Junken Aoki
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Computer Science
Junken Aoki's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science Kyoto University
- Bachelors Computer Science Kyoto University
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(Suggest an Edit or Addition)Junken Aoki's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Autotaxin has lysophospholipase D activity leading to tumor cell growth and motility by lysophosphatidic acid production (2002) (892)
- Nectin/PRR: An Immunoglobulin-like Cell Adhesion Molecule Recruited to Cadherin-based Adherens Junctions through Interaction with Afadin, a PDZ Domain–containing Protein (1999) (555)
- Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist (2002) (544)
- Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor, EDG7, for Lysophosphatidic Acid* (1999) (505)
- LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing (2005) (495)
- Autotaxin Stabilizes Blood Vessels and Is Required for Embryonic Vasculature by Producing Lysophosphatidic Acid* (2006) (452)
- Two pathways for lysophosphatidic acid production. (2008) (406)
- Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways* (2002) (401)
- Structure and function of Zucchini endoribonuclease in piRNA biogenesis (2012) (305)
- Mechanisms of lysophosphatidic acid production. (2004) (293)
- The sphingosine-1-phosphate transporter Spns2 expressed on endothelial cells regulates lymphocyte trafficking in mice. (2012) (282)
- Lysophosphatidic Acid and Autotaxin Stimulate Cell Motility of Neoplastic and Non-neoplastic Cells through LPA1* (2004) (280)
- Illuminating G-Protein-Coupling Selectivity of GPCRs (2019) (278)
- TGFα shedding assay: an accurate and versatile method for detecting GPCR activation (2012) (272)
- Lack of beta-arrestin signaling in the absence of active G proteins (2018) (263)
- The experimental power of FR900359 to study Gq-regulated biological processes (2015) (251)
- Lysophosphatidic acid (LPA) receptors of the EDG family are differentially activated by LPA species (2000) (250)
- Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis (2017) (248)
- Autotaxin Is Overexpressed in Glioblastoma Multiforme and Contributes to Cell Motility of Glioblastoma by Converting Lysophosphatidylcholine TO Lysophosphatidic Acid* (2006) (238)
- Autotaxin hydrolyzes sphingosylphosphorylcholine to produce the regulator of migration, sphingosine-1-phosphate. (2003) (232)
- Crystal structure of autotaxin and insight into GPCR activation by lipid mediators (2011) (227)
- Autotaxin--an LPA producing enzyme with diverse functions. (2010) (208)
- Phenotypic Modulation of Vascular Smooth Muscle Cells Induced by Unsaturated Lysophosphatidic Acids (2001) (204)
- A therapeutic agent with oriented carbohydrates for treatment of infections by Shiga toxin-producing Escherichia coli O157:H7 (2002) (189)
- A Novel Phosphatidic Acid-selective Phospholipase A1That Produces Lysophosphatidic Acid* (2002) (186)
- Both Plasma Lysophosphatidic Acid and Serum Autotaxin Levels are Increased in Chronic Hepatitis C (2007) (181)
- Constitutive and lysophosphatidic acid (LPA)-induced LPA production: role of phospholipase D and phospholipase A2. (2000) (175)
- Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer (1997) (172)
- Lysophosphatidic acid as a lipid mediator with multiple biological actions. (2015) (164)
- Identification of a PDZ-domain-containing protein that interacts with the scavenger receptor class B type I. (2000) (158)
- Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures (2020) (155)
- Aberrant expression of lysophosphatidic acid (LPA) receptors in human colorectal cancer (2004) (154)
- Biological roles of lysophosphatidic acid signaling through its production by autotaxin. (2010) (154)
- Genetic evidence that β-arrestins are dispensable for the initiation of β2-adrenergic receptor signaling to ERK (2017) (149)
- Structure and function of extracellular phospholipase A1 belonging to the pancreatic lipase gene family. (2007) (141)
- Conformational transitions of a neurotensin receptor 1–Gi1 protein complex (2019) (139)
- Emerging lysophospholipid mediators, lysophosphatidylserine, lysophosphatidylthreonine, lysophosphatidylethanolamine and lysophosphatidylglycerol. (2009) (137)
- ADRP/adipophilin is degraded through the proteasome-dependent pathway during regression of lipid-storing cells Published, JLR Papers in Press, October 17, 2005. (2006) (137)
- Modulation of Human Immunodeficiency Virus Type 1 Infectivity through Incorporation of Tetraspanin Proteins (2007) (135)
- Serine Phospholipid-specific Phospholipase A That Is Secreted from Activated Platelets (1997) (134)
- Purification, cDNA Cloning, and Expression of UDP-Gal: Glucosylceramide β-1,4-Galactosyltransferase from Rat Brain* (1998) (129)
- Mouse homolog of poliovirus receptor-related gene 2 product, mPRR2, mediates homophilic cell aggregation. (1997) (127)
- Protection against Oxidative Stress-induced Cell Death by Intracellular Platelet-activating Factor-Acetylhydrolase II* (1997) (123)
- LPA‐producing enzyme PA‐PLA1α regulates hair follicle development by modulating EGFR signalling (2011) (120)
- Over-expression of lysophosphatidic acid receptor-2 in human invasive ductal carcinoma (2004) (119)
- Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma (2004) (117)
- Induction of autotaxin by the Epstein-Barr virus promotes the growth and survival of Hodgkin lymphoma cells. (2005) (117)
- Novel lysophosphoplipid receptors: their structure and function (2014) (115)
- Efficient delivery of circulating poliovirus to the central nervous system independently of poliovirus receptor. (1997) (114)
- The hydrolysis of lysophospholipids and nucleotides by autotaxin (NPP2) involves a single catalytic site (2003) (114)
- Involvement of the lysophosphatidic acid-generating enzyme autotaxin in lymphocyte-endothelial cell interactions. (2008) (113)
- GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites (2019) (112)
- Cancer Cell Expression of Autotaxin Controls Bone Metastasis Formation in Mouse through Lysophosphatidic Acid-Dependent Activation of Osteoclasts (2010) (111)
- Serum autotaxin measurement in haematological malignancies: a promising marker for follicular lymphoma (2008) (111)
- Biochemical and Molecular Characterization of a Novel Choline-specific Glycerophosphodiester Phosphodiesterase Belonging to the Nucleotide Pyrophosphatase/Phosphodiesterase Family* (2005) (110)
- Structure and function of phosphatidylserine-specific phospholipase A1. (2002) (109)
- Crystal structure of Enpp1, an extracellular glycoprotein involved in bone mineralization and insulin signaling (2012) (108)
- Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MS (2014) (107)
- Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine (2019) (107)
- Platelet-activating factor acetylhydrolase (PAF-AH). (2002) (107)
- Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain (2008) (106)
- Conformational transitions of a neurotensin receptor 1–Gi1 complex (2019) (105)
- Autotaxin (NPP-2) in the brain: cell type-specific expression and regulation during development and after neurotrauma (2006) (104)
