Josef Martin Pfeilschifter
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(Suggest an Edit or Addition)Josef Martin Pfeilschifter's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Cyclooxygenase‐independent actions of cyclooxygenase inhibitors (2001) (768)
- Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair. (2000) (541)
- Physiology and pathophysiology of sphingolipid metabolism and signaling. (2000) (440)
- Biglycan, a Danger Signal That Activates the NLRP3 Inflammasome via Toll-like and P2X Receptors* (2009) (420)
- A transgenic mouse model of inducible macrophage depletion: effects of diphtheria toxin-driven lysozyme M-specific cell lineage ablation on wound inflammatory, angiogenic, and contractive processes. (2009) (344)
- Leptin enhances wound re-epithelialization and constitutes a direct function of leptin in skin repair. (2000) (312)
- IL-1 family nomenclature (2010) (302)
- Signaling by the Matrix Proteoglycan Decorin Controls Inflammation and Cancer Through PDCD4 and MicroRNA-21 (2011) (284)
- Nitric oxide triggers enhanced induction of vascular endothelial growth factor expression in cultured keratinocytes (HaCaT) and during cutaneous wound repair (1999) (239)
- The function of nitric oxide in wound repair: inhibition of inducible nitric oxide-synthase severely impairs wound reepithelialization. (1999) (228)
- Anti-inflammatory properties of pro-inflammatory interferon-gamma. (2003) (220)
- Amplification of IL-1β-Induced Matrix Metalloproteinase-9 Expression by Superoxide in Rat Glomerular Mesangial Cells Is Mediated by Increased Activities of NF-κB and Activating Protein-1 and Involves Activation of the Mitogen-Activated Protein Kinase Pathways1 (2000) (217)
- Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR. (2008) (216)
- Atrial natriuretic peptide inhibits renin release from juxtaglomerular cells by a cGMP-mediated process. (1986) (211)
- Cytokine-stimulated secretion of group II phospholipase A2 by rat mesangial cells. Its contribution to arachidonic acid release and prostaglandin synthesis by cultured rat glomerular cells. (1993) (205)
- Inducible NO synthase: role in cellular signalling. (1999) (193)
- Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2. (2007) (193)
- Nitric oxide drives skin repair: novel functions of an established mediator. (2002) (190)
- Sphingosine 1-Phosphate Cross-activates the Smad Signaling Cascade and Mimics Transforming Growth Factor-β-induced Cell Responses* (2004) (188)
- Ceramide-binding and activation defines protein kinase c-Raf as a ceramide-activated protein kinase. (1996) (186)
- Interleukin 1 and tumor necrosis factor synergistically stimulate prostaglandin synthesis and phospholipase A2 release from rat renal mesangial cells. (1989) (185)
- Translational Control of Inducible Nitric Oxide Synthase by IL-13 and Arginine Availability in Inflammatory Macrophages 1 (2003) (184)
- Posttranslational Modification of the AU-Rich Element Binding Protein HuR by Protein Kinase Cδ Elicits Angiotensin II-Induced Stabilization and Nuclear Export of Cyclooxygenase 2 mRNA (2008) (184)
- Nitric Oxide Increases the Decay of Matrix Metalloproteinase 9 mRNA by Inhibiting the Expression of mRNA-Stabilizing Factor HuR (2003) (176)
- Breaking tolerance to the natural human liver autoantigen cytochrome P450 2D6 by virus infection (2008) (174)
- Arginase 1 overexpression in psoriasis: limitation of inducible nitric oxide synthase activity as a molecular mechanism for keratinocyte hyperproliferation. (2002) (171)
- Modulation of mRNA stability as a novel therapeutic approach. (2007) (170)
- The proteoglycan biglycan regulates expression of the B cell chemoattractant CXCL13 and aggravates murine lupus nephritis. (2010) (169)
- Human Urotensin II Is a Novel Activator of NADPH Oxidase in Human Pulmonary Artery Smooth Muscle Cells (2005) (165)
- Expressional Regulation of Angiopoietin-1 and -2 and the Tie-1 and -2 Receptor Tyrosine Kinases during Cutaneous Wound Healing: A Comparative Study of Normal and Impaired Repair (2001) (158)
- Two distinct signaling pathways trigger the expression of inducible nitric oxide synthase in rat renal mesangial cells. (1994) (157)
- Severely impaired insulin signaling in chronic wounds of diabetic ob/ob mice: a potential role of tumor necrosis factor-alpha. (2006) (157)
- Transforming growth factor β2 inhibits interleukin 1β- and tumour necrosis factor α-induction of nitric oxide synthase in rat renal mesangial cells (1991) (153)
- Molecular mechanisms of dexamethasone inhibition of nitric oxide synthase expression in interleukin 1 beta-stimulated mesangial cells: evidence for the involvement of transcriptional and posttranscriptional regulation. (1996) (152)
- Nitric oxide modulates expression of matrix metalloproteinase-9 in rat mesangial cells. (2000) (150)
- Expression and Release of IL-18 Binding Protein in Response to IFN-γ1 (2001) (149)
- SphK1 Regulates Proinflammatory Responses Associated with Endotoxin and Polymicrobial Sepsis (2010) (146)
- Tumor necrosis factor-alpha and lipopolysaccharide induce apoptotic cell death in bovine glomerular endothelial cells. (1999) (146)
- Molecular mechanisms of inducible nitric oxide synthase gene expression by IL-1beta and cAMP in rat mesangial cells. (1998) (145)
- Dual Effect of Ceramide on Human Endothelial Cells: Induction of Oxidative Stress and Transcriptional Upregulation of Endothelial Nitric Oxide Synthase (2002) (142)
- Regulation of gene expression by nitric oxide (2001) (141)
- Systemic anti-TNFalpha treatment restores diabetes-impaired skin repair in ob/ob mice by inactivation of macrophages. (2007) (141)
- Interleukin 1 and tumor necrosis factor stimulate cGMP formation in rat renal mesangial cells (1990) (140)
- Nitric Oxide Donors Induce Stress Signaling via Ceramide Formation in Rat Renal Mesangial Cells* (1999) (136)
- Molecular cloning of the rat inducible nitric oxide synthase gene promoter. (1996) (134)
- The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia. (2009) (132)
- Ceramide binds to the CaLB domain of cytosolic phospholipase A2 and facilitates its membrane docking and arachidonic acid release (2001) (130)
- Mechanisms of suppression of inducible nitric-oxide synthase (iNOS) expression in interferon (IFN)-gamma-stimulated RAW 264.7 cells by dexamethasone. Evidence for glucocorticoid-induced degradation of iNOS protein by calpain as a key step in post-transcriptional regulation. (1997) (127)
- Nitric oxide and superoxide induced p53 and Bax accumulation during mesangial cell apoptosis. (1997) (122)
- Platelet-derived growth factor and angiotensin II stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: comparison of hypertrophic and hyperplastic agonists. (1995) (121)
- Selective ceramide binding to protein kinase C-alpha and -delta isoenzymes in renal mesangial cells. (1998) (120)
- Wound Healing in Mice with High-Fat Diet- or ob Gene-Induced Diabetes-Obesity Syndromes: A Comparative Study (2011) (118)
- Interleukin 1β and tumour necrosis factor α induce a macrophage‐type of nitric oxide synthase in rat renal mesangial cells (1992) (116)
- Glucocorticoid-mediated suppression of cytokine-induced matrix metalloproteinase-9 expression in rat mesangial cells: involvement of nuclear factor-kappaB and Ets transcription factors. (2002) (115)
- Induction of inducible nitric oxide synthase and its corresponding tetrahydrobiopterin-cofactor-synthesizing enzyme GTP-cyclohydrolase I during cutaneous wound repair. (1998) (112)
- CXCL10 promotes liver fibrosis by prevention of NK cell mediated hepatic stellate cell inactivation. (2010) (111)
- The Interleukin-22/STAT3 Pathway Potentiates Expression of Inducible Nitric-oxide Synthase in Human Colon Carcinoma Cells* (2007) (111)
- The balance between nitric oxide and superoxide determines apoptotic and necrotic death of rat mesangial cells. (1997) (110)
- Stimulation by extracellular ATP and UTP of the mitogen‐activated protein kinase cascade and proliferation of rat renal mesangial cells (1994) (110)
- Leptin and wound inflammation in diabetic ob/ob mice: differential regulation of neutrophil and macrophage influx and a potential role for the scab as a sink for inflammatory cells and mediators. (2003) (109)
- Biglycan-triggered TLR-2- and TLR-4-signaling exacerbates the pathophysiology of ischemic acute kidney injury. (2014) (109)
- Pertussis toxin abolishes angiotensin II-induced phosphoinositide hydrolysis and prostaglandin synthesis in rat renal mesangial cells. (1986) (108)
- New players on the center stage: sphingosine 1-phosphate and its receptors as drug targets. (2008) (107)
- Reduced nitric oxide in sinus epithelium of patients with radiologic maxillary sinusitis and sepsis. (2003) (106)
- Nitric oxide donors induce apoptosis in glomerular mesangial cells, epithelial cells and endothelial cells. (1996) (103)
- Cross‐talk between transmembrane signalling systems: a prerequisite for the delicate regulation of glomerular haemodynamics by mesangial cells (1989) (99)
- The epidermal growth factor stimulates sphingosine kinase-1 expression and activity in the human mammary carcinoma cell line MCF7. (2005) (99)
- Tumoural CXCL16 expression is a novel prognostic marker of longer survival times in renal cell cancer patients. (2009) (98)
- Interleukin-1β, tumor necrosis factor and forskolin stimulate the synthesis and secretion of group II phospholipase A2 in rat mesangial cells (1991) (97)
- Interferon-gamma mediates gene expression of IL-18 binding protein in nonleukocytic cells. (2000) (96)
- A novel keratinocyte mitogen: regulation of leptin and its functional receptor in skin repair. (2001) (96)
- Cross-talk between secretory phospholipase A2 and cytosolic phospholipase A2 in rat renal mesangial cells. (1997) (95)
- Selective inhibition of cyclooxygenase 2. (1994) (94)
- Potentiation of Tumor Necrosis Factor α-induced Secreted Phospholipase A2 (sPLA2)-IIA Expression in Mesangial Cells by an Autocrine Loop Involving sPLA2 and Peroxisome Proliferator-activated Receptor α Activation* (2003) (93)
- Prediction of Acute Renal Allograft Rejection by Urinary Monokine Induced by IFN-γ (MIG) (2005) (93)
- Comparison of extracellular ATP and UTP signalling in rat renal mesangial cells. No indications for the involvement of separate purino- and pyrimidino-ceptors. (1990) (89)
- ADAM10 is upregulated in melanoma metastasis compared with primary melanoma. (2010) (89)
- Activation of protein kinase C subtypes alpha, gamma, delta, epsilon, zeta, and eta by tumor-promoting and nontumor-promoting agents. (1997) (88)
- Protective properties of inhaled IL-22 in a model of ventilator-induced lung injury. (2011) (88)
- Hypoxia induces macrophage inflammatory protein‐2 (MIP‐2) gene expression in murine macrophages via NF‐κB: the prominent role of p42/ p44 and PI3 kinase pathways (2004) (87)
- MicroRNA-145 targets the metalloprotease ADAM17 and is suppressed in renal cell carcinoma patients. (2013) (87)
