Joseph T. Coyle
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Why Is Joseph T. Coyle Influential?
(Suggest an Edit or Addition)Joseph T. Coyle's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Oxidative stress, glutamate, and neurodegenerative disorders. (1993) (3863)
- Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. (1982) (3549)
- Alzheimer's disease: a disorder of cortical cholinergic innervation. (1983) (2993)
- Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis (1981) (1721)
- Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea (1976) (1149)
- Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia (2008) (964)
- Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress (1989) (940)
- Glutamate and Schizophrenia: Beyond the Dopamine Hypothesis (2006) (911)
- The emerging role of glutamate in the pathophysiology and treatment of schizophrenia. (2001) (896)
- Oxidative stress in neurodegenerative diseases. (1996) (790)
- CATECHOLAMINES IN FETAL AND NEWBORN RAT BRAIN (1973) (788)
- Neurobiology of Schizophrenia (2006) (720)
- Neurochemical aspects of the ontogenesis of gabanergic neurons in the rat brain (1976) (697)
- Abnormal excitatory amino acid metabolism in amyotrophic lateral sclerosis (1990) (646)
- D-serine added to antipsychotics for the treatment of schizophrenia (1998) (644)
- Immunocytochemical localization of N-acetyl-aspartate with monoclonal antibodies (1991) (638)
- Glutamatergic mechanisms in schizophrenia. (2003) (599)
- Nicotinic acetylcholine binding sites in Alzheimer's disease (1986) (486)
- In situ injection of kainic acid: A new method for selectively lesioning neuronal cell bodies while sparing axons of passage (1978) (475)
- Topographic analysis of the innervation of the rat neocortex and hippocampus by the basal forebrain cholinergic system (1983) (473)
- Abnormal excitatory neurotransmitter metabolism in schizophrenic brains. (1995) (469)
- Striatal lesions with kainic acid: neurochemical characteristics (1977) (458)
- Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas. (1969) (455)
- Evidence for a cholinergic projection to neocortex from neurons in basal forebrain. (1979) (452)
- Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake (1990) (439)
- A placebo-controlled trial of D-cycloserine added to conventional neuroleptics in patients with schizophrenia. (1999) (424)
- Modulation of N-methyl-D-aspartate receptor function by glycine transport. (1998) (416)
- N-Acetylaspartate in neuropsychiatric disorders (1995) (411)
- Review of the Toxicology of Chlorpyrifos With an Emphasis on Human Exposure and Neurodevelopment (2008) (408)
- Regional differences in H3-norepinephrine and H3-dopamine uptake into rat brain homogenates. (1969) (407)
- Dopamine receptors localised on cerebral cortical afferents to rat corpus striatum (1978) (394)
- The role of glutamatergic neurotransmission in the pathophysiology of alcoholism. (1998) (387)
- Lesions in nucleus basalis magnocellularis and medial septal area of rats produce qualitatively similar memory impairments (1985) (385)
- N‐Acetyl‐Aspartyl‐Glutamate: Regional Levels in Rat Brain and the Effects of Brain Lesions as Determined by a New HPLC Method (1984) (379)
- Finding the Intracellular Signaling Pathways Affected by Mood Disorder Treatments (2003) (375)
- The glutamatergic basis of human alcoholism. (1995) (372)
- Prostate-specific membrane antigen is a hydrolase with substrate and pharmacologic characteristics of a neuropeptidase. (1996) (346)
- NMDA receptor and schizophrenia: a brief history. (2012) (342)
- Antiparkinsonian Drugs: Inhibition of Dopamine Uptake in the Corpus Striatum as a Possible Mechanism of Action (1969) (329)
- Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. Identification and characterization of a novel N-acetylated alpha-linked acidic dipeptidase activity from rat brain. (1987) (299)
