Jukka A. Takala
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Philosophy
Jukka A. Takala's Degrees
- PhD Medical Sciences University of Helsinki
- Doctorate Medicine University of Helsinki
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(Suggest an Edit or Addition)Jukka A. Takala's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Dexmedetomidine vs midazolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. (2012) (744)
- Increased mortality associated with growth hormone treatment in critically ill adults. (1999) (669)
- A Prospective, Randomized Study of Goal-Oriented Hemodynamic Therapy in Cardiac Surgical Patients (2000) (525)
- Measurement of gas exchange in intensive care: laboratory and clinical validation of a new device. (1989) (328)
- Comparison of continuous and intermittent renal replacement therapy for acute renal failure. (2005) (318)
- Costs of care, long-term prognosis and quality of life in patients requiring renal replacement therapy during intensive care (2000) (234)
- Determinants of splanchnic blood flow. (1996) (230)
- Dexmedetomidine versus propofol/midazolam for long-term sedation during mechanical ventilation (2009) (220)
- Siglec-9 transduces apoptotic and nonapoptotic death signals into neutrophils depending on the proinflammatory cytokine environment. (2005) (216)
- Causes of death and determinants of outcome in critically ill patients (2006) (206)
- Association of arterial blood pressure and vasopressor load with septic shock mortality: a post hoc analysis of a multicenter trial (2009) (205)
- Pantoprazole in Patients at Risk for Gastrointestinal Bleeding in the ICU (2018) (190)
- Gastric mucosal pH does not reflect changes in splanchnic blood flow after cardiac surgery. (1995) (152)
- Acute respiratory distress syndrome: frequency, clinical course, and costs of care. (1999) (145)
- The effect of carbon dioxide, respiratory rate and tidal volume on human heart rate variability (2004) (145)
- Quality of life after prolonged intensive care. (1999) (138)
- Effects of cerebral perfusion pressure and increased fraction of inspired oxygen on brain tissue oxygen, lactate and glucose in patients with severe head injury (2003) (137)
- Saline Pco2 is an important source of error in the assessment of gastric intramucosal pH (1994) (136)
- Estimation of splanchnic blood flow by the Fick principle in man and problems in the use of indocyanine green. (1995) (131)
- Dysphagia in Mechanically Ventilated ICU Patients (DYnAMICS): A Prospective Observational Trial (2017) (129)
- Re-thinking resuscitation: leaving blood pressure cosmetics behind and moving forward to permissive hypotension and a tissue perfusion-based approach (2013) (128)
- Mitochondrial function in sepsis (2013) (124)
- Thromboelastometry for the assessment of coagulation abnormalities in early and established adult sepsis: a prospective cohort study (2009) (113)
- Effect of dopexamine on outcome after major abdominal surgery: A prospective, randomized, controlled multicenter study (2000) (108)
- Dobutamine-induced dissociation between changes in splanchnic blood flow and gastric intramucosal pH after cardiac surgery. (1995) (104)
- Pulse-pressure variation and hemodynamic response in patients with elevated pulmonary artery pressure: a clinical study (2010) (103)
- 36th International Symposium on Intensive Care and Emergency Medicine (2016) (103)
- Gut permeability in patients with acute pancreatitis. (2000) (101)
- Time-pattern of lactate and lactate to pyruvate ratio in the first 24 hours of intensive care emergency admissions. (2000) (100)
- Effect of sedation level on the prevalence of delirium when assessed with CAM-ICU and ICDSC (2013) (99)
- Resource use in the ICU: short‐ vs. long‐term patients * (2003) (96)
- Effect of fluid resuscitation on mortality and organ function in experimental sepsis models (2009) (95)
- Multicentre study on peri- and postoperative central venous oxygen saturation in high-risk surgical patients (2006) (92)
- Procalcitonin Concentrations in Patients with Neutropenic Fever (1999) (92)
- Safe long-distance interhospital ground transfer of critically ill patients with acute severe unstable respiratory and circulatory failure (2002) (92)
- Regional blood flow and oxygen transport in patients with the low cardiac output syndrome after cardiac surgery (1993) (91)
- Effects of prolonged endotoxemia on liver, skeletal muscle and kidney mitochondrial function (2006) (91)
- Effects of TLR Agonists on the Hypoxia-Regulated Transcription Factor HIF-1α and Dendritic Cell Maturation under Normoxic Conditions (2010) (87)
- Angiotensin II in septic shock (2015) (83)
- Intestinal luminal microdialysis: a new approach to assess gut mucosal ischemia. (1999) (82)
- Outcome and resource utilization in gastroenterological surgery (2001) (81)
- Effect of tidal volume on gas exchange and oxygen transport in the adult respiratory distress syndrome. (1992) (78)
- Dysfunction of respiratory muscles in critically ill patients on the intensive care unit (2016) (76)
- Effect of vasoactive treatment on the relationship between mixed venous and regional oxygen saturation (1991) (75)
- Effects of Dopamine on Systemic and Regional Blood Flow and Metabolism in Septic and Cardiac Surgery Patients (2002) (75)
- Splanchnic perfusion during hemodialysis: Evidence for marginal tissue perfusion (2001) (68)
- Outcome after acute traumatic subdural and epidural haematoma in Switzerland: a single-centre experience. (2008) (68)
- Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study (2007) (67)
- Estimation of central venous pressure by ultrasound. (2005) (67)
- Dexmedetomidine versus standard care sedation with propofol or midazolam in intensive care: an economic evaluation (2015) (66)
- Diagnosis and management of electrolyte emergencies. (2003) (64)
- Sampling rate causes bias in APACHE II and SAPS II scores (2000) (64)
- Effect of positive end-expiratory pressure on splanchnic perfusion in acute lung injury (2000) (62)
- Prevention of systemic hyperlactatemia during splanchnic ischemia. (2000) (61)
- Muscle membrane dysfunction in critical illness myopathy assessed by velocity recovery cycles (2011) (60)
