Juan S. Bonifacino
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Biology
Juan S. Bonifacino's Degrees
- Bachelors Biology University of Buenos Aires
- Masters Cell Biology University of Buenos Aires
- PhD Cell Biology University of Buenos Aires
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(Suggest an Edit or Addition)Juan S. Bonifacino's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Imaging Intracellular Fluorescent Proteins at Nanometer Resolution (2006) (7397)
- Signals for sorting of transmembrane proteins to endosomes and lysosomes. (2003) (2085)
- The Mechanisms of Vesicle Budding and Fusion (2004) (1684)
- Rapid redistribution of Golgi proteins into the ER in cells treated with brefeldin A: Evidence for membrane cycling from Golgi to ER (1989) (1611)
- Interaction of tyrosine-based sorting signals with clathrin-associated proteins. (1995) (980)
- Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
- Sorting of lysosomal proteins. (2009) (704)
- Ubiquitin and the control of protein fate in the secretory and endocytic pathways. (1998) (682)
- Altered trafficking of lysosomal proteins in Hermansky-Pudlak syndrome due to mutations in the beta 3A subunit of the AP-3 adaptor. (1999) (674)
- Retrograde transport from endosomes to the trans-Golgi network (2006) (645)
- Role of the mammalian retromer in sorting of the cation-independent mannose 6-phosphate receptor (2004) (589)
- Adaptor-related proteins. (2001) (547)
- A Novel Clathrin Adaptor Complex Mediates Basolateral Targeting in Polarized Epithelial Cells (1999) (516)
- Lysosomes as dynamic regulators of cell and organismal homeostasis (2019) (486)
- Lysosome‐related organelles (2000) (481)
- Adaptins: the final recount. (2001) (463)
- The contribution of VHL substrate binding and HIF1-alpha to the phenotype of VHL loss in renal cell carcinoma. (2002) (460)
- Molecular Bases for the Recognition of Tyrosine-based Sorting Signals (1999) (436)
- Degradation from the endoplasmic reticulum: Disposing of newly synthesized proteins (1988) (429)
- Linking cargo to vesicle formation: receptor tail interactions with coat proteins. (1997) (425)
- Coat proteins: shaping membrane transport (2003) (423)
- Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7 (2008) (421)
- Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160. (1988) (418)
- Sorting of Mannose 6-Phosphate Receptors Mediated by the GGAs (2001) (399)
- GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex. (2000) (394)
- AP‐3: an adaptor‐like protein complex with ubiquitous expression (1997) (388)
- The GGA proteins: adaptors on the move (2004) (382)
- Association of the AP-3 adaptor complex with clathrin. (1998) (381)
- Tyrosine phosphorylation controls internalization of CTLA-4 by regulating its interaction with clathrin-associated adaptor complex AP-2. (1997) (353)
- Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae. (2002) (339)
- Protein targeting by tyrosine- and di-leucine-based signals: evidence for distinct saturable components (1996) (333)
- Failure to synthesize the T Cell CD3-ζ chain: Structure and function of a partial T cell receptor complex (1988) (327)
- The T cell antigen receptor: insights into organelle biology. (1990) (325)
- Mechanisms and functions of lysosome positioning (2016) (324)
- A tubular EHD1‐containing compartment involved in the recycling of major histocompatibility complex class I molecules to the plasma membrane (2002) (310)
- Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation (1989) (295)
- Structural Determinants of Interaction of Tyrosine-based Sorting Signals with the Adaptor Medium Chains* (1996) (288)
- Sequence requirements for the recognition of tyrosine‐based endocytic signals by clathrin AP‐2 complexes. (1996) (273)
- Functional architecture of the retromer cargo-recognition complex (2007) (273)
- The GGAs Promote ARF-Dependent Recruitment of Clathrin to the TGN (2001) (266)
- AP-4, a Novel Protein Complex Related to Clathrin Adaptors* (1999) (266)
- BORC, a multisubunit complex that regulates lysosome positioning. (2015) (254)
- Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes. (2005) (252)
- The Medium Subunits of Adaptor Complexes Recognize Distinct but Overlapping Sets of Tyrosine-based Sorting Signals* (1998) (247)
- Colocalized transmembrane determinants for ER degradation and subunit assembly explain the intracellular fate of TCR chains (1990) (245)
- Cargo recognition in clathrin-mediated endocytosis. (2013) (245)
- Interactions of GGA3 with the ubiquitin sorting machinery (2004) (243)
- Membrane protein association by potential intrarnembrane charge pairs (1991) (238)
- Localization of TGN38 to the trans-Golgi network: involvement of a cytoplasmic tyrosine-containing sequence (1993) (237)
- Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 γ–σ1 and AP-3 δ–σ3 hemicomplexes (2003) (234)