- SEK1/MKK4-mediated SAPK/JNK signaling participates in embryonic hepatoblast proliferation via a pathway different from NF-kappaB-induced anti-apoptosis. (2002) (104)
- Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling (2009) (103)
- Identification of a Phosphothionate Analogue of Lysophosphatidic Acid (LPA) as a Selective Agonist of the LPA3 Receptor* (2003) (103)
- Plasma lysophosphatidic acid level and serum autotaxin activity are increased in liver injury in rats in relation to its severity. (2007) (103)
- Vascular Remodeling Induced by Naturally Occurring Unsaturated Lysophosphatidic Acid In Vivo (2003) (102)
- Validation of an autotaxin enzyme immunoassay in human serum samples and its application to hypoalbuminemia differentiation. (2008) (100)
- Constitutive Lymphocyte Transmigration across the Basal Lamina of High Endothelial Venules Is Regulated by the Autotaxin/Lysophosphatidic Acid Axis (2013) (98)
- Embryo Spacing and Implantation Timing Are Differentially Regulated by LPA3-Mediated Lysophosphatidic Acid Signaling in Mice1 (2007) (98)
- Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation (2018) (97)
- Transcription repressor Bach2 is required for pulmonary surfactant homeostasis and alveolar macrophage function (2013) (96)
- Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A2 in Mice Leads to Neonatal Lethality because of Lung Dysfunction* (2006) (95)
- Localization of α-tocopherol transfer protein in rat brain (1998) (94)
- Activation of mitogen-activated protein kinases by lysophosphatidylcholine-induced mitochondrial reactive oxygen species generation in endothelial cells. (2006) (93)
- A Novel Phospholipase A1 with Sequence Homology to a Mammalian Sec23p-interacting Protein, p125* (2002) (92)
- SREC-II, a New Member of the Scavenger Receptor Type F Family, Trans-interacts with SREC-I through Its Extracellular Domain* (2002) (89)
- Autotaxin as a novel serum marker of liver fibrosis. (2011) (88)
- Critical role of lysophospholipids in the pathophysiology, diagnosis, and management of ovarian cancer. (2002) (87)
- Structure of a microbial homologue of mammalian platelet-activating factor acetylhydrolases: Streptomyces exfoliatus lipase at 1.9 A resolution. (1998) (87)
- Biochemical and Molecular Characterization of Two Phosphatidic Acid-selective Phospholipase A1s, mPA-PLA1α and mPA-PLA1β* (2003) (87)
- cDNA Cloning and Expression of Intracellular Platelet-activating Factor (PAF) Acetylhydrolase II (1996) (86)
- Amino acid residues on human poliovirus receptor involved in interaction with poliovirus. (1994) (86)
- Targeted Disruption of Intracellular Type I Platelet Activating Factor-acetylhydrolase Catalytic Subunits Causes Severe Impairment in Spermatogenesis* (2003) (86)
- Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA‐binding proteins in activation of LPA receptors (2002) (85)
- Autotaxin Regulates Vascular Development via Multiple Lysophosphatidic Acid (LPA) Receptors in Zebrafish* (2011) (85)
- Autotaxin Regulates Maintenance of Ovarian Cancer Stem Cells through Lysophosphatidic Acid‐Mediated Autocrine Mechanism (2016) (84)
- Direct association of LIS1, the lissencephaly gene product, with a mammalian homologue of a fungal nuclear distribution protein, rNUDE (2000) (84)
- Expression patterns of the lysophospholipid receptor genes during mouse early development (2008) (83)
- Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6 (2017) (80)
- Cloning and Expression of a cDNA Encoding the -Subunit (30-kDa Subunit) of Bovine Brain Platelet-activating Factor Acetylhydrolase (*) (1995) (79)
- Glycerophospholipid regulation of modality-specific sensory axon guidance in the spinal cord (2015) (79)
- Interaction of Poliovirus with Its Purified Receptor and Conformational Alteration in the Virion (1998) (76)
- Autotaxin and lysophosphatidic acid1 receptor-mediated demyelination of dorsal root fibers by sciatic nerve injury and intrathecal lysophosphatidylcholine (2010) (76)
- Platelet-activating factor acetylhydrolase expression and activity suggest a link between neuronal migration and platelet-activating factor. (1996) (75)
- Evidence for De Novo Synthesis of Lysophosphatidic Acid in the Spinal Cord through Phospholipase A2 and Autotaxin in Nerve Injury-Induced Neuropathic Pain (2010) (75)
- Role of Nup98 in nuclear entry of human immunodeficiency virus type 1 cDNA. (2004) (73)
- ENPP2 Contributes to Adipose Tissue Expansion and Insulin Resistance in Diet-Induced Obesity (2014) (73)
- Switching of Platelet-activating Factor Acetylhydrolase Catalytic Subunits in Developing Rat Brain* (1998) (73)
- Phosphatidylserine-specific Phospholipase A1Stimulates Histamine Release from Rat Peritoneal Mast Cells through Production of 2-Acyl-1-lysophosphatidylserine* (2001) (72)
- Lysophosphatidic acid-3 receptor-mediated feed-forward production of lysophosphatidic acid: an initiator of nerve injury-induced neuropathic pain (2009) (71)
- Protection against Oxidative Stress-induced Hepatic Injury by Intracellular Type II Platelet-activating Factor Acetylhydrolase by Metabolism of Oxidized Phospholipids in Vivo* (2008) (70)
- Possible Involvement of Minor Lysophospholipids in the Increase in Plasma Lysophosphatidic Acid in Acute Coronary Syndrome (2015) (70)
- Identification of a Novel Member of the Carboxylesterase Family That Hydrolyzes Triacylglycerol (2006) (70)
- Neuronal Expression and Neuritogenic Action of Group X Secreted Phospholipase A2* (2005) (69)
- Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells. (2004) (69)
- α-Tocopherol Transfer Protein Is Specifically Localized at the Implantation Site of Pregnant Mouse Uterus (2002) (69)
- Nerve Growth Factor Activates Mast Cells Through the Collaborative Interaction with Lysophosphatidylserine Expressed on the Membrane Surface of Activated Platelets1 (2002) (68)
- Conformational Profiling of the AT1 Angiotensin II Receptor Reflects Biased Agonism, G Protein Coupling, and Cellular Context* (2017) (68)
- Necessity of lysophosphatidic acid receptor 1 for development of arthritis. (2013) (67)
- Cyclic Phosphatidic Acid Is Produced by Autotaxin in Blood* (2006) (67)
- Inactivating Mutations in GNA13 and RHOA in Burkitt’s Lymphoma and Diffuse Large B cell Lymphoma: A Tumor Suppressor Function for the Gα13/RhoA Axis in B Cells (2015) (66)
- Expression of Autotaxin and Acylglycerol kinase in prostate cancer: Association with cancer development and progression (2009) (66)
- Structure-activity relationships of fluorinated lysophosphatidic acid analogues. (2005) (66)
- Group VIB Ca2+-independent Phospholipase A2γ Promotes Cellular Membrane Hydrolysis and Prostaglandin Production in a Manner Distinct from Other Intracellular Phospholipases A2* (2005) (64)
- Biochemical Characterization of Various Catalytic Complexes of the Brain Platelet-activating Factor Acetylhydrolase* (1999) (63)
- Platelet-activating factor acetylhydrolases: broad substrate specificity and lipoprotein binding does not modulate the catalytic properties of the plasma enzyme. (2001) (63)
- Synthesis and evaluation of lysophosphatidylserine analogues as inducers of mast cell degranulation. Potent activities of lysophosphatidylthreonine and its 2-deoxy derivative. (2009) (61)
- GPR34 is a receptor for lysophosphatidylserine with a fatty acid at the sn-2 position. (2012) (60)