- Validation of a new respiratory inductive plethysmograph (2001) (60)
- Effects of Vasopressin on Microcirculatory Blood Flow in the Gastrointestinal Tract in Anesthetized Pigs in Septic Shock (2007) (60)
- Physiologic response to changing positive end-expiratory pressure during neurally adjusted ventilatory assist in sedated, critically ill adults. (2010) (60)
- Increasing mean arterial blood pressure in sepsis: effects on fluid balance, vasopressor load and renal function (2013) (59)
- Change in stroke volume in response to fluid challenge: assessment using esophageal Doppler (2003) (59)
- The Haldane effect--an alternative explanation for increasing gastric mucosal PCO2 gradients? (1999) (58)
- Effect of PEEP, blood volume, and inspiratory hold maneuvers on venous return. (2016) (58)
- Angiotensin II in Septic Shock: Effects on Tissue Perfusion, Organ Function, and Mitochondrial Respiration in a Porcine Model of Fecal Peritonitis* (2014) (57)
- Effect of treatment delay on disease severity and need for resuscitation in porcine fecal peritonitis (2012) (57)
- Evaluation of respiratory inductive plethysmography in the measurement of breathing pattern and PEEP-induced changes in lung volume. (1992) (57)
- Pulmonary capillary pressure. A review. (2006) (56)
- Early non-invasive cardiac output monitoring in hemodynamically unstable intensive care patients: A multi-center randomized controlled trial (2011) (56)
- Lactate metabolism and regional lactate exchange after cardiac surgery. (1996) (55)
- Nitrogen sparing effect of structured triglycerides containing both medium-and long-chain fatty acids in critically ill patients; a double blind randomized controlled trial. (2001) (55)
- Customised prediction models based on APACHE II and SAPS II scores in patients with prolonged length of stay in the ICU (2002) (53)
- Pulse pressure variation and volume responsiveness during acutely increased pulmonary artery pressure: an experimental study (2010) (51)
- Splanchnic tissue perfusion in acute experimental pancreatitis. (1999) (51)
- Usefulness of a clinical diagnosis of ICU-acquired paresis to predict outcome in patients with SIRS and acute respiratory failure (2009) (50)
- Effects of systemic arterial hypoperfusion on splanchnic hemodynamics and hepatic arterial buffer response in pigs. (2001) (47)
- Hemodynamic variables and mortality in cardiogenic shock: a retrospective cohort study (2009) (45)
- Hypermetabolism and efficiency of CO2 removal in acute respiratory failure. (1994) (44)
- Haemodynamic variables and functional outcome in hypothermic patients following out-of-hospital cardiac arrest. (2013) (44)
- Should we target blood pressure in sepsis? (2010) (43)
- Metabolic changes after cardiac surgery (2001) (43)
- The effect of dobutamine infusion on splanchnic blood flow and oxygen transport in patients with acute pancreatitis (1997) (43)
- Gut luminal lactate release during gradual intestinal ischemia (2001) (42)
- Hemodynamic assessment of critically ill patients using a miniaturized transesophageal echocardiography probe (2013) (42)
- Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: A randomised controlled trial (2018) (42)
- Does alveolar recruitment occur with positive end-expiratory pressure in adult respiratory distress syndrome patients? (1993) (42)
- The effect of dexmedetomidine on vasopressor requirements in patients with septic shock: a subgroup analysis of the Sedation Practice in Intensive Care Evaluation [SPICE III] Trial (2020) (41)
- Changes in respiratory control induced by amino acid infusions. (1988) (41)
- The effect of dexmedetomidine on vasopressor requirements in patients with septic shock: a subgroup analysis of the Sedation Practice in Intensive Care Evaluation [SPICE III] Trial (2020) (41)
- Randomized, Double-Blind Trial of the Effect of Fluid Composition on Electrolyte, Acid–Base, and Fluid Homeostasis in Patients Early After Subarachnoid Hemorrhage (2013) (41)
- Does ICU length of stay influence quality of life? (2005) (41)
- Hypermetabolism after coronary artery bypass. (1991) (41)
- Relationship between intra‐ and postoperative oxygen transport and prolonged intensive care after cardiac surgery: a prospective study (1997) (41)
- Assessment of the adequacy of systemic and regional perfusion after cardiac surgery. (2000) (40)
- Splanchnic oxygen transport after cardiac surgery: evidence for inadequate tissue perfusion after stabilization of hemodynamics (2005) (40)
- Resource use and outcome in critically ill patients with hematological malignancy: a retrospective cohort study (2008) (39)
- Vasopressin in septic shock: effects on pancreatic, renal, and hepatic blood flow (2007) (38)
- Entropy and bispectral index for assessment of sedation, analgesia and the effects of unpleasant stimuli in critically ill patients: an observational study (2008) (38)
- Oxygen transport and mitochondrial function in porcine septic shock, cardiogenic shock, and hypoxaemia (2012) (38)
- Effects of PEEP on respiratory mechanics after open heart surgery. (1992) (37)
- Severe transfusion-related acute lung injury. (2005) (37)
- Hypoxia inducible factor‐1α induction by tumour necrosis factor‐α, but not by toll‐like receptor agonists, modulates cellular respiration in cultured human hepatocytes (2009) (36)
- A randomized controlled pilot study to evaluate the effect of an enteral formulation designed to improve gastrointestinal tolerance in the critically ill patient—the SPIRIT trial (2017) (35)
- Changes in Splanchnic Circulation During an Alveolar Recruitment Maneuver in Healthy Porcine Lungs (2004) (35)
- Endogenous endotoxemia of intestinal origin during cardiopulmonary bypass — role of type of flow and protective effect of selective digestive decontamination (1997) (35)
- Detection of artifacts in monitored trends in intensive care (2000) (34)
- Auditory Event-Related Potentials, Bispectral Index, and Entropy for the Discrimination of Different Levels of Sedation in Intensive Care Unit Patients (2009) (33)
- Norepinephrine to increase blood pressure in endotoxaemic pigs is associated with improved hepatic mitochondrial respiration (2008) (33)
