Ilkka Julkunen

Q: What Schools Are Affiliated With Ilkka Julkunen

Ilkka Julkunen is affiliated with the following schools: University of Turku, University of Helsinki

Ilkka Julkunen's AcademicInfluence.com Rankings

Ilkka Julkunen

Physics

#6321

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#8251

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Physics

Ilkka Julkunen's Degrees

PhD Physics University of Helsinki
Masters Physics University of Helsinki

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Ilkka Julkunen's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme. (1995) (1186)
Maturation, Activation, and Protection of Dendritic Cells Induced by Double-stranded RNA (1999) (838)
Distinct patterns and kinetics of chemokine production regulate dendritic cell function (1999) (761)
Viral infection and Toll‐like receptor agonists induce a differential expression of type I and λ interferons in human plasmacytoid and monocyte‐derived dendritic cells (2004) (495)
AS03 Adjuvanted AH1N1 Vaccine Associated with an Abrupt Increase in the Incidence of Childhood Narcolepsy in Finland (2012) (476)
Infection of Human Macrophages and Dendritic Cells with Mycobacterium tuberculosis Induces a Differential Cytokine Gene Expression That Modulates T Cell Response1 (2001) (476)
Increased Incidence and Clinical Picture of Childhood Narcolepsy following the 2009 H1N1 Pandemic Vaccination Campaign in Finland (2012) (395)
Lactobacilli and Streptococci Induce Interleukin-12 (IL-12), IL-18, and Gamma Interferon Production in Human Peripheral Blood Mononuclear Cells (1998) (380)
Molecular pathogenesis of influenza A virus infection and virus-induced regulation of cytokine gene expression. (2001) (364)
IL-21 in Synergy with IL-15 or IL-18 Enhances IFN-γ Production in Human NK and T Cells1 (2003) (349)
IFNs activate toll-like receptor gene expression in viral infections (2001) (308)
Virus infection activates IL-1 beta and IL-18 production in human macrophages by a caspase-1-dependent pathway. (1999) (299)
Influenza A virus-induced IFN-alpha/beta and IL-18 synergistically enhance IFN-gamma gene expression in human T cells. (1998) (283)
Inflammatory responses in influenza A virus infection. (2000) (277)
IFN Regulatory Factor Family Members Differentially Regulate the Expression of Type III IFN (IFN-λ) Genes1 (2007) (264)
Interferon- Activates Multiple STAT Proteins and Upregulates Proliferation-Associated IL-2R, c-myc, and pim-1 Genes in Human T Cells (1999) (252)
IL-21 Up-Regulates the Expression of Genes Associated with Innate Immunity and Th1 Response1 (2002) (251)
NF-κB Is Transported into the Nucleus by Importin α3 and Importin α4* (2005) (247)
Negative Regulation of the Retinoic Acid-inducible Gene I-induced Antiviral State by the Ubiquitin-editing Protein A20* (2006) (239)
Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKε Molecular Complex from the Mitochondrial Outer Membrane by Hepatitis C Virus NS3-4A Proteolytic Cleavage (2006) (230)
Identification of Distinct Signaling Pathways Leading to the Phosphorylation of Interferon Regulatory Factor 3* (2001) (225)
Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2 (2015) (223)
Narcolepsy as an autoimmune disease: the role of H1N1 infection and vaccination (2014) (220)
Interferons up-regulate STAT1, STAT2, and IRF family transcription factor gene expression in human peripheral blood mononuclear cells and macrophages. (1997) (220)
Probiotic intervention has strain-specific anti-inflammatory effects in healthy adults. (2008) (216)
Expression and Replication of the Influenza Virus Genome (1989) (215)
Streptococcus pyogenes and Lactobacillus rhamnosus differentially induce maturation and production of Th1‐type cytokines and chemokines in human monocyte‐derived dendritic cells (2004) (207)
IL-21 in synergy with IL-15 or IL-18 enhances IFN-gamma production in human NK and T cells. (2003) (202)
IFN-α Regulates TLR-Dependent Gene Expression of IFN-α, IFN-β, IL-28, and IL-291 (2005) (198)
Importin α Nuclear Localization Signal Binding Sites for STAT1, STAT2, and Influenza A Virus Nucleoprotein* (2003) (195)
COVID-19 mRNA vaccine induced antibody responses against three SARS-CoV-2 variants (2021) (194)
Gene Expression and Antiviral Activity of Alpha/Beta Interferons and Interleukin-29 in Virus-Infected Human Myeloid Dendritic Cells (2005) (194)
Activation of TBK1 and IKKε Kinases by Vesicular Stomatitis Virus Infection and the Role of Viral Ribonucleoprotein in the Development of Interferon Antiviral Immunity (2004) (194)
Lactobacilli and Streptococci Activate NF-κB and STAT Signaling Pathways in Human Macrophages1 (2000) (193)
Nuclear and Nucleolar Targeting of Influenza A Virus NS1 Protein: Striking Differences between Different Virus Subtypes (2007) (191)
High frequency of cross-reacting antibodies against 2009 pandemic influenza A(H1N1) virus among the elderly in Finland. (2010) (188)
Induction of cytokine expression by herpes simplex virus in human monocyte-derived macrophages and dendritic cells is dependent on virus replication and is counteracted by ICP27 targeting NF-kappaB and IRF-3. (2006) (186)
IFN regulatory factor family members differentially regulate the expression of type III IFN (IFN-lambda) genes. (2007) (184)
Arginine/Lysine-rich Nuclear Localization Signals Mediate Interactions between Dimeric STATs and Importin α5* (2002) (184)