- Tyrosine hydroxylase in rat brain--cofactor requirements, regional and subcellular distribution. (1972) (293)
- Catecholamine uptake by synaptosomes from rat brain. Structure-activity relationships of drugs with differential effects on dopamine and norepinephrine neurons. (1971) (287)
- Prefrontal cortical dendritic spine pathology in schizophrenia and bipolar disorder. (2014) (285)
- Kainic acid stimulates excitatory amino acid neurotransmitter release at presynaptic receptors (1982) (272)
- Specific binding of [3H]kainic acid to receptor sites in rat brain. (1979) (270)
- Memory impairments following basal forebrain lesions (1985) (262)
- Antioxidants protect against glutamate-induced cytotoxicity in a neuronal cell line. (1989) (260)
- TYROSINE HYDROXYLASE IN RAT BRAIN: DEVELOPMENTAL CHARACTERISTICS (1972) (259)
- Lesion of striatal neurones with kainic acid provides a model for Huntington's chorea. (1976) (250)
- The neurobiologie consequences of down syndrome (1986) (246)
- Dose-finding trial of D-cycloserine added to neuroleptics for negative symptoms in schizophrenia. (1995) (245)
- The distribution and orientation of noradrenergic fibers in neocortex of the rat: An immunofluorescence study (1978) (244)
- The NMDA receptor glycine modulatory site: a therapeutic target for improving cognition and reducing negative symptoms in schizophrenia (2004) (241)
- Ontogenetic development of kainate neurotoxicity: correlates with glutamatergic innervation. (1978) (235)
- DEVELOPMENT OF THE UPTAKE AND STORAGE OF L‐[3H]NOREPINEPHRINE IN THE RAT BRAIN (1971) (234)
- Markers of glutamatergic neurotransmission and oxidative stress associated with tardive dyskinesia. (1998) (228)
- Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia (2017) (226)
- D-serine added to clozapine for the treatment of schizophrenia. (1999) (223)
- Review of the toxicology of chlorpyrifos with an emphasis on human exposure and neurodevelopment. (2008) (218)
- Influence of cortico-striatal afferents on striatal kainic acid neurotoxicity (1978) (215)
- Ontogenetic development of [3H]naloxone binding in rat brain (1976) (211)
- DOPAMINE‐β‐HYDROXYLASE IN THE RAT BRAIN: DEVELOPMENTAL CHARACTERISTICS (1972) (210)
- The role of brain dopamine in behavioral regulation and the actions of psychotropic drugs. (1970) (209)
- The GABA-glutamate connection in schizophrenia: which is the proximate cause? (2004) (198)
- Glutamate and related acidic excitatory neurotransmitters: from basic science to clinical application (1987) (193)
- Increased glutamatergic neurotransmission and oxidative stress after alcohol withdrawal. (1998) (192)
- Neonatal lesions of the basal forebrain cholinergic neurons result in abnormal cortical development. (1988) (188)
- Reversal of long-term locomotor abnormalities in the kainic acid model of Huntington's disease by day 18 fetal striatal implants. (1983) (188)
- Selective destruction of neurons by a transmitter agonist (1977) (187)
- Gene knockout of glycine transporter 1: characterization of the behavioral phenotype. (2004) (186)
- D-cycloserine added to clozapine for patients with schizophrenia. (1996) (185)
- Excitatory amino acid analogues: Neurotoxicity and seizures (1982) (185)
- Histological and neurochemical effects of fetal treatment with methylazoxymethanol on rat neocortex in adulthood (1979) (184)
- The differential effect of right versus left hemispheric cerebral infarction on catecholamines and behavior in the rat (1980) (184)
- The Nagging Question of the Function ofN-Acetylaspartylglutamate (1997) (184)
- Kainic acid selectively stimulates the release of endogenous excitatory acidic amino acids. (1983) (181)
- Dopaminergic dysfunction in tourette syndrome (1982) (181)