- Jejunal and gastric mucosal perfusion versus splanchnic blood flow and metabolism: An observational study on postcardiac surgical patients (2000) (32)
- Reconsidering the logic of World Federation of Neurosurgical Societies grading in patients with severe subarachnoid hemorrhage. (2016) (32)
- Right atrial pressure and venous return during cardiopulmonary bypass. (2017) (32)
- Neurally adjusted ventilatory assist in patients with critical illness-associated polyneuromyopathy (2011) (31)
- Intra- and inter-individual variation of BIS-index® and Entropy® during controlled sedation with midazolam/remifentanil and dexmedetomidine/remifentanil in healthy volunteers: an interventional study (2009) (31)
- Evolution of Blood Lactate and 90-Day Mortality in Septic Shock. A Post Hoc Analysis of the FINNAKI Study (2017) (31)
- Dangers of growth hormone therapy in critically ill patients (2000) (31)
- Monitoring the autonomic nervous system in the ICU through cardiovascular variability signals. (1997) (31)
- Bacteriophages Improve Outcome in Experimental Staphylococcus Aureus Ventilator Associated Pneumonia. (2019) (30)
- Metabolic stress modifies the thermogenic effect of dobutamine in man. (1995) (30)
- Splanchnic Vasoregulation During Mesenteric Ischemia and Reperfusion in Pigs (2002) (30)
- Nitrogen and energy balance in septic and injured intensive care patients: response to parenteral nutrition. (1991) (30)
- Increased Hepatosplanchnic Inflammation Precedes the Development of Organ Dysfunction After Elective High-Risk Surgery (2002) (30)
- Toll-like receptor-3-induced mitochondrial dysfunction in cultured human hepatocytes. (2011) (30)
- Cerebral Blood Flow Is Not Altered in Sheep with Pseudomonas aeruginosa Sepsis Treated with Norepinephrine or Nitric Oxide Synthase Inhibition (2003) (30)
- Current approach to the haemodynamic management of septic shock patients in European intensive care units: a cross-sectional, self-reported questionnaire-based survey (2010) (29)
- Risk assessment in the first fifteen minutes: a prospective cohort study of a simple physiological scoring system in the emergency department (2011) (29)
- Measuring Depth of Sedation with Auditory Evoked Potentials During Controlled Infusion of Propofol and Remifentanil in Healthy Volunteers (2004) (29)
- Effects of dobutamine on splanchnic tissue perfusion during partial superior mesenteric artery occlusion (2000) (28)
- The Effects of Dexmedetomidine/Remifentanil and Midazolam/Remifentanil on Auditory-Evoked Potentials and Electroencephalogram at Light-to-Moderate Sedation Levels in Healthy Subjects (2006) (28)
- Mitochondrial function of immune cells in septic shock: A prospective observational cohort study (2017) (27)
- Moderate Carnitine Depletion and Long-Chain Fatty Acid Oxidation, Exercise Capacity, and Nitrogen Balance in the Rat (1994) (27)
- Gastric-arterial PCO2 gradient does not reflect systemic and splanchnic hemodynamics or oxygen transport after cardiac surgery. (2000) (27)
- Epidural analgesia with bupivacaine does not improve splanchnic tissue perfusion after aortic reconstruction surgery. (1998) (27)
- Equilibrating SSC guidelines with individualized care (2021) (26)
- Advances in critical care management of patients undergoing cardiac surgery (2018) (26)
- Effect of dobutamine on splanchnic carbohydrate metabolism and amino acid balance after cardiac surgery. (1999) (26)
- Slow sodium acetate infusion in the correction of metabolic acidosis in premature infants. (1985) (24)
- The pulmonary artery catheter: the tool versus treatments based on the tool (2006) (23)
- Water, Sodium and Acid‐Base Balance in Premature Infants: Therapeutical Aspects (1987) (23)
- A new rabbit model for the study of early brain injury after subarachnoid hemorrhage (2012) (23)
- Systemic and regional effects of experimental gradual splanchnic ischemia. (1997) (23)
- A clinical description of the IMPROVE data library (1997) (23)
- Effect of Dopamine-Induced Changes in Splanchnic Blood Flow on MEGX Production from Lidocaine in Septic and Cardiac Surgery Patients (2002) (22)
- A randomized trial of the effects of the noble gases helium and argon on neuroprotection in a rodent cardiac arrest model (2016) (22)
- Fluid management in patients undergoing cardiac surgery: effects of an acetate- versus lactate-buffered balanced infusion solution on hemodynamic stability (HEMACETAT) (2019) (22)
- Effect of Remifentanil on Mitochondrial Oxygen Consumption of Cultured Human Hepatocytes (2012) (22)
- Decreasing gut wall glucose as an early marker of impaired intestinal perfusion (2006) (22)
- Increasing abdominal pressure with and without PEEP: effects on intra-peritoneal, intra-organ and intra-vascular pressures (2010) (22)
- Gastric mucosal end-tidal PCO2 difference as a continuous indicator of splanchnic perfusion. (2000) (21)
- Dangers of growth hormone therapy in critically ill patients (2002) (21)
- Identification of Adequate Neurally Adjusted Ventilatory Assist (NAVA) During Systematic Increases in the NAVA Level (2011) (21)
- DIFFERENT PATTERNS OF SIGLEC-9-MEDIATED NEUTROPHIL DEATH RESPONSES IN SEPTIC SHOCK (2009) (21)
- Evaluation of a new module in the continuous monitoring of respiratory mechanics (2000) (21)
- Hepatosplanchnic blood flow control and oxygen extraction are modified by the underlying mechanism of impaired perfusion (2005) (20)
- Urinary excretion of polyamines: importance of circadian rhythm, age, sex, menstrual cycle, weight, and creatinine excretion. (1990) (20)
- Measurement of alveolar ventilation and changes in deadspace by indirect calorimetry during mechanical ventilation: A laboratory and clinical validation (1991) (19)
- Sodium nitroprusside after cardiac surgery: systemic and splanchnic blood flow and oxygen transport (1996) (19)
- Changes in regional blood flow and pCO2 gradients during isolated abdominal aortic blood flow reduction (2003) (19)
- Influenza A(H1N1) infection and severe cardiac dysfunction in adults: A case series (2011) (19)
- Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis (2017) (19)
