Julie Chao
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- PhD Computer Science Stanford University
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Published Works
- Prostasin, a potential serum marker for ovarian cancer: identification through microarray technology. (2001) (295)
- Activation of the Phosphatidylinositol 3-Kinase/Protein Kinase Akt Pathway Mediates Nitric Oxide-Induced Endothelial Cell Migration and Angiogenesis (2003) (264)
- Regulation of the Epithelial Sodium Channel by Serine Proteases in Human Airways* (2002) (250)
- Local Delivery of Human Tissue Kallikrein Gene Accelerates Spontaneous Angiogenesis in Mouse Model of Hindlimb Ischemia (2001) (202)
- Prostasin is a novel human serine proteinase from seminal fluid. Purification, tissue distribution, and localization in prostate gland. (1994) (167)
- Transcription Factor Nuclear Factor κB Regulates the Inducible Expression of the Human B1 Receptor Gene in Inflammation* (1998) (156)
- Kallistatin is a new inhibitor of angiogenesis and tumor growth. (2002) (155)
- Direct gene delivery of human tissue kallikrein reduces blood pressure in spontaneously hypertensive rats. (1995) (146)
- Kallistatin: a novel human tissue kallikrein inhibitor. Purification, characterization, and reactive center sequence. (1992) (145)
- Human tissue kallikrein induces hypotension in transgenic mice. (1994) (137)
- Molecular Cloning, Tissue-specific Expression, and Cellular Localization of Human Prostasin mRNA (*) (1995) (136)
- Prolonged reduction of high blood pressure with human nitric oxide synthase gene delivery. (1997) (134)
- Degradation of apolipoprotein B-100 of human plasma low density lipoproteins by tissue and plasma kallikreins. (1984) (133)
- Kallikrein localization in rodent salivary glands and kidney with the immunoglobulin-enzyme bridge technique. (1979) (130)
- Adrenomedullin gene delivery attenuates myocardial infarction and apoptosis after ischemia and reperfusion. (2003) (130)
- Kallistatin, a novel human tissue kallikrein inhibitor: levels in body fluids, blood cells, and tissues in health and disease. (1996) (128)
- Regulation of prostasin by aldosterone in the kidney. (2002) (126)
- Tissue kallikrein-binding protein is a serpin. I. Purification, characterization, and distribution in normotensive and spontaneously hypertensive rats. (1990) (124)
- Adrenomedullin Protects Against Myocardial Apoptosis After Ischemia/Reperfusion Through Activation of Akt-GSK Signaling (2004) (121)
- Adrenomedullin Gene Delivery Attenuates Hypertension, Cardiac Remodeling, and Renal Injury in Deoxycorticosterone Acetate-Salt Hypertensive Rats (2000) (117)
- Identification of tissue kallikrein in brain and in the cell-free translation product encoded by brain mRNA. (1983) (116)
- Kallikrein protects against ischemic stroke by inhibiting apoptosis and inflammation and promoting angiogenesis and neurogenesis. (2006) (114)
- Prostasin Is a Glycosylphosphatidylinositol-anchored Active Serine Protease* (2001) (113)
- Kallikrein/kinin protects against gentamicin-induced nephrotoxicity by inhibition of inflammation and apoptosis. (2006) (112)
- Reduced cardiac hypertrophy and altered blood pressure control in transgenic rats with the human tissue kallikrein gene (2000) (111)
- Kallikrein/Kinin Protects against Myocardial Apoptosis after Ischemia/Reperfusion via Akt-Glycogen Synthase Kinase-3 and Akt-Bad·14-3-3 Signaling Pathways* (2005) (110)
- Kallikrein-modified mesenchymal stem cell implantation provides enhanced protection against acute ischemic kidney injury by inhibiting apoptosis and inflammation. (2008) (106)
- Kallikrein–kinin in stroke, cardiovascular and renal disease (2005) (106)
- Kallikrein Gene Transfer Protects Against Ischemic Stroke by Promoting Glial Cell Migration and Inhibiting Apoptosis (2004) (106)
- Human kallikrein gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in Dahl salt-sensitive rats. (1998) (106)
- Identification of a new tissue-kallikrein-binding protein. (1986) (104)
- Tissue kallikrein in rat brain and pituitary: regional distribution and estrogen induction in the anterior pituitary. (1987) (103)
- Human Endothelial Nitric Oxide Synthase Gene Delivery Promotes Angiogenesis in a Rat Model of Hindlimb Ischemia (2002) (102)
- The radioimmunoassay of human urinary kallikrein and comparisons with kallikrein activity measurements. (1980) (102)
- Inducible, brain region-specific expression of a dominant negative mutant of c-Jun in transgenic mice decreases sensitivity to cocaine (2003) (101)
- Kallikrein gene delivery attenuates hypertension and cardiac hypertrophy and enhances renal function in Goldblatt hypertensive rats. (1998) (96)
- Kallikrein gene delivery attenuates myocardial infarction and apoptosis after myocardial ischemia and reperfusion. (2000) (94)
- Kallikrein Gene Delivery Improves Cardiac Reserve and Attenuates Remodeling After Myocardial Infarction (2002) (94)
- Postischemic Brain Injury Is Exacerbated in Mice Lacking the Kinin B2 Receptor (2006) (93)
- Hypotension in transgenic mice overexpressing human bradykinin B2 receptor. (1997) (92)
- Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammation. (2005) (92)
- Tissue kallikrein in cardiovascular, cerebrovascular and renal diseases and skin wound healing (2010) (91)
- Structure and chromosomal localization of the gene (BDKRB2) encoding human bradykinin B2 receptor. (1994) (91)
- Human atrial natriuretic peptide gene delivery reduces blood pressure in hypertensive rats. (1995) (90)
- Kallistatin is a potent new vasodilator. (1997) (88)
- Expression and cellular localization of the kallikrein-kinin system in human ocular tissues. (1996) (88)
- Salutary Effect of Kallistatin in Salt-Induced Renal Injury, Inflammation, and Fibrosis via Antioxidative Stress (2008) (87)
- Human endothelial nitric oxide synthase gene delivery protects against cardiac remodeling and reduces oxidative stress after myocardial infarction. (2005) (87)
- Prevention of Diabetes-Induced Microangiopathy by Human Tissue Kallikrein Gene Transfer (2002) (85)
- Rescue of Impaired Angiogenesis in Spontaneously Hypertensive Rats by Intramuscular Human Tissue Kallikrein Gene Transfer (2001) (84)
- Human tissue kallikrein gene delivery attenuates hypertension, renal injury, and cardiac remodeling in chronic renal failure. (2000) (83)
- Localization and Expression of Tissue Kallikrein and Kallistatin in Human Blood Vessels (1999) (80)
- Adenovirus-Mediated Human Tissue Kallikrein Gene Delivery Induces Angiogenesis in Normoperfused Skeletal Muscle (2000) (79)
- Overexpression of Kinin B1 Receptors Induces Hypertensive Response to Des-Arg9-bradykinin and Susceptibility to Inflammation* (2003) (78)
- Proteomic Analysis Reveals Alterations in the Renal Kallikrein Pathway during Hypoxia-Induced Hypertension* (2002) (77)
- Kallistatin: a novel human serine proteinase inhibitor. Molecular cloning, tissue distribution, and expression in Escherichia coli. (1993) (77)
- Muscle delivery of human kallikrein gene reduces blood pressure in hypertensive rats. (1995) (76)
- Regulation of bradykinin B2‐receptor expression by oestrogen (1997) (75)
- The tissue kallikrein-kinin system protects against cardiovascular and renal diseases and ischemic stroke independently of blood pressure reduction (2006) (75)
- Novel role of kallistatin in protection against myocardial ischemia-reperfusion injury by preventing apoptosis and inflammation. (2006) (74)
- Tissue distribution and kininogen gene expression after acute-phase inflammation. (1988) (74)
- Kallikrein gene delivery improves serum glucose and lipid profiles and cardiac function in streptozotocin-induced diabetic rats. (2005) (73)
- Human adrenomedullin gene delivery protects against cardiac hypertrophy, fibrosis, and renal damage in hypertensive dahl salt-sensitive rats. (2000) (72)
- Kallistatin protects against sepsis-related acute lung injury via inhibiting inflammation and apoptosis (2015) (72)
- Kallistatin reduces vascular senescence and aging by regulating microRNA‐34a‐SIRT1 pathway (2017) (72)
- Kallistatin attenuates endothelial apoptosis through inhibition of oxidative stress and activation of Akt-eNOS signaling. (2010) (71)
- Kruppel-like Factor 4 Is a Novel Mediator of Kallistatin in Inhibiting Endothelial Inflammation via Increased Endothelial Nitric-oxide Synthase Expression* (2009) (69)
- Adrenomedullin gene delivery attenuates renal damage and cardiac hypertrophy in Goldblatt hypertensive rats. (2001) (69)
- Atrial natriuretic peptide gene delivery attenuates hypertension, cardiac hypertrophy, and renal injury in salt-sensitive rats. (1998) (68)
- Kallistatin Inhibits Vascular Inflammation by Antagonizing Tumor Necrosis Factor-&agr;-Induced Nuclear Factor &kgr;B Activation (2010) (68)
- Adrenomedullin gene delivery reduces blood pressure in spontaneously hypertensive rats. (1997) (68)
- Tissue kallikrein activation of the epithelial Na channel. (2012) (67)
- Adrenomedullin gene delivery protects against cerebral ischemic injury by promoting astrocyte migration and survival. (2004) (67)
- A synthetic tissue kallikrein inhibitor suppresses cancer cell invasiveness. (2001) (67)
- Dysregulation of kallikrein-related peptidases in renal cell carcinoma: potential targets of miRNAs (2010) (66)
- Kallistatin inhibits TGF-β-induced endothelial-mesenchymal transition by differential regulation of microRNA-21 and eNOS expression. (2015) (66)
- Kinin Infusion Prevents Renal Inflammation, Apoptosis, and Fibrosis via Inhibition of Oxidative Stress and Mitogen-Activated Protein Kinase Activity (2007) (66)
- Abnormal regulation of renal kallikrein in experimental diabetes. Effects of insulin on prokallikrein synthesis and activation. (1987) (66)
- Kallikrein Multigene Families and the Regulation of Their Expression (1990) (66)
- Tissue kallikrein attenuates salt-induced renal fibrosis by inhibition of oxidative stress. (2004) (65)
- A common nomenclature for members of the tissue (glandular) kallikrein gene families. (1992) (65)
- Molecular cloning and expression of rat bradykinin B1 receptor. (1998) (65)
- Biochemistry, regulation and potential function of kallistatin. (1995) (64)
- Isozymes of rat urinary kallikrein. (1979) (63)
- Adrenomedullin improves cardiac function and prevents renal damage in streptozotocin-induced diabetic rats. (2002) (62)
- Tissue Kallikrein Elicits Cardioprotection by Direct Kinin B2 Receptor Activation Independent of Kinin Formation (2008) (62)
- A novel signaling pathway of tissue kallikrein in promoting keratinocyte migration: activation of proteinase-activated receptor 1 and epidermal growth factor receptor. (2010) (60)
- Cellular localization of tissue kallikrein and kallistatin mRNAs in human kidney. (1995) (59)
- Effects of diabetes and insulin on expression of kallikrein and renin genes in the kidney. (1992) (59)
- A direct radioimmunoassay of rat urinary kallikrein and comparison with other measures of urinary kallikrein activity. (1979) (59)
- Novel Roles of Kallistatin, a Specific Tissue Kallikrein Inhibitor, in Vascular Remodeling (2001) (59)
- Identification of a Major Heparin-binding Site in Kallistatin* (2001) (58)
- Structural elements of kallistatin required for inhibition of angiogenesis. (2003) (58)
- Reversal of renal fibrosis, inflammation, and glomerular hypertrophy by kallikrein gene delivery. (2006) (58)
- Structure and chromosomal localization of the human prostasin (PRSS8) gene. (1996) (58)
- Role of kallistatin in prevention of cardiac remodeling after chronic myocardial infarction (2008) (57)
- Kallikrein gene delivery inhibits vascular smooth muscle cell growth and neointima formation in the rat artery after balloon angioplasty. (1999) (57)
- Gene Therapy With Human Tissue Kallikrein Reduces Hypertension and Hyperinsulinemia in Fructose-Induced Hypertensive Rats (2003) (57)
- Tissue kallikrein promotes neovascularization and improves cardiac function by the Akt-glycogen synthase kinase-3beta pathway. (2008) (55)
- Intermedin is a new angiogenic growth factor. (2009) (55)
- The effects of aldosterone and spironolactone on renal kallikrein in the rat. (1976) (54)
- Immunological identification of rat tissue kallikrein cDNA and characterization of the kallikrein gene family. (1986) (53)
- Postischemic infusion of adrenomedullin protects against ischemic stroke by inhibiting apoptosis and promoting angiogenesis (2006) (53)
- Restriction fragment length polymorphisms mapped in spontaneously hypertensive rats using kallikrein probes. (1989) (52)
- Intramuscular Delivery of Rat Kallikrein-binding Protein Gene Reverses Hypotension in Transgenic Mice Expressing Human Tissue Kallikrein (*) (1995) (51)
- Arachidonic Acid and Its Metabolites in Cerebral Ischemia a (1989) (51)
- Adenovirus-mediated delivery of human kallistatin gene reduces blood pressure of spontaneously hypertensive rats. (1997) (51)
- Tissue kallikrein protects against pressure overload-induced cardiac hypertrophy through kinin B2 receptor and glycogen synthase kinase-3beta activation. (2007) (51)
- Kallikrein activation of a high molecular weight atrial peptide. (1984) (50)
- Tissue kallikrein infusion prevents cardiomyocyte apoptosis, inflammation and ventricular remodeling after myocardial infarction (2007) (50)
- Down‐regulated expression of prostasin in high‐grade or hormone‐refractory human prostate cancers (2003) (50)
- Bradykinin B(1) receptor mediates inhibition of neointima formation in rat artery after balloon angioplasty. (2000) (50)
- Role of tissue kallikrein in prevention and recovery of gentamicin-induced renal injury. (2008) (50)
- Adenovirus-mediated kallikrein gene delivery reverses salt-induced renal injury in Dahl salt-sensitive rats. (1998) (50)
- Association of the tissue kallikrein gene promoter with ESRD and hypertension. (2002) (49)
- Amiloride inhibits mammalian renal kallikrein and a kallikrein-like enzyme from toad bladder and skin. (1980) (49)
- Human adrenomedullin gene delivery protects against cardiovascular remodeling and renal injury (2001) (49)
- Protective Role of Kallistatin in Vascular and Organ Injury (2016) (48)
- Differential regulation of kininogen gene expression by estrogen and progesterone in vivo. (1992) (48)
- Genomic DNA sequence, expression, and chromosomal localization of the human B1 bradykinin receptor gene BDKRB1. (1996) (47)
- Adenovirus-mediated kallistatin gene transfer ameliorates disease progression in a rat model of osteoarthritis induced by anterior cruciate ligament transection. (2008) (47)
- Recombinant adeno-associated virus-mediated kallikrein gene therapy reduces hypertension and attenuates its cardiovascular injuries (2004) (46)
- Kallikrein gene delivery attenuates cardiac remodeling and promotes neovascularization in spontaneously hypertensive rats. (2003) (46)
- Early activation of bradykinin B2 receptor aggravates reactive oxygen species generation and renal damage in ischemia/reperfusion injury. (2006) (46)
- Molecular cloning and analysis of the rat kallikrein-binding protein gene. (1991) (46)
- Immunocytochemical localization of tissue kallikrein in brain ventricular epithelium and hypothalamic cell bodies. (1985) (45)
- Tissue kallikrein reverses insulin resistance and attenuates nephropathy in diabetic rats by activation of phosphatidylinositol 3-kinase/protein kinase B and adenosine 5'-monophosphate-activated protein kinase signaling pathways. (2007) (45)
- Cloning, sequence analysis and expression of the gene encoding the mouse bradykinin B2 receptor. (1994) (45)
- Kallikrein-binding protein levels are reduced in the retinas of streptozotocin-induced diabetic rats. (1997) (45)
- Kallistatin induces breast cancer cell apoptosis and autophagy by modulating Wnt signaling and microRNA synthesis. (2016) (45)
- Human kallikrein gene delivery protects against gentamycin-induced nephrotoxicity in rats. (1998) (45)
- Identification, purification, and localization of tissue kallikrein in rat heart. (1990) (44)
- Tissue kallikrein synthesis and its modification by testosterone or low dietary sodium. (1984) (44)
- Atrial natriuretic peptide gene delivery reduces stroke-induced mortality rate in Dahl salt-sensitive rats. (1999) (44)
- Systemic and portal vein delivery of human kallikrein gene reduces blood pressure in hypertensive rats. (1996) (44)
- Human kallistatin administration reduces organ injury and improves survival in a mouse model of polymicrobial sepsis (2014) (44)
- Nitric oxide mediates cardiac protection of tissue kallikrein by reducing inflammation and ventricular remodeling after myocardial ischemia/reperfusion. (2008) (42)
- Kallistatin antagonizes Wnt/β-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6 (2013) (42)
- Pivotal role of JNK-dependent FOXO1 activation in downregulation of kallistatin expression by oxidative stress. (2010) (42)
- Kallistatin in human ocular tissues: reduced levels in vitreous fluids from patients with diabetic retinopathy. (1996) (42)
- Differential role of kinin B1 and B2 receptors in ischemia-induced apoptosis and ventricular remodeling (2007) (42)
- Roles of the P1, P2, and P3 Residues in Determining Inhibitory Specificity of Kallistatin toward Human Tissue Kallikrein* (2000) (42)
- Differential effects of testosterone, thyroxine, and cortisol on rat submandibular gland versus renal kallikrein. (1983) (42)
- Intermedin ameliorates vascular and renal injury by inhibition of oxidative stress. (2008) (41)
- Adenovirus-mediated kallikrein gene delivery reduces aortic thickening and stroke-induced death rate in Dahl salt-sensitive rats. (1999) (41)
- Gene therapy in hypertension: adenovirus-mediated kallikrein gene delivery in hypertensive rats. (1997) (41)
- Enhanced renal function in bradykinin B(2) receptor transgenic mice. (2000) (41)
- In vivo catabolism of human kallikrein-binding protein and its complex with tissue kallikrein. (1992) (41)
- A major difference of kallikrein-binding protein in spontaneously hypertensive versus normotensive rats. (1988) (40)
- Molecular cloning, purification and in situ localization of human colon kallikrein. (1995) (40)
- The bradykinin B1 receptor and the central regulation of blood pressure in spontaneously hypertensive rats (1999) (40)
- Renal kallikrein mRNA localization by in situ hybridization. (1989) (40)
- Depletion of endogenous kallistatin exacerbates renal and cardiovascular oxidative stress, inflammation, and organ remodeling. (2012) (39)
- Adenovirus-mediated kallikrein gene delivery attenuates hypertension and protects against renal injury in deoxycorticosterone-salt rats. (1999) (38)
- Kallikrein-kinin system and blood pressure sensitivity to salt. (1997) (38)
- Kallistatin Modulates Immune Cells and Confers Anti-Inflammatory Response To Protect Mice from Group A Streptococcal Infection (2013) (37)
- Kallikrein-induced uterine contraction independent of kinin formation. (1981) (37)
- Protective Role of Endogenous Kallistatin in Vascular Injury and Senescence by Inhibiting Oxidative Stress and Inflammation (2018) (37)
- Molecular cloning and characterization of two rat renal kallikrein genes. (1988) (37)
- Studies on rat renal cortical cell kallikrein. II. Identification of kallikrein as an ecto-enzyme. (1979) (37)
- Beneficial effects of kallikrein-binding protein in transgenic mice during endotoxic shock. (1997) (37)
- Prostasin attenuates inducible nitric oxide synthase expression in lipopolysaccharide-induced urinary bladder inflammation. (2006) (37)
- Experimental therapy with tissue kallikrein against cerebral ischemia. (2006) (36)
- Plasma kallistatin levels in patients with severe community-acquired pneumonia (2013) (36)
- Tissue kallikrein promotes prostate cancer cell migration and invasion via a protease-activated receptor-1-dependent signaling pathway (2010) (36)
- Substrate specificities of tissue kallikrein and T-kininogenase: their possible role in kininogen processing. (1992) (36)
- Sex dimorphism and hormonal regulation of rat tissue kallikrein mRNA. (1986) (35)
- DNA polymorphisms in the 5′-flanking region of the human tissue kallikrein gene (1997) (34)
- Potassium supplement upregulates the expression of renal kallikrein and bradykinin B2 receptor in SHR. (1999) (34)
- Reactive-site specificity of human kallistatin toward tissue kallikrein probed by site-directed mutagenesis. (2000) (34)
- Inhibition of experimental lung metastasis by systemic lentiviral delivery of kallistatin (2010) (34)
- Activation of serpins and their cognate proteases in muscle after crush injury (1994) (34)
- Inhibition of rat tissue kallikrein gene family members by rat kallikrein‐binding protein and α1‐proteinase inhibitor (1992) (33)
- Purification and characterization of a kallikrein-like T-kininogenase. (1990) (33)
- Tissue kallikrein and kinin infusion rescues failing myocardium after myocardial infarction. (2007) (33)
- Molecular cloning and primary structure of rat alpha 1-antitrypsin. (1990) (33)
- Kallistatin treatment attenuates lethality and organ injury in mouse models of established sepsis (2015) (32)
- Adenovirus-mediated human prostasin gene delivery is linked to increased aldosterone production and hypertension in rats. (2003) (32)
- Adenovirus-mediated human tissue kallikrein gene delivery inhibits neointima formation induced by interruption of blood flow in mice. (2000) (32)
- Reversal of Angiogenic Growth Factor Upregulation by Revascularization of Lower Limb Ischemia (2002) (31)
- Functional analysis of human tissue kallikrein in transgenic mouse models. (1996) (31)
- Tissue Kallikrein-binding Protein Reduces Blood Pressure in Transgenic Mice* (1996) (31)
- Role of the bradykinin B2 receptor in the maturation of blood pressure phenotype: lesson from transgenic and knockout mice. (1999) (30)
- Human plasma inactive renin: purification and activation by proteases. (1982) (30)
- Identification and characterization of a tissue kallikrein in rat skeletal muscles. (1987) (30)
- Novel Role of Kallistatin in Vascular Repair by Promoting Mobility, Viability, and Function of Endothelial Progenitor Cells (2014) (30)
- High level of circulating human tissue kallikrein induces hypotension in a transgenic mouse model. (1996) (30)
- Kallistatin stimulates vascular smooth muscle cell proliferation and migration in vitro and neointima formation in balloon-injured rat artery. (2000) (30)
- Kallikrein gene transfer reduces renal fibrosis, hypertrophy, and proliferation in DOCA-salt hypertensive rats. (2005) (29)
- Differential interactions of human kallikrein-binding protein and alpha 1-antitrypsin with human tissue kallikrein. (1990) (29)
- Molecular cloning, sequence analysis, and chromosomal localization of the human protease inhibitor 4 (kallistatin) gene (PI4). (1994) (29)
- Inhibitory effects of sodium and other monovalent cations on purified versus membrane-bound kallikrein. (1983) (29)
- Cellular localization of low-molecular-weight kininogen and bradykinin B2 receptor mRNAs in human kidney. (1996) (29)
- Human urinary kallikrein. Complete amino acid sequence and sites of glycosylation. (2009) (28)
- Localization and secretion of tissue kallikrein in peptidoglycan-induced enterocolitis in Lewis rats. (1998) (28)
- Excretion of human urinary kallikrein quantity measured by a direct radioimmunoassay of human urinary kallikrein in patients with essential hypertension and secondary hypertensive diseases. (1981) (27)
- Cellular localization of kallistatin and tissue kallikrein in human pancreas and salivary glands (1998) (27)
- High-salt diet upregulates kininogen and downregulates tissue kallikrein expression in Dahl-SS and SHR rats. (1996) (27)
- Ribonucleotides Covalently Linked to Deoxyribonucleic Acid in T4 Bacteriophage (1972) (27)
- Isolation of tissue kallikrein in rat spleen by monoclonal antibody-affinity chromatography. (1984) (26)
- Experimental kallikrein gene therapy in hypertension, cardiovascular and renal diseases. (1997) (26)
- Tissue kallikrein promotes cardiac neovascularization by enhancing endothelial progenitor cell functional capacity. (2012) (26)
- Tissue kallikrein and kinin infusion promotes neovascularization in limb ischemia (2008) (25)
- Immunoreactive tissue kallikrein in human serum. (1984) (24)
- Relationship between the regulatory region polymorphism of human tissue kallikrein gene and essential hypertension (2005) (24)
- Identification and expression of kallikrein gene family in rat submandibular and prostate glands using monoclonal antibodies as specific probes. (1987) (24)
- Plasma kallistatin is associated with adiposity and cardiometabolic risk in apparently healthy African American adolescents. (2013) (23)
- A Positively Charged Loop on the Surface of Kallistatin Functions to Enhance Tissue Kallikrein Inhibition by Acting as a Secondary Binding Site for Kallikrein* (2000) (23)
- Specificity of human tissue kallikrein towards substrates containing Phe-Phe pair of amino acids. (1999) (22)
- α1-Antichymotrypsin and Kallistatin Hydrolysis by Human Cathepsin D (2000) (22)
- Molecular cloning and sequence analysis of rat bradykinin B2 receptor gene. (1994) (22)
- Blockade of endogenous tissue kallikrein aggravates renal injury by enhancing oxidative stress and inhibiting matrix degradation. (2010) (22)
- Circulating Tissue Kallikrein Levels Correlate With Severity of Carotid Atherosclerosis (2004) (22)
- Differential regulation of kallikrein, kininogen, and kallikrein-binding protein in arterial hypertensive rats. (1996) (21)
- Molecular cloning and characterization of a novel kallikrein transcript in colon and its distribution in human tissues. (1994) (21)
- Tissue Kallikrein-Modified Human Endothelial Progenitor Cell Implantation Improves Cardiac Function via Enhanced Activation of Akt and Increased Angiogenesis (2013) (21)
- Expression of kallikrein-binding protein and alpha 1-antitrypsin genes in response to sex hormones, growth, inflammation and hypertension. (1992) (21)
- Age and hormonal dependence of tonin levels in rat submandibular gland as determined by a new direct radioimmunoassay. (1986) (21)
- Upregulation of kallistatin expression in rheumatoid joints. (2007) (20)
- Adrenomedullin gene delivery inhibits neointima formation in rat artery after balloon angioplasty (2003) (20)
- Characterization of genes encoding rat tonin and a kallikrein-like serine protease. (1989) (20)
- Bradykinin B1 Receptor Mediates Inhibition of Neointima Formation in Rat Artery After Balloon Angioplasty (2000) (20)
- Structural organization of apolipoprotein B-100 of human plasma low density lipoproteins. Comparison to B-48 of chylomicrons and very low density lipoproteins. (1986) (20)
- Kallistatin attenuates endothelial senescence by modulating Let‐7g‐mediated miR‐34a‐SIRT1‐eNOS pathway (2018) (20)
- Human tissue kallikrein attenuates hypertension and secretes into circulation and urine after intramuscular gene delivery in hypertensive rats. (1999) (19)
- Participation of kinins in the captopril‐induced inhibition of intimal hyperplasia caused by interruption of carotid blood flow in the mouse (2000) (19)
- Prostasin: a possible candidate gene for human hypertension. (2008) (19)
- Kallistatin Ameliorates Influenza Virus Pathogenesis by Inhibition of Kallikrein-Related Peptidase 1-Mediated Cleavage of Viral Hemagglutinin (2015) (18)
- Electron microscopic immunostaining of kallikrein in rat submandibular glands. (1983) (18)
- Glandular kallikrein gene expression is selectively down-regulated by glucocorticoids in pancreatic AR42J cells. (1991) (18)
- Characterization of monoclonal and polyclonal antibodies to human tissue kallikrein. (1985) (18)
- Specific identification of tissue kallikrein in exocrine tissues and in cell-free translation products with monoclonal antibodies. (1985) (18)
- Atrial natriuretic peptide gene delivery attenuates gentamycin-induced nephrotoxicity in rats. (1999) (18)
- Antisense inhibition of the brain kallikrein-kinin system. (1996) (18)
- Adenovirus-mediated kallikrein gene transfer inhibits neointima formation via increased production of nitric oxide in rat artery. (1999) (18)
- The Role of Adrenomedullin in Cardiovascular and Renal Function. (2002) (18)
- Expression of human tissue kallikrein in rat salivary glands and its secretion into circulation following adenovirus-mediated gene transfer. (1997) (18)
- Central delivery of human tissue kallikrein gene reduces blood pressure in hypertensive rats. (1998) (17)
- Tissue kallikrein-modified mesenchymal stem cells provide enhanced protection against ischemic cardiac injury after myocardial infarction. (2013) (17)
- Role of Kallistatin Treatment in Aging and Cancer by Modulating miR-34a and miR-21 Expression (2017) (17)
- Expression and cellular localization of tissue kallikrein-kinin system in human adrenal gland. (1996) (17)
- Molecular cloning and sequence analysis of the monkey and human tissue kallikrein genes. (1993) (16)
- Tissue Kallikrein and Tonin Levels in Submandibular Glands of STZ-Induced Diabetic Rats and the Effects of Insulin (1993) (16)
- Kallistatin suppresses cancer development by multi-factorial actions. (2017) (16)
- Molecular cloning and sequence analysis of the mouse kallikrein-binding protein gene. (1991) (16)
- Sex dimorphism and inflammatory regulation of T-kininogen and T-kininogenase. (1989) (15)
- Reduced Plasma Kallistatin Is Associated With the Severity of Coronary Artery Disease, and Kallistatin Treatment Attenuates Atherosclerotic Plaque Formation in Mice (2018) (15)
- Kallistatin: double-edged role in angiogenesis, apoptosis and oxidative stress (2017) (15)
- Purification and characterization of recombinant tissue kallikrein from Escherichia coli and yeast. (1991) (15)
- The bradykinin B 1 receptor and the central regulation of blood pressure in spontaneously hypertensive rats (1999) (15)
- Biochemical characterization and substrate specificity of rat prostate kallikrein (S3): comparison with tissue kallikrein, tonin and T-kininogenase. (1992) (15)
- Activity and structural changes of purified kallikrein with detergent treatment. (1978) (15)
- Tissue kallikrein inhibitors in mammals. (1996) (15)
- Plasma kallistatin in critically ill patients with severe sepsis and septic shock (2017) (15)
- Kallikrein gene therapy: a new strategy for hypertensive diseases. (1997) (14)
- Identification of latent tissue kallikrein, prolactin and growth hormone secretion in GH3 pituitary cells using modified radioimmunoassays (1988) (14)
- A method for determination of human urinary inactive kallikrein (prekallikrein). (1982) (14)
- Distribution of tissue kallikreins in lower vertebrates: potential physiological roles for fish kallikreins. (1997) (14)
- Adenovirus-Mediated eNOS Expression Augments Liver Injury after Ischemia/Reperfusion in Mice (2014) (14)
- Regulation of rat renal kallikrein expression by estrogen and progesterone. (1991) (14)
- Immunohistochemical Localization of Kininogen in Rat Spinal Cord and Brain (1999) (13)
- High level expression of human tissue kallikrein in the circulation induces hypotension in transgenic mice. (1996) (13)
- Regulation of Kininogen Gene Expression and Localization in the Lung after Monocrotaline-Induced Pulmonary Hypertension in Rats (1993) (13)
- Kallikrein gene therapy in hypertension , cardiovascular and renal diseases (2001) (13)
- Co-localization of a kallikrein-like serine protease (arginine esterase A) and atrial natriuretic peptide in rat atrium. (1989) (13)
- Identification of a kallikrein-like latent serine protease in human erythrocyte membranes. (1984) (12)
- Urinary Prostasin: A Possible Biomarker for Renal Pressure Natriuresis in Black Adolescents (2009) (12)
- Bacteriophage T4 head morphogenesis: host DNA enzymes affect frequency of petite forms. (1974) (12)
- Opposing Effects of Oxygen Regulation on Kallistatin Expression: Kallistatin as a Novel Mediator of Oxygen-Induced HIF-1-eNOS-NO Pathway (2017) (12)
- Kallikrein gene therapy in newborn and adult hypertensive rats. (1997) (12)
- Molecular cloning and characterization of rKlk10, a cDNA encoding T-kininogenase from rat submandibular gland and kidney. (1992) (12)
- Effect of cyclosporin A on the expression of tissue kallikrein, kininogen, and bradykinin receptor in rat. (1997) (11)
- Differential Developmental Expression of the Rat Kininogen Genes (1992) (10)
- An improved method for the measurement of rat tissue kallikrein using a monoclonal antibody which recognizes only active enzyme. (1986) (10)
- Human tissue kallikrein in the treatment of acute ischemic stroke (2019) (10)
- Purification and characterization of tissue kallikrein-like proteinases from the black sea bass (Centropristis striata) and the southern frog (Rana berlandieri). (1995) (10)
- The purification of human urinary kallikrein with ion-exchange radial flow membrane chromatography. (1996) (10)
- Subcellular distribution of tissue kallikrein and Na,K-ATPase α-subunit in rat parotid striated duct cells (1994) (10)
- Human kallistatin, a new tissue kallikrein-binding protein: purification and characterization. (1989) (9)
- Purification, characterization and activation of fish muscle prokallikrein. (1997) (9)
- Measurement of the rat urinary plasminogen activator (esterase A) by direct radioimmunoassay in urine and tissue. (1984) (9)
- Kallistatin in blood pressure regulation transgenic and somatic gene delivery studies. (1997) (9)
- Molecular cloning and expression of rat kallistatin gene. (1997) (8)
- Immunocytochemical localization of a kallikrein‐like serin protease (Esterase A) in rat salivary glands (1988) (8)
- Expression and characterization of rat kallikrein-binding protein in Escherichia coli. (1993) (8)
- Protective role of kallistatin in renal fibrosis via modulation of Wnt/β-catenin signaling. (2021) (8)
- Identification of tonin in brain and exocrine tissues and in the cell-free translation products encoded by the mRNA of these tissues. (1987) (8)
- Tissue kallikrein-kinin therapy in hypertension and organ damage. (2014) (8)
- Sexual dimorphism of cardiovascular responses to early blockade of bradykinin receptors. (1996) (8)
- Specificity determinants of rat tissue kallikrein probed by site-directed mutagenesis. (1992) (7)
- Regulatory elements in the promoter region of the renal kallikrein gene in normotensive vs hypertensive rats. (1995) (7)
- Purification and characterization of salivary kallikrein from an insectivore (Scalopus aquaticus): substrate specificities, immunoreactivity, and kinetic analyses. (1996) (7)
- Histopathology of lymphatic tissues in transgenic mice expressing human tissue kallikrein gene. (1994) (7)
- Enhanced specificity in immunoscreening of expression cDNA clones using radiolabeled antigen overlay. (1989) (7)
- Cellular localization of bradykinin B1 receptor mRNA in the human kidney. (1996) (7)
- Kallikrein content of rat pancreatic acinar cells or islets by direct radioimmunoassay. (1980) (7)
- Tissue kallikrein is related to the severity of coronary artery disease. (2013) (6)
- Localization of kallikrein gene family proteases in rat tissues. (1992) (6)
- New experimental evidence for a role of tissue kallikrein in hypertension. (1997) (6)
- Studies of the kallikrein-kinin system and prostaglandins in epithelial ion transport. (1985) (6)
- Expression and localization of human kallistatin in rat submandibular gland after intracapsular gene injection. (1997) (6)
- The inhibition of f2 RNA directed E. coli protein synthesis by poly rI-rC in vitro. (1971) (6)
- Identification and characterization of two promoters of rat kallikrein-binding protein gene. (1996) (6)
- Kallikrein-kinin in stem cell therapy. (2014) (6)
- Plasma Kallistatin is Associated with Leukocyte Telomere Length in Young African Americans (2016) (5)
- Immunological analysis of rat pancreatic prokallikrein activation. (1985) (5)
- Urinary Levels of Kallikrein and Kallistatin in Pregnancy-Induced Hypertension (1995) (5)
- 415 – IDENTIFICATION OF KALLIKREIN IN TOAD URINARY BLADDER AND SKIN AND ITS INHIBITION BY AMILORIDE (1978) (5)
- Evolution of the kallikrein gene family. (1992) (4)
- Rat urinary kallikrein localization in kidney: Effects of fixation (1987) (4)
- Tissue-specific expression and promoter analyses of the human tissue kallikrein gene in transgenic mice. (1997) (4)
- A simple procedure for high efficiency counting of labeled protein bands in polyacrylamide slab gels (1981) (4)
- Active kallikrein, preprokallikrein, and kallikrein-inhibitor complex. (1986) (4)
- Kallikrein‐binding protein is induced by growth hormone in the dwarf rat (1999) (4)
- Comparison of the distribution of tissue kallikrein and esterase A, a kallikrein-like enzyme, in rat kidney using specific monoclonal antibodies. (1988) (4)
- [12] Rat urinary kallikrein (1988) (3)
- Tissue kallikreins in evolutionarily diverse vertebrates. (1996) (3)
- Austin Biomarkers & Diagnosis Kallistatin: A Novel Biomarker for Hypertension, Organ Injury and Cancer (2015) (3)
- Circulating Autoantibodies to Mammalian Tissue Kallikreins 1 (1988) (3)
- A monoclonal antibody to rat tissue kallikrein: use in biochemical and immunohistochemical studies. (1986) (3)
- Tissue Kallikrein Reverses Insulin Resistance and Attenuates Nephropathy in Diabetic Rats by Activation of PI3 kinase/Akt and AMPK Signaling Pathways (2013) (3)
- Response to Deficiency of Bradykinin Receptor B2 Is not Detrimental in Experimental Stroke (2008) (3)
- Characterization of rat kallikrein-like multigene family and its expression in the submandibular gland. (1986) (3)
- Structural analysis of a rat renal kallikrein gene. (1989) (3)
- Active-site labeling of rat and human urinary kallikrein by chloro(N alpha-p-tosyllysyl)methane. (1981) (2)
- Human Kallikrein-related Peptidase 2 (2013) (2)
- Comparative studies on P2 specificity of wild-type rat tissue kallikrein, Y99H:W215G mutant and tonin. (1992) (2)
- Sex dimorphism and estrogen regulation of kininogens in rat serum, adrenal gland and kidney. (1989) (2)
- Encapsulated transgene cells attenuate hypertension, cardiac hypertrophy and enhance renal function in Goldblatt hypertensive rats (2004) (2)
- Rat urinary kallikrein. (1988) (2)
- 414 – IDENTIFICATION OF KALLIKREIN ON EXTERNAL CELL SURFACES (1978) (2)
- Human Kallikrein 1,Tissue Kallikrein (2013) (2)
- Kallikrein Gene Transfer in Hypertension, Cardiovascular and Renal Disease, and Stroke (2005) (1)
- Kallikrein localization in rat brain by immunohistochemistry. (1986) (1)
- function by the Akt-glycogen synthase kinase-3β pathway (2008) (1)
- Determinants of tissue kallikrein cleavage specificity in the limited proteolysis of kininogens. (1992) (1)
- Chapter 624 – Mouse Kallikrein 9, Epidermal Growth Factor-binding Protein (2013) (1)
- Adenovirus-Mediated Delivery of Human Tissue Kallikrein Gene Reduces Blood Pressure in Goldblatt-Hypertensive Rats (1998) (1)
- Urinary prostasin excretion is associated with adiposity in nonhypertensive African-American adolescents (2013) (1)
