Joseph E. Parrillo
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Philosophy
Joseph E. Parrillo's Degrees
- Doctorate Medicine University of Pennsylvania
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(Suggest an Edit or Addition)Joseph E. Parrillo's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock* (2006) (5090)
- Pathogenetic mechanisms of septic shock. (1993) (1622)
- Profound but reversible myocardial depression in patients with septic shock. (1984) (1334)
- Septic shock in humans. Advances in the understanding of pathogenesis, cardiovascular dysfunction, and therapy. (1990) (1200)
- The cardiovascular response of normal humans to the administration of endotoxin. (1989) (1098)
- Association between arterial hyperoxia following resuscitation from cardiac arrest and in-hospital mortality. (2010) (768)
- Pulmonary artery occlusion pressure and central venous pressure fail to predict ventricular filling volume, cardiac performance, or the response to volume infusion in normal subjects (2004) (756)
- A circulating myocardial depressant substance in humans with septic shock. Septic shock patients with a reduced ejection fraction have a circulating factor that depresses in vitro myocardial cell performance. (1985) (624)
- Early microcirculatory perfusion derangements in patients with severe sepsis and septic shock: relationship to hemodynamics, oxygen transport, and survival. (2007) (592)
- Endotoxin and tumor necrosis factor challenges in dogs simulate the cardiovascular profile of human septic shock (1989) (584)
- Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum. (1996) (572)
- Serial cardiovascular variables in survivors and nonsurvivors of human septic shock: heart rate as an early predictor of prognosis. (1987) (506)
- Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. (2009) (503)
- Promotion and subsequent inhibition of plasminogen activation after administration of intravenous endotoxin to normal subjects. (1989) (494)
- The coronary circulation in human septic shock. (1986) (453)
- Clinical review: Myocardial depression in sepsis and septic shock (2002) (423)
- Verapamil and adriamycin in the treatment of drug-resistant ovarian cancer patients. (1987) (411)
- Early increases in microcirculatory perfusion during protocol-directed resuscitation are associated with reduced multi-organ failure at 24 h in patients with sepsis (2008) (399)
- Mechanisms of glucocorticoid action on immune processes. (1979) (398)
- MULTICENTER STUDY OF EARLY LACTATE CLEARANCE AS A DETERMINANT OF SURVIVAL IN PATIENTS WITH PRESUMED SEPSIS (2008) (380)
- Right ventricular dysfunction and dilatation, similar to left ventricular changes, characterize the cardiac depression of septic shock in humans. (1990) (369)
- Acute kidney injury in septic shock: clinical outcomes and impact of duration of hypotension prior to initiation of antimicrobial therapy (2009) (366)
- Serum lactate as a predictor of mortality in patients with infection (2007) (341)
- Early combination antibiotic therapy yields improved survival compared with monotherapy in septic shock: A propensity-matched analysis* (2010) (333)
- A prospective, randomized, controlled trial of prednisone for dilated cardiomyopathy. (1989) (332)
- Takayasu's arteritis and its therapy. (1985) (326)
- Diagnosis of Pneumocystis carinii pneumonia: improved detection in sputum with use of monoclonal antibodies. (1988) (318)
- Adult respiratory distress syndrome in patients with severe neutropenia. (1986) (311)
- Relationship Between Supranormal Oxygen Tension and Outcome After Resuscitation From Cardiac Arrest (2011) (294)
- The cardiovascular manifestations of the hypereosinophilic syndrome. Prospective study of 26 patients, with review of the literature. (1979) (294)
- Depressed left ventricular performance. Response to volume infusion in patients with sepsis and septic shock. (1988) (289)
- Pulmonary Artery Catheter Consensus conference: consensus statement. (1997) (284)
- Gram-negative bacteremia produces both severe systolic and diastolic cardiac dysfunction in a canine model that simulates human septic shock. (1986) (263)
- Vasopressor and inotropic support in septic shock: An evidence-based review (2004) (257)
- Therapy of the hypereosinophilic syndrome. (1978) (252)
- Translating research to clinical practice: a 1-year experience with implementing early goal-directed therapy for septic shock in the emergency department. (2006) (250)
- Septic shock. Hemodynamics and pathogenesis. (1983) (245)
- A Randomized, Double-Blind, Placebo-Controlled, Phase 2b Study to Evaluate the Safety and Efficacy of Recombinant Human Soluble Thrombomodulin, ART-123, in Patients With Sepsis and Suspected Disseminated Intravascular Coagulation* (2013) (244)
- Cardiorespiratory effects of immunotherapy with interleukin-2. (1989) (240)
- Myocardial dysfunction in the patient with sepsis (2002) (233)
- Prevalent myocarditis at necropsy in the acquired immunodeficiency syndrome. (1988) (227)
- Evolution of critical care cardiology: transformation of the cardiovascular intensive care unit and the emerging need for new medical staffing and training models: a scientific statement from the American Heart Association. (2012) (219)
- Coronary Endothelial Dysfunction After Heart Transplantation Predicts Allograft Vasculopathy and Cardiac Death (2002) (213)
- Role of endotoxemia in cardiovascular dysfunction and mortality. Escherichia coli and Staphylococcus aureus challenges in a canine model of human septic shock. (1989) (209)