- Tandem Phosphorylation of Serines 221 and 318 by Protein Kinase Cδ Coordinates mRNA Binding and Nucleocytoplasmic Shuttling of HuR (2010) (87)
- Nitric oxide: an inflammatory mediator of glomerular mesangial cells. (1993) (87)
- Cyclosporin A augments angiotensin II-stimulated rise in intracellular free calcium in vascular smooth muscle cells. (1987) (85)
- Cyclooxygenase-1-coupled prostaglandin biosynthesis constitutes an essential prerequisite for skin repair. (2003) (83)
- Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin. (2007) (83)
- Molecular Mechanisms of TGFβ Receptor-Triggered Signaling Cascades Rapidly Induced by the Calcineurin Inhibitors Cyclosporin A and FK5061 (2008) (82)
- Identification of copper/zinc superoxide dismutase as a nitric oxide-regulated gene in human (HaCaT) keratinocytes: implications for keratinocyte proliferation. (2000) (82)
- Sphingosine kinase-1 is a hypoxia-regulated gene that stimulates migration of human endothelial cells. (2008) (81)
- The cyclopentenone prostaglandin 15-deoxy-Delta(12,14)-prostaglandin J2 ameliorates ischemic acute renal failure. (2004) (81)
- Possible regulatory functions of protein kinase C-alpha and -epsilon isoenzymes in rat renal mesangial cells. Stimulation of prostaglandin synthesis and feedback inhibition of angiotensin II-stimulated phosphoinositide hydrolysis. (1991) (80)
- ATP Potentiates Interleukin-1β-induced MMP-9 Expression in Mesangial Cells via Recruitment of the ELAV Protein HuR* (2003) (79)
- New insights into the mechanism for clearance of apoptotic cells. (2000) (79)
- Counterregulation of interleukin-18 mRNA and protein expression during cutaneous wound repair in mice. (1999) (79)
- Decline in the expression of copper/zinc superoxide dismutase in the kidney of rats with endotoxic shock: Effects of the superoxide anion radical scavenger, tempol, on organ injury (1998) (78)
- The Dipeptidyl Peptidase-4 Inhibitor Linagliptin Attenuates Inflammation and Accelerates Epithelialization in Wounds of Diabetic ob/ob Mice (2012) (78)
- Activation of sphingosine kinase 2 is an endogenous protective mechanism in cerebral ischemia. (2011) (77)
- Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1 beta-stimulated rat mesangial cells. (1995) (77)
- CXCL16 is expressed in podocytes and acts as a scavenger receptor for oxidized low-density lipoprotein. (2009) (76)
- Activation of phospholipase C and prostaglandin synthesis by [arginine]vasopressin in cultures. (1984) (75)
- Cystathionine &ggr; Lyase Sulfhydrates the RNA Binding Protein Human Antigen R to Preserve Endothelial Cell Function and Delay Atherogenesis (2019) (75)
- Imbalance in distribution of functional autologous regulatory T cells in rheumatoid arthritis (2007) (75)
- Pyrrolidine dithiocarbamate differentially affects interleukin 1 beta- and cAMP-induced nitric oxide synthase expression in rat renal mesangial cells. (1994) (75)
- Expression and activity of arginase isoenzymes during normal and diabetes-impaired skin repair. (2003) (75)
- Interleukin-18 bioactivity: a novel target for immunopharmacological anti-inflammatory intervention. (2004) (75)
- Differential regulation of vascular endothelial growth factor and its receptor fms-like-tyrosine kinase is mediated by nitric oxide in rat renal mesangial cells. (1999) (74)
- Large induction of the chemotactic cytokine RANTES during cutaneous wound repair: a regulatory role for nitric oxide in keratinocyte-derived RANTES expression. (2000) (74)
- Coexpression of tyrosine hydroxylase, GTP cyclohydrolase I, aromatic amino acid decarboxylase, and vesicular monoamine transporter 2 from a helper virus-free herpes simplex virus type 1 vector supports high-level, long-term biochemical and behavioral correction of a rat model of Parkinson's disease. (2004) (72)
- Decorin deficiency in diabetic mice: aggravation of nephropathy due to overexpression of profibrotic factors, enhanced apoptosis and mononuclear cell infiltration. (2009) (72)
- Glucocorticoids inhibit lipopolysaccharide‐induced up‐regulation of arginase in rat alveolar macrophages (2001) (71)
- Role of protein kinase C in inhibition of renin release caused by vasoconstrictors. (1986) (71)
- Downregulation of iNOS expression in rat mesangial cells by special extracts of Harpagophytum procumbens derives from harpagoside-dependent and independent effects. (2004) (71)
- Sphingosine-1-phosphate: a Janus-faced mediator of fibrotic diseases. (2013) (71)
- Biglycan, a Nitric Oxide-regulated Gene, Affects Adhesion, Growth, and Survival of Mesangial Cells* (2003) (70)
- Expression of nitric oxide synthase in rat glomerular mesangial cells mediated by cyclic AMP (1994) (70)
- The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells (2006) (70)
- Prolactin upregulates sphingosine kinase-1 expression and activity in the human breast cancer cell line MCF7 and triggers enhanced proliferation and migration. (2007) (70)
- Mesangial Cells Orchestrate Inflammation in the Renal Glomerulus (1994) (69)
- Inhibition of Cytokine-induced Matrix Metalloproteinase 9 Expression by Peroxisome Proliferator-activated Receptor α Agonists Is Indirect and Due to a NO-mediated Reduction of mRNA Stability* (2002) (69)
- Transforming growth factor-beta2 upregulates sphingosine kinase-1 activity, which in turn attenuates the fibrotic response to TGF-beta2 by impeding CTGF expression. (2009) (69)
- Biglycan evokes autophagy in macrophages via a novel CD44/Toll-like receptor 4 signaling axis in ischemia/reperfusion injury. (2019) (68)
- Anti‐inflammatory effects of sevoflurane and mild hypothermia in endotoxemic rats (2007) (68)
- Molecular mimicry rather than identity breaks T-cell tolerance in the CYP2D6 mouse model for human autoimmune hepatitis. (2013) (67)
- Application of interleukin-22 mediates protection in experimental acetaminophen-induced acute liver injury. (2013) (67)
- Lipids as targets for novel anti-inflammatory therapies. (2009) (67)
- Interleukin-1 beta- and forskolin-induced synthesis and secretion of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by transforming growth factor-beta 2. (1992) (67)
- Akt1 controls insulin-driven VEGF biosynthesis from keratinocytes: implications for normal and diabetes-impaired skin repair in mice. (2009) (67)
- Interleukin‐1β and transforming growth factor‐β2 enhance cytosolic high‐molecular‐mass phospholipase A2 activity and induce prostaglandin E2 formation in rat mesangial cells (1992) (66)
- Rapid and delayed p42/p44 mitogen-activated protein kinase activation by nitric oxide: the role of cyclic GMP and tyrosine phosphatase inhibition. (1998) (66)
- Nitric oxide down‐regulates the expression of the catalytic NADPH oxidase subunit Nox1 in rat renal mesangial cells (2006) (65)
- Wound inflammation in diabetic ob/ob mice: functional coupling of prostaglandin biosynthesis to cyclooxygenase-1 activity in diabetes-impaired wound healing. (2005) (65)
- Interleukin-1β Induces Chronic Activation and de Novo Synthesis of Neutral Ceramidase in Renal Mesangial Cells* (2001) (65)
- Quantitative Persulfide Site Identification (qPerS-SID) Reveals Protein Targets of H2S Releasing Donors in Mammalian Cells (2016) (64)
- Dexamethasone differentially affects interleukin 1 beta- and cyclic AMP-induced nitric oxide synthase mRNA expression in renal mesangial cells. (1994) (64)
- Inducible NO synthase and antibacterial host defence in times of Th17/Th22/T22 immunity (2011) (64)
- A Novel Mode of Action of the Putative Sphingosine Kinase Inhibitor 2-(p-hydroxyanilino)-4-(p-chlorophenyl) Thiazole (SKI II): Induction of Lysosomal Sphingosine Kinase 1 Degradation (2010) (64)
- IL-18 is expressed in the intercalated cell of human kidney. (2007) (63)
- Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y2 purinoceptor in renal mesangial cells (2002) (63)
- Regulation of eNOS in normal and diabetes-impaired skin repair: implications for tissue regeneration. (2002) (63)
- CD14 works with toll-like receptor 2 to contribute to recognition and control of Listeria monocytogenes infection. (2008) (63)
- Effect of extracellular ATP on contraction, cytosolic calcium activity, membrane voltage and ion currents of rat mesangial cells in primary culture (1993) (62)
- Role of phospholipase C and protein kinase C in vasoconstrictor-induced prostaglandin synthesis in cultured rat renal mesangial cells. (1986) (62)
- Nitric Oxide Induces Degradation of the Neutral Ceramidase in Rat Renal Mesangial Cells and Is Counterregulated by Protein Kinase C* (2002) (62)
- Effect of cyclic AMP and prostaglandin E2 on the induction of nitric oxide- and prostanoid-forming pathways in cultured rat mesangial cells. (1996) (62)
- Dimethylfumarate reduces leukocyte rolling in vivo through modulation of adhesion molecule expression. (2008) (61)
- Lipoteichoic acid induces delayed protection in the rat heart: A comparison with endotoxin. (2000) (61)
- Nitric oxide induces MIP‐2 transcription in rat renal mesangial cells and in a rat model of glomerulonephritis (2001) (61)
- Down-regulation of protein kinase C potentiates angiotensin II-stimulated polyphosphoinositide hydrolysis in vascular smooth-muscle cells. (1989) (61)
- Thrombolysis with recombinant tissue plasminogen activator under dabigatran anticoagulation in experimental stroke (2012) (60)
- Role of prostaglandins in hypoxia-stimulated erythropoietin production. (1985) (60)
- THERAPEUTIC STRATEGIES FOR THE INHIBITION OF INDUCIBLE NITRIC OXIDE SYNTHASE—POTENTIAL FOR A NOVEL CLASS OF ANTI‐INFLAMMATORY AGENTS (1996) (60)
- IL‐22 in tissue‐protective therapy (2013) (60)
- Cytokine- and forskolin-induced synthesis of group II phospholipase A2 and prostaglandin E2 in rat mesangial cells is prevented by dexamethasone. (1991) (59)
- Glucocorticoids potently block tumour necrosis factor‐α‐ and lipopolysaccharide‐induced apoptotic cell death in bovine glomerular endothelial cells upstream of caspase 3 activation (1999) (59)
- Regulation and immunhistochemical localization of nitric oxide synthases and soluble guanylyl cyclase in mouse spinal cord following nociceptive stimulation (2000) (59)
- Nitric oxide stimulates stress‐activated protein kinases in glomerular endothelial and mesangial cells (1996) (59)
- Dexamethasone inhibits TNF‐α‐induced apoptosis and IAP protein downregulation in MCF‐7 cells (2001) (59)
- Immunocharacterization of δ‐ and ζ‐isoenzymes of protein kinase C in rat renal mesangial cells (1992) (58)
- IL-18 initiates release of matrix metalloproteinase-9 from peripheral blood mononuclear cells without affecting tissue inhibitor of matrix metalloproteinases-1: suppression by TNFα blockage and modulation by IL-10 (2002) (57)
- Prediction of acute renal allograft rejection by urinary monokine induced by IFN-gamma (MIG). (2005) (57)
- Nitric oxide and mechanisms of redox signalling: matrix and matrix-metabolizing enzymes as prime nitric oxide targets. (2001) (56)
