Juan Carlos Izpisua Belmonte
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Spanish biochemist
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Juan Carlos Izpisua Belmontebiology Degrees
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#1172
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#1999
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Biotechnology
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#17
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Developmental Biology
#56
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#60
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Genetics
#284
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#336
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Biology
Juan Carlos Izpisua Belmonte's Degrees
- PhD Biochemistry University of Valencia
Why Is Juan Carlos Izpisua Belmonte Influential?
(Suggest an Edit or Addition)According to Wikipedia, Juan Carlos Izpisua Belmonte is a Spanish biochemist and developmental biologist. He is a professor in the Gene Expression Laboratories at the Salk Institute for Biological Studies in La Jolla, California since 1993.
Juan Carlos Izpisua Belmonte's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Efficient and rapid generation of induced pluripotent stem cells from human keratinocytes (2008) (1429)
- Somatic coding mutations in human induced pluripotent stem cells (2011) (1218)
- Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation (2010) (1172)
- Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture. (2011) (858)
- In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration (2016) (804)
- Disease-corrected haematopoietic progenitors from Fanconi anaemia induced pluripotent stem cells (2009) (698)
- Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse. (2001) (676)
- Dedifferentiation, transdifferentiation and reprogramming: three routes to regeneration (2011) (587)
- Linking the p53 tumor suppressor pathway to somatic cell reprogramming (2009) (584)
- Pitx2 determines left–right asymmetry of internal organs in vertebrates (1998) (530)
- In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming (2016) (494)
- The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming (2011) (473)
- Methods for making induced pluripotent stem cells: reprogramming à la carte (2011) (456)
- Mechanism of Nodal Flow: A Conserved Symmetry Breaking Event in Left-Right Axis Determination (2005) (456)
- Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud. (1998) (435)
- Generation of induced pluripotent stem cells from human cord blood using OCT4 and SOX2. (2009) (418)
- Patterning mechanisms controlling vertebrate limb development. (2001) (417)
- WNT Signals Control FGF-Dependent Limb Initiation and AER Induction in the Chick Embryo (2001) (370)
- A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging (2015) (358)
- Recapitulation of premature aging with iPSCs from Hutchinson-Gilford progeria syndrome (2011) (357)
- Mitochondrial regulation in pluripotent stem cells. (2013) (338)
- Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin. (1999) (335)
- Mechanisms of Left–Right Determination in Vertebrates (2000) (332)
- Progressive degeneration of human neural stem cells caused by pathogenic LRRK2 (2012) (324)
- Directed differentiation of human pluripotent cells to ureteric bud kidney progenitor-like cells (2013) (322)
- Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency (2017) (320)
- LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells (2011) (310)
- In Vivo Target Gene Activation via CRISPR/Cas9-Mediated Trans-epigenetic Modulation (2017) (309)
- Epicardial retinoid X receptor is required for myocardial growth and coronary artery formation (2005) (302)
- Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells (2015) (294)
- A High Proliferation Rate Is Required for Cell Reprogramming and Maintenance of Human Embryonic Stem Cell Identity (2011) (290)
- The Forkhead protein, FoxJ1, specifies node-like cilia in Xenopus and Zebrafish embryos (2008) (288)
- The T-box genes Tbx4 and Tbx5 regulate limb outgrowth and identity (1999) (286)
- Retinoic acid signalling links left–right asymmetric patterning and bilaterally symmetric somitogenesis in the zebrafish embryo (2005) (283)
- Nanog binds to Smad1 and blocks bone morphogenetic protein-induced differentiation of embryonic stem cells (2006) (276)
- Interspecies Chimerism with Mammalian Pluripotent Stem Cells (2017) (275)
- Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1. (1999) (275)
- Generation of mouse-induced pluripotent stem cells by transient expression of a single nonviral polycistronic vector (2009) (272)
- Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells (2010) (267)
- MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb (2003) (263)
- Wnt/β-catenin signaling regulates vertebrate limb regeneration (2006) (254)
- Notch activity acts as a sensor for extracellular calcium during vertebrate left–right determination (2004) (253)
- Waves of early transcriptional activation and pluripotency program initiation during human preimplantation development (2011) (244)
- A new method for detection and quantification of heartbeat parameters in Drosophila, zebrafish, and embryonic mouse hearts. (2009) (242)
- The novel Cer-like protein Caronte mediates the establishment of embryonic left–right asymmetry (1999) (232)
- Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations (2016) (228)
- Epicardial retinoid X receptor alpha is required for myocardial growth and coronary artery formation. (2005) (228)
- Selective Elimination of Mitochondrial Mutations in the Germline by Genome Editing (2015) (225)
- Targeted gene correction of laminopathy-associated LMNA mutations in patient-specific iPSCs. (2011) (224)
- Left–right asymmetry in the vertebrate embryo: from early information to higher-level integration (2006) (223)
- Role of Rel/NF-κB transcription factors during the outgrowth of the vertebrate limb (1998) (221)
- Concise Review: Induced Pluripotent Stem Cells Versus Embryonic Stem Cells: Close Enough or Yet Too Far Apart? (2012) (215)
- An alternative pluripotent state confers interspecies chimaeric competency (2015) (213)
- Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb (1997) (209)
- Diseases in a dish: modeling human genetic disorders using induced pluripotent cells (2011) (202)
- The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10. (2002) (198)
- Brains, Genes, and Primates (2015) (194)
- The ageing epigenome and its rejuvenation (2020) (194)