- Resuscitating the microcirculation in sepsis: the central role of nitric oxide, emerging concepts for novel therapies, and challenges for clinical trials. (2008) (206)
- Significance of arterial hypotension after resuscitation from cardiac arrest* (2009) (200)
- The duration of hypotension before the initiation of antibiotic treatment is a critical determinant of survival in a murine model of Escherichia coli septic shock: association with serum lactate and inflammatory cytokine levels. (2006) (199)
- Tumor necrosis factor alpha and interleukin 1beta are responsible for in vitro myocardial cell depression induced by human septic shock serum (1996) (192)
- Role of nitric oxide and cGMP in human septic serum-induced depression of cardiac myocyte contractility. (1999) (189)
- Interleukin-2 administration causes reversible hemodynamic changes and left ventricular dysfunction similar to those seen in septic shock. (1988) (181)
- Effect of a Recombinant Human Soluble Thrombomodulin on Mortality in Patients With Sepsis-Associated Coagulopathy: The SCARLET Randomized Clinical Trial. (2019) (177)
- Detection of renal blood flow abnormalities in septic and critically ill patients using a newly designed indwelling thermodilution renal vein catheter. (1990) (177)
- A circulating myocardial depressant substance is associated with cardiac dysfunction and peripheral hypoperfusion (lactic acidemia) in patients with septic shock. (1989) (176)
- Increased microvascular reactivity and improved mortality in septic mice lacking inducible nitric oxide synthase. (2000) (173)
- Risk stratification in unstable angina. Prospective validation of the Braunwald classification. (1995) (168)
- Myocardial dysfunction in septic shock. (2000) (164)
- Clinical characteristics, sepsis interventions and outcomes in the obese patients with septic shock: an international multicenter cohort study (2013) (164)
- Critical care medicine. (1996) (164)
- Bacteremia due to Mycobacterium avium-intracellulare in the acquired immunodeficiency syndrome. (1983) (161)
- The results of transvenous endomyocardial biopsy can frequently be used to diagnose myocardial diseases in patients with idiopathic heart failure. Endomyocardial biopsies in 100 consecutive patients revealed a substantial incidence of myocarditis. (1984) (159)
- Nonspecific interstitial pneumonitis: a common cause of pulmonary disease in the acquired immunodeficiency syndrome. (1987) (156)
- Dermatologic manifestations of the hypereosinophilic syndrome. (1978) (153)
- Norepinephrine alone versus norepinephrine plus low-dose dopamine: enhanced renal blood flow with combination pressor therapy. (1985) (153)
- Sepsis and septic shock: a history. (2009) (148)
- Prognostic factors and life expectancy of patients with acquired immunodeficiency syndrome and Pneumocystis carinii pneumonia. (1987) (148)
- Comparison of the Effector Cells in Human Spontaneous Cellular Cytotoxicity and Antibody‐Dependent Cellular Cytotoxicity: Differential Sensitivity of Effector Cells to in Vivo and in Vitro Corticosteroids (1978) (148)
- Utility of history, physical examination, electrocardiogram, and chest radiograph for differentiating normal from decreased systolic function in patients with heart failure. (2002) (144)
- Purification, toxicity, and antiendotoxin activity of polymyxin B nonapeptide (1989) (144)
- Multiple Organ Dysfunction After Return of Spontaneous Circulation in Postcardiac Arrest Syndrome (2013) (143)
- Responses of left ventricular function in survivors and nonsurvivors of septic shock (1989) (140)
- Nitric oxide synthase inhibition reverses arteriolar hyporesponsiveness to endothelin-1 in septic rats. (1993) (134)
- Identification of antigens and antibodies specific for Pneumocystis carinii. (1988) (130)
- Kaposi's sarcoma causing pulmonary infiltrates and respiratory failure in the acquired immunodeficiency syndrome. (1985) (130)
- Critical Care Medicine: Principles of Diagnosis and Management in the Adult (2001) (129)
- Bacterial lipopolysaccharides prime human neutrophils for enhanced production of leukotriene B4. (1989) (128)
- Tumor necrosis factor challenges in canines: patterns of cardiovascular dysfunction. (1992) (124)
- Timing of vasopressor initiation and mortality in septic shock: a cohort study (2014) (124)
- Early arterial hypotension is common in the post-cardiac arrest syndrome and associated with increased in-hospital mortality. (2008) (121)
- Activation of the kallikrein-kinin system after endotoxin administration to normal human volunteers. (1993) (121)
- Antimicrobial therapeutic determinants of outcomes from septic shock among patients with cirrhosis (2012) (119)
- Interaction Between Fluids and Vasoactive Agents on Mortality in Septic Shock: A Multicenter, Observational Study* (2014) (117)
- The diagnosis of Pneumocystis carinii pneumonia in patients with the acquired immunodeficiency syndrome using subsegmental bronchoalveolar lavage. (1984) (116)
- Dynamic limitation of coronary vasodilator reserve in patients with dilated cardiomyopathy and chest pain. (1987) (116)
- Monoclonal antibodies to Pneumocystis carinii: identification of specific antigens and characterization of antigenic differences between rat and human isolates. (1989) (114)
- Eosinophilic myocarditis. (2005) (110)
- Frequency of myocarditis, left ventricular dysfunction and ventricular tachycardia in the acquired immune deficiency syndrome. (1988) (110)