- Sphingosine kinase 1 and 2 regulate the capacity of mesangial cells to resist apoptotic stimuli in an opposing manner (2008) (56)
- Involvement of the ABC-transporter ABCC1 and the sphingosine 1-phosphate receptor subtype S1P3 in the cytoprotection of human fibroblasts by the glucocorticoid dexamethasone (2009) (56)
- CXCL16 and oxLDL are induced in the onset of diabetic nephropathy (2009) (56)
- The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma. (2011) (55)
- The ceramide kinase inhibitor NVP‐231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death (2014) (55)
- Angiotensin II induces renal plasminogen activator inhibitor-1 and cyclooxygenase-2 expression post-transcriptionally via activation of the mRNA-stabilizing factor human-antigen R. (2009) (55)
- Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-alpha-dependent mechanism. (2006) (55)
- Altering the sphingosine-1-phosphate/ceramide balance: a promising approach for tumor therapy. (2006) (55)
- Sphingosine 1-Phosphate Produced by Sphingosine Kinase 2 Intrinsically Controls Platelet Aggregation In Vitro and In Vivo. (2015) (55)
- Extracellular ATP and UTP activation of phospholipase D is mediated by protein kinase C‐ε in rat renal mesangial cells (1993) (54)
- Characterization of CXCL16 and ADAM10 in the normal and transplanted kidney. (2008) (54)
- Immunocharacterization of protein kinase C isoenzymes in rat kidney glomeruli, and cultured glomerular epithelial and mesangial cells. (1993) (54)
- Systemically and topically supplemented leptin fails to reconstitute a normal angiogenic response during skin repair in diabetic ob/ob mice (2001) (53)
- IL-36γ/IL-1F9, an Innate T-bet Target in Myeloid Cells* (2012) (53)
- Apoptotic Cell-Derived Sphingosine-1-Phosphate Promotes HuR-Dependent Cyclooxygenase-2 mRNA Stabilization and Protein Expression1 (2008) (53)
- Serum acid sphingomyelinase is upregulated in chronic hepatitis C infection and non alcoholic fatty liver disease. (2014) (53)
- Identification of copper/zinc superoxide dismutase as a novel nitric oxide‐regulated gene in rat glomerular mesangial cells and kidneys of endotoxemic rats (1999) (53)
- Platelet-derived growth factor and fibroblast growth factor differentially regulate interleukin 1beta- and cAMP-induced nitric oxide synthase expression in rat renal mesangial cells. (1997) (53)
- Extracellular nucleotides activate the p38‐stress‐activated protein kinase cascade in glomerular mesangial cells (2000) (53)
- Cyclic AMP mimics, but does not mediate, interleukin-1- and tumour-necrosis-factor-stimulated phospholipase A2 secretion from rat renal mesangial cells. (1991) (52)
- Serum sphingolipidomic analyses reveal an upregulation of C16- ceramide and sphingosine-1-phosphate in hepatocellular carcinoma (2016) (52)
- Parathyroid hormone inhibition of Na+/phosphate cotransport in OK cells: generation of second messengers in the regulatory cascade. (1989) (52)
- Interleukin 1 beta-induced expression of nitric oxide synthase in rat renal mesangial cells is suppressed by cyclosporin A. (1995) (52)
- High-constitutive HuR phosphorylation at Ser 318 by PKC{delta} propagates tumor relevant functions in colon carcinoma cells. (2011) (52)
- Potentiation of nitric oxide synthase expression by superoxide in interleukin 1β‐stimulated rat mesangial cells (1998) (52)
- Cross-talk between nitric oxide and superoxide determines ceramide formation and apoptosis in glomerular cells. (2002) (52)
- Nitric Oxide Induces TIMP-1 Expression by Activating the Transforming Growth Factor β-Smad Signaling Pathway* (2005) (51)
- In-vivo interaction of nitric oxide and endothelin (2004) (51)
- Oncostatin M expression is functionally connected to neutrophils in the early inflammatory phase of skin repair: implications for normal and diabetes-impaired wounds. (2006) (51)
- Role of secreted modular calcium-binding protein 1 (SMOC1) in transforming growth factor β signalling and angiogenesis. (2015) (51)
- Extracellular ATP stimulates polyphosphoinositide hydrolysis and prostaglandin synthesis in rat renal mesangial cells. Involvement of a pertussis toxin-sensitive guanine nucleotide binding protein and feedback inhibition by protein kinase C. (1990) (51)
- Cyclosporin derivatives inhibit interleukin 1 beta induction of nitric oxide synthase in renal mesangial cells. (1993) (50)
- Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study (2012) (50)
- Junctional adhesion molecule (JAM)‐B supports lymphocyte rolling and adhesion through interaction with α4β1 integrin (2009) (50)
- Regulation of the mRNA-binding protein HuR by posttranslational modification: spotlight on phosphorylation. (2012) (50)
- Keratinocyte-derived chemotactic cytokines: expressional modulation by nitric oxide in vitro and during cutaneous wound repair in vivo. (2000) (50)
- Epitope spreading of the anti-CYP2D6 antibody response in patients with autoimmune hepatitis and in the CYP2D6 mouse model. (2011) (49)
- Nitric oxide stimulates the stress-activated protein kinase p38 in rat renal mesangial cells. (1999) (49)
- FTY720 Treatment in the Convalescence Period Improves Functional Recovery and Reduces Reactive Astrogliosis in Photothrombotic Stroke (2013) (49)
- Downregulation of junctional adhesion molecule-A is involved in the progression of clear cell renal cell carcinoma. (2009) (48)
- Targeting caspase-1 by inhalation-therapy: effects of Ac-YVAD-CHO on IL-1β, IL-18 and downstream proinflammatory parameters as detected in rat endotoxaemia (2007) (48)
- Sphingosine-1-Phosphate Receptor-2 Antagonists: Therapeutic Potential and Potential Risks (2016) (48)
- Apoptosis and expression of inducible nitric oxide synthase are mutually exclusive in renal mesangial cells. (1997) (48)
- Stimulation by extracellular ATP and UTP of the stress‐activated protein kinase cascade in rat renal mesangial cells (1997) (47)
- Role of cGMP as second messenger of adenosine in the inhibition of renin release. (1988) (47)
- Transforming growth factor β2 stimulates acute and chronic activation of the mitogen‐activated protein kinase cascade in rat renal mesangial cells (1994) (47)
- L1-CAM expression in ccRCC correlates with shorter patients survival times and confers chemoresistance in renal cell carcinoma cells. (2011) (46)
- Rapamycin induces the TGFbeta1/Smad signaling cascade in renal mesangial cells upstream of mTOR. (2009) (45)
- A brief exposure to isoflurane (50 s) significantly impacts on plasma cytokine levels in endotoxemic rats. (2005) (45)
- Suppression of apoptosis by glucocorticoids in glomerular endothelial cells: effects on proapoptotic pathways (2000) (45)
- Determination of leptin signaling pathways in human and murine keratinocytes. (2003) (45)
- Is renin secretion governed by the calcium permeability of the juxtaglomerular cell membrane? (1984) (44)
- IL-27 Regulates IL-18 Binding Protein in Skin Resident Cells (2012) (44)
- The role of CXCL16 and its processing metalloproteinases ADAM10 and ADAM17 in the proliferation and migration of human mesangial cells. (2008) (44)
- PPARalpha activation upregulates nephrin expression in human embryonic kidney epithelial cells and podocytes by a dual mechanism. (2005) (44)
- p68 DEAD Box RNA Helicase Expression in Keratinocytes (2004) (44)
- Early Production of IL-22 but Not IL-17 by Peripheral Blood Mononuclear Cells Exposed to live Borrelia burgdorferi: The Role of Monocytes and Interleukin-1 (2010) (43)
- Angiotensin II B-type receptor mediates phosphoinositide hydrolysis in mesangial cells. (1990) (43)
- The suppressor of cytokine signaling-3 is upregulated in impaired skin repair: implications for keratinocyte proliferation. (2006) (43)
- Loss of sphingosine kinase‐1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin‐induced DNA damage (2011) (43)
- Dexamethasone inhibits TNF-alpha-induced apoptosis and IAP protein downregulation in MCF-7 cells. (2001) (43)
- Interleukin‐1β‐induced cytosolic phospholipase A2 activity and protein synthesis is blocked by dexamethasone in rat mesangial cells (1993) (43)
- Interleukin‐18 secretion and Th1‐like cytokine responses in human peripheral blood mononuclear cells under the influence of the toll‐like receptor‐5 ligand flagellin (2006) (43)
- Interleukin‐1 stimulates de novo synthesis of mitogen‐activated protein kinase in glomerular mesangial cells (1994) (41)
- Distinct signaling pathways mediate phorbol-ester-induced and cytokine-induced inhibition of erythropoietin gene expression. (1994) (41)
- Nitrosative and oxidative stress induced heme oxygenase-1 accumulation in rat mesangial cells. (1998) (41)
- Regulation of interleukin-18 (IL-18) expression in keratinocytes (HaCaT): implications for early wound healing. (2000) (41)
- Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cells (1999) (41)
- Tetrahydrobiopterin is a limiting factor of nitric oxide generation in interleukin 1 beta-stimulated rat glomerular mesangial cells. (1994) (41)
- Tumour promotor 12‐O‐tetradecanoylphorbol 13‐acetate inhibits angiotensin II‐induced inositol phosphate production and cytosolic Ca2+ rise in rat renal mesangial cells (1986) (41)
- Macrophage-Derived Heme-Oxygenase-1: Expression, Regulation, and Possible Functions in Skin Repair (2001) (41)
- INTERLEUKIN-22 DETECTED IN PATIENTS WITH ABDOMINAL SEPSIS (2010) (41)
- Platelet‐derived growth factor‐BB induces cystathionine γ‐lyase expression in rat mesangial cells via a redox‐dependent mechanism (2012) (40)
- Characterization of group X phospholipase A(2) as the major enzyme secreted by human keratinocytes and its regulation by the phorbol ester TPA. (2001) (40)
- Transforming growth factors type‐β and dexamethasone attenuate group II phospholipase A2 gene expression by interleukin‐1 and forskolin in rat mesangial cells (1992) (40)
- Hypoxia and cobalt stimulate lactate dehydrogenase (LDH) activity in vascular smooth muscle cells (1994) (39)
- Nitric oxide stimulates chronic ceramide formation in glomerular endothelial cells. (1999) (39)
- Interleukin-1 beta and tumor necrosis factor-alpha synergistically stimulate nerve growth factor synthesis in rat mesangial cells. (1991) (39)
- Extracellular nucleotides induce migration of renal mesangial cells by upregulating sphingosine kinase‐1 expression and activity (2007) (39)
- Cytokine-induced expression of tPA is differentially modulated by NO and ROS in rat mesangial cells. (2002) (39)
- Parathyroid hormone inhibition of Na+/phosphate cotransport in OK cells: requirement of protein kinase C-dependent pathway. (1989) (39)
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- Cyclosporin A and tacrolimus induce renal Erk1/2 pathway via ROS-induced and metalloproteinase-dependent EGF-receptor signaling. (2012) (38)
- Sphingolipid signaling in renal fibrosis. (2018) (38)
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- Interferon‐γ induces expression of interleukin‐18 binding protein in fibroblast‐like synoviocytes (2003) (38)
