Julian Little
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Researcher ORCID ID = 0000-0001-5026-5531
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(Suggest an Edit or Addition)Julian Little's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Genome-wide association studies for complex traits: consensus, uncertainty and challenges (2008) (2939)
- Cleft lip and palate (2009) (849)
- Assessment of cumulative evidence on genetic associations: interim guidelines. (2008) (559)
- Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE statement (2009) (494)
- STrengthening the REporting of Genetic Association Studies (STREGA)— An Extension of the STROBE Statement (2009) (482)
- Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17. (1994) (477)
- Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. (2004) (464)
- Daily soluble aspirin and prevention of colorectal adenoma recurrence: one-year results of the APACC trial. (2003) (404)
- Reporting, appraising, and integrating data on genotype prevalence and gene-disease associations. (2002) (395)
- Tobacco smoking and oral clefts: a meta-analysis. (2004) (390)
- Disruption of an AP-2α binding site in an IRF6 enhancer is strongly associated with cleft lip (2008) (355)
- Glutathione S-transferase polymorphisms and colorectal cancer: a HuGE review. (2000) (320)
- Epidemiology and control of neural tube defects (1993) (287)
- Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: case-control study of subjects participating in the Nottingham faecal occult blood screening programme. (1993) (281)
- Prevalence at Birth of Cleft Lip with or without Cleft Palate: Data from the International Perinatal Database of Typical Oral Clefts (IPDTOC) (2011) (275)
- A road map for efficient and reliable human genome epidemiology (2006) (252)
- Vitamin D status of Canadians as measured in the 2007 to 2009 Canadian Health Measures Survey. (2010) (226)
- Long term health and neurodevelopment in children exposed to antiepileptic drugs before birth (2002) (224)
- Rural and urban differences in stage at diagnosis of colorectal and lung cancers (2001) (215)
- How many genes underlie the occurrence of common complex diseases in the population? (2005) (197)
- Addressing the challenges of cleft lip and palate research in India (2009) (177)
- Systematic Reviews of Genetic Association Studies (2009) (176)
- Epidemiology of Childhood Cancer (1999) (175)
- Folate intake, markers of folate status and oral clefts: is the evidence converging? (2008) (166)
- Rural factors and survival from cancer: analysis of Scottish cancer registrations (2000) (165)
- Quantifying realistic sample size requirements for human genome epidemiology (2008) (163)
- N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review. (2000) (156)
- Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies (2010) (154)
- Antioxidant intake and adult-onset wheeze: a case-control study. Aberdeen WHEASE Study Group. (1999) (153)
- DataSHIELD: resolving a conflict in contemporary bioscience—performing a pooled analysis of individual-level data without sharing the data (2010) (148)
- Identification of risk factors associated with onset and progression of amyotrophic lateral sclerosis using systematic review and meta‐analysis (2017) (145)
- Genome-Wide Association Studies, Field Synopses, and the Development of the Knowledge Base on Genetic Variation and Human Diseases (2009) (144)
- Cytochrome P-450 1A1 gene polymorphisms and risk of breast cancer: a HuGE review. (2005) (134)
- On the synthesis and interpretation of consistent but weak gene-disease associations in the era of genome-wide association studies. (2007) (132)
- Folate and breast cancer: the role of polymorphisms in methylenetetrahydrofolate reductase (MTHFR). (2002) (128)
- An international case-control study of adult glioma and meningioma: the role of head trauma. (1998) (128)
- Systematic Review: Family History in Risk Assessment for Common Diseases (2009) (126)
- A network of investigator networks in human genome epidemiology. (2005) (121)
- Smoking and Orofacial Clefts: A United Kingdom–Based Case-Control Study (2004) (115)
- Associations between two common variants C677T and A1298C in the methylenetetrahydrofolate reductase gene and measures of folate metabolism and DNA stability (strand breaks, misincorporated uracil, and DNA methylation status) in human lymphocytes in vivo. (2004) (114)
- Impact of deprivation and rural residence on treatment of colorectal and lung cancer (2002) (113)
- The Emergence of Networks in Human Genome Epidemiology: Challenges and Opportunities (2007) (112)
- An epidemiologic assessment of genomic profiling for measuring susceptibility to common diseases and targeting interventions (2004) (111)
- Waterpipe smoking and cancer: systematic review and meta-analysis (2016) (110)
- Size matters: just how big is BIG? (2008) (108)
- CYP17 gene polymorphisms: prevalence and associations with hormone levels and related factors. a HuGE review. (2004) (106)
- Strengthening the reporting of genetic association studies (STREGA): an extension of the strengthening the reporting of observational studies in epidemiology (STROBE) statement. (2009) (105)
- Systematic meta-analyses and field synopsis of genetic association studies in colorectal cancer. (2012) (104)
- STrengthening the REporting of Genetic Association Studies (STREGA)—an extension of the STROBE statement (2009) (104)
- STrengthening the REporting of Genetic Association studies (STREGA) – an extension of the STROBE statement (2009) (103)
- Strengthening the reporting of genetic risk prediction studies: the GRIPS statement (2011) (101)
- Passive Smoking in the Etiology of Non-Syndromic Orofacial Clefts: A Systematic Review and Meta-Analysis (2015) (99)
- Mendelian randomisation: a new spin or real progress? (2003) (98)
- The emergence of epidemiology in the genomics age. (2004) (98)
- Antioxidant intake and adult-onset wheeze: a case–control study (1999) (96)
- Psychological effects of a low-grade abnormal cervical smear test result: anxiety and associated factors (2006) (94)
- Systematic review of epidemiological studies on meat, dairy products and egg consumption and risk of colorectal adenomas. (2000) (93)
- After-effects reported by women following colposcopy, cervical biopsies and LLETZ: results from the TOMBOLA trial. (2009) (90)