- Direct observation of the agonist-specific regional vulnerability to glutamate, NMDA, and kainate neurotoxicity in organotypic hippocampal cultures (1991) (178)
- Structure-activity relations for the neurotoxicity of kainic acid derivatives and glutamate analogues (1978) (175)
- Microinjection of kainic acid into the rat hippocampus. (1978) (174)
- Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction (2013) (170)
- The NMDA receptor 'glycine modulatory site' in schizophrenia: D-serine, glycine, and beyond. (2015) (163)
- Major innervation of newborn rat cortex by monoaminergic neurons. (1977) (162)
- Glutamatergic synaptic dysregulation in schizophrenia: therapeutic implications. (2012) (161)
- The intra-cortical trajectory of the coeruleo-cortical projection in the rat: A tangentially organized cortical afferent (1981) (161)
- The Effects of Various Salts, Temperature, and the Alkaloids Veratridine and Batrachotoxin on the Uptake of [3H] Dopamine into Synaptosomes from Rat Striatum (1974) (160)
- Neuroplasticity signaling pathways linked to the pathophysiology of schizophrenia (2011) (160)
- Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior (2008) (160)
- Intracellular Modulation of NMDA Receptor Function by Antipsychotic Drugs (2000) (155)
- Platelet serotonin, a possible marker for familial autism (1991) (155)
- Regulation of neocortical muscarinic receptors: effects of drug treatment and lesions (1982) (153)
- Galantamine, a cholinesterase inhibitor that allosterically modulates nicotinic receptors: effects on the course of Alzheimer’s disease (2001) (153)
- Biochemical aspects of neurotransmission in the developing brain. (1977) (153)
- Neurotoxic action of kainic acid. (1983) (153)
- Ultrastructural demonstration of noradrenergic synapses in the rat central nervous system by dopamine-beta-hydroxylase immunocytochemistry. (1981) (150)
- Neurochemical sequelae of kainate injections in corpus striatum and substantia nigra of the rat. (1977) (148)
- Neurochemical aspects of the ontogenesis of cholinergic neurons in the rat brain (1976) (145)
- N-Acetylaspartylglutamate: possible role as the neurotransmitter of the lateral olfactory tract. (1985) (144)
- Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior (2010) (142)
- Low Cerebrospinal Fluid Glutamate and Glycine in Refractory Affective Disorder (2007) (141)
- Glutamate hypothesis in schizophrenia (2019) (140)
- Heterogeneity of sodium‐dependent excitatory amino uptake mechanisms in rat brain (1986) (132)
- Kainic acid: neurotoxic effects after intraocular injection. (1977) (132)
- Cell Selective Conditional Null Mutations of Serine Racemase Demonstrate a Predominate Localization in Cortical Glutamatergic Neurons (2012) (130)
- Rat brain N-acetylated alpha-linked acidic dipeptidase activity. Purification and immunologic characterization. (1990) (129)
- Anatomical predictors of behavioral recovery following fetal striatal transplants (1986) (129)
- Mind glue: implications of glial cell biology for psychiatry. (2000) (129)
- The Rise and Fall of the d-Serine-Mediated Gliotransmission Hypothesis (2016) (129)
- NMDA receptor function, neuroplasticity, and the pathophysiology of schizophrenia. (2004) (124)
- Rotational behaviour in rats with unilateral striatal kainic acid lesions: A behavioural model for studies on intact dopamine receptors (1979) (121)
- N-acetylaspartylglutamate: an endogenous peptide with high affinity for a brain "glutamate" receptor. (1983) (121)
- Improved cognition in Alzheimer's disease with short-term D-cycloserine treatment. (1999) (119)
- Trial of d-α-tocopherol in Huntington's disease (1995) (118)
- Trial of d-α-tocopherol in Huntington's disease (1995) (118)
- Ionotropic glutamate receptors as therapeutic targets in schizophrenia. (2002) (115)
- Basal Forebrain Cholinergic Neurons and Alzheimer’s Disease (1988) (115)
- Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis (2017) (114)