- Expression of interleukin-8, heme oxygenase-1 and vascular endothelial growth factor in DLD-1 colon carcinoma cells exposed to pyrrolidine dithiocarbamate. (2002) (37)
- Transforming growth factor beta 2 differentially modulates interleukin-1 beta- and tumour-necrosis-factor-alpha-stimulated phospholipase A2 and prostaglandin E2 synthesis in rat renal mesangial cells. (1990) (37)
- Basic fibroblast growth factor selectively enhances TNF-alpha-induced apoptotic cell death in glomerular endothelial cells: effects on apoptotic signaling pathways. (2000) (37)
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- Treatment with the immunomodulator FTY720 does not promote spontaneous bacterial infections after experimental stroke in mice (2011) (37)
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- IFNα converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets. (2013) (36)
- Variations in serum sphingolipid levels associate with liver fibrosis progression and poor treatment outcome in hepatitis C virus but not hepatitis B virus infection (2015) (36)
- Cyclosporin A inhibits PGE2 release from vascular smooth muscle cells. (1987) (36)
- Endothelial nitric oxide synthase: a determinant of TNFalpha production by human monocytes/macrophages. (2003) (36)
- Platelet-derived growth factor inhibits cytokine induction of nitric oxide synthase in rat renal mesangial cells. (1991) (36)
- Proteolytic cleavage of inducible nitric oxide synthase (iNOS) by calpain I. (2001) (35)
- Inflammatory cytokines upregulate nephrin expression in human embryonic kidney epithelial cells and podocytes. (2003) (35)
- PDGF suppresses the activation of group II phospholipase A2 gene expression by interleukin I and forskolin in mesangial cells (1991) (35)
- No Influence of Dabigatran Anticoagulation on Hemorrhagic Transformation in an Experimental Model of Ischemic Stroke (2012) (35)
- Protein kinase C from rat renal mesangial cells: its role in homologous desensitization of angiotensin II-induced polyphosphoinositide hydrolysis. (1988) (35)
- Apoptosis is triggered by the cyclic AMP signalling pathway in renal mesangial cells (1996) (35)
- Evidence for a link between histone deacetylation and Ca²+ homoeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts. (2012) (35)
- Differentiation-dependent regulation of secreted phospholipases A2 in murine epidermis. (2003) (35)
- Changing gears in the course of glomerulonephritis by shifting superoxide to nitric oxide-dominated chemistry. (2002) (34)
- Differential modulation of the cytokine-induced MMP-9/TIMP-1 protease-antiprotease system by the mTOR inhibitor rapamycin. (2011) (34)
- Elevation of serum sphingosine-1-phosphate attenuates impaired cardiac function in experimental sepsis (2016) (34)
- CYP2R1-, CYP27B1- and CYP24-mRNA expression in German type 1 diabetes patients (2007) (34)
- Interleukin-18 directly activates T-bet expression and function via p38 mitogen-activated protein kinase and nuclear factor-κB in acute myeloid leukemia–derived predendritic KG-1 cells (2007) (34)
- Molecular mechanisms of nitric oxide‐dependent inhibition of TPA‐induced matrix metalloproteinase‐9 (MMP‐9) in MCF‐7 cells (2009) (34)
- Nitric oxide augments release of chemokines from monocytic U937 cells: modulation by anti-inflammatory pathways. (2000) (33)
- Nitric oxide triggers the expression of proinflammatory and protective gene products in mesangial cells and the inflamed glomerulus. (2002) (33)
- Serum Sphingolipid Variations Associate with Hepatic Decompensation and Survival in Patients with Cirrhosis (2015) (33)
- The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen. (2011) (33)
- Protein kinase C phosphorylates and activates GTP cyclohydrolase I in rat renal mesangial cells. (1998) (33)
- Cellular mechanisms of ATP‐induced hyperpolarization in renal epitheloid MDCK‐cells (1991) (33)
- Potentiation of angiotensin II‐stimulated phosphoinositide hydrolysis, calcium mobilization and contraction of renal mesangial cells upon down‐regulation of protein kinase C (1990) (33)
- TLR-ligand stimulated interleukin-23 subunit expression and assembly is regulated differentially in murine plasmacytoid and myeloid dendritic cells. (2007) (33)
- Does nitric oxide, an inflammatory mediator of glomerular mesangial cells, have a role in diabetic nephropathy? (1995) (32)
- Targeting the sphingosine kinase/sphingosine 1-phosphate pathway to treat chronic inflammatory kidney diseases. (2014) (32)
- Coordinated induction of inducible nitric oxide synthase and GTP-cyclohydrolase I is dependent on inflammatory cytokines and interferon-gamma in HaCaT keratinocytes: implications for the model of cutaneous wound repair. (1998) (32)
- Pyrrolidine dithiocarbamate differentially affects cytokine‐ and cAMP‐induced expression of group II phospholipase A2 in rat renal mesangial cells (1995) (32)
- Interleukin 1 beta and cAMP trigger the expression of GTP cyclohydrolase I in rat renal mesangial cells. (1996) (32)
- Failure of Interferon γ to Induce the Anti-Inflammatory Interleukin 18 Binding Protein in Familial Hemophagocytosis (2010) (32)
- ‘Antiflammins’: Two nonapeptide fragments of uteroglobin and lipocortin I have no phospholipase A2 ‐inhibitory and anti‐inflammatory activity (1990) (32)
- PS3, a semisynthetic beta-1,3-glucan sulfate, diminishes contact hypersensitivity responses through inhibition of L- and P-selectin functions. (2009) (32)
- A role for protein kinase C‐α in zymosan‐stimulated eicosanoid synthesis in mouse peritoneal macrophages (1993) (31)
- Sphingosine Kinase-2 Deficiency Ameliorates Kidney Fibrosis by Up-Regulating Smad7 in a Mouse Model of Unilateral Ureteral Obstruction. (2017) (31)
- Protein kinase C inhibitors potentiate angiotensin II-induced phosphoinositide hydrolysis and intracellular Ca2+ mobilization in renal mesangial cells. (1993) (31)
- Differential binding of ceramide to MEKK1 in glomerular endothelial and mesangial cells. (2004) (31)
- Molecular mechanisms of IL‐18BP regulation in DLD‐1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level (2009) (31)
- ADAM10 is expressed in human podocytes and found in urinary vesicles of patients with glomerular kidney diseases (2010) (30)
- Sphingosine Kinase1 Is Pivotal for FcεRI-Mediated Mast Cell Signaling and Functional Responses In Vitro and In Vivo (2009) (30)
- Anti-inflammatory steroids inhibit cytokine induction of nitric oxide synthase in rat renal mesangial cells. (1991) (30)
- Extracellular ATP stimulates poly(inositol phospholipid) hydrolysis and eicosanoid synthesis in mouse peritoneal macrophages in culture. (1989) (30)
- Nitric oxide and mechanisms of redox signaling. (2003) (30)
- Amplification of nitric oxide synthase expression by nitric oxide in interleukin 1beta-stimulated rat mesangial cells. (1996) (30)
- Ceramide Kinase Contributes to Proliferation but not to Prostaglandin E2 Formation in Renal Mesangial Cells and Fibroblasts (2014) (29)
- Application of IL-36 receptor antagonist weakens CCL20 expression and impairs recovery in the late phase of murine acetaminophen-induced liver injury (2015) (29)
- Biglycan- and Sphingosine Kinase-1 Signaling Crosstalk Regulates the Synthesis of Macrophage Chemoattractants (2017) (29)
- Molecular mechanisms of cyclosporin A inhibition of the cytokine-induced matrix metalloproteinase-9 in glomerular mesangial cells. (2007) (29)
- Regulatory functions of protein kinase C isoenzymes in purinoceptor signalling in mesangial cells. (1996) (29)
- Unravelling green tea's mechanisms of action: more than meets the eye. (2004) (28)
- The cytoskeletal inhibitors latrunculin A and blebbistatin exert antitumorigenic properties in human hepatocellular carcinoma cells by interfering with intracellular HuR trafficking. (2015) (28)
- Ceramide induces translocation of protein kinase C-alpha to the Golgi compartment of human embryonic kidney cells by interacting with the C2 domain. (2003) (28)
- Short-term exposure to high-pressure ventilation leads to pulmonary biotrauma and systemic inflammation in the rat. (2008) (28)
- The suppressor of cytokine signaling (SOCS)-3 determines keratinocyte proliferative and migratory potential during skin repair. (2010) (28)
- Genome-wide analysis displays marked induction of EBI3/IL-27B in IL-18-activated AML-derived KG1 cells: critical role of two kappaB binding sites in the human EBI3 promotor. (2008) (28)
- Domain-specific phosphomimetic mutation allows dissection of different protein kinase C (PKC) isotype-triggered activities of the RNA binding protein HuR. (2013) (27)
- Light-induced phosphoinositide degradation and light-induced structural alterations in the rat retina are enhanced after chronic lithium treatment. (1988) (27)
- Inhibition of erythropoietin production by phorbol ester is associated with down-regulation of protein kinase C-alpha isoenzyme in hepatoma cells. (1991) (27)
- Nitric oxide induces neutral ceramidase degradation by the ubiquitin/proteasome complex in renal mesangial cell cultures (2002) (27)
- Cross‐talk between group IIA‐phospholipase A2 and inducible NO‐synthase in rat renal mesangial cells (1999) (27)
- Non-alcoholic fatty liver disease (NAFLD) potentiates autoimmune hepatitis in the CYP2D6 mouse model. (2016) (27)
- Activation of interferon regulatory factor-3 via toll-like receptor 3 and immunomodulatory functions detected in A549 lung epithelial cells exposed to misplaced U1-snRNA (2009) (27)
- Mechanism of autoimmune hepatic fibrogenesis induced by an adenovirus encoding the human liver autoantigen cytochrome P450 2D6. (2013) (27)
- Silencing of the mRNA-binding protein HuR increases the sensitivity of colorectal cancer cells to ionizing radiation through upregulation of caspase-2. (2017) (26)
- H2S-induced thiol-based redox switches: Biochemistry and functional relevance for inflammatory diseases. (2016) (26)
- On the induction of cyclooxygenase-2, inducible nitric oxide synthase and soluble phospholipase A2 in rat mesangial cells by a nonsteroidal anti-inflammatory drug: the role of cyclic AMP. (1998) (26)
- A role for protein kinase C‐ϵ in angiotensin II stimulation of phospholipase D in rat renal mesangial cells (1993) (26)
- Increased Serum Levels of the IL‐33 Neutralizing sST2 in Limited Cutaneous Systemic Sclerosis (2015) (26)
- Upregulation of the S1P3 receptor in metastatic breast cancer cells increases migration and invasion by induction of PGE2 and EP2/EP4 activation. (2016) (26)
- Interleukin-1beta induces chronic activation and de novo synthesis of neutral ceramidase in renal mesangial cells. (2001) (26)
- A Prominent Role of Interleukin-18 in Acetaminophen-Induced Liver Injury Advocates Its Blockage for Therapy of Hepatic Necroinflammation (2018) (26)
- Heterologous desensitization of the sphingosine‐1‐phosphate receptors by purinoceptor activation in renal mesangial cells (2004) (26)
