Eye Center, and the Eye and Ear Foundation Chair of Ophthalmology. Dr. Sahel previously led the Vision Institute in Paris, a research center associated with the one of the oldest eye hospitals of Europe - Quinze-Vingts National Eye Hospital in Paris, founded in 1260. He is a pioneer in the field of artificial retina and eye regenerative therapies. He is a member of the French Academy of Sciences.
José-Alain Sahel's Published Works
Published Works
- A large genome-wide association study of age-related macular degeneration highlights contributions of rare and common variants (2015) (1024)
- Seven New Loci Associated with Age-Related Macular Degeneration (2013) (741)
- Interim results from the international trial of Second Sight's visual prosthesis. (2012) (603)
- Genetic Reactivation of Cone Photoreceptors Restores Visual Responses in Retinitis Pigmentosa (2010) (586)
- Identification and characterization of rod-derived cone viability factor (2004) (422)
- The Argus II epiretinal prosthesis system allows letter and word reading and long-term function in patients with profound vision loss (2013) (318)
- Rod-Derived Cone Viability Factor Promotes Cone Survival by Stimulating Aerobic Glycolysis (2015) (291)
- Five-Year Safety and Performance Results from the Argus II Retinal Prosthesis System Clinical Trial. (2016) (272)
- Prevalence of Age-Related Macular Degeneration in Europe (2017) (255)
- Retinitis pigmentosa: rod photoreceptor rescue by a calcium-channel blocker in the rd mouse (1999) (245)
- Long-Term Results from an Epiretinal Prosthesis to Restore Sight to the Blind. (2015) (227)
- CCR2+ monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice (2013) (226)
- [Retinal repair by transplantation of photoreceptor precursors]. (2007) (226)
- From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium (2014) (225)
- TRPM1 is mutated in patients with autosomal-recessive complete congenital stationary night blindness. (2009) (223)
- Endoscopic transpapillary drainage of pancreatic pseudocysts. (1995) (218)
- Optogenetic therapy for retinitis pigmentosa (2011) (214)
- Optimized allotopic expression of the human mitochondrial ND4 prevents blindness in a rat model of mitochondrial dysfunction. (2008) (213)
- Pancreas Divisum is a Probable Cause of Acute Pancreatitis: A Report of 137 Cases (1990) (208)
- Normal retina releases a diffusible factor stimulating cone survival in the retinal degeneration mouse. (1998) (207)
- Partial recovery of visual function in a blind patient after optogenetic therapy (2021) (198)
- Foveal shape and structure in a normal population. (2011) (187)
- The Detection of Motion by Blind Subjects With the Epiretinal 60-Electrode (Argus II) Retinal Prosthesis. (2013) (181)
- Effect of autologous platelet concentrate in surgery for idiopathic macular hole: results of a multicenter, double-masked, randomized trial. Platelets in Macular Hole Surgery Group. (1999) (181)
- Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice. (2000) (173)
- NMNAT1 mutations cause Leber congenital amaurosis (2012) (172)
- Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV Restores ON and OFF visual responses in blind mice. (2015) (167)
- Development and application of a next-generation-sequencing (NGS) approach to detect known and novel gene defects underlying retinal diseases (2012) (166)
- Emerging therapies for inherited retinal degeneration (2016) (166)
- Functional cone rescue by RdCVF protein in a dominant model of retinitis pigmentosa. (2009) (164)
- Case-control study of the risk factors for age related macular degeneration (1998) (160)
- Endoscopic Cystoduodenostomy of Cysts of Chronic Calcifying Pancreatitis: A Report of 20 Cases (1987) (160)
- Human Usher 1B/mouse shaker-1: the retinal phenotype discrepancy explained by the presence/absence of myosin VIIA in the photoreceptor cells. (1996) (158)
- Management of cysts and pseudocysts complicating chronic pancreatitis. A retrospective study of 143 patients. (1993) (155)
- Clinical characteristics and current therapies for inherited retinal degenerations. (2015) (155)
- Chronic pancreatitis and inflammatory bowel disease: true or coincidental association? (1999) (154)
- Selective transplantation of rods delays cone loss in a retinitis pigmentosa model. (2000) (151)
- CRB1 mutations in inherited retinal dystrophies (2012) (150)
- Localization of Usher 1 proteins to the photoreceptor calyceal processes, which are absent from mice (2012) (150)
- Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human iPS Cells in Xeno‐Free and Feeder‐Free Conditions (2017) (148)
- Targeted inactivation of dystrophin gene product Dp71: phenotypic impact in mouse retina. (2003) (147)
- Gene therapy for blindness. (2013) (138)
- Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration. (2015) (137)
- Natural History of Geographic Atrophy Progression Secondary to Age-Related Macular Degeneration (Geographic Atrophy Progression Study). (2016) (135)
- Ocular tissue imaging using ultrahigh-resolution, full-field optical coherence tomography. (2004) (135)
- Inherited Retinal Degenerations: Current Landscape and Knowledge Gaps (2018) (134)
- Survival of Purified Rat Photoreceptors In Vitro Is Stimulated Directly by Fibroblast Growth Factor-2 (1998) (134)
- Long-term results of endoscopic management of pancreas divisum with recurrent acute pancreatitis. (2002) (132)
- Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina (2016) (132)
- Rod-Derived Cone Viability Factor for Treating Blinding Diseases: From Clinic to Redox Signaling (2010) (129)
- Results of proton therapy of uveal melanomas treated in Nice. (1999) (129)
- Microglial changes occur without neural cell death in diabetic retinopathy (2007) (128)
- Anxiety and depression prevalence rates in age-related macular degeneration. (2007) (124)
