Josephine Forbes
Australian scientist
Josephine Forbes's AcademicInfluence.com Rankings
Download Badge
Chemistry
Josephine Forbes's Degrees
- PhD Chemical Engineering University of Melbourne
Why Is Josephine Forbes Influential?
(Suggest an Edit or Addition)According to Wikipedia, Josephine Forbes is an Australian scientist specialising in the study of glycation and diabetes. She has been studying diabetes since 1999 and has worked at Royal Children's Hospital, University of Melbourne and Baker Heart and Diabetes Institute in Melbourne Australia. Since 2012 she has led the Glycation and Diabetes team at Mater Research which is a world-class medical research institute based at South Brisbane, and part of the Mater Group. Josephine is program leader for Mater's Chronic Disease Biology and Care theme, building greater understanding of the biological basis of a broad range of chronic diseases, and developing preventative strategies and innovative treatments to improve patient outcomes. Josephine and her team focus on how advanced glycation contributes to the pathogenesis of diabetes and its complications such as kidney disease.
Josephine Forbes's Published Works
Published Works
- Mechanisms of diabetic complications. (2013) (1866)
- Oxidative Stress as a Major Culprit in Kidney Disease in Diabetes (2008) (1102)
- Advanced glycation end products cause epithelial-myofibroblast transdifferentiation via the receptor for advanced glycation end products (RAGE). (2001) (440)
- A Breaker of Advanced Glycation End Products Attenuates Diabetes‐Induced Myocardial Structural Changes (2003) (432)
- Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy (2012) (410)
- RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes. (2009) (394)
- Receptor for Advanced Glycation End Products (RAGE) Deficiency Attenuates the Development of Atherosclerosis in Diabetes (2008) (382)
- Brain Atrophy in Type 2 Diabetes (2013) (367)
- High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus (2009) (351)
- Characterization of Renal Angiotensin-Converting Enzyme 2 in Diabetic Nephropathy (2003) (347)
- AGE, RAGE, and ROS in diabetic nephropathy. (2007) (339)
- Role of advanced glycation end products in diabetic nephropathy. (2003) (333)
- Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway (2008) (327)
- Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis. (2004) (306)
- Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy. (2002) (289)
- The breakdown of pre‐existing advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes (2003) (266)
- Mitochondrial dysfunction in diabetic kidney disease (2018) (263)
- Synbiotics Easing Renal Failure by Improving Gut Microbiology (SYNERGY): A Randomized Trial. (2016) (247)
- Connective tissue growth factor plays an important role in advanced glycation end product-induced tubular epithelial-to-mesenchymal transition: implications for diabetic renal disease. (2006) (244)
- Effects of SGLT2 Inhibition in Human Kidney Proximal Tubular Cells—Renoprotection in Diabetic Nephropathy? (2013) (237)
- Modulation of soluble receptor for advanced glycation end products by angiotensin-converting enzyme-1 inhibition in diabetic nephropathy. (2005) (201)
- Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress (2014) (196)
- Diabetic nephropathy: where hemodynamics meets metabolism. (2007) (169)
- Renoprotective effects of a novel inhibitor of advanced glycation (2001) (164)
- Ischemic acute renal failure: long-term histology of cell and matrix changes in the rat. (2000) (164)
- Interactions between angiotensin II and NF-kappaB-dependent pathways in modulating macrophage infiltration in experimental diabetic nephropathy. (2004) (156)
- Renal connective tissue growth factor induction in experimental diabetes is prevented by aminoguanidine. (2002) (154)
- Attenuation of extracellular matrix accumulation in diabetic nephropathy by the advanced glycation end product cross-link breaker ALT-711 via a protein kinase C-alpha-dependent pathway. (2004) (151)
- Advanced glycation of apolipoprotein A-I impairs its anti-atherogenic properties (2007) (146)
- Angiotensin type 2 receptor is expressed in the adult rat kidney and promotes cellular proliferation and apoptosis. (2000) (137)
- Rosiglitazone Attenuates Atherosclerosis in a Model of Insulin Insufficiency Independent of Its Metabolic Effects (2005) (136)
- Interactions between renin angiotensin system and advanced glycation in the kidney. (2005) (131)
- Advanced Glycation End Products Are Direct Modulators of β-Cell Function (2011) (130)
- Accelerated nephropathy in diabetic apolipoprotein e-knockout mouse: role of advanced glycation end products. (2004) (129)
- The effect of salsalate on insulin action and glucose tolerance in obese non-diabetic patients: results of a randomised double-blind placebo-controlled study (2009) (120)