- An Alternative Splicing Form of Phosphatidylserine-specific Phospholipase A1 That Exhibits Lysophosphatidylserine-specific Lysophospholipase Activity in Humans* (1999) (59)
- A missense mutation within the helix initiation motif of the keratin K71 gene underlies autosomal dominant woolly hair/hypotrichosis. (2012) (59)
- Inhibition of Tumor Growth and Metastasis by Depletion of Vesicular Sorting Protein Hrs: Its Regulatory Role on E-Cadherin and β-Catenin (2007) (57)
- Measurement of lysophospholipase D/autotaxin activity in human serum samples. (2007) (56)
- Structural basis for specific inhibition of Autotaxin by a DNA aptamer (2016) (56)
- Specific increase in serum autotaxin activity in patients with pancreatic cancer. (2011) (56)
- Prevalent LIPH founder mutations lead to loss of P2Y5 activation ability of PA‐PLA1α in autosomal recessive hypotrichosis (2010) (55)
- X-ray structures of endothelin ETB receptor bound to clinical antagonist bosentan and its analog (2017) (54)
- Peritoneal fluids from patients with certain gynecologic tumor contain elevated levels of bioactive lysophospholipase D activity. (2007) (54)
- Human Placental Trophoblast Cells Express α-Tocopherol Transfer Protein (2003) (54)
- A novel peptide probe for studying the transbilayer movement of phosphatidylethanolamine. (1994) (54)
- Functional hemizygosity of PAFAH1B3 due to a PAFAH1B3-CLK2 fusion gene in a female with mental retardation, ataxia and atrophy of the brain. (2001) (54)
- Adiponectin suppresses tumorigenesis in Apc(Min)(/+) mice. (2010) (51)
- Intracellular Phospholipase A1γ (iPLA1γ) Is a Novel Factor Involved in Coat Protein Complex I- and Rab6-independent Retrograde Transport between the Endoplasmic Reticulum and the Golgi Complex* (2009) (51)
- Screening and X-ray crystal structure-based optimization of autotaxin (ENPP2) inhibitors, using a newly developed fluorescence probe. (2013) (51)
- Molecular Cloning and Characterization of a Novel Human G-protein-coupled Receptor , EDG 7 , for Lysophosphatidic Acid * (1999) (51)
- Neural cell adhesion molecule mediates contact-dependent inhibition of growth of near-diploid mouse fibroblast cell line m5S/1M (1991) (51)
- Crystal structures of human ETB receptor provide mechanistic insight into receptor activation and partial activation (2018) (50)
- Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase (2016) (50)
- PAF analogues capable of inhibiting PAF acetylhydrolase activity suppress migration of isolated rat cerebellar granule cells (1997) (49)
- Simultaneous stimulation of spinal NK1 and NMDA receptors produces LPC which undergoes ATX‐mediated conversion to LPA, an initiator of neuropathic pain (2008) (49)
- Enantioselective responses to a phosphorothioate analogue of lysophosphatidic acid with LPA3 receptor-selective agonist activity. (2003) (49)
- Lysophosphatidic receptor, LPA3, is positively and negatively regulated by progesterone and estrogen in the mouse uterus. (2006) (47)
- A 3D view of autotaxin. (2012) (47)
- Increased mRNA Levels of Sphingosine Kinases and S1P Lyase and Reduced Levels of S1P Were Observed in Hepatocellular Carcinoma in Association with Poorer Differentiation and Earlier Recurrence (2016) (46)
- Regulation of Intestinal IgA Responses by Dietary Palmitic Acid and Its Metabolism (2014) (46)
- Mitochondria‐type GPAT is required for mitochondrial fusion (2013) (45)
- Lysolipid receptor cross-talk regulates lymphatic endothelial junctions in lymph nodes (2019) (44)
- Identification of platelet-activating factor acetylhydrolase II in human skin. (2002) (44)
- β-Catenin asymmetry is regulated by PLA1 and retrograde traffic in C. elegans stem cell divisions (2008) (42)
- ORIGINAL ARTICLE: Expression of Autotaxin, an Ectoenzyme that Produces Lysophosphatidic Acid, in Human Placenta (2009) (42)
- Purinergic Receptor Transactivation by the β2-Adrenergic Receptor Increases Intracellular Ca2+ in Nonexcitable Cells (2017) (41)
- Serum autotaxin measurements in pregnant women: application for the differentiation of normal pregnancy and pregnancy-induced hypertension. (2011) (41)
- A CD63 mutant inhibits T-cell tropic human immunodeficiency virus type 1 entry by disrupting CXCR4 trafficking to the plasma membrane. (2008) (41)
- Inhibition of tumor growth and metastasis by depletion of vesicular sorting protein Hrs: its regulatory role on E-cadherin and beta-catenin. (2007) (41)
- Autotaxin-Lysophosphatidic Acid Pathway in Intraocular Pressure Regulation and Glaucoma Subtypes. (2018) (41)
- The 17,18‐epoxyeicosatetraenoic acid–G protein–coupled receptor 40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques (2017) (41)
- Analysis of lissencephaly-causing LIS1 mutations. (1999) (40)
- Characterization of three different transgenic mouse lines that carry human poliovirus receptor gene—influence of the transgene expression on pathogenesis (2005) (40)
- LPA(3), a unique G protein-coupled receptor for lysophosphatidic acid. (2010) (40)
- Differential expression of lysophosphatidic acid receptor‐2 in intestinal and diffuse type gastric cancer (2006) (39)
- Identifying specific conformations by using a carbohydrate scaffold: discovery of subtype-selective LPA-receptor agonists and an antagonist. (2004) (39)
- Biochemical and molecular characterization of two phosphatidic acid-selective phospholipase A1s, mPA-PLA1alpha and mPA-PLA1beta. (2003) (38)
- Identification and biochemical characterization of a novel autotaxin isoform, ATXδ, with a four-amino acid deletion. (2012) (38)
- Sphingosine kinase-1, S1P transporter spinster homolog 2 and S1P2 mRNA expressions are increased in liver with advanced fibrosis in human (2016) (38)
- Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility (2016) (37)
- Structure-activity relationships of lysophosphatidylserine analogs as agonists of G-protein-coupled receptors GPR34, P2Y10, and GPR174. (2015) (36)
- LPA and its analogs-attractive tools for elucidation of LPA biology and drug development. (2008) (36)
- TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1. (2017) (36)
- trans-Fatty acids promote proinflammatory signaling and cell death by stimulating the apoptosis signal-regulating kinase 1 (ASK1)-p38 pathway (2017) (35)
- Diversified expression patterns of autotaxin, a gene for phospholipid‐generating enzyme during mouse and chicken development (2007) (35)
- Localization of alpha-tocopherol transfer protein in rat brain. (1998) (35)
- cDNA cloning and expression of human lactosylceramide synthase. (1999) (35)
- Regulation of Peroxisomal Lipid Metabolism by Catalytic Activity of Tumor Suppressor H-rev107* (2011) (35)
- Sphingosine 1-phosphate release from platelets during clot formation: close correlation between platelet count and serum sphingosine 1-phosphate concentration (2013) (35)
- Lysophosphatidic acid is associated with neuropathic pain intensity in humans: An exploratory study (2018) (34)
- Structure of the dopamine D2 receptor in complex with the antipsychotic drug spiperone (2020) (34)
- Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders (2018) (34)
- Structures of the 5-HT2A receptor in complex with the antipsychotics risperidone and zotepine (2019) (33)
- Heterotrimeric G Protein Subunit Gαq Is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs. (2020) (33)