- Single-Cell Transcriptomic Atlas of Primate Ovarian Aging (2020) (190)
- Identification of Novel Long Noncoding RNAs Underlying Vertebrate Cardiovascular Development (2015) (185)
- In vivo activation of a conserved microRNA program induces mammalian heart regeneration. (2014) (183)
- Notch activity induces Nodal expression and mediates the establishment of left-right asymmetry in vertebrate embryos. (2003) (182)
- Noncanonical Wnt signaling regulates midline convergence of organ primordia during zebrafish development. (2005) (179)
- Complete Meiosis from Human Induced Pluripotent Stem Cells (2011) (178)
- Dorsal cell fate specified by chick Lmx1 during vertebrate limb development (1996) (175)
- Human and mouse adipose-derived cells support feeder-independent induction of pluripotent stem cells (2010) (175)
- Albumin-Associated Lipids Regulate Human Embryonic Stem Cell Self-Renewal (2008) (171)
- Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones. (2014) (168)
- Transcriptionally Active HERV-H Retrotransposons Demarcate Topologically Associating Domains in Human Pluripotent Stem Cells (2019) (166)
- Forty years of IVF. (2018) (165)
- Wnt/beta-catenin signaling regulates vertebrate limb regeneration. (2006) (164)
- Asymmetric nodal signaling in the zebrafish diencephalon positions the pineal organ. (2000) (163)
- Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways (2009) (161)
- Fine tuning the extracellular environment accelerates the derivation of kidney organoids from human pluripotent stem cells (2019) (160)
- Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network. (2019) (158)
- Transcriptional coactivator PGC-1alpha regulates chondrogenesis via association with Sox9. (2005) (157)
- Metabolic rescue in pluripotent cells from patients with mtDNA disease (2015) (157)
- Regulation of Stem Cell Aging by Metabolism and Epigenetics. (2017) (157)
- Beyond early development: Xenopus as an emerging model for the study of regenerative mechanisms (2009) (156)
- RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex (1999) (156)
- Sp8 and Sp9, two closely related buttonhead-like transcription factors, regulate Fgf8 expression and limb outgrowth in vertebrate embryos (2004) (154)
- Identification of a specific reprogramming-associated epigenetic signature in human induced pluripotent stem cells (2012) (149)
- Characterization of pluripotent stem cells (2013) (149)
- Caloric Restriction Reprograms the Single-Cell Transcriptional Landscape of Rattus Norvegicus Aging (2020) (147)
- Reprogramming of human fibroblasts to pluripotency with lineage specifiers. (2013) (146)
- The role of TGFβs and Sox9 during limb chondrogenesis (2006) (146)
- Efficient derivation of stable primed pluripotent embryonic stem cells from bovine blastocysts (2018) (141)
- A functional genomics approach to the mode of action of apratoxin A (2006) (140)
- A human circulating immune cell landscape in aging and COVID-19 (2020) (137)
- 3D Culture Supports Long-Term Expansion of Mouse and Human Nephrogenic Progenitors. (2016) (135)
- Embryonic stem cell-like cells derived from adult human testis. (2010) (134)
- A Cut above the Rest: Targeted Genome Editing Technologies in Human Pluripotent Stem Cells* (2013) (133)
- Sp8 exhibits reciprocal induction with Fgf8 but has an opposing effect on anterior-posterior cortical area patterning (2007) (131)
- Regulation of primary cilia formation and left-right patterning in zebrafish by a noncanonical Wnt signaling mediator, duboraya (2006) (131)
- Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression (2008) (130)
- Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures (2019) (130)
- Dynamic Pluripotent Stem Cell States and Their Applications. (2015) (129)
- Autophagic control of cell ‘stemness’ (2013) (128)
- Stem cells and interspecies chimaeras (2016) (126)
- Hypoxia Induces Myocardial Regeneration in Zebrafish (2012) (123)
- PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype (2015) (122)
- Efficient generation of A9 midbrain dopaminergic neurons by lentiviral delivery of LMX1A in human embryonic stem cells and induced pluripotent stem cells. (2012) (120)
- Navigating the epigenetic landscape of pluripotent stem cells (2012) (119)
- A histone demethylase is necessary for regeneration in zebrafish (2009) (119)
- The limb field mesoderm determines initial limb bud anteroposterior asymmetry and budding independent of sonic hedgehog or apical ectodermal gene expressions. (1996) (118)
- Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. (2012) (117)
- Human progenitor cells derived from cardiac adipose tissue ameliorate myocardial infarction in rodents. (2010) (116)
- The direction of gut looping is established by changes in the extracellular matrix and in cell:cell adhesion (2008) (115)
- Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs (2014) (113)
- Cellular Metabolism and Induced Pluripotency (2016) (111)
- Mesenchyme with fgf-10 expression is responsible for regenerative capacity in Xenopus limb buds. (2000) (111)
- Ground rules of the pluripotency gene regulatory network (2017) (109)
- Dissecting primate early post-implantation development using long-term in vitro embryo culture (2019) (106)
- MicroRNAs in embryonic stem cell function and fate. (2010) (106)
- The role of Alx-4 in the establishment of anteroposterior polarity during vertebrate limb development. (1998) (105)
- Lineage conversion methodologies meet the reprogramming toolbox (2012) (104)
- Epigenetic mechanisms that regulate cell identity. (2010) (104)
- Generation of induced pluripotent stem cells from human cord blood cells with only two factors: Oct4 and Sox2 (2010) (103)
- Histone H1 Variants Are Differentially Expressed and Incorporated into Chromatin during Differentiation and Reprogramming to Pluripotency* (2011) (102)
- BMP-3 and BMP-6 structures illuminate the nature of binding specificity with receptors. (2007) (102)
- Induced pluripotent stem cells and reprogramming: seeing the science through the hype (2009) (102)
- Hypoxia Drives Breast Tumor Malignancy through a TET-TNFα-p38-MAPK Signaling Axis. (2015) (100)
- Regeneration and reprogramming compared (2010) (99)
- Reprogramming of Human Fibroblasts to Induced Pluripotent Stem Cells under Xeno‐free Conditions (2009) (99)
- Tbx2 and Tbx3 Regulate the Dynamics of Cell Proliferation during Heart Remodeling (2007) (95)
- Single-Dose CRISPR/Cas9 Therapy Extends Lifespan of Mice with Hutchinson-Gilford Progeria Syndrome (2018) (93)
- CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs (2017) (93)