- Mutations in IFT172 cause isolated retinal degeneration and Bardet-Biedl syndrome. (2015) (124)
- Inherited retinal degenerations: therapeutic prospects. (2004) (122)
- The Natural History of the Progression of Atrophy Secondary to Stargardt Disease (ProgStar) Studies: Design and Baseline Characteristics: ProgStar Report No. 1. (2016) (120)
- Phototoxic Action Spectrum on a Retinal Pigment Epithelium Model of Age-Related Macular Degeneration Exposed to Sunlight Normalized Conditions (2013) (120)
- Biliary stenting in benign biliary stenosis complicating chronic calcifying pancreatitis. (1993) (119)
- Whole-exome sequencing identifies LRIT3 mutations as a cause of autosomal-recessive complete congenital stationary night blindness. (2013) (117)
- Photovoltaic Restoration of Central Vision in Atrophic Age-Related Macular Degeneration. (2020) (114)
- Whole-exome sequencing identifies mutations in GPR179 leading to autosomal-recessive complete congenital stationary night blindness. (2012) (114)
- Selective excitotoxic degeneration of adult pig retinal ganglion cells in vitro. (2001) (112)
- Panretinal, high-resolution color photography of the mouse fundus. (2007) (112)
- In vivo anterior segment imaging in the rat eye with high speed white light full-field optical coherence tomography. (2005) (111)
- A New Promoter Allows Optogenetic Vision Restoration with Enhanced Sensitivity in Macaque Retina. (2017) (109)
- Mucinous Ductal Ectasia of the Pancreas: A Premalignant Disease and a Cause of Obstructive Pancreatitis (1991) (109)
- Let There Be Light: Gene and Cell Therapy for Blindness. (2016) (108)
- Protein content of precipitates present in pancreatic juice of alcoholic subjects and patients with chronic calcifying pancreatitis. (1983) (107)
- Taurine deficiency is a cause of vigabatrin‐induced retinal phototoxicity (2009) (105)
- Complement Factor H Inhibits CD47‐Mediated Resolution of Inflammation (2017) (105)
- Complete exon sequencing of all known Usher syndrome genes greatly improves molecular diagnosis (2011) (104)
- The glutamate transporter EAAT5 works as a presynaptic receptor in mouse rod bipolar cells (2006) (104)
- Morphometric analysis of small arteries in the human retina using adaptive optics imaging: relationship with blood pressure and focal vascular changes (2014) (104)
- Photoreceptor transplants increase host cone survival in the retinal degeneration (rd) mouse. (1997) (102)
- On phagocytes and macular degeneration (2017) (102)
- Apolipoprotein E promotes subretinal mononuclear phagocyte survival and chronic inflammation in age-related macular degeneration (2015) (101)
- Identification of gene expression changes associated with the progression of retinal degeneration in the rd1 mouse. (2004) (100)
- Whipple's disease: immunospecific and quantitative immunohistochemical study of intestinal biopsy specimens. (2003) (99)
- Temporal properties of visual perception on electrical stimulation of the retina. (2012) (96)
- The optimized allotopic expression of ND1 or ND4 genes restores respiratory chain complex I activity in fibroblasts harboring mutations in these genes. (2008) (96)
- High resolution fundus imaging by confocal scanning laser ophthalmoscopy in the mouse (2006) (94)
- Bilateral visual improvement with unilateral gene therapy injection for Leber hereditary optic neuropathy (2020) (92)
- Characterization and Transplantation of CD73-Positive Photoreceptors Isolated from Human iPSC-Derived Retinal Organoids (2018) (91)
- Kir4.1 and AQP4 associate with Dp71‐ and utrophin‐DAPs complexes in specific and defined microdomains of Müller retinal glial cell membrane (2008) (91)
- RETINAL INNER NUCLEAR LAYER MICROCYSTIC CHANGES IN OPTIC NERVE ATROPHY: A Novel Spectral-Domain OCT Finding (2013) (91)
- Spectral-Domain Optical Coherence Tomography of the Rodent Eye: Highlighting Layers of the Outer Retina Using Signal Averaging and Comparison with Histology (2014) (90)
- Taurine: The comeback of a neutraceutical in the prevention of retinal degenerations (2014) (90)
- Restoring vision (2018) (89)
- Pathology of chronic calcifying pancreatitis. (1976) (89)
- Rod–Cone Interactions: Developmental and Clinical Significance (2001) (88)
- Cholestasis and lesions of the biliary tract in chronic pancreatitis. (1978) (88)
- Endoscopic drainage of pancreatic cysts. (1991) (87)
- EYS is a major gene for rod‐cone dystrophies in France (2010) (87)
- Retinitis pigmentosa and other dystrophies. (2010) (86)
- Optical coherence tomography findings in tamoxifen retinopathy. (2005) (86)
- Noninvasive gene delivery to foveal cones for vision restoration. (2018) (86)
- Endoscopic ultrasonographic diagnosis of pancreatic cancer complicating chronic pancreatitis. (1996) (84)
- Allotopic mRNA localization to the mitochondrial surface rescues respiratory chain defects in fibroblasts harboring mitochondrial DNA mutations affecting complex I or v subunits. (2007) (84)
- Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice. (2002) (82)
- Evidence for glutamate-mediated excitotoxic mechanisms during photoreceptor degeneration in the rd1 mouse retina. (2005) (80)
- Ocular manifestations in the inherited DNA repair disorders. (2003) (80)
- Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3. (2012) (79)
- Quality Versus Quantity: Assessing Individual Research Performance (2011) (79)
- Adaptive optics imaging of geographic atrophy. (2013) (79)
- Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization (2015) (79)
- An innovative strategy for the molecular diagnosis of Usher syndrome identifies causal biallelic mutations in 93% of European patients (2016) (77)
- The disruption of the rod-derived cone viability gene leads to photoreceptor dysfunction and susceptibility to oxidative stress (2010) (77)