- Glutamate carboxypeptidase II is expressed by astrocytes in the adult rat nervous system (1999) (114)
- Clinical, neuropathologic and pharmacologic aspects of Huntington's disease: correlates with a new animal model. (1977) (114)
- Cholinergic innervation of mouse forebrain structures (1994) (114)
- AXONAL TRANSPORT OF CATECHOLAMINE SYNTHESIZING AND METABOLIZING ENZYMES (1973) (114)
- Effects of cortical ablation on the neurotoxicity and receptor binding of kainic acid in striatum (1979) (112)
- THE DISTRIBUTION AND PROPERTIES OF THE NONSPECIFIC N‐METHYLTRANSFERASE IN BRAIN (1973) (110)
- Basal forebrain lesions produce a dissociation of trial-dependent and trial-independent memory performance (1985) (110)
- Scientific approaches to Huntington's disease. (1984) (109)
- Reductions in acidic amino acids andN-acetylaspartylglutamate in amyotrophic lateral sclerosis CNS (1991) (108)
- DOPA decar☐ylase in the developing rat brain (1972) (108)
- Uptake and Subcellular Localization of Neurotransmitters in the Brain (1970) (108)
- Ontogeny of Neurochemical Markers for Noradrenergic, GABAergic and Cholinergic Neurons in Neocortex Lesioned with Methylazoxymethanol Acetate (1980) (107)
- Delayed Protection by MK‐801 and Tetrodotoxin in a Rat Organotypic Hippocampal Culture Model of Ischemia (1994) (105)
- Co‐localization of N‐acetyl‐aspartyl‐glutamate in central cholinergic, noradrenergic, and serotonergic neurons (1987) (105)
- Ultrastructural analysis of kainic acid lesion to cerebellar cortex (1980) (103)
- Serine racemase deletion disrupts memory for order and alters cortical dendritic morphology (2011) (102)
- Folylpoly-gamma-glutamate carboxypeptidase from pig jejunum. Molecular characterization and relation to glutamate carboxypeptidase II. (1998) (101)
- Characterization of specific, high-affinity binding sites for l-[3H]glutamic acid in rat brain membranes (1980) (101)
- Characterization of [3H]hemicholinium-3 binding associated with neuronal choline uptake sites in rat brain membranes (1985) (100)
- d-Serine and Serine Racemase are Localized to Neurons in the Adult Mouse and Human Forebrain (2014) (99)
- Striatal opiate receptors: pre- and postsynaptic localization. (1980) (99)
- Local and distant neuronal degeneration following intrastriatal injection of kainic acid. (1980) (99)
- A controlled trial of idebenone in Huntington's disease (1996) (97)
- Kainic acid-induced lipid peroxidation: protection with butylated hydroxytoluene and U78517F in primary cultures of cerebellar granule cells (1993) (97)
- Immunocytochemical localization of the N‐acetyl‐aspartyl‐glutamate (NAAG) hydrolyzing enzyme N‐acetylated α‐linked acidic dipeptidase (NAALADase) (1992) (97)
- Effects of anaesthetics and anticonvulsants on the action of kainic acid in the rat hippocampus. (1978) (95)
- Excitatory Amino Acid Receptors (1980) (95)
- Evidence for a hippocampal-septal glutamatergic pathway in the rat (1979) (94)
- Serine Racemase Deletion Protects Against Cerebral Ischemia and Excitotoxicity (2010) (94)
- Excitatory amino acids in amyotrophic lateral sclerosis: An update (1991) (93)
- Kainic acid induces apoptosis in neurons (1996) (92)
- Moral Issues of Human-Non-Human Primate Neural Grafting (2005) (91)
- Hydrolysis of the Brain Dipeptide N‐Acetyl‐l‐Aspartyl‐l‐Glutamate: Subcellular and Regional Distribution, Ontogeny, and the Effect of Lesions on N‐Acetylated‐α‐Linked Acidic Dipeptidase Activity (1988) (91)
- Cortical Degeneration with Swollen Chromatolytic Neurons: Its Relationship to Pick's Disease (1986) (91)
- Detection of the effects of dopamine receptor supersensitivity using pharmacological MRI and correlations with PET (2000) (89)
- Isolation and expression of a rat brain cDNA encoding glutamate carboxypeptidase II. (1998) (88)