- Generation of Pig iPS Cells: A Model for Cell Therapy (2011) (92)
- Development and Validation of an Automated High-Throughput System for Zebrafish In Vivo Screenings (2012) (91)
- In vivo reprogramming of wound-resident cells generates skin epithelial tissue (2018) (90)
- The role of TGFbetas and Sox9 during limb chondrogenesis. (2006) (89)
- BMP-2/6 Heterodimer Is More Effective than BMP-2 or BMP-6 Homodimers as Inductor of Differentiation of Human Embryonic Stem Cells (2010) (86)
- The generation of kidney organoids by differentiation of human pluripotent cells to ureteric bud progenitor–like cells (2014) (86)
- Compensatory growth mechanisms regulated by BMP and FGF signaling mediate liver regeneration in zebrafish after partial hepatectomy (2009) (83)
- Brief Report: Efficient Generation of Hematopoietic Precursors and Progenitors from Human Pluripotent Stem Cell Lines (2011) (83)
- Organoids - Preclinical Models of Human Disease. (2019) (83)
- A Single-Cell Transcriptomic Atlas of Human Skin Aging. (2020) (81)
- p53: Guardian of reprogramming (2010) (80)
- miR25/93 mediates hypoxia-induced immunosuppression by repressing cGAS (2017) (80)
- Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1. (2010) (79)
- Conversion of human fibroblasts into angioblast-like multipotent progenitor cells (2012) (79)
- iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types (2017) (78)
- In vivo genome editing via the HITI method as a tool for gene therapy (2018) (78)
- Neuronopathic Gaucher's disease: induced pluripotent stem cells for disease modelling and testing chaperone activity of small compounds. (2013) (78)
- Stem Cells: A Renaissance in Human Biology Research (2016) (77)
- Maintenance of embryonic stem cell pluripotency by Nanog-mediated reversal of mesoderm specification (2006) (76)
- Creating Patient-Specific Neural Cells for the In Vitro Study of Brain Disorders (2015) (76)
- Reprogramming with defined factors: from induced pluripotency to induced transdifferentiation. (2010) (76)
- Lhx2, a vertebrate homologue of apterous, regulates vertebrate limb outgrowth. (1998) (74)
- Dedifferentiation, Transdifferentiation, and Reprogramming: Future Directions in Regenerative Medicine (2013) (73)
- Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis (2019) (73)
- Brief Report: Oxidative Stress Mediates Cardiomyocyte Apoptosis in a Human Model of Danon Disease and Heart Failure (2015) (71)
- Reprogramming toward heart regeneration: stem cells and beyond. (2013) (69)
- Simple Generation of Human Induced Pluripotent Stem Cells Using Poly-β-amino Esters As the Non-viral Gene Delivery System* (2011) (69)
- Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc (2012) (67)
- Differential expression of Tbx4 and Tbx5 in Zebrafish Fin buds (1999) (67)
- Deconstructing the pluripotency gene regulatory network (2018) (66)
- Sall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activities (2009) (66)
- ErbB2 and ErbB3 regulate amputation-induced proliferation and migration during vertebrate regeneration. (2009) (65)
- Analysis of protein coding mutations in hiPSCs and their possible role during somatic cell reprogramming (2013) (64)
- Limbs are moving: where are they going? (1998) (64)
- iPSCs: induced back to controversy. (2011) (64)
- Generation of Feeder-Free Pig Induced Pluripotent Stem Cells without Pou5f1 (2012) (63)
- Macrohistone variants preserve cell identity by preventing the gain of H3K4me2 during reprogramming to pluripotency. (2013) (63)
- Isolation and in vitro culture of primary cardiomyocytes from adult zebrafish hearts (2013) (63)
- Wnt signaling and PKA control Nodal expression and left-right determination in the chick embryo. (2001) (62)
- Bone morphogenetic protein-2 and -6 heterodimer illustrates the nature of ligand-receptor assembly. (2010) (62)
- Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells (2019) (61)
- Direct conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factors (2013) (61)
- Generation of Induced Pluripotent Stem Cells from Human Renal Proximal Tubular Cells with Only Two Transcription Factors, Oct4 and Sox2* (2012) (59)
- Loss of MAX results in meiotic entry in mouse embryonic and germline stem cells (2016) (59)
- Theoretical and experimental approaches to understand morphogen gradients (2008) (59)
- Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs (2011) (58)
- Transcriptomics approach to investigate zebrafish heart regeneration (2010) (58)
- Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo (2021) (58)
- Single-cell transcriptomic atlas of primate cardiopulmonary aging (2020) (58)
- Pitx2 regulates gonad morphogenesis (2008) (57)
- A protocol describing the genetic correction of somatic human cells and subsequent generation of iPS cells (2010) (57)
- Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis (2019) (56)
- Anti-Aging Strategies Based on Cellular Reprogramming. (2016) (56)
- New strategies in kidney regeneration and tissue engineering (2014) (55)
- iPSC technology to study human aging and aging-related disorders. (2012) (55)
- Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency (2012) (55)
- Analysis of Human and Mouse Reprogramming of Somatic Cells to Induced Pluripotent Stem Cells. What Is in the Plate? (2010) (54)
- Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy (2012) (53)
- FOXO3-Engineered Human ESC-Derived Vascular Cells Promote Vascular Protection and Regeneration. (2019) (53)
- Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts. (2016) (53)
- miles-apart-Mediated regulation of cell–fibronectin interaction and myocardial migration in zebrafish (2007) (52)
- Establishment of human iPSC-based models for the study and targeting of glioma initiating cells (2016) (51)
- Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells (2017) (51)
- Generation of cardiomyocytes from new human embryonic stem cell lines derived from poor-quality blastocysts. (2008) (51)
- Evidence that members of the Cut/Cux/CDP family may be involved in AER positioning and polarizing activity during chick limb development. (2000) (51)
- The cell cycle inhibitor p27Kip1 controls self-renewal and pluripotency of human embryonic stem cells by regulating the cell cycle, Brachyury and Twist (2011) (50)
- Post-translational modulation of pluripotency. (2012) (50)
- Switching cell fate, ncRNAs coming to play (2013) (48)
- Islet1-mediated activation of the β-catenin pathway is necessary for hindlimb initiation in mice (2011) (48)
- A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence (2021) (48)