- Simultaneous and Dose Dependent Melanoma Cytotoxic and Immune Stimulatory Activity of Betulin (2015) (26)
- Desflurane differentially affects the release of proinflammatory cytokines in plasma and bronchoalveolar fluid of endotoxemic rats. (2006) (26)
- Warfarin Anticoagulation Exacerbates the Risk of Hemorrhagic Transformation after rt-PA Treatment in Experimental Stroke: Therapeutic Potential of PCC (2011) (25)
- Immunopharmacology: anti-inflammatory therapy targeting transcription factors. (1999) (25)
- Cancer-induced inflammation and inflammation-induced cancer in colon: a role for S1P lyase (2019) (25)
- The induction of cellular group II phospholipase A2 by cytokines and its prevention by dexamethasone. (1992) (25)
- Regulation of inhibitor of apoptosis expression by nitric oxide and cytokines: relation to apoptosis induction in rat mesangial cells and raw 264.7 macrophages. (2001) (25)
- Negative regulation of interleukin‐1β‐activated neutral sphingomyelinase by protein kinase C in rat mesangial cells (1998) (25)
- The S1P–S1PR Axis in Neurological Disorders—Insights into Current and Future Therapeutic Perspectives (2020) (25)
- Suppression by cyclosporin A of interleukin 1β‐induced expression of group II phospholipase A2 in rat renal mesangial cells (1997) (25)
- Lack of Interferon-γ Production Despite the Presence of Interleukin-18 During Cutaneous Wound Healing (2000) (25)
- Thiazolidinedione‐dependent activation of sphingosine kinase 1 causes an anti‐fibrotic effect in renal mesangial cells (2012) (25)
- Nitric oxide induces TIMP-1 expression by activating the transforming growth factor beta-Smad signaling pathway. (2005) (24)
- Nephrin expression is increased in anti-Thy1.1-induced glomerulonephritis in rats. (2004) (24)
- Angiotensin II stimulation of phospholipase D in rat renal mesangial cells is mediated by the AT1 receptor subtype. (1992) (24)
- Novel oxazolo-oxazole derivatives of FTY720 reduce endothelial cell permeability, immune cell chemotaxis and symptoms of experimental autoimmune encephalomyelitis in mice (2014) (24)
- Type I Interferon Supports Inducible Nitric Oxide Synthase in Murine Hepatoma Cells and Hepatocytes and during Experimental Acetaminophen-Induced Liver Damage (2017) (24)
- Interleukin 1 and tumor necrosis factor potentiate angiotensin II- and calcium ionophore-stimulated prostaglandin E2 synthesis in rat renal mesangial cells. (1990) (23)
- Rat GTP cyclohydrolase I is a homodecameric protein complex containing high-affinity calcium-binding sites. (1998) (23)
- Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1. (2010) (23)
- Identification of manganese superoxide dismutase as a NO-regulated gene in rat glomerular mesangial cells by 2D gel electrophoresis. (2003) (23)
- Nitric oxide and vascular remodeling: spotlight on the kidney. (2007) (23)
- Ceramides as Key Players in Cellular Stress Response. (2000) (23)
- Nitric oxide inhibits glomerular TGF-beta signaling via SMOC-1. (2009) (23)
- Biphasic Regulation of HMG-CoA Reductase Expression and Activity during Wound Healing and Its Functional Role in the Control of Keratinocyte Angiogenic and Proliferative Responses* (2008) (23)
- IL-18BPa:Fc cooperates with immunosuppressive drugs in human whole blood. (2003) (23)
- Effects of dexamethasone and transforming growth factor-beta 2 on group II phospholipase A2 mRNA and activity levels in interleukin 1 beta- and forskolin-stimulated mesangial cells. (1996) (23)
- Effects of homo- and heterodimeric isoforms of PDGF on signalling events in rat renal mesangial cells. (1991) (23)
- Hypoxia enhances prostaglandin synthesis in renal mesangial cell cultures. (1985) (23)
- Keratinocyte-Derived Vascular Endothelial Growth Factor Biosynthesis Represents a Pleiotropic Side Effect of Peroxisome Proliferator-Activated Receptor-γ Agonist Troglitazone but Not Rosiglitazone and Involves Activation of p38 Mitogen-Activated Protein Kinase: Implications for Diabetes-Impaired Ski (2008) (22)
- Sphingosine kinase 1 is critically involved in nitric oxide‐mediated human endothelial cell migration and tube formation (2010) (22)
- Norepinephrine and vasopressin counteract anti-inflammatory effects of isoflurane in endotoxemic rats. (2007) (22)
- Parathyroid hormone inhibition of Na+/phosphate cotransport in OK cells: intracellular [Ca2+] as a second messenger. (1989) (22)
- Inhibition of Rho modulates cytokine-induced prostaglandin E2 formation in renal mesangial cells. (2004) (22)
- Deregulated unfolded protein response in chronic wounds of diabetic ob/ob mice: a potential connection to inflammatory and angiogenic disorders in diabetes-impaired wound healing. (2014) (22)
- Pyrrolidine Dithiocarbamate Activates p38 MAPK and Protects Brain Endothelial Cells From Apoptosis: A Mechanism for the Protective Effect in Stroke? (2010) (22)
- Angiotensin II stimulation of the stress-activated protein kinases in renal mesangial cells is mediated by the angiotensin AT1 receptor subtype. (1998) (22)
- Mechanism of NaCl transport-stimulated prostaglandin formation in MDCK cells. (1987) (22)
- Identification of ceramide targets in interleukin-1 and tumor necrosis factor-alpha signaling in mesangial cells. (1998) (22)
- Differential recovery of protein kinase C-α and -ɛ isozymes after long-term phorbol ester treatment in rat renal mesangial cells (1991) (22)
- An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis. (2016) (22)
- Islet-Expressed CXCL10 Promotes Autoimmune Destruction of Islet Isografts in Mice With Type 1 Diabetes (2016) (22)
- Angiotensin II type 1-receptor antagonism prevents type IIA secretory phospholipase A2-dependent lipid peroxidation. (2007) (22)
- Uptake of neutrophil-derived Ym1 protein distinguishes wound macrophages in the absence of interleukin-4 signaling in murine wound healing. (2014) (21)
- Downregulation of SPARC expression is mediated by nitric oxide in rat mesangial cells and during endotoxemia in the rat. (2000) (21)
- PAX2 Regulates ADAM10 Expression and Mediates Anchorage-Independent Cell Growth of Melanoma Cells (2011) (21)
- Cellular mechanisms of bradykinin-induced hyperpolarization in renal epitheloid MDCK-cells. (1991) (21)
- Comparison of different tumour promoters and bryostatin 1 on protein kinase C activation and down-regulation in rat renal mesangial cells. (1994) (21)
- IFN-gamma Impairs Release of IL-8 by IL-1beta-stimulated A549 Lung Carcinoma Cells (2008) (20)
- Upregulation of group IB secreted phospholipase A(2) and its M-type receptor in rat ANTI-THY-1 glomerulonephritis. (2006) (20)
- Anti-CD3/Anti-CXCL10 Antibody Combination Therapy Induces a Persistent Remission of Type 1 Diabetes in Two Mouse Models (2015) (20)
- RNA-dependent association with myosin IIA promotes F-actin-guided trafficking of the ELAV-like protein HuR to polysomes (2013) (20)
- ADAM15 expression is downregulated in melanoma metastasis compared to primary melanoma. (2010) (20)
- Role of wound macrophages in skin flap loss or survival in an experimental diabetes model (2010) (20)
- Ceramide Kinase Is Upregulated in Metastatic Breast Cancer Cells and Contributes to Migration and Invasion by Activation of PI 3-Kinase and Akt (2020) (20)
- Modulation of tissue plasminogen activator and plasminogen activator inhibitor-1 by transforming growth factor-beta in human retinal glial cells. (2002) (20)
- Superoxide potently induces ceramide formation in glomerular endothelial cells. (2001) (20)
- Pharmacological properties of five diclofenac metabolites identified in human plasma (1991) (20)
- Potentiation of TNF-α–Stimulated Group IIA Phospholipase A2 Expression by Peroxisome Proliferator–Activated Receptor α Activators in Rat Mesangial Cells (2002) (20)
- Endothelial Cell Cystathionine γ‐Lyase Expression Level Modulates Exercise Capacity, Vascular Function, and Myocardial Ischemia Reperfusion Injury (2020) (20)
- FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase (2015) (19)
- Sphingosine kinase 2 deficient mice exhibit reduced experimental autoimmune encephalomyelitis: Resistance to FTY720 but not ST-968 treatments (2016) (19)
- Interferon-gamma induces expression of interleukin-18 binding protein in fibroblast-like synoviocytes. (2003) (19)
- Nitric oxide differentially regulates pro‐ and anti‐angiogenic markers in DLD‐1 colon carcinoma cells (2004) (19)
- NaCl transport stimulates prostaglandin release in cultured renal epithelial (MDCK) cells. (1986) (19)
- Attenuation of the ELAV1-like protein HuR sensitizes adenocarcinoma cells to the intrinsic apoptotic pathway by increasing the translation of caspase-2L (2014) (19)
- Differential effect of dexamethasone on interleukin 1β‐ and cyclic AMP‐triggered expression of GTP cyclohydrolase I in rat renal mesangial cells (1997) (19)
- Cellular signalling in the kidney: the role of inositol lipids. (1989) (19)
- Erythropoietin is more than just a promoter of erythropoiesis. (2004) (19)
- Small molecule CXCR3 antagonist NIBR2130 has only a limited impact on type 1 diabetes in a virus‐induced mouse model (2011) (18)
- Glucocorticoids protect renal mesangial cells from apoptosis by increasing cellular sphingosine-1-phosphate. (2010) (18)
- Ncf1 Provides a Reactive Oxygen Species-Independent Negative Feedback Regulation of TLR9-Induced IL-12p70 in Murine Dendritic Cells1 (2009) (18)
- Hypoxia increases group IIA phospholipase A(2) expression under inflammatory conditions in rat renal mesangial cells. (2005) (18)
- Influence of the vitamin D plasma level and vitamin D‐related genetic polymorphisms on the immune status of patients with type 1 diabetes: a pilot study (2013) (18)
- Pharmacology of the sphingosine-1-phosphate signalling system. (2013) (18)
- Dissociated glucocorticoids equipotently inhibit cytokine- and cAMP-induced matrix degrading proteases in rat mesangial cells. (2005) (18)
- Interleukin 1‐ and tumor necrosis factor‐stimulation of prostaglandin E2 synthesis in MDCK cells, and potentiation of this effect by cycloheximide (1990) (18)
- Downregulation of the S1P Transporter Spinster Homology Protein 2 (Spns2) Exerts an Anti-Fibrotic and Anti-Inflammatory Effect in Human Renal Proximal Tubular Epithelial Cells (2018) (18)
- Coexpression of inducible NO synthase and soluble guanylyl cyclase in colonic enterocytes: a pathophysiologic signaling pathway for the initiation of diarrhea by gram‐negative bacteria? (1998) (17)
- Platelet, not endothelial, P-selectin expression contributes to generation of immunity in cutaneous contact hypersensitivity. (2010) (17)
- Angiotensin II binding sites on micro-organisms contaminating cell cultures (1993) (17)
- Inhibition of IRES-dependent translation of caspase-2 by HuR confers chemotherapeutic drug resistance in colon carcinoma cells (2018) (17)
- Upregulation of ABC transporters contributes to chemoresistance of sphingosine 1-phosphate lyase-deficient fibroblasts (2015) (17)
- Redox Signaling in Mesangial Cells (2003) (17)