- Inhibition of [3H]kainic acid receptor binding by divalent cations correlates with ion affinity for the calcium channel (1987) (88)
- The immunocytochemical localization of N-acetylaspartyl glutamate, its hydrolysing enzyme NAALADase, and the NMDAR-1 receptor at a vertebrate neuromuscular junction (1995) (87)
- Selective cholinergic neurotoxin: AF64A's effects in rat striatum (1984) (86)
- Use it or lose it--do effortful mental activities protect against dementia? (2003) (85)
- Molecular characterization of human brain N-acetylated alpha-linked acidic dipeptidase (NAALADase). (1998) (85)
- Developmental time course and ionic dependence of kainate-mediated toxicity in rat cerebellar granule cell cultures. (1991) (85)
- The NMDA receptor co-agonists, d-serine and glycine, regulate neuronal dendritic architecture in the somatosensory cortex (2012) (83)
- Enhanced NAD(P)H:Quinone Reductase Activity Prevents Glutamate Toxicity Produced by Oxidative Stress (1991) (83)
- The immunohistochemical demonstration of noradrenergic neurons in the rat brain: The use of homologous antiserum to dopamine-β-hydroxylase (1977) (83)
- Selective release ofN-acetylaspartylglutamate from rat optic nerve terminals in vivo (1990) (83)
- Long-term sequelae of striatal kainate lesion (1978) (83)
- Primary Degenerative Dementia Without Alzheimer Pathology (1986) (82)
- Neuroanatomical localization and quantification of amyloid precursor protein mRNA by in situ hybridization in the brains of normal, aneuploid, and lesioned mice. (1988) (81)
- The neurobiology of N-acetylaspartylglutamate. (1988) (80)
- Visualization of central noradrenergic neurons in thick sections by the unlabeled antibody method: a transmitter-specific Golgi image. (1978) (80)
- Down syndrome, Alzheimer's disease and the trisomy 16 mouse (1988) (79)
- N-acetyl-aspartylglutamate modulation of N-methyl-D-aspartate-stimulated [3H]norepinephrine release from rat hippocampal slices. (1993) (78)
- AF64A: An Active Site Directed Irreversible Inhibitor of Choline Acetyltransferase (1985) (78)
- Decreased Cortical Glucose Utilization after Ibotenate Lesion of the Rat Ventromedial Globus Pallidus (1984) (78)
- Glutamatergic neurotransmission involves structural and clinical deficits of schizophrenia (1998) (77)
- Idebenone attenuates neuronal degeneration induced by intrastriatal injection of excitotoxins (1990) (77)
- Calcium-dependent glutamate cytotoxicity in a neuronal cell line (1988) (77)
- Methylazoxymethanol treatment of fetal rats results in abnormally dense noradrenergic innervation of neocortex. (1979) (77)
- A long-acting cholinesterase inhibitor reverses spatial memory deficits in mice (1988) (77)
- The potential for muscarinic receptor subtype-specific pharmacotherapy for Alzheimer's disease. (1991) (77)
- Ube3a mRNA and protein expression are not decreased in Mecp2 R168X mutant mice (2007) (75)
- Glutamate Neurotoxicity and the Inhibition of Protein Synthesis in the Hippocampal Slice (1991) (74)
- Dipeptides of glutamate and aspartate may be endogenous neuroexcitants in the rat hippocampal slice (1985) (74)
- Anatomic localization of cholecystokinin receptors to the pyloric sphincter. (1984) (73)
- EFFECTS OF KAINIC ACID ON ION DISTRIBUTION AND ATP LEVELS OF STRIATAL SLICES INCUBATED IN VITRO (1978) (72)
- Chemical and pharmacological characterization of galanthamine, an acetylcholinesterase inhibitor, and its derivatives. A potential application in Alzheimer's disease? (1992) (71)
- Identity of Endogenous NMDAR Glycine Site Agonist in Amygdala Is Determined by Synaptic Activity Level (2013) (71)
- Substance use disorders and schizophrenia: A question of shared glutamatergic mechanisms (2006) (71)
- Cytotoxic lesions and the development of transmitter systems (1982) (71)
- Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia (2010) (71)