- Combination therapy with the advanced glycation end product cross-link breaker, alagebrium, and angiotensin converting enzyme inhibitors in diabetes: synergy or redundancy? (2007) (118)
- Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy. (2010) (118)
- Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice (2016) (117)
- Ubiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetes. (2012) (116)
- Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs. (2008) (114)
- Coenzyme Q10 attenuates diastolic dysfunction, cardiomyocyte hypertrophy and cardiac fibrosis in the db/db mouse model of type 2 diabetes (2012) (113)
- Targeted reduction of advanced glycation improves renal function in obesity. (2011) (108)
- Advanced glycation end products and diabetic nephropathy. (2005) (107)
- Modulation of nephrin in the diabetic kidney: association with systemic hypertension and increasing albuminuria (2002) (98)
- The cross-link breaker, N-phenacylthiazolium bromide prevents vascular advanced glycation end-product accumulation (2000) (98)
- Nox‐4 deletion reduces oxidative stress and injury by PKC‐α‐associated mechanisms in diabetic nephropathy (2014) (88)
- Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes. (2016) (88)
- Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease. (2003) (86)
- Advanced glycation end-products induce vascular dysfunction via resistance to nitric oxide and suppression of endothelial nitric oxide synthase (2010) (85)
- Diet low in advanced glycation end products increases insulin sensitivity in healthy overweight individuals: a double-blind, randomized, crossover trial. (2016) (84)
- Increased renal vascular endothelial growth factor and angiopoietins by angiotensin II infusion is mediated by both AT1 and AT2 receptors. (2003) (84)
- Methylglyoxal, cognitive function and cerebral atrophy in older people. (2013) (83)
- Interactions Between Advanced Glycation End-Products (AGE) and their Receptors in the Development and Progression of Diabetic Nephropathy – are these Receptors Valid Therapeutic Targets (2009) (77)
- Receptor for AGEs (RAGE) blockade may exert its renoprotective effects in patients with diabetic nephropathy via induction of the angiotensin II type 2 (AT2) receptor (2010) (76)
- Circulating high-molecular-weight RAGE ligands activate pathways implicated in the development of diabetic nephropathy. (2010) (75)
- Vascular complications in diabetes: old messages, new thoughts (2017) (74)
- Simultaneous blockade of endothelin A and B receptors in ischemic acute renal failure is detrimental to long-term kidney function. (2001) (74)
- Identification of angiotensin converting enzyme 2 in the rodent retina (2004) (73)
- Dietary glycotoxins exacerbate progression of experimental fatty liver disease. (2014) (71)
- Temporal renal expression of angiogenic growth factors and their receptors in experimental diabetes: role of the renin–angiotensin system (2005) (70)
- Coming full circle in diabetes mellitus: from complications to initiation (2013) (68)
- Role of the AGE crosslink breaker, alagebrium, as a renoprotective agent in diabetes. (2007) (68)
- Superior renoprotective effects of combination therapy with ACE and AGE inhibition in the diabetic spontaneously hypertensive rat (2003) (66)
- Mitochondria–Power Players in Kidney Function? (2016) (65)
- Type 2 Diabetes, Skin Autofluorescence, and Brain Atrophy (2014) (64)
- A developmental nephron deficit in rats is associated with increased susceptibility to a secondary renal injury due to advanced glycation end-products (2006) (63)
- Effects of High-Density Lipoprotein Elevation With Cholesteryl Ester Transfer Protein Inhibition on Insulin Secretion (2013) (60)
- Heat shock protein expression in diabetic nephropathy. (2008) (58)
- Stress in the kidney is the road to pERdition: is endoplasmic reticulum stress a pathogenic mediator of diabetic nephropathy? (2014) (56)
- Reduced tubular cation transport in diabetes: prevented by ACE inhibition. (2003) (56)
- Dietary advanced glycation end-products aggravate non-alcoholic fatty liver disease (2016) (55)
- Macrophage and myofibroblast involvement in ischemic acute renal failure is attenuated by endothelin receptor antagonists. (1999) (54)
- Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis (2020) (53)
- Targeting advanced glycation endproducts and mitochondrial dysfunction in cardiovascular disease. (2013) (52)
- The Role of Advanced Glycation in Reduced Organic Cation Transport Associated with Experimental Diabetes (2004) (52)
- Processed foods drive intestinal barrier permeability and microvascular diseases (2021) (52)
- Oxidative Stress and Advanced Glycation in Diabetic Nephropathy (2008) (51)
- Development and Progression of Non-Alcoholic Fatty Liver Disease: The Role of Advanced Glycation End Products (2019) (51)