- Evidence that Shh cooperates with a retinoic acid inducible co-factor to establish ZPA-like activity. (1996) (48)
- iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types. (2017) (47)
- Sequential transfer of left-right information during vertebrate embryo development. (2004) (46)
- Tbx 3 controls the fate of hepatic progenitor cells in liver development by suppressing p 19 ARF expression (45)
- Identification of phosphorylase kinase as a novel therapeutic target through high-throughput screening for anti-angiogenesis compounds in zebrafish (2012) (45)
- Rapid and Highly Efficient Generation of Induced Pluripotent Stem Cells from Human Umbilical Vein Endothelial Cells (2011) (44)
- Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome (2018) (44)
- Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction (2019) (43)
- Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration (2020) (43)
- Skeletal muscle regeneration in Xenopus tadpoles and zebrafish larvae (2012) (42)
- Single-cell omics in ageing: a young and growing field (2020) (42)
- Conversion of Human Fibroblasts Into Monocyte‐Like Progenitor Cells (2014) (41)
- In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice (2022) (38)
- Macro Histone Variants Are Critical for the Differentiation of Human Pluripotent Cells* (2013) (38)
- Study of pluripotency markers in zebrafish embryos and transient embryonic stem cell cultures. (2011) (38)
- Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding (2017) (37)
- Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells (2019) (37)
- Unveiling the establishment of left–right asymmetry in the chick embryo (2004) (37)
- Mathematical approaches to modeling development and reprogramming (2014) (37)
- Bioelectricity and epimorphic regeneration. (2007) (37)
- Molecular basis of left-right asymmetry. (1999) (36)
- Chemically induced pluripotent stem cells (CiPSCs): a transgene-free approach. (2013) (36)
- CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs (2017) (36)
- Establishment of hepatic and neural differentiation platforms of Wilson’s disease specific induced pluripotent stem cells (2012) (36)
- Characterization of dermacan, a novel zebrafish lectican gene, expressed in dermal bones (2004) (35)
- MicroRNAs Contribute to Induced Pluripotent Stem Cell Somatic Donor Memory* (2013) (35)
- Coordinated histone modifications and chromatin reorganization in a single cell revealed by FRET biosensors (2018) (35)
- Regenerating the epigenome (2011) (34)
- Looking to the future following 10 years of induced pluripotent stem cell technologies (2016) (33)
- Characterization of the Epigenetic Changes During Human Gonadal Primordial Germ Cells Reprogramming (2016) (33)
- Regenerative strategies for kidney engineering (2016) (33)
- Systems biology analysis reveals role of MDM2 in diabetic nephropathy. (2016) (32)
- Establishing a Left‐Right Axis in the Embryo (2000) (32)
- Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming. (2020) (32)
- Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs (2016) (31)
- SMYD2 is induced during cell differentiation and participates in early development. (2013) (31)
- In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche (2021) (30)
- An overview of mammalian pluripotency (2016) (30)
- Expression of Fgf19 in the developing chick eye. (2005) (30)
- N-acetylcysteine protects induced pluripotent stem cells from in vitro stress: impact on differentiation outcome. (2012) (29)
- Perspectives on Directions and Priorities for Future Preclinical Studies in Regenerative Medicine (2019) (29)
- Roadblocks in the Path of iPSC to the Clinic (2018) (29)
- Cell cycle gene-specific control of transcription has a critical role in proliferation of primordial germ cells. (2012) (29)
- Anaerobicizing into pluripotency. (2011) (28)
- Retinoic acid regulation of the Mesp-Ripply feedback loop during vertebrate segmental patterning. (2008) (28)
- Aberrant DNA Methylation in Human iPSCs Associates with MYC-Binding Motifs in a Clone-Specific Manner Independent of Genetics. (2017) (28)
- Stem cells: Surf the waves of reprogramming (2013) (28)
- Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis (2012) (27)
- A single-cell transcriptomic atlas of primate pancreatic islet aging (2020) (27)
- Cell fate conversion by mRNA (2011) (27)
- Activin A/BMP2 chimera AB235 drives efficient redifferentiation of long term cultured autologous chondrocytes (2015) (27)
- Cell lineage transport: a mechanism for molecular gradient formation (2006) (26)
- Olfactory stem cells reveal MOCOS as a new player in autism spectrum disorders (2015) (26)
- Single-nucleus transcriptomic landscape of primate hippocampal aging (2021) (26)
- Resurrection of endogenous retroviruses during aging reinforces senescence (2021) (25)
- Roles for noncoding RNAs in cell-fate determination and regeneration (2015) (25)
- Shh, HoxD, Bmp-2, and Fgf-4 gene expression during development of the polydactylous talpid2, diplopodia1, and diplopodia4 mutant chick limb buds. (1996) (25)
- The microenvironment and resistance to personalized cancer therapy (2013) (25)
- Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes (2014) (25)
- Perspectives on the evolutionary origin of tetrapod limbs. (2000) (24)
- Cell surface GRP78 promotes stemness in normal and neoplastic cells (2020) (24)
- Spatially and temporally-restricted expression of two T-box genes during zebrafish embryogenesis (1999) (24)
- Activin/BMP2 chimeric ligands direct adipose-derived stem cells to chondrogenic differentiation. (2013) (24)
- Regenerative medicine: Transdifferentiation in vivo (2013) (24)
- Knowing left from right: the molecular basis of laterality defects. (2000) (23)
- Induced neural stem cells: a new tool for studying neural development and neurological disorders (2012) (23)
- Mending a Faltering Heart. (2016) (22)
- Generation of human organs in pigs via interspecies blastocyst complementation. (2016) (22)
- A Novel Suppressive Effect of Alcohol Dehydrogenase 5 in Neuronal Differentiation* (2014) (22)
- LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death. (2017) (21)
- Modelling long QT syndrome with iPS cells: be still, my beating heart ... (2011) (21)
- Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor (2022) (21)
- Rejuvenating liver and pancreas through cell transdifferentiation (2012) (20)
- DNA Hypermethylation in Somatic Cells Correlates with Higher Reprogramming Efficiency (2012) (20)
- Gating pluripotency via nuclear pores. (2014) (20)
- Development of the limb neuromuscular system. (2001) (20)