- Effects of continuous infusion of cholinergic drugs on memory impairment in rats with basal forebrain lesions. (1989) (70)
- NAAG Reduces NMDA Receptor Current in CA1 Hippocampal Pyramidal Neurons of Acute Slices and Dissociated Neurons (2005) (70)
- Developmental expression of somatostatin in mouse brain. II. In situ hybridization. (1990) (70)
- Enhanced astrocytic D-serine underlies synaptic damage after traumatic brain injury (2017) (70)
- N-acetylaspartylglutamate, N-acetylaspartate, and N-acetylated alpha-linked acidic dipeptidase in human brain and their alterations in Huntington and Alzheimer's diseases. (1997) (70)
- Calcium‐Dependent Evoked Release of N[3H]Acetylaspartylglutamate from the Optic Pathway (1988) (69)
- Rapid in vitro modulation of [3H]hemicholinium-3 binding sites in rat striatal slices. (1987) (69)
- Phylogenetic distribution of [3H]kainic acid receptor binding sites in neuronal tissue (1980) (67)
- Loss of striatal serotonin synaptic receptor binding induced by kainic acid lesions: correlations with Huntington's Disease1 (1977) (67)
- Kainate induces apoptosis in neurons (1996) (66)
- Developmental expression of somatostatin in mouse brain. I. Immunocytochemical studies. (1990) (66)
- Neurogenesis of the basal forebrain in euploid and trisomy 16 mice: An animal model for developmental disorders in down syndrome (1989) (64)
- Quantitative in vivo 1H nuclear magnetic resonance spectroscopic imaging of neuronal loss in rat brain (1995) (63)
- Immunohistochemical evidence for phenylethanolamine-N-methyltransferase-positive/tyrosine hydroxylase-negative neurones in the retina and the posterior hypothalamus of the rat (1985) (63)
- Trial of d-alpha-tocopherol in Huntington's disease. (1995) (63)
- Quisqualate‐sensitive, chloride‐dependent transport of glutamate into rat brain synaptosomes (1987) (63)
- Cholinergic lesion of the striatum impairs acquisition and retention of a passive avoidance response. (1984) (63)
- Galanthamine, an acetylcholinesterase inhibitor: A time course of the effects on performance and neurochemical parameters in mice (1989) (63)
- Somatostatin is not co-localized in cholinergic neurons innervating the rat cerebral cortex-hippocampal formation (1982) (63)
- Cerebrospinal fluid acetylcholinesterase activity in senile dementia of the Alzheimer type (1985) (63)
- Analogue interactions with the brain receptor labeled by [3H]kainic acid (1983) (61)
- Rapid regulation of [3H]hemicholinium-3 binding sites in the rat brain (1986) (60)
- Basal forebrain neurons provide major cholinergic innervation of primate neocortex (1986) (60)
- GABA receptor binding in rat striatum: Localization and effects of denervation (1977) (59)
- Selective immunocytochemical staining of mitral cells in rat olfactory bulb with affinity purified antibodies against N-acetyl-aspartyl-glutamate (1987) (59)
- Newborn basal forebrain lesions disrupt cortical cytodifferentiation as visualized by rapid Golgi staining. (1991) (59)
- Site-directed mutagenesis of predicted active site residues in glutamate carboxypeptidase II. (1999) (59)
- Morphologic and neurochemical studies of embryonic brain development in murine trisomy 16. (1984) (58)
- Noradrenergic innervation patterns in three regions of medial cortex: An immunofluorescence characterization (1979) (57)
- Head and trunk neural crest in vitro: autonomic neuron differentiation. (1980) (57)
- Dopamine-β-hydroxylase in rat submandibular ganglion cells which lack norepinephrine (1978) (56)
- Dysregulated protocadherin-pathway activity as an intrinsic defect in iPSC-derived cortical interneurons from patients with schizophrenia (2019) (56)
- Reduced glycine transporter type 1 expression leads to major changes in glutamatergic neurotransmission of CA1 hippocampal neurones in mice (2005) (54)
- Characteristics of chloride-dependent incorporation of glutamate into brain membranes argue against a receptor binding site (1987) (54)
