Junichi Takagi

Q: What Schools Are Affiliated With Junichi Takagi

Junichi Takagi is affiliated with the following schools: University of Tokyo, Institute of Science Tokyo, Osaka University, Kyoto University, Harvard University

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Junichi Takagi

Computer Science

#9604

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#10080

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Machine Learning

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#4298

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Artificial Intelligence

#4600

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#4662

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#6573

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#6808

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Computer Science

Junichi Takagi's Degrees

PhD Computer Science University of Tokyo
Masters Computer Science University of Tokyo
Bachelors Computer Science University of Tokyo

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Junichi Takagi's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Global Conformational Rearrangements in Integrin Extracellular Domains in Outside-In and Inside-Out Signaling (2002) (1159)
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics (2004) (829)
Conformational regulation of integrin structure and function. (2002) (552)
Structures of the αL I Domain and Its Complex with ICAM-1 Reveal a Shape-Shifting Pathway for Integrin Regulation (2003) (509)
Integrin activation and structural rearrangement (2002) (400)
Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression. (2018) (345)
Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation (2002) (327)
Structure of integrin α5β1 in complex with fibronectin (2003) (305)
Ligand-binding specificities of laminin-binding integrins: A comprehensive survey of laminin–integrin interactions using recombinant α3β1, α6β1, α7β1 and α6β4 integrins (2006) (298)
Semaphorin 7A initiates T-cell-mediated inflammatory responses through α1β1 integrin (2007) (251)
C-terminal opening mimics 'inside-out' activation of integrin α5β1 (2001) (227)
Crystal structure of autotaxin and insight into GPCR activation by lipid mediators (2011) (227)
Reversibly locking a protein fold in an active conformation with a disulfide bond: Integrin αL I domains with high affinity and antagonist activity in vivo (2001) (224)
Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair (2001) (217)
A Specific Interface between Integrin Transmembrane Helices and Affinity for Ligand (2004) (211)
The RGD motif in fibronectin is essential for development but dispensable for fibril assembly (2007) (208)
Locking in alternate conformations of the integrin αLβ2 I domain with disulfide bonds reveals functional relationships among integrin domains (2001) (199)
Crystal structure of α5β1 integrin ectodomain: Atomic details of the fibronectin receptor (2012) (197)
Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin. (2007) (181)
Ligand-binding specificities of laminin-binding integrins: a comprehensive survey of laminin-integrin interactions using recombinant alpha3beta1, alpha6beta1, alpha7beta1 and alpha6beta4 integrins. (2006) (170)
Disrupting integrin transmembrane domain heterodimerization increases ligand binding affinity, not valency or clustering. (2005) (165)
Structural basis for ligand recognition by RGD (Arg-Gly-Asp)-dependent integrins. (2004) (156)
Crystal structures of the noncatalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor (2009) (155)
Stabilizing the open conformation of the integrin headpiece with a glycan wedge increases affinity for ligand (2003) (151)
Potentiation of the ligand-binding activity of integrin α3β1 via association with tetraspanin CD151 (2005) (150)
Structural basis for semaphorin signalling through the plexin receptor (2010) (149)
Computational design of an integrin I domain stabilized in the open high affinity conformation (2000) (147)
PA tag: a versatile protein tagging system using a super high affinity antibody against a dodecapeptide derived from human podoplanin. (2014) (146)
An isolated, surface-expressed I domain of the integrin αLβ2 is sufficient for strong adhesive function when locked in the open conformation with a disulfide bond (2001) (145)
Lysosomal Sorting of Amyloid-β by the SORLA Receptor Is Impaired by a Familial Alzheimer’s Disease Mutation (2014) (132)
Complex between nidogen and laminin fragments reveals a paradigmatic β-propeller interface (2003) (128)
Changing Ligand Specificities of αvβ1 and αvβ3 Integrins by Swapping a Short Diverse Sequence of the β Subunit* (1997) (121)
Structural basis for ligand recognition by integrins. (2007) (120)