- Characterization of a hyperdynamic murine model of resuscitated sepsis using echocardiography. (2001) (108)
- Myocardial dysfunction in septic shock: Part II. Role of cytokines and nitric oxide. (2001) (106)
- Myocardial dysfunction in septic shock: Part I. Clinical manifestation of cardiovascular dysfunction. (2001) (104)
- Protective effect of a novel, potent inhibitor of poly(adenosine 5′-diphosphate-ribose) synthetase in a porcine model of severe bacterial sepsis* (2002) (104)
- Improved Early Detection of Sepsis in the ED With a Novel Monocyte Distribution Width Biomarker (2017) (104)
- Myocardial dysfunction in sepsis. (1989) (101)
- Cardiac involvement by Kaposi's sarcoma in acquired immune deficiency syndrome (AIDS). (1984) (100)
- Death in the AIDS patient: role of cytomegalovirus. (1983) (98)
- Nonspecific interstitial pneumonitis without evidence of Pneumocystis carinii in asymptomatic patients infected with human immunodeficiency virus (HIV). (1988) (97)
- The cardiovascular pathophysiology of sepsis. (1989) (96)
- PROSPECTIVE EVALUATION OF A MONOCLONAL ANTIBODY IN DIAGNOSIS OF PNEUMOCYSTIS CARINII PNEUMONIA (1986) (92)
- Dynamic Visualization of Lung Sounds with a Vibration Response Device: A Case Series (2007) (92)
- Malate-aspartate shuttle, cytoplasmic NADH redox potential, and energetics in vascular smooth muscle. (1998) (91)
- Unstable angina and non-Q wave myocardial infarction: does the clinical diagnosis have therapeutic implications? (1999) (90)
- Clinical characteristics and outcomes of septic patients with new-onset atrial fibrillation. (2008) (89)
- Cardiovascular performance with E. coli challenges in a canine model of human sepsis. (1988) (89)
- Characterization of de novo folate synthesis in Pneumocystis carinii and Toxoplasma gondii: potential for screening therapeutic agents. (1989) (88)
- Human eosinophils. Purification and cytotoxic capability of eosinophils from patients with the hypereosinophilic syndrome. (1978) (87)
- Echocardiography for hemodynamic assessment of patients with advanced heart failure and potential heart transplant recipients. (1997) (86)
- Value of the American College of Cardiology/American Heart Association stenosis morphology classification for coronary interventions in the late 1990s. (1998) (83)
- A lipid A analog, E5531, blocks the endotoxin response in human volunteers with experimental endotoxemia (2000) (82)
- Perceptions of a critically ill patient experiencing therapeutic paralysis in an ICU (1984) (79)
- Monocyte Distribution Width: A Novel Indicator of Sepsis-2 and Sepsis-3 in High-Risk Emergency Department Patients* (2019) (79)
- Disseminated Mycobacterium haemophilum infection in two patients with the acquired immunodeficiency syndrome. (1988) (77)
- Potent antipneumocystis and antitoxoplasma activities of piritrexim, a lipid-soluble antifolate (1988) (77)
- Regional distribution of acoustic-based lung vibration as a function of mechanical ventilation mode (2007) (76)
- Endocarditis due to resistant viridans streptococci during oral penicillin chemoprophylaxis. (1979) (72)
- Detection of Pneumocystis carinii by fluorescent-antibody stain using a combination of three monoclonal antibodies (1987) (72)
- From the bench to the bedside: the future of sepsis research. Executive summary of an American College of Chest Physicians, National Institute of Allergy and Infectious Disease, and National Heart, Lung, and Blood Institute Workshop. (1997) (72)
- Admission of AIDS patients to a medical intensive care unit: causes and outcome. (1989) (71)
- Heart disease and the eosinophil. (1990) (71)
- Human Serum from Patients with Septic Shock Activates Transcription Factors STAT1, IRF1, and NF-κB and Induces Apoptosis in Human Cardiac Myocytes* (2005) (69)
- Cardiovascular response to dobutamine stress predicts outcome in severe sepsis and septic shock (2008) (69)
- Changes in coronary endothelial function predict progression of allograft vasculopathy after heart transplantation. (2004) (69)
- Point-of-care assessment of microvascular blood flow in critically ill patients (2009) (67)
- Cardiovascular dysfunction in septic shock. (1991) (67)
- Inhibition of endotoxin-induced priming of human neutrophils by lipid X and 3-Aza-lipid X. (1987) (67)
- The use of APACHE II scores to select candidates for left ventricular assist device placement. Acute Physiology and Chronic Health Evaluation. (1998) (66)
- Myocardial dysfunction in sepsis. Recent insights. (1989) (65)
- Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study. (2007) (65)
- Inflammatory cardiomyopathy (myocarditis): which patients should be treated with anti-inflammatory therapy? (2001) (65)
- Adult Respiratory Distress Syndrome in Patients with Severe Neutropenia (1987) (65)
- Pulmonary and oxygen transport effects of intravenously administered endotoxin in normal humans. (1992) (64)
- Electrocardiographic diagnosis of acute myocardial infarction: Current concepts for the clinician. (2001) (64)
- Fluid resuscitation influences cardiovascular performance and mortality in a murine model of sepsis (2009) (63)
- The effect of tumor necrosis factor on vascular smooth muscle. In vitro studies using rat aortic rings. (1991) (63)
- Norepinephrine alone versus norepinephrine plus low‐dose dopamine: Enhanced renal blood flow with combination pressor therapy (1985) (63)
- Morphological and quantitative angiographic analyses of progression of coronary stenoses. A comparison of Q-wave and non-Q-wave myocardial infarction. (1994) (62)