Human B‐cell epitopes of puumala virus nucleocapsid protein, the major antigen in early serological response (1995) (182)
IFN-α and IL-12 Induce IL-18 Receptor Gene Expression in Human NK and T Cells1 (2000) (177)
Virus-Infection or 5′ppp-RNA Activates Antiviral Signal through Redistribution of IPS-1 Mediated by MFN1 (2010) (176)
Multiple signaling pathways contribute to synergistic TLR ligand‐dependent cytokine gene expression in human monocyte‐derived macrophages and dendritic cells (2009) (174)
IFN‐α and IL‐18 synergistically enhance IFN‐γ production in human NK cells: differential regulation of Stat4 activation and IFN‐γ gene expression by IFN‐α and IL‐12 (2001) (174)
IFN-α Enhances TLR3-Mediated Antiviral Cytokine Expression in Human Endothelial and Epithelial Cells by Up-Regulating TLR3 Expression1 (2005) (167)
Retinoic acid activates interferon regulatory factor-1 gene expression in myeloid cells. (1996) (165)
Regulation of IFN-alpha/beta, MxA, 2',5'-oligoadenylate synthetase, and HLA gene expression in influenza A-infected human lung epithelial cells. (1997) (165)
Gene expression profiling during differentiation of human monocytes to macrophages or dendritic cells (2007) (163)
Activation of IFN-alpha, IFN-gamma, MxA, and IFN regulatory factor 1 genes in influenza A virus-infected human peripheral blood mononuclear cells. (1995) (163)
Control of IFN-inducible MxA gene expression in human cells. (1993) (157)
Pandemic H1N1 2009 Influenza A Virus Induces Weak Cytokine Responses in Human Macrophages and Dendritic Cells and Is Highly Sensitive to the Antiviral Actions of Interferons (2009) (157)
The effect of probiotics on respiratory infections and gastrointestinal symptoms during training in marathon runners. (2007) (153)
Tumor Necrosis Factor Alpha Enhances Influenza A Virus-Induced Expression of Antiviral Cytokines by Activating RIG-I Gene Expression (2006) (153)
Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells. (1999) (148)
Antigenic properties and diagnostic potential of puumala virus nucleocapsid protein expressed in insect cells (1996) (143)
IFN-αβ Released by Mycobacterium tuberculosis-Infected Human Dendritic Cells Induces the Expression of CXCL10: Selective Recruitment of NK and Activated T Cells 1 (2003) (143)
Regulation of Virus-Induced IL-12 and IL-23 Expression in Human Macrophages1 (2002) (139)
Quantitative Subcellular Proteome and Secretome Profiling of Influenza A Virus-Infected Human Primary Macrophages (2011) (138)
Arginine/Lysine-rich Structural Element Is Involved in Interferon-induced Nuclear Import of STATs* (2001) (137)
Influenza A and sendai viruses induce differential chemokine gene expression and transcription factor activation in human macrophages. (2000) (136)
Granulocyte‐macrophage colony‐stimulating factor (GM‐CSF)‐induced STAT5 activation and target‐gene expression during human monocyte/macrophage differentiation (2002) (128)
Human MxB Protein, an Interferon-α-inducible GTPase, Contains a Nuclear Targeting Signal and Is Localized in the Heterochromatin Region beneath the Nuclear Envelope* (1996) (126)
NF-{kappa}B is transported into the nucleus by importin {alpha}3 and importin {alpha}4. (2005) (124)
Immune complexes in serum and cerebrospinal fluid of multiple sclerosis patients and patients with other neurological diseases (1982) (123)
Distribution of catechol-O-methyltransferase enzyme in rat tissues. (1994) (122)
Impaired antiviral response in human hepatoma cells. (1999) (121)
Probiotic Leuconostoc mesenteroides ssp. cremoris and Streptococcus thermophilus induce IL-12 and IFN-gamma production. (2008) (119)
Interferon-induced Mx proteins form oligomers and contain a putative leucine zipper. (1992) (117)
Cytokine and contact-dependent activation of natural killer cells by influenza A or Sendai virus-infected macrophages. (2004) (116)
IFN‐α regulates Toll‐like receptor‐mediated IL‐27 gene expression in human macrophages (2007) (116)
Inhibition of human natural killer cell activity by cereulide, an emetic toxin from Bacillus cereus (2002) (115)
Inhibition of puumala and tula hantaviruses in Vero cells by MxA protein. (1996) (115)
Secretion and biological activities of heparin-binding growth-associated molecule. Neurite outgrowth-promoting and mitogenic actions of the recombinant and tissue-derived protein. (1992) (114)
Lactobacilli and streptococci induce inflammatory chemokine production in human macrophages that stimulates Th1 cell chemotaxis (2003) (113)
Lactobacilli and Streptococci activate NF-kappa B and STAT signaling pathways in human macrophages. (2000) (112)
Retinoic acid inducible gene-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines. (2006) (112)
The interferon-inducible RNA helicase, mda-5, is involved in measles virus-induced expression of antiviral cytokines. (2006) (109)
RIG-I-mediated Activation of p38 MAPK Is Essential for Viral Induction of Interferon and Activation of Dendritic Cells (2009) (108)
Differential Expression of IFN Regulatory Factor 4 Gene in Human Monocyte-Derived Dendritic Cells and Macrophages1 (2005) (107)
Proteome analysis reveals ubiquitin-conjugating enzymes to be a new family of interferon-alpha-regulated genes. (2000) (104)
Avian and 1918 Spanish Influenza A Virus NS1 Proteins Bind to Crk/CrkL Src Homology 3 Domains to Activate Host Cell Signaling* (2008) (103)