Archaeal Surface Layer Proteins Contain β Propeller, PKD, and β Helix Domains and Are Related to Metazoan Cell Surface Proteins (2002) (118)
Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin (2016) (116)
Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling (2012) (108)
Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c (2016) (106)
Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors (2017) (105)
Intersubunit signal transmission in integrins by a receptor-like interaction with a pull spring. (2004) (102)
Structural and functional studies with antibodies to the integrin beta 2 subunit. A model for the I-like domain. (2000) (100)
Locking the β3 Integrin I-like Domain into High and Low Affinity Conformations with Disulfides* (2004) (97)
Milk fat globule EGF factor 8 in the serum of human patients of systemic lupus erythematosus (2008) (94)
The activated conformation of integrin β7 is a novel multiple myeloma–specific target for CAR T cell therapy (2017) (89)
Allosteric β1 Integrin Antibodies That Stabilize the Low Affinity State by Preventing the Swing-out of the Hybrid Domain* (2004) (82)
Potentiation of the ligand-binding activity of integrin alpha3beta1 via association with tetraspanin CD151. (2005) (81)
Two-stage Activation for α5β1Integrin Binding to Surface-adsorbed Fibronectin* (1998) (80)
C-terminal opening mimics 'inside-out' activation of integrin alpha5beta1. (2001) (79)
12S-hydroxyeicosatetraenoic acid plays a central role in the regulation of platelet activation. (1991) (79)
Dimerization and the effectiveness of ICAM-1 in mediating LFA-1-dependent adhesion (2001) (76)
Structural basis for perception of diverse chemical substances by T1r taste receptors (2017) (73)
Structural basis for specific recognition of reelin by its receptors. (2010) (71)
Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors (2007) (71)
Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization (2018) (71)
Stabilizing the integrin αM inserted domain in alternative conformations with a range of engineered disulfide bonds (2002) (70)
Redox-assisted regulation of Ca2+ homeostasis in the endoplasmic reticulum by disulfide reductase ERdj5 (2016) (69)
Crystal structure of a mammalian Wnt–frizzled complex (2019) (69)
Archaeal surface layer proteins contain beta propeller, PKD, and beta helix domains and are related to metazoan cell surface proteins. (2002) (68)
Tissue Transglutaminase, Coagulation Factor XIII, and the Pro-polypeptide of von Willebrand Factor Are All Ligands for the Integrins α9β1 and α4β1 * (2000) (67)
Integrin beta3 regions controlling binding of murine mAb 7E3: implications for the mechanism of integrin alphaIIbbeta3 activation. (2004) (67)
Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin β subunits (2001) (67)
Engineered ACE2 receptor therapy overcomes mutational escape of SARS-CoV-2 (2021) (66)
Dual functions of transglutaminase in novel cell adhesion. (1996) (63)
The role of the specificity-determining loop of the integrin beta subunit I-like domain in autonomous expression, association with the alpha subunit, and ligand binding. (2002) (63)
alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity. (2007) (63)
Allosteric Inhibition of a Semaphorin 4D Receptor Plexin B1 by a High-Affinity Macrocyclic Peptide. (2016) (60)
[Complex between nidogen and laminin fragments reveals a paradigmatic beta-propeller interface]. (2003) (57)
Modification of transglutaminase assay: use of ammonium sulfate to stop the reaction. (1986) (57)
Molecular Basis of the Recognition of Nephronectin by Integrin α8β1* (2009) (55)
Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V (2018) (53)
Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin αvβ3 induces signal transduction and enhances plasminogen activation (2006) (52)
Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state (2016) (51)
The Relative Influence of Metal Ion Binding Sites in the I-like Domain and the Interface with the Hybrid Domain on Rolling and Firm Adhesion by Integrin α4β7* (2004) (51)
The thioesterase domain from a nonribosomal peptide synthetase as a cyclization catalyst for integrin binding peptides (2002) (51)
Structural basis for amyloidogenic peptide recognition by sorLA (2015) (50)
Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase (2016) (50)
Higher-order architecture of cell adhesion mediated by polymorphic synaptic adhesion molecules neurexin and neuroligin. (2012) (49)
Platelet factor XIII. The collagen receptor? (1986) (48)
Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1. (2017) (48)
Macrocyclic peptide-based inhibition and imaging of hepatocyte growth factor (2019) (48)
Schwann cell myelination requires integration of laminin activities (2012) (46)