- Human Genome Epidemiology: A Scientific Foundation for Using Genetic Information to Improve Health and Prevent Disease (2003) (89)
- Is rigorous retrospective harmonization possible? Application of the DataSHaPER approach across 53 large studies. (2011) (88)
- MC1R variants increased the risk of sporadic cutaneous melanoma in darker‐pigmented Caucasians: A pooled‐analysis from the M‐SKIP project (2014) (86)
- Prevention by daily soluble aspirin of colorectal adenoma recurrence: 4-year results of the APACC randomised trial (2011) (86)
- The Role of Cytokine Gene Polymorphisms in Colorectal Cancer and Their Interaction with Aspirin Use in the Northeast of Scotland (2004) (83)
- Folate, DNA stability and colo-rectal neoplasia (2004) (82)
- Identifying key knowledge needs for evidence‐based conservation of wild insect pollinators: a collaborative cross‐sectoral exercise (2013) (82)
- Effect of Folic Acid Food Fortification in Canada on Congenital Heart Disease Subtypes (2016) (81)
- Dietary flavonoid intake and colorectal cancer: a case–control study (2009) (81)
- Family history and improving health. (2009) (79)
- Parental exposure to polycyclic aromatic hydrocarbons and the risk of childhood brain tumors: The SEARCH International Childhood Brain Tumor Study. (2004) (79)
- Defining the genetic susceptibility to cervical neoplasia—A genome-wide association study (2017) (78)
- Socioeconomic status and orofacial clefts in Scotland, 1989 to 1998. (2003) (78)
- Colorectal adenomas and diet: a case-control study of subjects participating in the Nottingham faecal occult blood screening programme. (1993) (77)
- Cytological surveillance compared with immediate referral for colposcopy in management of women with low grade cervical abnormalities: multicentre randomised controlled trial (2009) (76)
- Genomic cloud computing: legal and ethical points to consider (2014) (75)
- Parental occupations and childhood brain tumors: results of an international case–control study (2001) (75)
- A qualitative study of provider perspectives of structural barriers to cervical cancer screening among first nations women. (2013) (72)
- Strengthening the reporting of genetic association studies (STREGA): an extension of the STROBE Statement (2009) (71)
- Data Safe Havens in health research and healthcare (2015) (68)
- Occupational risk factors for low grade and high grade glioma: Results from an international case control study of adult brain tumours (2005) (67)
- The human genome project is complete. How do we develop a handle for the pump? (2003) (66)
- Trial of management of borderline and other low-grade abnormal smears (TOMBOLA): Trial design. (2006) (63)
- Colorectal cancer and genetic polymorphisms of CYP1A1, GSTM1 and GSTT1: A case‐control study in the Grampian region of Scotland (2006) (62)
- Colorectal adenomas and energy intake, body size and physical activity: a case-control study of subjects participating in the Nottingham faecal occult blood screening programme. (1993) (62)
- Human genome epidemiologic reviews: the beginning of something HuGE. (2000) (61)
- Cancer Risk in Children and Adolescents with Birth Defects: A Population-Based Cohort Study (2013) (61)
- Lifestyle and socio-demographic factors associated with high-risk HPV infection in UK women (2007) (59)
- Relation of childhood brain tumors to exposure of parents and children to tobacco smoke: The Search international case‐control study (2002) (57)
- Global Oral Health Inequalities (2011) (56)
- Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer: a case–control study in a population with relatively low folate intake (2008) (56)
- Systematic review of cancer treatment programmes in remote and rural areas (1999) (55)
- Exposure to passive smoking during pregnancy and childhood, and cancer risk: the epidemiological evidence. (1994) (54)
- A Meta-Analysis of Observational Studies of the Association Between Chronic Occupational Exposure to Lead and Amyotrophic Lateral Sclerosis (2014) (54)
- Vitamin D receptor (VDR) polymorphisms and severe RSV bronchiolitis: A systematic review and meta‐analysis (2014) (53)
- Colon cancer and genetic variation in folate metabolism: the clinical bottom line. (2003) (52)
- Biopsy and selective recall compared with immediate large loop excision in management of women with low grade abnormal cervical cytology referred for colposcopy: multicentre randomised controlled trial (2009) (52)
- Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration (2011) (50)
- An international case-control study of adult diet and brain tumor risk: a histology-specific analysis by food group. (2009) (50)
- The adenoma-carcinoma sequence and prospects for the prevention of colorectal neoplasia. (1996) (50)
- Systematic review of statistical approaches to quantify, or correct for, measurement error in a continuous exposure in nutritional epidemiology (2017) (50)
- Prenatal vitamin supplementation and risk of childhood brain tumors (1998) (49)
- Folic acid supplementation use and the MTHFR C677T polymorphism in orofacial clefts etiology: An individual participant data pooled-analysis. (2013) (48)
- MC1R variants as melanoma risk factors independent of at-risk phenotypic characteristics: a pooled analysis from the M-SKIP project (2018) (48)
- The utility and predictive value of combinations of low penetrance genes for screening and risk prediction of colorectal cancer (2010) (47)
- Risk factors for adult onset wheeze: a case control study. (1998) (47)
- Factors associated with psychological distress following colposcopy among women with low‐grade abnormal cervical cytology: a prospective study within the Trial Of Management of Borderline and Other Low‐grade Abnormal smears (TOMBOLA) (2011) (47)
- Metabolomics of prematurity: analysis of patterns of amino acids, enzymes, and endocrine markers by categories of gestational age (2014) (46)
- Socioeconomic Status and Orofacial Clefts in Scotland, 1989 to 1998 (2003) (46)
- Methods for meta-analyses of genome-wide association studies: critical assessment of empirical evidence. (2012) (45)
- Recommendations and proposed guidelines for assessing the cumulative evidence on joint effects of genes and environments on cancer occurrence in humans. (2012) (45)