- Novel Aspects of Degradation of T Cell Receptor Subunits from the Endoplasmic Reticulum (ER) in T Cells: Importance of Oligosaccharide Processing, Ubiquitination, and Proteasome-dependent Removal from ER Membranes (1998) (232)
- μ1B, a novel adaptor medium chain expressed in polarized epithelial cells 1 (1999) (229)
- Sorting of the Alzheimer's disease amyloid precursor protein mediated by the AP-4 complex. (2010) (227)
- Interchangeable but Essential Functions of SNX1 and SNX2 in the Association of Retromer with Endosomes and the Trafficking of Mannose 6-Phosphate Receptors (2006) (221)
- A lysosomal targeting signal in the cytoplasmic tail of the beta chain directs HLA-DM to MHC class II compartments (1995) (220)
- Germline mutations in PRKCSH are associated with autosomal dominant polycystic liver disease (2003) (218)
- An acidic sequence within the cytoplasmic domain of furin functions as a determinant of trans‐Golgi network localization and internalization from the cell surface. (1995) (216)
- Coatomer-dependent protein delivery to lipid droplets (2009) (215)
- Transmembrane helical interactions and the assembly of the T cell receptor complex. (1990) (214)
- Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins. (2005) (214)
- Downregulation of CD4 by Human Immunodeficiency Virus Type 1 Nef Is Dependent on Clathrin and Involves Direct Interaction of Nef with the AP2 Clathrin Adaptor (2007) (214)
- The molecular machinery for lysosome biogenesis * (2001) (214)
- Copper‐dependent degradation of the Saccharomyces cerevisiae plasma membrane copper transporter Ctr1p in the apparent absence of endocytosis. (1996) (212)
- ADP-Ribosylation Factor 1 (ARF1) Regulates Recruitment of the AP-3 Adaptor Complex to Membranes (1998) (209)
- Restricted Location of PSEN2/γ-Secretase Determines Substrate Specificity and Generates an Intracellular Aβ Pool (2016) (208)
- Pre-Golgi degradation of newly synthesized T-cell antigen receptor chains: intrinsic sensitivity and the role of subunit assembly (1989) (208)
- Adaptor proteins involved in polarized sorting (2014) (207)
- Current protocols in cell biology (1998) (202)
- Structural basis for ubiquitin recognition and autoubiquitination by Rabex-5 (2006) (199)
- Role of transmembrane domain interactions in the assembly of class II MHC molecules. (1992) (196)
- Role of potentially charged transmembrane residues in targeting proteins for retention and degradation within the endoplasmic reticulum. (1991) (195)
- A Membrane-proximal Tyrosine-based Signal Mediates Internalization of the HIV-1 Envelope Glycoprotein via Interaction with the AP-2 Clathrin Adaptor* (1998) (194)
- A peptide sequence confers retention and rapid degradation in the endoplasmic reticulum. (1990) (192)
- Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics. (2002) (189)
- Biosynthesis, glycosylation, movement through the Golgi system, and transport to lysosomes by an N-linked carbohydrate-independent mechanism of three lysosomal integral membrane proteins. (1986) (188)
- Interaction of endocytic signals from the HIV-1 envelope glycoprotein complex with members of the adaptor medium chain family. (1997) (188)
- Failure of trafficking and antigen presentation by CD1 in AP-3-deficient cells. (2002) (186)
- Pairwise, cooperative and inhibitory interactions describe the assembly and probable structure of the T‐cell antigen receptor. (1991) (186)
- Degradation of proteins within the endoplasmic reticulum. (1991) (173)
- The cytoplasmic domain mediates localization of furin to the trans- Golgi network en route to the endosomal/lysosomal system (1994) (171)
- Structural basis for acidic-cluster-dileucine sorting-signal recognition by VHS domains (2002) (165)
- PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal. (2007) (165)
- Genetic analyses of adaptin function from yeast to mammals. (2002) (164)
- Multilayered Mechanism of CD4 Downregulation by HIV-1 Vpu Involving Distinct ER Retention and ERAD Targeting Steps (2010) (164)
- The retromer complex and clathrin define an early endosomal retrograde exit site (2007) (162)
- Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes. (2008) (162)
- Regulating the retention of T-cell receptor alpha chain variants within the endoplasmic reticulum: Ca(2+)-dependent association with BiP (1991) (162)
- The retromer subunit Vps26 has an arrestin fold and binds Vps35 through its C-terminal domain (2006) (159)
- Mechanism of Acidification of the trans-Golgi Network (TGN) (1998) (158)
- Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery. (2001) (156)
- Human Vam6p promotes lysosome clustering and fusion in vivo (2001) (153)
- Structural Mechanism for Cargo Recognition by the Retromer Complex (2016) (152)
- BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks. (2016) (152)
- Altered expression of a novel adaptin leads to defective pigment granule biogenesis in the Drosophila eye color mutant garnet (1997) (151)
- Structural Basis for Recruitment and Activation of the AP-1 Clathrin Adaptor Complex by Arf1 (2013) (147)