- Changes in respiratory mechanics and gas exchange during the acute respiratory distress syndrome (2006) (19)
- Pressure‐volume relationships in acute lung injury: methodological and clinical implications (2004) (19)
- Single sweep analysis of event related auditory potentials for the monitoring of sedation in cardiac surgery patients (2000) (18)
- Continuous flow left ventricular assist devices: a valid option for heart failure patients. (2012) (18)
- Oxygen extraction in pigs subjected to low‐dose infusion of endotoxin after major abdominal surgery (2005) (18)
- Use of resources and postoperative outcome. (2001) (18)
- Determinants of systemic venous return and the impact of positive pressure ventilation. (2018) (18)
- Extra-intracranial blood shunt mimicking aneurysm rupture: Intracranial-pressure-controlled rabbit subarachnoid hemorrhage model (2010) (18)
- Endogenous endotoxemia of intestinal origin during cardiopulmonary bypass--role of type of flow and protective effect of selective digestive decontamination. (1998) (18)
- Better conduct of clinical trials: The control group in critical care trials (2009) (18)
- Early changes of muscle membrane properties in porcine faecal peritonitis (2014) (17)
- Gastric tonometry in assessing splanchnic tissue perfusion in acute pancreatitis. (2000) (17)
- Reply to "Letter to the editor: Why persist in the fallacy that mean systemic pressure drives venous return?" (2016) (17)
- Gut perfusion in the critically ill (2000) (17)
- Effect of nasogastric suction and ranitidine on the calculated gastric intramucosal pH (1996) (17)
- Effects of Endotoxin and Catecholamines on Hepatic Mitochondrial Respiration (2009) (17)
- Effect of volume status on the estimation of mean systemic filling pressure. (2019) (17)
- Practical sources of error in measuring pulmonary artery occlusion pressure: a study in participants of a special intensivist training program of The Scandinavian Society of Anaesthesiology and Intensive Care Medicine (SSAI) (2006) (16)
- The Effects of Vasoconstriction And Volume Expansion on Veno-Arterial ECMO Flow (2019) (16)
- Volume‐controlled inverse ratio ventilation: effect on dynamic hyperinflation and auto‐PEEP (1993) (16)
- Effects of catecholamines on hepatic and skeletal muscle mitochondrial respiration after prolonged exposure to faecal peritonitis in pigs (2012) (16)
- Delayed heart perforation after blunt trauma. (2002) (16)
- VENOARTERIAL CO2 GRADIENT AFTER CARDIAC SURGERY: RELATION TO SYSTEMIC AND REGIONAL PERFUSION AND OXYGEN TRANSPORT (1997) (16)
- Gender-related differences in aneurysmal subarachnoid hemorrhage: A hospital based study (2017) (15)
- [Acute renal failure in hospitalized patients]. (1995) (15)
- Calculated versus measured oxygen consumption during and after cardiac surgery. Is it possible to estimate lung oxygen consumption? (1997) (15)
- Control groups in recent septic shock trials: a systematic review (2016) (14)
- Lack of effect of ranitidine on gastric luminal pH and mucosal PCO2 during the first day in the ICU (2005) (14)
- Early brain injury linearly correlates with reduction in cerebral perfusion pressure during the hyperacute phase of subarachnoid hemorrhage (2014) (14)
- Heart–lung interactions during neurally adjusted ventilatory assist (2014) (14)
- Orthogonal polarization spectroscopy to detect mesenteric hypoperfusion (2008) (14)
- Hypotension and hypovolemia during hemodialysis: is the usual suspect innocent? (2016) (14)
- Ranitidine or dobutamine alone or combined has no effect on gastric intramucosal-arterial PCO2 difference after cardiac surgery (2000) (14)
- Dose Response of Endotoxin on Hepatocyte and Muscle Mitochondrial Respiration In Vitro (2015) (14)
- Comparison of non-calibrated pulse-contour analysis with continuous thermodilution for cardiac output assessment in patients with induced hypothermia after cardiac arrest. (2011) (14)
- Branched chain amino acid enriched parenteral nutrition in surgical intensive care patients. (1986) (13)
- Angiotensin converting enzyme inhibition has no effect on blood pressure and splanchnic perfusion after cardiac surgery. (1998) (13)
- IBIS Data Library: clinical description of the Finnish database (2000) (13)
- Jejunal luminal microdialysate lactate in cardiac tamponade – effect of low systemic blood flow on gut mucosa (2002) (13)
- Continual hemodynamic monitoring with a single-use transesophageal echocardiography probe in critically ill patients with shock: a randomized controlled clinical trial (2019) (13)
- Assessment of splanchnic blood flow using magnetic resonance imaging (2009) (12)
- Respiratory and sleep patterns during nocturnal infusions of branched chain amino acids (1990) (12)
- No evidence for a local renin-angiotensin system in liver mitochondria (2013) (12)
- Targeted tissue perfusion versus macrocirculation-guided standard care in patients with septic shock (TARTARE-2S): study protocol and statistical analysis plan for a randomized controlled trial (2016) (12)
- Do different anesthesia regimes affect hippocampal apoptosis and neurologic deficits in a rodent cardiac arrest model? (2015) (12)
- Definition and detection of alarms in critical care. (1996) (12)
- Respiratory changes after open-heart surgery (2005) (12)
- Immediate enteral feeding after abdominal surgery. (1985) (11)
- Costs and Resource Utilization in Intensive Care (1997) (11)
- Assessment of Systemic and Regional Oxygen Delivery and Consumption (1993) (11)
- Effect of site of lactate infusion on regional lactate exchange in pigs. (2010) (11)
- Effect of carnitine loading on long-chain fatty acid oxidation, maximal exercise capacity, and nitrogen balance (2005) (11)
- Postoperative parenteral nutrition with high supply of branched-chain amino acids: effects on nitrogen balance and liver protein synthesis. (1986) (11)
- Repetitive synchronized cyclical oscillations of multisystem parameters subsequent to high-dose thiopental therapy for status epilepticus secondary to herpes encephalitis. (2000) (11)
- 37th International Symposium on Intensive Care and Emergency Medicine (part 1 of 3) (2017) (11)
- Systemic and regional pCO2 gradients as markers of intestinal ischaemia (1998) (11)