IFN-alpha and IL-18 synergistically enhance IFN-gamma production in human NK cells: differential regulation of Stat4 activation and IFN-gamma gene expression by IFN-alpha and IL-12. (2001) (103)
Expression of hepatitis C virus core protein inhibits interferon‐induced nuclear import of STATs (2004) (102)
N-glycosylation of human interferon-gamma: glycans at Asn-25 are critical for protease resistance. (1995) (101)
TNF-α and IFN-α enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells (2006) (99)
Induction of IRF-3 and IRF-7 phosphorylation following activation of the RIG-I pathway. (2006) (94)
The proximal interferon-stimulated response elements are essential for interferon responsiveness: a promoter analysis of the antiviral MxA gene. (1998) (92)
Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines: Implications for Pandemrix-Associated Narcolepsy Risk (2014) (91)
Retinoic acid induces signal transducer and activator of transcription (STAT) 1, STAT2, and p48 expression in myeloid leukemia cells and enhances their responsiveness to interferons. (1997) (90)
Virus infection induces proteolytic processing of IL‐18 in human macrophages via caspase‐1 and caspase‐3 activation (2001) (87)
IL‐21 enhances SOCS gene expression and inhibits LPS‐induced cytokine production in human monocyte‐derived dendritic cells (2006) (86)
NF-kappaB p52, RelB and c-Rel are transported into the nucleus via a subset of importin alpha molecules. (2008) (82)
Influenza A Virus-Induced IFN-α/β and IL-18 Synergistically Enhance IFN-γ Gene Expression in Human T Cells (1998) (82)
Role of N-glycosylation in the synthesis, dimerization and secretion of human interferon-gamma. (1994) (81)
Neutralizing antibodies reduce MxA protein induction in interferon- beta-1a-treated MS patients (2002) (81)
Obatoclax, Saliphenylhalamide, and Gemcitabine Inhibit Influenza A Virus Infection* (2012) (79)
Severe Acute Respiratory Syndrome Coronavirus Fails To Activate Cytokine-Mediated Innate Immune Responses in Cultured Human Monocyte-Derived Dendritic Cells (2005) (79)
Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/chemokine gene expression (2006) (78)
Potentially probiotic bacteria induce efficient maturation but differential cytokine production in human monocyte-derived dendritic cells. (2008) (76)
Persistence of anti-mumps virus antibodies after a two-dose MMR vaccination. A nine-year follow-up. (1995) (75)
Narcolepsy patients have antibodies that stain distinct cell populations in rat brain and influence sleep patterns (2014) (74)
Regulation of HLA class I and II expression by interferons and influenza A virus in human peripheral blood mononuclear cells (1997) (74)
Middle East respiratory syndrome coronavirus shows poor replication but significant induction of antiviral responses in human monocyte-derived macrophages and dendritic cells. (2016) (73)
Live Lactobacillus rhamnosus and Streptococcus pyogenes differentially regulate Toll‐like receptor (TLR) gene expression in human primary macrophages (2008) (72)
IFN-alpha beta released by Mycobacterium tuberculosis-infected human dendritic cells induces the expression of CXCL10: selective recruitment of NK and activated T cells. (2003) (72)
Minor Changes in the Hemagglutinin of Influenza A(H1N1)2009 Virus Alter Its Antigenic Properties (2011) (70)
Enzyme immunoassay, complement fixation and hemagglutination inhibition tests in the diagnosis of influenza A and B virus infections. Purified hemagglutinin in subtype-specific diagnosis. (1985) (70)
IFN-alpha regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages. (2007) (70)
Activation, cytokine production, and intracellular survival of bacteria in Salmonella‐infected human monocyte‐derived macrophages and dendritic cells (2005) (69)
Cellular immunity to mumps virus in young adults 21 years after measles-mumps-rubella vaccination. (2007) (67)
Lysosomal aspartylglucosaminidase is processed to the active subunit complex in the endoplasmic reticulum. (1993) (66)
Effect of probiotic Lactobacillus rhamnosus GG intervention on global serum lipidomic profiles in healthy adults. (2008) (66)
IFN‐α regulates IL‐21 and IL‐21R expression in human NK and T cells (2004) (65)
Expression of MxA Protein in Blood Lymphocytes Discriminates between Viral and Bacterial Infections in Febrile Children (1997) (62)
The NS1 Protein of Influenza A Virus Blocks RIG-I-Mediated Activation of the Noncanonical NF-κB Pathway and p52/RelB-Dependent Gene Expression in Lung Epithelial Cells (2012) (61)
Interferon-induced gene expression and signaling in human hepatoma cell lines. (2000) (60)
Novel activities of safe-in-human broad-spectrum antiviral agents (2018) (59)
Measles Virus Activates NF-κB and STAT Transcription Factors and Production of IFN-α/β and IL-6 in the Human Lung Epithelial Cell Line A549 (2001) (58)
Interaction of viral envelope glycoproteins with fibronectin (1983) (57)
IFN-α and IL-12 activate IFN regulatory factor 1 (IRF-1), IRF-4, and IRF-8 gene expression in human NK and T cells (2003) (56)
Effect of interferon-alpha and cell differentiation on Puumala virus infection in human monocyte/macrophages. (1995) (56)
Incoming Influenza A Virus Evades Early Host Recognition, while Influenza B Virus Induces Interferon Expression Directly upon Entry (2012) (55)