Interplay of Endosomal pH and Ligand Occupancy in Integrin α5β1 Ubiquitination, Endocytic Sorting, and Cell Migration. (2015) (45)
A collagen/gelatin-binding decapeptide derived from bovine propolypeptide of von Willebrand factor. (1992) (45)
Fibronectin peptides derived from two distinct regions stimulate adipocyte differentiation by preventing fibronectin matrix assembly. (2002) (43)
The unique prodomain of T-cadherin plays a key role in adiponectin binding with the essential extracellular cadherin repeats 1 and 2 (2017) (42)
Activity-independent cell adhesion to tissue-type transglutaminase is mediated by α4β1 integrin (1999) (41)
Two-stage activation for alpha5beta1 integrin binding to surface-adsorbed fibronectin. (1998) (39)
Structure of a signaling‐competent reelin fragment revealed by X‐ray crystallography and electron tomography (2006) (37)
The Top of the Inserted-like Domain of the Integrin Lymphocyte Function-associated Antigen-1 β Subunit Contacts the α Subunit β-Propeller Domain near β-Sheet 3* (2000) (37)
Tissue transglutaminase, coagulation factor XIII, and the pro-polypeptide of von Willebrand factor are all ligands for the integrins alpha 9beta 1 and alpha 4beta 1. (2000) (36)
Classification of ‘activation’ antibodies against integrin β1 chain (1997) (36)
Structural interlock between ligand-binding site and stalk-like region of beta1 integrin revealed by a monoclonal antibody recognizing conformation-dependent epitope. (1997) (35)
Direct interaction of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin alpha v beta 3 induces signal transduction and enhances plasminogen activation. (2006) (35)
A fruiting body-specific cDNA, mfbAc, from the mushroom Lentinus edodes encodes a high-molecular-weight cell-adhesion protein containing an Arg-Gly-Asp motif. (1995) (35)
A structure-based model of substrate discrimination by a noncanonical PDZ tandem in the intramembrane-cleaving protease RseP. (2014) (34)
Changing ligand specificities of alphavbeta1 and alphavbeta3 integrins by swapping a short diverse sequence of the beta subunit. (1997) (33)
Inhibition of platelet-collagen interaction by propolypeptide of von Willebrand factor. (1989) (33)
Novel affinity tag system using structurally defined antibody‐tag interaction: Application to single‐step protein purification (2008) (32)
Functional Importance of Covalent Homodimer of Reelin Protein Linked via Its Central Region* (2011) (31)
Collagen-binding domain within bovine propolypeptide of von Willebrand factor. (1991) (30)
Propolypeptide of von Willebrand factor serves as a substrate for factor XIIIa and is cross-linked to laminin. (1993) (30)
Feedback regulation of platelet function by 12S-hydroxyeicosatetraenoic acid: inhibition of arachidonic acid liberation from phospholipids. (1990) (30)
A single chain 19-kDa fragment from bovine thrombospondin binds to type V collagen and heparin. (1993) (28)
A Novel Ca2+ Binding β Hairpin Loop Better Resembles Integrin Sequence Motifs Than the EF Hand (2000) (28)
A collagen-binding glycoprotein from bovine platelets is identical to propolypeptide of von Willebrand factor. (1989) (27)
αVβ6 Is a Novel Receptor for Human Fibrillin-1 (2007) (27)
Structural Basis of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2b Regulation via Transmembrane Helix Interplay. (2019) (27)
A multipurpose fusion tag derived from an unstructured and hyperacidic region of the amyloid precursor protein (2013) (26)
A rapid screening method for cell lines producing singly-tagged recombinant proteins using the "TARGET tag" system. (2010) (26)
Factor X‐dependent, thrombin‐generating activities on a neuroblastoma cell and their disappearance upon differentiation (1997) (25)
Molecular dissection of protein–protein interactions between integrin α5β1 and the Helicobacter pylori Cag type IV secretion system (2017) (25)
A systematic survey of conformational states in β1 and β4 integrins using negative-stain electron microscopy (2018) (25)
Identification of factor-XIIIa-reactive glutaminyl residues in the propolypeptide of bovine von Willebrand factor. (1995) (24)
Mechanistic basis for the recognition of laminin-511 by α6β1 integrin (2017) (23)
Comparison of the envelope architecture of E. coli using two methods: CEMOVIS and cryo-electron tomography. (2010) (23)
A point mutation in Semaphorin 4A associates with defective endosomal sorting and causes retinal degeneration (2013) (22)
Structural insights into integrin α5β1 opening by fibronectin ligand (2021) (22)
Venom from southern copperhead snake (Agkistrodon contortrix contortrix). II. A unique phospholipase A2 that induces platelet aggregation. (1988) (21)