- Critical care in the United States. Who are we and how did we get here? (1997) (61)
- Cardiogenic Shock (1999) (61)
- Septic shock--vasopressin, norepinephrine, and urgency. (2008) (61)
- Cloning and Characterization of the Human Heparanase-1 (HPR1) Gene Promoter (2002) (60)
- Impaired microvascular vasoconstrictive responses to vasopressin in septic rats. (1997) (59)
- Activation of phosphatidylinositol turnover in rat aorta by α1-adrenergic receptor stimulation (1985) (59)
- Pseudomonas aeruginosa compared with Escherichia coli produces less endotoxemia but more cardiovascular dysfunction and mortality in a canine model of septic shock. (1990) (58)
- The pathophysiology of septic shock. (2009) (58)
- Nitric oxide-dependent and -independent mechanisms are involved in TNF-alpha -induced depression of cardiac myocyte contractility. (2007) (57)
- Critical Care Medicine: Principles of Diagnosis and Management (1995) (54)
- Preload-independent mechanisms contribute to increased stroke volume following large volume saline infusion in normal volunteers: a prospective interventional study (2004) (53)
- Transcriptional Regulation of Fas Gene Expression by GA-binding Protein and AP-1 in T Cell Antigen Receptor·CD3 Complex-stimulated T Cells* (1999) (53)
- Adenosine deaminase inhibition attenuates microvascular dysfunction and improves survival in sepsis. (2002) (51)
- RANDOMIZED, BLINDED, PLACEBO‐CONTROLLED TRIAL OF TISSUE FACTOR PATHWAY INHIBITOR IN PORCINE SEPTIC SHOCK (1998) (50)
- Culture-Negative Septic Shock Compared With Culture-Positive Septic Shock: A Retrospective Cohort Study (2018) (50)
- Chronic granulomatous disease. Diagnosis in a 27-year-old man with Mycobacterium fortuitum. (1975) (50)
- Mechanisms of corticosteroid action on lymphocyte subpopulations. III. Differential effects of dexamethasone administration on subpopulations of effector cells mediating cellular cytotoxicity in man. (1978) (49)
- Plasma exchange does not improve survival in a canine model of human septic shock (1993) (49)
- Does low individual operator coronary interventional procedural volume correlate with worse institutional procedural outcome? (1997) (49)
- Use of a standardized order set for achieving target temperature in the implementation of therapeutic hypothermia after cardiac arrest: a feasibility study. (2008) (48)
- Reduction in Reperfusion‐Induced Myocardial Necrosis in Dogs by RheothRx Injection (Poloxamer 188 N.F.), a Hemorheological Agent That Alters Neutrophil Function (1994) (48)
- Organization and staffing practices in US cardiac intensive care units: a survey on behalf of the American Heart Association Writing Group on the Evolution of Critical Care Cardiology (2013) (48)
- Inclusion criteria for clinical trials in sepsis: did the American College of Chest Physicians/Society of Critical Care Medicine consensus conference definitions of sepsis have an impact? (2005) (47)
- Cardiogenic shock. (1999) (46)
- Evidence of transcellular permeability pathway in microvessels. (2001) (46)
- Mediator modulation therapy of severe sepsis and septic shock: does it work? (2004) (46)
- Potent effect of trimetrexate, a lipid-soluble antifolate, on Toxoplasma gondii. (1987) (46)
- Mycobacterium tuberculosis septic shock. (2013) (46)
- Nitric oxide synthase inhibition increases venular leukocyte rolling and adhesion in septic rats (2000) (45)
- Monocyte distribution width enhances early sepsis detection in the emergency department beyond SIRS and qSOFA (2020) (45)
- Septic shock in humans (2020) (45)
- Immunologic reactivity in the hypereosinophilic syndrome. (1979) (45)
- Effect of 100% oxygen administration on infarct size and left ventricular function in a canine model of myocardial infarction and reperfusion. (1995) (45)
- Protein-free phospholipid emulsion treatment improved cardiopulmonary function and survival in porcine sepsis. (2003) (45)
- Induced sputum to diagnose Pneumocystis carinii pneumonia in immunosuppressed pediatric patients. (1989) (44)
- Role of nitric oxide and cGMP in human septic serum-induced depression of cardiac myocyte contractility. (1999) (44)
- Utilization of coronary angiography and revascularization after acute myocardial infarction in men and women risk stratified by the American College of Cardiology/American Heart Association guidelines. (2000) (44)
- Effect of large volume infusion on left ventricular volumes, performance and contractility parameters in normal volunteers (2004) (44)
- Neutralization of endotoxin by a phospholipid emulsion in healthy volunteers. (2005) (43)
- Discordance between microcirculatory alterations and arterial pressure in patients with hemodynamic instability. (2012) (43)
- Randomized Controlled Trial of Inhaled Nitric Oxide for the Treatment of Microcirculatory Dysfunction in Patients With Sepsis* (2014) (43)
- Management of septic shock: present and future. (1991) (43)
- Peak systolic pressure/end‐systolic volume ratio, a load‐independent measure of ventricular function, is reversibly decreased in human septic shock (1994) (42)
- Hypertension and Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19 (2020) (42)
- Clinical practice guidelines in unstable angina improve clinical outcomes by assuring early intensive medical treatment. (1999) (41)
- A PORCINE MODEL OF PERITONITIS AND BACTEREMIA SIMULATES HUMAN SEPTIC SHOCK (1996) (40)
- The management of pneumonias in immunocompromised patients. (1985) (40)