- Induced pluripotent stem cell‐based modeling of mutant LRRK2‐associated Parkinson's disease (2019) (20)
- Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues. (2022) (20)
- Polycomb complex recruitment in pluripotent stem cells (2013) (19)
- MiR-23~27~24–mediated control of humoral immunity reveals a TOX-driven regulatory circuit in follicular helper T cell differentiation (2019) (18)
- No factor left behind: generation of transgene-free induced pluripotent stem cells. (2012) (18)
- Brains, Genes, and Primates (2015) (18)
- Human Embryo Editing: Opportunities and Importance of Transnational Cooperation. (2017) (17)
- Efficient Delivery and Functional Expression of Transfected Modified mRNA in Human Embryonic Stem Cell-derived Retinal Pigmented Epithelial Cells (2015) (17)
- M-cadherin-mediated intercellular interactions activate satellite cell division (2013) (17)
- Design Approaches for Generating Organ Constructs. (2019) (17)
- A prevalent neglect of environmental control in mammalian cell culture calls for best practices (2021) (17)
- Metabolic exit from naive pluripotency (2015) (17)
- Molecular Cloning and Developmental Expression of a Hyaluronan and Proteoglycan Link Protein Gene, crtl1/hapln1, in Zebrafish (2008) (17)
- Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis (2021) (17)
- Generation of a Drug-inducible Reporter System to Study Cell Reprogramming in Human Cells* (2012) (16)
- Modeling epigenetic modifications in renal development and disease with organoids and genome editing (2018) (16)
- A widely adaptable approach to generate integration-free iPSCs from non-invasively acquired human somatic cells (2014) (16)
- Insights into the establishment of left-right asymmetries in vertebrates. (2008) (16)
- Understanding the molecular mechanisms of reprogramming. (2016) (15)
- Concealing cellular defects in pluripotent stem cells. (2013) (15)
- Interspecies chimeric complementation for the generation of functional human tissues and organs in large animal hosts (2016) (15)
- Transgenerational inheritance of acquired epigenetic signatures at CpG islands in mice (2023) (15)
- Destabilizing heterochromatin by APOE mediates senescence (2022) (14)
- BMAL1 moonlighting as a gatekeeper for LINE1 repression and cellular senescence in primates (2022) (14)
- Oncofetal gene SALL4 in aggressive hepatocellular carcinoma. (2013) (14)
- Direct reprogramming of porcine fibroblasts to neural progenitor cells (2014) (14)
- Stem cells: A designer's guide to pluripotency (2014) (14)
- iPS cells forgive but do not forget (2011) (14)
- Expression of the chick vascular endothelial growth factor D gene during limb development (2002) (14)
- Transient downregulation of Bmp signalling induces extra limbs in vertebrates (2012) (14)
- Induced pluripotent stem cells in clinical hematology: potentials, progress, and remaining obstacles (2012) (14)
- Derivation of sheep embryonic stem cells under optimized conditions. (2020) (13)
- NFIX – one gene, two knockouts, multiple effects (2008) (13)
- Muscle development during vertebrate limb outgrowth (1999) (13)
- In vivo partial cellular reprogramming enhances liver plasticity and regeneration (2022) (13)
- In vitro generation of platelets through direct conversion: first report in My Knowledge (iMK) (2012) (13)
- Designer Nodal/BMP2 Chimeras Mimic Nodal Signaling, Promote Chondrogenesis, and Reveal a BMP2-like Structure (2013) (13)
- Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis (2018) (12)
- The lysine-specific demethylase 1 is a novel substrate of protein kinase CK2. (2014) (12)
- FOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocardial infarction (2020) (12)
- Holding your breath for longevity (2015) (12)
- Functional Compensation Between Myc and PI3K Signaling Supports Self‐Renewal of Embryonic Stem Cells (2015) (12)
- Mitochondrial dynamics and metabolism in induced pluripotency (2020) (12)
- A protocol to assess cell cycle and apoptosis in human and mouse pluripotent cells (2011) (12)
- Left–right axis determination (2009) (12)
- Chemical combinations potentiate human pluripotent stem cell-derived 3D pancreatic progenitor clusters toward functional β cells (2021) (12)
- Ageing: Genetic rejuvenation of old muscle (2014) (11)
- Accumulation of instability in serial differentiation and reprogramming of parthenogenetic human cells. (2012) (11)
- Cre-LoxP-regulated expression of monoclonal antibodies driven by an ovalbumin promoter in primary oviduct cells (2011) (11)
- Turning human epidermis into pancreatic endoderm. (2010) (11)
- Analysis of transcription factors expressed at the anterior mouse limb bud (2017) (11)
- Cut and Paste: restoring cellular function by gene correction (2011) (11)
- Regenerative medicine: targeted genome editing in vivo (2015) (11)
- Understanding the genetics behind complex human disease with large-scale iPSC collections (2017) (10)
- Author Correction: Conversion of human fibroblasts to angioblast-like progenitor cells (2020) (10)
- Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging. (2022) (10)
- Keeping the Rhythm while Changing the Lyrics: Circadian Biology in Aging (2017) (9)
- The Molecular Harbingers of Early Mammalian Embryo Patterning (2016) (9)
- Generation of Induced Pluripotent Stem Cells from Human Renal Proximal Tubular Cells with Only Two Transcription Factors , Oct 4 and Sox 2 * (2012) (9)
- How the Body Tells Left from Right (1999) (9)
- Direct conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factors (2013) (9)
- Simultaneous detection and mutation surveillance of SARS-CoV-2 and multiple respiratory viruses by rapid field-deployable sequencing (2021) (8)
- Regeneration: making muscle from hPSCs (2014) (8)
- The labyrinth of nuclear reprogramming. (2011) (8)
- Will SCNT-ESCs be better than iPSCs for personalized regenerative medicine? (2013) (8)
- Generation of RRMS and PPMS specific iPSCs as a platform for modeling Multiple Sclerosis. (2021) (8)
- Elixir of Life: Thwarting Aging With Regenerative Reprogramming. (2018) (8)
- Reprogramming based gene therapy for inherited red blood cell disorders (2012) (8)
- Tailored chromatin modulation to promote tissue regeneration. (2019) (8)
- How the body tells left from right. (1999) (7)
- Trametinib for patients with advanced melanoma. (2012) (7)
- LINE-1 RNA causes heterochromatin erosion and is a target for amelioration of senescent phenotypes in progeroid syndromes (2022) (7)
- Reprogramming by lineage specifiers: blurring the lines between pluripotency and differentiation. (2014) (7)