- 37th International Symposium on Intensive Care and Emergency Medicine (part 1 of 3) (2017) (11)
- Branched-chain and mixed amino acid solutions and thermogenesis in postoperative patients. (1994) (10)
- Erratum to: 36th International Symposium on Intensive Care and Emergency Medicine (2016) (10)
- The assessment of a data management system for critical care (1988) (10)
- Blood Flow and Adrenergic Drugs in Septic Shock (1991) (10)
- Left ventricular torsion abnormalities in septic shock and corrective effect of volume loading: a pilot study. (2013) (10)
- Physiological effects of reduced tidal volume at constant minute ventilation and inspiratory flow rate in acute respiratory distress syndrome (1996) (10)
- Increased splanchnic oxygen extraction because of routine nursing procedures* (2009) (10)
- Of delirium and sedation. (2014) (10)
- ARDS. Monitoring tissue perfusion. (2002) (10)
- Regional contribution to hypermetabolism following trauma. (1997) (10)
- Hypermetabolism and increased peripheral release of amino acids after subarachnoidal hemorrhage and its operative treatment. (1996) (10)
- Nutrition and body composition in multiple organ failure. (1995) (10)
- Effects of Lung Recruitment Maneuvers on Splanchnic Organ Perfusion During Endotoxin-Induced Pulmonary Arterial Hypertension (2010) (10)
- Forced fluid removal in critically ill patients with acute kidney injury (2012) (10)
- TONOMETRY REVISITED: PERFUSION-RELATED, METABOLIC, AND RESPIRATORY COMPONENTS OF GASTRIC MUCOSAL ACIDOSIS IN ACUTE CARDIORESPIRATORY FAILURE (2007) (10)
- Neural control of ventilation prevents both over-distension and de-recruitment of experimentally injured lungs (2017) (10)
- Splanchnic Vasoregulation After Major Abdominal Surgery in Pigs (2010) (9)
- Arterial blood pressure targets in septic shock: is it time to move to an individualized approach? (2015) (9)
- Patterns of energy expenditure in intensive-care patients. (1993) (9)
- The effect of dopexamine on regional tissue oxygenation, systemic inflammation and amino acid exchange in major abdominal surgery (2000) (9)
- Norepinephrine-induced hypertension dilates vasospastic basilar artery after subarachnoid haemorrhage in rabbits (2009) (9)
- Nitrogen and energy balance in depleted patients undergoing major gastrointestinal surgery: response to TPN. (1991) (9)
- The native cardiac output in human sepsis: a systematic review. (2016) (9)
- Accelerated splanchnic amino acid uptake after cardiac surgery. (1998) (9)
- Brain herniation in a patient with apparently normal intracranial pressure: a case report (2010) (9)
- Experimental carnitine depletion in rats. (1991) (9)
- Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: a study protocol for a randomised controlled trial (2016) (8)
- [Management of burn injuries]. (1996) (8)
- Preoperative glutamine loading does not prevent endotoxemia in cardiac surgery (1997) (8)
- Nutritional and metabolic effects of enteral and parenteral feeding in severely injured patients (1987) (8)
- Gastric tonometry after subarachnoid hemorrhage (2001) (8)
- Splanchnic hemodynamics in critical illness (2000) (8)
- EFFECTS OF LOW ABDOMINAL BLOOD FLOW AND DOBUTAMINE ON BLOOD FLOW DISTRIBUTION AND ON THE HEPATIC ARTERIAL BUFFER RESPONSE IN ANAESTHETIZED PIGS (2006) (8)
- Highs and lows in high-risk surgery: the controversy of goal-directed haemodynamic management (2005) (8)
- Interference of angiotensin II and enalapril with hepatic blood flow regulation. (2014) (8)
- Nutrition and Metabolism in Acute Respiratory Failure (1993) (8)
- The Immediate and Sustained Effects of Volume Challenge on Regional Blood Flows in Pigs (2008) (8)
- Urinary excretion of polyamines in patients with surgical and accidental trauma: effect of total parenteral nutrition. (1993) (8)
- Regional Blood Flow and Oxygen Transport in Patients with Low Cardiac Output Syndrome after Cardiac Surgery (1994) (7)
- Target blood pressure in sepsis: between a rock and a hard place (2013) (7)
- Physical and occupational therapy during sedation stops (2009) (7)
- Membrane microdialysis: Evaluation of a new method to assess splanchnic tissue metabolism* (2006) (7)
- Hypophosphatemia in Hypercatabolic Patients (1985) (7)
- CHANGES IN WHOLE BODY AND TISSUE OXYGEN CONSUMPTION DURING RECOVERY FROM HYPOTHERMIA : EFFECT OF AMINO ACID INFUSION (1991) (7)
- Different Contribution of Splanchnic Organs to Hyperlactatemia in Fecal Peritonitis and Cardiac Tamponade (2013) (7)
- Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients. (2014) (7)
- Gas exchange calculation may estimate changes in pulmonary blood flow during veno-arterial extracorporeal membrane oxygenation in a porcine model (2020) (7)
- Physiological effects and safety of an early, combined endurance and resistance training in mechanically ventilated, critically ill patients (2015) (7)
- Monitoring Tissue Perfusion (2002) (7)
- Effect of endotoxin, dobutamine and dopamine on muscle mitochondrial respiration in vitro. (2006) (7)
- Non-conventional vasopressors in septic shock: effects on hepatosplanchnic blood flow. (2000) (7)
- Nutrition status, severity of illness, and thermogenic response to parenteral nutrition. (1993) (7)
- Changes in whole body and tissue oxygen consumption during recovery from hypothermia: Effect of amino acid infusion (1991) (6)
- The association between early hemodynamic variables and outcome in normothermic comatose patients following cardiac arrest (2010) (6)
- Effect of food restriction on tissue carnitine concentration in rats. (1991) (6)
- Postoperative Splanchnic Blood Flow Redistribution in Response to Fluid Challenges in the Presence and Absence of Endotoxemia in a Porcine Model (2012) (6)
- The Effects of Fentanyl on Hepatic Mitochondrial Function (2016) (6)
- Does fluid loading influence measurements of intestinal permeability? (2005) (6)
- Nutrition support in trauma and sepsis. (2001) (6)
- Oxygen transport in septic shock. (1992) (6)
- Impact of a Potassium-enriched, Chloride-depleted 5% Glucose Solution on Gastrointestinal Function after Major Abdominopelvic Surgery: Results of a Randomized Controlled Trial (2016) (6)