- A simple model to predict risk of gestational diabetes mellitus from 8 to 20 weeks of gestation in Chinese women (2019) (45)
- Developing a questionnaire to measure the psychosocial impact of an abnormal cervical smear result and its subsequent management: the TOMBOLA (Trial Of Management of Borderline and Other Low-grade Abnormal smears) trial (2005) (44)
- Gene–environment interactions and colorectal cancer risk: An umbrella review of systematic reviews and meta‐analyses of observational studies (2019) (43)
- SEARCH international case-control study of childhood brain tumours: role of index pregnancy and birth, and mother's reproductive history. (1999) (42)
- Translating rare-disease therapies into improved care for patients and families: what are the right outcomes, designs, and engagement approaches in health-systems research? (2015) (42)
- Options for managing low grade cervical abnormalities detected at screening: cost effectiveness study (2009) (42)
- Stroke and Cerebrovascular Disease in Pregnancy: Incidence, Temporal Trends, and Risk Factors (2019) (41)
- Citizens’ Values Regarding Research With Stored Samples From Newborn Screening in Canada (2012) (40)
- Folate and Clefts of the Lip and Palate—A U.K.-Based Case-Control Study: Part II: Biochemical and Genetic Analysis (2008) (40)
- Characteristics and Workload of Pediatricians in China (2019) (39)
- The HuGENetTM HuGE Review Handbook, version 1.0 (2006) (39)
- MC1R gene variants and non-melanoma skin cancer: a pooled-analysis from the M-SKIP project (2015) (38)
- Accurate prediction of gestational age using newborn screening analyte data. (2016) (37)
- Strengthening the reporting of genetic risk prediction studies: the GRIPS statement. (2011) (37)
- Experiences of caregivers of children with inherited metabolic diseases: a qualitative study (2016) (36)
- Antenatal therapeutic drug exposure and fetal/neonatal tumours: review of 89 cases. (1998) (36)
- Folate and Clefts of the Lip and Palate—A U.K.-Based Case-Control Study: Part I: Dietary and Supplemental Folate (2008) (36)
- Public views on participating in newborn screening using genome sequencing (2014) (36)
- Human exposure to environmental contaminants and congenital anomalies: a critical review (2017) (36)
- Intermediate CAG Repeat Expansion in the ATXN2 Gene Is a Unique Genetic Risk Factor for ALS−A Systematic Review and Meta-Analysis of Observational Studies (2014) (36)
- Prevention of Orofacial Clefts: Does Pregnancy Planning Have a Role? (2007) (36)
- Results from an international case-control study of childhood brain tumors: the role of prenatal vitamin supplementation. (1998) (35)
- When to replicate systematic reviews of interventions: consensus checklist (2020) (34)
- The Epidemiologic Approach to Pharmacogenomics (2005) (33)
- Bias in the case-only design applied to studies of gene-environment and gene-gene interaction: a systematic review and meta-analysis. (2011) (33)
- Achieving the “triple aim” for inborn errors of metabolism: a review of challenges to outcomes research and presentation of a new practice-based evidence framework (2012) (32)
- Understanding sickle cell carrier status identified through newborn screening: a qualitative study (2010) (31)
- Informing Parents About Expanded Newborn Screening: Influences on Provider Involvement (2009) (31)
- Alcohol consumption and the risk of breast cancer among BRCA1 and BRCA2 mutation carriers. (2010) (31)
- Community-randomised controlled trial embedded in the Anishinaabek Cervical Cancer Screening Study: human papillomavirus self-sampling versus Papanicolaou cytology (2016) (31)
- Systematic meta-analyses and field synopsis of genetic association studies in colorectal adenomas. (2016) (30)
- Strengthening the Reporting of Genetic Risk Prediction Studies: The GRIPS Statement (2011) (30)
- Variability in the clinical management of fatty acid oxidation disorders: results of a survey of Canadian metabolic physicians (2012) (30)
- Burkitt’s Lymphoma: a review of the epidemiology (2001) (30)
- Screening for depression in women during pregnancy or the first year postpartum and in the general adult population: a protocol for two systematic reviews to update a guideline of the Canadian Task Force on Preventive Health Care (2019) (30)
- A P3G Generic Access Agreement for Population Genomic Studies (2013) (30)
- Contacts with animals and humans as risk factors for adult brain tumours. An international case-control study. (2002) (29)
- Postnatal Prediction of Gestational Age Using Newborn Fetal Hemoglobin Levels (2016) (29)
- Child and family experiences with inborn errors of metabolism: a qualitative interview study with representatives of patient groups (2015) (28)
- The role of human papillomavirus testing in the management of women with low‐grade abnormalities: multicentre randomised controlled trial (2010) (28)
- Expectations and values about expanded newborn screening: a public engagement study (2015) (27)
- A high frequency of the MTHFR 677C>T polymorphism in Scottish women with epilepsy: Possible role in pathogenesis (2008) (26)
- Management of women with low grade cytology: how reassuring is a normal colposcopy examination? (2015) (26)
- Clinical obligations and public health programmes: healthcare provider reasoning about managing the incidental results of newborn screening (2009) (26)
- Consent for Newborn Screening: The Attitudes of Health Care Providers (2009) (25)
- Strategies for Increasing Cervical Cancer Screening Amongst First Nations Communities in Northwest Ontario, Canada (2016) (25)
- Association of maternal risk factors with the recent rise of neural tube defects in Canada (2019) (25)
- Who defaults from colposcopy? A multi-centre, population-based, prospective cohort study of predictors of non-attendance for follow-up among women with low-grade abnormal cervical cytology. (2012) (25)
- Turning the pump handle: evolving methods for integrating the evidence on gene-disease association. (2007) (23)
- The Unintended Consequences of Cervical Screening: Distress in Women Undergoing Cytologic Surveillance (2014) (23)
- Modes of delivery in preventive intervention studies: a rapid review (2014) (23)
- Cyclooxygenase-2 expression and recurrence of colorectal adenomas: effect of aspirin chemoprevention (2010) (22)