- Indolent epidemic of Pseudomonas cepacia bacteremia and pseudobacteremia in an intensive care unit traced to a contaminated blood gas analyzer. (1988) (39)
- PORCINE MODELS OF SEVERE SEPSIS: EMPHASIS ON PORCINE PERITONITIS (2005) (39)
- Major issues in critical care medicine (1984) (38)
- Discordance between microvascular permeability and leukocyte dynamics in septic inducible nitric oxide synthase deficient mice (2007) (38)
- Effects of nitric oxide synthase inhibition on microvascular reactivity in septic mice. (1999) (38)
- Severe sepsis and therapy with activated protein C. (2005) (37)
- Interleukin-10 blunts the human inflammatory response to lipopolysaccharide without affecting the cardiovascular response (2005) (36)
- Echocardiography and nuclear cardiac imaging in the critical care unit. (1985) (36)
- Endotoxin administration to humans primes alveolar macrophages for increased production of inflammatory mediators (1994) (35)
- Necrotizing vasculitis, coronary angiitis, and the cardiologist. (1980) (34)
- Involvement of Rho kinase (ROCK) in sepsis-induced acute lung injury. (2012) (34)
- Genetic factors in septic shock. (1999) (34)
- Assessing coronary blood flow dynamics with the TIMI frame count method: Comparison with simultaneous intracoronary Doppler and ultrasound (2001) (34)
- Experimental human endotoxemia is associated with depression of load-independent contractility indices: prevention by the lipid a analogue E5531. (2004) (33)
- Ventricular dilation is associated with improved cardiovascular performance and survival in sepsis. (2010) (33)
- Erysipelothrix rhusiopathiae bacteremia presenting as septic shock. (1985) (32)
- Hemodynamic effects of dopamine, norepinephrine, and fluids in a dog model of sepsis. (1995) (31)
- Cloning and Characterization of the Human Heparanase-1 (HPR1) Gene Promoter ROLE OF GA-BINDING PROTEIN AND Sp1 IN REGULATING HPR1 BASAL PROMOTER ACTIVITY* (2002) (31)
- Prospective Evaluation of Autonomic Dysfunction in Post-Acute Sequela of COVID-19 (2022) (31)
- Effectiveness of chart prompts to improve physician compliance with the National Cholesterol Education Program guidelines. (2001) (30)
- Neutrophil aggregating activity and septic shock in humans: Neutrophil aggregation by a C5a-like material occurs more frequently than complement component depletion and correlates with depression of systemic vascular resistance (1988) (29)
- Therapeutic trial of lipid X in a canine model of septic shock. (1993) (28)
- Cytoplasmic redox potential affects energetics and contractile reactivity of vascular smooth muscle. (1997) (28)
- Simultaneous intracoronary ultrasound and Doppler flow studies distinguish flow‐mediated from receptor‐mediated endothelial responses (1999) (28)
- Chapter 22 – Shock: Classification, Pathophysiology, and Approach to Management (2008) (28)
- Cardiogenic shock. (2008) (28)
- Hypotension, acidosis, and vasodilatation syndrome post-heart transplant: prognostic variables and outcomes. (2001) (28)
- Transforming growth factor-beta1 blocks in vitro cardiac myocyte depression induced by tumor necrosis factor-alpha, interleukin-1beta, and human septic shock serum. (2007) (28)
- Direct current cardioversion: indications, techniques, and recent advances. (2000) (27)
- Transforming growth factor-&bgr;1 blocks in vitro cardiac myocyte depression induced by tumor necrosis factor-&agr;, interleukin-1&bgr;, and human septic shock serum (2007) (27)
- Metabolic fate of glucose in vascular smooth muscle during contraction induced by norepinephrine. (1998) (27)
- Effects of epinephrine and amrinone on contractility and cyclic adenosine monophosphate generation of tumor necrosis factor alpha-exposed cardiac myocytes. (1999) (27)
- Fatty acid, tricarboxylic acid cycle metabolites, and energy metabolism in vascular smooth muscle. (1994) (26)
- NADH/NAD redox state of cytoplasmic glycolytic compartments in vascular smooth muscle. (2000) (26)
- Renal hemodynamics and prostaglandin E2 excretion in a nonhuman primate model of septic shock (1990) (26)
- Discordant epicardial and microvascular endothelial responses in heart transplant recipients early after transplantation. (1998) (26)
- Therapeutic hypothermia and vasopressor dependency after cardiac arrest. (2013) (26)
- How well does radionuclide dipyridamole stress testing detect three-vessel coronary artery disease and ischemia in the region supplied by the most stenotic vessel? (1999) (25)
- Transfusion of packed red blood cells is not associated with improved central venous oxygen saturation or organ function in patients with septic shock. (2012) (25)
- Cardiac endothelin release and infarct size, myocardial blood flow, and ventricular function in canine infarction and reperfusion. (1996) (25)
- Effect of septic serum on vascular smooth muscle: In vitro studies using rat aortic rings (1992) (24)
- Clinical predictors easily obtained at presentation predict resource utilization in unstable angina. (1998) (24)
- Production of lactic acid and energy metabolism in vascular smooth muscle: effect of dichloroacetate. (1995) (24)
- Cardiovascular dysfunction in sepsis and septic shock (2000) (24)
- Incidence and Outcomes Associated With Early Heart Failure Pharmacotherapy in Patients With Ongoing Cardiogenic Shock (2014) (24)
- Quantitative analysis of polymorphonuclear leukocyte superoxide anion generation in critically ill children (1985) (23)
- Intubation of the trachea in the critical care setting. (1985) (23)