- Metabolic response to experimental trauma: the time relation of post-traumatic protein metabolism. (1985) (6)
- Aggressive and moderate fluid resuscitation in septic pigs: consequences on morbidity (2007) (5)
- Does the anesthetic method influence the postoperative breathing pattern and gas exchange in hip surgery? A comparison between general and spinal anesthesia (1992) (5)
- CO(2)-Dependent vasomotor reactivity of cerebral arteries in patients with severe traumatic brain injury: time course and effect of augmentation of cardiac output with dobutamine. (2012) (5)
- The Role of Hypoxia and Inflammation in the Expression and Regulation of Proteins Regulating Iron Metabolism (2008) (5)
- The rabbit blood-shunt model for the study of acute and late sequelae of subarachnoid hemorrhage: technical aspects. (2014) (5)
- Polyamine excretion in depleted patients with gastrointestinal malignancy: effect of perioperative nutrition and tumor removal. (1992) (5)
- Esophageal versus surface recording of diaphragm compound muscle action potential (2015) (5)
- Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients – study protocol for a randomized controlled trial (2018) (5)
- Contribution of perfusion-related, metabolic and respiratory components to gastric mucosal acidosis in acute cardiorespiratory failure (2006) (5)
- Nutrition in acute renal failure. (1987) (5)
- Breathing pattern and gas exchange in emergency and elective abdominal surgical patients (1995) (4)
- The effect of sedation on weaning following coronary artery bypass grafting: propofol versus oxycodone‐thiopental (2000) (4)
- Impaired utilization of exogenous amino acids after surgery for subarachnoid haemorrhage (2005) (4)
- FAILURE OF ENALAPRILAT TO REDUCE BLOOD PRESSURE IN HYPERTENSIVE CARDIAC SURGERY PATIENTS (1995) (4)
- Changes in mitochondrial enzymatic activities of monocytes during prolonged hypobaric hypoxia and influence of antioxidants: A randomized controlled study (2015) (4)
- Gastrointestinal Impedance Spectroscopy to Detect Hypoperfusion During Hemorrhage (2017) (4)
- Correction: Effect of Remifentanil on Mitochondrial Oxygen Consumption of Cultured Human Hepatocytes (2012) (4)
- Effects of cardiac preload reduction and dobutamine on hepatosplanchnic blood flow regulation in porcine endotoxemia. (2012) (4)
- Total plasma clearance of intravenous essential amino acids: evidence of abnormal metabolism of amino acids in chronic renal failure. (1983) (4)
- Tracheal tear and tension pneumothorax complicating bronchoscopy-guided percutaneous tracheostomy. (2006) (4)
- Comparison of two long-chain triglyceride fat emulsions in parenteral nutrition of critically ill patients (1989) (4)
- Stable Glucose Balance in Premature Infants with Fluid Restriction and Early Enteral Feeding (1987) (4)
- Branched-chain amino acids in surgically stressed patients (1983) (4)
- Total parenteral nutrition in experimental uremia: studies of acute and chronic renal failure in the growing rat. (1984) (3)
- Differential effects of sepsis and trauma on urinary excretion of polyamines. (1993) (3)
- Correction to: Effects of hemodynamic monitoring using a single-use transesophageal echocardiography probe in critically ill patients – study protocol for a randomized controlled trial (2018) (3)
- Comparison of monoglyceryl acetoacetate and glucose as parental energy substrate after experimental trauma. (1986) (3)
- Lactate, Lactate/Pyruvate Ratio, Low Tissue Perfusion and Outcome (2001) (3)
- Experimental validation of a mean systemic pressure analog against zero-flow measurements in porcine VA-ECMO. (2022) (3)
- Measurement of tissue oxygen tension: Comparison between two subcutaneous oxygen tonometers (1991) (3)
- Changes in Left Ventricular Torsion Early Postoperatively After Aortic Valve Replacement and at Long-Term Follow-up. (2015) (3)
- Failure of additional ketoanalogues of branched chain amino acids to improve the response to parenteral nutrition after experimental trauma in the rat. (1985) (3)
- Thermodilution and esophageal Doppler ultrasound in the assessment of blood flow changes induced by endotoxin and dobutamine. (2008) (3)
- INVERSE THERMODILUTION WITH CONVENTIONAL PULMONARY ARTERY CATHETERS FOR THE ASSESSMENT OF CEREBRAL, HEPATIC, RENAL, AND FEMORAL BLOOD FLOW (2009) (3)
- Preliminary results of an ICP-controlled subarachnoid hemorrhage rabbit model for the study of delayed cerebral vasospasm. (2011) (3)
- Peri-operative adrenocortical response to low-dose (1 microg) ACTH and relation to postoperative complications in patients undergoing elective abdominal surgery. (2009) (3)
- Carnitine status during prolonged total parenteral nutrition. (1993) (3)
- Neuroprotection with the P53-Inhibitor Pifithrin-&mgr; after Cardiac Arrest in a Rodent Model (2017) (3)
- Induction of hypoxia inducible factor 1α by Toll-like receptors in human dendritic cells (2008) (3)
- Prolonged impairment of cell-mediated immunity after major abdominal surgery in malnourished patients. (1983) (3)
- Defense mechanisms to increasing back pressure for hepatic oxygen transport and venous return in porcine fecal peritonitis. (2020) (3)
- Effect of endotoxin, dobutamine and dopamine on muscle mitochondrial respiration in vitro (2006) (3)
- Sedation level and prevalence of delirium: response to Brummel and Ely (2014) (3)
- Oxygen Consumption and Carbon Dioxide Production: Physiological Basis and Practical Application in Intensive Care (1997) (3)
- Parenteral nutrition increases polyamine excretion after trauma: a controlled study (1991) (3)
- Splanchnic perfusion in intensive care patients. (2000) (3)
- Regional venous–arterial CO2 to arterial–venous O2 content difference ratio in experimental circulatory shock and hypoxia (2020) (2)
- ESICM LIVES 2016: part two (2016) (2)
- Peripheral tissue energy metabolism during recovery from hypothermia after cardiopulmonary bypass: effect of amino-acid infusions. (1991) (2)
- Right ventricular stroke volume assessed by pulmonary artery pulse contour analysis (2020) (2)
- Comparison of dexmedetomidine with propofol/midazolam in sedation of long-stay intensive care patients: a prospective randomized, controlled, multicenter trial (2007) (2)