- The clathrin adaptor AP-1A mediates basolateral polarity. (2012) (142)
- Mu1B, a novel adaptor medium chain expressed in polarized epithelial cells. (1999) (140)
- Moving and positioning the endolysosomal system. (2017) (140)
- Dual Roles of the Mammalian GARP Complex in Tethering and SNARE Complex Assembly at the trans-Golgi Network (2009) (139)
- Divalent interaction of the GGAs with the Rabaptin‐5–Rabex‐5 complex (2003) (137)
- Transport according to GARP: receiving retrograde cargo at the trans-Golgi network. (2011) (134)
- Clathrin Adaptor AP-2 Is Essential for Early Embryonal Development (2005) (134)
- BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon (2017) (134)
- Signal-binding Specificity of the μ4 Subunit of the Adaptor Protein Complex AP-4* (2001) (131)
- Morphology and dynamics of clathrin/GGA1-coated carriers budding from the trans-Golgi network. (2003) (130)
- The Transmembrane Domain of a Carboxyl-terminal Anchored Protein Determines Localization to the Endoplasmic Reticulum* (1997) (127)
- β3A-adaptin, a Subunit of the Adaptor-like Complex AP-3* (1997) (125)
- Involvement of clathrin and AP-2 in the trafficking of MHC class II molecules to antigen-processing compartments (2005) (121)
- The Rab5 Guanine Nucleotide Exchange Factor Rabex-5 Binds Ubiquitin (Ub) and Functions as a Ub Ligase through an Atypical Ub-interacting Motif and a Zinc Finger Domain* (2006) (118)
- Association with BiP and aggregation of class II MHC molecules synthesized in the absence of invariant chain. (1994) (118)
- BLOC-3, a Protein Complex Containing the Hermansky-Pudlak Syndrome Gene Products HPS1 and HPS4* (2003) (116)
- Co-localization of the TSC2 product tuberin with its target Rap1 in the Golgi apparatus. (1996) (114)
- Transmembrane helical interactions: zeta chain dimerization and functional association with the T cell antigen receptor. (1992) (111)
- Selective degradation of T cell antigen receptor chains retained in a pre-Golgi compartment (1988) (111)
- Disulfide linkage of the zeta and eta chains of the T cell receptor. Possible identification of two structural classes of receptors. (1988) (110)
- A new variant of Hermansky-Pudlak syndrome due to mutations in a gene responsible for vesicle formation. (2000) (107)
- Molecular Characterization of the Protein Encoded by the Hermansky-Pudlak Syndrome Type 1 Gene* (2000) (105)
- Mechanisms of CD4 downregulation by the Nef and Vpu proteins of primate immunodeficiency viruses. (2007) (104)
- EARP, a multisubunit tethering complex involved in endocytic recycling (2015) (103)
- Functional and physical interactions of the adaptor protein complex AP‐4 with ADP‐ribosylation factors (ARFs) (2001) (98)
- How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4 (2014) (98)
- Assembly of the Biogenesis of Lysosome-related Organelles Complex-3 (BLOC-3) and Its Interaction with Rab9* (2010) (97)
- Functional Domain Mapping of the Clathrin-associated Adaptor Medium Chains μ1 and μ2* (1997) (97)
- AP-4 mediates export of ATG9A from the trans-Golgi network to promote autophagosome formation (2017) (96)
- Adaptor and clathrin exchange at the plasma membrane and trans-Golgi network. (2003) (96)
- A Diacidic Motif in Human Immunodeficiency Virus Type 1 Nef Is a Novel Determinant of Binding to AP-2 (2007) (95)
- Conservation and Diversification of Dileucine Signal Recognition by Adaptor Protein (AP) Complex Variants* (2010) (95)
- BORC coordinates encounter and fusion of lysosomes with autophagosomes (2017) (93)
- Role of microtubules in the organization and localization of the Golgi apparatus (1984) (93)
- Signal-Mediated, AP-1/Clathrin-Dependent Sorting of Transmembrane Receptors to the Somatodendritic Domain of Hippocampal Neurons (2012) (93)
- Two integral membrane proteins located in the cis-middle and trans-part of the Golgi system acquire sialylated N-linked carbohydrates and display different turnovers and sensitivity to cAMP-dependent phosphorylation (1987) (91)
- Mutational analysis of the fusion peptide of the human immunodeficiency virus type 1: identification of critical glycine residues. (1996) (90)
- A Ragulator–BORC interaction controls lysosome positioning in response to amino acid availability (2017) (90)
- Serine Residues in the Cytosolic Tail of the T-cell Antigen Receptor α-Chain Mediate Ubiquitination and Endoplasmic Reticulum-associated Degradation of the Unassembled Protein* (2010) (89)
- Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1. (2003) (87)
- Cappuccino, a mouse model of Hermansky-Pudlak syndrome, encodes a novel protein that is part of the pallidin-muted complex (BLOC-1). (2003) (86)
- Polycystic liver disease is a disorder of cotranslational protein processing. (2005) (84)
- Sorting of Dendritic and Axonal Vesicles at the Pre-axonal Exclusion Zone. (2015) (84)
- T cell CD3-zeta eta heterodimer expression and coupling to phosphoinositide hydrolysis. (1988) (83)
- The Vps27/Hse1 complex is a GAT domain-based scaffold for ubiquitin-dependent sorting. (2007) (83)