- HOW THE BODY TE (1999) (7)
- 23 – Perspectives on the Evolutionary Origin of Tetrapod Limbs (2000) (7)
- Non-coding microRNAs for cardiac regeneration: Exploring novel alternatives to induce heart healing (2017) (7)
- Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo (2021) (7)
- Kidney organoids for disease modeling (2018) (7)
- Pluripotency of male germline stem cells (2011) (7)
- A stem cell aging framework, from mechanisms to interventions. (2022) (6)
- Advances in cellular reprogramming: moving toward a reprieve from immunogenicity. (2013) (6)
- Introduction to Cardiovascular Aging Compendium. (2018) (6)
- Extraembryonic Endoderm (XEN) Cells Capable of Contributing to Embryonic Chimeras Established from Pig Embryos (2020) (6)
- Organoids - Preclinical Models of Human Disease. Reply. (2019) (6)
- αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model (2020) (6)
- Erratum: Radical fringe positions the apical ectodermal ridge at the dorsoventral boundary of the vertebrate limb (1997) (6)
- Simultaneous Detection and Mutation Surveillance of SARS-CoV-2 and co-infections of multiple respiratory viruses by Rapid field-deployable sequencing (2020) (6)
- APOE4 drives inflammation in human astrocytes via TAGLN3 repression and NF-κB activation. (2022) (6)
- Cardiosphere-derived cells for heart regeneration (2012) (6)
- Use of Customizable Nucleases for Gene Editing and Other Novel Applications (2020) (5)
- Cotransplantation of MSCs and HSCs. (2013) (5)
- Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations (2019) (5)
- Conversion of pericytes to neurons: a new guest at the reprogramming convention (2013) (5)
- Gating neural development and aging via nuclear pores (2012) (5)
- Re: Serum miR-21 as a diagnostic and prognostic biomarker in colorectal cancer. (2014) (5)
- Stem cell research in Spain: if only they were windmills... (2009) (5)
- At the Heart of Genome Editing and Cardiovascular Diseases. (2018) (4)
- Epigenetic Mechanisms Controlling Mesodermal Specification (2012) (4)
- Human Organs from Animal Bodies. (2016) (4)
- Emerging role of RNA m6A modification in aging regulation (2022) (4)
- RE: stem cells loaded with multimechanistic oncolytic herpes simplex virus variants for brain tumor therapy. (2015) (4)
- Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing (2022) (4)
- Pig Chimeric Model with Human Pluripotent Stem Cells. (2019) (4)
- Subtractive hybridization and construction of cDNA libraries. (2008) (4)
- New march towards the regeneration of sensation and cognition: hear more, see more and learn more. (2013) (4)
- Unlocking Tissue Regenerative Potential by Epigenetic Reprogramming. (2021) (4)
- “TET-on” pluripotency (2013) (4)
- Time matters: Human blastoids resemble the sequence of blastocyst development (2022) (4)
- A recipe for targeted therapy in prostate cancer (2014) (3)
- c-MYC Triggers Lipid Remodelling During Early Somatic Cell Reprogramming to Pluripotency (2021) (3)
- Deciphering aging at three-dimensional genomic resolution (2022) (3)
- Cilia--where two Wnts collide. (2009) (3)
- Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway (2019) (3)
- Field approach to three-dimensional gene expression pattern characterization (2004) (3)
- Niche-less maintenance of HSCs by 2i (2013) (3)
- Summary Sp 8 and Sp 9 , two closely related buttonhead-like transcription factors , regulate Fgf 8 expression and limb outgrowth in vertebrate embryos (3)
- Design Approaches for Generating Organ Constructs. (2019) (3)
- Stem cell, CRISPR and HIV (2015) (3)
- Gametogenesis in a dish (2012) (3)
- Reprogramming strategies for the establishment of novel human cancer models (2016) (3)
- Reprogramming development and aging: cell differentiation as a malleable process. (2012) (3)
- Beating in a dish: new hopes for cardiomyocyte regeneration (2012) (3)
- Gene Editing in 3D Cultured Nephron Progenitor Cell Lines. (2019) (3)
- The XEN of reprogramming (2016) (3)
- hESC-derived pancreatic progenitors (2013) (3)
- Single-nucleus profiling unveils a geroprotective role of the FOXO3 in primate skeletal muscle aging. (2022) (3)
- Hyperthermia differentially affects specific human stem cells and their differentiated derivatives (2021) (3)
- Genetic Enhancement: a New Avenue to Combat Aging-related Diseases (2022) (3)
- Using Eukaryotic Expression Systems to Generate Human α1,3 Fucosyltransferases that Effectively Create Selectin-binding Glycans on Stem Cells. (2020) (3)
- 1 D as well as enhancing reprogramming by regulating p 53 and cyclin Rem 2 GTPase maintains survival of human embryonic stem cells Material Supplemental (2010) (2)
- Huntington's disease: Dancing in a dish (2012) (2)
- A β-galactosidase kiss of death for senescent cells (2020) (2)
- M-cadherin-mediated intercellular interactions activate satellite cell division (2013) (2)
- Purging and isolating pluripotent cells, “sweet” dreams become true? (2011) (2)
- Reprogramming development and aging: cell differentiation as a malleable process. (2012) (2)
- Single-cell Individual Complete mtDNA Sequencing Uncovers Hidden Mitochondrial Heterogeneity in Human and Mouse Oocytes (2020) (2)
- A single-nucleus transcriptomic atlas of primate testicular aging reveals exhaustion of the spermatogonial stem cell reservoir and loss of Sertoli cell homeostasis. (2022) (2)
- Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration (2022) (2)
- Author Correction: Conversion of human fibroblasts to angioblast-like progenitor cells (2020) (2)
- A complex epigenome-splicing crosstalk governs epithelial-to-mesenchymal transition in metastasis and brain development (2022) (2)
- Heart regeneration: a tale of cell reprogramming. (2013) (2)
- A chemical approach to “rewire” neural progenitor cells (2014) (2)
- Treating primary immunodeficiencies with defects in NK cells: from stem cell therapy to gene editing (2020) (2)
- First progeria monkey model generated using base editor (2020) (2)
- Hypoxia Induces Myocardial Regeneration in Zebrafish Running title : (2012) (2)
- TheT-boxgenes Tbx 4 and Tbx 5 regulate limb outgrowthand identity (1999) (1)
- The dawn of angiogenesis modeling: regenerating vasculature from human pluripotent stem cells (2012) (1)
- MicroRNA Regulation of Stem Cell Fate and Reprogramming (2013) (1)
- Direct conversion of human fi broblasts into retinal pigment epithelium-like cells by defi ned factors ESEARCH ARTICLE R (2013) (1)
- Regulation of Somatic Stem Cell Function by DNA Methylation and Genomic Imprinting (2013) (1)
- 2 BOVINE EMBRYONIC STEM-LIKE CELLS DERIVED FROM IN VITRO-PRODUCED BLASTOCYSTS. (2017) (1)