- Lateralization of catecholaminergic and behavioral response to cerebral infarction in the rat. (1979) (53)
- Kainic acid neurotoxicity and seizures (1981) (53)
- Evidence for the existence of putative dopamine-, adrenaline- and noradrenaline-containing vagal motor neurons in the brainstem of the rat (1984) (53)
- Effects of sustained seizures produced by intrahippocampal injection of kainic acid on noradrenergic neurons: evidence for local control of norepinephrine release. (1980) (53)
- Genetic linkage in the mouse of genes involved in Down syndrome and Alzheimer's disease in man. (1987) (52)
- Regional heterogeneity of choline acetyltransferase activity in primate neocortex (1984) (52)
- Effects of over- and under-expression of Cu,Zn-superoxide dismutase on the toxicity of glutamate analogs in transgenic mouse striatum (1998) (52)
- Methylazoxymethanol acetate ablation of mouse cerebellar granule cells: effects on synaptic neurochemistry. (1982) (51)
- Characterization of a glutamic acid neurotransmitter binding site on neuroblastoma hybrid cells. (1984) (51)
- Efferent and afferent connections of mouse sensory-motor cortex following cholinergic deafferentation at birth. (1991) (51)
- Tardive dyskinesia and substrates of energy metabolism in CSF. (1995) (51)
- An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia (2016) (51)
- Functional magnetic resonance imaging studies of schizophrenic patients during word production: effects of d-cycloserine (2005) (50)
- N-acetylated alpha-linked acidic dipeptidase is expressed by non-myelinating Schwann cells in the peripheral nervous system (1995) (50)
- Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II 1 Published on the World Wide Web on 24 April 1998. 1 (1998) (50)
- iPSC-derived homogeneous populations of developing schizophrenia cortical interneurons have compromised mitochondrial function (2019) (50)
- Ontogenesis of N-acetyl-aspartate and N-acetyl-aspartyl-glutamate in rat brain. (1984) (49)
- Kainic acid: insights into excitatory mechanisms causing selective neuronal degeneration. (1987) (49)
- The effects of N-acetylated alpha-linked acidic dipeptidase (NAALADase) inhibitors on [3H]NAAG catabolism in vivo (1989) (48)
- Neuronal d-serine regulates dendritic architecture in the somatosensory cortex (2012) (48)
- Effects of Kainic Acid on High‐Energy Metabolites in the Mouse Striatum (1982) (47)
- Distribution of N-acetylaspartylglutamate immunoreactivity in human brain and its alteration in neurodegenerative disease (1997) (46)
- Age-related recurrence of basal forebrain lesion-induced cholinergic deficits (1987) (46)
- Dissociation of nitric oxide generation and kainate-mediated neuronal degeneration in primary cultures of rat cerebellar granule cells (1992) (46)
- Cooperative interactions at [3H]kainic acid binding sites in rat and human cerebellum. (1979) (46)
- Effects of different doses of galanthamine, a long-acting acetylcholinesterase inhibitor, on memory in mice (2005) (46)
- Automated measurement of stereotypic behavior in rats. (1983) (45)
- Clinical symptomatology, CSF neurotransmitter metabolites, and serum haloperidol levels in Tourette syndrome. (1982) (45)
- Glutamate Carboxypeptidase II Gene Expression in the Human Frontal and Temporal Lobe in Schizophrenia (2004) (45)
- Cell-based interventions for neurologic conditions (2008) (45)
- Developmental regulation of adult cortical morphology and behavior: An animal model for mental retardation (1994) (44)
- Enhancement of NMDA receptor-mediated neurotoxicity in the hippocampal slice by depolarization and ischemia (1991) (44)
- Excitatory Amino Acid Neurotoxins (1982) (44)
- History of the Concept of Disconnectivity in Schizophrenia (2016) (43)