Multiple NF-κB and IFN Regulatory Factor Family Transcription Factors Regulate CCL19 Gene Expression in Human Monocyte-Derived Dendritic Cells1 (2007) (54)
Mass spectrometric characterization of glycosylated interferon‐γ variants separated by gel electrophoresis (1996) (54)
Involvement of TBK1 and IKKϵ in lipopolysaccharide‐induced activation of the interferon response in primary human macrophages (2007) (54)
TLR ligands induce synergistic interferon-β and interferon-λ1 gene expression in human monocyte-derived dendritic cells. (2011) (54)
Phospholipid transfer is a prerequisite for PLTP-mediated HDL conversion. (2000) (54)
Genetic Diversity of the 2009 Pandemic Influenza A(H1N1) Viruses in Finland (2010) (53)
No Serological Evidence of Influenza A H1N1pdm09 Virus Infection as a Contributing Factor in Childhood Narcolepsy after Pandemrix Vaccination Campaign in Finland (2013) (53)
Expression of recombinant soluble and membrane-bound catechol O-methyltransferase in eukaryotic cells and identification of the respective enzymes in rat brain. (1992) (53)
Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIG-I signaling (2015) (53)
Nonpathogenic Lactobacillus rhamnosus activates the inflammasome and antiviral responses in human macrophages (2012) (49)
Lactobacillus rhamnosus GG and Streptococcus thermophilus induce suppressor of cytokine signalling 3 (SOCS3) gene expression directly and indirectly via interleukin‐10 in human primary macrophages (2011) (49)
Innate Immune Responses in Human Monocyte-Derived Dendritic Cells Are Highly Dependent on the Size and the 5′ Phosphorylation of RNA Molecules (2011) (48)
Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin (2012) (47)
TNF-alpha and IFN-alpha enhance influenza-A-virus-induced chemokine gene expression in human A549 lung epithelial cells. (2006) (47)
Effect of carbohydrates on the pharmacokinetics of human interferon-gamma. (1993) (47)
Hepatitis C virus core, NS3, NS4B and NS5A are the major immunogenic proteins in humoral immunity in chronic HCV infection (2009) (47)
Mutational analysis of murine Mx1 protein: GTP binding core domain is essential for anti-influenza A activity. (1994) (45)
Blood MxA protein as a marker for respiratory virus infections in young children (2014) (45)
Rapid diagnosis of respiratory adenovirus infections in young adult men (1986) (45)
Hepatitis C virus NS2 protease inhibits host cell antiviral response by inhibiting IKKε and TBK1 functions (2013) (45)
Nuclear Cotransport Mechanism of Cytoplasmic Human MxB Protein* (1997) (45)
Regulation of IRF and STAT gene expression by retinoic acid. (1998) (45)
Narcolepsy Associated with Pandemrix Vaccine (2018) (45)
Cytokine responses in cord blood predict the severity of later respiratory syncytial virus infection. (2009) (43)
Anticancer compound ABT-263 accelerates apoptosis in virus-infected cells and imbalances cytokine production and lowers survival rates of infected mice (2013) (43)
Critical immunological pathways are downregulated in APECED patient dendritic cells (2008) (43)
Does matrix-assisted laser desorption/ionization mass spectrometry allow analysis of carbohydrate heterogeneity in glycoproteins? A study of natural human interferon-gamma. (1996) (41)
Antiviral Properties of Chemical Inhibitors of Cellular Anti-Apoptotic Bcl-2 Proteins (2017) (40)
Efficacy of PCR and other diagnostic methods for the detection of respiratory adenoviral infections (1999) (38)
Cells of the Neuronal Lineage Play a Major Role in the Generation of Amyloid Precursor Fragments in Gelsolin-related Amyloidosis* (1998) (38)
Chondroitin sulfate at the plasma membranes of cultured fibroblasts (1983) (38)
Immunoglobulin G subclass antibody responses in influenza A and parainfluenza type 1 virus infections. (1985) (38)
Akt Inhibitor MK2206 Prevents Influenza pH1N1 Virus Infection In Vitro (2014) (37)
Prospective clinical and serological follow-up in early childhood reveals a high rate of subclinical RSV infection and a relatively high reinfection rate within the first 3 years of life (2016) (36)
Inhibition of Human NK Cell Function by Valinomycin, a Toxin from Streptomyces griseus in Indoor Air (2000) (35)
Streptococcus pyogenes activates human plasmacytoid and myeloid dendritic cells (2007) (35)
Analysis of Influenza B Virus NS1 Protein Trafficking Reveals a Novel Interaction with Nuclear Speckle Domains (2008) (35)
Enzymatic characterization of interferon-induced antiviral GTPases murine Mx1 and human MxA proteins. (1994) (35)
Biosynthesis and N-glycosylation of human interferon-gamma. Asn25 and Asn97 differ markedly in how efficiently they are glycosylated and in their oligosaccharide composition. (1996) (34)
Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells. (2007) (33)
Inhibition of dynamin‐dependent endocytosis interferes with type III IFN expression in bacteria‐infected human monocyte‐derived DCs (2010) (33)
Activation of pro-matrix metalloproteinase-9 and degradation of gelatin by the surface protease PgtE of Salmonella enterica serovar Typhimurium. (2008) (33)
Proportions of Ig Classes and Subclasses in Mumps Antibodies (1985) (33)
Efficacy of PCR and other diagnostic methods for the detection of respiratory adenoviral infections. (1999) (32)
IFN-alpha regulates IL-21 and IL-21R expression in human NK and T cells. (2004) (32)
Regulation of kynurenine biosynthesis during influenza virus infection (2017) (32)