- Effects of volume resuscitation on hepatosplanchnic oxygen consumption, liver mitochondrial function and mortality in endotoxemia (2007) (2)
- Lipopolysaccharide induces mitochondrial dysfunction in rat cardiac microvascular endothelial cells (2011) (2)
- Correction to: Continual hemodynamic monitoring with a single-use transesophageal echocardiography probe in critically ill patients with shock: a randomized controlled clinical trial (2019) (2)
- Splanchnic blood flow and multiple organ failure. (1995) (2)
- Time‐ and dose‐related regional fluxes of tissue‐type plasminogen activator in anesthetized endotoxemic pigs (2007) (2)
- DOPEXAMINE INDUCES GASTRIC MUCDSAL ACIDOSIS DESPITE INCREASED SPLANCHNIC BLOOD FLOW AFTER CARDIAC SORCERY (1994) (2)
- Inhaled Nitric Oxide Treatment for Aneurysmal SAH Patients With Delayed Cerebral Ischemia (2022) (2)
- Letter to the Editor: Venous return and the physical connection between distribution of segmental pressures and volumes. (2020) (2)
- Effects of Trendelenburg position and increased airway pressure on hepatic regional blood flow of normal and resected liver. (2020) (2)
- Mortality prediction in intensive care units including premorbid functional status improved performance and internal validity. (2021) (2)
- Tissue oxygenation – circulatory aspects (1997) (2)
- Nutritional support in the critically ill: introduction. (1997) (2)
- Night-time intensivists - waste of resources or failure of process optimization? (2013) (2)
- Splanchnic region is the main source of hypermetabolism in septic respiratory failure (1991) (2)
- Incidence of Vasospasm, Outcome, and Quality of Life after Endovascular and Surgical Treatment of Ruptured Intracranial Aneurysms: Results of a Single-Center Prospective Study in Switzerland (2011) (2)
- Perioperative Fluid Accumulation Impairs Intestinal Contractility to a Similar Extent as Peritonitis and Endotoxemia (2017) (2)
- Decontamination of Extracorporeal Membrane Oxygenator Devices With an Intensified Disinfection Protocol: How Strict Is Too Strict? (2018) (2)
- Vasoactive drugs and splanchnic perfusion in septic shock. (1998) (2)
- Neurally adjusted ventilatory assistance in patients with critical illness polyneuromyopathy (2009) (1)
- Intraperitoneal microdialysis: critique of an editorial. (2007) (1)
- Mechanical Ventilation in ARDS: Interaction of Respiratory Mechanics and Gas Exchange (1995) (1)
- Survival is not Enough: Quality of Life After Intensive Care (1999) (1)
- Hemodynamic and mitochondrial effects of enalapril in experimental sepsis (2013) (1)
- Should Vasopressors Be Started Early in Septic Shock? (2021) (1)
- Polyamine metabolism in high risk patients undergoing major abdominal operation. (1997) (1)
- Alanyl-glutamine infusion does not reduce nitrogen loss after surgical treatment of subarachnoidal hemorrhage (1993) (1)
- Carotid blood flow is correlated with cardiac output but not with arterial blood pressure in porcine fecal peritonitis (2011) (1)
- Nutrient pattern analysis in critically ill patients using Omics technology (NAChO) – Study protocol for a prospective observational study (2019) (1)
- Dexmedetomidine and Propofol Sedation in Critically Ill Patients and Dose Associated 90-day Mortality: A Secondary Cohort Analysis of a Randomized Controlled Trial (SPICE-III). (2022) (1)
- The new sepsis/septic shock‐3 definition is just not enough – more detailed research is needed (2016) (1)
- Lipid Peroxidation Products and Antioxidant Capacity in Portal Venous and Systemic Arterial Plasma during Gradual Intestinal Ischemia and Reperfusion in Pigs (1998) (1)
- Effects of lipopolysaccharide on isolated muscle mitochondrial respiration are dose and time dependent (2010) (1)
- P106 Methodological issues for the determination of mean systemic filling pressure at the end of life (2017) (1)
- Perioperative alanyl-glutamine does not prevent endotoxemia after coronary by-pass (1993) (1)
- Measuring Carbon Dioxide Tension in Saline (1995) (1)
- Growth failure due to uremia and congenital nephrosis: growth enhancement by aggressive nutritional therapy. (1982) (1)
- Reply to "Is the Guytonian framework justified in explaining heart lung interactions?" and "Venous return, mean systemic pressure and getting the right answer for the wrong reason". (2019) (1)
- Reconsidering the Logic of WFNS Grading in Patients with Severe Subarachnoid Hemorrhage (2014) (1)
- Parenteral nutrition in anuria of infancy: evidence for sustained net protein synthesis. (1983) (1)
- How to investigate regional blood flow (1996) (1)
- Impact of cardiac surgery and neurosurgery patients on variation in severity-adjusted resource use in intensive care units. (2022) (1)
- Apparent heterogenity in splanchnic vascular response to norepinephrine during sepsis (2007) (1)
- 0356. Effect of the neuroprotective p53-inhibitor pifithrin-µ in a rodent cardiac arrest model (2014) (0)
- Aspects of nitrogen metabolism and nutrition in acute and chronic renal failure with specific reference to growth (1985) (0)
- Automated Estimation of Adequate Unloading with Neurally Adjusted Ventilatory Assist (2011) (0)
- Poster Discussions (2011) (0)
- Monitoring and Management of Nutrition in an Automated Data Management System for Intensive Care (1989) (0)
- Preserved cerebral function after resuscitation and induction of hypothermia with packed snow (2010) (0)
- Twenty-four-hour neurally adjusted ventilatory assist and volume cycled ventilation have similar effects on respiratory neuromuscular function in a porcine model of fecal peritonitis (2010) (0)
- P108 Right atrial pressure as back-pressure to venous return (2017) (0)
- Involvement of mitochondrial ATP-sensitive K+ channels in fentanyl-induced mitochondrial dysfunction of cultured human hepatocytes (2013) (0)
- A prospective study on Terson’s syndrome and intraocular infections in critically ill patients (2013) (0)
- CARING FOR THE CRITICALLY ILL PATIENT Dexmedetomidine vs Midazolam or Propofol for SedationDuringProlongedMechanicalVentilation Two Randomized Controlled Trials (2012) (0)
- Is lactate clearance impaired in septic shock? (2015) (0)