- Potentiation of cytokine induction of group IIA phospholipase A2 in rat mesangial cells by ATP and adenosine via the A2A adenosine receptor (2001) (17)
- FTY720 suppresses interleukin‐1β‐induced secretory phospholipase A2 expression in renal mesangial cells by a transcriptional mechanism (2007) (17)
- Serum sphingolipids predict de novo hepatocellular carcinoma in hepatitis C cirrhotic patients with sustained virologic response (2019) (17)
- Sphingosine kinase 2 deficiency increases proliferation and migration of renal mouse mesangial cells and fibroblasts (2015) (17)
- Activated protein C downregulates p38 mitogen-activated protein kinase and improves clinical parameters in an in-vivo model of septic shock (2007) (17)
- Protein kinase C in the rat retina: immunocharacterization of calcium-independent δ, ϵ and ζ isoenzymes (1992) (17)
- Tristetraprolin regulation of interleukin-22 production (2015) (16)
- Platelet-derived growth factor stimulates de-novo synthesis of mitogen-activated protein kinase in renal mesangial cells. (1995) (16)
- Defective IL-23/IL-17 Axis Protects p47phox−/− Mice from Colon Cancer (2017) (16)
- Persistence of HCV in Acutely-Infected Patients Depletes C24-Ceramide and Upregulates Sphingosine and Sphinganine Serum Levels (2016) (16)
- The HIV protease inhibitor ritonavir synergizes with butyrate for induction of apoptotic cell death and mediates expression of heme oxygenase‐1 in DLD‐1 colon carcinoma cells (2004) (16)
- Blood ceramides as novel markers for renal impairment in systemic lupus erythematosus. (2019) (16)
- Tight Spatial and Temporal Control in Dynamic Basal to Distal Migration of Epithelial Inflammatory Responses and Infiltration of Cytoprotective Macrophages Determine Healing Skin Flap Transplants in Mice (2009) (16)
- Increase of cystathionine-γ-lyase (CSE) during late wound repair: Hydrogen sulfide triggers cytokeratin 10 expression in keratinocytes. (2019) (16)
- Sphingosine-1-Phosphate Receptor 5 Modulates Early-Stage Processes during Fibrogenesis in a Mouse Model of Systemic Sclerosis: A Pilot Study (2017) (15)
- Effects of high glucose on cytokine-induced nerve growth factor (NGF) expression in rat renal mesangial cells. (2003) (15)
- Susceptibility of interleukin 1- and tumour necrosis factor-induced prostaglandin E2 and phospholipase A2 release from rat renal mesangial cells to different drugs (1989) (15)
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- Downregulation of integrin-linked kinase mRNA expression by nitric oxide in rat glomerular mesangial cells. (2001) (15)
- Systematic analysis highlights the key role of TLR2/NF-kappaB/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates. (2008) (15)
- Inhibition of renin secretion by platelet activating factor (acetylglyceryl ether phosphorylcholine) in cultured rat renal juxtaglomerular cells. (1985) (15)
- Characterization of cholesterol homeostasis in sphingosine-1-phosphate lyase-deficient fibroblasts reveals a Niemann-Pick disease type C-like phenotype with enhanced lysosomal Ca2+ storage (2017) (15)
- Inhibition of cyclooxygenase‐1 and ‐2 activity in keratinocytes inhibits PGE2 formation and impairs vascular endothelial growth factor release and neovascularisation in skin wounds (2017) (15)
- Feedback regulation of extracellular ATP-stimulated phosphoinositide hydrolysis by protein kinase C-alpha in bovine glomerular endothelial cells. (1997) (15)
- Cellular mechanisms of adrenaline-induced hyperpolarization in renal epitheloid MDCK cells. (1991) (15)
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- Vitamin D Supplementation Enhances C18(dihydro)ceramide Levels in Type 2 Diabetes Patients (2017) (14)
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- Mechanisms of Rapid Induction of Interleukin-22 in Activated T Cells and Its Modulation by Cyclosporin A* (2011) (14)
- Activation-Induced Cell Death of Dendritic Cells Is Dependent on Sphingosine Kinase 1 (2016) (14)
- Sphingosine Kinase 2 Modulates Retinal Neovascularization in the Mouse Model of Oxygen-Induced Retinopathy. (2018) (14)
- Mechanisms of Suppression of Inducible Nitric-oxide Synthase (iNOS) Expression in Interferon (IFN)-γ-stimulated RAW 264.7 Cells by Dexamethasone (1997) (14)
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- Nitric oxide upregulates induction of PDGF receptor-alpha expression in rat renal mesangial cells and in anti-Thy-1 glomerulonephritis. (2005) (14)
- PPARγ agonists upregulate sphingosine 1-phosphate (S1P) receptor 1 expression, which in turn reduces S1P-induced [Ca(2+)]i increases in renal mesangial cells. (2013) (13)
- Eukaryotic expression of the broad‐spectrum chemokine receptor antagonist vMIP‐II and its effects on T‐cell function in vitro and in vivo (2006) (13)
- Transforming growth factor beta 2 inhibits interleukin 1 beta- and tumour necrosis factor alpha-induction of nitric oxide synthase in rat renal mesangial cells. (1991) (13)
- Angiogenic response pattern during normal and impaired skin flap re-integration in mice: a comparative study. (2014) (13)
- CXCL9 Causes Heterologous Desensitization of CXCL12-Mediated Memory T Lymphocyte Activation (2013) (13)
- Mechanisms of dexamethasone-mediated inhibition of cAMP-induced tPA expression in rat mesangial cells. (2002) (13)
- Effect of synthetic atrial natriuretic peptide on rat renal juxtaglomerular cells. (1986) (13)
- Translocation of protein kinase C isoenzymes by elevated extracellular Ca2+ concentration in cells from a human giant cell tumor of bone. (1995) (13)
- Interleukin 1 beta and tumour necrosis factor alpha induce a macrophage-type of nitric oxide synthase in rat renal mesangial cells. (1992) (13)
- Transforming growth factor beta 2 stimulates acute and chronic activation of the mitogen-activated protein kinase cascade in rat renal mesangial cells. (1994) (12)
- Junctional adhesion molecules JAM-B and JAM-C promote autoimmune-mediated liver fibrosis in mice. (2018) (12)
- Phospholipase A2 in mesangial cells: control mechanisms and functional importance. (1997) (12)
- Cerivastatin inhibits proliferation of interleukin-1 beta-induced rat mesangial cells by enhanced formation of nitric oxide. (2004) (12)
- Identification of the LIM kinase-1 as a ceramide-regulated gene in renal mesangial cells. (2002) (12)
- A Sphingosine 1-Phosphate Gradient Is Linked to the Cerebral Recruitment of T Helper and Regulatory T Helper Cells during Acute Ischemic Stroke (2020) (12)
- Light evoked inositol trisphosphate release in the rat retina in vitro. (1993) (12)
- Interferon-Beta Increases Plasma Ceramides of Specific Chain Length in Multiple Sclerosis Patients, Unlike Fingolimod or Natalizumab (2016) (12)
- Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis (2016) (12)
- Proliferative mechanisms in kidney cells. (1995) (11)
- Transforming growth factor β2 (TGF-β2)-induced connective tissue growth factor (CTGF) expression requires sphingosine 1-phosphate receptor 5 (S1P5) in human mesangial cells. (2015) (11)
- Inflammation-Induced Mucosal KYNU Expression Identifies Human Ileal Crohn’s Disease (2020) (11)
- Control of Phospholipase A2 Gene Expression (1997) (11)
- Cytoskeleton-Dependent Transport as a Potential Target for Interfering with Post-transcriptional HuR mRNA Regulons (2016) (11)
- A new class of inhibitors of secretory phospholipase A2: enolized 1,3-dioxane-4,6-dione-5-carboxamides (1994) (11)
- Inhibition of lipopolysaccharide/ATP-induced release of interleukin-18 by KN-62 and glyburide. (2003) (11)
- Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge (2020) (11)
- Interleukin-1 inhibits angiotensin II-stimulated protein kinase B pathway in renal mesangial cells via the inducible nitric oxide synthase. (2002) (11)
- Modulation of cytokine-induced expression of secretory phospholipase A2-type IIA by protein kinase C in rat renal mesangial cells. (1999) (11)
- Sphingosylphosphorylcholine acts in an anti-inflammatory manner in renal mesangial cells by reducing interleukin-1β-induced prostaglandin E2 formation Published, JLR Papers in Press, June 25, 2007. (2007) (10)
- Expanding extracellular zinc beyond levels reflecting the albumin-bound plasma zinc pool potentiates the capability of IL-1beta, IL-18, and IL-12 to Act as IFN-gamma-inducing factors on PBMC. (2007) (10)
- Inhibition of NFκB‐mediated pro‐inflammatory gene expression in rat mesangial cells by the enolized 1,3‐dioxane‐4,6‐dione‐5‐carboxamide, CGP‐43182 (2000) (10)
- Fingolimod targeting protein phosphatase 2A differently affects IL‐33 induced IL‐2 and IFN‐γ production in CD8+ lymphocytes (2016) (10)
- Tissue Cytokine IL-33 Modulates the Cytotoxic CD8 T Lymphocyte Activity During Nutrient Deprivation by Regulation of Lineage-Specific Differentiation Programs (2019) (10)
- Transforming growth factor-β2 inhibits interleukin 1β-induced expression of inducible nitric oxide synthase in rat renal mesangial cells (1997) (10)
- Blockade but Not Overexpression of the Junctional Adhesion Molecule C Influences Virus-Induced Type 1 Diabetes in Mice (2013) (9)
- Identification of TRIM25 as a Negative Regulator of Caspase-2 Expression Reveals a Novel Target for Sensitizing Colon Carcinoma Cells to Intrinsic Apoptosis (2019) (9)
- Inhibition by tetranactin of interleukin 1β‐ and cyclic AMP‐induced nitric oxide synthase expression in rat renal mesangial cells (1996) (9)
- Modulatory role of platelet-derived growth factor on cytokine-induced nerve growth factor synthesis in rat glomerular mesangial cells. (1995) (9)
- Cytokine regulation of Group II phospholipase A2 expression in glomerular mesangial cells (2005) (9)
- Loss of sphingosine kinase 2 enhances Wilm's tumor suppressor gene 1 and nephrin expression in podocytes and protects from streptozotocin-induced podocytopathy and albuminuria in mice. (2021) (9)
- Alterations of the Ceramide Metabolism in the Peri-Infarct Cortex Are Independent of the Sphingomyelinase Pathway and Not Influenced by the Acid Sphingomyelinase Inhibitor Fluoxetine (2015) (9)
- Cooperation between the bacterial‐derived short‐chain fatty acid butyrate and interleukin‐22 detected in human Caco2 colon epithelial/carcinoma cells (2017) (9)
- Potentiation of TNF-alpha-stimulated group IIA phospholipase A(2) expression by peroxisome proliferator-activated receptor alpha activators in rat mesangial cells. (2002) (9)
- [Measles in 2010. Knowledge and vaccination status of medical students]. (2011) (9)
- Novel compounds with dual S1P receptor agonist and histamine H3 receptor antagonist activities act protective in a mouse model of multiple sclerosis (2021) (9)
- Nuclear Translocation of SGPP-1 and Decrease of SGPL-1 Activity Contribute to Sphingolipid Rheostat Regulation of Inflammatory Dendritic Cells (2017) (8)
- Comparing hemodynamics, blood gas analyses and proinflammatory cytokines in endotoxemic and severely septic rats. (2011) (8)
- Computer‐aided analysis of cell interactions under dynamic flow conditions (2009) (8)