- Reporting genetic association studies: the STREGA statement (2009) (22)
- Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration (2011) (22)
- Comparison of diet history interview and self completed questionnaire in assessment of diet in an elderly population. (1990) (22)
- The use of relative incidence ratios in self-controlled case series studies: an overview (2016) (21)
- Public attitudes towards genomic risk profiling as a component of routine population screening. (2013) (21)
- Pediatric nurses' turnover intention and its association with calling in China's tertiary hospitals. (2020) (21)
- Determinants of neurological disease: Synthesis of systematic reviews (2017) (21)
- Low dose aspirin, COX-inhibition and chemoprevention of colorectal cancer. (2005) (21)
- Family History Tools in Primary Care: Does One Size Fit All? (2012) (21)
- Fetal anticonvulsant syndromes and polymorphisms in MTHFR, MTR, and MTRR (2007) (20)
- Genetic variation associated with the occurrence and progression of neurological disorders. (2017) (20)
- Folate intake, markers of folate status and oral clefts: An updated set of systematic reviews and meta‐analyses (2020) (20)
- Low radon exposures and lung cancer risk: joint analysis of the Czech, French, and Beaverlodge cohorts of uranium miners (2019) (20)
- Scoping review of patient- and family-oriented outcomes and measures for chronic pediatric disease (2015) (20)
- Epidemiology of neurodevelopmental disorders in children. (2000) (20)
- Public Perceptions of the Benefits and Risks of Newborn Screening (2015) (20)
- Family history, metabolic gene polymorphism, diet and risk of colorectal cancer. (1999) (20)
- STrengthening the REporting of Genetic Association studies (STREGA): an extension of the STROBE Statement. (2009) (19)
- Communicating in a public health crisis (2020) (19)
- Key characteristics of 86 agents known to cause cancer in humans (2019) (19)
- Newborn Bilirubin Screening for Preventing Severe Hyperbilirubinemia and Bilirubin Encephalopathy: A Rapid Review. (2017) (19)
- HLA and KIR Associations of Cervical Neoplasia (2018) (19)
- APACC, a French prospective study on aspirin efficacy in reducing colorectal adenoma recurrence: design and baseline findings (2001) (19)
- United Kingdom cervical cancer screening and the costs of time and travel (2007) (19)
- Long-term psychosocial impact of alternative management policies in women with low-grade abnormal cervical cytology referred for colposcopy: a randomised controlled trial (2010) (19)
- Dietary intake of folate and related micronutrients, genetic polymorphisms in MTHFR and colorectal cancer A population-based case-control study in Scotland (2002) (19)
- Prenatal vitamin supplementation and pediatric brain tumors: huge international variation in use and possible reduction in risk (1998) (19)
- Genetic Interactions in Nonsyndromic Orofacial Clefts in Europe—EUROCRAN Study (2017) (18)
- Relationship Between Adiposity and Pulmonary Function in School-Aged Canadian Children. (2014) (18)
- Family cancer history and risk of brain tumors in children: results of the SEARCH international brain tumor study (2008) (18)
- Refining the Management of Low-Grade Cervical Abnormalities in the UK National Health Service and Defining the Potential for Human Papillomavirus Testing: A Commentary on Emerging Evidence (2006) (18)
- Health-care providers’ views on pursuing reproductive benefit through newborn screening: the case of sickle cell disorders (2011) (18)
- Vitamin Supplementation in Pregnancy (1989) (17)
- Reduced risk of colorectal cancer among recent generations in New Zealand. (1992) (17)
- Breast Cancer Risk in Relation to Alcohol Consumption and BRCA Gene Mutations – A Case‐Only Study of Gene‐Environment Interaction (2011) (17)
- Human Papillomavirus Infection and Anxiety: Analyses in Women with Low-Grade Cervical Cytological Abnormalities Unaware of Their Infection Status (2011) (17)
- Strengthening the reporting of genetic risk prediction studies: the GRIPS statement (2011) (17)
- Concordance between sites of tumor development in humans and in experimental animals for 111 agents that are carcinogenic to humans (2019) (17)
- Using Community Engagement to Inform and Implement a Community-Randomized Controlled Trial in the Anishinaabek Cervical Cancer Screening Study (2013) (17)
- Systematic meta-analyses and field synopsis of genetic and epigenetic studies in paediatric inflammatory bowel disease (2016) (17)
- Psychosocial Impact of Alternative Management Policies for Low-Grade Cervical Abnormalities: Results from the TOMBOLA Randomised Controlled Trial (2013) (16)
- Segregation analysis of cleft lip with or without cleft palate in the First Nations (Amerindian) people of British Columbia and review of isolated cleft palate etiologies. (2009) (16)
- Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer (2019) (16)
- Clinical utility of cancer family history collection in primary care. (2009) (16)
- Maternal medication use and the risk of brain tumors in the offspring: The SEARCH international case‐control study (2006) (16)
- Association of Melanocortin-1 Receptor Variants with Pigmentary Traits in Humans: A Pooled Analysis from the M-Skip Project. (2016) (16)
- CYP 17 Gene Polymorphisms : Prevalence and Associations with Hormone Levels and Related Factors (2004) (16)
- Effectiveness of stop smoking interventions among adults: protocol for an overview of systematic reviews and an updated systematic review (2019) (15)
- CYP17 and breast cancer: no overall effect, but what about interactions? (2005) (15)
- Attitudes of undergraduate university women towards HPV vaccination: a cross-sectional study in Ottawa, Canada (2018) (15)
- External validation of postnatal gestational age estimation using newborn metabolic profiles in Matlab, Bangladesh (2019) (15)
- Evaluating LINE-1 methylation in cleft lip tissues and its association with early pregnancy exposures. (2018) (15)
- Bridging the gap between science and policy: an international survey of scientists and policy makers in China and Canada (2015) (14)
- Canada: Public Health Genomics (2008) (14)
- “They Should Be Asking Us”: A Qualitative Decisional Needs Assessment for Women Considering Cervical Cancer Screening (2018) (14)