Spectrally and Spatially Multiplexed Serological Array-in-Well Assay Utilizing Two-Color Upconversion Luminescence Imaging. (2016) (32)
Elevated serum immune complex levels in Pogosta disease, an acute alphavirus infection with rash and arthritis. (1986) (31)
Oncogenic Herpesvirus Utilizes Stress-Induced Cell Cycle Checkpoints for Efficient Lytic Replication (2016) (31)
Hepatitis C virus proteins interfere with the activation of chemokine gene promoters and downregulate chemokine gene expression. (2008) (31)
Sudden Deafness: Lack of Evidence for Systemic Viral Infection (1998) (31)
The monopartite nuclear localization signal of autoimmune regulator mediates its nuclear import and interaction with multiple importin α molecules (2006) (31)
CHRONIC ENCEPHALOMYELITIS WITH SPECIFIC INCREASE IN INTRATHECAL MUMPS ANTIBODIES (1982) (30)
Viral antibodies and interferon in acute psychiatric disorders. (1987) (30)
RIG-I Signaling Is Essential for Influenza B Virus-Induced Rapid Interferon Gene Expression (2015) (29)
Comparative analysis of COVID-19 vaccine responses and third booster dose-induced neutralizing antibodies against Delta and Omicron variants (2022) (29)
Serological diagnosis of influenza A and B infections by enzyme immunoassay. Comparison with the complement fixation test. (1984) (29)
Effectiveness of Pandemic and Seasonal Influenza Vaccines in Preventing Laboratory-Confirmed Influenza in Adults: A Clinical Cohort Study during Epidemic Seasons 2009–2010 and 2010–2011 in Finland (2014) (29)
IFN-alpha and IL-12 activate IFN regulatory factor 1 (IRF-1), IRF-4, and IRF-8 gene expression in human NK and T cells. (2003) (28)
Measles virus activates NF-kappa B and STAT transcription factors and production of IFN-alpha/beta and IL-6 in the human lung epithelial cell line A549. (2001) (27)
Influenza virus NS1 protein binds cellular DNA to block transcription of antiviral genes. (2016) (26)
Transcript profiles of dendritic cells of PLOSL patients link demyelinating CNS disorders with abnormalities in pathways of actin bundling and immune response (2007) (26)
Expression of HCV structural proteins impairs IFN-mediated antiviral response. (2002) (26)
Primary Folding of Aspartylglucosaminidase (1996) (25)
Interferons Induce STAT1-Dependent Expression of Tissue Plasminogen Activator, a Pathogenicity Factor in Puumala Hantavirus Disease. (2016) (23)
Etiology of central nervous system infections in the Philippines and the role of serum C-reactive protein in excluding acute bacterial meningitis. (1998) (23)
Type I interferon response against viral and non‐viral gene transfer in human tumor and primary cell lines (2007) (23)
Validation and Diagnostic Application of NS and HA Gene-Specific Real-Time Reverse Transcription-PCR Assays for Detection of 2009 Pandemic Influenza A (H1N1) Viruses in Clinical Specimens (2011) (22)
Chronic mumps virus encephalitis Mumps antibody levels in cerebrospinal fluid (1985) (22)
Interferon-alpha inhibits Stat5 DNA-binding in IL-2 stimulated primary T-lymphocytes. (2002) (22)
MAP kinase p38α regulates type III interferon (IFN‐λ1) gene expression in human monocyte‐derived dendritic cells in response to RNA stimulation (2015) (21)
Zika Virus Non-Structural Protein NS5 Inhibits the RIG-I Pathway and Interferon Lambda 1 Promoter Activation by Targeting IKK Epsilon (2019) (21)
Treatment of lymphatic malformations of head and neck with OK-432 sclerotherapy induce systemic inflammatory response (2010) (21)
Ebolavirus protein VP24 interferes with innate immune responses by inhibiting interferon-λ1 gene expression. (2017) (21)
A Combination of N and S Antigens With IgA and IgG Measurement Strengthens the Accuracy of SARS-CoV-2 Serodiagnostics (2021) (21)
Does autoreactivity have a role in narcolepsy? (2014) (19)
Parental influenza virion nucleocapsids are efficiently transported into the nuclei of murine cells expressing the nuclear interferon-induced Mx protein (1990) (18)
Surveillance of influenza in Finland during the 2009 pandemic, 10 May 2009 to 8 March 2010. (2011) (18)
Long-Lasting T Cell Responses in BNT162b2 COVID-19 mRNA Vaccinees and COVID-19 Convalescent Patients (2022) (17)
Human kinome analysis reveals novel kinases contributing to virus infection and retinoic-acid inducible gene I-induced type I and type III IFN gene expression (2013) (16)
Circulating immune complexes in Yersinia infection. (1984) (16)
Differential inactivation of interferons by a protease from human granulocytes. (1992) (16)
Production, purification and immunogenicity of recombinant Ebola virus proteins - A comparison of Freund's adjuvant and adjuvant system 03. (2017) (16)
Reduced cross-protection against influenza A(H3N2) subgroup 3C.2a and 3C.3a viruses among Finnish healthcare workers vaccinated with 2013/14 seasonal influenza vaccine. (2015) (16)
Highly Pathogenic H5N1 Influenza A Virus Spreads Efficiently in Human Primary Monocyte-Derived Macrophages and Dendritic Cells (2018) (16)
COVID-19 mRNA vaccine induced antibody responses and neutralizing antibodies against three SARS-CoV-2 variants (2021) (16)
Interleukin-5, interleukin-6, interferon induced protein-10, procalcitonin and C-reactive protein among mechanically ventilated severe community-acquired viral and bacterial pneumonia patients (2018) (15)
Immuno-modulating properties of saliphenylhalamide, SNS-032, obatoclax, and gemcitabine. (2016) (15)