- GABAA and GABAC receptors in adult porcine cones: evidence from a photoreceptor‐glia co‐culture model (1998) (77)
- Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells (2018) (77)
- Metabolic and redox signaling in the retina (2016) (76)
- Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration (2015) (75)
- Channel-forming leucotoxins from Staphylococcus aureus cause severe inflammatory reactions in a rabbit eye model. (1997) (75)
- Restoration of visual function by transplantation of optogenetically engineered photoreceptors (2018) (75)
- mRNA localization to the mitochondrial surface allows the efficient translocation inside the organelle of a nuclear recoded ATP6 protein. (2006) (74)
- Safety of rAAV2/2-ND4 Gene Therapy for Leber Hereditary Optic Neuropathy. (2018) (74)
- In vivo high resolution human corneal imaging using full-field optical coherence tomography. (2018) (73)
- Human ESC–derived retinal epithelial cell sheets potentiate rescue of photoreceptor cell loss in rats with retinal degeneration (2017) (73)
- GABAC Receptors Are Localized with Microtubule-Associated Protein 1B in Mammalian Cone Photoreceptors (2000) (72)
- The implications of rod-dependent cone survival for basic and clinical research. (1999) (71)
- Increased High-Density Lipoprotein Levels Associated with Age-Related Macular Degeneration: Evidence from the EYE-RISK and European Eye Epidemiology Consortia. (2018) (71)
- Microvascular remodeling after occlusion-recanalization of a branch retinal vein in rats. (2004) (71)
- Performance of real‐world functional vision tasks by blind subjects improves after implantation with the Argus® II retinal prosthesis system (2016) (71)
- Taurine Provides Neuroprotection against Retinal Ganglion Cell Degeneration (2012) (71)
- Foveal damage in habitual poppers users. (2011) (71)
- Characterization of the intermolecular associations of the dystrophin-associated glycoprotein complex in retinal Müller glial cells. (2000) (70)
- Functional ultrasound imaging of the brain reveals propagation of task-related brain activity in behaving primates (2019) (70)
- Alternate FGF2-ERK1/2 Signaling Pathways in Retinal Photoreceptor and Glial Cells in Vitro * (2001) (70)
- Mucinous pancreatic duct ectasia in the body of the pancreas. (1989) (70)
- Next-generation sequencing applied to a large French cone and cone-rod dystrophy cohort: mutation spectrum and new genotype-phenotype correlation (2015) (69)
- Ocular inflammation induces trigeminal pain, peripheral and central neuroinflammatory mechanisms (2016) (69)
- Case-control study of the risk factors for age related macular degeneration. France-DMLA Study Group. (1998) (69)
- Rod-derived Cone Viability Factor-2 is a novel bifunctional-thioredoxin-like protein with therapeutic potential (2007) (68)
- Repair of Rhodopsin mRNA by Spliceosome-Mediated RNA Trans-Splicing: A New Approach for Autosomal Dominant Retinitis Pigmentosa (2015) (66)
- Partial characterization of retina-derived cone neuroprotection in two culture models of photoreceptor degeneration. (2003) (66)
- APOE Isoforms Control Pathogenic Subretinal Inflammation in Age-Related Macular Degeneration (2015) (65)
- Clinico-pathological conditions associated with pancreas divisum. (1982) (64)
- Retinal-cell-conditioned medium prevents TNF-alpha-induced apoptosis of purified ganglion cells. (2005) (63)
- Subretinal mononuclear phagocytes induce cone segment loss via IL-1β (2016) (63)
- Rods in daylight act as relay cells for cone-driven horizontal cell–mediated surround inhibition (2014) (63)
- Mutations in IMPG1 cause vitelliform macular dystrophies. (2013) (62)
- En Face OCT Imaging for the Diagnosis of Outer Retinal Tubulations in Age-Related Macular Degeneration (2012) (62)
- Polyelectrolyte multilayer films as substrates for photoreceptor cells. (2006) (62)
- Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss (2015) (62)
- IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis (2020) (61)
- Endoscopic treatment of chronic pancreatitis. (2007) (61)
- Intraocular pressure reduction and neuroprotection conferred by bone marrow-derived mesenchymal stem cells in an animal model of glaucoma (2015) (61)
- Gene therapy for inherited retinal degenerations. (2014) (60)
- Taurine deficiency damages photoreceptors and retinal ganglion cells in vigabatrin-treated neonatal rats (2010) (60)
- Poppers-associated retinal toxicity. (2010) (60)
- Visual Acuity Loss and Associated Risk Factors in the Retrospective Progression of Stargardt Disease Study (ProgStar Report No. 2). (2016) (59)
- Immune Response and Intraocular Inflammation in Patients With Leber Hereditary Optic Neuropathy Treated With Intravitreal Injection of Recombinant Adeno-Associated Virus 2 Carrying the ND4 Gene: A Secondary Analysis of a Phase 1/2 Clinical Trial (2019) (58)
- Efficacy and Safety of Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy Treated within 6 Months of Disease Onset. (2021) (58)
- Percutaneous treatment of hydatid cysts under sonographic guidance (1994) (57)
- Three-dimensional electrode arrays for retinal prostheses: modeling, geometry optimization and experimental validation (2011) (56)
- The Thioredoxin-like Protein Rod-derived Cone Viability Factor (RdCVFL) Interacts with TAU and Inhibits Its Phosphorylation in the Retina* (2009) (56)
- Systemic and Ocular Determinants of Peripapillary Retinal Nerve Fiber Layer Thickness Measurements in the European Eye Epidemiology (E3) Population. (2018) (55)
- Rhodopsin maturation defects induce photoreceptor death by apoptosis: a fly model for RhodopsinPro23His human retinitis pigmentosa. (2005) (55)
- Brain-derived neurotrophic factor signalling in adult pig retinal ganglion cell neurite regeneration in vitro (2004) (55)
- Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration. (2014) (55)