- Tissue tropism and species specificity of poliovirus infection. (1994) (33)
- Lysophosphatidylserine suppresses IL-2 production in CD4 T cells through LPS3/GPR174. (2017) (33)
- Autotaxin–lysophosphatidic acid–LPA 3 signaling at the embryo‐epithelial boundary controls decidualization pathways (2017) (33)
- Neuroprotective Role of Transgenic PAF-Acetylhydrolase II in Mouse Models of Focal Cerebral Ischemia (2007) (32)
- Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures. (2020) (32)
- Platelet-activating factor (PAF)-dependent transacetylase and its relationship with PAF acetylhydrolases. (2000) (32)
- Lysophospholipids in laboratory medicine (2018) (31)
- Role of the Autotaxin-LPA Pathway in Dexamethasone-Induced Fibrotic Responses and Extracellular Matrix Production in Human Trabecular Meshwork Cells. (2018) (31)
- The Crystal Structure of Angiotensin II Type 2 Receptor with Endogenous Peptide Hormone. (2019) (31)
- Lysophosphatidylserine analogues differentially activate three LysoPS receptors. (2015) (31)
- Lysophosphatidic acid and ovarian cancer: a paradigm for tumorogenesis and patient management. (2001) (31)
- A Lentiviral cDNA Library Employing Lambda Recombination Used To Clone an Inhibitor of Human Immunodeficiency Virus Type 1-Induced Cell Death (2004) (30)
- Lysophosphatidylserine has Bilateral Effects on Macrophages in the Pathogenesis of Atherosclerosis. (2015) (30)
- Fluorescence probe for lysophospholipase C/NPP6 activity and a potent NPP6 inhibitor. (2011) (30)
- Probing the substrate specificity of the intracellular brain platelet-activating factor acetylhydrolase. (1999) (29)
- Blood levels of serotonin are specifically correlated with plasma lysophosphatidylserine among the glycero-lysophospholipids (2015) (29)
- Structure and selectivity engineering of the M1 muscarinic receptor toxin complex (2020) (29)
- LPA1, LPA2, LPA4, and LPA6 receptor expression during mouse brain development (2019) (29)
- Molecular mechanism of lysophosphatidic acid-induced hypertensive response (2019) (28)
- Lysophosphatidylcholine mediates fast decline in kidney function in diabetic kidney disease (2021) (28)
- Homologs of the α‐ and β‐subunits of mammalian brain platelet‐activating factor acetylhydrolase Ib in the Drosophila melanogaster genome (2000) (28)
- Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes (2015) (28)
- Synaptic PRG-1 Modulates Excitatory Transmission via Lipid Phosphate-Mediated Signaling (2011) (28)
- Serum lysophospholipase D/autotaxin may be a new nutritional assessment marker: study on prostate cancer patients (2007) (28)
- GPR34 in spinal microglia exacerbates neuropathic pain in mice (2019) (28)
- Human placental trophoblast cells express alpha-tocopherol transfer protein. (2003) (28)
- Identification of Celastramycin as a Novel Therapeutic Agent for Pulmonary Arterial Hypertension-High-throughput Screening of 5,562 Compounds. (2019) (27)
- Autotaxin Overexpression Causes Embryonic Lethality and Vascular Defects (2015) (27)
- Dietary Lactobacillus-Derived Exopolysaccharide Enhances Immune-Checkpoint Blockade Therapy (2022) (26)
- Nuclear-accumulated SQSTM1/p62-based ALIS act as microdomains sensing cellular stresses and triggering oxidative stress-induced parthanatos (2018) (26)
- Decrease in circulating autotaxin by oral administration of prednisolone. (2013) (25)
- A CD63 Mutant Inhibits T‐cell Tropic Human Immunodeficiency Virus Type 1 Entry by Disrupting CXCR4 Trafficking to the Plasma Membrane (2008) (25)
- Update and nomenclature proposal for mammalian lysophospholipid acyltransferases, which create membrane phospholipid diversity (2021) (25)
- Phosphorothioate analogs of sn-2 radyl lysophosphatidic acid (LPA): metabolically stabilized LPA receptor agonists. (2013) (25)
- Phosphorothioate Analogues of Alkyl Lysophosphatidic Acid as LPA3 Receptor‐Selective Agonists (2006) (25)
- Different origins of lysophospholipid mediators between coronary and peripheral arteries in acute coronary syndrome[S] (2017) (25)
- Analysis of glycero-lysophospholipids in gastric cancerous ascites[S] (2017) (24)
- LPP3 localizes LPA6 signalling to non-contact sites in endothelial cells (2015) (24)
- Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein (2019) (24)
- Performance of autotaxin as a serum marker for liver fibrosis (2018) (23)
- Phospholipase A1: structure, distribution and function (2006) (23)
- Synthetic biotinylated peptide compounds derived from Asp-hemolysin: novel potent inhibitors of platelet-activating factor. (2012) (23)
- Conformational biosensors reveal allosteric interactions between heterodimeric AT1 angiotensin and prostaglandin F2α receptors (2017) (23)
- A novel enzyme immunoassay for the determination of phosphatidylserine-specific phospholipase A(1) in human serum samples. (2010) (22)
- Autotaxin enzyme immunoassay in human cerebrospinal fluid samples. (2009) (21)
- Association between serum autotaxin or phosphatidylserine‐specific phospholipase A1 levels and melanoma (2018) (21)
- Lysophosphatidic acids and their substrate lysophospholipids in cerebrospinal fluid as objective biomarkers for evaluating the severity of lumbar spinal stenosis (2019) (21)
- ATX-LPA1 axis contributes to proliferation of chondrocytes by regulating fibronectin assembly leading to proper cartilage formation (2016) (20)
- Expression of NUDEL in manchette and its implication in spermatogenesis (2004) (20)
- Analysis of serum and urinary lysophospholipase D/autotaxin in nephrotic syndrome (2008) (20)
- Non-cell autonomous and non-catalytic activities of ATX in the developing brain (2015) (20)
- Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors. (2004) (20)
- Synthesis of migration-resistant hydroxyethoxy analogues of lysophosphatidic acid. (2003) (19)
- Comprehensive analysis of sphingosine‐1‐phosphate receptor mutants during zebrafish embryogenesis (2015) (19)
- LPA1 receptor–mediated thromboxane A2 release is responsible for lysophosphatidic acid‐induced vascular smooth muscle contraction (2017) (19)
- Submucosal connective tissue-type mast cells contribute to the production of lysophosphatidic acid (LPA) in the gastrointestinal tract through the secretion of autotaxin (ATX)/lysophospholipase D (lysoPLD) (2007) (19)
- Structure of SARS-CoV-2 membrane protein essential for virus assembly (2022) (19)
- Evidence Suggests Sphingosine 1‐Phosphate Might Be Actively Generated, Degraded, and Transported to Extracellular Spaces With Increased S1P2 and S1P3 Expression in Colon Cancer (2017) (19)
- Immunohistochemical Detection of Autotaxin (ATX)/Lysophospholipase D (lysoPLD) in Submucosal Invasive Colorectal Cancer (2011) (18)
- Heterotrimeric Gq proteins act as a switch for GRK5/6 selectivity underlying β-arrestin transducer bias (2022) (18)
- Current Knowledge on the Biology of Lysophosphatidylserine as an Emerging Bioactive Lipid (2021) (18)
- Endogenous agonist–bound S1PR3 structure reveals determinants of G protein–subtype bias (2021) (18)
- Serum phosphatidylserine‐specific phospholipase A1 as a novel biomarker for monitoring systemic lupus erythematosus disease activity (2019) (18)