Crystal structure and enzymatic activity of an ADAMTS‐13 mutant with the East Asian‐specific P475S polymorphism (2013) (21)
Key Interactions in Integrin Ectodomain Responsible for Global Conformational Change Detected by Elastic Network Normal-Mode Analysis (2008) (21)
Structure of the Plexin Ectodomain Bound by Semaphorin-Mimicking Antibodies (2016) (20)
Structural Basis for Variant-Specific Neuroligin-Binding by α-Neurexin (2011) (20)
Molecular Basis of the Ligand Binding Specificity of αvβ8 Integrin* (2016) (20)
Fv-clasp: An Artificially Designed Small Antibody Fragment with Improved Production Compatibility, Stability, and Crystallizability. (2017) (19)
Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus (2017) (19)
Three-dimensional architecture of virus-packed tubule. (2007) (18)
Structural basis for ligand capture and release by the endocytic receptor ApoER2 (2017) (18)
The 'ligand-induced conformational change' of alpha 5 beta 1 integrin. Relocation of alpha 5 subunit to uncover the beta 1 stalk region. (1998) (18)
Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations (2019) (17)
Structural mechanism of laminin recognition by integrin (2021) (17)
Monoclonal antibodies that inhibit binding of propolypeptide of von Willebrand factor to collagen. Localization of epitopes. (1991) (16)
High Affinity Ligand Binding by Integrins Does Not Involve Head Separation* (2003) (16)
Mechanistic insights into ectodomain shedding: susceptibility of CADM1 adhesion molecule is determined by alternative splicing and O-glycosylation (2017) (16)
Elucidation of a role of plasma albumin during collagen-induced aggregation of bovine platelets. (1989) (15)
An engineered ACE2 decoy neutralizes the SARS-CoV-2 Omicron variant and confers protection against infection in vivo (2022) (15)
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp1. (2012) (14)
High affinity modified ACE2 receptors prevent SARS-CoV-2 infection (2020) (14)
Inhibition of adenylyl cyclases by 12(S)-hydroxyeicosatetraenoic acid. (1996) (14)
β1‐integrin‐mediated adhesion of melanoma cells to the propolypeptide of von Willebrand factor (1994) (14)
The development of porcine zona pellucida using monoclonal antibodies: II. Electron microscopy. (1989) (14)
Laminin-121--recombinant expression and interactions with integrins. (2010) (13)
Structural basis for allostery in integrins and binding of ligand-mimetic therapeutics to the platelet receptor for fibrinogen (2004) (13)
Yeast Inner-Subunit PA-NZ-1 Labeling Strategy for Accurate Subunit Identification in a Macromolecular Complex through Cryo-EM Analysis. (2018) (13)
Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins (2020) (11)
Analysis of distribution of receptors among platelets by flow cytometry. (1987) (11)
Development of cyclic peptides with potent in vivo osteogenic activity through RaPID-based affinity maturation (2020) (11)
Differential role of protein tyrosine phosphorylation/dephosphorylation in affinity regulation of beta 1 and beta 3 integrin in human fibroblasts. (1995) (11)
The development of porcine zona pellucida using monoclonal antibodies: I. Immunochemistry and light microscopy. (1989) (11)
Structure of the F-spondin reeler domain reveals a unique beta-sandwich fold with a deformable disulfide-bonded loop. (2008) (11)
Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist (2018) (11)
Propolypeptide and mature portions of von Willebrand factor of bovine origin recognize different sites on type-I collagen obtained from bovine tendon. (1992) (10)
Site-specific epitope insertion into recombinant proteins using the MAP tag system (2020) (10)
Activity-independent cell adhesion to tissue-type transglutaminase is mediated by alpha4beta1 integrin. (1999) (10)
Venom from southern copperhead snake (Agkistrodon contortrix contortrix). I. Characterization of a protease that preferentially releases fibrinopeptide B. (1987) (10)
A murine monoclonal antibody that binds N-terminal extracellular segment of human protease-activated receptor-4. (2008) (9)
Structural basis for oligomerization of the prokaryotic peptide transporter PepTSo2 (2019) (9)
Engineered ACE2 counteracts vaccine-evading SARS-CoV-2 Omicron variant (2021) (9)
Structural and Functional Studies with Antibodies to the Integrin b 2 Subunit (2000) (9)
Impaired ligand‐dependent MET activation caused by an extracellular SEMA domain missense mutation in lung cancer (2019) (8)
Off-axis rotor in Enterococcus hirae V-ATPase visualized by Zernike phase plate single-particle cryo-electron microscopy (2018) (8)
Detection of endogenous LRP6 expressed on human cells by monoclonal antibodies specific for the native conformation. (2010) (8)
12‐Hydroxy‐5Z, 8Z, 10E, 14Z, eicosatetraenoic acid (12‐HETE) stimulates cAMP production in normal human fibroblasts (1999) (8)