- Intraductal papillary or mucinous tumors (IPMT) of the pancreas: Report of a case series and review of the literature (2001) (55)
- 3D functional ultrasound imaging of the cerebral visual system in rodents (2017) (54)
- The aging of the retina (2003) (54)
- Insight into the mechanisms of enhanced retinal transduction by the engineered AAV2 capsid variant ‐7m8 (2016) (54)
- Ophthalmology Practice During the Coronavirus Disease 2019 Pandemic: The University of Pittsburgh Experience in Promoting Clinic Safety and Embracing Video Visits (2020) (53)
- Pixium Vision: First Clinical Results and Innovative Developments (2017) (53)
- mRNA trans‐splicing in gene therapy for genetic diseases (2016) (53)
- Relative Frequencies of Inherited Retinal Dystrophies and Optic Neuropathies in Southern France: Assessment of 21-year Data Management (2013) (53)
- Genetic pleiotropy between age-related macular degeneration and 16 complex diseases and traits (2017) (53)
- Neuroglobin involvement in respiratory chain function and retinal ganglion cell integrity. (2012) (52)
- Growth factors and gangliosides as neuroprotective agents in excitotoxicity and ischemia. (1998) (52)
- Excessive activation of cyclic nucleotide‐gated channels contributes to neuronal degeneration of photoreceptors (2005) (52)
- 3D shaped mechanically flexible diamond microelectrode arrays for eye implant applications: The MEDINAS project (2011) (52)
- ["Melanoma 92". epidemiological study of uveal melanoma in France]. (1995) (52)
- Rod-cone interdependence: implications for therapy of photoreceptor cell diseases. (2001) (52)
- Advanced glycation end products can induce glial reaction and neuronal degeneration in retinal explants (2005) (51)
- [Detection, monitoring and treatment of diabetic retinopathy. Recommendations of ALFEDIAM. Committee of above-mentioned experts and validated by the board of directors and scientific board of ALFEDIAM]. (1996) (51)
- Villous adenoma of the main pancreatic duct: a potentially malignant tumor? (1990) (51)
- Distribution of vesicular glutamate transporters in rat and human retina (2006) (50)
- A review of in vivo animal studies in retinal prosthesis research (2008) (50)
- An analysis of observer‐rated functional vision in patients implanted with the Argus II Retinal Prosthesis System at three years (2016) (50)
- Ophthalmology Practice During the Coronavirus Disease 2019 Pandemic: The University of Pittsburgh Experience in Promoting Clinic Safety and Embracing Video Visits. (2020) (50)
- Taurine deficiency damages retinal neurones: cone photoreceptors and retinal ganglion cells (2011) (50)
- Synthetic 3D diamond-based electrodes for flexible retinal neuroprostheses: Model, production and in vivo biocompatibility. (2015) (50)
- Neural stimulation for visual rehabilitation: Advances and challenges (2013) (49)
- Usher syndrome type 1–associated cadherins shape the photoreceptor outer segment (2017) (49)
- Survival and regeneration of adult human and other mammalian photoreceptors in culture. (1996) (49)
- Voltage-gated channels and calcium homeostasis in mammalian rod photoreceptors. (2005) (49)
- Hypoglycemia induces general neuronal death, whereas hypoxia and glutamate transport blockade lead to selective retinal ganglion cell death in vitro. (2001) (49)
- Late histological and functional changes in the P23H rat retina after photoreceptor loss (2010) (49)
- Lrit3 Deficient Mouse (nob6): A Novel Model of Complete Congenital Stationary Night Blindness (cCSNB) (2014) (48)
- The primate model for understanding and restoring vision (2019) (48)
- Whole-exome sequencing identifies KIZ as a ciliary gene associated with autosomal-recessive rod-cone dystrophy. (2014) (48)
- Microcystic Changes in the Retinal Internal Nuclear Layer Associated with Optic Atrophy: A Prospective Study (2014) (47)
- Genotyping microarray for CSNB-associated genes. (2009) (47)
- Real-time polymerase chain reaction and intraocular antibody production for the diagnosis of viral versus toxoplasmic infectious posterior uveitis (2011) (47)
- The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina. (2010) (47)
- Gene therapy for mitochondrial diseases: Leber Hereditary Optic Neuropathy as the first candidate for a clinical trial. (2014) (47)
- Biallelic Mutations in GNB3 Cause a Unique Form of Autosomal-Recessive Congenital Stationary Night Blindness. (2016) (47)
- Filtering genes to improve sensitivity in oligonucleotide microarray data analysis (2007) (46)
- Prevalence and novelty of PRPF31 mutations in French autosomal dominant rod-cone dystrophy patients and a review of published reports (2010) (46)
- Vigabatrin, the GABA‐transaminase inhibitor, damages cone photoreceptors in rats (2004) (46)
- Role of hyaluronidase in diplopia after peribulbar anesthesia for cataract surgery. (2005) (46)
- Cleavage of Mer Tyrosine Kinase (MerTK) from the Cell Surface Contributes to the Regulation of Retinal Phagocytosis* (2014) (45)
- Spectrum of rhodopsin mutations in French autosomal dominant rod-cone dystrophy patients. (2010) (45)
- Malignant transformation of an iris melanocytoma (1989) (45)
- Behavioural responses to a photovoltaic subretinal prosthesis implanted in non-human primates (2019) (45)
- Transcriptomic Analysis of Human Retinal Detachment Reveals Both Inflammatory Response and Photoreceptor Death (2011) (44)
- LRIT3 is essential to localize TRPM1 to the dendritic tips of depolarizing bipolar cells and may play a role in cone synapse formation (2015) (44)
- Artificial retina: the multichannel processing of the mammalian retina achieved with a neuromorphic asynchronous light acquisition device (2012) (44)
- Combined 3DISCO clearing method, retrograde tracer and ultramicroscopy to map corneal neurons in a whole adult mouse trigeminal ganglion. (2015) (44)