- Location of patients before transfer to a tertiary care intensive care unit: impact on outcome. (2009) (23)
- Closed loop television tracking of beating heart cells in vitro. (1987) (23)
- Validated risk stratification model accurately predicts low risk in patients with unstable angina. (1998) (23)
- BACTERIAL DNA AND RNA INDUCE RAT CARDIAC MYOCYTE CONTRACTION DEPRESSION IN VITRO (2004) (23)
- Unresponsiveness of Legionella bozemanii pneumonia to erythromycin administration despite in vitro sensitivity. (1983) (21)
- Differential effects of fatty acids on glycolysis and glycogen metabolism in vascular smooth muscle. (1991) (21)
- The impact of packed red blood cell transfusion on clinical outcomes in patients with septic shock treated with early goal directed therapy (2010) (21)
- Inhibition of lymphocyte transformation by a placental glycoprotein. (1971) (21)
- Septic shock: the cardiovascular abnormality and therapy. (1989) (20)
- Cardiac dysfunction during septic shock. (1996) (20)
- Cardiovascular effects and safety of intravenous and intramuscular pentamidine isethionate. (1987) (20)
- Immediate and 1‐Year Survival of Out‐of‐Hospital Cardiac Arrest Victims in Southern New Jersey: (2004) (20)
- Association between out-of-hospital emergency department transfer and poor hospital outcome in critically ill stroke patients. (2011) (20)
- Agranulocytosis following infectious mononucleosis. (1973) (20)
- Outcome measures utilized in clinical trials of interventions for post-cardiac arrest syndrome: a systematic review. (2009) (20)
- Characterization of the direct effects of cyclophosphamide on cell-mediated immunological responses. (1977) (20)
- Critical care medicine as a distinct product line with substantial financial profitability: The role of business planning (2004) (20)
- Efficacy of trimetrexate, a potent lipid-soluble antifolate, in the treatment of rodent Pneumocystis carinii pneumonia. (1988) (19)
- Improved risk stratification in unstable angina: Identification of patients at low risk for in‐hospital cardiac events by admission echocardiography (1998) (19)
- Cost and appropriateness of radionuclide exercise stress testing by cardiologists and non-cardiologists. (1996) (19)
- The hypereosinophilic syndrome: dramatic response to therapeutic intervention. (1977) (19)
- Reversible causes of severe myocardial dysfunction. (1997) (19)
- Angiotensin converting enzyme inhibitors in bone marrow transplant recipients with depressed left ventricular function. (1995) (18)
- Cofactors V and VIII after endotoxin administration to human volunteers. (1995) (17)
- Apparent direct cellular cytotoxicity mediated via cytophilic antibody. Multiple Fc receptor bearing effector cell populations mediating cytophilic antibody induced cytotoxicity. (1977) (17)
- Electrocardiographic abnormalities in mitral valve prolapse. (1992) (17)
- Cardiac Disease in Myasthenia Gravis: A Literature Review (2003) (17)
- A prospective multicenter cohort study of the association between global tissue hypoxia and coagulation abnormalities during early sepsis resuscitation (2010) (16)
- 3,5,3'-Triiodo-L-thyronine induces cardiac myocyte differentiation but not neuronal differentiation in P19 teratocarcinoma cells in a dose dependent manner. (1994) (16)
- Serum neopterin levels following intravenous endotoxin administration to normal humans. (1990) (16)
- Emergency department inter-hospital transfer for post-cardiac arrest care: initial experience with implementation of a regional cardiac resuscitation center in the United States. (2013) (16)
- Blood histamine concentrations are not elevated in humans with septic shock. (1989) (16)
- Continuous cardiac index monitoring: A prospective observational study of agreement between a pulmonary artery catheter and a calibrated minimally invasive technique. (2009) (16)
- Substrate-dependent alteration in O2 consumption and energy metabolism in vascular smooth muscle. (1996) (15)
- The pathophysiology of septic shock. (2011) (14)
- Circulating substances and energy metabolism in septic shock. (2003) (13)
- Economics of critical care: Medicare part A versus part B payments (2006) (13)
- Frequency of abrupt vessel closure and side branch occlusion after percutaneous coronary intervention in a 6.5-year period (1994 to 2000) at a single medical center. (2002) (13)
- Prevalence of angiographically significant stenosis in patients with chest pain and an elevated troponin I level and normal creatine kinase and creatine kinase-MB levels. (2001) (13)
- Bioavailability of oral trimetrexate in patients with acquired immunodeficiency syndrome (1988) (13)
- A silver anniversary for the Society of Critical Care Medicine--visions of the past and future: the presidential address from the 24th Educational and Scientific Symposium of the Society of Critical Care Medicine. (1995) (13)
- Comparison of heparin therapy for < or = 48 hours to > 48 hours in unstable angina pectoris. (1997) (13)
- Examination of the enzyme assay for NADPH oxidoreductase; application to polymorphonuclear leukocyte superoxide anion generation. (1985) (13)
- Prognostic factors in sepsis: The cold facts (1992) (13)
- Accurate noninvasive estimation of left ventricular end-diastolic pressure: comparison with catheterization. (1998) (13)
- Severe Pneumocystis carinii pneumonia produces a hyperdynamic profile similar to bacterial pneumonia with sepsis (1994) (13)