- The Alzheimer’s disease risk factor APOE4 drives pro-inflammation in human astrocytes via HDAC-dependent repression of TAGLN3 (2021) (1)
- iPSC Disease Modeling of Laminopathies (2016) (1)
- Genetically and metabolically corrected pluripotent stem cells from patients with mtDNA disease (2015) (1)
- Transient exposure to miR-203 expands the differentiation capacity of pluripotent stem cells (2020) (1)
- Differentiation protocol for generating functional pancreatic β cells from human pluripotent stem cells (2021) (1)
- Corrigendum to Brains, Genes, and Primates [Neuron 86, 617-631; May 6, 2015] (2015) (1)
- Age-related cardiopathies gene editing (2019) (1)
- 1 SIMPLE GENERATION OF HUMAN INDUCED PLURIPOTENT STEM CELLS USING POLY ( β-AMINO ESTERS ) AS NON-VIRAL GENE DELIVERY SYSTEM (2011) (1)
- GRP78 promotes stemness in normal and neoplastic cells (2019) (1)
- Differential display of eukaryotic mRNA. (2008) (1)
- Understanding the molecular basis for cardiomyocyte cell cycle regulation: new insights in cardiac regeneration after injury? (2010) (1)
- Conversion of pericytes to neurons: a new guest at the reprogramming convention (2013) (1)
- Subtractive hybridization and construction of cDNA libraries. (1999) (1)
- Erratum to: Generation of Pig iPS Cells: A Model for Cell Therapy (2013) (1)
- In vivo genome editing via the HITI method as a tool for gene therapy (2017) (1)
- Expanding the Toolbox and Targets for Gene Editing. (2021) (1)
- Worming toward transdifferentiation, one (Epigenetic) step at a time. (2014) (1)
- Single-cell transcriptomic atlas of mouse cochlear aging (2022) (1)
- Chemical combinations potentiate human pluripotent stem cell-derived 3D pancreatic progenitor clusters toward functional β cells (2021) (1)
- Human Organs from Animal Bodies. (2016) (1)
- Direct conversion of human fibroblasts into retinal pigment epithelium-like cells by defined factors (2014) (1)
- Development of de novo epithelialization method for treatment of cutaneous ulcers. (2019) (1)
- A single-cell transcriptomic atlas of exercise-induced anti-inflammatory and geroprotective effects across the body (2023) (1)
- Single-dose CRISPR–Cas9 therapy extends lifespan of mice with Hutchinson–Gilford progeria syndrome (2019) (1)
- Establishment of hepatic and neural differentiation platforms of Wilson’s disease specific induced pluripotent stem cells (2012) (1)
- Protocol for the generation of blastocyst-like structures from mouse extended pluripotent stem cells (2021) (1)
- Why it is important to study human–monkey embryonic chimeras in a dish (2022) (1)
- Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes (2013) (1)
- Gene expression pattern Spatially and temporally-restricted expression of two T-box genes during zebrafish embryogenesis (1999) (1)
- Exosomes from antler stem cells alleviate mesenchymal stem cell senescence and osteoarthritis (2021) (0)
- The lysine-speci fi c demethylase 1 is a novel substrate of protein kinase CK 2 O O F (2014) (0)
- Translating Stem Cells to the Clinic: From Modeling Disease to Cellular Products (2013) (0)
- The vertebrate brain develops from a bilaterally symmetric neural tube but later displays profound anatomical and functional asymmetries. Despite considerable progress in deciphering mechanisms of visceral organ laterality, the genetic pathways (2000) (0)
- Editors’ Preamble to The Journal of Cardiovascular Aging (2021) (0)
- Embryos at the core of life (2003) (0)
- proliferation of primordial germ cells Cell cycle gene-specific control of transcription has a critical role in Material Supplemental (2012) (0)
- Maintenance of Embryonic Stem Cell Pluripotency by Nanog-Mediated Dedifferentiation of Committed Mesoderm Progenitors (2009) (0)
- [Resetting Parkinson's disease patient-derived cells to unveil new pathological marks]. (2013) (0)
- Key Experiments in Practical Developmental Biology: Induction of ectopic limb outgrowth in chick with FGF-8 (2005) (0)
- The ageing epigenome and its rejuvenation (2020) (0)
- Mutations in foregut SOX2+ cells induce efficient proliferation via CXCR2 pathway (2019) (0)
- Understanding the genetics behind complex human disease with large-scale iPSC collections (2017) (0)
- Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells (2019) (0)
- New Life is coming: committed to improving human health (2022) (0)
- Towards capturing of totipotency (2022) (0)
- Towards precise, safe genome editing (2019) (0)
- British Society for Gene and Cell Therapy (BSGCT) Conference Abstracts Royal Holloway University of London 17–19 April, 2013 (2013) (0)
- Application of Gene-Editing Technologies in Embryos and Their Potential for Gene Therapy (2019) (0)
- Building functional circuits in multispecies brains (2023) (0)
- Precise in vivo genome editing via single homology arm donor mediated intron-targeting gene integration for genetic disease correction (2019) (0)
- EVI1 Is Activated During the Generation of Induced Pluripotent Stem (iPS) Cells. (2009) (0)
- m6A epitranscriptomic regulation of tissue homeostasis during primate aging. (2023) (0)
- Genome editing in human pluripotent stem cells: a systematic approach unrevealing pancreas development and disease. (2016) (0)
- A β-galactosidase kiss of death for senescent cells (2020) (0)
- Skeletal muscle regeneration in Xenopus tadpoles and zebrafish larvae (2012) (0)
- CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs (2017) (0)
- Organ Regeneration and Anti‐Aging Strategies (2018) (0)
- Towards precise, safe genome editing (2019) (0)
- Opening up the black box of human cell plasticity (2022) (0)
- Single-cell individual full-length mtDNA sequencing by iMiGseq uncovers unexpected heteroplasmy shifts in mtDNA editing. (2023) (0)
- Cell surface GRP78 promotes stemness in normal and neoplastic cells (2020) (0)
- Therapeutic strategy for spinal muscular atrophy by combining gene supplementation and genome editing (2023) (0)
- At the crossroads of targeted treatment and resistance in melanoma. (2013) (0)
- From the blogosphere (2009) (0)
- FOXO3-engineered human mesenchymal progenitor cells efficiently promote cardiac repair after myocardial infarction (2020) (0)
- In vivo reprogramming of wound-resident cells generates skin epithelial tissue (2018) (0)
- Transcriptomic profiling fuels the derivation of stable pig epiblast stem cells (2022) (0)
- Retroviral Vector-Based Approaches for the Generation of Human Induced Pluripotent Stem Cells from Fibroblasts and Keratinocytes (2011) (0)
- Epiblast grafting and in vitro embryo culture (2015) (0)