- Ability of retinal Müller glial cells to protect neurons against excitotoxicity in vitro depends upon maturation and neuron‐glial interactions (1999) (44)
- Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina (2002) (44)
- AAV‐mediated gene delivery in Dp71‐null mouse model with compromised barriers (2014) (44)
- Does GDNF exert its neuroprotective effects on photoreceptors in the rd1 retina through the glial glutamate transporter GLAST? (2005) (44)
- Expression of Dp71 in Müller glial cells: a comparison with utrophin- and dystrophin-associated proteins. (2000) (43)
- Importance of eye position on spatial localization in blind subjects wearing an Argus II retinal prosthesis. (2014) (43)
- Impact of Retinitis Pigmentosa on Quality of Life, Mental Health, and Employment Among Young Adults. (2017) (43)
- Downregulation of apoptosis-inducing factor in Harlequin mice induces progressive and severe optic atrophy which is durably prevented by AAV2-AIF1 gene therapy. (2012) (42)
- Genotypic and Phenotypic Characterization of P23H Line 1 Rat Model (2015) (42)
- Differential Distribution of the Members of the Dystrophin Glycoprotein Complex in Mouse Retina: Effect of the mdx3Cv Mutation (2001) (42)
- In vivo observation of the locomotion of microglial cells in the retina (2010) (42)
- Saving cone cells in hereditary rod diseases: a possible role for rod-derived cone viability factor (RdCVF) therapy. (2005) (41)
- Early and late stage gene therapy interventions for inherited retinal degenerations (2021) (41)
- GOAnno: GO annotation based on multiple alignment (2005) (41)
- Basic fibroblast and epidermal growth factors stimulate survival in adult porcine photoreceptor cell cultures. (2003) (41)
- Visual Acuity Change over 12 Months in the Prospective Progression of Atrophy Secondary to Stargardt Disease (ProgStar) Study: ProgStar Report Number 6. (2017) (41)
- Multicenter Pathological Study of Chronic Pancreatitis. Morphological Regional Variations and Differences Between Chronic Calcifying Pancreatitis and Obstructive Pancreatitis (1986) (41)
- Gene therapy in ophthalmology: validation on cultured retinal cells and explants from postmortem human eyes. (2011) (41)
- Modifications of pure human pancreatic juice induced by chronic alcohol consumption (1979) (40)
- Optogenetic therapy: high spatiotemporal resolution and pattern discrimination compatible with vision restoration in non-human primates (2021) (40)
- Optogenetic Light Sensors in Human Retinal Organoids (2018) (40)
- Melanoma arising de novo over a 16-month period. (1988) (40)
- Treatment of epilepsy: the GABA‐transaminase inhibitor, vigabatrin, induces neuronal plasticity in the mouse retina (2008) (40)
- Dynamic full-field optical coherence tomography: 3D live-imaging of retinal organoids (2019) (40)
- Subretinal electrode implantation in the P23H rat for chronic stimulations (2006) (39)
- Advancing Clinical Trials for Inherited Retinal Diseases: Recommendations from the Second Monaciano Symposium (2020) (39)
- Transplantation of Photoreceptor and Total Neural Retina Preserves Cone Function in P23H Rhodopsin Transgenic Rat (2010) (39)
- Distinctive Glial and Neuronal Interfacing on Nanocrystalline Diamond (2014) (39)
- Nonparallel secretion of enzymes in human duodenal juice and pure pancreatic juice collected by endoscopic retrograde catheterization of the papilla. (1977) (38)
- VEGF is an autocrine/paracrine neuroprotective factor for injured retinal ganglion neurons (2020) (38)
- Health-related quality of life and utility in patients with age-related macular degeneration. (2007) (38)
- Ptf1a/Rbpj complex inhibits ganglion cell fate and drives the specification of all horizontal cell subtypes in the chick retina. (2011) (38)
- Topography of Patchy Retinal Whitening during Acute Perfused Retinal Vein Occlusion by Optical Coherence Tomography and Adaptive Optics Fundus Imaging (2011) (38)
- Retinal and choroidal changes observed with ‘En face’ enhanced-depth imaging OCT in central serous chorioretinopathy (2013) (38)
- Differential Proteomic Analysis of the Mouse Retina (2003) (37)
- Mammalian retinal horizontal cells are unconventional GABAergic neurons (2011) (37)
- Adult human retinal neurons in culture: Physiology of horizontal cells. (1998) (37)
- Test–Retest Variability of Functional and Structural Parameters in Patients with Stargardt Disease Participating in the SAR422459 Gene Therapy Trial (2016) (37)
- Retinal prostheses: clinical results and future challenges. (2014) (37)
- Survival and regeneration of adult human photoreceptors in vitro (1994) (37)
- Functional ultrasound imaging of deep visual cortex in awake nonhuman primates (2020) (36)
- In vivo high resolution human retinal imaging with wavefront correctionless full-field OCT (2018) (36)
- Imaging of macroaneurysms occurring during retinal vein occlusion and diabetic retinopathy by indocyanine green angiography and high resolution optical coherence tomography (2010) (36)
- Genotypic influences on severity of exudative age-related macular degeneration. (2010) (36)
- P 351 Monosialoganglioside GM1 reduces ischemia-reperfusion induced injury in the rat retina (1995) (36)
- Increased functional connectivity between language and visually deprived areas in late and partial blindness (2016) (36)
- Functional Implication of Dp71 in Osmoregulation and Vascular Permeability of the Retina (2009) (36)
- The Thioredoxin Encoded by the Rod-Derived Cone Viability Factor Gene Protects Cone Photoreceptors Against Oxidative Stress. (2016) (36)
- Fibroblast growth factor receptor (FGFR) and candidate signaling molecule distribution within rat and human retina. (2002) (36)
- Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF‐α (2016) (35)