- Advanced glycation end products augment experimental hepatic fibrosis (2013) (49)
- Regional distribution and influence on cognition (2013) (45)
- Mitochondrial Dysfunction and Signaling in Diabetic Kidney Disease: Oxidative Stress and Beyond. (2018) (45)
- Advanced glycation: implications in tissue damage and disease. (2008) (45)
- Early vitamin E supplementation attenuates diabetes-associated vascular dysfunction and the rise in protein kinase C-β in mesenteric artery and ameliorates wall stiffness in femoral artery of Wistar rats (2004) (45)
- Targeting advanced glycation with pharmaceutical agents: where are we now? (2016) (45)
- High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction. (2005) (45)
- SYNbiotics Easing Renal failure by improving Gut microbiologY (SYNERGY): a protocol of placebo-controlled randomised cross-over trial (2014) (43)
- Glucose and glycogen in the diabetic kidney: Heroes or villains? (2019) (42)
- Effects of HDL Elevation with CETP Inhibition on Insulin Secretion (2013) (42)
- Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis (2016) (41)
- Advanced glycation end-products (AGEs) and functionality of reverse cholesterol transport in patients with type 2 diabetes and in mouse models (2012) (41)
- Below the radar: advanced glycation end products that detour "around the side". Is HbA1c not an accurate enough predictor of long term progression and glycaemic control in diabetes? (2005) (41)
- Renal microvascular injury in diabetes: RAGE and redox signaling. (2006) (40)
- Interactions between advanced glycation end-products (AGE) and their receptors in the development and progression of diabetic nephropathy - are these receptors valid therapeutic targets. (2009) (40)
- Deficiency in mitochondrial complex I activity due to Ndufs6 gene trap insertion induces renal disease. (2013) (40)
- Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes (2011) (40)
- Complement C5a Induces Renal Injury in Diabetic Kidney Disease by Disrupting Mitochondrial Metabolic Agility (2019) (39)
- Low‐Molecular Weight Advanced Glycation End Products: Markers of Tissue AGE Accumulation and More? (2005) (39)
- The pleiotropic actions of rosuvastatin confer renal benefits in the diabetic Apo-E knockout mouse. (2010) (38)
- Novel therapeutics for diabetic micro- and macrovascular complications. (2006) (37)
- c-Jun NH2-Terminal Kinase Activity in Subcutaneous Adipose Tissue but Not Nuclear Factor-κB Activity in Peripheral Blood Mononuclear Cells Is an Independent Determinant of Insulin Resistance in Healthy Individuals (2009) (35)
- The effects of valsartan on the accumulation of circulating and renal advanced glycation end products in experimental diabetes. (2004) (34)
- Targeting the AGE‐RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end‐product content (2013) (34)
- Increased risk of cardiovascular disease in Type 1 diabetes: arterial exposure to remnant lipoproteins leads to enhanced deposition of cholesterol and binding to glycated extracellular matrix proteoglycans (2011) (33)
- Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects (2014) (32)
- Advanced Glycation Urinary Protein-Bound Biomarkers and Severity of Diabetic Nephropathy in Man (2011) (32)
- Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy (2014) (30)
- Effect of dietary advanced glycation end products on inflammation and cardiovascular risks in healthy overweight adults: a randomised crossover trial (2017) (30)
- Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes (2017) (29)
- A New Perspective on Therapeutic Inhibition of Advanced Glycation in Diabetic Microvascular Complications: Common Downstream Endpoints Achieved Through Disparate Therapeutic Approaches? (2009) (29)
- Abdominal Obesity and Brain Atrophy in Type 2 Diabetes Mellitus (2015) (29)
- Advanced Glycation End Products and esRAGE Are Associated With Bone Turnover and Incidence of Hip Fracture in Older Men (2018) (28)
- Agents in development for the treatment of diabetic nephropathy (2005) (27)
- The relationship between heat shock protein 72 expression in skeletal muscle and insulin sensitivity is dependent on adiposity. (2010) (26)
- Impact of dietary carbohydrate type and protein–carbohydrate interaction on metabolic health (2021) (26)
- Glycation in diabetic nephropathy (2012) (24)
- A rapid extraction method for glycogen from formalin-fixed liver. (2015) (24)
- Advanced glycation end products as environmental risk factors for the development of type 1 diabetes. (2012) (24)
- Delineating a role for the Mitochondrial Permeability Transition Pore in Diabetic Kidney Disease by targeting Cyclophilin D. (2020) (23)
- Impairment of Liver Glycogen Storage in the db/db Animal Model of Type 2 Diabetes: A Potential Target for Future Therapeutics? (2015) (22)
- Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes (2014) (22)
- Glucose homeostasis can be differentially modulated by varying individual components of a western diet. (2013) (22)
- Receptor for Advanced Glycation End Products (RAGE) in Type 1 Diabetes Pathogenesis (2016) (21)
- Long Term High Protein Diet Feeding Alters the Microbiome and Increases Intestinal Permeability, Systemic Inflammation and Kidney Injury in Mice. (2021) (21)
- Circulating Concentrations of Soluble Receptor for AGE Are Associated With Age and AGER Gene Polymorphisms in Children With Newly Diagnosed Type 1 Diabetes (2014) (20)
- Reversible Angiotensin II-Mediated Albuminuria in Rat Kidneys Is Dynamically Associated with Cytoskeletal Organization (2003) (20)
- Increased liver AGEs induce hepatic injury mediated through an OST48 pathway (2017) (20)
- Tapping into Mitochondria to Find Novel Targets for Diabetes Complications. (2016) (20)
- Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure (2014) (19)
- Modulation of the Cellular Expression of Circulating Advanced Glycation End-Product Receptors in Type 2 Diabetic Nephropathy (2011) (19)
- Endothelin and Endothelin A/B Receptors Are Increased after Ischaemic Acute Renal Failure (2001) (18)
- Preservation of Kidney Function with Combined Inhibition of NADPH Oxidase and Angiotensin-Converting Enzyme in Diabetic Nephropathy (2010) (18)
- Targeting the receptor for advanced glycation end products (RAGE) in type 1 diabetes (2020) (18)
- RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis (2018) (18)
- Diabetic kidney disease: a role for advanced glycation end-product receptor 1 (AGE-R1)? (2016) (18)
- Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction (2017) (18)
- Therapeutic Interruption of Advanced Glycation in Diabetic Nephropathy (2008) (17)
- Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study. (2009) (17)
- Antigen-Encoding Bone Marrow Terminates Islet-Directed Memory CD8+ T-Cell Responses to Alleviate Islet Transplant Rejection (2016) (16)
- Temporal Increases in Urinary Carboxymethyllysine Correlate with Albuminuria Development in Diabetes (2011) (16)
- MKK3 signalling plays an essential role in leukocyte-mediated pancreatic injury in the multiple low-dose streptozotocin model (2008) (16)
- Decrease in Circulating Concentrations of Soluble Receptors for Advanced Glycation End Products at the Time of Seroconversion to Autoantibody Positivity in Children With Prediabetes (2015) (15)
- Tissue inhibitor of the metalloproteinases and renal extracellular matrix accumulation. (1995) (14)
- The effect of a low carbohydrate formula on glycaemia in critically ill enterally-fed adult patients with hyperglycaemia: A blinded randomised feasibility trial. (2019) (14)
- Corrigendum: Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy (2012) (14)
- The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase. (2011) (13)
- Advanced glycation: how are we progressing to combat this web of sugar anomalies in diabetic nephropathy. (2004) (12)
- Ramipril prevents microtubular changes in proximal tubules from streptozotocin diabetic rats (2003) (12)
- Glycaemic variability and its association with enteral and parenteral nutrition in critically ill ventilated patients. (2019) (12)
- Additive effects of hypertension and diabetes on renal cortical expression of PKC-α and -&epsis; and α-tubulin but not PKC-β1 and -β2 (2003) (11)
- Additive effects of hypertension and diabetes on renal cortical expression of PKC-alpha and -epsilon and alpha-tubulin but not PKC-beta 1 and -beta 2. (2003) (11)
- Contrasting association of circulating sCD14 with insulin sensitivity in non-obese and morbidly obese subjects. (2016) (11)
- Advanced Glycation End Products Are Direct Modulators of b -Cell Function (2011) (10)
- Diabetes-Specific Formulae Versus Standard Formulae as Enteral Nutrition to Treat Hyperglycemia in Critically Ill Patients: Protocol for a Randomized Controlled Feasibility Trial (2018) (10)
- The Maillard reaction : interface between aging, nutrition and metabolism (2010) (10)
- Can Advanced Glycation End Product Inhibitors Modulate More than One Pathway to Enhance Renoprotection in Diabetes? (2005) (9)
- A drop in the circulating concentrations of soluble receptor for advanced glycation end products is associated with seroconversion to autoantibody positivity but not with subsequent progression to clinical disease in children en route to type 1 diabetes (2017) (8)
- Antitumor Effects of the Early Maillard Reaction Products (2010) (8)
- Obesity‐induced renal impairment is exacerbated in interleukin‐6‐knockout mice (2012) (7)
- Insulin infusion reduces hepatocyte growth factor in lean humans. (2013) (7)
- Advanced Glycation End Products (AGEs) and Chronic Kidney Disease: Does the Modern Diet AGE the Kidney? (2022) (7)