- Pregnancy outcomes during the COVID-19 pandemic in Canada, March to August 2020. (2021) (14)
- Cell-Free DNA-Based Non-invasive Prenatal Screening for Common Aneuploidies in a Canadian Province: A Cost-Effectiveness Analysis. (2018) (14)
- Melanocortin-1 receptor, skin cancer and phenotypic characteristics (M-SKIP) project: study design and methods for pooling results of genetic epidemiological studies (2012) (14)
- Multigene panels in prostate cancer risk assessment: a systematic review (2015) (14)
- Postcolposcopy Management of Women With Histologically Proven CIN 1: Results From TOMBOLA (2014) (13)
- Engaging Canadian First Nations women in cervical screening through education (2016) (13)
- Leukaemia in young children living in the vicinity of nuclear power plants (2008) (12)
- Reporting of Systematic Reviews: The Challenge of Genetic Association Studies (2007) (12)
- Comparison of first‐tier cell‐free DNA screening for common aneuploidies with conventional publically funded screening (2017) (12)
- Which women default from follow‐up cervical cytology tests? A cohort study within the TOMBOLA trial (2012) (12)
- Screening for the prevention and early detection of cervical cancer: protocol for systematic reviews to inform Canadian recommendations (2020) (12)
- Impact of Dehydroepiandrosterone Sulfate on Newborn Leukocyte Telomere Length (2017) (12)
- Primary care role in expanded newborn screening: After the heel prick test. (2013) (11)
- Nonsyndromic cleft palate: An association study at GWAS candidate loci in a multiethnic sample. (2018) (11)
- Long-Term Worries after Colposcopy: Which Women Are at Increased Risk? (2015) (11)
- Colorectal neoplasia and genetic polymorphisms associated with folate metabolism (2002) (11)
- Strengthening the reporting of Genetic Risk Prediction Studies: the GRIPS statement. (2011) (10)
- After-effects reported by women having follow-up cervical cytology tests in primary care: a cohort study within the TOMBOLA trial. (2011) (10)
- Using Newborn Screening Bloodspots for Research: Public Preferences for Policy Options (2016) (10)
- Comparing alternative design options for chronic disease prevention interventions (2015) (10)
- Measuring the psychosocial burden in women with low-grade abnormal cervical cytology in the TOMBOLA trial: psychometric properties of the Process and Outcome Specific Measure (POSM) (2014) (10)
- Invited commentary: maternal effects in preterm birth--effects of maternal genotype, mitochondrial DNA, imprinting, or environment? (2009) (10)
- MC1R variants in childhood and adolescent melanoma: a retrospective pooled analysis of a multicentre cohort. (2019) (10)
- Editorial: Updated guidance on human genome epidemiology (HuGE) reviews and meta-analyses of genetic associations. (2014) (10)
- Asymptomatic Colorectal Neoplasia and Fecal Characteristics (2002) (10)
- A normal colposcopy examination fails to provide psychological reassurance for women who have had low‐grade abnormal cervical cytology (2015) (10)
- Health services use among children diagnosed with medium-chain acyl-CoA dehydrogenase deficiency through newborn screening: a cohort study in Ontario, Canada (2019) (9)
- Effects of fat mass and obesity-associated (FTO) gene polymorphisms on binge eating in women with binge-eating disorder: The moderating influence of attachment style. (2019) (9)
- Multigene panels in prostate cancer risk assessment. (2012) (9)
- Bronchial hyperresponsiveness and adult onset wheeze: the influence of atopy. (1999) (9)
- Strengthening the reporting of Genetic RIsk Prediction Studies: the GRIPS Statement. (2011) (9)
- Scientific reporting is suboptimal for aspects that characterize genetic risk prediction studies: a review of published articles based on the Genetic RIsk Prediction Studies statement. (2014) (9)
- Incidental screen positive findings in a prospective cohort study in Matlab, Bangladesh: insights into expanded newborn screening for low-resource settings (2019) (9)
- Folate, DNA stability and colo-rectal neoplasia. (2004) (8)
- Non‐invasive prenatal testing for the prenatal screening of sex chromosome aneuploidies: A systematic review and meta‐analysis of diagnostic test accuracy studies (2021) (8)
- Noninvasive Prenatal Testing for Trisomies 21, 18, and 13, Sex Chromosome Aneuploidies, and Microdeletions in Average-Risk Pregnancies: A Cost-Effectiveness Analysis. (2020) (8)
- Childhood cancer and neural tube defects. (1997) (8)
- Strengthening the reporting of genetic risk prediction studies: the GRIPS statement (2011) (8)
- Prospective head-to-head comparison of accuracy of two sequencing platforms for screening for fetal aneuploidy by cell-free DNA: the PEGASUS study (2019) (8)
- Evaluation of the quality of clinical data collection for a pan-Canadian cohort of children affected by inherited metabolic diseases: lessons learned from the Canadian Inherited Metabolic Diseases Research Network (2020) (7)
- Family History: Impact on Coronary Heart Disease Risk Assessment beyond Guideline-Defined Factors (2013) (7)
- Postnatal gestational age estimation via newborn screening analysis: application and potential (2019) (7)
- Teaching tools to engage Anishinaabek First Nations women in cervical cancer screening: Report of an educational workshop (2016) (7)
- Aspirin and other nonsteroidal antiinflammatory drugs and colorectal neoplasia. (1994) (7)
- Association between a common missense variant in LOXL3 gene and the risk of non‐syndromic cleft palate (2018) (7)
- Association between newborn screening analytes and hypoxic ischemic encephalopathy (2019) (7)
- Strengthening the reporting of genetic risk prediction studies: the GRIPS statement (2011) (7)
- Improving Social Justice in COVID-19 Health Research: Interim Guidelines for Reporting Health Equity in Observational Studies (2021) (7)
- On Track? Using the Human Genome Epidemiology Roadmap (2010) (6)
- Psychosocial morbidity in women with abnormal cervical cytology managed by cytological surveillance or initial colposcopy: longitudinal analysis from the TOMBOLA randomised trial (2016) (6)
- LINE-1 methylation in cleft lip tissues: Influence of infant MTHFR c.677C>T genotype. (2019) (6)
- Strengthening the Reporting of Genetic Risk Prediction Studies: The GRIPS Statement (2011) (6)