- Increased aqueous autotaxin and lysophosphatidic acid levels are potential prognostic factors after trabeculectomy in different types of glaucoma (2018) (18)
- A Novel Human G‐Protein‐Coupled Receptor, EDG7, for Lysophosphatidic Acid With Unsaturated Fatty‐Acid Moiety (2000) (18)
- Potentials of the circulating pruritogenic mediator lysophosphatidic acid in development of allergic skin inflammation in mice: role of blood cell-associated lysophospholipase D activity of autotaxin. (2014) (18)
- Crystal structure of human endothelin ETB receptor in complex with peptide inverse agonist IRL2500 (2019) (18)
- Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation (2019) (18)
- LIS1 Missense Mutations (2003) (18)
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- Development of an ENPP1 fluorescence probe for inhibitor screening, cellular imaging and prognostic assessment of malignant breast cancer. (2019) (17)
- High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node (2019) (17)
- Maternal and Zygotic Sphingosine Kinase 2 Are Indispensable for Cardiac Development in Zebrafish* (2015) (17)
- Conductive Adhesive Film Expands the Utility of Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. (2019) (16)
- Analysis of urinary sphingolipids using liquid chromatography‐tandem mass spectrometry in diabetic nephropathy (2019) (16)
- N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand. (2021) (16)
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- The LPA2 receptor agonist Radioprotectin-1 spares Lgr5-positive intestinal stem cells from radiation injury in murine enteroids. (2018) (16)
- Simultaneous quantitation of sphingoid bases and their phosphates in biological samples by liquid chromatography/electrospray ionization tandem mass spectrometry (2012) (16)
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- Rare, functional, somatic variants in gene families linked to cancer genes: GPCR signaling as a paradigm (2019) (16)
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- Phosphatidylserine-specific phospholipase A1 (PS-PLA1) expression in colorectal cancer correlates with tumor invasion and hematogenous metastasis. (2015) (15)
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- Secreted phospholipase A2 modifies extracellular vesicles and accelerates B cell lymphoma. (2022) (15)
- Serum Autotaxin is not a Useful Biomarker for Ovarian Cancer (2012) (15)
- PAF and PAF acetylhydrolase in the nervous system. (1996) (15)
- Analysis of unique mutations in the LPAR6 gene identified in a Japanese family with autosomal recessive woolly hair/hypotrichosis: Establishment of a useful assay system for LPA6. (2015) (15)
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- Filopodium-derived vesicles produced by MIM enhance the migration of recipient cells. (2021) (14)
- Sphingosine 1 Phosphate (S1P) Increased IL-6 Expression and Cell Growth in Endometriotic Cells (2019) (14)
- A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias (2017) (14)
- Suppressing postcollection lysophosphatidic acid metabolism improves the precision of plasma LPA quantification (2021) (14)
- Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques (2022) (14)
- Overexpression of autotaxin, a lysophosphatidic acid-producing enzyme, enhances cardia bifida induced by hypo-sphingosine-1-phosphate signaling in zebrafish embryo. (2014) (14)
- Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp1. (2012) (14)
- Placental autotaxin expression is diminished in women with pre‐eclampsia (2015) (14)
- Neuromedin U directly induces degranulation of skin mast cells, presumably via MRGPRX2 (2018) (14)
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- Introducing the Lipidomics Minimal Reporting Checklist (2022) (13)
- Stepwise phosphorylation of leukotriene B4 receptor 1 defines cellular responses to leukotriene B4 (2018) (13)
- Conformational Constraint of the Glycerol Moiety of Lysophosphatidylserine Affords Compounds with Receptor Subtype Selectivity. (2016) (13)
- GPR34 as a lysophosphatidylserine receptor. (2013) (13)
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- An accurate and versatile method for determining the acyl group-introducing position of lysophospholipid acyltransferases. (2019) (13)
- Probing the Hydrophobic Binding Pocket of G-Protein-Coupled Lysophosphatidylserine Receptor GPR34/LPS1 by Docking-Aided Structure-Activity Analysis. (2017) (13)
- A New Enzyme Immunoassay for the Quantitative Determination of Classical Autotaxins (ATXα, ATXβ, and ATXγ) and Novel Autotaxins (ATXδ and ATXε) (2015) (13)
- Type II platelet-activating factor-acetylhydrolase is essential for epithelial morphogenesis in Caenorhabditis elegans. (2004) (13)
- The functional implications of the dimerization of the catalytic subunits of the mammalian brain platelet-activating factor acetylhydrolase (Ib). (2000) (13)
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- Identification of novel biomarkers of hepatocellular carcinoma by high‐definition mass spectrometry: Ultrahigh‐performance liquid chromatography quadrupole time‐of‐flight mass spectrometry and desorption electrospray ionization mass spectrometry imaging (2019) (12)
- Synaptic Phospholipid Signaling Modulates Axon Outgrowth via Glutamate-dependent Ca2+-mediated Molecular Pathways (2016) (12)
- Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells (2019) (12)
- Serum Autotaxin Levels Are Associated with Proteinuria and Kidney Lesions in Japanese Type 2 Diabetic Patients with Biopsy-proven Diabetic Nephropathy. (2016) (12)
- A novel mutation, c.699C>G (p.C233W), in the LIPH gene leads to a loss of the hydrolytic activity and the LPA6 activation ability of PA-PLA1α in autosomal recessive wooly hair/hypotrichosis. (2013) (12)
- A monoclonal antibody, 3A10, recognizes a specific amino acid sequence present on a series of developmentally expressed brain proteins. (1999) (12)
- Erratum: Identification of an intracellular receptor for lysophosphatidic acid (LPA): LPA is a transcellular PPARγ agonist (Proceedings of the National Academy of Sciences of the United States of America (January 7, 2003) 100:1 (131-136)) (2003) (12)
- Lysophosphatidic acid protection against apoptosis in the human pre‐B‐cell line Nalm‐6 (2007) (12)
- Establishment of a Measurement System for Sphingolipids in the Cerebrospinal Fluid Based on Liquid Chromatography-Tandem Mass Spectrometry, and Its Application in the Diagnosis of Carcinomatous Meningitis. (2020) (12)
- Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model (2019) (12)
- The β9 loop domain of PA-PLA1α has a crucial role in autosomal recessive woolly hair/hypotrichosis. (2012) (12)
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- Synthetic Biotinylated Peptide Compound, BP21, Specifically Recognizes Lysophosphatidylcholine Micelles (2012) (11)
- Synthesis and biological evaluation of optically active Ki16425. (2012) (11)
- Anti‐idiotypic monoclonal antibody recognizes a consensus recognition site for phosphatidylserine in phosphatidylserine‐specific monoclonal antibody and protein kinase C (1994) (11)
- Development of an On-Tissue Derivatization Method for MALDI Mass Spectrometry Imaging of Bioactive Lipids Containing Phosphate Monoester Using Phos-tag. (2021) (11)