- Dietary Advanced Glycation End Products Consumption as a Direct Modulator of Insulin Sensitivity in Overweight Humans: A Study Protocol for a Double-Blind, Randomized, Two Period Cross-Over Trial (2015) (6)
- Advanced Glycation, Diabetes, and Dementia (2018) (6)
- N ε -carboxymethyllysine: it's Origin in Selected Foods and its Urinary and Faecal Excretion in Healthy Humans (2010) (6)
- Erratum: Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice (2016) (5)
- Disruption of Glycogen Utilization Markedly Improves the Efficacy of Carboplatin against Preclinical Models of Clear Cell Ovarian Carcinoma (2020) (5)
- Globally elevating the AGE clearance receptor, OST48, does not protect against the development of diabetic kidney disease, despite improving insulin secretion (2019) (5)
- Erratum: Reduction of the accumulation of advanced glycation end products by ACE inhibition in experimental diabetic nephropathy (Diabetes (2000) 51 (3274-3282)) (2002) (5)
- High-density lipoprotein modulates glucose metabolism in patients with type 2 diabetes (2009) (5)
- T-Cell Expression and Release of Kidney Injury Molecule-1 in Response to Glucose Variations Initiates Kidney Injury in Early Diabetes (2021) (5)
- Dicarbonyls in Cola Drinks Sweetened with Sucrose or High Fructose Corn Syrup (2010) (4)
- Genetic characterization of early renal changes in a novel mouse model of diabetic kidney disease. (2019) (4)
- Pivotal role of the AT2 receptor subtype in mediating angiotensin II indiced renal VEGF expression. (2002) (4)
- Attenuation of Diabetes-associated Atherosclerosis with LR-90, a Novel Inhibitor of AGE Formation (2010) (4)
- Soluble RAGE Prevents Type 1 Diabetes Expanding Functional Regulatory T Cells (2022) (4)
- The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition) (2021) (3)
- Renoprotection is afforded by the advanced glycation end product (AGE) cross-link breaker, ALT-711. (2002) (3)
- Report on ISN Forefronts, Melbourne, Australia, 4-7 October 2012: tubulointerstitial disease in diabetic nephropathy. (2013) (3)
- Activation of renal type IV collagenases. (1996) (3)
- Role of oxidative stress in diabetic nephropathy (2011) (2)
- Type 2 Diabetic Cardiomyopathy in db/db Mice is Associated with Progressive Cardiac Fibrosis, Cardiomyocyte Hypertrophy and Oxidative Stress (2008) (2)
- The impact of a modified carbohydrate formula, and its constituents, on glycaemic control and inflammatory markers: A nested mechanistic sub-study. (2021) (2)
- JNK activity in subcutaneous adipose tissue but not NF κ B activity in peripheral blood mononuclear cells is an independent determinant of insulin resistance in healthy individuals. (2009) (2)
- Disparity in the micronutrient content of diets high or low in advanced glycation end products (AGEs) does not explain changes in insulin sensitivity (2017) (2)
- Advanced glycation end products as predictors of renal function in youth with type 1 diabetes (2021) (2)
- Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells (2022) (2)
- Short Duration Alagebrium Chloride Therapy Prediabetes Does Not Inhibit Progression to Autoimmune Diabetes in an Experimental Model (2021) (2)
- Prolyl hydroxylase inhibitors: a breath of fresh air for diabetic kidney disease? (2020) (2)
- Renal intra-mitochondrial glycation drives deficiencies in the activity of manganese superoxide dismutase and complex I of the mitochondrial respiratory chain in diabetes (2005) (2)
- The Renin-Angiotensin System and Advanced Glycation End-products in Diabetic Nephropathy. How Important are these Pathways as Therapeutic Targets? (2010) (2)
- AGEs Fluorescence of Plasma, Urine and Skin Reflects Dietary Exposure to Maillard Products in Formula-fed Infants (2010) (2)
- Circulating Levels of the Soluble Receptor for AGE (sRAGE) during Escalating Oral Glucose Dosages and Corresponding Isoglycaemic i.v. Glucose Infusions in Individuals with and without Type 2 Diabetes (2020) (2)
- Dietary AGEs in the development and progression of chronic kidney disease (2018) (2)
- Pathogenesis of diabetic microvascular complications (2015) (2)
- High Density Lipoprotein Modulates Glucose Metabolism by Multiple Mechanisms (2009) (2)
- Serum 25-hydroxyvitamin D concentrations are associated with nuclear factor kappa-B activity but not with inflammatory markers in healthy normoglycemic adults (2017) (2)
- Thermally Processed Diet-Induced Albuminuria, Complement Activation and Intestinal Permeability Are Attenuated by Resistant Starch in Experimental Diabetes (2021) (1)
- , Karin of Its Metabolic Effects Rosiglitazone Attenuates Atherosclerosis in a Model of Insulin Insufficiency Independent (2005) (1)
- Direct anti-atherogenic properties of PPAR alpha and PPAR gamma agonists (2005) (1)
- Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model (2015) (1)