- Development and external validation of machine learning algorithms for postnatal gestational age estimation using clinical data and metabolomic markers (2020) (6)
- Metabolic profiles derived from residual blood spot samples: A longitudinal analysis (2018) (6)
- Effectiveness of individual‐focused interventions to prevent chronic disease (2014) (6)
- Assessment of systematic effects of methodological characteristics on candidate genetic associations (2013) (5)
- Health Care for Mitochondrial Disorders in Canada: A Survey of Physicians (2019) (5)
- Strengthening the reporting of genetic risk prediction studies: the GRIPS statement (2011) (5)
- A vision for chronic disease prevention and intervention research: Report from a workshop (2014) (5)
- Multivitamins, folate, and colon cancer (2001) (5)
- Maternal exposure to Wenchuan earthquake and prolonged risk of offspring birth outcomes: a natural experiment study (2020) (5)
- Correction: Defining the genetic susceptibility to cervical neoplasia—A genome-wide association study (2018) (4)
- Strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS): explanation and elaboration. (2011) (4)
- T-cell receptor excision circle levels and safety of paediatric immunization: A population-based self-controlled case series analysis (2018) (4)
- Development and field testing of a tool to elicit women's preferences among cervical cancer screening modalities. (2019) (4)
- Human genome epidemiology: The road map revisited (2010) (4)
- Problems and approaches in investigating the role of micronutrients in the aetiology of cancer in humans. (1999) (4)
- Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration (2011) (4)
- Screening for depression among the general adult population and in women during pregnancy or the first-year postpartum: two systematic reviews to inform a guideline of the Canadian Task Force on Preventive Health Care (2022) (4)
- MC1R variants and cutaneous melanoma risk according to histological type, body site, and Breslow thickness: a pooled analysis from the M-SKIP project (2020) (4)
- Impact of alternative management policies on health-related quality of life in women with low-grade abnormal cervical cytology referred for colposcopy. (2013) (3)
- Ultrastructural analysis of collagen fibril diameter distribution in cleft lip. (2018) (3)
- [Aspirin, non-steroidal anti-inflammatory agents and colonic carcinogenesis]. (1997) (3)
- Housing and health in West Belfast: a case study of Divis Flats and the Twinbrook Estate (1989) (3)
- Time trends, geographic variation and risk factors for gastroschisis in Canada: A population‐based cohort study 2006–2017 (2021) (3)
- Study protocol: the empirical investigation of methods to correct for measurement error in biobanks with dietary assessment (2011) (3)
- Seasonal variation in rates of emergency room visits and acute admissions following recommended infant vaccinations in Ontario, Canada: a self-controlled case series analysis. (2014) (3)
- Muscle fiber diameter assessment in cleft lip using image processing. (2018) (3)
- Metabolic Clinic Atlas: Organization of Care for Children with Inherited Metabolic Disease in Canada. (2015) (3)
- O-GYN-IWH-PhD-044 The Anishinaabek Cervical Cancer Screening Study (ACCSS): Barriers to and Strategies for Increasing Cervical Cancer Screening amongst First Nations Communities in Northwest Ontario (2016) (3)
- Analysis of tumour site concordance (2019) (3)
- Eliciting women’s cervical screening preferences: a mixed methods systematic review protocol (2016) (3)
- Associations between Serum Sex Hormone Concentrations and Telomere Length among U.S. Adults, 1999–2002 (2019) (3)
- Impact of post-colposcopy management on women's long-term worries: results from the UK population-based TOMBOLA trial (2015) (3)
- Epidemiology of Neural Tube Defects (2019) (3)
- Guidance relevant to the reporting of health equity in observational research: a scoping review protocol (2022) (2)
- Screening for prostate cancer: protocol for updating multiple systematic reviews to inform a Canadian Task Force on Preventive Health Care guideline update (2022) (2)
- Reporting of health equity considerations in equity-relevant observational studies: Protocol for a systematic assessment (2022) (2)
- Future risk of cancer in women who have children with birth defects. (2019) (2)
- External validation of machine learning models including newborn metabolomic markers for postnatal gestational age estimation in East and South-East Asian infants (2021) (2)
- A genetic variant in the placenta-derived MHC class I chain-related gene A increases the risk of preterm birth in a Chinese population (2017) (2)
- MC1R variants in relation to naevi in melanoma cases and controls: a pooled analysis from the M‐SKIP project (2020) (2)
- Title: Genetic discrimination and insurance in Canada: Where are we now? (2014) (2)
- Association between newborn screening analyte profiles and infant mortality (2019) (2)
- How Credible Are Meta-Analyses of Risk Factors Based on Observational Studies for Amyotrophic Lateral Sclerosis? A New Insight from an Umbrella Review (2016) (2)
- Cohort profile: Stop the Spread Ottawa (SSO)—a community-based prospective cohort study on antibody responses, antibody neutralisation efficiency and cellular immunity to SARS-CoV-2 infection and vaccination (2022) (2)
- The Role of Human Papillomavirus Testing in the Management of Women With Low-Grade Abnormalities: Multicentre Randomized Controlled Trial (2010) (2)
- Stillbirth in Canada: anachronistic definition and registration processes impede public health surveillance and clinical care (2021) (2)
- Screening for depression in children and adolescents: a protocol for a systematic review update (2021) (2)
- Genetic polymorphisms in folate metabolism, dietary folate intake and colorectal cancer: a population-based case-control study (2001) (2)
- A critical interpretive synthesis of evidence and values in recommendations to disinvest from population Screening (2016) (1)
- External validation of ELASTIC NET regression models including newborn metabolomic markers for postnatal gestational age estimation in East and South-East Asian infants. (2020) (1)
- Polymorphisms of adrenergic receptors and the risk of heart failure. (2003) (1)
- Associations between measures of pediatric human resources and the under-five mortality rate: a nationwide study in China in 2014 (2021) (1)