Facile Synthesis of Dimeric Thioether-Macrocyclic Peptides with Antibody-like Affinity against Plexin-B1. (2018) (8)
An anti-peptide monoclonal antibody recognizing the tobacco etch virus protease-cleavage sequence and its application to a tandem tagging system. (2018) (8)
Plasma albumin is essential for collagen-induced platelet aggregation. (1988) (8)
Engineering ACE2 decoy receptors to combat viral escapability (2022) (7)
Production, crystallization and preliminary crystallographic analysis of an exosite-containing fragment of human von Willebrand factor-cleaving proteinase ADAMTS13 (2009) (7)
Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach (2019) (7)
Development of a new protein labeling system to map subunits and domains of macromolecular complexes for electron microscopy. (2017) (7)
Probing conformational and functional states of human hepatocyte growth factor by a panel of monoclonal antibodies (2016) (7)
The top of the inserted-like domain of the integrin lymphocyte function-associated antigen-1 beta subunit contacts the alpha subunit beta -propeller domain near beta-sheet 3. (2000) (7)
Beta 1-integrin-mediated adhesion of melanoma cells to the propolypeptide of von Willebrand factor. (1994) (7)
Crystallization and preliminary crystallographic analysis of human LR11 Vps10p domain. (2011) (6)
Anti–USAG-1 therapy for tooth regeneration through enhanced BMP signaling (2021) (6)
Negatively charged amino acids in the stalk region of membrane proteins reduce ectodomain shedding (2020) (6)
Mechanistic basis for the recognition of laminin-511 by alpha 6 beta 1 integrin. (2017) (6)
"A" subunit of factor XIII is present on bovine platelet membrane and mediates collagen-induced platelet activation. (1988) (6)
Structure of integrin a 5 b 1 in complex with ® bronectin (6)
Immunological detection of propolypeptide of von Willebrand factor on platelet surface. (1991) (6)
Foreword to ‘Multiscale structural biology: biophysical principles and mechanisms underlying the action of bio-nanomachines’, a special issue in Honour of Fumio Arisaka’s 70th birthday (2018) (6)
Macrocyclic peptides that inhibit Wnt signalling via interaction with Wnt3a (2020) (6)
Activation of phospholipases in platelets by polyclonal antibodies against a surface membrane protein. (1992) (5)
Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain (2022) (5)
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp6. (2014) (5)
Advances in domain and subunit localization technology for electron microscopy (2019) (5)
Schwann cell myelination requires integration of laminin activities (2013) (5)
Subunit B of factor XIII is present in bovine platelets. (1988) (5)
The PA Tag: A Versatile Peptide Tagging System in the Era of Integrative Structural Biology. (2018) (4)
Structural and Functional Studies with Antibodies to the Integrin β2 Subunit (2000) (4)
A new platelet aggregation factor from Gynostemma pentaphyllum Makino. (1985) (4)
2D hybrid analysis: Approach for building three-dimensional atomic model by electron microscopy image matching (2017) (4)
De novo peptide grafting to a self-assembling nanocapsule yields a hepatocyte growth factor receptor agonist (2021) (4)
Functional role of the Frizzled linker domain in the Wnt signaling pathway (2022) (4)
Albumin in plasma potentiates platelet aggregation induced by collagen--a study with an albumin deficient rat. (1990) (4)
Development of a Novel Peptide Affinity Tag System for One-Step Purification of Recombinant Proteins (2008) (4)
Crystal Structure of the LDL Receptor YWTD-EGF Domain Pair (2001) (3)
Structural studies of reelin N-terminal region provides insights into a unique structural arrangement and functional multimerization. (2020) (3)
Structural basis for multi-specific peptide recognition by the anti-IDH1/2 monoclonal antibody, MsMab-1. (2016) (3)
Crystal Structure of Reelin Repeats (2008) (3)
Tilt-angle measurement of a sample stage using a capacitive liquid-based inclinometer. (2012) (3)
De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function. (2022) (2)
The RGD motif in ﬁ bronectin is essential for development but dispensable for ﬁ bril assembly (2007) (2)
Serum autoantibodies against the extracellular region of α6β4 integrin in a patient with dipeptidyl peptidase-4 inhibitor–induced bullous pemphigoid (2021) (2)
Screening of hybridoma clones producing antibodies against plasma membrane-associated materials. (1998) (2)
The constitutive high affinity Met binding site in the kringle domain is dispensable for the signaling activity of hepatocyte growth factor. (2020) (2)
Corrigendum: Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors (2018) (2)