- Regulation of renal receptor for advanced glycation end products (RAGE) via paracrine estrogens (2010) (1)
- The SGLT2 Inhibitor, Empagliflozin, Attenuates Some Markers of Renal Fibrosis without Improving Albuminuria in Diabetic Db/Db Mice (2016) (1)
- Expansion of Functional Regulatory T Cells Using Soluble RAGE Prevents Type 1 Diabetes (2020) (1)
- Chemistry of Pigments as Intermediate of Melanoidins (2010) (1)
- Glyoxalase-1 Inhibition Leads to Podocyte Insulin Resistance and Features Resembling Diabetic Kidney Disease (2014) (1)
- Glyceraldehydes-derived Advanced Glycation End Products Decrease White Adipose Tissue Weight and Downregulate Leptin, Adiponectin, and Macrophage Marker (2010) (1)
- Nutrition support and glycaemic variability in critically ill patients (2018) (1)
- DOES COMBINED BLOCKADE OF THE RAS AND AGE FORMATION CONFER SUPERIOR RETROPROTECTION IN A HYPERTENSIVE MODEL OF DIABETIC NEPHROPATHY (2002) (1)
- The renal pathogenicity of dietary glycotoxins is mediated via the receptor for advanced glycation end products (RAGE) (2008) (1)
- Ager1 overexpression in glomerular podocytes results in renal disease which is exacerbated by diabetes (2014) (1)
- Complement C5a induces renal injury in diabetic kidney disease via mitochondrial reprogramming (2019) (1)
- Glycation Lowering Therapies Differ in Their Mode of Action in Experimental Autoimmune Diabetes (2014) (1)
- Absence of RAGE protects from atherosclerosis in diabetes RAGE DEFICIENCY ATTENUATES THE DEVELOPMENT OF ATHEROSCLEROSIS IN DIABETES (2008) (1)
- Screening of AGE Inhibitors by Antibody Library (2010) (1)
- LATE INTERVENTION WITH PYRIDOXAMINE RETARDS PROGRESSION OF ATHEROSCLEROSIS IN DIABETIC APOE KNOCKOUT MICE (2004) (1)
- Response to Comment on: Thallas-Bonke et al. (2008) Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product–Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-α–Dependent Pathway: Diabetes 57:460–469, 2008 (2008) (1)
- Kidney disease risk factors do not explain impacts of low dietary protein on kidney function and structure (2021) (1)
- Does combined blockade of RAS and advanced glycation end-product formation confer superior renoprotection in a hypertensive model of diabetic nephropathy? (2002) (1)
- Glycated Proteins Bind to ERM Proteins and Modulate their Actions (2010) (1)
- Review for "Increased tissue factor activity promotes thrombin generation at type 1 diabetes onset in children" (2020) (1)
- Novel Maillard Pigments Formed from Furfural and Xylose with Lysine Under Weakly Acidic Conditions (2010) (1)
- Some Natural Products Extracts Inhibit the Formation of N(Carboxymetyl)arginine (2010) (1)
- Diabetic Nephropathy: Current and Novel Therapeutic Approaches to Prevent Its Development and Progression (2012) (1)
- Advanced Glycation End Products and Inflammation in Type 1 Diabetes Development (2022) (1)
- Increased liver AGEs induce hepatic injury mediated through an OST48 pathway (2017) (1)
- Erratum to: Receptor for advanced glycation end-products (RAGE) provides a link between genetic susceptibility and environmental factors in type 1 diabetes (2011) (1)
- Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice (2014) (1)
- Beneficial effects on albuminuria in experimental diabetes with ALT 946, a novel inhibitor of advanced glycation (2000) (0)
- SAT-104 USING THE GEOMETRIC FRAMEWORK TO EXPLORE THE EFFECTS OF DIETARY MACRONUTRIENT CONSUMPTION ON KIDNEY HEALTH IN AGEING (2019) (0)
- Artificial activation of matrix metalloproteinases. (1997) (0)
- Mitochondrial Dysfunction Defines a Population of Young People with Type 1 Diabetes At Risk of Kidney Disease (2017) (0)
- Going in Early: Hypoxia as a Target for Kidney Disease Prevention in Diabetes? (2020) (0)
- Manipulation of dietary advanced glycation end-product content influences the progression of non-alcoholic fatty liver disease (NAFLD) (2014) (0)
- The Pathogenic Potential of Different Sized AGE Modified Molecules via RAGE Signalling Pathways (2010) (0)
- The Renin Angiotensin System (2011) (0)
- 795 Are Advanced Glycation End Products Associated with Elevated Filling pressures in Diabetes? (2012) (0)
- GLYCOGEN IN THE DIABETIC KIDNEY: THE HERO OR THE VILLAIN? (2018) (0)
- Impaired Oxygen Metabolism in Diabetic Nephropathy: Advanced Glycation, Hypoxia, and Oxidative Stress (2010) (0)
- Dietary advanced glycation end products as an environmental contributor to type 1 diabetes (2013) (0)
- Erratum: Advanced glycation end product intervention reduce diabetes-accelerated atherosclerosis (Diabetes (2005) 53, (1813-1823)) (2006) (0)
- ROSIGLITAZONE ATTENUATES ATHEROSCLEROSIS IN A MODEL OF INSULIN DEFICIENCY (2004) (0)
- Up front (2017) (0)
- Extracellular Matrix Glycation and Pathogenesis of Diabetic Complications (2010) (0)