- Oxygen transport in the critically ill. (2016) (0)
- Decision Support Systems in Intensive Care (1992) (0)
- Variation in Severity-Adjusted Resource use and Outcome for Neurosurgical Emergencies in the Intensive Care Unit. (2023) (0)
- P34-10 Muscle velocity recovery cycles in critical illness myopathy (2010) (0)
- Iconography : ARDS: Monitoring tissue perfusion (2011) (0)
- Interactions of nutrition and ventilation. (1993) (0)
- Comments on Teboul and Scheeren: understanding the Haldane effect (2017) (0)
- Impact of hepatic venous oxygen efflux and carotid blood flow on the difference between mixed and central venous oxygen saturation (2011) (0)
- IN VITRO TIME AND DOSE EFFECT OF LIPOPOLYSACCHA-RIDE ON THE MITOCHONDRIAL RESPIRATORY FUNCTION: 493 (2004) (0)
- HEPATOSPLANCHNIC OXYGEN KINETICS DURING ISOLATED ABDOMINAL AORTIC LOW FLOW: 320 (2002) (0)
- 7. Early muscle membrane dysfunction in porcine peritonitis (2011) (0)
- Endotoxin-induced activation of hypoxia-inducible factor 1α in cultured human hepatocytes and monocytes: impact on cellular and mitochondrial respiration (2008) (0)
- [Applications of parenteral nutrition]. (1980) (0)
- Intra- and postoperative oxygen transport in cardiac surgery: Association with postoperative complications (1994) (0)
- Severe Vascular Complications of Central Venous Line Placement (2011) (0)
- Expiratory flow limitation after open heart surgery (2005) (0)
- A-233 Xenon anaesthesia for hypoxic treatment of pancreatic cancer (2009) (0)
- Positive central-mixed venous oxygen saturation gradients: high oxygen saturation in the inferior vena cava confirms high splanchnic oxygen extraction (2011) (0)
- Poster Discussions (2011) (0)
- Arguments for the use of thermal indicators to measure whole body blood flow (1997) (0)
- Reply: Is the glass of delirium half full or half empty? (2014) (0)
- Poster Discussions (2011) (0)
- Norepinephrine versus angiotensin II in septic shock: effects on isolated kidney, heart and liver mitochondrial respiration (2012) (0)
- Intestinal mucosal microdialysis: Histamine release in splanchnic ischemia/reperfusion injury in piglets (1996) (0)
- Splanchnic blood flow and blood volume are highly variable in critically ill patients, depending on the underlying disease, compensatory mechanisms, and therapeutic interventions. During low blood flow states or hypoxemia, adaptive mecha- (0)
- Should traditional signs of hypovolemia trigger fluid administration after major abdominal surgery (2006) (0)
- Research Does fluid loading influence measurements of intestinal (2005) (0)
- Collapsibility of caval vessels and right ventricular afterload: decoupling of stroke volume variation from preload during mechanical ventilation. (2021) (0)
- Effect of nutrition on ventilatory demand (1991) (0)
- Vasoactive Drugs and Splanchnic Perfusion (1996) (0)
- MONITORING SEDATION: DIFFERENT EFFECTS OF DEXMEDETOMIDINE/REMIFENTANIL AND MIDAZOLAM/REMIFENTANIL ON EVENT-RELATED POTENTIALS IN VOLUNTEERS: 374 (2004) (0)
- EFFECTS OF ANAESTHESIA AND MAJOR ABDOMINAL SURGERY ON MITOCHONDRIAL RESPIRATION: 197 (2004) (0)
- Assessment of splanchnic tissue perfusion. (1995) (0)
- Free Papers (2017) (0)
- Flow motion in the jejunal mucosa is present during normal and moderately but not severely reduced blood flow: A-230 (2004) (0)
- Medications for Sedation in Patients With Prolonged Mechanical Ventilation—Reply (2012) (0)
- 0353. Do the noble gases helium and argon exert neuroprotective effects in a rodent cardiac arrest model? (2014) (0)
- Noradrenaline for treatment of endotoxemic shock in pigs is associated with improved hepatic mitochondrial respiration (2008) (0)
- The Vascular Bed during Critical Illness: Evaluation in Animal Models (2006) (0)
- Non-CO2-insufflation and acute abdominal compartment during emergency endoscopy contributing to fatal outcome in advanced obstructive tumor of the gastro-esophageal junction with severe bleeding (2015) (0)
- Functional Consequence Of TLR2- And TLR4-Induced Activation Of HIF-1± On Maturation Of Human Dendritic Cells (2010) (0)
- O.30 Reduced excretion of N8-acetylspermidinebefore death in prolonged intensive care — failure of cellular metabolism (1995) (0)
- Tidal volume in acute respiratory distress syndrome (1996) (0)
- Intracranial-Pressure-Controlled Rabbit Subarachnoid Hemorrhage Model for the Study of Early Brain Injury (2011) (0)
- Splanchnic Blood Flow (1997) (0)
- Free Papers (2011) (0)
- Interpretation of Changes in Regional and Mucosal PCO2 Gradients: The Haldane Effect (2000) (0)
- Metabolic Stress and Dobutamine (1996) (0)
- Effects of Pharmacologic Agents on Splanchnic Blood Flow (1996) (0)
- Free Papers (2011) (0)
- Biatrial enlargement: 6,000 ml intracardiac blood volume (2014) (0)
- Subcellular Energetics and Metabolism: A Cross-Species Framework. (2017) (0)
- Intraperitoneal microdialysis : Critique of an editorial. Commentary (2007) (0)
- Acute/Chronic respiratory failure III (2011) (0)
- Effect of bacterial load versus duration of exposure to bacteria on plasma TNFα concentrations in porcine fecal peritonitis (2011) (0)
- Assessment of muscle membrane properties using muscle velocity recovery cycles in patients with critical illness polyneuromyopathy (2009) (0)
- Acute/Chronic respiratory failure (1992) (0)
- A-230 Flow motion in the jejunal mucosa is present during normal and moderately but not severely reduced blood flow (2009) (0)
- Regional oxygen consumption in sepsis and after surgery: effects of endotoxemia and increased blood levels of TNF (1992) (0)
- Muscle versus liver mitochondrial respiration in experimental three-hit endotoxemia (2007) (0)
- Prediction model of hospital mortality for patients treated in intensive care units: validation with focus on geographical and temporal transportability (2021) (0)
- Liver in carnitine metabolism. (1997) (0)
- Intracerebral hemorrhage in ICU: is it worth treating? (2016) (0)
- Case report Delayed heart perforation after blunt trauma (2002) (0)
- Contributors to Differences between Mixed and Central Venous Oxygen Saturation (2018) (0)
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