- Ang2/Fat-Free Is a Conserved Subunit of the Golgi-associated Retrograde Protein Complex (2010) (82)
- Subunit interactions within the T-cell antigen receptor: clues from the study of partial complexes. (1988) (80)
- Localization of Endogenous Furin in Cultured Cell Lines (1997) (77)
- Structure of Human ATG9A, the Only Transmembrane Protein of the Core Autophagy Machinery. (2020) (77)
- Ubiquitin binding and conjugation regulate the recruitment of Rabex‐5 to early endosomes (2008) (77)
- Mutations within the human immunodeficiency virus type 1 gp160 envelope glycoprotein alter its intracellular transport and processing. (1991) (75)
- Basolateral Sorting of Furin in MDCK Cells Requires a Phenylalanine-Isoleucine Motif Together with an Acidic Amino Acid Cluster (1999) (74)
- CD1a and MHC Class I Follow a Similar Endocytic Recycling Pathway (2008) (74)
- Basolateral sorting of the coxsackie and adenovirus receptor through interaction of a canonical YXXΦ motif with the clathrin adaptors AP-1A and AP-1B (2012) (71)
- Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complex (2010) (71)
- Aggregation As a Determinant of Protein Fate in Post-Golgi Compartments: Role of the Luminal Domain of Furin in Lysosomal Targeting (1997) (70)
- Pallidin is a Component of a Multi‐Protein Complex Involved in the Biogenesis of Lysosome‐related Organelles (2002) (69)
- Rab5 and its effector FHF contribute to neuronal polarity through dynein-dependent retrieval of somatodendritic proteins from the axon (2016) (68)
- Deubiquitinases Sharpen Substrate Discrimination during Membrane Protein Degradation from the ER (2013) (68)
- Structural Requirements for Function of Yeast GGAs in Vacuolar Protein Sorting, α-Factor Maturation, and Interactions with Clathrin (2001) (67)
- Phosphoregulation of sorting signal–VHS domain interactions by a direct electrostatic mechanism (2002) (67)
- Human Immunodeficiency Virus Type 1 Nef Protein Targets CD4 to the Multivesicular Body Pathway (2009) (67)
- Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, gamma-ear-containing, ADP-ribosylation-factor-binding proteins. (2005) (67)
- Adaptor protein 2–mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing (2012) (67)
- Canonical interaction of cyclin G associated kinase with adaptor protein 1 regulates lysosomal enzyme sorting. (2007) (66)
- GGA and Arf proteins modulate retrovirus assembly and release. (2008) (66)
- Novel post-translational regulation of TCR expression in CD4+CD8+ thymocytes influenced by CD4 (1990) (64)
- Defective expression of the μ3 subunit of the AP-3 adaptor complex in the Drosophila pigmentation mutant carmine (1999) (64)
- Crystallographic and functional analysis of the ESCRT-I /HIV-1 Gag PTAP interaction. (2010) (64)
- Ultrastructure of Long‐Range Transport Carriers Moving from the trans Golgi Network to Peripheral Endosomes (2006) (63)
- The Hermansky-Pudlak syndrome 1 (HPS1) and HPS2 genes independently contribute to the production and function of platelet dense granules, melanosomes, and lysosomes. (2002) (63)
- Definition of the Consensus Motif Recognized by γ-Adaptin Ear Domains* (2004) (63)
- Altered distribution of ATG9A and accumulation of axonal aggregates in neurons from a mouse model of AP-4 deficiency syndrome (2018) (63)
- A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis (2019) (62)
- Insights into the Biogenesis of Lysosome‐Related Organelles from the Study of the Hermansky‐Pudlak Syndrome (2004) (62)
- Uncleaved signals for glycosylphosphatidylinositol anchoring cause retention of precursor proteins in the endoplasmic reticulum. (1993) (62)
- Transmembrane Domain Determinants of CD4 Downregulation by HIV-1 Vpu (2011) (62)
- Distinct requirements for the AP-3 adaptor complex in pigment granule and synaptic vesicle biogenesis in Drosophila melanogaster (2000) (61)
- IN SITU MEASUREMENTS OF pH USING RETRIEVAL OF TGN38 AND FURIN FROM THE CELL SURFACE (1998) (60)
- Molecular characterization of hepatocystin, the protein that is defective in autosomal dominant polycystic liver disease. (2004) (59)
- Utilization of the indirect lysosome targeting pathway by lysosome-associated membrane proteins (LAMPs) is influenced largely by the C-terminal residue of their GYXXphi targeting signals. (1999) (59)
- Lysosome Positioning Influences mTORC2 and AKT Signaling. (2019) (58)
- Differential recognition of a dileucine-based sorting signal by AP-1 and AP-3 reveals a requirement for both BLOC-1 and AP-3 in delivery of OCA2 to melanosomes (2012) (57)
- The adaptor protein-1 μ1B subunit expands the repertoire of basolateral sorting signal recognition in epithelial cells. (2013) (57)
- The trans-Golgi network accessory protein p56 promotes long-range movement of GGA/clathrin-containing transport carriers and lysosomal enzyme sorting. (2007) (56)
- Anchors aweigh: protein localization and transport mediated by transmembrane domains (2013) (55)