- Integrative genomic and proteomic analyses identifies glycerol-3-phosphate acyltransferase as a target of low-dose ionizing radiation in EBV infected-B cells (2016) (11)
- Crystal structure of human endothelin ETB receptor in complex with peptide inverse agonist IRL2500 (2018) (10)
- Development of an Activity‐Based Probe for Autotaxin (2010) (10)
- Simultaneous analyses of urinary eicosanoids and related mediators identified tetranor-prostaglandin E metabolite as a novel biomarker of diabetic nephropathy (2021) (10)
- Human adiponectin receptor AdipoR1 assumes closed and open structures (2020) (10)
- Detection of physiological activities of G protein-coupled receptor-acting pharmaceuticals in wastewater. (2015) (10)
- Antioxidant vitamins and lysophospholipids are critical for inducing mouse spermatogenesis under organ culture conditions (2020) (9)
- Elevated phosphatidylserine-specific phospholipase A1 level in hyperthyroidism. (2020) (9)
- Surface loops of extracellular phospholipase A1 determine both substrate specificity and preference for lysophospholipids[S] (2012) (9)
- Inhibition of autotaxin activity ameliorates neuropathic pain derived from lumbar spinal canal stenosis (2021) (9)
- Sphingosine-1-Phosphate (S1P)-Related Response of Human Conjunctival Fibroblasts After Filtration Surgery for Glaucoma. (2017) (9)
- Proliferation of mouse endometrial stromal cells in culture is highly sensitive to lysophosphatidic acid signaling. (2017) (9)
- Selective inhibition of human inducible nitric oxide synthase by S‐alkyl‐L‐isothiocitrulline‐containing dipeptides (2001) (9)
- Lysophosphatidylmethanol is a pan lysophosphatidic acid receptor agonist and is produced by autotaxin in blood. (2009) (9)
- Mitsugumin 56 (hedgehog acyltransferase‐like) is a sarcoplasmic reticulum‐resident protein essential for postnatal muscle maturation (2015) (8)
- 1‐Fluoro‐2,4‐dinitrobenzene and its derivatives act as secretagogues on rodent mast cells (2017) (8)
- Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay (2018) (8)
- Sphingosine 1-Phosphate (S1P) in the Peritoneal Fluid Skews M2 Macrophage and Contributes to the Development of Endometriosis (2021) (8)
- Inhibition of Tumor Growth and Metastasis by Depletion of Vesicular Sorting Protein Hrs: Its Regulatory Role on E-Cadherin and B-Catenin (2007) (8)
- Dietary cis-9, trans-11-conjugated linoleic acid reduces amyloid β-protein accumulation and upregulates anti-inflammatory cytokines in an Alzheimer’s disease mouse model (2021) (7)
- High‐endothelial cell‐derived S1P regulates dendritic cell localization and vascular integrity in the lymph node (2019) (7)
- Expression of Phosphatidylserine-Specific Phospholipase A1 mRNA in Human THP-1-Derived Macrophages (2010) (7)
- Autotaxin controls caudal diencephalon‐mesencephalon development in the chick (2010) (7)
- Development of a Novel Intraocular-Pressure-Lowering Therapy Targeting ATX. (2019) (7)
- Phospholipase A1 Assays Using a Radiolabeled Substrate and Mass Spectrometry (2007) (7)
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- Non-naturally-occurring Regio Isomer of Lysophosphatidylserine Exhibits Potent Agonistic Activity Towards G Protein-coupled Receptors. (2020) (6)
- Genetic deletion of Autotaxin from CD11b+ cells decreases the severity of experimental autoimmune encephalomyelitis (2019) (6)
- Novel Potent ABCB1 Modulator, Phenethylisoquinoline Alkaloid, Reverses Multidrug Resistance in Cancer Cell. (2018) (6)
- Metabolic Dysregulation of the Lysophospholipid/Autotaxin Axis in the Chromosome 9p21 Gene SNP rs10757274 (2019) (6)
- Phospholipase A1 Structures, Physiological and Patho‐physiological Roles in Mammals (2005) (6)
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- Expression, purification, crystallization and preliminary X-ray crystallographic analysis of Enpp6. (2014) (5)
- Identification of lysophosphatidylthreonine with an aromatic fatty acid surrogate as a potent inducer of mast cell degranulation (2016) (5)
- Increase in serum levels of phosphatidylserine-specific phospholipase A1 in COVID-19 patients (2021) (5)
- Regulation of plasma glycero-lysophospholipid levels by lipoprotein metabolism. (2019) (5)
- Analysis of Urinary Sphingolipids using LC-MS/MS in Diabetic Nephropathy. (2019) (5)
- The Many Roles of Lysophospholipid Mediators and Japanese Contributions to This Field. (2022) (5)
- Evaluation of Factor Xa-Specific Chromogenic Substrate Assays and the Determination of Pharmacokinetics of Fondaparinux (2016) (5)
- Transgenic Expression of Group V, but Not Group X, Secreted Phospholipase A 2 in Mice Leads to Neonatal Lethality (2006) (4)
- Identification and biochemical characterization of a second zebrafish autotaxin gene (2019) (4)
- Autotaxin and soluble IL-2 receptor concentrations in cerebrospinal fluids are useful for the diagnosis of central nervous system invasion caused by haematological malignancies (2019) (4)
- Dynamic modulations of sphingolipids and glycerophospholipids in COVID‐19 (2022) (4)
- ENPP2 contributes to adipose tissue expansion in diet-induced obesity (2014) (4)
- Switching Lysophosphatidylserine G Protein-Coupled Receptor Agonists to Antagonists by Acylation of the Hydrophilic Serine Amine. (2021) (4)
- Konjac ceramide (kCer) regulates keratinocyte migration by Sema3A-like repulsion mechanism (2019) (4)
- Reduced Cerebrospinal Fluid Levels of Lysophosphatidic Acid Docosahexaenoic Acid in Patients With Major Depressive Disorder and Schizophrenia (2021) (4)
- Identification of potent in vivo autotaxin inhibitors that bind to both hydrophobic pocket and channel in the catalytic domain. (2020) (4)
- Molecular cloning of cDNAs encoding alpha1, alpha2, and beta subunits of rat brain platelet-activating factor acetylhydrolase. (1998) (4)
- 2-Carba-lysophosphatidic acid is a novel β-lysophosphatidic acid analogue with high potential for lysophosphatidic acid receptor activation and autotaxin inhibition (2021) (3)
- HLA epitopes detected by serology. (1990) (3)
- An ATX-LPA6-Gα13-ROCK axis shapes and maintains caudal vein plexus in zebrafish (2021) (3)
- Diversified expression patterns of autotaxin, a gene for phospholipid‐generating enzyme during mouse and chicken development (2007) (3)
- Measurement of the Spatial Distribution of S1P in Small Quantities of Tissues: Development and Application of a Highly Sensitive LC-MS/MS Method Combined with Laser Microdissection (2019) (3)
- A Phenylfurocoumarin Derivative Reverses ABCG2-Mediated Multidrug Resistance In Vitro and In Vivo (2021) (3)
- Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism (2022) (3)
- Adipose differentiation-related protein is degraded through the proteasome-dependent pathway during regression of lipid-storing cells (2005) (3)
- Lysophosphatidic acid3 receptor-mediated feed-forward production of lysophosphatidic acid : an initiator of nerve injury-induced neuropathic pain (2015) (3)
- Regulation of the lysophosphatidylserine and sphingosine 1‐phosphate levels in autologous whole blood by the pre‐storage leukocyte reduction (2016) (3)
- Membrane Phospholipid Analogues as Molecular Rulers to Probe the Position of Hydrophobic Contact Point of Lysophospholipid Ligands on the Surface of G-Protein-coupled Receptor during Membrane Approach. (2020) (3)