Novel Avian Influenza A (H7N9) Virus Induces Impaired Interferon Responses in Human Dendritic Cells (2014) (15)
Immunoglobulin class-specific serological responses to adenovirus in respiratory infections of young adult men (1986) (15)
Influenza virus infections from 0 to 2 years of age: A birth cohort study. (2017) (14)
Full-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Finnish Patients from 2009 to 2013 (2014) (14)
Measles virus enhances the expression of cellular immediate-early genes and DNA-binding of transcription factor AP-1 in lung epithelial A549 cells (2002) (14)
Activation of IFN-alpha, IFN-gamma, MxA and IRF-1 genes on influenza A virus-infected human peripheral blood mononuclear cells (1995) (14)
Detection of rotavirus in faecal specimens by enzyme immunoassay, latex agglutination and electron microscopy. (1985) (14)
Localization of viral-envelope-glycoprotein-binding sites in fibronectin. (1984) (13)
A highly sensitive and specific SARS-CoV-2 spike- and nucleoprotein-based fluorescent multiplex immunoassay (FMIA) to measure IgG, IgA and IgM class antibodies (2021) (12)
Probiotics and respiratory and gastrointestinal tract infections in Finnish military conscripts - a randomised placebo-controlled double-blinded study. (2016) (12)
Asian and African lineage Zika viruses show differential replication and innate immune responses in human dendritic cells and macrophages (2019) (12)
Serological Array-in-Well Multiplex Assay Reveals a High Rate of Respiratory Virus Infections and Reinfections in Young Children (2019) (12)
Fibronectin and viral pathogenesis. (1987) (12)
Lack of Induction by Rhinoviruses of Systemic Type I Interferon Production or Enhanced MxA Protein Expression During the Common Cold (1999) (12)
Dynamin inhibition interferes with inflammasome activation and cytokine gene expression in Streptococcus pyogenes‐infected human macrophages (2014) (11)
Antibody responses to mumps virus proteins in natural mumps infection and after vaccination with live and inactivated mumps virus vaccines (1984) (11)
Interferon regulatory factor (IRF) family members differentially regulate the expression of type III interferon (IFN-lambda) genes (2007) (10)
Sudden Deafness and Viral Infections (2000) (10)
Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication (2014) (10)
Primary Folding of Aspartylglucosaminidase SIGNIFICANCE OF DISULFIDE BRIDGES AND EVIDENCE OF EARLY MULTIMERIZATION* (1996) (9)
SARS-CoV-2 Isolates Show Impaired Replication in Human Immune Cells but Differential Ability to Replicate and Induce Innate Immunity in Lung Epithelial Cells (2021) (9)
Antibody responses against influenza A(H1N1)pdm09 virus after sequential vaccination with pandemic and seasonal influenza vaccines in Finnish healthcare professionals (2012) (9)
Immune complex assays and stored normal human sera. (1983) (9)
Neuroimmunology: Disease mechanisms in narcolepsy remain elusive (2014) (9)
Efficient replication and strong induction of innate immune responses by H9N2 avian influenza virus in human dendritic cells. (2014) (9)
Preparation of nasopharyngeal secretions for immunofluorescence by one-step centrifugation through Percoll. (1987) (9)
Sensitive interferon assay based on immunoenzymatic quantification of viral antigen synthesis. (1982) (8)
Efficient Inhibition of Avian and Seasonal Influenza A Viruses by a Virus-Specific Dicer-Substrate Small Interfering RNA Swarm in Human Monocyte-Derived Macrophages and Dendritic Cells (2018) (8)
COVID-19 adenovirus vaccine triggers antibodies against PF4 complexes to activate complement and platelets (2021) (8)
[Narcolepsy as an autoimmune disease]. (2015) (8)
Comparative Analysis of Whole-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Hospitalized and Nonhospitalized Patients Identifies Missense Mutations That Might Be Associated with Patient Hospital Admissions in Finland during 2009 to 2014 (2015) (8)
TNF-alpha and IFN-alpha pretreatment enhances influenza A virus-induced chemokine gene expression in lung epithelial cells (2006) (7)
Potentially probiotic bacteria induce cytokine production and suppressor of cytokine signaling 3 gene expression in human monocyte-derived macrophages (2009) (7)
The NS 1 Protein of Influenza A Virus Blocks RIGI-Mediated Activation of the Noncanonical NF-B Pathway and p 52 / RelB-Dependent Gene Expression in Lung Epithelial Cells (2012) (7)
and T Cells Production in Human NK γ Enhances IFN- IL-21 in Synergy with IL-15 or IL-18 (2013) (6)
Arginine/lysine-rich NLS mediates interactions between dimeric STATs and importin 5 (2002) (6)
Pandemic influenza A(H1N1pdm09) vaccine induced high levels of influenza-specific IgG and IgM antibodies as analyzed by enzyme immunoassay and dual-mode multiplex microarray immunoassay methods. (2020) (6)
Serum antibodies to putative proteinase maturation protein A in children with acute otitis media. (2006) (5)
369 NF-κB is transported into the nucleus via a subset of importin α molecules (2008) (5)
Does matrix-assisted laser desorption/ionization mass spectrometry allow analysis of carbohydarte heterogeneity in glycoproteins? (1996) (5)
RIG-I and mda-5 are involved in influenza A virus-induced expression of antiviral cytokines (2006) (5)
EXPRESSION OF MxA PROTEIN IN BLOOD LYMPHOCYTES OF CHILDREN RECEIVING ANTICANCER CHEMOTHERAPY (2006) (5)