- A Basic Patch on α-Adaptin Is Required for Binding of Human Immunodeficiency Virus Type 1 Nef and Cooperative Assembly of a CD4-Nef-AP-2 Complex (2009) (55)
- Reduced pigmentation (rp), a mouse model of Hermansky-Pudlak syndrome, encodes a novel component of the BLOC-1 complex. (2004) (55)
- Assembly and Architecture of Biogenesis of Lysosome-related Organelles Complex-1 (BLOC-1)* (2011) (54)
- The clathrin adaptor complexes as a paradigm for membrane‐associated allostery (2013) (54)
- Phagolysosome resolution requires contacts with the endoplasmic reticulum and phosphatidylinositol-4-phosphate signalling (2019) (54)
- TGN38 recycles basolaterally in polarized Madin-Darby canine kidney cells. (1994) (53)
- CD4 Down-regulation by HIV-1 and Simian Immunodeficiency Virus (SIV) Nef Proteins Involves Both Internalization and Intracellular Retention Mechanisms* (2005) (53)
- A permeabilized cell system identifies the endoplasmic reticulum as a site of protein degradation (1991) (53)
- Transient Aggregation of Major Histocompatibility Complex Class II Chains during Assembly in Normal Spleen Cells (*) (1995) (52)
- Association between Rare Variants in AP4E1, a Component of Intracellular Trafficking, and Persistent Stuttering. (2015) (52)
- Segregation in the Golgi complex precedes export of endolysosomal proteins in distinct transport carriers (2017) (52)
- Coatopathies: Genetic Disorders of Protein Coats. (2019) (46)
- Immunoprecipitation (2016) (46)
- Polarized sorting of the copper transporter ATP7B in neurons mediated by recognition of a dileucine signal by AP-1 (2015) (45)
- Association and dissociation of the murine T cell receptor associated protein (TRAP). Early events in the biosynthesis of a multisubunit receptor. (1988) (44)
- Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism. (2000) (42)
- Neuronal functions of adaptor complexes involved in protein sorting (2018) (42)
- Transmembrane domain length affects charge-mediated retention and degradation of proteins within the endoplasmic reticulum. (1993) (41)
- Mechanisms of signal-mediated protein sorting in the endocytic and secretory pathways. (1996) (41)
- Structure of the ovarian lactogen receptors. Analysis with bifunctional cross-linking reagents. (1984) (40)
- Definition of the consensus motif recognized by gamma-adaptin ear domains. (2004) (39)
- Mechanisms of Polarized Organelle Distribution in Neurons (2016) (39)
- Negative regulation of autophagy by UBA6-BIRC6–mediated ubiquitination of LC3 (2019) (39)
- The Parkinson’s Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network (2020) (39)
- Reversal of fortune for nascent proteins (1996) (39)
- A widely distributed nuclear protein immunologically related to the microtubule-associated protein MAP1 is associated with the mitotic spindle. (1985) (37)
- Trafficking of major histocompatibility complex class II molecules in human B-lymphoblasts deficient in the AP-3 adaptor complex. (2000) (37)
- Structural Basis for the Recognition of Tyrosine-based Sorting Signals by the μ3A Subunit of the AP-3 Adaptor Complex* (2013) (37)
- Gga2 Mediates Sequential Ubiquitin-independent and Ubiquitin-dependent Steps in the Trafficking of ARN1 from the trans-Golgi Network to the Vacuole* (2009) (37)
- Functional characterization of protein-sorting machineries at the trans-Golgi network in Drosophila melanogaster (2010) (37)
- Recognition of accessory protein motifs by the γ-adaptin ear domain of GGA3 (2003) (36)
- Internalization and recycling to serotonin-containing granules of the 80K integral membrane protein exposed on the surface of secreting rat basophilic leukaemia cells. (1989) (35)
- AP‐1A Controls Secretory Granule Biogenesis and Trafficking of Membrane Secretory Granule Proteins (2014) (35)
- HIV-1 Vpu Accessory Protein Induces Caspase-mediated Cleavage of IRF3 Transcription Factor* (2014) (34)
- The Trihelical Bundle Subdomain of the GGA Proteins Interacts with Multiple Partners through Overlapping but Distinct Sites* (2004) (34)
- Study of the transit of an integral membrane protein from secretory granules through the plasma membrane of secreting rat basophilic leukemia cells using a specific monoclonal antibody (1986) (34)
- Protein Trafficking (2005) (33)
- Metabolic Labeling with Amino Acids (1998) (33)
- A Neurodevelopmental Disorder Caused by Mutations in the VPS51 Subunit of the GARP and EARP Complexes (2018) (33)
- Molecular mechanism for the subversion of the retromer coat by the Legionella effector RidL (2017) (32)
- Interaction of HIV-1 Nef Protein with the Host Protein Alix Promotes Lysosomal Targeting of CD4 Receptor* (2014) (32)
- Direct binding to Rsp5p regulates ubiquitination-independent vacuolar transport of Sna3p. (2007) (32)
- Cloning, expression, and localization of a novel γ‐adaptin‐like molecule (1998) (32)
- Vesicular transport earns a Nobel. (2014) (30)
- α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes (2021) (30)
- Epidermal Growth Factor-Dependent Phosphorylation of the GGA3 Adaptor Protein Regulates Its Recruitment to Membranes (2005) (29)
- Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons (2020) (29)
- Structural basis for the interaction of the Golgi-Associated Retrograde Protein Complex with the t-SNARE Syntaxin 6. (2013) (28)
- Characterization of human somatotropin binding to detergent-solubilized lactogenic receptors from rat liver. (1981) (28)
- Endosome-Specific Localization and Function of the ARF Activator GNOM (2003) (26)
- Lactogen receptors in rat Leydig cells: analysis of their structure with bifunctional cross-linking reagents. (1985) (25)
- An ear-core interaction regulates the recruitment of the AP-3 complex to membranes. (2004) (24)
- Bivalent Motif-Ear Interactions Mediate the Association of the Accessory Protein Tepsin with the AP-4 Adaptor Complex* (2015) (24)
- Downregulation of CD 4 by Human Immunodeficiency Virus Type 1 Nef Is Dependent on Clathrin and Involves Direct Interaction of Nef with the AP 2 Clathrin Adaptor (2007) (22)
- In vitro assays of Arf1 interaction with GGA proteins. (2005) (22)
- A myosin-7B–dependent endocytosis pathway mediates cellular entry of α-synuclein fibrils and polycation-bearing cargos (2020) (22)
- Subcellular Fractionation and Isolation of Organelles (2005) (22)
- TSSC1 is novel component of the endosomal retrieval machinery (2016) (22)
- A Myosin-7B dependent endocytosis pathway mediates cellular entry of α-Synuclein fibrils and polycation-bearing cargos (2020) (21)
- Co-assembly of Viral Envelope Glycoproteins Regulates Their Polarized Sorting in Neurons (2014) (21)
- SNX19 restricts endolysosome motility through contacts with the endoplasmic reticulum (2021) (21)
- Recognition of accessory protein motifs by the gamma-adaptin ear domain of GGA3. (2003) (21)
- ARL8 Relieves SKIP Autoinhibition to Enable Coupling of Lysosomes to Kinesin-1 (2020) (21)
- Supporting Online Material for Imaging Intracellular Fluorescent Proteins at Nanometer Resolution (2006) (20)
- ARFRP1 functions upstream of ARL1 and ARL5 to coordinate recruitment of distinct tethering factors to the trans-Golgi network (2019) (20)
- The autophagy protein ATG9A enables lipid mobilization from lipid droplets (2021) (20)
- Disruption of the Murine Ap2β1 Gene Causes Nonsyndromic Cleft Palate (2010) (19)
- Lysosomal protein trafficking in Giardia lamblia: common and distinct features. (2012) (19)
- Short protocols in cell biology : a compendium of methods from Current protocols in cell biology (2004) (18)
- Presence of an autoantibody against a Golgi cisternal membrane protein in the serum and cerebrospinal fluid from a patient with idiopathic late onset cerebellar ataxia (1988) (18)
- Regulation of LC3B levels by ubiquitination and proteasomal degradation (2019) (17)
- Formation of Tubulovesicular Carriers from Endosomes and Their Fusion to the trans-Golgi Network. (2015) (17)
- UNIT 10.16 Immunoprecipitation (2001) (16)
- Polarized trafficking of the sorting receptor SorLA in neurons and MDCK cells (2016) (16)
- Competition Model for Upregulation of the Major Histocompatibility Complex Class II-Associated Invariant Chain by Human Immunodeficiency Virus Type 1 Nef (2008) (16)
- Quality control of receptor-kinase signaling complexes. (2002) (15)
- Ggas (2000) (15)
- Reversible association with motor proteins (RAMP): A streptavidin-based method to manipulate organelle positioning (2019) (14)
- Imaging the Polarized Sorting of Proteins from the Golgi Complex in Live Neurons. (2016) (14)
- The ubiquitin isopeptidase USP10 deubiquitinates LC3B to increase LC3B levels and autophagic activity (2021) (13)
- The role of the zeta chain in the expression, structure and function of the T cell receptor. (1989) (13)
- Protein Labeling and Immunoprecipitation (2002) (13)
- UNIT 8.3 Immunoprecipitation (2001) (13)
- The FTS-Hook-FHIP (FHF) complex interacts with AP-4 to mediate perinuclear distribution of AP-4 and its cargo ATG9A (2020) (12)
- Formation of complexes between 125I-labelled human or bovine somatotropins and binding proteins in vivo in rat liver and kidney. (1983) (12)
- The T cell receptor-associated protein is proteolytically cleaved in a pre-Golgi compartment. (1990) (12)
- The Golgi-associated retrograde protein (GARP) complex plays an essential role in the maintenance of the Golgi glycosylation machinery (2020) (12)
- RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin (2022) (11)
- Cloning, expression, and localization of a novel gamma-adaptin-like molecule. (1998) (11)
- T cell antigen receptor: structure, assembly and function. (1989) (11)
- Disulfide Linkage of the ( and q Chains of the T Cell Receptor (1988) (11)
- Mutations in Auxilin cause parkinsonism via impaired clathrin-mediated trafficking at the Golgi apparatus and synapse (2019) (11)
- UNIT 9.8 Immunoprecipitation (2001) (10)
- Biosynthetic Labeling of Proteins (2001) (10)
- Chapter 4 Architectural Editing: Regulating the Surface Expression of the Multicomponent T-Cell Antigen Receptor (1990) (10)