A feasibility study of inverse contrast-matching small-angle neutron scattering method combined with size exclusion chromatography using antibody interactions as model systems. (2021) (1)
Acquisition of resistance to wild-type spike-immune sera by emerging SARS-CoV-2 variants (2021) (1)
Designing receptor agonists with enhanced pharmacokinetics by grafting macrocyclic peptides into fragment crystallizable regions (2022) (1)
Interaction between plasma factor XIII and collagen. (1986) (1)
Molecular View of the Integrin Cell Adhesion Receptors (1998) (1)
Structural studies of α5β1 integrin ectodomain (2012) (1)
Hybrid in vitro/in silico analysis of low‐affinity protein–protein interactions that regulate signal transduction by Sema6D (2022) (1)
Postdoc Colloquium 2 : Implications for Familial Hypercholesterolemia from Structure of the LDL Receptor YWTD-EGF Domain Pair (2002) (1)
Relocation of α5 subunit to uncover the β1 stalk region (1998) (1)
Editorial overview: New constructs and expression of proteins: Making things better. (2014) (1)
Engineered fast-dissociating antibody fragments for multiplexed super-resolution microscopy (2022) (1)
Mouse Plexin A2 extracellular domain (2010) (0)
Molecular basis of binding selectivity between axon guidance cue semaphorin and its receptor plexin (2017) (0)
Crystal structure of SLE patient-derived anti-DNA antibody (2017) (0)
Crystal structure of mouse autotaxin in complex with 16:0-LPA (2011) (0)
Structural Basis of Sarco / Endoplasmic Reticulum Ca 2 +-ATPase 2 b Regulation via Transmembrane Helix Interplay Graphical (2019) (0)
Crystal structure of the third repeat domain of reelin (2006) (0)
1P055 Development of Three-Dimensional Reconstruction System by integration of many processing tools(Proteins-methodology,Poster Presentations) (2007) (0)
Wnt 2022 EMBO | the Company of Biologists workshop and Yamada conference (2023) (0)
A study of improvement of the crystal structural resolution of VSOP/Hv1 using PA tag (2016) (0)
Crystal structure of human F-spondin reeler domain (fragment 2) (2008) (0)
Structural and Functional Studies with Antibodies to the Integrin b2 Subunit (2000) (0)
26. Development of Porcine Zona Pellucida with Monoclonal Antibodies (1988) (0)
3P-069 Development of Three-Dimensional Reconstruction System by integration of many processing tools(The 46th Annual Meeting of the Biophysical Society of Japan) (2008) (0)
Crystal structure of reelin in complex with its receptor (2008) (0)
Crystal structure of alpha5beta1 integrin headpiece (ligand-free form) (2012) (0)
Alternative splicing and O-glycosylation are determinants of the susceptibility of ADAM-mediated ectodomain shedding (2016) (0)
Cryo-EM structure of human integrin alpha5beta1 in the half-bent conformation (2021) (0)
Crystal structure of reelin N-terminal region (2019) (0)
Crystal structure of human F-spondin reeler domain (fragment 1) (2008) (0)
2P539 Development of GUI-based tools for three dimensional electron tomography(52. Bio-imaging,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006) (2006) (0)
Crystal structure of monoclonal anti-human podoplanin antibody NZ-1 with bound PA peptide (2016) (0)
[Development of a novel affinity tag system for the next generation structural biology]. (2009) (0)
Atomic Model Building from Low Resolution Electron Microscope Images of Integrin (2013) (0)
Theoretical Model of the Integrin Beta2 I-like Domain (2001) (0)
Foreword to ‘Multiscale structural biology: biophysical principles and mechanisms underlying the action of bio-nanomachines’, a special issue in Honour of Fumio Arisaka’s 70th birthday (2018) (0)
Integrin EGF-like module 3 from the beta-2 subunit (2002) (0)
3SB56 Structural rearrangement of integrins in transmembrane signaling (2004) (0)
SorLA Vps10p domain in complex with its own propeptide fragment (2015) (0)
Structure of SARS-CoV-2 spike receptor-binding domain complexed with high affinity ACE2 mutant 3N39 (2020) (0)
[Platelet factor XIII as the collagen receptor]. (1987) (0)
Platelet Factor XI 11 THE COLLAGEN RECEPTOR ? (2001) (0)
[Transient signalling complex formed by axon guidance cue semaphorin]. (2011) (0)
Structural analysis of NZ-1 Fab complexed with PA peptide (2014) (0)
The periplasmic PDZ tandem fragment of the RseP homologue from Aquifex aeolicus (2013) (0)
Wnt signaling complex (2019) (0)
[New era of structural analysis of proteins by electron microscopy-application to a dynamic structural analysis of integrin cell adhesion receptor-]. (2005) (0)
Crystal structure of P20.1 Fv-clasp fragment with its antigen peptide (2017) (0)
SorLA Vps10p domain in ligand-free form (2015) (0)
Crystal structure of high affinity alphaL I domain in the absence of ligand or metal (2003) (0)