- The 10q26 Risk Haplotype of Age-Related Macular Degeneration Aggravates Subretinal Inflammation by Impairing Monocyte Elimination. (2020) (35)
- MERTK mutation update in inherited retinal diseases (2018) (35)
- A case of primary non-Hodgkin lymphoma of the pancreas. (1992) (35)
- Neonatal Hyperglycemia Inhibits Angiogenesis and Induces Inflammation and Neuronal Degeneration in the Retina (2013) (35)
- Eosinophilic pancreatitis: report of a case. (1990) (35)
- Neuroglobin involvement in visual pathways through the optic nerve. (2013) (35)
- Hepatic portal venous gas after endoscopic biliary sphincterotomy. (1994) (34)
- Increase in Ocular Syphilis Cases at Ophthalmologic Reference Center, France, 2012–2015 (2018) (34)
- Detailed genetic characteristics of an international large cohort of patients with Stargardt disease: ProgStar study report 8 (2018) (34)
- AAV-Mediated Gene Delivery to 3D Retinal Organoids Derived from Human Induced Pluripotent Stem Cells (2020) (34)
- Human platelet suspension stimulates porcine retinal glial proliferation and migration in vitro. (2000) (34)
- Probing dynamic processes in the eye at multiple spatial and temporal scales with multimodal full field OCT. (2019) (34)
- Thioredoxin rod-derived cone viability factor protects against photooxidative retinal damage. (2015) (34)
- Foxg1-Cre Mediated Lrp2 Inactivation in the Developing Mouse Neural Retina, Ciliary and Retinal Pigment Epithelia Models Congenital High Myopia (2015) (34)
- Involvement of Pleiotrophin in CNTF-mediated differentiation of the late retinal progenitor cells. (2006) (33)
- Ophthalmic epidemiology in Europe: the “European Eye Epidemiology” (E3) consortium (2016) (33)
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- Modeling PRPF31 retinitis pigmentosa using retinal pigment epithelium and organoids combined with gene augmentation rescue (2022) (0)
- CAS CLINIQUE From pancreatic intraepithelial neoplasia to cancer : a dramatic progression with Kras status analysis (2005) (0)
- 1999 XIII International Biophysics Congress 19-24 September 1999 New Delhi Abstracts Suppl (2016) (0)
- Non-contact full-field optical coherence tomography: a novel tool for in vivo imaging of the human cornea (Conference Presentation) (2017) (0)
- [Dark times]. (2020) (0)
- Implant has three-dimensional geometry for the electrical stimulation of a nerve structure (2010) (0)
- A Regulatory Domain Is Required for Foxn4 Activity During Retinogenesis (2011) (0)
- Chronic recurrent bilateral granulomatous iridocyclitis in an 18-year-old woman (2018) (0)
- Clinical uses of time-domain FF-OCT in anterior eye (2022) (0)
- [Assessment by means of endoscopic pancreatography of the results of surgical treatment of chronic pancreatittis (author's transl)]. (1978) (0)
- Molecular Genetics of Retinoblastoma (2003) (0)
- Unusual Complication After Ranibizumab Intra Vitreous Injection: Takotsubo Syndrome (2010) (0)
- High resolution structural phenotyping of intermediate and advanced non-neovascular age-related macular degeneration (2020) (0)
- [Malacoplasia of the cystic duct (author's transl)]. (1976) (0)
- Use of diltiazem for the treatment of pathologies of the retina (1999) (0)
- 4699 Malignant intraductal papillary mucinous tumors of the pancreas: prognostic factors after surgery. (2000) (0)
- [Complications following endoscopic papillotomy--results of an international survey]. (1987) (0)
- A Low Cost and Simple Imaging Technique for Eye Structures: Eye Fundus, Ciliary Bodies, Fluorescein Angiography, and Irido-Corneal-Angle (2008) (0)
- [Retinopathy of prematurity complicated by late glaucoma: a case report]. (2008) (0)
- Correlation between visual function and an objective evaluation of the ability of glaucomatous patients to perform daily living activities (2017) (0)
- Long-term Transgene Expression And Safety Of a rAAV2 Approach Of Gene Therapy For Leber Hereditary Optic Neuropathy (2011) (0)
- Long term visual restoration using optogenetic engineering of retinal ganglion cells with AAV2.7m8- ChrimsonR-tdTomato (2017) (0)
- Multimodal imaging including semiquantitative short-wavelength and near-infrared autofluorescence in achromatopsia (2018) (0)
- BIO201: a new drug candidate for the treatment of dry AMD (2016) (0)
- Antagonists of mineralocorticoid receptors in the treatment of chronic central serous chorioretinopathy: a case series. (2014) (0)
- Mo-derived perivascular macrophage recruitment protects against endothelial cell death in retinal vein occlusion (2019) (0)
- Findings In Detection Of Herpesviridae By Real-time Polymerase Chain Reaction And Intraocular Antibody Production In A Case-series Of Anterior Uveitis (2012) (0)
- [Complications of biliary lithiasis. Etiology, diagnosis, principles of treatment]. (1991) (0)
- A transcriptome-wide association study based on 27 tissues identifies 106 genes potentially relevant for disease pathology in age-related macular degeneration (2020) (0)
- Arterio-venous Nicking and Dynamic Retinal Microvascular (2009) (0)
- Macular Dystrophies: Management and Interventions (2016) (0)
- [Partial embolization of the spleen. Apropos of a case report--review of the literature]. (1985) (0)
- Indirect Comparison of Lenadogene Nolparvovec Gene Therapy Versus Natural History in Patients with Leber Hereditary Optic Neuropathy Carrying the m.11778G>A MT-ND4 Mutation (2022) (0)
- Safety and Efficacy of Retinal Optogenetic Therapy in Canine Models (2013) (0)
- Enhanced Depth Imaging Oct For Choroidal Naevi (2011) (0)
- The retinal phenotype of an animal model of the HANAC syndrome (2013) (0)
- [Endoscopic treatment of an infected hydatic cyst complicated by a biliary fistula]. (2009) (0)
- La formation en endoscopie digestive (1991) (0)
- Intra ocular Foreign Bodies (IOFBs): Retrospective Analysis and Management About 56 Cases (2009) (0)