- Electrophoresis and Immunoblotting (2002) (10)
- Solubilization of the lactogenic receptors from rat liver microsomes. (1978) (9)
- The autophagy protein ATG9A promotes HIV-1 infectivity (2019) (8)
- Cloning of the gene encoding the murine clathrin-associated adaptor medium chain mu 2: gene organization, alternative splicing and chromosomal assignment. (1998) (8)
- Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points (2017) (7)
- Human somatotropin binding to rabbit kidney microsomal fraction. (1981) (7)
- RUSC2 and WDR47 oppositely regulate kinesin–1-dependent distribution of ATG9A to the cell periphery (2021) (7)
- Metabolic Labeling with Amino Acids (1998) (6)
- Enthoprotin (2002) (6)
- Negative Regulation of Autophagy by UBA 6-BIRC 6 – Mediated Ubiquitination of LC 3 2 3 (6)
- Characterization Of Cellular Proteins (2000) (5)
- Distinct changes in endosomal composition promote NLRP3 inflammasome activation (2022) (5)
- The structure of human ATG9A and its interplay with the lipid bilayer (2020) (5)
- Immunoprecipitation (2001) (5)
- Staining Proteins in Gels (2000) (5)
- Loss of endocytosis-associated RabGEF1 causes aberrant morphogenesis and altered autophagy in photoreceptors leading to retinal degeneration (2020) (5)
- Properties of human growth hormone binding sites solubilized from female rabbit kidney. (1982) (5)
- Disorders of intracellular protein trafficking in human disease. (1995) (5)
- UNIT 7.2 Immunoprecipitation (2001) (5)
- A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1 (2021) (5)
- Immunoprecipitation (1999) (4)
- PI4P and BLOC-1 remodel endosomal membranes into tubules (2021) (4)
- 1 ASSEMBLY OF THE BIOGENESIS OF LYSOSOME-RELATED ORGANELLES COMPLEX-3 ( BLOC-3 ) AND ITS INTERACTION WITH RAB 9 (2009) (4)
- Defective endosome-TGN retrograde transport promotes NLRP3 inflammasome activation (2021) (4)
- Nef-arious goings-on at the Golgi (2012) (4)
- The T-cell antigen receptor: a complex signal-transducing molecule. (1988) (4)
- Subcellular Fractionation and Isolation of Organelles (2010) (3)
- Subcellular Fractionation and Isolation of Organelles (2005) (3)
- The Rab 5 Guanine Nucleotide Exchange Factor Rabex-5 Binds Ubiquitin and Functions as a Ubiquitin Ligase through an Atypical UIM and a Zinc Finger Domain (2005) (3)
- A widely distributed nuclear protein immunologically related to the microtubule-associated protein MAPI is associated with the mitotic spindle ( p 280 / cytoskeleton / centrioles / monoclonal antibodies ) (3)
- Going forward with retromer. (2014) (3)
- Correction: ARFRP1 functions upstream of ARL1 and ARL5 to coordinate recruitment of tethering factors to the trans-Golgi network (2019) (2)
- The role of AP-4 in cargo export from the trans-Golgi network and hereditary spastic paraplegia. (2020) (2)
- Transcytosis and trans-synaptic retention by postsynaptic ErbB4 underlie axonal accumulation of NRG3 (2022) (2)
- Adaptins □ D The Final Recount (2001) (2)
- Signal-binding Specificity of the m4 Subunit of the Adaptor Protein (2001) (2)
- Consecutive functions of small GTPases guide HOPS-mediated tethering of late endosomes and lysosomes (2023) (2)
- [Regulatory mechanisms of the clathrin adaptor molecules AP-1 and GGAs]. (2008) (1)
- Immunoprecipitation (2006) (1)
- RUFY3 and RUFY4 are ARL8 effectors that couple lysosomes to dynein-dynactin (2021) (1)
- Structural Characteristics of the Leydig Cell Lactogen Receptors (1984) (1)
- Conference Proceedings Eighth International Chorea–Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points (2017) (1)
- UNIT 5.24 Immunoprecipitation (2006) (1)
- Protein transport from the trans-Golgi network to endosomes (2008) (1)
- Effect of the incomplete separation of bound and free ligand on binding measurements. (1981) (1)
- Hermansky-Pudlak Syndrome (HPS) as a Genetically Heterogeneous Disease: Clinical, Molecular, and Cell Biological Aspects (1999) (1)
- Table 2, Yeast mutants defective in degradation of proteins retained in the ER (2002) (1)
- Novel Determinant of Binding to AP-2 Immunodeficiency Virus Type 1 Nef Is a A Diacidic Motif in Human (2012) (1)
- Crystal structure of adaptor protein complex 3 (AP-3) mu3A subunit C-terminal domain, in complex with a sorting peptide from TGN38 (2013) (1)
- Immunoprecipitation (1999) (1)
- Formation ofcomplexes between 1251-labelled humanorbovine somatotropins andbinding proteins invivo inratliver andkidney (1983) (0)
- Adaptins (AP-1, -2, -3, -4) (2002) (0)
- Preface (2012) (0)
- COMPLEX OF HUMAN GGA3 GAT DOMAIN AND UBIQUITIN (2005) (0)
- Interaction of HIV-1 Nef with the host protein Alix facilitates lysosomal targeting of CD4 (2014) (0)
- GARP-SNARE Interaction (2013) (0)
- Protein Trafficking (2010) (0)
- Protein Trafficking (2006) (0)
- Network to the Vacuole-Golgi trans Trafficking of ARN 1 from the Ubiquitin-dependent Steps in the Ubiquitin-independent and Gga 2 Mediates Sequential Developmental (2009) (0)
- Subcellular Fractionation and Isolation of Organelles (2010) (0)
- ReviewThe Mechanisms of Vesicle Budding and Fusion ganelles of the pathway (2004) (0)
- Subcellular Fractionation and Isolation of Organelles (2007) (0)
- Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1 (2016) (0)
- Subcellular Fractionation and Isolation of Organelles (2007) (0)
- Table of Contents (1991) (0)
- crystal structure of AP-2 alpha/simga2 complex bound to HIV-1 Nef (2014) (0)
- Getting where you want to go (2022) (0)
- Structure of retromer VPS26-VPS35 subunits bound to SNX3 and DMT1(L557M) (SeMet labeled) (2016) (0)
- Phagocytosis: Phagolysosome vesiculation promotes cell corpse degradation (2023) (0)
- The AP‐4 Complex Mediates Sorting and Processing of the Alzheimer's Disease Amyloid Precursor Protein (2009) (0)
- Subcellular Fractionation and Isolation of Organelles (2009) (0)
- Table 1, Proteins retained in the ER that are degraded by the proteasome (2002) (0)
- Crystal structure of human vps26 (2006) (0)
- A human iPSC-derived inducible neuronal model of Niemann-Pick disease, type C1 (2021) (0)
- GGA3 VHS domain complexed with C-terminal peptide from cation-independent mannose 6-phosphate receptor (2002) (0)
- Structure of VPS35 N terminal region (2016) (0)
- Subcellular Fractionation and Isolation of Organelles (2004) (0)
- Stem Cells (2005) (0)
- Immunoprecipitation (1998) (0)
- Intrathecal AAV9/AP4M1 gene therapy for hereditary spastic paraplegia 50 shows safety and efficacy in preclinical studies. (2023) (0)
- Author response: How HIV-1 Nef hijacks the AP-2 clathrin adaptor to downregulate CD4 (2013) (0)
- Body Pathway Protein Targets CD4 to the Multivesicular Human Immunodeficiency Virus Type 1 Nef (2014) (0)
- Two Cultures and the Revolution in Biotechnology (2004) (0)
- Figure 1, [The ubiquitin-proteasome pathway. The components...]. (2002) (0)
- C-terminal domain of Vps54 subunit of the GARP complex (2010) (0)
- A germline mutation in hepatocystin underlies autosomal dominant polycystic liver disease (2003) (0)
- Lysosome Positioning Influences mTORC2 and AKT Signaling-Jia and Bonifacino (2019) (0)
- The autophagy protein ATG9A promotes HIV-1 infectivity (2019) (0)
- Subcellular Fractionation and Isolation of Organelles (2008) (0)
- Table of Contents (1996) (0)
- Subcellular Fractionation and Isolation of Organelles (2006) (0)
- Novel Lysosomal Positioning Defects Due to Biallelic Mutations in BORCS7 Causes a Neurodegenerative Disease Presenting as Hereditary-Spastic Paraplegia (2021) (0)
- Subcellular Fractionation and Isolation of Organelles (2008) (0)
- CRYSTAL STRUCTURE OF GGA3 GAE DOMAIN IN COMPLEX WITH RABAPTIN-5 PEPTIDE (2003) (0)
- Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain D190A mutant, in complex with a sorting peptide from the amyloid precursor protein (APP) (2010) (0)
- The adaptor protein chaperone AAGAB stabilizes AP-4 complex subunits (2022) (0)
- Table 3, Transmembrane cell surface mammalian and yeast proteins that are subject to ubiquitination (2002) (0)
- Protein Trafficking (2007) (0)
- Subcellular Fractionation and Isolation of Organelles (2008) (0)
- Structure of retromer VPS26-VPS35 subunits bound to SNX3 (2016) (0)
- Digital imaging microscopy of living cells (1998) (0)
- Correction (1976) (0)
- Complex of GGA3-VHS Domain and CI-MPR C-terminal Phosphopeptide (2002) (0)
- Preface (2010) (0)
- Subcellular Fractionation and Isolation of Organelles (2009) (0)
- A neurodevelopmental disorder associated with an activating de novo missense variant in ARF1. (2022) (0)
- Vps54 C-terminal domain (2010) (0)
- Divalent interaction between HPS1 and HPS4 to form the Biogenesis of Lysosome‐related Organelles 3 (BLOC‐3) (2010) (0)
- Review for "An update on cellular and molecular determinants of Parkinson's disease with emphasis on the role of the retromer complex" (2020) (0)
- The Parkinson’s Disease P rotein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network (2020) (0)
- Invariant chain regulation of MHC class II function in the secretory and endocytic pathways (1997) (0)
- Lysosomes as dynamic regulators of cell and organismal homeostasis (2019) (0)
- Protein Trafficking (2004) (0)
- Autophagy-associated immune dysregulation and hyperplasia in a patient with compound heterozygous mutations in ATG9A (2022) (0)
- Preface (1998) (0)
- Introducing ESCRTs II and III (2011) (0)
- Stem Cells (2007) (0)
- melanosomes, and lysosomes contribute to the production and function of platelet dense granules, The Hermansky-Pudlak syndrome 1 (HPS1) and HPS2 genes independently (2012) (0)
- Metabolic Labeling with Amino Acids (1998) (0)
- Measurement of Lysosome Positioning by Shell Analysis and Line Scan. (2022) (0)
- Protein Trafficking (2006) (0)
- Protein Trafficking (2008) (0)
- Stem Cells (2007) (0)
- A Permeabilized CellSystemIdentifies the EndoplasmicReticulumasa SiteofProteinDegradation (1991) (0)
- Figure 2, [Schematic representation of the degradation...]. (2002) (0)
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