- Running title : Heat treated diets and glucose homeostasis Word Count : 5372 Number of Figures : 4 Number of Tables : 1 List of author ’ s names for Pubmed indexing (2011) (0)
- Preface: We are what We Eat (2010) (0)
- Circulating advanced glycation end products and their endogenous secretory receptor are associated with bone turnover markers and with incidence of hip fracture in older men (2018) (0)
- Targeting advanced glycation in obesity related renal dysfunction (2010) (0)
- Interaction between the receptor for advanced glycation end products (RAGE) and estrone (E1) in the development of type 2 diabetic nephropathy (2007) (0)
- Short-term alagebrium chloride (ALT-711) therapy pre-diabetes for the treatment of Type I Diabetes (2015) (0)
- 1P-0273 Attenuation of diabetes-associated atherosclerosis with the advanced glycation end product cross-link breaker, ALT-711 (2003) (0)
- Exploring AGE and sRAGE regulation in response to oral and intravenous glucose loads in individuals with recently diagnosed type 2 diabetes (2019) (0)
- 1P-0156 Accumulation of intestinal cholesterol-rich remnant lipoprotein within arterial vessels may be exacerbated by advanced glycation endproducts and the co-localization of proteoglycans in diabetes (2003) (0)
- Renal Dietitians Symposium – CKD and The Gut (2014) (0)
- In Db/db mice, Sglt2 inhibition does not improve diabetic nephropathy despite glycaemic improvements (2015) (0)
- Heat shock protein expression in early diabetic nephropathy (2007) (0)
- A Novel Mechanism of Mental Illness: Carbonyl Stress Induced Schizophrenia: A Glyoxalase I Deficit Pedigree with Psychosis (2010) (0)
- Oligosaccharyltransferase-48 as a Novel Mediator of Chronic Kidney Disease in Diabetes (2013) (0)
- Glycation in diabetic nephropathy (2010) (0)
- Beneficial Effects of Ramipril Treatment on Diastolic Function, Structural Remodelling and Apoptosis in a Mouse Model of Type 2 Diabetes (2011) (0)
- Serum Low Molecular Weight Fluorescent AGEs are Higher in Neonates than in Adults: Role of Kidney Metabolism (2010) (0)
- The Receptor for Advanced Glycation End Products (RAGE): A Potential Target for Therapeutic Intervention in the Progression of Non-Alcoholic Fatty Liver Disease (NAFLD) (2020) (0)
- INTERACTIONS BETWEEN THE RAS, ADVANCED GLYCATION AND NF-kB IN THE DIABETIC KIDNEY: INTERVENTIONAL STUDIES (2002) (0)
- Interaction between the renin-angiotensin system (RAS) and advanced glycation end products (AGES) in the development of diabetic nephropathy (2008) (0)
- Advanced Glycation Endproducts: Biomarkers for Age-related Macular Degeneration (2010) (0)
- Targeting advanced glycation with pharmaceutical agents: where are we now? (2016) (0)
- Receptor for advanced glycation end products is a regulator or glucagon production (2013) (0)
- The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion in experimental diabetic kidney disease via promotion of endoplasmic reticulum stress (2019) (0)
- Are Advanced Glycation End Products (AGEs) Associated with Elevated Filling Pressures Diabetes (2012) (0)
- Th-P16:287 Rosiglitazone and gemfibrozil mediate lipid and glucose independent anti-atherogenic and renoprotective actions in a model of experimental diabetes (2006) (0)
- Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes (2015) (0)
- Role of Carbonyl/Oxidative Stress on the Pathogenesis of Chronic Kidney Disease and the Metabolic Syndrome (2010) (0)
- Taste Modulating Maillard Reaction Products of Creatinine (2010) (0)
- Glycation: a new hope in targeting hepatocellular carcinoma? (2017) (0)
- SaO035SYNBIOTIC THERAPY IN PRE-DIALYSIS: A RANDOMISED CONTROLLED TRIAL (2015) (0)
- Determining the metabolic impact of dietary carbohydrate composition in the setting of low, medium and high protein diets (2019) (0)
- Diabetes research : The best result for ages (2005) (0)
- Diabetes-induced effects on endothelial function and the actions of nitric oxide (2006) (0)
- Urinary Excretion of Non-toxic and Toxic Carbonyls as Urea Derivatives (2010) (0)
- ADVANCED GLYCATION ENDPRODUCTS AUGMENT HEPATIC FIBROSIS IN AN EXPERIMENTAL MODEL OF CHRONIC LIVER DISEASE (2010) (0)
- Methylglyoxal induced insulin resistance in podocytes contributes to diabetic kidney disease (2013) (0)
- Do extracellular (circulating or dietary) advanced glycation end products mediate mitochondrial dysfunction in the kidney (2005) (0)
- Interactions between the renin angiotensin system and advanced glycation in diabetic nephropathy (2005) (0)
- Advanced glycation end products (AGEs) are cross-sectionally associated with insulin secretion in healthy subjects (2013) (0)
- Glyoxalase-1 Inhibition Leads to Diabetic Kidney Disease Associated with Podocyte Insulin Resistance (2013) (0)
- Metal Catalyzed Lens Crystallin Oxidation During Aging and in Diabetes: The Role of Glutathione (2010) (0)
- Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes (2017) (0)
- Interference with advanced glycation end-products (AGEs) attenuates extracellular matrix (ECM) accumulation in diabetic nephropathy via protein kinase C (PKC) dependent pathways. (2003) (0)
- Plasma Hepatocyte Growth Factor (HGF) Is Inversely Associated with Insulin Sensitivity in Healthy Humans (2009) (0)
- Abstract 14164: Coenzyme Q10 Rescues Diastolic Dysfunction, Cardiomyocyte Hypertrophy and Cardiac Fibrosis in Female db/db Type 2 Diabetic Mice (2010) (0)
- Flux of advanced glycation end products across the kidney as a contributor to renal disease in diabetes (2014) (0)
- Nuclear Expression and DNA Binding Capacity of Receptor for Advanced Glycation End Products in Renal Tissue (2019) (0)
- Inhibitors of advanced glycation end product accumulation ameliorate renal injury in the diabetic apoE knockout mouse (2004) (0)
- Urinary, but not serum levels of the AGE, n-carboxymethyl-lysine are associated with progressive nephropathy in patients with type 1 and type 2 diabetes (2008) (0)
- Ubiquinone Is Renoprotective in An Experimental Model of Type 2 Diabetes (2011) (0)
- IL-22-mediated suppression of islet inflammation (2015) (0)
- Mitochondrial Dysfunction in Individuals with Diabetic Kidney Disease: A Systematic Review (2022) (0)
- Receptor for Advanced Glycation End Products Is a Negative Regulator of Glucagon Production (2014) (0)
- The Maillard Reaction – A Journey from the Discovery of Advanced Glycation Endproducts to their Chief Cellular Receptor, RAGE: A Mechanism Underlying Diabetic Complications and the Inflammatory Response (2010) (0)
- Role of the Glyoxalase System in Renal Senescence (2010) (0)
- Structural Analysis of a Skin Collagen-linked Fluorophore that Increases in Diabetes and End-stage Renal Disease (2010) (0)
- RAGE antagonism with azeliragon improves xenograft rejection by T cells in humanized mice. (2022) (0)
- Understanding Novel Genetic Factors Underlying Circulating Cystatin C and Kidney Function (2016) (0)
- Activation of Cellular Antioxidative Defense Mechanisms by Carboxymethyl-lysine-receptor for Advanced Glycation End-products (RAGE) Interaction (2010) (0)
- The role of GLUT4 in the kidney proximal tubule in blood glucose control and kidney function (2017) (0)
- Modification of Human Serum Albumin with Reactive Aldehydes Alters the Antioxidant Activity (2010) (0)
- Book Chapter The Receptor for Advanced Glycation End Products (RAGE): A Potential Target for Therapeutic Intervention in the Progression of Non-Alcoholic Fatty Liver Disease (NAFLD) (2020) (0)
- Coenzyme Q10 Inhibits Cardiomyocyte Hypertrophy, Myocardial Fibrosis and Diastolic Dysfunction in a Mouse Model of Type 2 Diabetes (2010) (0)
- Deficiency in Apoptosis Inducing Factor Recapitulates Diabetic Nephropathy via Aberrant Mitochondrial Homeostasis (2015) (0)
- Modulation of pancreatic islet oxidative and ER stress with IL-22 to ameliorate metabolic syndrome in obesity (2014) (0)
- 925 ARE ADVANCED GLYCATION END PRODUCTS ASSOCIATED WITH MACROVASCULAR DISEASE IN TYPE 2 DIABETES MELLITUS? (2012) (0)
- Oxidative Stress and the Maillard Reaction in Food (2010) (0)
- Mitochondrial targeting of superoxide by Mitoq improves metabolic renal dysfunction (2014) (0)
- Effect of dietary advanced glycation end products on inflammation and cardiovascular risks in healthy overweight adults: a randomised crossover trial (2017) (0)
- Formation of Mutagens/Carcinogens under Physiological Conditions and the Inhibitory Effects of Daily Foods on their Formation and the Induction of Genotoxicity (2010) (0)
- Isolation of Glucose Ureide, Urea Derivative of Glucose, in Human Urine (2010) (0)
- 965 ELEVATING HDL VIA INHIBITION OF CHOLESTERYL ESTER TRANSFER PROTEIN (CETP) INCREASES CIRCULATING INSULIN, INSULIN SECRETION AND CHOLESTEROL EFFLUX FROM PANCREATIC &bgr;-CELLS (2012) (0)
- Response to Letter to the Editor: "Advanced Glycation End Products and esRAGE Are Associated With Bone Turnover and Incidence of Hip Fracture in Older Men". (2018) (0)
- Therapies which lower advanced glycation end products influence experimental autoimmune diabetes in a time dependent manner (2013) (0)
- Methylglyoxal Modification of Heat-shock Protein 27 in Colon Mucosa of Human Ulcerative Colitis (2010) (0)
- Improved Extraction of Acrylamide and its Quantification in Pork Sausages (2010) (0)
- Diabetic kidney disease: a role for advanced glycation end-product receptor 1 (AGE-R1)? (2016) (0)
- Expression of connective tissue growth factor in the diabetic kidney: association with renal collagen synthesis. (2002) (0)
This paper list is powered by the following services:
Other Resources About Josephine Forbes
What Schools Are Affiliated With Josephine Forbes?
Josephine Forbes is affiliated with the following schools: