Jürgen Hescheler

Q: What Schools Are Affiliated With Jürgen Hescheler

Jürgen Hescheler is affiliated with the following schools: University of Vermont, Humboldt University of Berlin, University of Cologne, Free University of Berlin

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Why Is Jürgen Hescheler Influential?

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According to Wikipedia, Jürgen Karl-Josef Hescheler is a German physician and stem cell researcher. He is director to the Institute for Neurophysiology and a university professor at the University of Cologne. Hescheler has studied the biology of embryonic stem cells since the late 80's, and his publications have garnered an average total of over 1,000 citations per year since the late 2010's. He became the first researcher to accomplish an electrophysiological characterization of stem cells and was also among the first scientists in Germany obtaining permission to do research on human embryonic stem cells.. He is the founder and Chairman of the German Society for Stem Cell Research .

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Jürgen Hescheler's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Bone marrow–derived hematopoietic cells generate cardiomyocytes at a low frequency through cell fusion, but not transdifferentiation (2004) (1076)
Reactive Oxygen Species as Intracellular Messengers During Cell Growth and Differentiation (2001) (1057)
The GTP-binding protein, Go9 regulates neuronal calcium channels (1987) (839)
Monitoring of implanted stem cell migration in vivo: A highly resolved in vivo magnetic resonance imaging investigation of experimental stroke in rat (2002) (738)
Potential risks of bone marrow cell transplantation into infarcted hearts. (2007) (606)
cGMP-dependent protein kinase activates Ca-activated K channels in cerebral artery smooth muscle cells. (1993) (601)
Assignment of G-protein subtypes to specific receptors inducing inhibition of calcium currents (1991) (569)
Embryonic stem cells differentiate in vitro into cardiomyocytes representing sinusnodal, atrial and ventricular cell types (1993) (518)
Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents. (1994) (510)
Pluripotent mouse embryonic stem cells are able to differentiate into cardiomyocytes expressing chronotropic responses to adrenergic and cholinergic agents and Ca2+ channel blockers. (1991) (510)
Generation of Functional Murine Cardiac Myocytes From Induced Pluripotent Stem Cells (2008) (500)
Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart. (1991) (496)
Arterial dilations in response to calcitonin gene-related peptide involve activation of K+ channels (1990) (471)
Retinoic acid accelerates embryonic stem cell-derived cardiac differentiation and enhances development of ventricular cardiomyocytes. (1997) (449)
Differentiation of pluripotent embryonic stem cells into the neuronal lineage in vitro gives rise to mature inhibitory and excitatory neurons (1995) (405)
Embryonic stem cells: a model to study structural and functional properties in cardiomyogenesis. (1997) (395)
Muscle cell differentiation of embryonic stem cells reflects myogenesis in vivo: developmentally regulated expression of myogenic determination genes and functional expression of ionic currents. (1994) (395)
Injection of subunits of cyclic AMP-dependent protein kinase into cardiac myocytes modulates Ca2+ current (1982) (378)
Selectivity in signal transduction determined by gamma subunits of heterotrimeric G proteins. (1993) (376)
Regulation of cardiac L-type calcium current by phosphorylation and G proteins. (1990) (374)
Host-Dependent Tumorigenesis of Embryonic Stem Cell Transplantation in Experimental Stroke (2003) (373)
Different β-subunits determine G-protein interaction with transmembrane receptors (1992) (360)
Engraftment of engineered ES cell–derived cardiomyocytes but not BM cells restores contractile function to the infarcted myocardium (2006) (352)
Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals (2011) (323)
Selection of ventricular‐like cardiomyocytes from ES cells in vitro (2000) (307)
Regulation of the multidrug resistance transporter P‐glycoprotein in multicellular tumor spheroids by hypoxia‐inducible factor‐1 and reactive oxygen species (2003) (287)
Generation of pluripotent stem cells from adult human testis (2008) (279)
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. (2009) (279)
Cardiac specific differentiation of mouse embryonic stem cells. (2003) (251)
Generation of pluripotent stem cells from adult human testis (2009) (248)
Role of reactive oxygen species and phosphatidylinositol 3‐kinase in cardiomyocyte differentiation of embryonic stem cells (2000) (246)
Effective engraftment but poor mid-term persistence of mononuclear and mesenchymal bone marrow cells in acute and chronic rat myocardial infarction. (2006) (244)
Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin. (1996) (207)
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach (2012) (207)
Effects of electrical fields on cardiomyocyte differentiation of embryonic stem cells (1999) (204)
Estimation of Action Potential Changes from Field Potential Recordings in Multicellular Mouse Cardiac Myocyte Cultures (2003) (198)
In vitro Modeling of Ryanodine Receptor 2 Dysfunction Using Human Induced Pluripotent Stem Cells (2011) (196)
Functional Characteristics of ES Cell–derived Cardiac Precursor Cells Identified by Tissue-specific Expression of the Green Fluorescent Protein (1998) (193)
Tumor-induced angiogenesis studied in confrontation cultures of multicellular tumor spheroids and embryoid bodies grown from pluripotent embryonic stem cells. (2001) (179)
CPAP promotes timely cilium disassembly to maintain neural progenitor pool (2016) (164)
Chemoprotective mechanism of the natural compounds, epigallocatechin-3-O-gallate, quercetin and curcumin against cancer and cardiovascular diseases. (2009) (162)
Developmental changes in contractility and sarcomeric proteins from the early embryonic to the adult stage in the mouse heart (2003) (159)
Comparison of the Ca2 + currents induced by expression of three cloned α1 subunits, α1G, α1H and α1I, of low‐voltage‐activated T‐type Ca2 + channels (1999) (150)
Role of G proteins in calcium channel modulation. (1990) (149)
Cellular Cardiomyoplasty Improves Survival After Myocardial Injury (2002) (148)
Nitric oxide synthase expression and role during cardiomyogenesis. (1999) (144)
Mechanical strain-induced Ca(2+) waves are propagated via ATP release and purinergic receptor activation. (2000) (140)
Regulation of the cardiac calcium channel by protein phosphatases. (1987) (137)
The embryoid body as a novel in vitro assay system for antiangiogenic agents. (1998) (136)
Intracellular Ca2+ oscillations drive spontaneous contractions in cardiomyocytes during early development. (1999) (136)
Evidence for a P O2‐sensitive K+ channel in the type‐I cell of the rabbit carotid body (1989) (135)
Toxicogenomics directory of chemically exposed human hepatocytes (2014) (135)
Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro (2009) (132)
Control of voltage‐dependent Ca2+ channels by G protein‐coupled receptors (1988) (130)
In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities (2016) (124)
Embryonic stem cells: a promising tool for cell replacement therapy (2004) (124)
Development of electrical activity in cardiac myocyte aggregates derived from mouse embryonic stem cells. (2003) (123)
Angiotensin II‐induced stimulation of voltage‐dependent Ca2+ currents in an adrenal cortical cell line. (1988) (121)
Inward-rectifying channels in isolated patches of the heart cell membrane: ATP-dependence and comparison with cell-attached patches (1984) (120)
Identification and characterization of embryonic stem cell‐derived pacemaker and atrial cardiomyocytes (2005) (119)
“Run-down” of the Ca current during long whole-cell recordings in guinea pig heart cells: role of phosphorylation and intracellular calcium (1988) (115)
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing. (2010) (115)
Thalidomide inhibits angiogenesis in embryoid bodies by the generation of hydroxyl radicals. (2000) (114)
Establishment of beta-adrenergic modulation of L-type Ca2+ current in the early stages of cardiomyocyte development. (1999) (113)
Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells (2010) (111)
Down-regulation of Intrinsic P-glycoprotein Expression in Multicellular Prostate Tumor Spheroids by Reactive Oxygen Species* (2001) (109)
Embryonic stem cell transplantation after experimental traumatic brain injury dramatically improves neurological outcome, but may cause tumors. (2007) (107)
Ionic currents on type-I cells of the rabbit carotid body measured by voltage-clamp experiments and the effect of hypoxia (1989) (102)
Electrocorticographic and deep intracerebral EEG recording in mice using a telemetry system. (2005) (102)
Immunohistochemical Detection of α1E Voltage-gated Ca2+ Channel Isoforms in Cerebellum, INS-1 Cells, and Neuroendocrine Cells of the Digestive System (1999) (101)
The High Mobility Group Protein HMGA2: A Co-Regulator of Chromatin Structure and Pluripotency in Stem Cells? (2009) (101)
Beta-adrenergic and Muscarinic Modulation of Human Embryonic Stem Cell-derived Cardio-myocytes (2004) (100)
Functional Coupling between mGluR1 and Cav3.1 T-Type Calcium Channels Contributes to Parallel Fiber-Induced Fast Calcium Signaling within Purkinje Cell Dendritic Spines (2009) (100)
Design Principles of Concentration-Dependent Transcriptome Deviations in Drug-Exposed Differentiating Stem Cells (2014) (100)
Ca2+ signaling in human induced pluripotent stem cell-derived cardiomyocytes (iPS-CM) from normal and catecholaminergic polymorphic ventricular tachycardia (CPVT)-afflicted subjects. (2013) (99)
Organotypic slice culture from human adult ventricular myocardium. (2012) (98)
Regulation of the L‐type Ca2+ channel during cardiomyogenesis: switch from NO to adenylyl cyclase‐mediated inhibition (1999) (96)
Modulation of Ca current during the phosphorylation cycle in the guinea pig heart (1986) (96)
Disturbances in glucose-tolerance, insulin-release, and stress-induced hyperglycemia upon disruption of the Ca(v)2.3 (alpha 1E) subunit of voltage-gated Ca(2+) channels. (2002) (95)
Cardiac Myocytes Derived from Murine Reprogrammed Fibroblasts: Intact Hormonal Regulation, Cardiac Ion Channel Expression and Development of Contractility (2009) (93)
Microelectrode arrays: a new tool to measure embryonic heart activity. (2004) (93)
Adrenoceptor‐mediated changes of excitation and contraction in ventricular heart muscle from guinea‐pigs and rabbits. (1988) (93)
Redox control of angiogenic factors and CD31-positive vessel-like structures in mouse embryonic stem cells after direct current electrical field stimulation. (2005) (91)
Epigenetic changes and disturbed neural development in a human embryonic stem cell-based model relating to the fetal valproate syndrome. (2012) (89)
Global transcriptional profiles of beating clusters derived from human induced pluripotent stem cells and embryonic stem cells are highly similar (2010) (88)
Trauma-associated inflammatory response impairs embryonic stem cell survival and integration after implantation into injured rat brain. (2007) (88)
Contractile properties of early human embryonic stem cell-derived cardiomyocytes: beta-adrenergic stimulation induces positive chronotropy and lusitropy but not inotropy. (2012) (88)
Reactive oxygen species‐linked regulation of the multidrug resistance transporter P‐glycoprotein in Nox‐1 overexpressing prostate tumor spheroids (2005) (87)
Determination of electrical properties of ES cell-derived cardiomyocytes using MEAs. (2004) (87)
Cardiac specific expression of the green fluorescent protein during early murine embryonic development (1998) (86)
The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy. (2008) (86)
Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment (2015) (86)
Reconsidering pluripotency tests: do we still need teratoma assays? (2013) (85)
Phosphatidylinositol 3-Kinase-dependent Membrane Recruitment of Rac-1 and p47phox Is Critical for α-Platelet-derived Growth Factor Receptor-induced Production of Reactive Oxygen Species* (2008) (85)
Cyclic AMP‐independent, dual regulation of voltage‐dependent Ca2+ currents by LHRH and somatostatin in a pituitary cell line. (1988) (85)
Loss of Annexin A7 Leads to Alterations in Frequency-Induced Shortening of Isolated Murine Cardiomyocytes (2001) (84)
Identification of Thalidomide-Specific Transcriptomics and Proteomics Signatures during Differentiation of Human Embryonic Stem Cells (2012) (84)
Pain Perception in Mice Lacking the β3 Subunit of Voltage-activated Calcium Channels* (2002) (84)
Identification of Plateled-derived Growth Factor-BB as Cardiogenesis-Inducing Factor in Mouse Embryonic stem cells under Serum-free Conditions (2003) (83)
Involvement of reactive oxygen species in cardiotrophin-1-induced proliferation of cardiomyocytes differentiated from murine embryonic stem cells. (2004) (82)
On the mechanism of muscarinic inhibition of the cardiac Ca current (1986) (81)
Altered Seizure Susceptibility in Mice Lacking the Cav2.3 E‐type Ca2+ Channel (2006) (81)
The Disease-Specific Phenotype in Cardiomyocytes Derived from Induced Pluripotent Stem Cells of Two Long QT Syndrome Type 3 Patients (2013) (80)
Intracellular Ca2+ Oscillations, a Potential Pacemaking Mechanism in Early Embryonic Heart Cells (2007) (80)
The Antimalaria Agent Artemisinin Exerts Antiangiogenic Effects in Mouse Embryonic Stem Cell-Derived Embryoid Bodies (2003) (79)
Development of an intrinsic P‐glycoprotein‐mediated doxorubicin resistance in quiescent cell layers of large, multicellular prostate tumor spheroids (1998) (79)
Involvement of pertussis toxin-sensitive G-proteins in the hormonal inhibition of dihydropyridine-sensitive Ca2+ currents in an insulin-secreting cell line (RINm5F). (1991) (79)
Unique Metabolic Features of Stem Cells, Cardiomyocytes, and Their Progenitors (2014) (79)
Regulation of the multidrug resistance transporter P‐glycoprotein in multicellular prostate tumor spheroids by hyperthermia and reactive oxygen species (2005) (79)
Medium-chain fatty acids modulate myocardial function via a cardiac odorant receptor (2017) (78)
Inhibition of Tumor-Induced Angiogenesis and Matrix-Metalloproteinase Expression in Confrontation Cultures of Embryoid Bodies and Tumor Spheroids by Plant Ingredients Used in Traditional Chinese Medicine (2003) (78)
Hippocampal seizure resistance and reduced neuronal excitotoxicity in mice lacking the Cav2.3 E/R-type voltage-gated calcium channel. (2007) (77)
Nestin‐Specific Green Fluorescent Protein Expression in Embryonic Stem Cell‐Derived Neural Precursor Cells Used for Transplantation (2001) (77)
Ablation of Cav2.3 / E–type voltage–gated calcium channel results in cardiac arrhythmia and altered autonomic control within the murine cardiovascular system (2004) (76)
Mechanisms of the inhibitory effects of epigallocatechin‐3 gallate on platelet‐derived growth factor‐BB‐induced cell signaling and mitogenesis (2004) (76)
Gi2 and protein kinase C are required for thyrotropin-releasing hormone-induced stimulation of voltage-dependent Ca2+ channels in rat pituitary GH3 cells. (1993) (76)
Functional coupling between 'R-type' Ca2+ channels and insulin secretion in the insulinoma cell line INS-1. (2001) (74)
Anticonvulsant valproic acid inhibits cardiomyocyte differentiation of embryonic stem cells by increasing intracellular levels of reactive oxygen species. (2003) (74)
Local response of L‐type Ca2+ current to nitric oxide in frog ventricular myocytes (2001) (73)
Activation of p90RSK and growth stimulation of multicellular tumor spheroids are dependent on reactive oxygen species generated after purinergic receptor stimulation by ATP (2001) (73)
Electrophysiological Maturation and Integration of Murine Fetal Cardiomyocytes After Transplantation (2007) (72)
Establishment of an in vitro reporter gene assay for developmental cardiac toxicity. (2001) (72)
Activity of complex III of the mitochondrial electron transport chain is essential for early heart muscle cell differentiation (2004) (72)
MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes (2016) (71)
Ventricular Slices of Adult Mouse Hearts - a new Multicellular In Vitro Model for Electrophysiological Studies (2006) (70)
The electrocardiogram of human embryonic stem cell-derived cardiomyocytes. (2005) (70)
Effect of Cardioactive Drugs on Action Potential Generation and Propagation in Embryonic Stem Cell-Derived Cardiomyocytes (2007) (70)
Stem cell implantation in ischemic mouse heart: a high‐resolution magnetic resonance imaging investigation (2005) (69)
Functional expression and regulation of the hyperpolarization activated non‐selective cation current in embryonic stem cell‐derived cardiomyocytes (2000) (69)
Differentiation of green fluorescent protein-labeled embryonic stem cell-derived neural precursor cells into Thy-1-positive neurons and glia after transplantation into adult rat striatum. (2000) (68)
Epigallocatechin-3-O-Gallate Inhibits the Angiotensin II-Induced Adhesion Molecule Expression in Human Umbilical Vein Endothelial Cell Via Inhibition of MAPK Pathways (2007) (68)
Trapping of growth factors by catechins: a possible therapeutical target for prevention of proliferative diseases. (2005) (66)
Combining Hypoxia and Bioreactor Hydrodynamics Boosts Induced Pluripotent Stem Cell Differentiation Towards Cardiomyocytes (2014) (66)
The expression and regulation of depolarization-activated K+ channels in the insulin-secreting cell line INS-1 (2001) (66)
Development of Cardiomyocytes Expressing Cardiac‐Specific Genes, Action Potentials, and Ionic Channels during Embryonic Stem Cell‐Derived Cardiogenesis (1995) (65)
The FunGenES Database: A Genomics Resource for Mouse Embryonic Stem Cell Differentiation (2009) (64)
Action potential propagation failures in long-term recordings from embryonic stem cell-derived cardiomyocytes in tissue culture (1999) (64)
Global transcriptome analysis of murine embryonic stem cell-derived cardiomyocytes (2007) (64)
Modification of L‐type calcium current by intracellularly applied trypsin in guinea‐pig ventricular myocytes. (1988) (64)
In vitro Model for Assessing Arrhythmogenic Properties of Drugs Based on High-resolution Impedance Measurements (2012) (64)
Effects of a protein phosphatase inhibitor, okadaic acid, on membrane currents of isolated guinea-pig cardiac myocytes (1988) (63)
In vitro differentiation of embryonic stem cells into cardiomyocytes or skeletal muscle cells is specifically modulated by retinoic acid (2004) (63)
Inhibition of the platelet‐derived growth factor β‐receptor tyrosine‐phosphorylation and its downstream intracellular signal transduction pathway in rat and human vascular smooth muscle cells by different catechins (2002) (62)
Redox regulation of P‐glycoprotein‐mediated multidrug resistance in multicellular prostate tumor spheroids (2000) (62)
Mechanisms of β3‐adrenoceptor‐induced eNOS activation in right atrial and left ventricular human myocardium (2004) (61)
Expression and a role of functionally coupled P2Y receptors in human dendritic cells (1999) (60)
G protein interaction with K+ and Ca2+ channels. (1997) (60)
Serpin-6 Expression Protects Embryonic Stem Cells from Lysis by Antigen-Specific CTL1 (2007) (60)
Silencing of B Cell Receptor Signals in Human Naive B Cells (2002) (59)
The WNT receptor FZD7 contributes to self-renewal signaling of human embryonic stem cells (2008) (59)
G-proteins involved in the calcium channel signalling system (1993) (58)
Doxorubicin distribution in multicellular prostate cancer spheroids evaluated by confocal laser scanning microscopy and the "optical probe technique". (1998) (58)
Regulation of intrinsic prion protein by growth factors and TNF-alpha: the role of intracellular reactive oxygen species. (2003) (58)
Force Measurements of Human Embryonic Stem Cell‐Derived Cardiomyocytes in an In Vitro Transplantation Model (2007) (58)
Endostatin, the Proteolytic Fragment of Collagen XVIII, Induces Vasorelaxation (2006) (58)
Effect of different vitrification protocols for human ovarian tissue on reactive oxygen species and apoptosis. (2003) (58)
Growth Stimulation Versus Induction of Cell Quiescence by Hydrogen Peroxide in Prostate Tumor Spheroids Is Encoded by the Duration of the Ca2+ Response* (1999) (58)
Calcium sparks in human ventricular cardiomyocytes from patients with terminal heart failure. (2002) (57)
Novel potent inhibitor of receptor-activated nonselective cation currents in HL-60 cells. (1993) (57)
Development of a neural teratogenicity test based on human embryonic stem cells: response to retinoic acid exposure. (2011) (57)
Concise Review: Induced Pluripotent Stem Cells and Lineage Reprogramming: Prospects for Bone Regeneration (2011) (57)
Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor (2016) (56)
Single calcium channel currents of arterial smooth muscle at physiological calcium concentrations. (1992) (56)
The Cav2.3 voltage-gated calcium channel in epileptogenesis—Shedding new light on an enigmatic channel (2006) (56)
Characteristics of calcium sparks in cardiomyocytes derived from embryonic stem cells. (2001) (56)
Identification of differentially expressed genes involved in the formation of multicellular tumor spheroids by HT-29 colon carcinoma cells. (2007) (55)
Comparison of the Ca2 + currents induced by expression of three cloned alpha1 subunits, alpha1G, alpha1H and alpha1I, of low-voltage-activated T-type Ca2 + channels. (1999) (55)
New isoform of the neuronal Ca2+ channel α1E subunit in islets of Langerhans and kidney (1998) (55)
Comparison of necrosis in human ovarian tissue after conventional slow freezing or vitrification and transplantation in ovariectomized SCID mice. (2004) (55)
Formation of postsynaptic-like membranes during differentiation of embryonic stem cells in vitro. (1998) (54)
The SEURAT-1 approach towards animal free human safety assessment. (2015) (54)
Presynaptic ‘Cav2.3‐containing’ E‐type Ca2+ channels share dual roles during neurotransmitter release (2005) (53)
Perlecan is critical for heart stability. (2008) (53)
Identification of Small Signalling Molecules Promoting Cardiac-Specific Differentiation of Mouse Embryonic Stem Cells (2006) (52)
Induced pluripotent mesenchymal stromal cell clones retain donor-derived differences in DNA methylation profiles. (2013) (52)
Alternate Splicing in the Cytosolic II–III Loop and the Carboxy Terminus of Human E-type Voltage-Gated Ca2+ Channels: Electrophysiological Characterization of Isoforms (2002) (52)
Immunological Barriers to Embryonic Stem Cell-Derived Therapies (2008) (52)
Human Pluripotent Stem Cell-Derived Cardiomyocytes: Response to TTX and Lidocain Reveals Strong Cell to Cell Variability (2012) (52)
Rapid establishment of the European Bank for induced Pluripotent Stem Cells (EBiSC) - the Hot Start experience. (2017) (52)
Role of Natural‐Killer Group 2 Member D Ligands and Intercellular Adhesion Molecule 1 in Natural Killer Cell‐Mediated Lysis of Murine Embryonic Stem Cells and Embryonic Stem Cell‐Derived Cardiomyocytes (2009) (51)
Receptor‐mediated modulation of recombinant neuronal class E calcium channels (1997) (50)
Impact of human autoantibodies on β1-adrenergic receptor conformation, activity, and internalization (2012) (49)
yylncT Defines a Class of Divergently Transcribed lncRNAs and Safeguards the T-mediated Mesodermal Commitment of Human PSCs. (2019) (49)
Changes of membrane currents in cardiac cells induced by long whole-cell recordings and tolbutamide (1987) (49)
Does the organic calcium channel blocker D600 act from inside or outside on the cardiac cell membrane? (1982) (49)
Structural diversity of the voltage‐dependent Ca2+ channel α1E‐subunit (1998) (48)
Influence of endostatin on embryonic vasculo‐ and angiogenesis (2004) (48)
Establishment of Ionic Channels and Signalling Cascades in the Embryonic Stem Cell-Derived Primitive Endoderm and Cardiovascular System (1999) (48)
The isolated perfused bovine retina--a sensitive tool for pharmacological research on retinal function. (2005) (48)
Stem cell-derived systems in toxicology assessment. (2015) (47)
Arrhythmia in Isolated Prenatal Hearts after Ablation of the Cav2.3 (α1E) Subunit of Voltage-gated Ca2+ Channels (2004) (47)
Reactive oxygen species‐mediated regulation of eNOS and iNOS expression in multicellular prostate tumor spheroids (2003) (47)
Signaling molecules, transcription growth factors and other regulators revealed from in-vivo and in-vitro models for the regulation of cardiac development. (2015) (46)
Establishment and characterization of a mouse embryonic heart slice preparation. (2005) (45)
Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation. (2015) (45)
Zonisamide block of cloned human T-type voltage-gated calcium channels (2009) (45)
Inflammatory Microenvironment of Acute Myocardial Infarction Prevents Regeneration of Heart with Stem Cells Therapy. (2019) (44)
Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells (2018) (44)
A possible physiological role of the Ca-dependent protease calpain and its inhibitor calpastatin on the Ca current in guinea pig myocytes (1988) (44)
Differential Role of bFGF and VEGF for Vasculogenesis (2002) (43)
Direct current electrical fields induce apoptosis in oral mucosa cancer cells by NADPH oxidase‐derived reactive oxygen species (2008) (43)
Simulated Microgravity Modulates Differentiation Processes of Embryonic Stem Cells (2016) (43)
The use of quantitative image analysis in the assessment of in vitro embryotoxicity endpoints based on a novel embryonic stem cell clone with endoderm-related GFP expression. (2002) (43)
Redox-regulation of intrinsic prion expression in multicellular prostate tumor spheroids. (1999) (43)
Intracellular Ca 2 1 oscillations drive spontaneous contractions in cardiomyocytes during early development (1999) (43)
Temporospatial Relationships between Macroglia and Microglia during in vitro Differentiation of Murine Stem Cells (1998) (43)
Differential subunit composition of the G protein-activated inward-rectifier potassium channel during cardiac development. (2004) (42)
Embryonic stem-cell derived neurones express a maturation dependent pattern of voltage-gated calcium channels and calcium-binding proteins (2000) (42)
Cellular cardiomyoplasty in a transgenic mouse model. (2002) (42)
Inhibition of phosphatidylinositol-3-kinase blocks development of functional embryonic cardiomyocytes. (1999) (42)
Thyrotropin-releasing hormone induces opposite effects on Ca2+ channel currents in pituitary cells by two pathways. (1991) (42)
Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests (2016) (42)
Formyl peptides and ATP stimulate Ca2+ and Na+ inward currents through non-selective cation channels via G-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Involvement of Ca2+ and Na+ in the activation of beta-glucuronidase release and superoxide production. (1992) (41)
Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variations (2019) (41)
Electrophysiological integration and action potential properties of transplanted cardiomyocytes derived from induced pluripotent stem cells. (2013) (41)
The influence of physiological matrix conditions on permanent culture of induced pluripotent stem cell-derived cardiomyocytes. (2014) (41)
Modulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by cell cycle inhibitors. (2002) (41)
Human brain organoids assemble functionally integrated bilateral optic vesicles. (2021) (40)
Human and Murine Embryonic Stem Cell-Derived Cardiomyocytes Serve Together as a Valuable Model for Drug Safety Screening (2010) (40)
New isoform of the neuronal Ca2+ channel alpha1E subunit in islets of Langerhans and kidney--distribution of voltage-gated Ca2+ channel alpha1 subunits in cell lines and tissues. (1998) (40)
Effects of Cryopreservation on the Transcriptome of Human Embryonic Stem Cells After Thawing and Culturing (2011) (40)
Transcriptional responses to epigallocatechin‐3 gallate in HT 29 colon carcinoma spheroids (2004) (40)
Adult mesenchymal stromal stem cells for therapeutic applications (2008) (40)
Three LIF-dependent signatures and gene clusters with atypical expression profiles, identified by transcriptome studies in mouse ES cells and early derivatives (2009) (39)
Spironolactone Prevents Aldosterone Induced Increased Duration of Atrial Fibrillation in Rat (2012) (39)
Neuregulin-1β induces mature ventricular cardiac differentiation from induced pluripotent stem cells contributing to cardiac tissue repair. (2015) (39)
Properties of Ba2+ currents arising from human α1E and α1Eβ3 constructs expressed in HEK293 cells: physiology, pharmacology, and comparison to native T-type Ba2+ currents (1998) (39)
Spontaneous calcium oscillations in embryonic stem cell-derived primitive endodermal cells. (1998) (38)
Biological and Physicochemical Characterization of a Serum-and Xeno-Free Chemically Defined Cryopreservation Procedure for Adult Human Progenitor Cells (2011) (38)
β1 integrin deficiency impairs migration and differentiation of mouse embryonic stem cell derived neurons (1998) (37)
Fibroblasts facilitate the engraftment of embryonic stem cell-derived cardiomyocytes on three-dimensional collagen matrices and aggregation in hanging drops. (2010) (36)
Quantitation and functional characterization of neural cells derived from ES cells using nestin enhancer-mediated targeting in vitro. (2002) (36)
Cardiomyocytes facing fibrotic conditions re-express extracellular matrix transcripts. (2019) (36)
Ca2+‐sensitive regulation of E‐type Ca2+ channel activity depends on an arginine‐rich region in the cytosolic II–III loop (2003) (35)
Functional expression of the Na+/Ca2+ exchanger in the embryonic mouse heart. (2007) (35)
Altered thalamocortical rhythmicity in Cav2.3-deficient mice (2008) (34)
Impulse propagation in late-stage embryonic and neonatal murine ventricular slices. (2006) (34)
Gangliosides GM1 and GM2 Induce Vascular Smooth Muscle Cell Proliferation via Extracellular Signal-Regulated Kinase 1/2 Pathway (2001) (34)
Functional Characterization of Inward Rectifier Potassium Ion Channel in Murine Fetal Ventricular Cardiomyocytes (2010) (34)
Generation and Characterization of Functional Cardiomyocytes from Rhesus Monkey Embryonic Stem Cells (2006) (34)
Influence of Cell Treatment with PDGF-BB and Reperfusion on Cardiac Persistence of Mononuclear and Mesenchymal Bone Marrow Cells after Transplantation into Acute Myocardial Infarction in Rats (2009) (34)
Test systems of developmental toxicity: state-of-the art and future perspectives (2013) (33)
Effective surface-based cryopreservation of human embryonic stem cells by vitrification. (2011) (33)
The cytosolic II–III loop of Cav2.3 provides an essential determinant for the phorbol ester‐mediated stimulation of E–type Ca2+ channel activity (2004) (33)
Steady-state currents through voltage-dependent, dihydropyridine-sensitive Ca2+ channels in GH3 pituitary cells (1991) (33)
Susceptibility of murine induced pluripotent stem cell-derived cardiomyocytes to hypoxia and nutrient deprivation (2015) (33)
Development of G Protein‐mediated Ca2+ Channel Regulation in Mouse Embryonic Stem Cell‐derived Neurons (1997) (32)
diXa: a data infrastructure for chemical safety assessment (2014) (32)
S100A1 Enhances the L-type Ca2+ Current in Embryonic Mouse and Neonatal Rat Ventricular Cardiomyocytes* (2005) (32)
Heterotrimeric G Proteins Involved in the Modulation of Voltage‐dependent Calcium Channels of Neuroendocrine Cells a (1994) (32)
Nitric oxide synthase expression and function in embryonic and adult cardiomyocytes (2001) (32)
The ablation of the Ca(v)2.3/E-type voltage-gated Ca2+ channel causes a mild phenotype despite an altered glucose induced glucagon response in isolated islets of Langerhans. (2005) (32)
Insulin-like growth factor I modulates voltage-dependent Ca2+ channels in neuronal cells (1992) (32)
Calcium‐dependence of hydrogen peroxide‐induced c‐fos expression and growth stimulation of multicellular prostate tumor spheroids (1997) (31)
Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells (2016) (31)
The Molecular Chaperone hsp70 Interacts with the Cytosolic II-III Loop of the Cav2.3 E-type Voltagegated Ca2+ Channel (2006) (31)
The DC electrical-field-induced Ca(2+) response and growth stimulation of multicellular tumor spheroids are mediated by ATP release and purinergic receptor stimulation. (2002) (31)
Optimized Generation of Functional Neutrophils and Macrophages from Patient-Specific Induced Pluripotent Stem Cells: Ex Vivo Models of X0-Linked, AR220- and AR470- Chronic Granulomatous Diseases (2014) (31)
On the mechanism of histamine induced enhancement of the cardiac Ca2+ current (1987) (31)
A lncRNA Perspective into (Re)Building the Heart (2016) (31)
An optimized embryonic stem cell model for consistent gene expression and developmental studies (2005) (31)
Human Embryonic and Induced Pluripotent Stem Cell Based Toxicity Testing Models: Future Applications in New Drug Discovery. (2016) (30)
Complex Clearance Mechanisms After Intraventricular Hemorrhage and rt-PA Treatment—a Review on Clinical Trials (2019) (30)
Neuronal developmental gene and miRNA signatures induced by histone deacetylase inhibitors in human embryonic stem cells (2015) (30)
Nonselective cation channels: physiological and pharmacological modulations of channel activity. (1993) (30)
Regulation of the Na+/Ca2+ exchanger (NCX) in the murine embryonic heart. (2007) (30)
Disruption of cytoskeletal integrity impairs Gi-mediated signaling due to displacement of Gi proteins (2001) (30)
Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex. (2018) (29)
Initial Colony Morphology-Based Selection for iPS Cells Derived from Adult Fibroblasts Is Substantially Improved by Temporary UTF1-Based Selection (2010) (29)
Retracted: Cav2.3 (R‐type) calcium channels are critical for mediating anticonvulsive and neuroprotective properties of lamotrigine in vivo (2013) (29)
Bioluminescent Imaging of Genetically Selected Induced Pluripotent Stem Cell-Derived Cardiomyocytes after Transplantation into Infarcted Heart of Syngeneic Recipients (2014) (29)
Cav2.3 (R-Type) Calcium Channels are Critical for Mediating Anticonvulsive and Neuroprotective Properties of Lamotrigine In Vivo (2017) (29)
Metabolite signatures of doxorubicin induced toxicity in human induced pluripotent stem cell-derived cardiomyocytes (2017) (29)
Phosphatidylinositol 3-kinase-dependent membrane recruitment of Rac-1 and p47phox is critical for alpha-platelet-derived growth factor receptor-induced production of reactive oxygen species. (2008) (28)
Inhibition of Ca2+ channels via alpha 2-adrenergic and muscarinic receptors in pheochromocytoma (PC-12) cells. (1991) (28)
Developmental changes in functional expression and β-adrenergic regulation of If in the heart of mouse embryo (2002) (28)
Voltage-gated calcium channels: Determinants of channel function and modulation by inorganic cations (2015) (28)
Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes (2017) (28)
Lack of Laminin γ1 in Embryonic Stem Cell‐Derived Cardiomyocytes Causes Inhomogeneous Electrical Spreading Despite Intact Differentiation and Function (2009) (27)
Electrophysiological and Morphological Maturation of Murine Fetal Cardiomyocytes During Electrical Stimulation In Vitro (2015) (27)
The protein-specific phosphatase 1 antagonizes the β-adrenergic increase of the cardiac Ca current (1986) (27)
Regionally diverse mitochondrial calcium signaling regulates spontaneous pacing in developing cardiomyocytes. (2015) (27)
Embryonic stem cells produce neurotrophins in response to cerebral tissue extract: Cell line‐dependent differences (2007) (27)
Ascorbic Acid-Induced Cardiac Differentiation of Murine Pluripotent Stem Cells: Transcriptional Profiling and Effect of a Small Molecule Synergist of Wnt/β-Catenin Signaling Pathway (2015) (27)
Neonatal Murine Heart Slices. A Robust Model to Study Ventricular Isometric Contractions (2007) (26)
“The Good into the Pot, the Bad into the Crop!”—A New Technology to Free Stem Cells from Feeder Cells (2008) (26)
Entrapment of Embryonic Stem Cells-Derived Cardiomyocytes in Macroporous Biodegradable Microspheres: Preparation and Characterization (2008) (26)
Reduction of insulin secretion in the insulinoma cell line INS-1 by overexpression of a Ca(v)2.3 (alpha1E) calcium channel antisense cassette. (2002) (26)
Functional Characterization and Transcriptome Analysis of Embryonic Stem Cell–Derived Contractile Smooth Muscle Cells (2009) (25)
Endostatin influences endothelial morphology via the activated ERK1/2-kinase endothelial morphology and signal transduction. (2006) (25)
Embryonic stem cells for basic research and potential clinical applications in cardiology. (2005) (25)
Transcriptomic and phenotypic analysis of murine embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning (2007) (25)
Role of ATP-dependent K(+) channels in the electrical excitability of early embryonic stem cell-derived cardiomyocytes. (1999) (24)
Traditional Chinese Medicine Baicalin Suppresses mESCs Proliferation through Inhibition of miR-294 Expression (2015) (24)
Inhibition of voltage-dependent Ca2+ currents and activation of pertussis toxin-sensitive G-proteins via muscarinic receptors in GH3 cells. (1991) (24)
Skeletal Extracellular Matrix Supports Cardiac Differentiation of Embryonic Stem Cells: a Potential Scaffold for Engineered Cardiac Tissue (2018) (23)
Inhibition of voltage-dependent Ca2+ channels via α2-adrenergic and opioid receptors in cultured bovine adrenal chromaffin cells (1992) (23)
Embryonic stem cells as a model for the physiological analysis of the cardiovascular system. (2002) (23)
Neural Differentiation of Embryonic Stem Cells is Induced by Signalling from Non-Neural Niche Cells (2006) (23)
Nitric oxide, a key signaling molecule in the murine early embryonic heart (2004) (23)
Low-Dose Lithium Stabilizes Human Endothelial Barrier by Decreasing MLC Phosphorylation and Universally Augments Cholinergic Vasorelaxation Capacity in a Direct Manner (2016) (23)
Measurement of apoptosis in long-term cultures of human ovarian tissue. (2001) (23)
Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC (2017) (23)
Mesenchymal stem cells-seeded bio-ceramic construct for bone regeneration in large critical-size bone defect in rabbit (2016) (23)
Stimulation of single L‐type calcium channels in rat pituitary GH3 cells by thyrotropin‐releasing hormone. (1995) (22)
Protein and mRNA expression of serum and glucocorticoid‐dependent kinase 1 in metanephrogenesis (2001) (22)
In vitro differentiation of embryonic stem cells into cardiomyocytes or skeletal muscle cells is specifically modulated by retinoic acid (1994) (22)
Extract Derived from Rat Brains in the Acute Phase Following Traumatic Brain Injury Impairs Survival of Undifferentiated Stem Cells and Induces Rapid Differentiation of Surviving Cells (2011) (22)
The L-type Ca2+ Channels Blocker Nifedipine Represses Mesodermal Fate Determination in Murine Embryonic Stem Cells (2013) (22)
Establishment and Characterization of a Mouse Embryonic Heart Slice Preparation (2005) (22)
Gene expression signatures defining fundamental biological processes in pluripotent, early, and late differentiated embryonic stem cells. (2012) (22)
Loss of genomic integrity induced by lysosphingolipid imbalance drives ageing in the heart (2019) (21)
Characterisation of cholinesterase expression during murine embryonic stem cell differentiation. (2008) (21)
Integration Properties of Wharton’s Jelly-derived Novel Mesenchymal Stem Cells into Ventricular Slices of Murine Hearts (2011) (20)
Puerarin Facilitates T-Tubule Development of Murine Embryonic Stem Cell-Derived Cardiomyocytes (2014) (20)
Mu-Opioid Receptor mRNA Regulation During Morphine Tolerance in the Rat Peripheral Nervous System (2003) (20)
The Electrophysiology of Neuroendocrine Cells (1995) (20)
Specific Gene Signatures and Pathways in Mesodermal Cells and Their Derivatives Derived from Embryonic Stem Cells (2012) (20)
Biological pacemakers: characterization in an in vitro coculture model. (2008) (20)
DC electrical field-induced c-fos expression and growth stimulation in multicellular prostate cancer spheroids. (1997) (20)
Electrical fields enhance growth of cancer spheroids by reactive oxygen species and intracellular Ca2+. (1997) (20)
Hypotonic Ca2+ signaling and volume regulation in proliferating and quiescent cells from multicellular spheroids (1998) (19)
Antagonists of ionotropic γ‐aminobutyric acid receptors impair the NiCl2‐mediated stimulation of the electroretinogram b‐wave amplitude from the isolated superfused vertebrate retina (2009) (19)
Regulation of Na+/Ca2+ Exchange Current in the Normal and Failing Heart (2007) (19)
Induced Pluripotent Stem Cells: A New Approach for Physiological Research (2006) (19)
Fam40b is required for lineage commitment of murine embryonic stem cells (2014) (19)
Pharmacoresistant Cav2·3 (E‐type/R‐type) voltage‐gated calcium channels influence heart rate dynamics and may contribute to cardiac impulse conduction (2013) (18)
Scalable Selection of Hepatocyte‐ and Hepatocyte Precursor‐Like Cells from Culture of Differentiating Transgenically Modified Murine Embryonic Stem Cells (2008) (18)
Transcriptomics of Hepatocytes Treated with Toxicants for Investigating Molecular Mechanisms Underlying Hepatotoxicity. (2015) (18)
Indispensable tools: embryonic stem cells yield insights into the human heart. (2001) (18)
Developmental Potential of the Murine Embryonic Stem Cells Transplanted into the Healthy Rat Brain - Novel Insights into Tumorigenesis (2009) (18)
Electrophysiological Characteristics of Embryonic Stem Cell-Derived Cardiomyocytes are Cell Line-Dependent (2015) (18)
A differential impact of lithium on endothelium-dependent but not on endothelium-independent vessel relaxation (2016) (18)
A Ni2+-sensitive component of the ERG b-wave from the isolated bovine retina is related to E-type voltage-gated Ca2+ channels (2005) (18)
Physiological Differences Between Transplanted and Host Tissue Cause Functional Decoupling after in vitro Transplantation of Human Embryonic Stem Cell-Derived Cardiomyocytes (2009) (18)
Transcriptional profiling of CD31+ cells isolated from murine embryonic stem cells (2009) (17)
Ras proteins activate calcium channels in neuronal cells. (1991) (17)
Increased doxorubicin uptake and toxicity in multicellular tumour spheroids treated with DC electrical fields (1999) (17)
All-trans retinoic acid and basic fibroblast growth factor synergistically direct pluripotent human embryonic stem cells to extraembryonic lineages. (2013) (17)
Modulation of L-type Ca2+ channel current density and inactivation by β-adrenergic stimulation during murine cardiac embryogenesis (2009) (17)
Effects of spermine NONOate and ATP on protein aggregation: light scattering evidences (2013) (17)
Atropine-sensitive hippocampal theta oscillations are mediated by Cav2.3 R-type Ca2+ channels (2012) (17)
Outwards currents in embryonic stem cell-derived cardiomyocytes (2000) (17)
In vitro differentiation of murine embryonic stem cells into keratinocyte-like cells. (2007) (17)
Effects of phosphodiesterase type 5 inhibitor sildenafil on retinal function in isolated superfused retina. (2005) (17)
The aging heart: changes in the pharmacodynamic electrophysiological response to verapamil in aged rabbit hearts. (2010) (16)
Puerarin Suppresses the Self-Renewal of Murine Embryonic Stem Cells by Inhibition of REST-MiR-21 Regulatory Pathway (2015) (16)
Generation and characterization of cardiomyocytes under serum-free conditions. (2006) (16)
Structural diversity of the voltage-dependent Ca2+ channel alpha1E-subunit. (1998) (16)
Effect of ZnCl2 and Chelation of Zinc Ions by N,N-Diethyldithiocarbamate (DEDTC) on the ERG b-Wave Amplitude from the Isolated Superfused Vertebrate Retina (2010) (16)
CD3× anti‐nitrophenyl bispecific diabodies: Universal immunotherapeutic tools for retargeting T cells to tumors (1999) (16)
Two separate Ni2+-sensitive voltage-gated Ca2+channels modulate transretinal signalling in the isolated murine retina (2011) (16)
Adenylyl cyclase/cAMP-PKA-mediated phosphorylation of basal L-type Ca(2+) channels in mouse embryonic ventricular myocytes. (2011) (15)
Direct contact of umbilical cord blood endothelial progenitors with living cardiac tissue is a requirement for vascular tube-like structures formation (2011) (15)
Pitfalls and fallacies interfering with correct identification of embryonic stem cells implanted into the brain after experimental traumatic injury (2013) (15)
ESNATS Conference — The use of Human Embryonic Stem Cells for Novel Toxicity Testing Approaches a (2014) (15)
How “Pharmacoresistant” is Cav2.3, the Major Component of Voltage-Gated R-type Ca2+ Channels? (2013) (15)
Isolation and Functional Characterization of α-Smooth Muscle Actin Expressing Cardiomyocytes from Embryonic Stem Cells (2006) (15)
Chemically Induced Cardiomyogenesis of Mouse Embryonic Stem Cells (2010) (15)
Dietary small molecules and large-scale gene expression studies: an experimental approach for understanding their beneficial effects on the development of malignant and non-malignant proliferative diseases. (2006) (15)
A chemical genetics approach for specific differentiation of stem cells to somatic cells: a new promising therapeutical approach. (2008) (15)
Mesenchymal stem cells and their conditioned medium improve integration of purified induced pluripotent stem cell-derived cardiomyocyte clusters into myocardial tissue. (2014) (15)
Fibroblasts support functional integration of purified embryonic stem cell-derived cardiomyocytes into avital myocardial tissue. (2011) (15)
Beta1 integrin deficiency impairs migration and differentiation of mouse embryonic stem cell derived neurons. (1998) (14)
Surgical Approaches in Psychiatry: A Survey of the World Literature on Psychosurgery. (2017) (14)
Generation of Cardiomyocytes from Embryonic Stem Cells (2002) (14)
Isoforms of alpha1E voltage-gated calcium channels in rat cerebellar granule cells--detection of major calcium channel alpha1-transcripts by reverse transcription-polymerase chain reaction. (1999) (14)
Generation of cardiomyocytes from embryonic stem cells experimental studies. (2002) (14)
Molecular mechanisms of somatostatin's inhibition of hormone release: participation of voltage-gated calcium channels and G-proteins. (1993) (14)
Time-course of the electrophysiological maturation and integration of transplanted cardiomyocytes. (2012) (14)
Fusion and regenerative therapies: is immortality really recessive? (2007) (14)
Pharmacological Neuroenhancement: Current Aspects of Categorization, Epidemiology, Pharmacology, Drug Development, Ethics, and Future Perspectives (2021) (14)
STRIP2 Is Indispensable for the Onset of Embryonic Stem Cell Differentiation (2017) (14)
A Ni(2+)-sensitive component of the ERG b-wave from the isolated bovine retina is related to E-type voltage-gated Ca(2+) channels. (2005) (14)
Following the adverse outcome pathway from micronucleus to cancer using H2B-eGFP transgenic healthy stem cells (2020) (13)
Electrical Activity and Calcium Channels in Neuroendocrine Cells (1994) (13)
Current status of human pluripotent stem cell based in vitro toxicity tests. (2013) (13)
Modulation of Differentiation Processes in Murine Embryonic Stem Cells Exposed to Parabolic Flight-Induced Acute Hypergravity and Microgravity (2018) (13)
Human brain organoids assemble functionally integrated bilateral optic vesicles (2021) (13)
Stem cells and their potential relevance to paediatric cardiology (2006) (13)
Cardiac phenomena during kainic-acid induced epilepsy and lamotrigine antiepileptic therapy (2014) (13)
Muscarinic cholinergic regulation of L-type calcium channel in heart of embryonic mice at different developmental stages. (2004) (13)
Generation of human induced pluripotent stem cell line from a patient with a long QT syndrome type 2. (2016) (13)
Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca2+ release channel (2016) (13)
Human ES cell derived cardiomyocytes for cell replacement therapy: a current update. (2008) (13)
Involvement of the guanine nucleotide-binding protein, No, in the inhibitory regulation of neuronal calcium channels. (1988) (12)
A comparative transcriptomic study on the effects of valproic acid on two different hESCs lines in a neural teratogenicity test system. (2014) (12)
Gadolinium enhancement in newly diagnosed patients with lumbar disc herniations are associated with inflammatory peridiscal tissue reactions – Evidence of fragment degradation? (2014) (12)
Regulation of Mitogen-Activated Protein Kinase Cascades by Low Density Lipoprotein and Lysophosphatidic Acid (2004) (12)
The Interaction between Adult Cardiac Fibroblasts and Embryonic Stem Cell-Derived Cardiomyocytes Leads to Proarrhythmic Changes in In Vitro Cocultures (2016) (12)
Electrophysiological properties of rat calcitonin-secreting cells (1991) (12)
Pertussis toxin-sensitive G-proteins: participation in the modulation of voltage-dependent Ca2+ channels by hormones and neurotransmitters. (1990) (12)
A slowly inactivating calcium current works as a calcium sensor in calcitonin‐secreting cells (1990) (12)
Integrins and cell structure: powerful determinants of heart development and heart function. (2000) (12)
Embryonic Stem Cells Facilitate the Isolation of Persistent Clonal Cardiovascular Progenitor Cell Lines and Leukemia Inhibitor Factor Maintains Their Self-Renewal and Myocardial Differentiation Potential in vitro (2013) (12)
From Early Embryonic to Adult Stage: Comparative Study of Action Potentials of Native and Pluripotent Stem Cell-Derived Cardiomyocytes. (2016) (12)
Cav2.3 Ca2+ Channel Interacts with the G1-subunit of V-ATPase (2011) (12)
Epigallocatechin-3-Gallate (EGCG): A Structural Target for the Development of Potential Therapeutic Drugs Against Anti-Proliferative Diseases (2005) (12)
Functional Expression and Regulation of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels (HCN) in Mouse iPS Cell-derived Cardiomyocytes after UTF1-Neo Selection (2014) (12)
Differentiation and Selection of Hepatocyte Precursors in Suspension Spheroid Culture of Transgenic Murine Embryonic Stem Cells (2012) (12)
Functional Expression and Inactivation of L-type Ca2+ Currents During Murine Heart Development -Implications for Cardiac Ca2+ Homeostasis (2007) (12)
Effects of Puerarin on Cardiac Differentiation and Ventricular Specialization of Murine Embryonic Stem Cells (2013) (11)
Electrophysiological Basis of the First Heart Beats (2006) (11)
Atrial Natriuretic Peptide Regulates Ca2+ Channel in Early Developmental Cardiomyocytes (2010) (11)
35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
Molecular and functional changes in voltage-gated Na⁺ channels in cardiomyocytes during mouse embryogenesis. (2011) (11)
Excitation-Contraction Coupling in Zebrafish Ventricular Myocardium Is Regulated by Trans-Sarcolemmal Ca2+ Influx and Sarcoplasmic Reticulum Ca2+ Release (2015) (11)
Parallel Genome-wide Profiling of Coding and Non-coding RNAs to Identify Novel Regulatory Elements in Embryonic and Maturated Heart (2018) (11)
The Effect of Antiarrhythmic Drugs on the Beat Rate Variability of Human Embryonic and Human Induced Pluripotent Stem Cell Derived Cardiomyocytes (2019) (11)
CD 30 is a marker of undifferentiated human embryonic stem cells rather than a biomarker of transformed hESCs (2008) (11)
Membrane potential dependent modulations of calcium oscillations in insulin-secreting INS-1 cells. (2002) (10)
In vitro chronotropic effects of Erythrina senegalensis DC (Fabaceae) aqueous extract on mouse heart slice and pluripotent stem cell-derived cardiomyocytes. (2015) (10)
Inversion of Ca2+ current modulation during recovery of neuroblastoma cells from pertussis toxin pretreatment (1993) (10)
Application of Stem Cell Technologies to Regenerate Injured Myocardium and Improve Cardiac Function. (2019) (10)
Receptor- and G-protein-mediated modulations of voltage-dependent calcium channels. (1988) (10)
Effects of Synthetic Neural Adhesion Molecule Mimetic Peptides and Related Proteins on the Cardiomyogenic Differentiation of Mouse Embryonic Stem Cells (2015) (10)
Preconditioning of skeletal myoblast-based engineered tissue constructs enables functional coupling to myocardium in vivo. (2015) (10)
Confrontation cultures of embryonic stem cells with multicellular tumor spheroids to study tumor-induced angiogenesis. (2006) (10)
Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis (2018) (10)
Distinct transcriptomic changes in E14.5 mouse skeletal muscle lacking RYR1 or Cav1.1 converge at E18.5 (2018) (9)
Hypoxia influences generation and propagation of electrical activity in embryonic cardiomyocyte clusters. (2002) (9)
Regulation of voltage-dependent Ca2+ channels in the early developing heart: role of β1 integrins (2002) (9)
Evidence for a Critical Role of Catecholamines for Cardiomyocyte Lineage Commitment in Murine Embryonic Stem Cells (2013) (9)
Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells (2020) (9)
Reciprocal modulation of Cav2.3 voltage‐gated calcium channels by copper(II) ions and kainic acid (2018) (9)
Are Catechins Natural Tyrosine Kinase Inhibitors? (2002) (9)
Action of beta-amyloid peptide₁₋₄₀ on I(HVA) and its modulation by ginkgolide B. (2006) (9)
Baicalin Maintains Late-Stage Functional Cardiomyocytes in Embryoid Bodies Derived from Murine Embryonic Stem Cells (2013) (9)
Effect of high-intensity irradiation from dental photopolymerization on the isolated and superfused vertebrate retina (2013) (9)
Electroretinographic Assessment of Inner Retinal Signaling in the Isolated and Superfused Murine Retina (2017) (8)
A practical guide to the preparation and use of metal ion‐buffered systems for physiological research (2018) (8)
[Ca2+] oscillations in a model of energy-dependent Ca2+ uptake by the endoplasmic reticulum. (2005) (8)
Cav3.2 T-Type Calcium Channels Are Physiologically Mandatory for the Auditory System (2019) (8)
Modulation of Cav2.3 channels by unconjugated bilirubin (UCB) – Candidate mechanism for UCB-induced neuromodulation and neurotoxicity (2019) (8)
Acute molecular effects of pressure‐controlled intermittent coronary sinus occlusion in patients with advanced heart failure (2018) (8)
Beat Rate Variability in Murine Embryonic Stem Cell-Derived Cardiomyocytes: Effect of Antiarrhythmic Drugs (2016) (8)
Inhibition of Ca(2+)-induced calcitonin secretion by somatostatin: roles of voltage dependent Ca2+ channels and G-proteins. (1992) (8)
Calcium Imaging in Pluripotent Stem Cell-Derived Cardiac Myocytes. (2016) (8)
Evidence for self-maintaining pluripotent murine stem cells in embryoid bodies (2014) (8)
Adenosine A1-receptors inhibit cAMP and Ca2+ mediated calcitonin secretion in C-cells. (1995) (8)
Stem cells and nuclear reprogramming (2008) (8)
APLP1 and Rab5A Interact with the II-III loop of the Voltage-gated Ca2+-channel Cav2.3 and Modulate its Internalization Differently (2011) (7)
Voltage-dependent L-type Ca channels and a novel type of non-selective cation channel activated by cAMP-dependent phosphorylation in mesoderm-like (MES-1) cells. (1993) (7)
Hyposmotic challenge modulates function of L-type calcium channel in rat ventricular myocytes through protein kinase C (2010) (7)
Cardiac differentiation of mesenchymal stem cells in sex mis-matched transplanted hearts: self-repair or just a visit? (2002) (7)
Diethyldithiocarbamate-mediated zinc ion chelation reveals role of Cav2.3 channels in glucagon secretion. (2015) (7)
Effect of hypoxia on hyperpolarization-activated current in mouse dorsal root ganglion neurons (2006) (7)
Somitovasculin, a Novel Endothelial-Specific Transcript Involved in the Vasculature Development (2009) (7)
Docosahexaenoic acid alters Gsα localization in lipid raft and potentiates adenylate cyclase. (2015) (7)
Regulation and function of ATP-dependent K+ channels in pancreatic B cells. (1989) (7)
Searching for reputability: first randomised study on bone-marrow transplantation in the heart (2004) (7)
Global transcriptomic analysis of murine embryonic stem cell‐derived brachyury+ (T) cells (2010) (7)
Effect of chemopreventive agents on differentiation of mouse embryonic stem cells. (2012) (7)
Steady-state Ca2+ influx and electrical activity in endocrine cells (1992) (7)
Cell persistence and electrical integration of transplanted fetal cardiomyocytes from different developmental stages. (2014) (7)
hESC Technology for Toxicology and Drug Development: Summary of Current Status and Recommendations for Best Practice and Standardization The Report and Recommendations of and ECVAM Workshop. (2007) (7)
Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment (2015) (7)
Cav2.3 R-type calcium channels: from its discovery to pathogenic de novo CACNA1E variants: a historical perspective (2020) (7)
The proliferative and chronotropic effects of Brillantaisia nitens Lindau (Acanthaceae) extracts on pluripotent stem cells and their cardiomyocytes derivatives. (2014) (7)
Intramyocardially Transplanted Neonatal Cardiomyocytes (NCMs) Show Structural and Electrophysiological Maturation and Integration and Dose-Dependently Stabilize Function of Infarcted Rat Hearts (2017) (7)
Modulation of miRNAs by natural agents: Nature’s way of dealing with cancer (2015) (7)
Effects of Embryotoxic Chemicals on the In vitro Differentiation of Genetically Engineered Embryonic Stem Cells into Cardiac Cells. (1999) (7)
Parabolic, Flight-Induced, Acute Hypergravity and Microgravity Effects on the Beating Rate of Human Cardiomyocytes (2019) (7)
Role of transient receptor potential vanilloid 4 in the effect of osmotic pressure on myocardial contractility in rat. (2008) (6)
Whole-cell clamp analysis for G-protein regulation of channels. (1994) (6)
The influence of dexamethasone administration on the protection against doxorubicin-induced cardiotoxicity in purified embryonic stem cell-derived cardiomyocytes. (2013) (6)
Functional Characterization and Gene Expression Profiling of α-Smooth Muscle Actin Expressing Cardiomyocytes Derived from Murine Induced Pluripotent Stem Cells (2012) (6)
Spotlight on stem cells--makes old hearts fresh. (2003) (6)
In vitro cellular models for cardiac development and pharmacotoxicology. (1995) (6)
In Vitro Grown Micro-Tissues for Cardiac Cell Replacement Therapy in Vivo. (2019) (6)
Pipette-based Method to Study Embryoid Body Formation Derived from Mouse and Human Pluripotent Stem Cells Partially Recapitulating Early Embryonic Development Under Simulated Microgravity Conditions (2016) (6)
Murine transgenic iPS cell line for monitoring and selection of cardiomyocytes. (2016) (6)
The C-terminus of human Ca(v)2.3 voltage-gated calcium channel interacts with alternatively spliced calmodulin-2 expressed in two human cell lines. (2012) (6)
From state-of-the-art cell therapy to endogenous cardiac repair. (2017) (6)
Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives (2017) (6)
Stem cell migration after stroke observed by in vivo MR imaging (2004) (6)
Coculture of Embryonic Ventricular Myocytes and Mouse Embryonic Stem Cell Enhance Intercellular Signaling by Upregulation of Connexin43 (2013) (6)
The dihydropyridine isradipine inhibits the murine but not the bovine a‐wave response of the electroretinogram (2008) (6)
Retraction: Generation of pluripotent stem cells from adult human testis (2009) (6)
Intracerebral Administration of Heat-Inactivated Staphylococcus Epidermidis Enhances Oncolysis and Prolongs Survival in a 9L Orthotopic Gliosarcoma Model (2013) (6)
Puerarin Enhances Ca2+ Reuptake and Ca2+ Content of Sarcoplasmic Reticulum in Murine Embryonic Stem Cell-Derived Cardiomyocytes via Upregulation of SERCA2a (2017) (5)
In vitro and in vivo phosphorylation of the Cav2.3 voltage-gated R-type calcium channel (2018) (5)
First steps towards the successful surface-based cultivation of human embryonic stem cells in hanging drop systems (2012) (5)
Properties and functions of KATP during mouse perinatal development. (2012) (5)
Cardiac functions of voltage-gated Ca(2+) channels: role of the pharmacoresistant type (E-/R-Type) in cardiac modulation and putative implication in sudden unexpected death in epilepsy (SUDEP). (2014) (5)
Puerarin Exerts a Delayed Inhibitory Effect on the Proliferation of Cardiomyocytes Derived from Murine ES Cells via Slowing Progression through G2/M Phase (2016) (5)
CHAPTER 16 – Receptor—Ion Channel Coupling through G Proteins (1990) (5)
[Development of an in vitro cardiomyocytes cell model for embryotoxicological and pharmacological studies] (1992) (5)
Enhanced hippocampal type II theta activity AND altered theta architecture in mice lacking the Cav3.2 T-type voltage-gated calcium channel (2021) (5)
Co-transplantation of Mesenchymal Stromal Cells and Induced Pluripotent Stem Cell-Derived Cardiomyocytes Improves Cardiac Function After Myocardial Damage (2022) (5)
Zn2+-induced changes in Cav2.3 channel function: An electrophysiological and modeling study (2020) (5)
Different Responses to Drug Safety Screening Targets between Human Neonatal and Infantile Heart Tissue and Cardiac Bodies Derived from Human-Induced Pluripotent Stem Cells (2019) (5)
Protein phosphorylation maintains the normal function of cloned human Cav2.3 channels (2018) (5)
Derivation of es Cells From Early Stage Preimplantation Embryos and Characterisation of their Cardiac Differentiation Potential in Mice (2012) (5)
R-Type Voltage-Gated Ca²⁺ Channels in Cardiac and Neuronal Rhythmogenesis. (2015) (5)
Modulation of L-type calcium current by intracellular magnesium in differentiating cardiomyocytes derived from induced pluripotent stem cells. (2014) (5)
Properties of Ba2+ currents arising from human alpha1E and alpha1Ebeta3 constructs expressed in HEK293 cells: physiology, pharmacology, and comparison to native T-type Ba2+ currents. (1998) (5)
Gender specific click and tone burst evoked ABR datasets from mice lacking the Cav3.2 T-type voltage-gated calcium channel (2019) (5)
Generation of Cardiomyocytes in Pipe-Based Microbioreactor Under Segmented Flow (2016) (5)
Stem cells in natural product and medicinal plant drug discovery-An overview of new screening approaches. (2020) (5)
Sunday, 26 August 2012 (2012) (5)
Unconjugated bilirubin modulates neuronal signaling only in wild‐type mice, but not after ablation of the R‐type/Cav2.3 voltage‐gated calcium channel (2018) (5)
Impurity of Stem Cell Graft by Murine Embryonic Fibroblasts – Implications for Cell-Based Therapy of the Central Nervous System (2014) (5)
Gelatine Microspheres Support Direct Intramyocardial Delivery of Induced Pluripotent Stem Cell-Derived Cardiomyocytes (2015) (4)
The influence of melatonin on the heart rhythm - An in vitro simulation with murine embryonic stem cell derived cardiomyocytes. (2021) (4)
Salicylic diamines selectively eliminate residual undifferentiated cells from pluripotent stem cell-derived cardiomyocyte preparations (2021) (4)
Persistence of intramyocardially transplanted murine induced pluripotent stem cell-derived cardiomyocytes from different developmental stages (2021) (4)
Generation of a double-fluorescent double-selectable Cre/loxP indicator vector for monitoring of intracellular recombination events (2008) (4)
Ketamine Increases Proliferation of Human iPSC-Derived Neuronal Progenitor Cells via Insulin-Like Growth Factor 2 and Independent of the NMDA Receptor (2019) (4)
Poster session 2 (2004) (4)
Caldesmon ablation in mice causes umbilical herniation and alters contractility of fetal urinary bladder smooth muscle (2021) (4)
Long Term Perinatal Deltamethrin Exposure Alters Electrophysiological Properties of Embryonic Ventricular Cardiomyocyte (2019) (4)
Epac-mediated relaxation in murine basilar arteries depends on membrane permeability of cyclic nucleotide analogues and endothelial aging. (2020) (4)
Non-Mendelian inheritance during inbreeding of Cav3.2 and Cav2.3 deficient mice (2020) (4)
Data Acquisition and Analysis In Brainstem Evoked Response Audiometry In Mice. (2019) (4)
ATP-dependent potassium channels in the cardiac cell. (1987) (4)
NCX current in the murine embryonic heart: development-dependent regulation by Na+. (2007) (4)
Radiation Response of Murine Embryonic Stem Cells (2020) (4)
[Microcinematographic studies on neurodifferentiation and neurotoxicity in vitro using mouse embryonic stem cells] (1998) (4)
Analyzing murine electrocardiogram with PhysioToolkit. (2010) (4)
Impact of Poly(dimethylsiloxane) Surface Modification with Conventional and Amino Acid-Conjugated Self-Assembled Monolayers on the Differentiation of Induced Pluripotent Stem Cells into Cardiomyocytes. (2021) (3)
Modeling Genetic Cardiac Channelopathies Using Induced Pluripotent Stem Cells - Status quo from an Electrophysiological Perspective. (2021) (3)
Murine Short Axis Ventricular Heart Slices for Electrophysiological Studies. (2017) (3)
Calcium currents of neuroblastoma × glioma hybrid cells after cultivation with dibutyryl cyclic AMP and nickel (1990) (3)
Heat shock proteins and ion channels. Functional interactions and therapeutic consequences. (2010) (3)
Implication of therapeutic cloning for organ transplantation. (2004) (3)
Retinal Vessel Responses to Flicker Stimulation Are Impaired in Cav2.3-Deficient Mice—An in-vivo Evaluation Using Retinal Vessel Analysis (RVA) (2021) (3)
Hormonal modulations of calcium channel activity. (1993) (3)
Thymosin β4 impeded murine stem cell proliferation with an intact cardiovascular differentiation (2016) (3)
Dynamic Support Culture of Murine Skeletal Muscle-Derived Stem Cells Improves Their Cardiogenic Potential In Vitro (2015) (3)
Stem cell engineering : principles and applications (2011) (3)
Interaction of recombinant and native Cav2.3 E-/R-type voltage-gated Ca2+ channels with the molecular chaperone Hsp70 (2011) (3)
Pacsin 2 is required for the maintenance of a normal cardiac function in the developing mouse heart (2017) (3)
Monday, 27 August 2012 (2012) (3)
Engineering of cardiac microtissues by microfluidic cell encapsulation in thermoshrinking non-crosslinked PNIPAAm gels (2022) (3)
[Establishment of an in vitro model system for the differentiation of synaptically coupled neurons from mouse embryonic stem cells] (1995) (3)
Non-invasive Assessment of Neurovascular Coupling After Aneurysmal Subarachnoid Hemorrhage: A Prospective Observational Trial Using Retinal Vessel Analysis (2021) (3)
Functional implications of Cav2.3 R‐type voltage‐gated calcium channels in the murine auditory system – novel vistas from brainstem‐evoked response audiometry (2020) (3)
Cellular response on Auger- and Beta-emitting nuclides: Human embryonic stem cells (hESC) vs. keratinocytes (2012) (3)
QuinoMit Q10-Fluid attenuates hydrogen peroxide-induced irregular beating in mouse pluripotent stem cell-derived cardiomyocytes. (2021) (3)
Corrigendum: Gene profiling of embryonic skeletal muscle lacking type I ryanodine receptor Ca2+ release channel (2016) (3)
Microgravity-induced stress mechanisms in human stem cell-derived cardiomyocytes (2022) (3)
In Vitro Methods for Cardiotoxicity Testing (2014) (3)
Stem cells and differentiation – a synoptic review of patents granted since 2009 (2015) (3)
Chromosome tracking in fused cells by single nucleotide polymorphisms. (2015) (2)
Transcription Factors, Growth Factors, and Signal Cascades Capable of Priming Cardiogenesis (2004) (2)
Tumor‐induced angiogenesis studied in confrontation cultures of multicellular tumor spheroids and embryoid bodies grown from pluripotent embryonic stem cells (2001) (2)
Functional Toxicology and Pharmacology Test of Cell Induced Mechanical Tensile Stress in 2D and 3D Tissue Cultures (2018) (2)
Protein Interaction Partners of Cav2.3 R-Type Voltage-Gated Calcium Channels (2013) (2)
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach (2012) (2)
Intracerebroventricular administration of histidine reduces kainic acid-induced convulsive seizures in mice (2019) (2)
Label-Free Impedance Measurements for Profiling Drug-Induced Cardiotoxicity (2015) (2)
Enhanced hippocampal type II theta activity AND altered theta architecture in mice lacking the Cav3.2 T-type voltage-gated calcium channel (2021) (2)
Transient membrane hyperpolarizations due to spontaneous fluctuations of the cytosolic Ca2+ in osteoblast-like cells (2004) (2)
Imaging Herpes Simplex Virus Type 1 Amplicon Vector–Mediated Gene Expression in Human Glioma Spheroids (2011) (2)
The Potential Application of Biomaterials in Cardiac Stem Cell Therapy. (2016) (2)
NCX Current in the Murine Embryonic Heart (2007) (2)
ATROPINE-SENSITIVE HIPPOCAMPAL THETA OSCILLATIONS ARE MEDIATED BY Cav 2 . 3 R-TYPE Ca 2 (2)
High-efficient serum-free differentiation of endothelial cells from human iPS cells (2022) (2)
Mechano-Pharmacological Testing of L-Type Ca2+ Channel Modulators via Human Vascular Celldrum Model. (2020) (2)
Alternative Embryonic Stem Cell Sources (2009) (2)
“Watching the Detectives” report of the general assembly of the EU project DETECTIVE Brussels, 24–25 November 2015 (2016) (2)
Injection of isolated subunits of cAMP-dependent protein kinase II into single adult cardiac myocytes modulates the slow Ca++ inward current (1982) (2)
Human Pluripotent Stem Cell Applications in Drug Discovery and Toxicology – An overview (2014) (2)
Stem cells-derived natural killer cells for cancer immunotherapy: current protocols, feasibility, and benefits of ex vivo generated natural killer cells in treatment of advanced solid tumors (2021) (2)
[From basic research to the clinic. Obstacles and options for stem cell therapies]. (2008) (2)
Cation channels in oocytes and early states of development: a novel type of nonselective cation channel activated by adrenaline in a clonal mesoderm-like cell line (MES-1). (1993) (2)
Gender specific click and tone burst evoked ABR datasets from mice lacking the Cav2.3 R-type voltage-gated calcium channel (2018) (2)
Derivation of induced pluripotent stem (iPS) cells from a patient with an arrhythmogenic right ventricular cardiomyopathy (ARVC). (2010) (2)
Conrad et al. reply (2010) (2)
Pressure-controlled Intermittent Coronary Sinus Occlusion (PICSO) study on mechanical control of cardiac tissue morphogenesis (2012) (2)
A Method for the Real‐Time Observation of Endodermal Cell Behavior on Micropatterned Surfaces (2009) (2)
A New Model to Perform Electrophysiological Studies in the Early Embryonic Mouse Heart (2013) (2)
STAT3 Phosphorylation Mediating DMSO's Function on Fetal Cardiomyocyte Proliferation with Developmental Changes. (2019) (2)
[Human calcium channelopathies. Voltage-gated Ca(2+) channels in etiology, pathogenesis, and pharmacotherapy of neurologic disorders]. (2008) (2)
Gi 2 and protein kinase C are required for thyrotropin-releasing hormone-induced stimulation of voltage-dependent Ca 2 + channels in rat pituitary GH 3 cells ( cytoplasmic caldum / G proteins / pertusss toxin / sal sduction / anense oligonucleotides ) (2005) (2)
Stem cells for regenerative medicine and anti-aging. (2019) (1)
Assessment of the In Vitro Cytotoxicity Effects of the Leaf Methanol Extract of Crinum zeylanicum on Mouse Induced Pluripotent Stem Cells and Their Cardiomyocytes Derivatives (2021) (1)
Experimentally Induced Convulsive Seizures Are Modulated in Part by Zinc Ions through the Pharmacoresistant Cav2.3 Calcium Channel. (2020) (1)
Evaluation of chemotherapy with nanosomal paclitaxel and gene therapy expressing apoptosis-inducing proteins in the management of spontaneous canine mammary neoplasm. (2019) (1)
Development of the Cardiovascular System in Embryoid Bodies Derived from Embryonic Stem Cells (2004) (1)
Stem Cell Engineering (2011) (1)
The funGenES consortium (2006) (1)
Generation of transgene-free induced pluripotent stem cells from cardiac fibroblasts of goat embryos. (2020) (1)
Murine embryonic stem cell differentiation into cardiomyocytes requires L-type Ca2+ channel activity. (2007) (1)
Acquisition of chromosome 1q duplication in parental and genome‐edited human‐induced pluripotent stem cell‐derived neural stem cells results in their higher proliferation rate in vitro and in vivo (2020) (1)
Spontaneous long-term and urethane induced hippocampal EEG power, activity and temperature data from mice lacking the Cav3.2 voltage-gated Ca2+ channel (2021) (1)
Effects of spermine NONOate and ATP on the thermal stability of hemoglobin (2012) (1)
Global transcriptomic analysis of murine embryonic stem cell-derived cardiomyocytes. (2007) (1)
Altered Functional Expression of β-Adrenergic Receptors in Rhesus Monkey Embryonic Stem Cell-Derived Cardiomyocytes. (2017) (1)
[Chronic intermittent hypoxia decreases acute hypoxic inhibition of voltage-gated potassium channel in rat pulmonary arterial smooth muscle cells]. (2004) (1)
Ionic Currents in Carotid Body Type I Cells and the Effects of Hypoxia and NaCN (1990) (1)
Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells (2018) (1)
Involvement of Pertussis Toxin-Sensitive G-Proteins in the Modulation of Voltage-Dependent Ca2+ Channels by Extracellular Signals (1989) (1)
[Bidirectional hormonal modulation of voltage dependent ca2+ channels]. (1989) (1)
Human-Induced Pluripotent Stem Cells, Embryonic Stem Cells, and Their Cardiomyocyte Derivatives: An Overview (2013) (1)
Regulation of the Ca-Channel by Phosphorylation-Dephosphorylation (1987) (1)
Co-transplanted non-cardiomyocytes enhance early persistence of induced pluripotent stem cell derived cardiomyocytes after intramyocardial injection but they also proliferate in loco over time (2013) (1)
Introduction of the Biokinemetric Triangle - a New Surrogate Parameter for Analysis of Spinal Range of Motion (2018) (1)
Long-term persistence, functional integration and electrophysiological properties of transplanted cardiomyocytes derived from induced pluripotent stem cells (2013) (1)
Embryonic Stem Cell Derived Cardiogenesis and Myogenesis (1994) (1)
Approaches to Studying the Interaction between G-Proteins and Voltage- Dependent Ca2+ Channels (1993) (1)
NO Underlies the Muscarinic Receptor-Mediated Inhibition of If in Early Embryonic Heart Cells (2007) (1)
Inflammatory Pre-conditioning of Adipose Derived Stem Cells (ADSCs) with Cerebrospinal Fluid (CSF) from Traumatic Brain Injury Patients Alters the Immunomodulatory Potential of ADSC Secretomes. (2021) (1)
Ablation of the CaV2.3 containing E-type voltage-gated calcium channel results in cardiac arrhythmia and altered autonomic control within the murine cardiovascular system (2005) (1)
The influence of light on the beat rate variability of murine embryonic stem cell derived cardiomyocytes. (2021) (1)
A Cre-based double fluorescence indicator system for monitoring cell fusion events and selection of fused cells. (2010) (1)
Multiple nickel‐sensitive targets elicit cardiac arrhythmia in isolated mouse hearts after pituitary adenylate cyclase‐activating polypeptide‐mediated chronotropy (2017) (1)
Regulation and function of ATP-dependent K+ channels (1989) (1)
Disturbances of Transretinal Signaling After Ablation of Ca(V)2.3 / R-Type Calcium Channels (2018) (1)
Senescent murine femoral arteries undergo vascular remodelling associated with accelerated stress‐induced contractility and reactivity to nitric oxide (2021) (1)
Different signal molecules involved in the muscarinic modulation of pacemaker current I(f) on the heart of mouse embryo in different developmental stages. (2005) (1)
Sunday, 18 July 2010 (2010) (0)
Inhibition of hypoxia-induced apoptosis in induced pluripotent stem cell derived cardiomyocytes (2013) (0)
The FunGenES consortium: functional genomics in engineered embryonic stem cells. (2006) (0)
Live-Cell Imaging of the Contractile Velocity and Transient Intracellular Ca2+ Fluctuations in Human Stem Cell-Derived Cardiomyocytes (2022) (0)
mRNA translational specialization by RBPMS presets the competence for cardiac commitment in hESCs (2023) (0)
C ardiac speciﬁc differentiation of mouse embryonic stem cells (2003) (0)
Correction: Nemade, H.; et al. Cyclooxygenases Inhibitors Efficiently Induce Cardiomyogenesis in Human Pluripotent Stem Cells. Cells 2020, 9, 554 (2020) (0)
P1 The Cav2.3 E/R-Type Ca2+ channel is a modulator of rodent sleep architecture (2011) (0)
Cardiovascular genomics (2006) (0)
Culture of Embryoid Bodies (2005) (0)
[Decrease of extracellular pH modulates the whole cell voltage-gated potassium currents in rat pulmonary artery smooth muscle cells]. (2007) (0)
Development of Pacemaker Activity in Embryonic and Embryonic Stem Cell-Derived Cardiomyocytes (2011) (0)
Catechins with a galloyl group in the 3-position inhibit the PDGF-BB-induced intracellular signal transduction pathway and proliferation of vascular smooth muscle cells (2002) (0)
Effect of Ethanolic Extract of Vernonia amygdalina on the Proliferation, Viability and Function of Mouse Induced Pluripotent Stem Cells and Cardiomyocytes (2023) (0)
Inversion of Ca2+ current modulation during recovery of neuroblastoma cells from pertussis toxin pretreatment (2001) (0)
Endogenous vasodilators reduce arterial tone by activation of K+ channels (1990) (0)
Aspects of Embryonic Stem Cell Derived Somatic Cell Therapy of Degenerative Diseases (2008) (0)
Calcium Signaling Properties of Control and CPVT-Expressing Human ipscs-Derived Cardiomyocytes (2013) (0)
Selected aspects of retinal signaling and energy metabolism and its perspective as a cerebral surrogate model (2018) (0)
Establishment of (cid:98) -Adrenergic Modulation of L-Type Ca 2 (cid:49) Current in the Early Stages of Cardiomyocyte Development (1999) (0)
In Reply to "Corpus Callosotomy for Drug-Resistant Schizophrenia; Novel Treatment Based on Pathophysiology". (2018) (0)
Cardiomyocyte derived from induced pluripotent stem cells are more sensitive to ischemia then naïve cardiomyocytes (2014) (0)
Recent Topics in Gravitational Biology Research at the DLR Institute of Aerospace Medicine (2016) (0)
Generation and selection of hepatocyte-like cells from transgenic murine embryonic stem cells at different differentiation stages. (2010) (0)
Retraction Statement. Paper by Zhao Y, Li X, Sun X, Zhang Y, Ren H: Cell Physiol Biochem 2012;29:341-352 (DOI: 10.1159/000338489) (2016) (0)
Extracellular Ca2+ sensing in C-cells and parathyroid cells. (1992) (0)
Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Toxukn and STOP-Toxukk tests (2016) (0)
Scalable Generation of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. (2021) (0)
Implications of chemopreventive agents in differentiation of mouse embryonic stem cell derived embryoid bodies. (2010) (0)
Tissue engineering with embryonic stem cells (2005) (0)
Evaluation of Mesenchymal Stem Cells with Conditioned Media and m-EGF for Regeneration of Liver Tissue After Partial Hepatectomy in Wistar Rats. (2021) (0)
WITHDRAWN: Capsaicin inhibits beta-adrenergically-activated Na(+) current through endogenous calcineurin in cardiac myocytes. (2010) (0)
[The simultaneous isolation of outer hair cells and Deiters' cells from the cochlea of the guinea pig]. (2003) (0)
[Extracellular calcium modulates the whole cell potassium currents in Deiters cells isolated from guinea pig cochlea]. (2005) (0)
Response (2008) (0)
Cav3 T-Type Voltage-Gated Ca2+ Channels and the Amyloidogenic Environment: Pathophysiology and Implications on Pharmacotherapy and Pharmacovigilance (2022) (0)
Electrophysiological Properties of Tetraploid Cardiomyocytes Derived from Murine Pluripotent Stem Cells Generated by Fusion of Adult Somatic Cells with Embryonic Stem Cells (2023) (0)
CTL Stem Cells from Lysis by Antigen-Specific Serpin-6 Expression Protects Embryonic (2007) (0)
[Effect of linopirdine on potassium currents in isolated outer hair cells and Deiters' cells of the cochlea from guinea pig]. (2003) (0)
System for cell- and development-specific selection of differentiating embryonic stem cells, adult stem cells and embryonic germ cells (2001) (0)
Skeletal Myoblast Tissue Engineering for Myocardial Regeneration (2009) (0)
Embryonic Stem Cells and Their Therapeutic Potential (2008) (0)
Functional cardiotoxicity assessment of cosmetic compounds using human-induced pluripotent stem cell-derived cardiomyocytes (2017) (0)
Does an Inward-Rectifying K Channel Regulate Type-I Cell Response to Hypoxia? (1990) (0)
Pharmacological properties of receptor for ATP involved in activation of Ca2+ influx in RBL-2H3 cells (1994) (0)
ROK and RSK2-kinase pathways differ between senescent human renal and mesenteric arteries. (2023) (0)
Extracellular Signal-Regulated Kinase 1 / 2 Pathway Gangliosides GM 1 and GM 2 Induce Vascular Smooth Muscle Cell Proliferation via (2001) (0)
High-efficient serum-free differentiation of endothelial cells from human iPS cells (2022) (0)
Spontaneous Ca2+ Oscillations in Beating Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes (HIPSC-CM) and Rat Neonatal Cardiomyocytes (RN-CM) (2012) (0)
Submicromolar copper (II) ions stimulate transretinal signaling in the isolated retina from wild type but not from Cav2.3-deficient mice (2019) (0)
Embryo toxicity of all-trans-retinoic acid in human embryonic stem cells (2012) (0)
Transcription factors, growth factors and signal cascades capable of priming morphogenesis of heart (2004) (0)
Erratum (Retracted article): (November 18, 2002) 196, 10, (1291-1305) (2006) (0)
Dual thick and thin filament linked regulation of stretch- and L-NAME-induced tone in young and senescent murine basilar artery (2023) (0)
Development of pacemaker activity in cardiac myocytes derived from embryonic stem cells (2001) (0)
Correction to: Toxicogenomics directory of chemically exposed human hepatocytes (2022) (0)
In memoriam Prof. Dr. Wolfgang Trautwein (2011) (0)
Adult and Embryonic Stem Cell Therapy (2008) (0)
Pipette-based Method to Study Embryoid Body Formation Derived from Mouse and Human Pluripotent Stem Cells Partially Recapitulating Early Embryonic Development Under Simulated Microgravity Conditions (2015) (0)
Test systems of developmental toxicity: state-of-the art and future perspectives (2013) (0)
Comparison of a teratogenic transcriptome-based predictive test based on human embryonic versus inducible pluripotent stem cells (2016) (0)
The pluripotency involved factors, Lin28 and Notch1 are targets of neuronal miRNAs in hepatic stellate cells (2015) (0)
Stem cells for the treatment of stroke: malignant transformation of homologous transplants (2002) (0)
Combining Hypoxia and Bioreactor Hydrodynamics Boosts Induced Pluripotent Stem Cell Differentiation Towards Cardiomyocytes (2014) (0)
Depletion of Mageb16 induces differentiation of pluripotent stem cells predominantly into mesodermal derivatives (2017) (0)
PLURIPOTENT STEM CELLS FROM BASIC RESEARCH TO POSSIBLE CLINICAL APPLICATION; INVITED SPEAKERS (2012) (0)
Session V5 : Developments in stem cell research as the basis for sustainable availability of differentiated human cells and tissues (2011) (0)
Cardiac Cell Replacement Therapy With Pluripotent Stem Cell Derived Cardiomyocytes (2014) (0)
“Watching the Detectives” report of the general assembly of the EU project DETECTIVE Brussels, 24–25 November 2015 (2016) (0)
Specific Gene Signatures and Pathways in Mesodermal Cells and Their Derivatives Derived from Embryonic Stem Cells (2011) (0)
Contents Vol. 29, 2012 (2012) (0)
Adult and Pluripotent Stem Cells (2014) (0)
Cross-Cluster Cooperation (2013) (0)
Effect of different serums on culture and growth pattern on equine adipose derived mesenchymal stem cells (hrs-AT MSC) (2021) (0)
Functional Characterization and Gene Expression Profiling of α-Smooth Muscle Actin Expressing Cardiomyocytes Derived from Murine Induced Pluripotent Stem Cells (2011) (0)
Role of LIF/STAT3 signaling in the regulation of major histocompatibility complex class I molecules in murine embryonic stem cells. (2010) (0)
Persistence of intramyocardially transplanted murine induced pluripotent stem cell-derived cardiomyocytes from different developmental stages (2021) (0)
Microgravity-Induced Senescence Mechanisms in Human Stem Cell-Derived Cardiomyocytes (2021) (0)
Poly(acrylamide) Spheroids with Tunable Elasticity for Scalable Cell Culture Applications (2022) (0)
Evidence for self-maintaining pluripotent murine stem cells in embryoid bodies (2013) (0)
Contents Vol. 26, 2010 (2011) (0)
From Dolly to hiPS: New insights into reprogramming (2010) (0)
Reconsidering pluripotency tests: Do we still need teratomas? (2011) (0)
In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities (2016) (0)
Complex Clearance Mechanisms After Intraventricular Hemorrhage and rt-PA Treatment—a Review on Clinical Trials (2019) (0)
Effect of Different Oxygen Tension on Culture and Growth Pattern of Horse Adipose Tissue and Umbilical Cord Blood Derived Mesenchymal Stem Cells (hrs-AT-MSC and hrs-UCB-MSC) (2022) (0)
Reproducible and complete early separation of stem and feeder cells does not attenuate the differentiation potential of feeder-freed stem cells. (2007) (0)
READERS' COMMENTS Are Improvements in Cardiac Function Due to Stem Cell Uptake and Engraftment? (2005) (0)
Lineage of conversion of skeletal muscle derived precursor cells into cardiomyocytes - a promising autologous cell source for cardiac cell therapy. (2010) (0)
Pluripotent stem cells for research and clinical application (2017) (0)
Metabolite signatures of doxorubicin induced toxicity in human induced pluripotent stem cell-derived cardiomyocytes (2017) (0)
Susceptibility of murine induced pluripotent stem cell-derived cardiomyocytes to hypoxia and nutrient deprivation (2015) (0)
Modeling a system tissues embryonic stem (ES) (2004) (0)
Insufficient electrical integration and maturation of transplanted neonatal ventricle patches (2012) (0)
Embryonic Stem Cells, Cardiomyoplasty, and the Risk of Teratoma Formation (2009) (0)
Differentiation of Murine Pluripotent Stem Cells in Cardiomyocytes (2014) (0)
Wednesday, 29 August 2012 (2012) (0)
Expression of SSEA-1 in different clones of reprogrammed murine embryonic fi brodlasts (2011) (0)
Abstract 14493: Long-Term Survival Enables a High Quality of Electrical Integration of Transplanted Induced Pluripotent Stem Cell Derived Cardiomyocytes (2013) (0)
P2543Electrical integration and persistence of transplanted induced pluripotent stem cell-derived cardiomyocytes from different developmental stages (2017) (0)
[Isolation of partial outer supporting cells from guinea pig cochlea]. (2004) (0)
P1454 | BENCH Electrical integration, maturation and persistence of transplanted fetal cardiomyocytes from different developmental stages (0)
Abstract 9917: Electrical Coupling and Action Potential Properties of Transplanted Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Comparison with Fetal Cardiomyocytes (2012) (0)
Subject Index Vol. 165, 1999 (1999) (0)
PDGF-BB induces selective differentiation of mouse embryonic stem cells to cardiac cells (2002) (0)
Influence of cocultivation with vital and ischemic ventricular tissue on electrophysiological properties of embryonic stem cell–derived cardiomyocytes (2010) (0)
Transplantation of embryonic stem cell-derived cardiomyocytes (2004) (0)
Abstract of the 68th Meeting (Spring Meeting) 6–9 March 1990, Heidelberg (1990) (0)
Abstract 1089: Functional Expression and Regulation of the Embryonic Na+/Ca2+ Exchanger (2006) (0)
Live Monitoring of the Endodermlike Cell Differentiation in the Murine Embryonic Stem Cell System (2004) (0)
Supplementary Material for: Embryonic Stem Cells Facilitate the Isolation of Persistent Clonal Cardiovascular Progenitor Cell Lines and Leukemia Inhibitor Factor Maintains Their Self-Renewal and Myocardial Differentiation Potential in vitro (2017) (0)
Endothelial Progenitor Cells Are Capable of Vascular Tube-Like Structure Formation Upon Direct Contact with Living but not Ischemic Cardiac Tissue: 2412 (2012) (0)
Low concentrations of ethanol but not of dimethyl sulfoxide (DMSO) impair reciprocal retinal signal transduction (2015) (0)
Functional expression and regulation of If during cardio-myogenesis (1999) (0)
Ca2+ Signaling in Cardiomyocytes Derived from Human Induced Pluripotent Stem Cells (hIPSC) (2012) (0)
Pluripotent stem cells – from physiology to cell therapy, disease models and test systems (2014) (0)
Comparison of Methods for Cardiomyocyte Differetiation of Murine Embryonic Stem and Induced Pluripotent Cells (2011) (0)
Ground-Based Facilities at the DLR Institute of Aerospace Medicine for Studies in Gravitational Biology (2015) (0)
Electrical integration, maturation and persistence of transplanted fetal cardiomyocytes from different developmental stages (2013) (0)
Construction of Reporter Plasmid With the Acta 2 Promoter and EGFP and Generation of the Acta 2 ESC Line (2008) (0)
Towards a Medically Approved Technology for Large-Scale Stem Cell Banks: Tools and Methods (2008) (0)
Toxicogenomics directory of chemically exposed human hepatocytes (2014) (0)
Studies on the Mechanism of Action of D 600 on Isolated Myocytes (1984) (0)
MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes (2016) (0)
Roles of the Kv1.2, Kv1.5, Kv2.1 potassium channels in hypoxia pulmonary vasoconstriction (2004) (0)
BLTK 1 murine Leydig tumor cells : a novel model for evaluating the steroidogenic effects of reproductive and developmental toxicants (2011) (0)
Characterization of microelectrode array field potentials (2006) (0)
Implication of therapeutic cloning for organ transplantation. Discussion (2004) (0)
[Investigation on spontaneous electrical activity of murine embryonic heart using microelectrode arrays]. (2006) (0)
Abstract 12899: A Novel Model to Perform Electrophysiological Studies in the Embryonic Mouse Heart (2010) (0)
PLURIPOTENT STEM CELLS FOR TOXICOLOGICAL SCREENING AND DISEASE MODELS; INVITED SPEAKERS (2012) (0)
Saturday, 17 July 2010 (2010) (0)
ArticleRadiation Response of Murine Embryonic Stem CellsChristine E. Hellweg 1** (2020) (0)
Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex (2018) (0)
Embryonic stem cells differentiation substantiates thalidomide teratogenicity (2012) (0)
Embryonic Stem‐cell‐derived Cardiomyocytes as a Model For Arrhythmia (2007) (0)
CTLCells from Lysis by Antigen-Specific Serpin-6 Expression Protects Embryonic (2013) (0)
Abstract 16620: Electrical Integration of Transplanted Cardiomyocytes Derived from Induced Pluripotent Stem Cells (2010) (0)
Identification of G-Proteins Involved in the Inhibition of Ca2+ Currents in Neuronal and Endocrine Cells (1992) (0)
Isolation and Functional Characterization of D DD D -Smooth Muscle Actin Expressing Cardiomyo- cytes from Embryonic Stem Cells (2016) (0)
Effects of (‐)bicuculline and gamma‐aminobutyric acid on the NiCl2 mediated stimulation of the ERG b‐wave amplitude from the isolated superfused vertebrate retina (2007) (0)

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