Joshua Brickman
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Most Influential Person Now
American / British professor of stem cell and developmental biology
Joshua Brickman's AcademicInfluence.com Rankings
Joshua Brickmanphilosophy Degrees
Philosophy
#12044
World Rank
#16664
Historical Rank
#2333
USA Rank
Logic
#9011
World Rank
#11362
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#1552
USA Rank

Joshua Brickmanbiology Degrees
Biology
#15167
World Rank
#19091
Historical Rank
#2987
USA Rank
Developmental Biology
#223
World Rank
#231
Historical Rank
#36
USA Rank

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Philosophy Biology
Joshua Brickman's Degrees
- Bachelors Biology University of Oxford
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Why Is Joshua Brickman Influential?
(Suggest an Edit or Addition)According to Wikipedia, Joshua Mark Brickman is an American/British biologist. He is a professor of stem cell and developmental biology at the University of Copenhagen. Brickman received a Bachelor of Arts degree in Chemistry and Philosophy from the University of Vermont in 1985 and a PhD in Molecular Cellular Biology from Harvard University in 1996
Joshua Brickman's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse (1998) (714)
- Heterozygous HESX1 mutations associated with isolated congenital pituitary hypoplasia and septo-optic dysplasia. (2001) (305)
- Functional Heterogeneity of Embryonic Stem Cells Revealed through Translational Amplification of an Early Endodermal Transcript (2010) (244)
- Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome (2018) (238)
- An HMG-like protein that can switch a transcriptional activator to a repressor (1994) (232)
- Totipotent Embryonic Stem Cells Arise in Ground-State Culture Conditions (2013) (217)
- Conserved roles for Oct4 homologues in maintaining multipotency during early vertebrate development (2006) (166)
- Targeted Mutagenesis of the Hira Gene Results in Gastrulation Defects and Patterning Abnormalities of Mesoendodermal Derivatives Prior to Early Embryonic Lethality (2002) (145)
- Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders. (2001) (131)
- Anterior definitive endoderm from ESCs reveals a role for FGF signaling. (2008) (125)
- A homozygous mutation in HESX1 is associated with evolving hypopituitarism due to impaired repressor-corepressor interaction. (2003) (122)
- Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function. (2000) (107)
- Gene expression heterogeneities in embryonic stem cell populations: origin and function. (2011) (101)
- Erk signaling suppresses embryonic stem cell self-renewal to specify endoderm. (2014) (86)
- New eukaryotic transcriptional repressers (1993) (79)
- Interactions between an HMG-1 protein and members of the Rel family. (1999) (78)
- Naïve human pluripotent stem cells respond to Wnt, Nodal and LIF signalling to produce expandable naïve extra-embryonic endoderm (2019) (78)
- Transcriptional Activation by Oct4 Is Sufficient for the Maintenance and Induction of Pluripotency (2012) (71)
- Properties of embryoid bodies (2017) (62)
- HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development (2018) (60)
- Hex acts with β-catenin to regulate anteroposterior patterning via a Groucho-related co-repressor and Nodal (2006) (55)
- Embryonic Stem Cell Culture Conditions Support Distinct States Associated with Different Developmental Stages and Potency (2016) (55)
- Dynamic lineage priming is driven via direct enhancer regulation by ERK (2019) (54)
- Insulin fine-tunes self-renewal pathways governing naive pluripotency and extra-embryonic endoderm (2017) (52)
- LIF supports primitive endoderm expansion during pre-implantation development (2015) (50)
- Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release. (2021) (50)
- Interactions of a Rel protein with its inhibitor. (1995) (49)
- FGF signalling as a mediator of lineage transitions—Evidence from embryonic stem cell differentiation (2010) (49)
- Modulating the potency of an activator in a yeast in vitro transcription system (1994) (47)
- A Conserved Oct4/POUV-Dependent Network Links Adhesion and Migration to Progenitor Maintenance (2013) (45)
- Four simple rules that are sufficient to generate the mammalian blastocyst (2017) (42)
- Axis duplication and anterior identity in the mouse embryo. (1997) (42)
- Pluripotency and tumorigenicity (2002) (42)
- Investigation of microsphere-mediated cellular delivery by chemical, microscopic and gene expression analysis. (2010) (40)
- HOXB4 Can Enhance the Differentiation of Embryonic Stem Cells by Modulating the Hematopoietic Niche (2012) (37)
- Inhibition of Cortical Neuron Differentiation by Groucho/TLE1 Requires Interaction with WRPW, but Not Eh1, Repressor Peptides* (2008) (35)
- Molecular Genetics of Septo-Optic Dysplasia (2000) (33)
- The molecular underpinnings of totipotency (2014) (33)
- PI3K/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix (2013) (32)
- The POU-er of gene nomenclature (2014) (31)
- From pluripotency to totipotency: an experimentalist's guide to cellular potency (2020) (29)
- Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection. (2003) (27)
- Microsphere‐Mediated Protein Delivery into Cells (2009) (26)
- Polycomb enables primitive endoderm lineage priming in embryonic stem cells (2016) (25)
- Gro/TLE enables embryonic stem cell differentiation by repressing pluripotent gene expression. (2015) (24)
- Microsphere-based tracing and molecular delivery in embryonic stem cells. (2009) (22)
- Microspheres as a vehicle for biomolecule delivery to neural stem cells. (2009) (16)
- Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells (2009) (15)
- Differentiation of embryonic stem cells into anterior definitive endoderm. (2009) (13)