Structural Mechanism of Molecular Interaction Triggered by Synaptic Adhesion Protein (2008) (0)
[First atomic view of alpha V beta 3 integrin extracellular domain]. (2002) (0)
Molecular recognition of a single-chain Fv antibody specific for GA-pyridine, an advanced glycation end-product (AGE), elucidated using biophysical techniques and synthetic antigen analogues. (2021) (0)
Introduction to "neobiologics", a new modality of protein drugs developed by using LassoGraft Technology TM (2019) (0)
3P017 2D hybrid analysis: A new approach to build 3D atomic model from 2D EM image(01A. Protein: Structure,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014)) (2014) (0)
Crystal structure of Plexin inhibitor complex (2016) (0)
A novel protocol for biologically active Wnt protein preparation (2016) (0)
Alpha-Neurexin-1 ectodomain fragment; LNS5-EGF3-LNS6 (2011) (0)
Elucidating the structural features of the signaling molecule reelin by x-ray crystallography (2008) (0)
Crystal structure of high affinity alphaL I domain with ligand mimetic crystal contact (2003) (0)
Development of purification protocol of affinity tag-inserted multi-spanning membrane protein (2017) (0)
Three-dimensional reconstruction of human LRP6 ectodomain complexed with Dkk1 (2017) (0)
S-SAD phasing trials of human afamin (2016) (0)
headpiece with a glycan wedge increases (2016) (0)
Crystal structure of mouse autotaxin in complex with 22:6-LPA (2011) (0)
Crystal structure of 73MuL9 Fv-clasp fragment in complex with GA-pyridine analogue (2020) (0)
Tandem YVTN beta-propeller and PKD domains from an archaeal surface layer protein (2002) (0)
2D hybrid analysis: Approach for building three-dimensional atomic model by electron microscopy image matching (2017) (0)
Crystal structure of alpha5beta1 integrin headpiece in complex with RGD peptide (2012) (0)
Structural basis for peptide ligand recognition by SorLA Vps10p domain (2013) (0)
3P032 Substrate discrimination mechanism by a PDZ tandem in the intramembrane protease RseP that regulates extracytoplasmic stress response(01A. Protein: Structure,Poster) (2013) (0)
Crystal structure of two repeat fragment of reelin (2007) (0)
Structure of alpha6beta1 integrin in complex with laminin-511 (2021) (0)
Crystal structure of mouse autotaxin (2011) (0)
Crystal Structure of the Integrin αIIBβ3 Headpiece at 2.7–3.1 Å: Structure, Mechanisms of Activation and Ligand Binding, Inhibition by Eptifibatide, Tirofiban, and mAb 10E5, and Structure of the HPA-1 Alloantigen Epitope. (2004) (0)
Crystal structure of the LA12 fragment of ApoER2 (2017) (0)
[Multiple discontinuous exosites for von Willebrand factor of ADAMTS13]. (2010) (0)
Crystal structure of P20.1 Fab fragment in complex with its antigen peptide (2008) (0)
Structures of the laminin-binding integrins (2008) (0)
Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-2) (2009) (0)
106. Quantitative Changes of Estradiol Binding Protein Binding Capacity during the Normal Menstrual Cycle (1984) (0)
Crystal structure of monoclonal anti-human podoplanin antibody NZ-1 (2016) (0)
Plexin A2 / Semaphorin 6A complex (2010) (0)
Structural Analysis of Modular Proteins ; A Case of Integrin Head Fragment (2006) (0)
Structural determination of two-chain HGF fragments for the understanding of HGF/c-Met signaling (2016) (0)
Crystal structure of alphaL I domain in complex with ICAM-1 (2003) (0)
393.Comparison of Androgen Binding Proteins in the Cytosol of Hydatidiform Mole and Chorionic Villi of Normal Early Pregnancy : XXXXXXVII Trophoblastic Tumor(II) (1983) (0)
Structural Biology of the Reelin, a Large Extracellular Protein Regulating the Brain Development (2008) (0)
The periplasmic PDZ tandem fragment of the RseP homologue from Aquifex aeolicus in complex with the Fab fragment (2013) (0)
Author response: Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin (2015) (0)
1P043 Snap residues of integrin activation identified by elastic network normal mode analysis(Proteins-functions,Poster Presentations) (2007) (0)
Concerted conformational rearrangements within extracellular, intracellular, and transmembrane domains of integrins that govern ultimate ligand affinity (2003) (0)
Cryo-EM structure of human integrin alpha5beta1 (open form) in complex with fibronectin and TS2/16 Fv-clasp (2021) (0)
Crystal structure of a Fab fragment with its ligand peptide (2016) (0)
Off-axis rotor in Enterococcus hirae V-ATPase visualized by Zernike phase plate single-particle cryo-electron microscopy (2018) (0)
Crystal structure of the exosite-containing fragment of human ADAMTS13 (form-1) (2009) (0)
Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex (2023) (0)
Immunoaffinity Purification of the Glycosylated Extracellular Fragment of Mouse Plexin A2 Produced in a Mammalian Expression System. (2017) (0)
Crystal structure of the ApoER2 ectodomain in complex with the Reelin R56 fragment (2017) (0)
Structural study on the F-spondin reeler domain revealed a deformable disulfide-bonded loop in the E-sandwich structure (2009) (0)
Crystal structure of human Afamin, a serum glycoprotein that solubilize lipidated Wnt proteins (2016) (0)
Characterization of monoclonal antibody against bovine afamin (2016) (0)
Tetrameric PepTSo2 incorporated in salipro nano particle (2019) (0)
[Dynamic regulation of receptor transmembrane domain assembly during signal transmission across the plasma membrane]. (2005) (0)
Crystal structure of TS2/16 Fv-clasp fragment (2017) (0)
Crystal structure of Nidogen/Laminin Complex (2003) (0)
Conformational freedom of LRP6 ectodomain is regulated by N-glycosylation (2016) (0)
Crystal structure of SLE patient-derived anti-DNA antibody in complex with oligonucleotide (2017) (0)
An engineered ACE2 decoy broadly neutralizes Omicron subvariants and shows therapeutic effect in SARS-CoV-2-infected cynomolgus macaques (2023) (0)
Advances in domain and subunit localization technology for electron microscopy (2019) (0)
Crystal structure of a mammalian Wnt–frizzled complex (2019) (0)
Crystal structure of synaptic adhesion protein neurexin and neuroligin (2008) (0)
SorLA Vps10p domain directly recognizes Amyloid-β peptide (2013) (0)
Mathematical modeling and analysis of the pathway network consisting of symmetrical complexes with N monomers , like the activation of MMP 2 (2018) (0)
3P288 Development of GUI-based tools for three dimensional electron tomography(Bioimaging,Poster Presentations) (2007) (0)
Structure and mechanism of cancer-associated N-acetylglucosaminyltransferase-V (2018) (0)
Direct Cryo-ET observation of platelet deformation induced by SARS-CoV-2 Spike protein (2022) (0)
Crystal Structure of Neurexin 1beta/Neuroligin 1 complex (2012) (0)
Cellular signaling and gene expression profiles evoked by a bivalent macrocyclic peptide that serves as an artificial MET receptor agonist (2018) (0)
Development of fast-dissociating recombinant antibody probes for multiplexed super-resolution molecular mapping (2022) (0)
Direct Cryo-ET observation of platelet deformation induced by SARS-CoV-2 spike protein (2023) (0)
2P013 A new approach to build 3D atomic model from single electron microsope image(01A. Protein: Structure,Poster) (2013) (0)
Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization (2018) (0)
Clonal evolution and antigen recognition of anti-nuclear antibodies in acute systemic lupus erythematosus (2017) (0)
Advances in tooth agenesis and tooth regeneration (2023) (0)
Structure-Based Discovery of a Novel Class of Small-Molecule Pure Antagonists of Integrin αVβ3 (2022) (0)
Three-dimensional motions of GroEL during substrate protein recognition (2022) (0)
Lasso-grafting of macrocyclic peptide pharmacophores yields multi-functional proteins (2021) (0)
Structural analysis of antibody complexes by inverse contrast-matching small-angle neutron scattering combined with size-exclusion chromatography (SEC-iCM-SANS) (2021) (0)
Mechanistic Basis for the Laminin Recognition by Integrin (2019) (0)
Specific desensitization in the cytoskeletal assembly of platelet by receptor-dependent activations. (1986) (0)
Conformational activation of 2 integrins, their I domains, and regulation by small molecule antagonists (2002) (0)
Substrate discrimination by size-exclusion in the intramembrane protease RseP (2014) (0)
Structural analysis of PDZ modules of bacterial site-2 protease (2010) (0)
Crystal structure of mouse autotaxin in complex with 18:1-LPA (2011) (0)
Crystal structure of the exosite-containing fragment of human ADAMTS13 (P475S mutant) (2012) (0)
t8E4 antibody Fab complexed with the active form of HGF (2020) (0)
Crystal structure of mouse autotaxin in complex with 18:3-LPA (2011) (0)
Crystal structure of mouse autotaxin in complex with 14:0-LPA (2011) (0)
Investigation and optimization of the PA-tag insertion sites within the target protein towards cocrystallization with the NZ-1 fragments (2017) (0)
Crystal Structure of Autotaxin, a Lysophospholipase D that Produces Lipid Mediator Lysophosphatidic Acids (2011) (0)
SorLA Vps10p domain in complex with Abeta-derived peptide (2015) (0)
of the kringle domain of urokinase-type plasminogen activator (uPA) and integrin induces signal transduction and enhances plasminogen activation. (2006) (0)
Dissection of α4β7 integrin regulation by Rap1 using novel conformation-specific monoclonal anti-β7 antibodies (2020) (0)
Mouse Semaphorin 6A extracellular domain (2010) (0)

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