- Lesions of the basal forebrain alter stimulus‐evoked metabolic activity in mouse somatosensory cortex (1989) (43)
- The characterization of the specific binding of [3H]-N- acetylaspartylglutamate to rat brain membranes (1985) (42)
- Localization of receptors for kainic acid on neurons in the innernuclear layer of retina (1979) (42)
- Enhanced local processing of dynamic visual information in autism: Evidence from speed discrimination (2012) (42)
- Transient postnatal elevation of serotonin levels in mouse neocortex. (1988) (41)
- Subcellular localization of dopamine beta-hydroxylase and endogenous norepinephrine in the rat hypothalamus. (1974) (41)
- Evoked release of aspartate and glutamate: disparities between prelabeling and direct measurement (1983) (41)
- Genetically epilepsy-prone rats have increased brain regional activity of an enzyme which liberates glutamate from N-acetyl-aspartyl-glutamate (1992) (41)
- Glutamate cytotoxicity in a neuronal cell line is blocked by membrane depolarization (1988) (40)
- Laminar distribution of cholinergic markers in neocortex: Effects of lesions (1981) (40)
- Specific binding of [3H]+/- 2-amino-7-phosphono heptanoic acid to rat brain membranes in vitro. (1983) (40)
- Dissociation between the excitatory and "excitotoxic" effects of quinolinic acid analogs on the striatal cholinergic interneuron. (1985) (40)
- Striosomal organization of cholinergic and dopaminergic uptake sites and cholinergic M1 receptors in the adult human striatum: a quantitative receptor autoradiographic study (1990) (40)
- Synaptosomal Transport of Radiolabel from N‐Acetyl‐Aspartyl‐[3H]Glutamate Suggests a Mechanism of Inactivation of an Excitatory Neuropeptide (1986) (40)
- N-Acetylaspartylglutamate (NAAG) protects against rat striatal quinolinic acid lesions in vivo (1997) (39)
- Genetic mapping and analysis of somatostatin expression in Snell dwarf mice. (1988) (39)
- Brain Serotonin2 and Serotonin1A Receptors Are Altered in the Congenitally Hyperammonemic Sparse Fur Mouse (1992) (39)
- Astroglial Versus Neuronal D-Serine: Check Your Controls! (2017) (39)
- Quisqualate selectively inhibits a brain peptidase which cleaves N-acetyl-L-aspartyl-L-glutamate in vitro. (1986) (39)
- Behavioral and Neurotransmitter Changes in the Urease-Infused Rat: A Model of Congenital Hyperammonemia (1986) (39)
- Cerebrospinal fluid correlates of depression in Huntington's disease. (1988) (38)
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- International journal of developmental neuroscience forthcoming papers (1994) (0)
- 1193 THE UREASE INFUSED RAT AS A MODEL OF INBORN ERRORS OF UREA SYNTHESIS (1985) (0)
- Time-dependent effects of haloperidol on glutamine and GABA homeostasis and astrocyte activity in the rat brain (2013) (0)
- 276. The role of glutamate and HVA in schizophrenic symptomatology (1998) (0)
- Serine Racemase Expression by Striatal Neurons (2020) (0)
- Chapter 31 – Introduction (2015) (0)
- December 15, 2003 (2007) (0)
- Excitatory amino acid receptor interactions of a novel alpha-phosphinic acid analogue of alpha-methylaspartic acid. (1984) (0)
- Use of agonists of the binding site or glycine uptake inhibitor of the glycine for treating neuropsychiatric disorders. (1999) (0)
- The role of glutmate and HVA in schizophrenic symptomatology (1998) (0)
- 57 Neural network and coherence differentiation of hypnotic susceptibility (1998) (0)
- Synthesis of C-analogues of kainic acids and their interaction with brain receptors. (1984) (0)
- Funding of NIMH extramural research. (1994) (0)
- Notes and Comment Investigating locomotion abnonnalities in animal modelsof extrapyramidal disorders: A commentary (1984) (0)
- Neurotransmitter actions in the vertebrate nervous system Edited by M. A. Rogawski and J. L. Barker. New York: Plenum Press. (1985). 511 pp. $69.50 (1986) (0)
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