- A novel triple fusion reporter system for use in gene trap mutagenesis (2007) (12)
- Transcriptional regulation of Hhex in hematopoiesis and hematopoietic stem cell ontogeny. (2017) (11)
- METHODS IN ENZYMOLOGY, VOL 477: GUIDE TO TECHNIQUES IN MOUSE DEVELOPMENT, PART B: MOUSE MOLECULAR GENETICS, SECOND EDITION (2010) (11)
- A wider context for gene trap mutagenesis. (2010) (9)
- PI 3 K / Akt 1 signalling specifies foregut precursors by generating regionalized extracellular matrix (2013) (8)
- Oct4: the final frontier, differentiation defining pluripotency. (2013) (7)
- Identification of the central intermediate in the extra-embryonic to embryonic endoderm transition through single-cell transcriptomics (2022) (6)
- Explorer Conserved roles for Oct 4 homologues in maintaining multipotency during early vertebrate development (2017) (5)
- Long-term feeder-free culture of human pancreatic progenitors on fibronectin or matrix-free polymer potentiates β cell differentiation (2022) (5)
- Evolutionary origin of vertebrate OCT4/POU5 functions in supporting pluripotency (2022) (3)
- Transcriptional heterogeneity and cell cycle regulation as central determinants of Primitive Endoderm priming (2022) (3)
- Genetic Deletion of Hesx1 Promotes Exit from the Pluripotent State and Impairs Developmental Diapause (2019) (3)
- Differentiation of Mouse Embryonic Stem Cells into Ventral Foregut Precursors. (2016) (3)
- An automated microfluidic device for time-lapse imaging of mouse embryonic stem cells. (2019) (2)
- Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development (2021) (2)
- Can a Cell Put Its Arms around a Memory? (2020) (2)
- Physical properties and actin organization in embryonic stem cells depend on differentiation stage (2020) (1)
- Surveillance for Secure Differentiation. (2017) (1)
- Changes in Cell Morphology and Actin Organization in Embryonic Stem Cells Cultured under Different Conditions (2021) (1)
- Expansion of Ventral Foregut Primes the Enhancer Landscape for Organ Specific Differentiation (2022) (1)
- Survival of the fattest (2013) (1)
- Expansion of ventral foregut is linked to changes in the enhancer landscape for organ-specific differentiation (2023) (0)
- Functional analysis of novel heterozygous mutations in HESX1 (2002) (0)
- 17-P033 Gene trap vectors for unbiased and expression-independent mutagenesis in embryonic stem cells (2009) (0)
- Mutations within HESX1 in CPHD/IGHD are associated with impaired repression due to compromised interaction with the Groucho co-repressor (2003) (0)
- The people behind the papers – Madeleine Linneberg-Agerholm, Yan Fung Wong and Josh Brickman (2019) (0)
- , Adam Repressor Peptides Interaction with WRPW , but Not Eh 1 , RequiresDifferentiation by Groucho / TLE 1 Inhibition of Cortical Neuron Developmental Biology : Molecular Basis of Cell (2017) (0)
- 14-P003 Identification of genes expressed in the anterior definitive endoderm (2009) (0)
- Transcription Factor Co-Expression Mediates Lineage Priming for Embryonic and Extra-Embryonic Differentiation (2023) (0)
- Optical quantification of forces at play during stem cell differentiation (2016) (0)
- Determinants of Primitive Endoderm Priming (0)
- Edinburgh Research Explorer Expression-independent gene trap vectors for random and targeted mutagenesis in embryonic stem cells (2017) (0)
- The N-terminus of the transcriptional repressor HESX1 facilitates interaction with the homeodomain activator PROP1 (2004) (0)
- A novel mutation within the conserved eh-1 domain of HESX1 causes evolving CPHD due to the loss of interaction with the co-repressor TLE1 (2003) (0)
- 17-P037 A role for Grg/TLE proteins in the control of mouse ES cell self renewal and differentiation (2009) (0)
- 18-P007 Identification of evolutionarily conserved targets of the Oct4 transcription factor (2009) (0)
- 17-P035 Functional heterogeneity of murine embryonic stem cells revealed through translational amplification in an early endoderm marker (2009) (0)
- Differentiation and Expansion of Human Extra-Embryonic Endoderm Cell Lines from Naïve Pluripotent Stem Cells. (2021) (0)
- Experimental single molecule fluorescence microscopy for investigation of embryonic stem cell priming and transcription regulation (2019) (0)
- Erratum to: Resolving Heterogeneity: Fluorescence-Activated Cell Sorting of Dynamic Cell Populations from Feeder-Free Mouse Embryonic Stem Cell Culture. (2016) (0)
- Editor's evaluation: The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates (2021) (0)
- ORGN 220-Synthesis of chemically robust and functionalized polymer-quantum dot microspheres (2007) (0)
- HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development (2018) (0)
- From pluripotency to differentiation : laying the foundations for the body pattern in the mouse embryo ’ . Subject Areas : developmental biology (2014) (0)
- Investigation of microsphere-mediated cellular delivery (2010) (0)
- 14-P024 Physiologic and defined directed differentiation of human embryonic stem cells and human endodermal cultures to hepatocytes (2009) (0)
- 14-P008 Mechanisms of HOXB4 mediated haematopoietic differentiation in mouse ES cells (2009) (0)
- A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation (2022) (0)
- Erratum (2006) (0)
- Author response: PI3K/Akt1 signalling specifies foregut precursors by generating regionalized extra-cellular matrix (2013) (0)
- Dynamic lineage priming is driven via direct enhancer regulation by ERK (2019) (0)
- Author response: Polycomb enables primitive endoderm lineage priming in embryonic stem cells (2016) (0)
- Differential elasticity in lineage segregation of embryonic stem cells (2022) (0)
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