Filovirus VP24 Proteins Differentially Regulate RIG-I and MDA5-Dependent Type I and III Interferon Promoter Activation (2022) (4)
Structural and functional analysis reveals that human OASL binds dsRNA to enhance RIGI signaling (2015) (4)
Nuclear Translocation of Crk Adaptor Proteins by the Influenza A Virus NS1 Protein (2016) (4)
Low pre-vaccination SARS-CoV-2 seroprevalence in Finnish health care workers: a prospective cohort study (2022) (4)
Vaccine-Induced Antibody Responses against SARS-CoV-2 Variants-Of-Concern Six Months after the BNT162b2 COVID-19 mRNA Vaccination (2022) (4)
A Highly Sensitive and Specific SARS-CoV-2 Spike- and Nucleoprotein-Based Fluorescent Multiplex Immunoassay (FMIA) to Measure IgG, IgA, and IgM Class Antibodies (2021) (4)
Elevated mumps antibody titers in the cerebrospinal fluid suggesting chronic mumps virus infection in the central nervous system. (1985) (4)
Comparison of culture, enzyme immunoassay and nucleic acid sandwich hybridization in detecting Chlamydia trachomatis in genital tract infections (1988) (4)
In vitro production of synthetic viral RNAs and their delivery into mammalian cells and the application of viral RNAs in the study of innate interferon responses. (2020) (3)
Human Influenza A Viruses (2020) (3)
C3b binding and IgG binding onto platelets in hepatitis B virus infection. (1980) (3)
Long-lasting heterologous antibody responses after sequential vaccination with A/Indonesia/5/2005 and A/Vietnam/1203/2004 pre-pandemic influenza A(H5N1) virus vaccines. (2020) (3)
The effect of probiotics on respiratory infections and gastrointestinal symptom episodes during the marathon training period in marathon runners (2007) (3)
Serological Follow-Up Study Indicates High Seasonal Coronavirus Infection and Reinfection Rates in Early Childhood (2022) (3)
No evidence of autoimmunity to human OX1 or OX2 orexin receptors in Pandemrix-vaccinated narcoleptic children (2020) (3)
Complete Genome Sequences of Influenza A/H1N1 Strains Isolated from Patients during the 2013-2014 Epidemic Season in Finland (2015) (3)
Strong Neutralizing Antibody Responses to SARS-CoV-2 Variants Following a Single Vaccine Dose in Subjects With Previous SARS-CoV-2 Infection (2022) (2)
Immunity Development of Interferon Antiviral Role of Viral Ribonucleoprotein in the Vesicular Stomatitis Virus Infection and the Kinases by ε Activation of TBK 1 and IKK (2004) (2)
Cellular and humoral immunity to mumps virus in young adults 21 years after MMR vaccination (2007) (2)
Mental retardation associated with elevated cerebrospinal fluid antibody levels to herpes simplex, adeno and mumps viruses. (1987) (2)
SARS-CoV-2 variants Alpha, Beta, Delta and Omicron show a slower host cell interferon response compared to an early pandemic variant (2022) (2)
Seasonal influenza vaccines induced high levels of neutralizing cross-reactive antibody responses against different genetic group influenza A(H1N1)pdm09 viruses. (2019) (2)
[Influenza viruses--a challenge for vaccinations]. (2012) (2)
Expression in Human Macrophages Regulation of Virus-Induced IL-12 and IL-23 (2013) (1)
Serum immune complexes and rheumatoid factors in superficial bladder tumours. (1987) (1)
P4: Epidemiology of hepatitis C virus infections in Finland between the years 1995 and 2011 (2013) (1)
Comparison of Zaire ebolavirus realtime RT-PCRs targeting the nucleoprotein gene. (2020) (1)
Comparative analysis of BNT162b2, mRNA-1273 and ChAdOx1 COVID-19 vaccine induced antibody responses and the 3rd BNT162b2 vaccine induced neutralizing antibodies against Delta and Omicron variants (2022) (1)
Inactivation efficacy of H5N1 avian influenza virus by commonly used sample preparation reagents for safe laboratory practices. (2022) (1)
Methods for Detecting Antimeasles, Mumps, and Rubella Virus Antibodies (1998) (1)
Middle East respiratory syndrome coronavirus (MERS-CoV) shows poor replication and weak induction of antiviral responses in human monocyte-derived macrophages and dendritic cells (2015) (1)
Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication (2014) (1)
TNF-alpha enhances influenza A virus-induced expression of antiviral cytokines by activating RIG-I gene expression (2006) (1)
Negative regulation of the RIG-I induced antiviral state by the ubiquitin editing protein A20 (2006) (1)
Proportions of immunoglobulin isotypes in paralytic poliomyelitis and after vaccination (1987) (1)
Interaction of Ebola Virus with the Innate Immune System (2019) (1)
Influenza A H3N2 subtype virus NS1 protein targets into the nucleus and binds primarily via its C-terminal NLS2/NoLS to nucleolin and fibrillarin (2012) (1)
Inhibition of dynamin-dependent endocytosis interferes with type III IFN expression in bacteria-infected human dendritic cells (2009) (1)
Expression of catechol-O-methyltransferase (COMT) in rat brain and peripheral tissues (1992) (1)
Expression and Epithelial Cells by Up-Regulating TLR 3 Cytokine Expression in Human Endothelial Enhances TLR 3-Mediated Antiviral α IFN-Sampsa (2005) (1)
C3c-binding in inflammatory rheumatic diseases. (1984) (1)
Regulation of IL-12 and IL-23 gene expression in viral infections (2002) (0)
Transcript profiles of monocyte-derived dendritic cells of PLOSL patients with Dap12 and Trem2 mutations (2007) (0)
253 Hepatitis C virus NS3/4A protein downregulates toll-like receptor 7 signalling pathway (2008) (0)