- Lethal Injection: Other Views (2007) (1)
- Extended reporting guidance for vaccine effectiveness studies for variants of concern for COVID-19 (2022) (1)
- Correction: Characterization of IGF-II Isoforms in Binge Eating Disorder and Its Group Psychological Treatment (2014) (1)
- Blood metals and vitamin D status in a pregnancy cohort: A bidirectional biomarker analysis. (2022) (1)
- The effect of performance-based financing interventions on out-of-pocket expenses intended to improve access to and utilization of maternal health services in sub-Saharan Africa: protocol for a systematic review and meta-analysis (2022) (1)
- Development of a risk assessment profile tool to determine appropriate use of SARS-CoV-2 rapid antigen detection tests for different activities and events in Ireland, since October 2021 (2022) (1)
- Issues associated with possible implementation of Non‐Invasive Prenatal Testing (NIPT) in first‐tier screening: A rapid scoping review (2022) (1)
- Seasonal respiratory virus circulation was diminished during the COVID‐19 pandemic (2022) (1)
- newborn screening about managing the incidental results of programmes : healthcare provider reasoning Clinical obligations and public health (2010) (0)
- Field Synopses of Genetic Variation in Colorectal Neoplasia (2012) (0)
- Author response: External validation of postnatal gestational age estimation using newborn metabolic profiles in Matlab, Bangladesh (2019) (0)
- Webtable 4, OR, HR and RR presented in each report for review question 1 (2009) (0)
- Webtable 7, Predictive values associated with FH definitions for colorectal cancer in cross-sectional analyses (2009) (0)
- Epidemiology of Colorectal Cancer (2006) (0)
- Appendix C - Studies Retained But Not Extracted (2009) (0)
- Webtable 5, Quality items for cancer studies for review question 1 (2009) (0)
- OP-IJEJ150184 1..20 (2015) (0)
- A REDCap database to support longitudinal follow-up of pediatric patients with inborn errors of metabolism (2014) (0)
- 127 Neonatal Abstinence Syndrome: Variation and Barriers in Care in Canada (2019) (0)
- Subgroup report: lymphohaematopoietic neoplasms. (2004) (0)
- Webtable 18, Quality items for diabetes studies for review question 1 (2009) (0)
- The impact of maternal and geographical factors on the uptake of non‐invasive prenatal testing: A retrospective cohort study (2022) (0)
- Webtable 17, Predictive values associated with FH definitions for diabetes in cross-sectional analyses (2009) (0)
- Examining the genotype–phenotype relationship for patients with very-long-chain acyl CoA dehydrogenase deficiency (2014) (0)
- Webtable 20, Predictive values associated with FH definitions for atopic disease in longitudinal analyses (2009) (0)
- Additional file 8: of Effectiveness of stop smoking interventions among adults: protocol for an overview of systematic reviews and an updated systematic review (2019) (0)
- Webtable 11, Predictive values associated with FH definitions for CHD in longitudinal analyses (2009) (0)
- Title Neuraminidase antibodies and H 5 N 1 : Geographic-dependent influenza epidemiology could determine cross-protection against emerging strains (2007) (0)
- Webtable 23, Predictive values associated with FH definitions for asthma in cross-sectional analyses (2009) (0)
- Webtable 13, Quality items for CVD and stroke studies for review question 1 (2009) (0)
- Building a pan-Canadian practice-based research network for inherited metabolic diseases: The first two years of the Canadian Inherited Metabolic Diseases Research Network (CIMDRN) (2014) (0)
- Appendix D - Excluded Studies (2009) (0)
- Webfigure 1, Cancer, risk of bias (2009) (0)
- Webfigure 3, Parkinson’s Disease, risk of bias (2009) (0)
- Webfigure 5, Cardiovascular disease and hypertension, risk of bias (2009) (0)
- Abstract A38: Role of MC1R variants in childhood and adolescent melanoma (2015) (0)
- Webtable 10, General data for cardiovascular and stroke studies (2009) (0)
- Gene variants, nutrition, and cancer. (2006) (0)
- P2-259 Cancer risk in children with birth defects: a longitudinal, population-based assessment among 2.7 million births (2011) (0)
- Additional file 5: of Effectiveness of stop smoking interventions among adults: protocol for an overview of systematic reviews and an updated systematic review (2019) (0)
- Search Strategies Detailed (2009) (0)
- Webtable 15, General data for diabetes studies (2009) (0)
- [Figure], Figure 2. Analytic framework for the research questions evaluated in this review (2009) (0)
- Webtable 19, General data for asthma studies (2009) (0)
- Appendix A - Search Strategies Detailed (2009) (0)
- SARS-CoV-2 Seroprevalence in Those Utilizing Public Transportation or Working in the Transportation Industry: A Rapid Review (2022) (0)
- University of Dundee Measuring the psychosocial burden in women with low-grade abnormal cervical cytology in the TOMBOLA trial (2017) (0)
- Appendix E - Partners, Technical Expert Panel, and Peer Reviewers (2009) (0)
- Low radon exposures & lung cancer risk: joint analysis of Czech, French & Beaverlodge uranium miners (2019) (0)
- Table 3, Family history-based risk stratification guidelines for breast, ovarian, colorectal, prostate cancers (2009) (0)
- Effects of three methods of breast milk expression on breastfeeding initiation, breast milk extraction and proportion of exclusive breastfeeding—an open label, randomized controlled trial (2020) (0)
- Metabolic clinic atlas: Organization of care for pediatric metabolic patients in Canada (2014) (0)
- Title : Muscle fiber diameter assessment in cleft lip using image processing (2017) (0)
- Vitamin D and breast cancer: interaction between dietary vitamin D and genetic variation in the vitamin D receptor may be implicated in the aetiology of breast cancer. (2001) (0)
- Webtable 8, Predictive values associated with FH definitions for prostate cancer in longitudinal analyses (2009) (0)
- Additional file 3: of Effectiveness of stop smoking interventions among adults: protocol for an overview of systematic reviews and an updated systematic review (2019) (0)
- Stopping screening. Facts, values, and decisions (2016) (0)
- Webtable 3, Predictive values associated with FH definitions for breast cancer cross-sectional analyses (2009) (0)
- TIME PERIODS OF PARENTAL EXPOSURE TO POLYCYCLIC AROMATIC HYDROCARBONS AND THE RISK OF CHILDHOOD BRAIN TUMORS (2004) (0)
- Authors' response to a refinement to ‘how many genes underlie the occurrence of common complex diseases in the population?’ by Ramal Moonesinghe (2006) (0)
- Webfigure 4, Diabetes, risk of bias (2009) (0)
- Webtable 22, Predictive values associated with FH definitions for asthma in longitudinal analyses (2009) (0)
- Table 12, Summary of SNPs and other variables included in test panels (2012) (0)
- Abstract 2244: The M-SKIP Project: an international pooled-analysis on melanocortin-1 receptor (MC1 R) variants and skin carcinogenesis (2011) (0)
- Webtable 6, Predictive values associated with FH definitions for colorectal cancer in longitudinal analyses (2009) (0)
- Patient- and family-oriented outcomes for inborn errors of metabolism: The perspective of patient advocacy and support groups (2014) (0)
- Evidence Tables and Figures (2009) (0)
- Contents Vol. 46, 2016 (2016) (0)
- Occupational risk factors for brain tumours in adults. Results from the international brain tumour case- control study (2001) (0)
- Systematic Meta-Analysis for Common Low Penetrance Genes in Colorectal Cancer (2012) (0)
- Webfigure 2, Mental health disorders, risk of bias (2009) (0)
- A genetic variant in the placenta-derived MHC class I chain-related gene A increases the risk of preterm birth in a Chinese population (2017) (0)
- MTHFR promoter methylation might mitigate the effect of smoking at the level of LINE‐1 in cleft lip tissues: A preliminary study (2021) (0)
- Integration of the evidence on gene-disease associations: Methods of HuGE reviews (2010) (0)
- Webtable 24, Quality items for asthma and atopy studies for review question 1 (2009) (0)
- Integration of the evidence on gene-disease associations: Methods of HuGE reviews (2010) (0)
- MC1R variants in childhood and adolescent melanoma: A pooled-analysis from a large worldwide multicenter cohort of patients (2019) (0)
- Additional file 2: of Effectiveness of stop smoking interventions among adults: protocol for an overview of systematic reviews and an updated systematic review (2019) (0)
- O-1 BARRIERS TO CERVICAL CANCER SCREENING AMONG WOMEN WHO HAVE BEEN ABUSED : AN EXPLORATORY STUDY (2011) (0)
- Appendix B - Forms and Guides (2009) (0)
- Reviewer Acknowledgment (2008) (0)
- Cohort Profile: The Ontario Health Study (OHS). (2022) (0)
- Interventions to address potentially inappropriate prescriptions and over-the-counter medication use among adults 65 years and older in primary care settings: protocol for a systematic review (2022) (0)
- Heterogeneous use of registry data for participant identification and primary outcome ascertainment is found in registry-based randomized controlled trials: A scoping review. (2023) (0)
- Webtable 28, Predictive values associated with FH definitions for major depressive disorder in cross-sectional analyses (2009) (0)
- Association between toxic metals, vitamin D and preterm birth in the Maternal-Infant research on environmental chemicals study. (2023) (0)
- Family Experiences with Care for Children with Inherited Metabolic Diseases in Canada: A Cross-Sectional Survey (2021) (0)
- Webtable 21, Predictive values associated with FH definitions for atopic disease cross-sectional analyses (2009) (0)
- The association between metals, vitamin D and preterm birth in the MIREC Cohort Study (2022) (0)
- STREGA Reporting Recommendations, Extended from STROBE Statement (2009) (0)
- Health services use by children identified as heterozygous hemoglobinopathy mutation carriers via newborn screening (2021) (0)
- Paper II: Thematic framework analysis of registry-based randomized controlled trials provided insights for designing trial ready registries. (2023) (0)
- Investigating Bidirectional Associations of Blood Metals and Vitamin D levels throughout Pregnancy: The MIREC Cohort Study (2021) (0)
- Improving social justice in observational studies: protocol for the development of a global and Indigenous STROBE-equity reporting guideline (2023) (0)
- Webtable 26, Predictive values associated with FH definitions for mood disorders in longitudinal analyses (2009) (0)
- Assessment of systematic effects of methodological characteristics on candidate genetic associations (2012) (0)
- Table 1, Pooled relative risk estimates (95% confidence intervals) for cancers of interest (2009) (0)
- Webtable 14, Predictive values associated with FH definitions for stroke in longitudinal analyses (2009) (0)
- Women’s experiences of having an abnormal smear result: qualitative analyses from TOMBOLA (2002) (0)
- Screening for Cervical Cancer: Protocol for Systematic Reviews to Inform Canadian Recommendations (2020) (0)
- [Figure], Figure 1. Family history-based primary care activities (2009) (0)
- Webtable 2, Predictive values associated with FH definitions for breast cancer in longitudinal analyses (2009) (0)
- Webtable 16, Predictive values associated with FH definitions for diabetes in longitudinal analyses (2009) (0)
- Rapid antigen-based and rapid molecular tests for the detection of SARS-CoV-2: a rapid review with network meta-analysis of diagnostic test accuracy studies (2023) (0)
- Health equity considerations in guideline development: a rapid scoping review (2023) (0)
- Guidelines for submitting human genome epidemiology (HuGE) reviews to Teratology (2001) (0)
- Webtable 25, General data for mental health studies (2009) (0)
- Gene-diet interactions in the aetiology of colorectal cancer: results from a population-based case-control study in north-east Scotland (2006) (0)
- Webtable 30, Studies excluded from Question 3 and Question 4 because of study design (2009) (0)
- Webtable 29, Quality items for mental illness studies for review question 1 (2009) (0)
- Patient- and family-oriented outcomes for inborn errors of metabolism: A scoping review (2014) (0)
- Reply to: Occupational risk factors for low grade and high grade glioma by B. Hocking (2005) (0)
- Table 2, Elements and key components of evaluation framework for family history as screening tool [reproduced from Yoon, Scheuner, and Khoury 2003] (2009) (0)
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Julian Little is affiliated with the following schools:
