Julie Forman-Kay
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Why Is Julie Forman-Kay Influential?
(Suggest an Edit or Addition)According to Wikipedia, Julie Forman-Kay is a scientist at the Hospital for Sick Children and professor at University of Toronto. Her research focuses on the dynamics, interactions, structures, and functions of intrinsically disordered proteins.
Julie Forman-Kay's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Backbone dynamics of a free and phosphopeptide-complexed Src homology 2 domain studied by 15N NMR relaxation. (1994) (1996)
- Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles (2015) (1135)
- Sensitivity of secondary structure propensities to sequence differences between α‐ and γ‐synuclein: Implications for fibrillation (2006) (597)
- Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques (1994) (503)
- A Gradient-Enhanced HCCH-TOCSY Experiment for Recording Side-Chain 1H and 13C Correlations in H2O Samples of Proteins (1993) (475)
- Slow dynamics in folded and unfolded states of an SH3 domain. (2001) (431)
- Folding of an intrinsically disordered protein by phosphorylation as a regulatory switch (2014) (423)
- Atomic-level characterization of disordered protein ensembles. (2007) (395)
- Protein dynamics and conformational disorder in molecular recognition (2009) (394)
- Pi-Pi contacts are an overlooked protein feature relevant to phase separation (2018) (391)
- Two-dimensional NMR experiments for correlating carbon-13.beta. and proton.delta./.epsilon. chemical shifts of aromatic residues in 13C-labeled proteins via scalar couplings (1993) (389)
- A heteronuclear correlation experiment for simultaneous determination of 15N longitudinal decay and chemical exchange rates of systems in slow equilibrium (1994) (379)
- Modulation of Intrinsically Disordered Protein Function by Post-translational Modifications (2016) (335)
- Dynamic equilibrium engagement of a polyvalent ligand with a single-site receptor (2008) (313)
- Sequence determinants of compaction in intrinsically disordered proteins. (2010) (311)
- Solution structure and dynamics of the outer membrane enzyme PagP by NMR (2002) (308)
- Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation (2017) (281)
- Sensitivity of secondary structure propensities to sequence differences between alpha- and gamma-synuclein: implications for fibrillation. (2006) (280)
- CFTR regulatory region interacts with NBD1 predominantly via multiple transient helices (2007) (279)
- Autoinhibition of the HECT-Type Ubiquitin Ligase Smurf2 through Its C2 Domain (2007) (270)
- Structure/function implications in a dynamic complex of the intrinsically disordered Sic1 with the Cdc4 subunit of an SCF ubiquitin ligase. (2010) (252)
- Comparison of the backbone dynamics of a folded and an unfolded SH3 domain existing in equilibrium in aqueous buffer. (1995) (247)
- Nuclear magnetic resonance structure of an SH2 domain of phospholipase C-γ1 complexed with a high affinity binding peptide (1994) (217)
- What’s in a name? Why these proteins are intrinsically disordered (2013) (216)
- Polyelectrostatic interactions of disordered ligands suggest a physical basis for ultrasensitivity (2007) (215)
- Simultaneous Acquisition of 15N- and 13C-Edited NOE Spectra of Proteins Dissolved in H2O (1994) (210)
- Calculation of ensembles of structures representing the unfolded state of an SH3 domain. (2001) (209)
- Solution structure of a Nedd4 WW domain–ENaC peptide complex (2001) (209)
- RGG/RG Motif Regions in RNA Binding and Phase Separation. (2018) (207)
- pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins (2013) (196)
- From sequence and forces to structure, function, and evolution of intrinsically disordered proteins. (2013) (193)
- Phosphoregulated FMRP phase separation models activity-dependent translation through bidirectional control of mRNA granule formation (2019) (188)
- Correlation between dynamics and high affinity binding in an SH2 domain interaction. (1996) (186)
- Phospho-dependent phase separation of FMRP and CAPRIN1 recapitulates regulation of translation and deadenylation (2019) (177)
- Properties of Stress Granule and P-Body Proteomes. (2019) (168)
- Distribution of molecular size within an unfolded state ensemble using small-angle X-ray scattering and pulse field gradient NMR techniques. (2002) (166)
- Structure and disorder in an unfolded state under nondenaturing conditions from ensemble models consistent with a large number of experimental restraints. (2009) (159)
- A simple in vivo assay for increased protein solubility (1999) (156)
- Sequence-Specific Polyampholyte Phase Separation in Membraneless Organelles. (2016) (153)
- Structural characterization of folded and unfolded states of an SH3 domain in equilibrium in aqueous buffer. (1995) (153)
- NOE data demonstrating a compact unfolded state for an SH3 domain under non-denaturing conditions. (1999) (149)
- Characterization of disordered proteins with ENSEMBLE (2013) (149)
- Structural characterization of proteins with an attached ATCUN motif by paramagnetic relaxation enhancement NMR spectroscopy. (2001) (148)
- Dynamic Protein Interaction Networks and New Structural Paradigms in Signaling. (2016) (140)
- Theories for Sequence-Dependent Phase Behaviors of Biomolecular Condensates. (2018) (140)
- Liquid-liquid phase separation in cellular signaling systems. (2016) (139)
- Diversity in protein recognition by PTB domains. (1999) (138)
- High-resolution three-dimensional structure of reduced recombinant human thioredoxin in solution. (1992) (131)
- Regulatory R region of the CFTR chloride channel is a dynamic integrator of phospho-dependent intra- and intermolecular interactions (2013) (130)
- Characterization of the backbone dynamics of folded and denatured states of an SH3 domain. (1997) (129)
- Global folds of proteins with low densities of NOEs using residual dipolar couplings: application to the 370-residue maltodextrin-binding protein. (2000) (126)
- Multidimensional NMR Methods for Protein Structure Determination (2001) (119)
- NMR studies of unfolded states of an SH3 domain in aqueous solution and denaturing conditions. (1997) (118)
- Structure of a Numb PTB domain–peptide complex suggests a basis for diverse binding specificity (1998) (117)
- Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A (1999) (116)
- Improved structural characterizations of the drkN SH3 domain unfolded state suggest a compact ensemble with native-like and non-native structure. (2007) (115)
- Contributions to protein entropy and heat capacity from bond vector motions measured by NMR spin relaxation. (1997) (115)
- Correlation between binding and dynamics at SH2 domain interfaces (1998) (111)
- Finding Our Way in the Dark Proteome. (2016) (110)
- Ensemble modeling of protein disordered states: Experimental restraint contributions and validation (2011) (109)
- NMR evidence for differential phosphorylation‐dependent interactions in WT and ΔF508 CFTR (2010) (103)
- Structural diversity in free and bound states of intrinsically disordered protein phosphatase 1 regulators. (2010) (103)
- A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases (2006) (100)
- Transient structure and dynamics in the disordered c-Myc transactivation domain affect Bin1 binding (2012) (99)
- Relationship between electrostatics and redox function in human thioredoxin: characterization of pH titration shifts using two-dimensional homo- and heteronuclear NMR. (1992) (98)
- Probing the diverse landscape of protein flexibility and binding. (2012) (96)
- A ‘three‐pronged’ binding mechanism for the SAP/SH2D1A SH2 domain: structural basis and relevance to the XLP syndrome (2002) (94)
- Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb (2000) (92)
- Affinity and Specificity of Interactions between Nedd4 Isoforms and the Epithelial Na+ Channel* (2003) (90)
- Comparative roles of charge, π, and hydrophobic interactions in sequence-dependent phase separation of intrinsically disordered proteins (2020) (87)
- Complex regulatory mechanisms mediated by the interplay of multiple post-translational modifications. (2018) (86)
- Similarities between the spectrin SH3 domain denatured state and its folding transition state. (2000) (82)
- Structural determinants for high-affinity binding in a Nedd4 WW3* domain-Comm PY motif complex. (2006) (82)
- The 'dynamics' in the thermodynamics of binding (1999) (81)
- Proteome-wide signatures of function in highly diverged intrinsically disordered regions (2019) (81)
- First-generation predictors of biological protein phase separation. (2019) (79)
- Phase Separation as a Missing Mechanism for Interpretation of Disease Mutations (2020) (78)
- Triple-resonance NOESY-based experiments with improved spectral resolution: Applications to structural characterization of unfolded, partially folded and folded proteins (1997) (78)
- Site-specific contributions to the pH dependence of protein stability (2003) (78)
- Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide (2002) (76)
- Interaction of the eukaryotic initiation factor 4E with 4E-BP2 at a dynamic bipartite interface. (2013) (76)
- Targeting Intrinsically Disordered Transcription Factors: Changing the Paradigm. (2018) (75)
- Charge pattern matching as a ‘fuzzy’ mode of molecular recognition for the functional phase separations of intrinsically disordered proteins (2017) (74)
- Aromatic and methyl NOEs highlight hydrophobic clustering in the unfolded state of an SH3 domain. (2003) (72)
- Random-phase-approximation theory for sequence-dependent, biologically functional liquid-liquid phase separation of intrinsically disordered proteins (2016) (72)
- Calculation of residual dipolar couplings from disordered state ensembles using local alignment. (2008) (71)
- Direct Binding of the Corrector VX-809 to Human CFTR NBD1: Evidence of an Allosteric Coupling between the Binding Site and the NBD1:CL4 Interface (2017) (70)
- NMR PULSE SCHEMES FOR THE SEQUENCE-SPECIFIC ASSIGNMENT OF ARGININE GUANIDINO 15N AND 1H CHEMICAL SHIFTS IN PROTEINS (1995) (69)
- Coupling of tandem Smad ubiquitination regulatory factor (Smurf) WW domains modulates target specificity (2010) (69)
- Measurement of side-chain carboxyl pK(a) values of glutamate and aspartate residues in an unfolded protein by multinuclear NMR spectroscopy. (2002) (68)
- Sequential assignment of proline-rich regions in proteins: Application to modular binding domain complexes (2000) (68)
- Conformational ensembles of an intrinsically disordered protein consistent with NMR, SAXS and single-molecule FRET. (2020) (66)
- Congenital Chloride-losing Diarrhea Causing Mutations in the STAS Domain Result in Misfolding and Mistrafficking of SLC26A3* (2008) (66)
- High-affinity binding of the Drosophila Numb phosphotyrosine-binding domain to peptides containing a Gly-Pro-(p)Tyr motif. (1997) (66)
- Dramatic stabilization of an SH3 domain by a single substitution: roles of the folded and unfolded states. (2001) (65)
- Characterization of the PilN, PilO and PilP type IVa pilus subcomplex (2011) (65)
- The Ubiquitin Binding Region of the Smurf HECT Domain Facilitates Polyubiquitylation and Binding of Ubiquitylated Substrates* (2009) (65)
- Synuclein-gamma targeting peptide inhibitor that enhances sensitivity of breast cancer cells to antimicrotubule drugs. (2007) (62)
- Studies on the solution conformation of human thioredoxin using heteronuclear 15N-1H nuclear magnetic resonance spectroscopy. (1990) (62)
- An Expanded WW Domain Recognition Motif Revealed by the Interaction between Smad7 and the E3 Ubiquitin Ligase Smurf2* (2006) (61)
- Analysis of deuterium relaxation-derived methyl axis order parameters and correlation with local structure (1999) (61)
- Cooperative interactions and a non-native buried Trp in the unfolded state of an SH3 domain. (2002) (61)
- Composite low affinity interactions dictate recognition of the cyclin-dependent kinase inhibitor Sic1 by the SCFCdc4 ubiquitin ligase (2012) (60)
- 15NH/D-SOLEXSY experiment for accurate measurement of amide solvent exchange rates: application to denatured drkN SH3 (2010) (59)
- Structural changes of CFTR R region upon phosphorylation: a plastic platform for intramolecular and intermolecular interactions (2013) (57)
- Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia (2017) (56)
- Solution structure of a polypeptide dimer comprising the fourth Ca(2+)-binding site of troponin C by nuclear magnetic resonance spectroscopy. (1991) (54)
- Phase Separation in Biology and Disease. (2018) (53)
- Phosphorylation-dependent 14-3-3 protein interactions regulate CFTR biogenesis (2012) (52)
- The effect of intrachain electrostatic repulsion on conformational disorder and dynamics of the Sic1 protein. (2014) (51)
- PED in 2021: a major update of the protein ensemble database for intrinsically disordered proteins (2020) (51)
- Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions. (2020) (49)
- High populations of non-native structures in the denatured state are compatible with the formation of the native folded state. (1998) (48)
- Conformational Changes Relevant to Channel Activity and Folding within the first Nucleotide Binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator* (2012) (48)
- Structural and dynamic characterization of the phosphotyrosine binding region of a Src homology 2 domain--phosphopeptide complex by NMR relaxation, proton exchange, and chemical shift approaches. (1995) (46)
- Comprehensive NOE characterization of a partially folded large fragment of staphylococcal nuclease Delta131Delta, using NMR methods with improved resolution. (1997) (46)
- Identification of a molecular locus for normalizing dysregulated GABA release from interneurons in the Fragile X brain (2018) (43)
- Structural signature of the MYPT1-PP1 interaction. (2011) (43)
- Synergy of cAMP and calcium signaling pathways in CFTR regulation (2017) (42)
- pH Titration studies of an SH2 domain‐phosphopeptide complex: Unusual histidine and phosphate pKa values (1997) (42)
- 19F NMR studies of solvent exposure and peptide binding to an SH3 domain. (2007) (42)
- Determination of the positions of bound water molecules in the solution structure of reduced human thioredoxin by heteronuclear three-dimensional nuclear magnetic resonance spectroscopy. (1991) (41)
- NMR characterization of copper-binding domains 4-6 of ATP7B . (2010) (40)
- Side-chain dynamics of the SAP SH2 domain correlate with a binding hot spot and a region with conformational plasticity. (2002) (39)
- Interactions between the three CIN85 SH3 domains and ubiquitin: implications for CIN85 ubiquitination. (2008) (36)
- Identification and characterization of human genes encoding Hprp3p and Hprp4p, interacting components of the spliceosome. (1997) (35)
- 1H-13C DIPOLE-DIPOLE CROSS-CORRELATED SPIN RELAXATION AS A PROBE OF DYNAMICS IN UNFOLDED PROTEINS : APPLICATION TO THE DRKN SH3 DOMAIN (1999) (35)
- Structural comparison of the unstable drkN SH3 domain and a stable mutant. (2005) (34)
- Tryptophan solvent exposure in folded and unfolded states of an SH3 domain by 19F and 1H NMR. (2006) (34)
- Structural, Functional, and Bioinformatic Studies Demonstrate the Crucial Role of an Extended Peptide Binding Site for the SH3 Domain of Yeast Abp1p* (2009) (34)
- Interaction hot spots for phase separation revealed by NMR studies of a CAPRIN1 condensed phase (2021) (33)
- An allosteric conduit facilitates dynamic multisite substrate recognition by the SCFCdc4 ubiquitin ligase (2017) (33)
- NMR experiments for studies of dilute and condensed protein phases: Application to the phase-separating protein CAPRIN1. (2020) (32)
- Hydration and packing along the folding pathway of SH3 domains by pressure-dependent NMR. (2006) (32)
- Oxygen as a paramagnetic probe of clustering and solvent exposure in folded and unfolded states of an SH3 domain. (2007) (30)
- Entropy and Information within Intrinsically Disordered Protein Regions (2019) (30)
- Allosteric Coupling between the Intracellular Coupling Helix 4 and Regulatory Sites of the First Nucleotide-binding Domain of CFTR (2013) (30)
- Differential Dynamic Engagement within 24 SH3 Domain: Peptide Complexes Revealed by Co-Linear Chemical Shift Perturbation Analysis (2012) (29)
- NMR structure of neuromedin C, a neurotransmitter with an amino terminal CuII-, NiII-binding (ATCUN) motif. (2009) (29)
- NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain. (2005) (27)
- Dynamics intrinsic to cystic fibrosis transmembrane conductance regulator function and stability. (2013) (26)
- Extended experimental inferential structure determination method in determining the structural ensembles of disordered protein states (2020) (26)
- The ZIP5 Ectodomain Co-Localizes with PrP and May Acquire a PrP-Like Fold That Assembles into a Dimer (2013) (25)
- FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation (2020) (24)
- Binding screen for cystic fibrosis transmembrane conductance regulator correctors finds new chemical matter and yields insights into cystic fibrosis therapeutic strategy (2016) (23)
- Conformations of a Metastable SH3 Domain Characterized by smFRET and an Excluded-Volume Polymer Model. (2016) (23)
- Systematic identification of conditionally folded intrinsically disordered regions by AlphaFold2 (2022) (23)
- NMR studies of tandem WW domains of Nedd4 in complex with a PY motif-containing region of the epithelial sodium channel. (1998) (23)
- Disorder in a Target for the Smad2 Mad Homology 2 Domain and Its Implications for Binding and Specificity* (2004) (21)
- NMR studies of tandem WW domains of Nedd4 in complex with a PY motif-containing region of the epithelial sodium channel (1998) (21)
- Identifying molecular features that are associated with biological function of intrinsically disordered protein regions (2020) (21)
- A proton nuclear magnetic resonance assignment and secondary structure determination of recombinant human thioredoxin. (1989) (21)
- Megakaryocyte and platelet abnormalities in a patient with a W33C mutation in the conserved SH3-like domain of myosin heavy chain IIA (2009) (20)
- Multivalent Interactions with Fbw7 and Pin1 Facilitate Recognition of c-Jun by the SCFFbw7 Ubiquitin Ligase. (2018) (19)
- CFTR structure. (2018) (18)
- Interplay of buried histidine protonation and protein stability in prion misfolding (2017) (18)
- Characterization of the Phosphotyrosine-binding Domain of the Drosophila Shc Protein* (1996) (18)
- Molecular oxygen as a paramagnetic NMR probe of protein solvent exposure and topology (2008) (17)
- Deletion of Phenylalanine 508 in the First Nucleotide-binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Increases Conformational Exchange and Inhibits Dimerization*♦ (2015) (15)
- Phosphorylation-dependent regulation of messenger RNA transcription, processing and translation within biomolecular condensates. (2021) (15)
- Stabilization of a nucleotide-binding domain of the cystic fibrosis transmembrane conductance regulator yields insight into disease-causing mutations (2017) (14)
- Clinical presentation and molecular basis of congenital antithrombin deficiency in children: a cohort study (2014) (14)
- NMR spectroscopy to study the dynamics and interactions of CFTR. (2011) (12)
- Measuring pK(a) values in protein folding transition state ensembles by NMR spectroscopy. (2005) (11)
- Characterization of the hydrodynamic properties of the folding transition state of an SH3 domain by magnetization transfer NMR spectroscopy. (2006) (11)
- Recessive NOS1AP variants impair actin remodeling and cause glomerulopathy in humans and mice (2021) (11)
- Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition (2020) (11)
- Title : PiPi Contacts Are An Overlooked Protein Feature Relevant To Phase Separation (2018) (11)
- Structural studies of FF domains of the transcription factor CA150 provide insights into the organization of FF domain tandem arrays. (2009) (11)
- Developmental Dynamics of RNA Translation in the Human Brain (2021) (10)
- O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics. (2021) (10)
- An evolutionary switch in ND2 enables Src kinase regulation of NMDA receptors (2017) (9)
- Discovering molecular features of intrinsically disordered regions by using evolution for contrastive learning (2021) (8)
- Translating Material Science into Biological Function. (2019) (8)
- Illuminating the Dark Proteome (2016) (8)
- What are the distinguishing features and size requirements of biomolecular condensates and their implications for RNA-containing condensates? (2021) (8)
- Configurational Entropy of Folded Proteins and Its Importance for Intrinsically Disordered Proteins (2020) (7)
- In support of the BMRB (2012) (7)
- Augmentation of CFTR function in human bronchial epithelial cells via SLC6A14-dependent amino acid uptake: Implications for treatment of Cystic Fibrosis. (2019) (7)
- Mapping the per-residue surface electrostatic potential of CAPRIN1 along its phase-separation trajectory (2022) (7)
- Structural and dynamic characterization of an SH2 domain-phosphopeptide complex by NMR approaches. (1995) (7)
- An Interpretable Machine-Learning Algorithm to Predict Disordered Protein Phase Separation Based on Biophysical Interactions (2022) (7)
- A New Phase in ALS Research. (2016) (6)
- Whence Blobs? Phylogenetics of functional protein condensates. (2020) (6)
- The Structural Signature of the MYPT 1 : PP 1 Interaction (2011) (6)
- Role of CBS and Bateman Domains in Phosphorylation-Dependent Regulation of a CLC Anion Channel. (2016) (5)
- IDPConformerGenerator: A Flexible Software Suite for Sampling the Conformational Space of Disordered Protein States (2022) (5)
- Integrating multiple experimental data to determine conformational ensembles of an intrinsically disordered protein (2020) (5)
- Extended Experimental Inferential Structure Determination Method for Evaluating the Structural Ensembles of Disordered Protein States (2019) (4)
- Author response: Pi-Pi contacts are an overlooked protein feature relevant to phase separation (2018) (4)
- A recurrent SHANK3 frameshift variant in Autism Spectrum Disorder (2021) (4)
- Molecular biology: A hidden competitive advantage of disorder (2017) (4)
- Integrating smFRET, SAXS and NMR data to infer structural ensembles of an intrinsically-disordered protein (2020) (4)
- Global Proximity Interactome of the Human Macroautophagy Pathway (2021) (4)
- SOLUTION STRUCTURE OF THE RNEDD4 WWIII DOMAIN-RENAL BP2 PEPTIDE COMPLEX (2001) (4)
- Molecular structural analysis of a novel and de‐novo mutation in the SERPINC1 gene associated with type 1 antithrombin deficiency (2017) (3)
- Development and characterization of synthetic antibodies binding to the cystic fibrosis conductance regulator (2016) (3)
- Protein Dynamics to Define and Refine Disordered Protein Ensembles. (2022) (3)
- Structure and Function Implications of Conformational Ensembles Consistent with NMR, SAXS, and smFRET Data. The Disordered Protein SIC1 Before and After Multisite Phosphorylation (2020) (3)
- c.1058C>T variant in the SERPINC1 gene is pathogenic for antithrombin deficiency (2015) (2)
- O-GlcNAcylation reduces phase separation and aggregation of the EWS N-terminal low complexity region (2021) (2)
- Learning to evolve structural ensembles of unfolded and disordered proteins using experimental solution data. (2022) (2)
- The Conformations of the DrkN SH3 Domain Studied by Single Molecule Fluorescence Spectroscopy (2014) (2)
- NMR insights into dynamic, multivalent interactions of intrinsically disordered regions: from discrete complexes to condensates (2022) (2)
- Faculty Opinions recommendation of LLPSDB: a database of proteins undergoing liquid–liquid phase separation in vitro. (2019) (2)
- "Fuzzy" complexes: How much disorder can a biologically relevant complex tolerate, and can it even be beneficial? (2010) (2)
- Dynamic complexes of intrinsically disordered proteins and their regulation by post‐translational modifications (2013) (1)
- Multisite Phosphorylation and Binding Alter Conformational Dynamics of the 4E-BP2 Protein (2022) (1)
- A spatiotemporal reconstruction of the C. elegans pharyngeal cuticle reveals a structure rich in phase-separating proteins (2022) (1)
- Exploration of O-GlcNAc-transferase (OGT) glycosylation sites reveals a target sequence compositional bias (2022) (1)
- Oxidative Inhibition of Pbp1 Phase Separation. (2019) (1)
- Surface electrostatics dictate RNA-binding protein CAPRIN1 condensate concentration and hydrodynamic properties (2022) (1)
- Phase Separation of Disordered Protein in the Formation of Membrane-Less Organelles (2014) (1)
- Ternary complex of an Crk SH2 domain, Crk-derived phophopeptide, and Abl SH3 domain by NMR spectroscopy (2002) (1)
- Integrating NMR, SAXS and Single-Molecule FRET Data to Infer Conformational Ensembles of the Yeast Sic1 Protein (2021) (1)
- Learning Correlations between Internal Coordinates to Improve 3D Cartesian Coordinates for Proteins. (2022) (1)
- 1 H and 15 N resonance assignments and secondary structure of the human thioredoxin C 62 A , C 69 A , C 73 A mutant (2005) (1)
- Corrigendum to “Random-phase-approximation theory for sequence-dependent, biologically functional liquid-liquid phase separation of intrinsically disordered proteins” [J. Mol. Liq. 228 (2017) 176–193] (2019) (1)
- Mechanisms Of Biological Regulation By Highly Dynamic Protein Complexes (2009) (0)
- Multimodal interactions between a disordered protein and its folded target at single-molecule level. (2023) (0)
- Folded Proteins Inform the Development of Models for Intrinsically Disordered Proteins (2020) (0)
- How Electrostatics Influences the Conformational Disorder and Dynamics of the Sic1 Protein: A Single-Molecule Study (2014) (0)
- Non-cooperative 4E-BP2 folding with exchange between eIF4E-binding and binding-incompatible states tunes cap-dependent translation inhibition (2020) (0)
- Modelling the Multifarious Conformations of the Intrinsically Disordered Protein 4E-BP2 with sm-FRET, SAXS & PRE Restraints (2021) (0)
- Solution Structure of PilP from Pseudomonas aeruginosa (2011) (0)
- Rabbit Prp 90-231 NH assignments (2017) (0)
- Solution Structure of Smurf2 WW2 and WW3 bound to Smad7 PY motif containing peptide (2010) (0)
- Protein Structure and Biology (2013) (0)
- Integrating the Signals: Implications of CFTR NBD1 Allostery to Cystic Fibrosis (2014) (0)
- Transient structure and intrinsic disorder in the c-Myc transactivation domain and its effects on ligand binding (2011) (0)
- Examining the Nanosecond-to-Millisecond Dynamics of Sic1 by Fluorescence Techniques (2018) (0)
- Phenotypic profiling of CFTR modulators in patient-derived respiratory epithelia (2017) (0)
- Solution Structure of the C2 domain of human Smurf2 (2007) (0)
- Backbone 1H, 13C and 15N Chemical Shift Assignments for c-Jun (2017) (0)
- Single-Molecule Dissection of the Conformations, Dynamics and Binding of the Disordered 4E-BP2 Protein (2016) (0)
- dNumb PTB Domain Complexed with a Phosphotyrosine Peptide, NMR, Ensemble of Structures. (1999) (0)
- Structural and energetic insights into CF-causing mutations in CFTR (2018) (0)
- SAP/SH2D1A bound to peptide n-pY (2001) (0)
- Solution Structure of the dNedd4 WW3* Domain- Comm LPSY Peptide Complex (2006) (0)
- Single Molecule FRET Investigation of the Dimensions and Dynamics in Highly Cooperative Sic1-WD40 Binding (2017) (0)
- Solution NMR structure of the outer membrane enzyme PagP in DPC micelles (2002) (0)
- Electrostatics and Intrinsic Disorder: A Single-Molecule Study of the Sic1 Protein (2012) (0)
- Solution structure of Smurf2 WW3 domain-Smad7 PY peptide complex (2006) (0)
- NMR structure of Phosphorylated 4E-BP2 (2015) (0)
- Aberrant phase separation: linking IDR mutations to disease. (2023) (0)
- Computational design of intrinsically disordered protein regions by matching bulk molecular properties (2023) (0)
- Experimental and computational characterization of disordered states of proteins (2011) (0)
- GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN USING PEPTIDE ORIENTATIONS FROM DIPOLAR COUPLINGS (2001) (0)
- Faculty Opinions recommendation of Multiple Weak Linear Motifs Enhance Recruitment and Processivity in SPOP-Mediated Substrate Ubiquitination. (2016) (0)
- Electrostatics of salt-dependent re-entrant phase behaviors highlights diverse roles of ATP in biomolecular condensates. (2023) (0)
- Faculty Opinions recommendation of The RNA-binding protein fused in sarcoma (FUS) functions downstream of poly(ADP-ribose) polymerase (PARP) in response to DNA damage. (2018) (0)
- Faculty Opinions recommendation of PhaSepDB: a database of liquid-liquid phase separation related proteins. (2019) (0)
- Beyond disorder: An integrative investigation of the intrinsically disordered protein 4E-BP2. (2023) (0)
- Conformational Dynamics and Multimerization of Active Forms of the EphrinB Receptor 2 Kinase Domain (2015) (0)
- Dynamic Interactions between a Disordered Protein and its Target at the Single-Molecule Level (2019) (0)
- Role of the STAS domain of the E . coli anion transporter (2013) (0)
- A crucial role for high intrinsic specificity in the function of yeast SH3 domains (2009) (0)
- Backbone 1H, 13C, and 15N Chemical Shift Assignments for T22G mutant of N-terminal SH3 domain of the Drosophila protein drk (2006) (0)
- 1H, 13C and 15N Backbone Resonance Assignments of the Nonphosphorylated CFTR Regulatory Region (2007) (0)
- Reviewers Acknowledgement (2020) (0)
- Global Dimensions are Decoupled from Electrostatics in the Intrinsically Disordered Protein Sic1 (2018) (0)
- SOLUTION STRUCTURE OF THE NUMB PTB DOMAIN COMPLEXED TO A NAK PEPTIDE (2000) (0)
- Crystal structure of nucleotide-binding domain 2 (NBD2) of the human Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) (2020) (0)
- Solution structure of the T22G mutant of N-terminal SH3 domain of DRK (DRKN SH3 DOMAIN) (2005) (0)
- Chemical Shift Assignments and Coupling Constants for the rat Nedd4 WWIII domain - rat ENaC bP2 Peptide Complex (2001) (0)
- Energetics of π-π Interactions Implicated in Liquid-Liquid Phase Separation (2020) (0)
- Platform: Membrane Protein Structure, Dynamics, and Interactions (2014) (0)
- Local Chain Dynamics of Intrinsically Disordered Sic1 Protein Inferred from Fluorescence Anisotropy Decay Measurements (2019) (0)
- Probing the Conformational Dynamics of the Disordered 4E-BP2 Protein in Different Phosphorylation States using Single-Molecule Fluorescence (2018) (0)
- Dimensions and Dynamics of Highly Cooperative Sic1-WD40 Binding: smFRET through a Polymer Physics Lens (2016) (0)
- The Role of Dynamic Protein Complexes in the Ubiquitin-Proteasome Pathway (2011) (0)
- GLOBAL FOLD OF MALTODEXTRIN BINDING PROTEIN COMPLEXED WITH BETA-CYCLODEXTRIN (2001) (0)
- The Intrinsically Unstable SH3-DRKN Protein: Compactness, Conformations and Speed (2013) (0)
- Assignment and structural characterization of intrinsically disordered CDK inhibitor phosphoSic1 from yeast (2010) (0)
- An intrinsically disordered proteins community for ELIXIR (2020) (0)
- Interplay of buried histidine protonation and protein stability in prion misfolding (2017) (0)
- 1H, 15N, 13C', 13CA and 13CB Chemical Shift Assignments of intrinsically disordered gamma-synuclein (2006) (0)
- PTB (Phosphotyrosine‐Binding) Domains (2002) (0)
- NMR structure of the N-terminal SH3 domain of Drk (calculated without NOE restraints) (2005) (0)
- Polymer Theory for Sequence-Specific Phase Separation Behaviors of Charged Intrinsically Disordered Proteins (2019) (0)
- 1H, 13C, and 15N Backbone Assignments and 13C Aliphatic Sidechain Assignments for PKA Phosphorylated CFTR Regulatory Region (2007) (0)
- Solution structure of the T22G mutant of N-terminal SH3 domain of DRK (calculated without NOEs) (2005) (0)
- Faculty Opinions recommendation of PhaSePro: the database of proteins driving liquid-liquid phase separation. (2019) (0)
- Evidence for differential phosphorylationdependent phosphorylationdependent phosphorylationdependent interactions in WT and ∆ F 508 CFTR (2009) (0)
- Solution structure of the N-terminal SH3 domain of DRK (2005) (0)
- Conformational Heterogeneity and Theory of Sequence-Specific Functional Phase Separation of Intrinsically Disordered Proteins (2018) (0)
- Issue information (2023) (0)
- OP-NARE130962 326..335 (2013) (0)
- Idpconformergenerator: A flexible software suite for sampling the conformational space of disordered protein states. (2023) (0)
- Allosteric Coupling Between the CFTR Chloride Channel's NBD1 Heterodimer Interface and Intracellular Domains (2012) (0)
- Electrostatics-Dependent Shape of the Intrinsically-Disordered Protein Sic1 (2014) (0)
- Running title : Reassessment of NOEs in an unfolded SH 3 domain Title : Reassessment of NOE data for the unfolded state of an SH 3 domain highlights residual β-structure (2005) (0)
- Transitions in the framework of condensate biology. (2023) (0)
- Faculty Opinions recommendation of RNA pol II length and disorder enable cooperative scaling of transcriptional bursting. (2020) (0)
- Title Finding Our Way in the Dark Proteome Permalink (2016) (0)
- Random-phase-approximation theory for sequence-dependent behaviors of intrinsically disordered proteins in liquid-liquid phase separation (2017) (0)
- Faculty Opinions recommendation of Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. (2019) (0)
- Faculty Opinions recommendation of Citrullination of RGG motifs in FET proteins by PAD4 regulates protein aggregation and ALS susceptibility. (2018) (0)
- Theoretical Perspectives on Cellular Compartmentalization by Phase Separation (2019) (0)
- Phase Separation: Prediction and Role in Biological Regulation (2019) (0)
- Structural, Dynamic, and Folding Studies of SH2 and SH3 Domains (1996) (0)
- Crystal Structure of ScSkp1-ScCdc4-pSic1 peptide complex (2003) (0)
- Interplay Among Binding, Phosphorylation and Denaturation in Disordered 4E-BP2 as Probed by Single Molecule Fluorescence (2017) (0)
- A recurrent SHANK3 frameshift variant in Autism Spectrum Disorder (2021) (0)
- CIN85 Sh3-C domain in complex with ubiquitin (2008) (0)
- A Proton Nuclear Magnetic Resonance Assignment and Secondary Structure Determination of Recombinant Human Thioredoxint (2001) (0)
- Solution structure of CA150 FF1 domain and FF1-FF2 interdomain linker (2009) (0)
- Size, Shape and Motions of the SH3 Domain of the Drosophila Adapter Protein Drk (2012) (0)
- Phosphorylated 4E-BP2 (2014) (0)
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