Jaana Blood Mononuclear Cells Interferon Production in Human Peripheral Interleukin-12 ( IL-12 ) , IL-18 , and Gamma Lactobacilli and Streptococci Induce (1998) (0)
NF-{kappa}B is transported into the nucleus by a subset of importin {alpha} molecules (2007) (0)
RapidDiagnosis ofRespiratory Adenovirus Infections in YoungAdultMen (1986) (0)
IFN-α and IL-12 differentially regulate IFN-γ gene expression in human NK and T cells (2000) (0)
IFN-alpha regulates virus infection-induced and Toll-like receptor-mediated IL-23 and IL-27 gene expression in human macrophages (2007) (0)
Nuclear and Nucleolar Targeting of Inﬂuenza A Virus NS1 Protein: Striking Differences between Different Virus Subtypes (cid:1) (2007) (0)
IFN- Released byMycobacterium tuberculosis-Infected Human Dendritic Cells Induces the Expression of CXCL10: Selective Recruitment of NK and Activated T Cells (2003) (0)
Infectious viruses from transfected SARS-CoV-2 genomic RNA (2023) (0)
313 Induction of IFN responses in influenza B virus-infected human monocyte-derived dendritic cells (2008) (0)
Toll-like receptor ligand-induced synergistic interferon gene expression in human monocyte-derived dendritic cells (2009) (0)
ID: 97: Novel RNA protection strategy against influenza A virus (2015) (0)
ID: 71: Ebola and Marburg virus proteins effectively interfere with the activation of TLR and RIG-I signaling pathways (2015) (0)
Impaired interferon production by leukocytes from patients with Bell palsy and lack of findings suggestive for a systemic viral involvement. (1997) (0)
Hepatitis C virus NS3/4A protein decreases interferon-alfa production in Hek293 cells (2009) (0)
Interferonâalpha inhibits Stat5 DNAâbinding in ILâ2 stimulated primary Tâlymphocytes (2002) (0)
Probiotic bacteria can induce the maturation and cytokine gene expression in human monocyte-derived dendritic cells (2007) (0)
Novel activities of safe-inhuman broad-spectrum antiviral agents Running title : Towards broad-spectrum antiviral drugs (2018) (0)
The crystal structure of the OAS-like domain (OLD) of human OASL (2015) (0)
Dimeric STATs interact with armadillo repeats 8 and 9 of human importin 5 (2003) (0)
The Regulation of CCL19 Gene Expression in Human Antigen Presenting Cells (B49) (2007) (0)
Persistent T cell-mediated immune responses against Omicron variants after the third COVID-19 mRNA vaccine dose (2023) (0)
Dendritic Cells and Macrophages Factor 4 Gene in Human Monocyte-Derived Differential Expression of IFN Regulatory (2005) (0)
Kinetics ofcytokine andNFATgeneexpression inhumaninterleukin-2-de pendent Tlymphoblasts stimulated viaT-cell receptor (1998) (0)
Expression in Human NK and T Cells and IL-12 Induce IL-18 Receptor Gene α IFN- (2013) (0)
157 : Dynamin inhibition interferes with cytokine responses in streptococcus pyogenes-infected human macrophages (2013) (0)
6: Innate immune responses in human dendritic cells induced by H9N2 avian influenza virus (2013) (0)
97. Type I Interferon Response Against Virus Vectors and Non-Viral Gene Transfer (2005) (0)
Lactic acid bacteria, which have pro-inflammatory properties (2007) (0)
Childhood narcolepsy in Finland before and after the 2009-2010 H1N1 pandemic vaccination campaign (2012) (0)
NF-κB is transported into the nucleus by a subset of importin α molecules (B51) (2007) (0)
177 Multiple intracellular signaling pathways contribute to synergistic TLR ligand-induced cytokine gene expression in human monocyte-derived dendritic cells (2008) (0)
Expression of Ebola and Marburg virus proteins and their effect on activation of innate interferon responses (2015) (0)
Zika virus NS5 protein interferes with the RIG-I signaling pathway and inhibits the expression of interferon lambda1 gene (2017) (0)
Streptococci and lactobacilli differentially induce maturation and production of cytokines and chemokines in human monocyte-derived dendritic cells (2004) (0)
Ef fi cient replication and strong induction of innate immune responses by H 9 N 2 avian in fl uenza virus in human dendritic cells (2014) (0)
ID: 98: H5N1 and H7N9 viruses induce impaired antiviral state in human immune cells by different mechanisms (2015) (0)
Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines Vaarala, Outi (0)
Experimental Studies on the Immunopathogenesis of Narcolepsy/Cataplexy in HLA-DQB1*0602 Transgenic NOD Mice (2013) (0)
Expression of type III lambda interferon genes is showing similar two-wave regulation with type I alpha/beta interferon genes (B50) (2007) (0)
Expression of structural proteins of HCV impairs IFN-alpha-mediated antiviral response (2002) (0)
191: Difference in the activation of IFN gene expression in response to influenza A and B virus entry (2013) (0)
[Chronic encephalitis caused by mumps virus]. (1986) (0)
ID: 28: Influenza B virus entry induces RIG-I-dependent rapid interferon gene expression (2015) (0)
COVID-19 adenovirus vector vaccine induces higher interferon and pro-inflammatory responses than mRNA vaccines in human PBMCs, macrophages and moDCs (2023) (0)
374 Tick-borne encephalitis virus proteins PRM and NS1 act as potent inhibitors of cytokine gene expression (2008) (0)
314 The role of type I and type III interferons in Salmonella-infected dendritic cells (2008) (0)
Comparison of different Zaire ebolavirus realtime RT-PCRs targeting the nucleoprotein gene (2020) (0)

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