- The Pathophysiology of H2S in Renal Glomerular Diseases (2022) (8)
- Design, Synthesis, and Structure-Activity Relationship Studies of Dual Inhibitors of Soluble Epoxide Hydrolase and 5-Lipoxygenase. (2020) (8)
- Potentiation by light of lithium-induced retinal injury in rats. (1987) (7)
- S1P d20:1, an endogenous modulator of S1P d18:1/S1P2‐dependent signaling (2020) (7)
- Controlling the cytokine storm by insulin: glycogen synthase kinase-3 as a target in systemic inflammation. (2006) (7)
- Cyclic AMP increases rat inhibitor of apoptosis protein (RIAP1) mRNA in renal mesangial cells. (2002) (7)
- Enhanced expression of group IIA secreted phospholipase A2 by elevated glucose levels in cytokine-stimulated rat mesangial cells and in kidneys of diabetic rats. (2005) (7)
- Epigenetic regulation by CpG methylation splits strong from retarded IFNγ-induced IL-18BP in epithelial versus monocytic cells. (2018) (7)
- Impact of Moderna mRNA-1273 Booster Vaccine on Fully Vaccinated High-Risk Chronic Dialysis Patients after Loss of Humoral Response (2022) (7)
- Modulation of IL‐33/ST2‐TIR and TLR Signalling Pathway by Fingolimod and Analogues in Immune Cells (2014) (7)
- 5-Hydroxytryptamine 5-HT1B receptors inhibiting cyclic AMP accumulation in rat renal mesangial cells (2004) (7)
- Nitric Oxide Signalling with a Special Focus on Lipid-Derived Mediators (2003) (7)
- Though Active on RINm5F Insulinoma Cells and Cultured Pancreatic Islets, Recombinant IL-22 Fails to Modulate Cytotoxicity and Disease in a Protocol of Streptozotocin-Induced Experimental Diabetes (2016) (7)
- Subcellular distribution of FTY720 and FTY720-phosphate in immune cells – another aspect of Fingolimod action relevant for therapeutic application (2015) (7)
- Identification of the Fra-1 transcription factor in healing skin flaps transplants: a potential role as a negative regulator of VEGF release from keratinocytes. (2012) (7)
- Extracellular ATP and UTP activation of phospholipase D is mediated by protein kinase C-epsilon in rat renal mesangial cells. (1993) (7)
- Low Serum Levels of (Dihydro-)Ceramides Reflect Liver Graft Dysfunction in a Real-World Cohort of Patients Post Liver Transplantation (2018) (7)
- Gasotransmitter synthesis and signalling in the renal glomerulus. Implications for glomerular diseases. (2020) (7)
- Thr308 determines Akt1 nuclear localization in insulin-stimulated keratinocytes. (2008) (7)
- Interleukin‐1β inhibits ATP‐induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide (2003) (7)
- [Pharmacogenetics and pharmacogenomics of methotrexate. Current status and novel aspects]. (2011) (6)
- Serum sphingolipid levels associate with upcoming virologic events and HBV genotype D in a cohort of patients with HBeAg-negative HBV infection (2018) (6)
- Activation of renal profibrotic TGFβ controlled signaling cascades by calcineurin and mTOR inhibitors. (2018) (6)
- Beta adrenoceptor blockade ameliorates impaired glucose tolerance and alterations of the cerebral ceramide metabolism in an experimental model of ischemic stroke (2018) (6)
- Platelet-derived growth factor and fibroblast growth factor differentially regulate interleukin 1β- and cAMP-induced group II phospholipase A2 expression in rat renal mesangial cells (1998) (6)
- Sorafenib Treatment and Modulation of the Sphingolipid Pathway Affect Proliferation and Viability of Hepatocellular Carcinoma In Vitro (2020) (6)
- Consistent alteration of chain length-specific ceramides in human and mouse fibrotic kidneys. (2020) (6)
- Vitamin D effects on sphingosine 1-phosphate signaling and metabolism in monocytes from type 2 diabetes patients and controls (2019) (6)
- Diurnal regulation of sphingolipids in blood. (2019) (6)
- Signalling pathways of nitric oxide. (2000) (6)
- Simultaneous measurment of Ca2+ transients and shape changes in rat mesangial cells to evaluate the effects of recombinant human interleukin-1β (1992) (5)
- Hypoxia and lipid signaling (2006) (5)
- Regulatory functions of protein kinase c in glomerular mesangial cells (1990) (5)
- Serum Sphingosine‐1‐Phosphate Is Decreased in Patients With Acute‐on‐Chronic Liver Failure and Predicts Early Mortality (2020) (5)
- The sphingosine kinase 1 activator, K6PC-5, attenuates Ebola virus infection (2021) (5)
- Cytokine production by leukocytes of Papillon–Lefèvre syndrome patients in whole blood cultures (2012) (5)
- cAMP potentiates interleukin 1- and tumor necrosis factor-stimulated phospholipase A2 secretion from rat renal mesangial cells (1990) (5)
- H2O2 inhibits BCR-dependent immediate early induction of EBV genes in Burkitt's lymphoma cells. (2009) (5)
- C6 Ceramide (d18:1/6:0) as a Novel Treatment of Cutaneous T Cell Lymphoma (2021) (5)
- Hypothermia Promotes Interleukin-22 Expression and Fine-Tunes Its Biological Activity (2017) (5)
- Interleukin-1 beta and transforming growth factor-beta 2 enhance cytosolic high-molecular-mass phospholipase A2 activity and induce prostaglandin E2 formation in rat mesangial cells. (1992) (5)
- Transforming growth factor-beta 2 inhibits interleukin 1 beta-induced expression of inducible nitric oxide synthase in rat renal mesangial cells. (1997) (5)
- Interleukin-1 beta-induced cytosolic phospholipase A2 activity and protein synthesis is blocked by dexamethasone in rat mesangial cells. (1993) (4)
- Cytokines induce protein kinase A-mediated signalling by a redox-dependent mechanism in rat renal mesangial cells. (2015) (4)
- Regulatory functions of protein kinase C isoenzymes in glomerular mesangial cells. (1994) (4)
- Differential recovery of protein kinase C-alpha and -epsilon isozymes after long-term phorbol ester treatment in rat renal mesangial cells. (1991) (4)
- [Lithium-induced lesions in the rat retina--potentiation by light]. (1988) (4)
- Molecular mechanisms of PDGF-AA expression induced by the dsRNA-mimetic poly (I:C) and IL-18. (2013) (4)
- A role for protein kinase C-epsilon in angiotensin II stimulation of phospholipase D in rat renal mesangial cells. (1993) (4)
- Enhanced CXCR4 Expression of Human CD8Low T Lymphocytes Is Driven by S1P4 (2021) (4)
- S1P Lyase siRNA Dampens Malignancy of DLD-1 Colorectal Cancer Cells. (2020) (4)
- Validation of highly selective sphingosine kinase 2 inhibitors SLM6031434 and HWG-35D as effective anti-fibrotic treatment options in a mouse model of tubulointerstitial fibrosis. (2020) (4)
- Interleukin-1 beta, tumor necrosis factor and forskolin stimulate the synthesis and secretion of group II phospholipase A2 in rat mesangial cells. (1991) (4)
- Upregulation of matrilin‐2 expression in murine hepatic stellate cells during liver injury has no effect on fibrosis formation and resolution (2015) (3)
- The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions (2022) (3)
- Immunocharacterization of delta- and zeta-isoenzymes of protein kinase C in rat renal mesangial cells. (1992) (3)
- Mouse Liver Compensates Loss of Sgpl1 by Secretion of Sphingolipids into Blood and Bile (2021) (3)
- The atypical sphingosine 1‐phosphate variant, d16:1 S1P, mediates CTGF induction via S1P2 activation in renal cell carcinoma (2022) (3)
- Nitric oxide mediates prolyl hydroxylase 3 expression in mesangial cells and in glomerulonephritis (2017) (3)
- Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator. (2011) (3)
- Reciprocal abrogation of PKM isoforms: contradictory outcomes and differing impact of splicing signal on CRISPR/Cas9 mediates gene editing in keratinocytes (2022) (3)
- Downregulation of Cytokine-Induced Synthesis and Secretion of Group II Phospholipase A2 (1997) (3)
- CERAMIDE-BINDING AND ACTIVATION DEFINES PROTEIN KINASE c-Raf AS A CERAMIDE ACTIVATED PROTEIN KINASE (1996) (3)
- Effect of cell density on growth regulation of human glomerular epithelial cells. Inhibition of growth by dbcAMP and cAMP-elevating agonists. (1991) (3)
- Betulin - a plant-derived cytostatic drug - enhances antitumor immune response (2014) (3)
- Large induction of the chemokine RANTES during cutaneous wound repair A regulatory role for nitric oxide in keratinocyte-derived RANTES expression (2000) (3)
- Effects of dexamethasone and transforming growth factor-β 2 on group II phospholipase A 2 mRNA and activity levels in interleukin 1 β-and forskolin-stimulated mesangial cells (1996) (2)
- Oxidative Stress Injury in Glomerular Mesangium (2011) (2)
- Interferon-c induces expression of interleukin-18 binding protein in fibroblast-like synoviocytes (2003) (2)
- Renal Mesangial Cells Isolated from Sphingosine Kinase 2 Transgenic Mice Show Reduced Proliferation and are More Sensitive to Stress-Induced Apoptosis (2018) (2)
- A role for protein kinase C-alpha in zymosan-stimulated eicosanoid synthesis in mouse peritoneal macrophages. (1993) (2)
- NOS in Mesangial Cells: Physiological and Pathophysiological Roles (1997) (2)
- Erythropoietin production in cultures of rat renal mesangial cells. (1986) (2)
- Tumor necrosis factor-a and lipopolysaccharide induce apoptotic cell death in bovine glomerular endothelial cells (2015) (2)
- Recuperation of Vascular Homeostasis. (2021) (2)
- Nitric Oxide Inhibits Glomerular TGF- Signaling via SMOC-1 (2009) (2)
- Sphingosine 1-Phosphate Receptor 5 (S1P5) Knockout Ameliorates Adenine-Induced Nephropathy (2022) (2)
- Nitric Oxide and Gene Expression (2005) (2)
- The Bologna agreement is not suitable for medical education: a German view (2010) (2)
- Erratum: IL-1 family nomenclature (2011) (2)
- A heterogeneous Ly-6B2+ leukocyte population consists of yet undescribed iNOS-expressing cell types in murine skin wounds. (2018) (2)
- Interleukin 1 β and cAMP trigger the expression of GTP cyclohydrolase I in rat renal mesangial cells (1996) (2)
- Effects of adenovirus‐induced hepatocyte damage on chronic bile duct inflammation in a sclerosing cholangitis mouse model (2019) (2)
- Downregulation of sphingosine 1-phosphate (S1P) receptor 1 by dexamethasone inhibits S1P-induced mesangial cell migration (2015) (1)
- Lymphotoxin α, a novel target of posttranscriptional gene regulation by HuR in HepG2 cells (2015) (1)
- autocrine loop involving secreted phospholipase A2 and PPARα activation (2003) (1)
- Regulation of Intracellular Calcium in Cultured Renal Epithelioid (MDCK-) Cells (1990) (1)
- Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells (2022) (1)
- National survey of evaluation practices and performance-guided resource allocation at German medical schools (2019) (1)
- Phospholipases A2 and Prostaglandin Formation in Rat Glomerular Mesangial Cells (1994) (1)
- The glomerular cell: source and target of various mediators. (1997) (1)
- Guanine Nucleotide Regulatory Protein Couples Angiotensin II Receptors to Phospholipase C in Mesangial Cells (1987) (1)
- 47 Interleukin-22 in sepsis (2008) (1)
- A murine cellular model of necroinflammation displays RAGE‐dependent cytokine induction that connects to hepatoma cell injury (2020) (1)