- Abnormal male reproduction and embryonic development induced by downregulation of a phospholipid fatty acid-introducing enzyme Lpgat1 in zebrafish (2022) (2)
- Phospholipase A(1) assays using a radiolabeled substrate and mass spectrometry. (2007) (2)
- Different Profiles of the Triad of Lysophosphatidylcholine, Lysophosphatidic Acid, and Autotaxin in Patients with Neuropathic Pain Diseases: a Preliminary Observational Study (2022) (2)
- Protection against oxidative stress-induced hepatic injury by intracellular type II PAF-acetylhydrolase by metabolism of oxidized phospholipids in vivo (2007) (2)
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- Dynamic modulations of urinary sphingolipid and glycerophospholipid levels in COVID-19 and correlations with COVID-19-associated kidney injuries (2022) (2)
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- Alkyl Lysophosphatidic Acid and Fluoromethylene Phosphonate Analogues as Metabolically-Stabilized Agonists for LPA Receptors. (2005) (1)
- Membrane Surface of Activated Platelets Lysophosphatidylserine Expressed on the Through the Collaborative Interaction with Nerve Growth Factor Activates Mast Cells (2002) (1)
- Domain structure and substrate specificity of the ecto-nucleotide pyrophosphatases NPP1-3 (2003) (1)
- Astrocytic ATX fuels synaptic phospholipid signaling involved in psychiatric disorders (2018) (1)
- [Lysophospholipid mediators]. (2009) (1)
- Zebrafish as a model animal for studying lysophosphatidic acid signaling (2015) (1)
- Heterotypic inter-GPCR ß-arrestin coupling regulates lymphatic endothelial junctional architecture in murine lymph nodes (2018) (1)
- Modulations of bioactive lipids and their receptors in postmortem Alzheimer’s disease brains (2022) (1)
- Changes in Lysophospholipid Components in Ulcerative Colitis and Colitis-associated Cancer (2022) (1)
- GPR34 in spinal microglia exacerbates neuropathic pain in mice (2019) (1)
- [TGFalpha shedding assay is useful for identifying ligands for orphan GPCRs]. (2013) (1)
- S1PR3-G12-biased agonist ALESIA targets cancer metabolism and promotes glucose starvation. (2021) (1)
- Neural Cell Adhesion Molecule Mediates Contact-dependent Inhibition ofGrowth of Near-diploid Mouse Fibroblast Cell Line m 5 S / IM (2002) (1)
- Suppression of amyloid‐β secretion from neurons by cis‐9, trans‐11‐octadecadienoic acid, an isomer of conjugated linoleic acid (2021) (1)
- The Role of Lysophosphatidic Acid on Airway Epithelial Cell Denudation in a Murine Heterotopic Tracheal Transplant Model (2015) (1)
- Lysophospholipid Mediators: Their Receptors and Synthetic Pathways (2015) (1)
- Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid (2020) (1)
- Identification of novel biomarkers of hepatocellular carcinoma by a high definition mass spectrometry; UHPLC-QTOF/MS and DESI-MSI. (2019) (1)
- Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease. (2023) (1)
- LPA6-RhoA signals regulate junctional complexes for polarity and morphology establishment of maturation stage ameloblasts. (2022) (1)
- Persistent elevation of lysophosphatidylcholine promotes radiation brain necrosis with microglial recruitment by P2RX4 activation (2022) (1)
- Decrease in serum levels of autotaxin in COVID-19 patients (2022) (1)
- Crystal structure of 5-HT2AR in complex with zotepine (2019) (1)
- Cryo-EM structure of the human PAC1 receptor coupled to an engineered heterotrimeric G protein (2020) (1)
- Sphingosine 1‐phosphate lyase facilitates cancer progression through converting sphingolipids to glycerophospholipids (2022) (1)
- TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis (2022) (1)
- Generation of LysoPS receptors TKO mice by CRISPR/Cas9-mediated genome engineering (2015) (0)
- Analysis of LPA 3 function in testis using LPA 3 selective agonist (2017) (0)
- Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism (2022) (0)
- Agonist screening of Oxytocin receptor for the development of therapeutic agents for autism spectrum disorders (2016) (0)
- Split-luciferase-based G protein biosensors (2017) (0)
- Medium-chain fatty acids suppress lipotoxicity-induced hepatic fibrosis via the immunomodulating receptor GPR84 (2020) (0)
- Lipid Mediators in Inflammation (2017) (0)
- Antagonist of sphingosine 1-phosphate receptor 3 reduces cold injury of rat donor hearts for transplantation. (2022) (0)
- Identification of intracellular substrate for phospholipase A (2015) (0)
- Drug Discovery by Re-searching Cancer Metabolism and Microenvironment (2017) (0)
- Identi fi cation and characterization of LPLAT7 as an sn -1-speci fi c lysophospholipid acyltransferase (2022) (0)
- Structure and Function of Phospholipase A 1 (2013) (0)
- Generation of HEK293 cells devoid of GPCR effector proteins (2015) (0)
- Analysis of 3.43Q-induced constitutively active GPCR (2017) (0)
- Autotaxin Is Involved In Pulmonary Edema During Acid-induced Acute Lung Injury (2010) (0)
- Crystal Structure of Autotaxin, a Lysophospholipase D that Produces Lipid Mediator Lysophosphatidic Acids (2011) (0)
- Lack of beta-arrestin signaling in the absence of active G proteins (2018) (0)
- Adhesion Contact-dependent Inhibition of Growth of Near-diploid Mouse Fibroblast Cell Line m5S/IM (2002) (0)
- Crystal structure of mouse autotaxin in complex with 22:6-LPA (2011) (0)
- GPR31-dependent dendrite protrusion of intestinal CX3CR1+ cells by bacterial metabolites (2019) (0)
- The presence and the role of S1P system in endometriosis (2016) (0)
- Crystal Structure of human ETB receptor in complex with Endothelin-3 (2018) (0)
- Crystal structure of mouse autotaxin (2011) (0)
- Identification of P2Y receptors with oleamide suppressing microglial inflammatory response (2018) (0)
- Ectodomain shedding of EGFR ligands serves as an activation readout for TRP channels (2023) (0)
- Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase in complex with phosphocholine (2016) (0)
- PD05-11 SERUM ANANDAMIDE AND LIPIDS ASSOCIATED WITH LINOLEIC ACID CAN DISTINGUISH INTERSTITIAL CYSTITIS AND BLADDER PAIN SYNDROME FROM OVERACTIVE BLADDER (2023) (0)
- Measuring Activation of Lipid G Protein-Coupled Receptors Using the TGF-α Shedding Assay (2015) (0)
- ATX-LPA axis regulates cell-cell adhesion in multiple cell types (2017) (0)
- Development of an On-tissue Derivatization Method for MALDI Mass Spectrometry Imaging of Bioactive Lipids Containing Phosphate Monoester Using Phos-tag (2021) (0)
- Crystal structure of mouse autotaxin in complex with 14:0-LPA (2011) (0)
- development of Non-Edg family lysophosphatidic acid receptors (LPA4-6) agonist (2017) (0)
- Analysis of signal transduction via BLT1 and BLT2 using TGFαcleavage assay system (2017) (0)
- Cover Picture: Development of an Activity-Based Probe for Autotaxin (ChemBioChem 16/2010) (2010) (0)
- Measurement of plasma choline in acute coronary syndrome: importance of suitable sampling conditions for this assay (2018) (0)
- A role of novel LysoPS receptors in GC formation (2017) (0)
- development of an accurate method for quantification of lysophosphatidic acids in blood (2015) (0)
- Lysophospholipids and their producing enzymes: Their pathological roles and potential as pathological biomarkers. (2023) (0)
- Generation of HEK293 cells devoid of Gαi proteins (2017) (0)