- Assessment of Asymmetric Lung Disease in Intensive Care Unit Patients Using Vibration Response Imaging (2008) (13)
- The Cardiovascular Patho Physiology Of Sepsis (1989) (13)
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- Release of soluble myocardial depressant activity by reperfused myocardium (1996) (3)
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- INCREASED SPATIAL DISTRIBUTION OF AIRFLOW IN LUNGS WITH LOW-LEVEL PRESSURE SUPPORT VENTILATION VS MAINTENANCE-ASSIST VOLUME CONTROL (2006) (2)
- 744-6 Impaired Arteriolar Responsiveness to Endothelin-1 in Septic Rats is Reversed by NG-Methyl-L-Arginine (1995) (2)
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- Chapter 24 – Septic Shock (2008) (1)
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- IMPACT OF BLOOD TRANSFUSION ON NOSOCOMIAL INFECTIONS IN CRITICALLY ILL PATIENTS (2007) (1)
- THE NATIONAL HISTORY OF IDIOPATHIC DILATED CARDIOMYOPATHY: PROSPECTIVE SURVIVAL AND THE IMPACT OF TRANSPLANATION (1988) (1)
- CARDIAC EFFECTS OF SUPRAPHARMACOLOGIC DOSES OF VERAPAMIL (1986) (1)
- Chapter 26 – Severe Sepsis and Multiple Organ Dysfunction (2008) (1)
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- Severe Heart Failure in the ICU (2005) (1)
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- CHANGES IN LEFT VENTRICULAR FUNCTION IN HUMANS WITH SEPTIC SHOCK (1986) (1)
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- EFFECT OF SEPTIC SHOCK ON CARDIOVASCULAR RESPONSES TO DOPAMINE (DA) AND NOREPINE PHRINE (NE) IN A CONSCIOUS CANINE MODEL (1993) (1)
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- EMERGENCY OPEN LUNG BIOPSY AT NIH: USE OF A NEW MODIFIED METHYLENE BLUE STAIN FOR THE RAPID TISSUE DEMONSTRATION OF LEGIONELLA, PNEUMOCYSTIS, CYTOMEGALOVIRUS, NOCARDIA AND FUNGI CAUSING OPPORTUNISTIC PNEUMONIAS (1983) (1)
- MICROCIRCULATORY PERFUSION IN SEVERE SEPSIS CORRELATES WITH HEMODYNAMIC PARAMETERS: 558 (2004) (1)
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- THE CARDIOVASCULAR RESPONSE TO VOLUME LOADING DURING INHALATIONAL ANESTHESIA (1989) (1)
- In Memoriam: Roger C. Bone, MD, PhD(Hon), MACP, MFCCP, FCCM (1997) (1)
- Cardiovascular dysfunction in human septic shock. (1989) (1)
- 221 Dose-response Of E5531, A Lipid A Antagonist, In The Suppression Of Response To Endotoxin In Normal Volunteers (1995) (1)
- Chronic Models of Endotoxemia and Sepsis: Lessons from Both a Canine Peritonitis and a Human Endotoxemia Model (1993) (1)
- The role of endotoxin in human septic shock: therapeutic potential of lipid A analogs. (1989) (1)
- INTERLEUKIN‐1 &bgr;‐INDUCED MYOCARDIAL CELL DEPRESSION IS MEDIATED BY NITRIC OXIDE AND CYCLIC GMP GENERATION. (1995) (1)
- Admission echocardiography predicts in-hospital cardiac events in patients with unstable angina (1996) (1)
- IL-1β BUT NOT ENDOTOXIN, IL-2, IL-4, IL-6, IL-8, IL-10, OR INTERFERON-γ DEPRESSES MYOCARDIAL CELL CONTRACTILITY IN VITRO. (1995) (1)
- Platelet activating factor is an important mediator of myocardial reperfusion injury (1991) (1)
- The effects of heterologous platelet transfusion on pulmonary function during ARDS. (1990) (1)
- OBJECTIVE PROGNOSTIC FACTORS FOR PATIENTS WITH PNEUMOCYSTIS CARINII PNEUMONIA AND THE ACQUIRED IMMUNODEFICIENCY SYNDROME (1987) (1)
- DURATION OF HYPOTENSION PRIOR TO ANTIBIOTIC THERAPY IS A CRITICAL DETERMINANT OF SURVIVAL IN A MURINE MODEL OF E. COLI SEPTIC SHOCK: 507 (2004) (1)
- Targeting host E-selectin expression by antisense oligodeoxynucleotides as potential antiendotoxin therapy in vivo. (2010) (1)
- Right Ventricular Dysfunction in Critically Ill Patients With COVID-19 (2022) (1)
- Gated SPECT with Emory, Cedar-Sinai (Odyssei) and Yale (Wackers) software comparing to 2D echocardiography for evaluation of ejection fraction (2004) (1)
- THE EFFECT OF MECHANICAL VENTILATION MODES ON LUNG VIBRATION ENERGY (2006) (1)
- Critical care medicine. (1992) (1)
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- Moving some articles to electronic (online) only publication. (2013) (1)
- Altered Cardiac Gene Expression During E. coli Porcine Peritonitis (2007) (0)
- SELECTIVE IMMUNOABSORPTION OF IL-1 AND TNF ABROGATES THE IN-VITRO CARDIOMYOCYTE DEPRESSANT EFFECT OF HUMAN SEPTIC SERUM (1994) (0)
- LENGTH OF STAY IN COMMUNITY INTENSIVE CARE UNITS PRIOR TO TRANSFER TO A TERTIARY CENTER: IMPACT ON OUTCOME (2008) (0)
- WILL INSTITUTION OF A POLICY REQUIRING ROUTINE PREOPERATIVE PULMONARY FUNCTION TESTS (PFT) IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFTING (CABG) CHANGE THE POST OPERATIVE OUTCOMES?: 9 (2006) (0)
- CARDIOVASCULAR THURSDAY, MAY 28TH, 1987 SOUTH BALLROOM 10: 15–12 (1987) (0)
- Cardiogenic Shock in other Heart Diseases: Acute Decompensation of Chronic Heart Failure, Myocarditis, Transient Apical Ballooning Syndrome, Peripartum Cardiomyopathy, Hypertrophic Cardiomyopathy, Restrictive Cardiomyopathies, and Thyrotoxicosis (2009) (0)
- DIFFERENT MICROORGANISMS PRODUCE SIMILAR HEMODYNAMIC CHANGES, BUT DIFFERENT ENDOTOXIN CONCENTRATIONS, IN A CANINE MODEL OF SEPTIC SHOCK (1986) (0)
- LOSS OF LINEARITY OF THE FRANK-STARLING RELATIONSHIP DURING SEPSIS INDUCED VENTRICULAR DYSFUNCTION (1986) (0)
- IMPAIRMENT OF OKADAIC ACID INDUCED VASOCONSTRICTION IN SEPTIC RATS (1999) (0)
- THE EJECTION FRACTION CORRELATES WITH THE SLOPE OF THE FRANK-STARLING RELATIONSHIP IN A CONSCIOUS DOG MODEL THAT SIMULATES HUMAN SEPTIC SHOCK (1986) (0)
- SELECTIVE NITRIC OXIDE SYNTHASE INHIBITION IMPROVES MICROVASCULAR RESPONSIVENESS TO ENDOTHELIN-1 IN SEPTIC MICE (1999) (0)