- Correction for Doller et al., “Tandem Phosphorylation of Serines 221 and 318 by Protein Kinase Cδ Coordinates mRNA Binding and Nucleocytoplasmic Shuttling of HuR” (2017) (1)
- Protein kinase C in the rat retina: immunocharacterization of calcium-independent delta, epsilon and zeta isoenzymes. (1992) (1)
- The dsRNA-mimetic poly (I:C) and IL-18 synergize for IFNgamma and TNFalpha expression. (2009) (1)
- Regulation of GTP Cyclohydrolase I by Estrogen (2002) (1)
- Cytokine regulation of nitric oxide synthase expression in glomerular mesangial cells. (1994) (1)
- Regulation of 14 kDa Group II PLA2 in Rat Mesangial Cells (1995) (1)
- Simultaneous registration of Ca2+ transients and volume changes in rat mesangial cells: Evaluation of the effects of protein kinase C down-regulation (1992) (1)
- Expression of Ubiquitin Carboxy-Terminal Hydrolase-L1 in Photocoagulated Human Retinal Pigment Epithelial Cells (2007) (1)
- Dynamic interaction between sphingolipid enzymes, S1P and inflammatory cytokine regulation in dendritic cells (2014) (0)
- Rat Mesangial Cells and cAMP in β Synthase Gene Expression by IL-1 Molecular Mechanisms of Inducible Nitric Oxide Pfeilschifter (1998) (0)
- Retraction: Sphingosine Kinase1 Is Pivotal for Fc"RI-Mediated Mast Cell Signaling and Functional Responses In Vitro and In Vivo (2012) (0)
- [Adhesion molecules]. (2000) (0)
- PP27 - Proteomic analysis of cysteine persulfides in hydrogen sulfide-dependent signaling (2015) (0)
- Cerivastatin enhanced mRNA and protein expression of the inducible NO synthase in rat mesangial cells (2001) (0)
- Application of pseudotyped virus particles to monitor Ebola virus and SARS-CoV-2 viral entry in human cell lines (2021) (0)
- Expression of Nox1 and formation of reactive oxygen species is attenuated by nitric oxide in rat mesangial cells. (2006) (0)
- p47phox and its potential redox independent role in TLR signalling (2007) (0)
- P0087 : Low serum C24 ceramide is predictive of hepatic decompensation and poor overall survival in liver cirrhosis (2015) (0)
- Interferon-α curbs production of interleukin-22 by human peripheral blood mononuclear cells exposed to live Borrelia burgdorferi (2015) (0)
- The role of serum sphingolipids as potential biomarkers of non‐response to direct acting antiviral therapy in chronic hepatitis C virus infection (2022) (0)
- Protein in Response to IFN-Expression and Release of IL-18 Binding (2001) (0)
- Hydrogen Sulfide Modulates Endothelial–Mesenchymal Transition in Heart Failure (2022) (0)
- Additional Mode of Action? Fingolimod Inhibits the IL-33 Induced IFN-γ Formation in CD8+ and Affects the Formation of Bioactive Sphingolipids in Patients with Multiple Sclerosis (P5.291) (2016) (0)
- P 05 . 03 BCA-1 / CXCL 13 Expression Is Associated with CXCR 5 Positive B Cell Cluster Formation in Acute Renal Transplant Rejection (2004) (0)
- Opposite role for the chemokines CCL5 (RANTES) and CXCL3 (IP-10) in the development of autoimmune liver disease in the CYP2D6 mouse model (2013) (0)
- P582 Insights on the sphingolipid profile in patients with short bowel syndrome and consecutive intestinal failure (2021) (0)
- [A short summary. The history of glucocorticoids]. (2003) (0)
- P564L-cystathionine metabolism by cystathionine gamma lyase generates H2S to preserve endothelial cell function and decelerate atherosclerosis development in humans (2018) (0)
- Immunomodulation via TLR3/IRF3 by misplaced U1-snRNA as detected in human A549 lung epithelial cells (2009) (0)
- Role of protein kinase C in homologous desensitization of angiotensin II-induced phosphoinositide hydrolysis in rat renal mesangial cells (1988) (0)
- Keratinocyte-derived VEGF biosynthesis represents a pleiotropic side effect of PPAR γ agonist troglitazone but not rosiglitazone and involves activation of p 38 MAPK : implications for diabetes-impaired skin repair (2008) (0)
- Spatiotemporal dynamics of brain activation in multiple sclerosis patients and healthy control subjects : A TMS-EEG study (2014) (0)
- Risk perception and influenza vaccination coverage among medical and dental students (2009) (0)
- Induction of hepatic fibrosis by an adenovirus encoding the human liver autoantigen cytochrome P450 2D6 (2013) (0)
- Vasoconstrictor stimulated polyphosphoinositide metabolism and prostaglandin synthesis in renal mesangial cells (1986) (0)
- Chapter 5 Pathogenesis of Renal Diseases: Renal Cell Response to Injury (2007) (0)
- Matrix‐metabolizing enzymes as prime targets of redox regulation by nitric oxide (2004) (0)
- Loss of S1P Lyase Expression in Human Podocytes Causes a Reduction in Nephrin Expression That Involves PKCδ Activation (2023) (0)
- P110 Identification of the tryptophan metabolite 3-hydroxyanthranilic acid as a novel tool for the differentiation of Crohn’s disease phenotypes (2020) (0)
- ROS-independent regulation of TLR9-induced IL-12p70 by Ncf in murine dendritic cells (2008) (0)
- Possible role of protein kinase C-c isoenzyme in inhibition of interleukin 1, induction of nitric oxide synthase in rat renal mesangial cells (2005) (0)
- Co-ordinate Expression of GTP Cyclohydrolase I and Inducible Nitric Oxide Synthase in Rat Mesangial Cells (1995) (0)
- ResearchADAM 10 is expressed in human podocytes and found in urinary vesicles of patients with glomerular kidney diseases (2015) (0)
- Short communication IL-18BPa:Fc cooperates with immunosuppressive drugs in human whole blood (2003) (0)
- P0335 : Serum long chain ceramides, sphingosine and sphingosine-1-phosphate as novel diagnostic markers in patients with hepatocellular carcinoma (2015) (0)
- Subject Index Vol. 37, 2005 (2005) (0)
- Availability in Inflammatory Macrophages Oxide Synthase by IL-13 and Arginine Translational Control of Inducible Nitric (2003) (0)
- The Sphingosine Kinase-1 Activator, K6PC-5, Attenuates the Ebola Virus Infection and the Virus Induced Cell Death (2020) (0)
- In dendritic cells Toll-like receptor-dependent induction of IL-12p70 is accompanied by a profound down regulation of sphingosine-1-phosphate lyase mRNA (P1348) (2013) (0)
- Inhibition of polyphosphoinositide breakdown and prostaglandin synthesis in rat mesangial cells by islet-activating protein (1986) (0)
- Protein kinase C isoenzymes in the rat retina: Immunocharacterization of calcium independent subtypes (1992) (0)
- Activation-induced cell death in GM-CSF differentiated dendritic cells is dependent on Sphingosine kinase 1 (2016) (0)
- Expression of PKM2 in wound keratinocytes is coupled to angiogenesis during skin repair in vivo and in HaCaT keratinocytes in vitro (2023) (0)
- Cross-Regulation of the Cellular Redox System, Oxygen, and Sphingolipid Signalling (2023) (0)
- Cytokine production by leukocytes of Papillon–Lefèvre syndrome patients in whole blood cultures (2011) (0)
- Lipid signalling - Ample opportunitites for novel drug targets (2009) (0)
- Nitric oxide mediates prolyl hydroxylase 3 expression in mesangial cells and in glomerulonephritis (2017) (0)
- Lymphocyte Activation of CXCL12-Mediated Memory T CXCL9 Causes Heterologous Desensitization (2013) (0)
- Tyrosine Phosphatase Inhibition by Nitric Oxide: The Role of Cyclic GMP and Mitogen-Activated Protein Kinase Activation Rapid and Delayed p42/p44 (1998) (0)
- Lipid mediators in redox signaling (2006) (0)
- Contents, Vol. 64,1993 (1993) (0)
- Proteomic Analysis of Mesangial Cells (2009) (0)
- Acknowledgement to Referees (1999) (0)
- Role of Phospholipases A2 Inflammation (1999) (0)
- Dendritic cells as key regulators in inflammation exhibit differential and sequential regulation of interleukin-23 subunit expression (2007) (0)
- Contents Vol. 37, 2005 (2005) (0)
- Transforming growth factor-b 2 inhibits interleukin 1b-induced expression of inducible nitric oxide synthase in rat renal mesangial cells (1997) (0)
- FTY720 and two novel butterfly derivatives exert a general anti-inflammatory potential by reducing immune cell adhesion to endothelial cells through activation of S1P3 and phosphoinositide 3-kinase (2015) (0)
- No activates TIMP-1 expression in glomerular mesangial cells via activation of TGFbeta-SMAD signaling cascades (2004) (0)
- P075 Inflammation-induced cancer vs. cancer-induced inflammation is dependent on S1P lyase (2018) (0)
- Relevance of leptin for cutaneous wound healing (2008) (0)
- REVIEW INDUCIBLE NO SYNTHASE: ROLE IN CELLULAR SIGNALLING (1999) (0)
- The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions (2022) (0)
- Kinase Pathways Activation of the Mitogen-Activated Protein B and Activating Protein-1 and Involves κ NF-Cells Is Mediated by Increased Activities of Superoxide in Rat Glomerular Mesangial Metalloproteinase-9 Expression by-Induced Matrix β Amplification of IL-1 (2000) (0)
- Sphingosine kinase 2 induces angiogenic effects by enhancing neovascularisation in the mouse model of retinopathy of prematurity (2016) (0)
- P56. Cytokines and NO upregulate prolyl hydroxylase 3 (PHD-3) mRNA and protein expression in rat renal mesangial cells (2008) (0)
- Contribution of group II phospholipase A2 to arachidonic acid release and prostaglandin synthesis by mesangial cells (1994) (0)
- Overexpression of endothelial cell Cystathionine Gamma Lyase preserves cardiovascular function in heart failure with preserved ejection fraction (2022) (0)
- [intracellular signal transmission]. (1991) (0)
- The E3 Ligase TRIM25 Impairs Apoptotic Cell Death in Colon Carcinoma Cells via Destabilization of Caspase-7 mRNA: A Possible Role of hnRNPH1 (2023) (0)
- Exogenous phospholipases A2 mediate gene expression in rat mesangial cells via PPARalpha activation (2002) (0)
- Transforming growth factor 2 differentially modulates interleukin-ll-and tumour-necrosis-factor-x-stimulated phospholipase A 2 and prostaglandin E 2 synthesis in rat renal mesangial cells (2005) (0)
- Corrigendum to “Identification of the LIM kinase-1 as a ceramide-regulated gene in renal mesangial cells” [Biochem. Biophys. Res. Commun. 298 (2002) 408–413] (2005) (0)
- Differential expression of CD8 defines phenotypically distinct cytotoxic T cells in cancer and multiple sclerosis (2022) (0)
- Erratum: Tristetraprolin regulation of interleukin-22 production (2015) (0)
- NOVEL OXAZOLO-OXAZOLE DERIVATIVES OF FINGOLIMOD INDUCE LYMPHOPENIA AND REDUCE SYMPTOMS OF EAE IN MICE (2018) (0)
- Regulation of Ciap1 and Xiap Expression by Nitric Oxide, Cytokines, and Its Relation to Apotosis Induction in Rat Mesangial Cells and Raw 264.7 Macrophages (2001) (0)
- Platelet-derived growth factor and fibroblast growth factor differentially regulate interleukin 1beta- and cAMP-induced group II phospholipase A2 expression in rat renal mesangial cells. (1998) (0)
- PKC-mediated Regulation of GTP Cyclohydrolase I in Mast Cells and Renal Mesangial Cells (2002) (0)
- Enhanced expression of carnitine palmitoyl transferase-Ia in rat mesangial cells by exogenous secreted phospholipaseA2-IIA (2004) (0)
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