- Identification of functional murine homolog of primate-specific receptor, MRGX4, activated by oxidized phospholipid (2017) (0)
- Glaucoma Role of the Autotaxin-LPA Pathway in Dexamethasone-Induced Fibrotic Responses and Extracellular Matrix Production in Human Trabecular Meshwork Cells (2017) (0)
- Analysis of molecular mechanisms of phospholipids sn -1 position fatty acid remodeling (2017) (0)
- Transcriptome profiling of anhidrotic eccrine sweat glands reveals that olfactory receptors on eccrine sweat glands regulate perspiration in a ligand-dependent manner (2023) (0)
- Microanalysis of S1P by Column switching LC-MS/MS and Laser Microdissection (2015) (0)
- A single extracellular amino acid in Free Fatty Acid Receptor 2 defines antagonist species selectivity and G protein selection bias (2017) (0)
- Lysophosphatidic acid stimulates IL-10 production from murine peritoneal macrophage (2017) (0)
- AB0220 Serum phosphatidylserine-specific phospholipase A1 (PS-PLA1) is increased in active systemic lupus erythematosus (SLE) and is correlated with disease activity (2013) (0)
- Autotaxin/Lysophosphatidic Acid Axis Venules Is Regulated by the across the Basal Lamina of High Endothelial Constitutive Lymphocyte Transmigration (2013) (0)
- Molecular mechanism of lysophosphatidic acid-induced hypertensive response (2019) (0)
- Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells (2019) (0)
- Constitutively active GPR43 is crucial for proper leukocyte differentiation (2022) (0)
- Author response: Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility (2015) (0)
- Crystal structure of mouse autotaxin in complex with 16:0-LPA (2011) (0)
- Usefulness of lysophosphatidylcholine measurement in the cerebrospinal fluid for differential diagnosis of neuropathic pain: possible introduction into clinical laboratory testing. (2023) (0)
- Implication of an intracellular phospholipase A1, KIAA0725, in cycling of TGN46 by hydrolyzing phosphatidylethanolamine (2005) (0)
- Update on LIPID MAPS classification, nomenclature, and shorthand notation for MS-derived lipid structures. (2020) (0)
- Supplemental Information Synaptic bioactive phospholipid signaling : A new target for treating psychiatric disorders Running title : Bioactive lipids in psychiatric disorders (2018) (0)
- Regulation of PIEZO1 mechanosensitive ion channel by flip-flop of phosphatidylserine (2017) (0)
- Nuclear-accumulated SQSTM1/p62-based ALIS act as microdomains sensing cellular stresses and triggering oxidative stress-induced parthanatos (2018) (0)
- Phenotypic evaluation of constitutive GPCR/G-protein signaling in zebrafish embryos and larvae. (2022) (0)
- Heterotrimeric G Protein Subunit Gαq is a Master Switch for Gβγ-Mediated Calcium Mobilization by Gi-Coupled GPCRs (2020) (0)
- GPCR Ligand Screening using TGFα shedding assay (2015) (0)
- Analysis of intracellular phospholipase A1 in Caenorhbditis elegans (2005) (0)
- Abstract 2059: Novel roles for GNA13 and RHOA as tumor suppressor genes (2015) (0)
- LPA 3 receptor regulates endometrial proliferation. (2015) (0)
- Identification and characterization of LPLAT7 as an sn-1-specific lysophospholipid acyltransferase (2022) (0)
- Lysophosphatidic acid facilitates human keratinocyte differentiation through the LPAR1/LPAR5-Rho-ROCK-SRF axis and promotes skin barrier function (2018) (0)
- Autotaxin: A Unique Ecto‐Type Pyrophosphodiesterase with Diverse Functions (2013) (0)
- Abstract 14194: Sphingosine 1-Phosphate Possesses the Carrier-dependent Effects on the Plasminogen Activator Inhibitor 1 Expression in Adipocytes (2016) (0)
- Author response: High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node (2019) (0)
- Structure of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase (2016) (0)
- G protein-biased LPAR1 agonism promotes prototypic antidepressant effects (2022) (0)
- Correction: Synaptic phospholipids as a new target for cortical hyperexcitability and E/I balance in psychiatric disorders (2019) (0)
- Exploration of LPS2 agonist binding modes using the combination of a new hydrophobic scaffold and homology modeling. (2023) (0)
- Establishment of GPCR activation detecting system in zebrafish (2017) (0)
- Possible LPA receptors involved in IL-10 production (2017) (0)
- Role of novel lysophosphatidylserine receptors in autoimmune lymphoproliferative syndrome (2017) (0)
- Crystal structure of mouse autotaxin in complex with 18:3-LPA (2011) (0)
- LPA3 signal protects the heart against ischemic injury through activation of the vagus nerve (2015) (0)
- Lysophosphatidic acids regulates mast cell maturation (2015) (0)
- Emerging roles of lysophosphatidylserine as an immune modulator. (2023) (0)
- Lysophosphatidic acids and their substrate lysophospholipids in cerebrospinal fluid as objective biomarkers for evaluating the severity of lumbar spinal stenosis (2019) (0)
- Lipid-Orchestrated Acceleration of Epstein-Barr Virus-Induced B-Cell Lymphoma Via the Secreted Phospholipase A 2-Mediated Modification of Exosomes (2021) (0)
- Structural basis for lysophosphatidylserine recognition by GPR34 (2023) (0)
- Intestinal microbe-dependent ω3 lipid metabolite αKetoA prevents inflammatory diseases in mice and cynomolgus macaques (2022) (0)
- Distributions of CHN compounds in meteorites record organic syntheses in the early solar system (2023) (0)
- Crystal structure of mouse autotaxin in complex with 18:1-LPA (2011) (0)
- Molecular and biological characterization of choline-specific lysophospholipase C, NPP6 (2006) (0)
- Increased aqueous autotaxin and lysophosphatidic acid levels are potential prognostic factors after trabeculectomy in different types of glaucoma (2018) (0)
- Analysis of the role of ATX-LPA signaling in vessel formation using zebrafish (2017) (0)
- Mechanism of lysophosphatidic acid-induced hypertension in mouse (2015) (0)
- Conformational profiling of the AT 1 angiotensin II receptor 1 Conformational profiling of the AT 1 angiotensin II receptor reflects biased agonism , G protein coupling and cellular context (2017) (0)
- Cell surface flip-flop of phosphatidylserine is critical for PIEZO1-mediated myotube formation (2018) (0)
- Expression analysis of lysophosphatidic acid receptor and producing enzyme in pulmonary fibrosis in mice (2017) (0)
- Preventive and alleviative effects of LPA 3 signaling in a novel mouse model of acute exacerbation of idiopathic pulmonary fibrosis (2017) (0)
- Lysophosphatidylserine as an Inflammatory Mediator (2016) (0)
- Human adiponectin receptor AdipoR1 assumes closed and open structures (2020) (0)
- Dietary Palmitic Acid and Its Metabolism Regulation of Intestinal IgA Responses by (2014) (0)
- Comprehensive characterization of G protein coupling of GPCRs (2015) (0)
- Sphingosine 1-phosphate release from platelets during clot formation: close correlation between platelet count and serum sphingosine 1-phosphate concentration (2013) (0)
- X-RAY CRYSTAL STRUCTURE OF R22K MUTANT OF THE MAMMALIAN BRAIN PLATELET-ACTIVATING FACTOR ACETYLHYDROLASES (PAF-AH) (2000) (0)
- Heterotrimeric Gq proteins act as a switch for GRK5/6 selectivity underlying β-arrestin transducer bias (2022) (0)
- Generation of Gαi knock-out HEK293 cells illuminates Gαi-coupling diversity of GPCRs (2023) (0)
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