- Role of the brain kallikrein-kinin system in the pathogenesis of genetic hypertension (1995) (1)
- Kallistatin antagonizes Wnt/β-catenin signaling and cancer cell motility via binding to low-density lipoprotein receptor-related protein 6 (2013) (1)
- The Kallikrein-Kinin System and Hypertension (2007) (1)
- Adenovirus-mediated gene transfer for cardiovascular and renal diseases. (2002) (1)
- G11 – Direct gene delivery of human tissue kallikrein reduces blood pressure in spontaneously hypertensive rats (1995) (1)
- Gene Therapy for Hypertension (2012) (1)
- Sexual dimorphism of blood pressure response to bradykinin (1997) (1)
- Gene therapy for hypertension: a review of potential targets. (1999) (1)
- Localization and secretion of tissue kallikrein in peptidoglycan-induced enterocolitis in Lewis rats. (1998) (1)
- Kallikrein and Kinins in Epithelial Ion Transport (1984) (0)
- Activation of Akt-GSK Signaling Adrenomedullin Protects Against Myocardial Apoptosis After Ischemia / Reperfusion (2003) (0)
- Rat Tissue Kallikrein (2013) (0)
- Human Tissue Kallikrein Gene Transfer Accelerates Spontaneous Angiogenesis Response to Ischemia (2000) (0)
- Mouse γ-Renin, Kallikrein 16 (2013) (0)
- Chapter 658 – Prostasin (2013) (0)
- Intestinal tissue kallikrein - kallistatin profile in patients with inflammatory bowel disease (2000) (0)
- Corrigendum (2000) (0)
- Kallistatinin Blood Pressure Regulation Transgenicand Somatic Gene DeliveryStudies (1997) (0)
- the bradykinin B1-receptor partecipates in the central regulation of blood pressure in spontaneously hypertensive rats (1998) (0)
- Tissue kallikrein gene therapy reduces blood pressure in spontaneously hypertensive rats (1994) (0)
- Basic Science and Experimental Studies Tissue Kallikrein and Kinin Infusion Rescues Failing Myocardium After Myocardial Infarction (2007) (0)
- Kallistatin in Sepsis: Protective Actions and Potential Therapeutic Applications (2017) (0)
- Mouse γ-nerve Growth Factor (2013) (0)
- 31 Kallikrein and esterase A localization in iontransporting epithelia. (1986) (0)
- Erratum: Adenovirus-mediated human tissue kallikrein gene delivery inhibits neontima formation induced by interruption of blood flow in mice (Arteriosclerosis, Thrombosis, and Vascular Biology (June 2000) (1459-1466)) (2000) (0)
- 果糖诱导大鼠胰岛素抵抗和高血压的机制及人组织型激肽释放酶基因的治疗作用 (2003) (0)
- Adenovirus-Mediated Human Kallikrein Gene Delivery Increases Endogenous Rat Tissue Kallikrein in Hypertensive Rat Models (2000) (0)
- Alterations in blood pressure control and cardiac pathophysiology in human tissue kallikrein transgenic fats (1998) (0)
- Direct radioimmunoassay of rat urinary kallikrein and comparison with other measures of urniary kallikrein activity. [/sup 125/I] (1979) (0)
- Mouse Proteinase A (2013) (0)
- Human Tissue Kallikrein Gene Delivery Attenuates Cardiac Glycogen Accumulation in Streptozotocin-Induced Diabetic Rats (2000) (0)
- Processing of apolipoprotein B-100 of human plasma low density lipoproteins by tissue and plasma kallikreins. (1986) (0)
- Kallistatin Inhibits Endothelial Cell Proliferation, Migration and Adhesion in Vitro and Angiogenesis in the Ischemic Hindlimb of Rats (2000) (0)
- Human Kallikrein-related Peptidase 3, the Prostate-specific Antigen (2013) (0)
- Effect of cyclosporin A on the expression of tissue kallikrein, kininogen, and bradykinin receptor in rat. (1997) (0)
- Central delivery of genes encoding for human tissue kallikrein or atrial natriuretic peptide reduces blood pressure in spontaneously hypertensive rats. (1998) (0)
- Chapter 626 – Mouse Proteinase F (2013) (0)
- Rapid Publication Kallistatin Is a Potent New Vasodilator (2013) (0)
- hypertensive rats and promotes neovascularization in spontaneously Kallikrein gene delivery attenuates cardiac remodeling (2016) (0)
- Lentivirus-mediated kallistatin gene transfer for the treatment of metastatic lung cancer (2008) (0)
- Role of the kallikrein kinin system in gestational hypertension. (1994) (0)
- Human Tissue Kallikrein Gene Transfer Rescue of Impaired Angiogenesis in Spontaneously Hypertensive Rats by Intramuscular (2001) (0)
- Results Effects of Tissue Kallikrein and B 1 and B 2 Receptor Antagonists on the Proliferation of Primary Cultured VSMCs (2000) (0)
- is a new inhibitor of angiogenesis and tumor growth (2002) (0)
- Adrenomedullin Gene Delivery Reduces in Spontaneously Hypertensive Blood Rats Pressure (2006) (0)
- Human Tissue Kallikrein Gene Transfer Induces Angiogenesis (2000) (0)
- Intestinal tissue kallikrein secretion in peptidoglycan-induced enterocolitis in Lewis rat (1997) (0)
- Over-expression of eNOS led to increased levels of nitrosylated proteins in the mouse livers. (2014) (0)
- [25] – Screening of Complementary DNA Library Using Radiolabeled Antigen (1995) (0)
- Pleiotropic Effects of Kallikrein-Kinin on Apoptosis, Inflammation and Angiogenesis in Cardiovascular Disease and Stroke (2003) (0)
- Screening of complementary DNA library using radiolabeled antigen. (1993) (0)
- Kallikrein Gene Delivery Attenuates Cardiac Remodeling after Myocardial Infarction through the Inhibition of Cardiac Apoptosis (2002) (0)
- Enzyme from Toad Bladder and Skin (1980) (0)
- Localization of tissue kallikrein in peptidoglycan-induced enterocolitis in Lewis rat: Further evidence for secretion (1998) (0)
- Rat Kallikrein 10, Salivary Gland Proteinase K (2013) (0)
- Experimental Approaches Using Kallikrein Gene Therapy for Hypertension (1997) (0)
- Differential interactions of human kallikrein-binding protein and ;,-antitrypsin with human tissue kallikrein (2005) (0)
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