- Simultaneous intravascular ultrasound and doppler wire studies demonstrate a dissociation between coronary flow and area responses following heart transplant (1996) (0)
- VIBRATION RESPONSE IMAGING DURING MECHANICAL VENTILATION: EXPLANATION FOR MERGING OF INSPIRATORY AND EXPIRATORY VIBRATION WAVEFORMS (2006) (0)
- ENDOTHELIAL DYSFUNCTION ON SERIAL STUDIES PREDICTS PROGRESSION OF CARDIAC ALLOGRAFT VASCULOPATHY: Research Citation F (2002) (0)
- THE EJECTION FRACTION PREDICTS SURVIVAL IN A CANINE MODEL THAT SIMULATES HUMAN SEPTIC SHOCK (1986) (0)
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- Hypertensive response to exercise: impact on spect radionuclide imaging and angiographic correlation (2004) (0)
- HEMODYNAMIC PROFILES OF SHOCK IN CRITICALLY ILL COVID PATIENTS (2021) (0)
- FLUID LOADING ELIMINATES DIFFERENCES IN CARDIOVASCULAR RESPONSES TO DOPAMINE AND NOREPINEPHRINE IN AWAKE DOGS (1990) (0)
- CRT-807 Prognostic Impact of Improvement in Intra-Operative Pulmonary Artery Systolic Pressure and Left Ventricular Ejection Fraction in Patients Undergoing Trans-Catheter Aortic Valve Replacement (2015) (0)
- GENDER DIFFERENCES IN LONG TERM SURVIVAL AFTER TRANS-CATHETER AORTIC VALVE REPLACEMENT IN PATIENTS WITH SEVERE AORTIC STENOSIS (2015) (0)
- Is our journal, Critical Care Medicine, entering adulthood? Some thoughts of an almost veteran Editor-in-Chief (1999) (0)
- Communications to the EditorA Circulating Myocardial Depressant Substance in Septic Shock (1990) (0)
- Comprar Critical Care Medicine, 4th Edition | Joseph E. Parrillo | 9780323089296 | Mosby (2013) (0)
- Comprar Critical Care Medicine, 4th Edition | Joseph E. Parrillo | 9780323089296 | Mosby (2013) (0)
- THE EFFECTS OF CATECHOLAMINES (CTE) ON CARDIOVASCULAR (CV) FUNCTION IN A CANINE MODEL OF HUMAN SEPTIC SHOCK (SS) (1988) (0)
- Comprar Critical Care Medicine, 4th Edition | Joseph E. Parrillo | 9780323089296 | Mosby (2013) (0)
- REGULATION OF NOREPINEPHRINE-MEDIATED VASCULAR CONTRACTILITY (1985) (0)
- SENSITIVITY OF RELEVANT ICD-9 AND CPT CODES TO RETROSPECTIVELY CAPTURE PATIENTS WITH A PROSPECTIVELY ASCERTAINED STANDARDIZED DIAGNOSIS OF SEVERE SEPSIS.: 109 (2006) (0)
- Abstract 11329: Prospective Analysis of Vascular Resistance in Patients with Persistent Tachycardia and or Dyspnea on Exertion in the Post Acute Sequela of Covid-19 Syndrome (2021) (0)
- Changes in heart rate volatility in a murine model of sepsis (2006) (0)
- compartments in vascular smooth muscle NADH/NAD redox state of cytoplasmic glycolytic (2006) (0)
- SAI-10: New use of contrast-enhanced assessment of carotid wall intimal-medial thickness: initial observations (2001) (0)
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- CORRELATIONS OF CHEST RADIOGRAPHIC FINDINGS WITH VIBRATION RESPONSE IMAGING IN MECHANICALLY VENTILATED PATIENTS.: 12 (2006) (0)
- Abstract 77: Nitric Oxide in Sepsis: Friend or Foe? Hemodynamics in a Murine Model (2006) (0)
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- THE ROLE OF SEQUENTIAL GALLIUM SCANNING IN AIDS PATIENTS DURING TREATMENT FOR PNEUMOCYSTIS CARINII PNEUMONIA (1987) (0)
- ACCP-SEEK board review question of the month. A 64-year-old man enters the ICU with hypotension and pulmonary edema associated with persistent chest pain. Answer: C. Hibernating myocardium. (1999) (0)
- INDUCIBLE NO IN SEPSIS: FRIEND OR FOE? ECHOCARDIOGRAPHIC STUDY IN A MURINE MODEL.: 60 (2005) (0)
- THE ADULT RESPIRATORY DISTRESS SYNDROME: CLINICAL AND PATHOLOGIC EVIDENCE FOR ITS OCCURRENCE IN NEUTROPENIC PATIENTS (1985) (0)
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- Excimer laser ablation before autoperfusion balloon inflation: a novel therapeutic approach to high grade stenoses in vessels supplying substantial myocardium at risk. (1992) (0)
- Acute Heart Failure and Myocarditis (2008) (0)
- Survival in Human Septic Shock Therapy Results in a Fivefold Reduction of Initiation of Inappropriate Antimicrobial (2009) (0)
- CHARACTERIZATION OF THE JAK/STAT PATHWAY DURING SEPSIS (1999) (0)
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- DIFFERENT MICROORGANISMS PRODUCE SIMILAR SEVERE SYSTOLIC MYOCARDIAL DYSFUNCTION IN A CANINE MODEL THAT SIMULATES HUMAN SEPSIS (1986) (0)
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- CAN A NEW LUNG IMAGING MODALITY BE ADDITIONALLY USEFUL WHEN CHEST RADIOGRAPHS ARE NORMAL (2008) (0)
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- The Pathogenesis of Septic Shock-Reply (1984) (0)
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- ANTIBIOTICS AND FLUID RESUSCITATION IN A MURINE MODEL OF SEPTIC SHOCK (1999) (0)
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- ECHOCARDIOGRAPHIC ESTIMATION OF PULMONARY CAPILLARY WEDGE PRESSURE IN CRITICALLY ILL PATIENTS (1987) (0)
- EVALUATION OF PRESENTATION AND OUTCOMES OF SEPTIC SHOCK PATIENTS OVER AN 18-MONTH PERIOD (2008) (0)
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- MYOCARDIAL DEPRESSION MEASURED WITH A MICROCONDUCTANCE CATHETER IN A MURINE MODEL OF ENDOTOXIC SHOCK: 322 (2002) (0)
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- IMPACT OF BODY MASS INDEX ON MORTALITY IN PATIENTS WITH SEPTIC SHOCK.: 214-T (2005) (0)
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- EARLY DEPRESSION OF CARDIAC MYOCYTE CONTRACTILITY INDUCED BY A SYNERGISTIC COMBINATION OF TNF alpha AND IL-1 beta IS MEDIATED BY CONSTITUTIVE NITRIC OXIDE (NO) SYNTHETASE AND CYCLIC GMP (cGMP) (1998) (0)
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