- Development of two gene therapy approaches for Complete Congenital Stationary Night Blindness (cCSNB) (2018) (0)
- Extensive myelinated retinal nerve fibres and bilateral foveal hypoplasia: A specific clinical entity (2022) (0)
- Intraductal papillary mucinous tumors of the pancreas (IPMTP): Particularities of malignant forms (1998) (0)
- In vivo retinal cells visible without adaptive optics using a novel full‐field OCT (2018) (0)
- Natural History of Retinal function and structure in a French cohort of patients with Usher Syndrome Type 1 due to MYO7A Mutations. (2017) (0)
- Structural and functional assessment of cone photoreceptors in patients with rhodopsin mutation. (2014) (0)
- [On the way]. (2021) (0)
- Epidemiology of Retinal Dystrophies in a French Cohort of Patients (2008) (0)
- Identifying and Overcoming Challenges in Developing Effective Treatments for Usher 1B: A Workshop Report (2023) (0)
- Visual acuity and optical flow in primate retinal ganglion cells treated with an optogenetic vision restoration strategy using ChrimsonR (2017) (0)
- Neuroprotective role of tumor necrosis factor alpha in the retina following ischemia. (2000) (0)
- [Angiographic aspects observed in pancreatic tumors (12 cases)]. (1969) (0)
- Meganuclease Targeting HSV-1 Protects Against Corneal Endothelitis ex-vivo and in-vivo (2013) (0)
- Diagnostic and therapeutic challenges. (2014) (0)
- Role of Dexamethasone preventing Müller glial cells swelling (2016) (0)
- Treats And Traps Of Homozygosity Mapping: Compound Heterozygosity In Consanguineous Retinal Dystrophy Families (2011) (0)
- Intraocular Injections of JP4-039 Protects the Retina from Radiation Retinopathy (2019) (0)
- Visual phenotyping in mutant mice deleted for the taurine-transporter gene (2014) (0)
- Iconographies supplémentaires de l'article : Lithiase lacrymale : diagnostic par l'endoscopie nasale (2008) (0)
- Department of Error (2014) (0)
- Imaging the structure and dynamic activity of retinal microglia and macrophage-like cells in the living human eye (2022) (0)
- [Retinal detachment associated with extensive sclerectasia in a patient presenting with very accentuated kyphoscoliosis]. (1983) (0)
- 4689 Dorsal duct stenting and endoscopic sphincterotomy of the minor papilla in pancreas divisum. (2000) (0)
- A Phase III b, Multicenter Study of the Efficacy and Safety of Aflibercept Switch in Patients With Exudative AMD With Retinal Pigment Epithelium Detachment, Previously Treated With Ranibizumab Intravitreal Injections. The ARI2 Study. (2016) (0)
- Identification and Localization of the Constituents of the Sarcoglycan Complex in Retinae From Wild–Type and Dystrophins Deficient Mice (mdx3cv) (2005) (0)
- Identification and Characterization of Mouse and Human Rdcvf and Rdcvf2 Promoters (2008) (0)
- Restoring vision (2018) (0)
- Adaptive Optics Flood Illumination Ophthalmoscopy in Non-Human Primates: findings in normal and short-term induced detached retinae. (2023) (0)
- [Distomatosis of the bile ducts, value of ultrasonics (apropos of a new case)]. (1987) (0)
- Restoring Vision to the Blind: Neuroprotection (2014) (0)
- Spectral-domain Optical Coherence Tomography In Acute Macular Neuroretinopathy (2012) (0)
- Reply to selected summary: Endoscopic pancreatic cystoduodenostomy (Gastroenterology 1988;94:1510–1) (1988) (0)
- High resolution imaging of intracellular dynamics in explanted retinas with dynamic full-field OCT (Conference Presentation) (2017) (0)
- [Current indications for SF6 in vitreo-retinal surgery. Preliminary report]. (1984) (0)
- [Oculomotor paralysis and Lyme disease]. (1990) (0)
- Ex vivo characterization of photovoltaic subretinal implants using non-human blind primate retinas (2016) (0)
- Rare conjunctival tumors:(choristomas, neurinomas, sebaceous carcinomas…..) (2018) (0)
- Busskamp Responses in Retinitis Pigmentosa Genetic Reactivation of Cone Photoreceptors Restores Visual (2011) (0)
- Determination of the Neuroprotective Index for Neuroprotective Treatments Based on a Mouse Model of Retinitis Pigmentosa (2005) (0)
- Ectopic expression of a mechanosensitive channel confers spatiotemporal resolution to ultrasound stimulations of neurons for visual restoration. (2023) (0)
- Neuroglobin And Physiology Of Retinal Ganglion Cells (2011) (0)
- IL-1β induces rod degeneration through the disruption of retinal glutamate homeostasis (2020) (0)
- Characterization of Genes Expressed During Early Retinal Development: Role of Foxn4 and Its Functional Domains in Retinal Differentiation (2005) (0)
- Expression and Clustered Distribution of the Potassium Channel Kir4.1 and Aquaporin 4 in the Retina of Dystrophin Protein Dp71 Null-mice (2003) (0)
- Topical instillations of Benzalkonium Chloride alter the extracellular activity of the ciliary nerve (2017) (0)
- The Antiepileptic Drug, Vigabatrin, Induces Retinal Plasticity (2007) (0)
- in vitro photoprotective effect of optical filters on retinal pigment epithelium cells exposed to moderate daylight-mimicking conditions (2018) (0)
- Percutaneous ethanol injection therapy of large hepatic tumors: a stereotaxic echo-guided approach. (1999) (0)
- Aspects IRM évocateurs d’une neuropathie optique de Leber : à propos de 26 patients (2015) (0)
- Strategies To Identify Genetic Variants In Autosomal Recessive Rod-cone Dystrophy Patients (2012) (0)
- Modification of pure pancreatic secretion in patients with chronic renal insufficiency treated by hemo dialysis (1980) (0)
- P2rx7 deficiency does not alter subretinal Mononuclear Phagocytes recruitment nor photoreceptor loss 4 days after retinal detachment. (2015) (0)
- 3-Deoxyanthocyanidins protect efficiently RPE cells and photoreceptors against A2E-mediated phototoxicity (2017) (0)
- Behavioural responses to a photovoltaic subretinal prosthesis implanted in non-human primates (2019) (0)
- βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells (2021) (0)
- Comparative Study Of The Cellular Triad - Müller Cells, Astrocytes, Vessels - Between Normal And Dystrophin 71 Deficient Mice Using An AAV Variant Targeting Müller Cells (2012) (0)
- Meganuclease Targeting Herpes Simplex Virus type I protects Against Viral Endothelitis: an organ culture model (2011) (0)
- Morphometry of retinal arterioles after initiation of hypotensive treatment: an adaptive optics imaging study. (2014) (0)
- [Complications of endoscopic catheterization of the papilla. Proposed emergency surgery]. (1976) (0)
- Optogenetic visual restoration using ChrimsonR: Photoactivation below safety radiation limit in retinal ganglion cell populations from non-human primates (2016) (0)
- Visual restoration by an infrared photovoltaic implant and by optogenetic therapy: validation in non-human primates (2019) (0)
- Contribution of "en face" SD‐OCT in inflammatory diseases (2014) (0)
- [Myopia and retinal detachment]. (1997) (0)
- CHRONIC ORAL TREATMENT WITH BIO201 PRESERVES RETINAL FUNCTION IN A DRY AMD EXPERIMENTAL MODEL (2018) (0)
- [Medical and endoscopic treatment of chronic pancreatitis]. (1996) (0)
- Whole exome sequencing identifies a new ciliary gene in autosomal recessive rod-cone dystrophy (2014) (0)
- Enhancing contrast of in-vivo human retinal ganglion cells with multi-offset adaptive optics scanning laser ophthalmoscope (2021) (0)
- Near Infrared Adaptive Optics Flood illumination ophthalmoscope Angiography (2018) (0)
- Retinal distribution of cone and retinal ganglion cell degenerations in taurine-depleted mice (2015) (0)
- 12th Meeting of the European Association for the Study of the Liver (1977) (0)
- Cover Image, Volume 113, Number 12, December 2016. (2016) (0)
- Immunocytochemical Localization of Nicotinic Receptors in the Frog Retina: Physiological Correlates (1988) (0)
- Evidence of subretinal migration of melanin-loaded cells during dry age-related macular degeneration (2015) (0)
- Pure culture of adult mammalian cone photoreceptors: electrophysiological characterization. (2004) (0)
- Gene Therapy for CSNB associated with GRM6 gene defects (2016) (0)
- Diabetic retinopathy: AGE–induced neuronal degeneration in retinal explants. (2004) (0)
- [The investigation of ocular kinetics using a diode visual stimulator (author's transl)]. (1982) (0)
- Functional Genomics Study of the RdCVF-/- Mouse Model (2008) (0)
- Indirect Comparison of Lenadogene Nolparvovec Gene Therapy Versus Natural History in Patients with Leber Hereditary Optic Neuropathy Carrying the m.11778G>A MT-ND4 Mutation (2022) (0)
- Creation of a Mouse Retinal Dp71 Vector and Expression In Vitro of a GFP-Dp71 Fusion Protein (2011) (0)
- Shedding light on myopia by studying complete congenital stationary night blindness (2022) (0)
- [Percutaneous alcoholization guided by ultrasonography for cancer of the pancreas: a new therapeutic possibility?]. (1990) (0)
- Natural History of Experimental Branch Retinal Vein Occlusion in Rodents (2005) (0)
- Adaptive optics and psychophysical measures for anatomical and functional cone patterns association in normal subjects (2013) (0)
- Age-related preference for geometric spatial cues during real-world navigation (2019) (0)
- CORRESPONDENCE Readers are encouraged to write Letters to the f:dltor. (1976) (0)
- Contents, Vol. 8, 1991 (1991) (0)
- Taurine Enhances Retinal Ganglion Cell Survival Through GabaB Receptor Activation (2012) (0)
- [Kimura's disease involving the lacrimal gland: Case report]. (2021) (0)
- Infrared autofluorescence in adaptive optics ophthalmoscopy for imaging retinal pigment epithelial cells in health and disease (2018) (0)
- Insulin inhibits inflammation-induced cone death in retinal detachment (2020) (0)
- A High Content Screening Platform for the Measurement of Trophic Factors in Rodent Models of Retinitis Pigmentosa (2009) (0)
- A novel mouse model for complete Congenital Stationary Night Blindness (cCSNB) (2014) (0)
- Visual brain plasticity induced by central and peripheral visual field loss (2018) (0)
- Analysis Of Environmental Factors In A French Population With Exudative Age-related Macular Degeneration (2011) (0)
- Intravitreal injection of rAAV2/2–ND4 (GS010): immune responses and ocular inflammation in non-human primates and patients with Leber Hereditary Optic Neuropathy (LHON) (2016) (0)
- Identification of mutations in CACNA1F in patients with incomplete CSNB applying next generation sequencing approaches (2017) (0)
- Stimulation of Insulin Signaling Reverses Inflammation-Induced Cone Death in Retinal Detachment (2020) (0)
- [Asymmetry and anomalies of accommodation]. (1987) (0)
- Investigating retinal disease with in vivo near-infrared autofluorescence adaptive optics imaging of retinal pigment epithelium (2019) (0)
- The optical Stiles-Crawford effect strongly affects photoreceptor imaging in diseased retina. (2015) (0)
- The Effect Of Aging On The Cone Function In Dogs (2006) (0)
- Lifting the iron curtain of vision (2023) (0)
- Modeling the dynamics of light-driven microbial opsin ChrimsonR (2017) (0)
- Detection and Treatment of Capillary and Venous Macroaneurysms: Interest of Indocyanine Green Angiography (2009) (0)
- [Surgical management of sub-retinal haemorrhage secondary to polypoidal choroidal vasculopathy]. (2011) (0)
- CC2D2A mutations lead to variable phenotypes in a family with retinal dystrophy (2017) (0)
- Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells (2018) (0)
- Variability of Retinal Layers and Its Relationship to Total Thickness Morphology of Retinal Layers in Healthy Subjects Using Spectral Domain Oct(sd-oct (2009) (0)
- The clinical course of Stargardt disease in a French cohort of patients. (2015) (0)
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