- Treating primary immunodeficiencies with defects in NK cells: from stem cell therapy to gene editing (2020) (0)
- Human induced pluripotent stem cells derived hepatocytes: rising promise for disease modeling, drug development and cell therapy (2012) (0)
- Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations (2019) (0)
- Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor (2022) (0)
- Compound screening platform using human induced pluripotent stem cells to identify small molecules that promote chondrogenesis (2012) (0)
- Myc Supports Self-Renewal of Basal Cells in the Esophageal Epithelium (2022) (0)
- CHAPTER 254 – Control of Left-Right (L/R) Determination in Vertebrates by the Hedgehog Signaling Pathway (2003) (0)
- Gathering by the Red Sea highlights links between environment and epigenetics (2017) (0)
- Novel cell lines-derived from mouse primordial germ cells (2017) (0)
- DIABETIC STUDIES The Review of Turning Human Epidermis Into Pancreatic Endoderm (2010) (0)
- Perspective The labyrinth of nuclear reprogramming (2011) (0)
- Left‐Right Asymmetry in Humans (2006) (0)
- Sall genes regulates limb patterning through modulation of region‐specific Hox activities in mice (2008) (0)
- Quantitative haplotype-resolved analysis of mitochondrial DNA heteroplasmy in Human single oocytes, blastoids, and pluripotent stem cells. (2023) (0)
- Direct reprogramming of porcine fibroblasts to neural progenitor cells (2014) (0)
- Histone H1 variants content during the differentiation of human embryonic stem cells and the reprogramming of keratinocytes to pluripotency (2011) (0)
- Plucked hair: how to get stem cells and induced pluripotent stem cells for future clinical applications (2012) (0)
- Review Article No factor left behind: generation of transgene-free induced pluripotent stem cells (2012) (0)
- Author Correction: Wiskott-Aldrich syndrome protein forms nuclear condensates and regulates alternative splicing (2022) (0)
- A Gas-only Bioreactor System Maintains Stable Culture Environments and Reveals that Moderate pH deviations Trigger Transcriptome-wide Responses in Human Cells Cultured in Physioxia and Physiological Buffers (2022) (0)
- Special Issue: Imaging In Bioinformatics (2002) (0)
- Adenine base editing to mimic or correct disease mutations in rodents (2018) (0)
- Chimera-competent eXtra-Embryonic eNdoderm (XEN) cells established from pig embryos (2020) (0)
- Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells (2019) (0)
- Abstract 1990: Aberrant cell surface expression of GRP78 in breast cancer cells marks a stem-like population that has increased metastatic potentialin vivo (2018) (0)
- Lineage Reprogramming Toward Kidney Regeneration (2017) (0)
- αKLOTHO and sTGFβR2 treatment counteract the osteoarthritic phenotype developed in a rat model (2020) (0)
- N ov 2 00 4 A Novel Field Approach to 3 D Gene Expression Pattern Characterization (2008) (0)
- Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes (2014) (0)
- Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome (2018) (0)
- Hyperthermia differentially affects specific human stem cells and their differentiated derivatives (2021) (0)
- Human cord blood reprogrammed into embryonic‐like stem cells (2011) (0)
- Rejuvenation of Tissue Stem Cells by Intrinsic and Extrinsic Factors (2022) (0)
- SELECTED ORAL COMMUNICATION SESSION, SESSION 68: EMBRYOLOGY - THE OOCYTE Wednesday 6 July 2011 14:00 - 15:45 (2011) (0)
- miRNA 125b Enhances the differentiation and Functionality of in Vitro Generated Human Hematopoietic Progenitor Cells (2012) (0)
- Deconstructing the pluripotency gene regulatory network (2018) (0)
- The efficiency of the human oocyte after ovarian stimulation O-262 Evidence based safety in ART: Principles, Paradigms and Practice (2011) (0)
- Abstract 1932: Parallel functions of the endoplasmic reticulum chaperone protein GRP78 in tumorigenesis and the induction of pluripotency (2014) (0)
- Induced Pluripotent Stem Cells (iPSC) from Cord Blood CD133 + Cells Using Oct4 and Sox2 (2011) (0)
- Single-cell omics in ageing: a young and growing field (2020) (0)
- Neuron Perspective Brains , Genes , and Primates (2015) (0)
- Ma et al. reply (2018) (0)
- CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs (2017) (0)
- THE EMBRYO 3 Setting the Cascade in Motion : Establishing Left – Right Differences (2000) (0)
- A role for somatic mutations in the evolution of lifespan (2022) (0)
- R ESEARCH Mutations in foregut SOX2 + cells induce ef fi cient proliferation via CXCR2 pathway (2019) (0)
- Regulation of Stem Cell Aging by Metabolic and Epigenetic Factors (2017) (0)
- Modeling xeroderma pigmentosum associated neurological pathologies with patients-derived iPSCs (2016) (0)
- Gene Editing Nuclear and Mitochondrial DNA (2014) (0)
- 4 DEVELOPMENTAL OUTCOMES AND EFFICIENCY OF TWO CRISPR/Cas9 MICROINJECTION METHODS IN BOVINE ZYGOTES (2015) (0)
- A widely adaptable approach to generate integration-free iPSCs from non-invasively acquired human somatic cells (2014) (0)
- Correction to: Treating primary immunodeficiencies with defects in NK cells: from stem cell therapy to gene editing (2021) (0)
- On the Search for Reliable Human Aging Models: Understanding Aging by Nuclear Reprogramming (2013) (0)
- The Use of Autologous Fibroblasts for the Reconstruction of the Anterior Cruciate Ligament Tears (2015) (0)
- Nodal / BMP 2 Chimeras Mimic Signal Transduction : (2014) (0)
- Reprogramming toward kidney regeneration: New technologies and future promises (0)
- Derivation and characterization of chimera-competent eXtra-Embryonic eNdoderm (XEN) cells from pig blastocysts (2020) (0)
- Generation of Induced Pluripotent Stem Cells from Human Renal Proximal Tubular Cells with Only Two Transcription (2012) (0)
- ROLE OF RIGF (RETINOIC ACID INDUCED GROWTH FACTOR), A NOVEL MEMBER OF VASCULAR ENDOTHELIAL GROWTH FACTOR FAMILY ON THE DEVELOPING CHICK LIMB BUD(Developmental Biology)(Proceedings of the Seventieth Annual Meeting of the Zoological Society of Japan) (1999) (0)
- Correction to: Treating primary immunodeficiencies with defects in NK cells: from stem cell therapy to gene editing (2021) (0)
- Interspecies chimeric complementation for the generation of functional human tissues and organs in large animal hosts (2016) (0)
- Stem cell energetics (2014) (0)
- FOXM1 delays senescence and extends lifespan (2022) (0)
- Keratinocyte-Induced Pluripotent Stem Cells: From Hair to Where? (2011) (0)
- Adenine base editing to mimic or correct disease mutations in rodents (2018) (0)
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