Jürgen C. Frölich
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German university teacher
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Mathematics
Jürgen C. Frölich's Degrees
- PhD Mathematics University of Bonn
- Masters Mathematics University of Bonn
- Bachelors Mathematics University of Bonn
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(Suggest an Edit or Addition)Jürgen C. Frölich's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Plasma concentration of asymmetrical dimethylarginine and mortality in patients with end-stage renal disease: a prospective study (2001) (1078)
- Effects of caffeine on plasma renin activity, catecholamines and blood pressure. (1978) (781)
- Biochemical evidence for impaired nitric oxide synthesis in patients with peripheral arterial occlusive disease. (1997) (517)
- Endothelial dysfunction and raised plasma concentrations of asymmetric dimethylarginine in pregnant women who subsequently develop pre-eclampsia (2003) (513)
- Urinary prostaglandins. Identification and origin. (1975) (494)
- Selective Attenuation of Endothelium‐Mediated Vasodilation in Atherosclerotic Human Coronary Arteries (1988) (463)
- Cardiovascular Effects of Systemic Nitric Oxide Synthase Inhibition With Asymmetrical Dimethylarginine in Humans (2004) (399)
- Asymmetric dimethylarginine plasma concentrations differ in patients with end-stage renal disease: relationship to treatment method and atherosclerotic disease. (1999) (380)
- Marked increase of asymmetric dimethylarginine in patients with incipient primary chronic renal disease. (2002) (376)
- Bartter's syndrome: a disorder characterized by high urinary prostaglandins and a dependence of hyperreninemia on prostaglandin synthesis. (1976) (326)
- Elevated L-arginine/dimethylarginine ratio contributes to enhanced systemic NO production by dietary L-arginine in hypercholesterolemic rabbits. (1996) (314)
- Dietary L-arginine reduces the progression of atherosclerosis in cholesterol-fed rabbits: comparison with lovastatin. (1997) (262)
- Supplementation of hypercholesterolaemic rabbits with L-arginine reduces the vascular release of superoxide anions and restores NO production. (1995) (261)
- Restoring vascular nitric oxide formation by L-arginine improves the symptoms of intermittent claudication in patients with peripheral arterial occlusive disease. (1998) (260)
- Urinary 8-iso-Prostaglandin F2&agr; as a Risk Marker in Patients With Coronary Heart Disease: A Matched Case-Control Study (2004) (259)
- Endogenous nitric oxide synthase inhibitors are responsible for the L‐arginine paradox (2000) (258)
- ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins. (2003) (238)
- L-arginine-induced vasodilation in healthy humans: pharmacokinetic-pharmacodynamic relationship. (1998) (235)
- A classification of NSAIDs according to the relative inhibition of cyclooxygenase isoenzymes. (1997) (234)
- Asymmetric Dimethylarginine, Blood Pressure, and Renal Perfusion in Elderly Subjects (2003) (214)
- Use of ibuprofen and methylprednisolone for the prevention of pain and swelling after removal of impacted third molars. (1995) (203)
- L-arginine induces nitric oxide-dependent vasodilation in patients with critical limb ischemia. A randomized, controlled study. (1996) (191)
- Oral L-arginine improves endothelial function in healthy individuals older than 70 years (2003) (189)
- Endothelium-derived relaxing factor from cultured human endothelial cells inhibits aggregation of human platelets. (1987) (186)
- Nitric oxide and inflammatory joint diseases. (1998) (179)
- The L-arginine-nitric oxide pathway: role in atherosclerosis and therapeutic implications. (1996) (172)
- L-arginine infusion decreases peripheral arterial resistance and inhibits platelet aggregation in healthy subjects. (1994) (162)
- Increased arachidonate in lipids after administration to man: Effects on prostaglandin biosynthesis (1975) (158)
- Vascular release of superoxide radicals is enhanced in hypercholesterolemic rabbits. (1994) (148)
- Diclofenac concentrations in synovial fluid and plasma after cutaneous application in inflammatory and degenerative joint disease. (1991) (144)
- Measurement of nitrite and nitrate in biological fluids by gas chromatography-mass spectrometry and by the Griess assay: problems with the Griess assay--solutions by gas chromatography-mass spectrometry. (1997) (144)
- The carcinoid flush. Provocation by pentagastrin and inhibition by somatostatin. (1978) (132)
- Regional differences in prostacyclin formation by the kidney. Prostacyclin is a major prostaglandin of renal cortex. (1978) (130)
- Interaction of spironolactone with ACE inhibitors or angiotensin receptor blockers: analysis of 44 cases (2003) (129)
- Quantitative determination of circulating and urinary asymmetric dimethylarginine (ADMA) in humans by gas chromatography-tandem mass spectrometry as methyl ester tri(N-pentafluoropropionyl) derivative. (2003) (124)
- Recombinant human erythropoietin enhances vasoconstrictor tone via endothelin-1 and constrictor prostanoids. (1996) (122)
- Metabolism of prostacyclin and 6-keto-prostaglandin F1 alpha in man. (1980) (120)
- Quantification of nitrite and nitrate in human urine and plasma as pentafluorobenzyl derivatives by gas chromatography-mass spectrometry using their 15N-labelled analogs. (1994) (117)
- Dietary L-arginine and alpha-tocopherol reduce vascular oxidative stress and preserve endothelial function in hypercholesterolemic rabbits via different mechanisms. (1998) (100)
- Response of Human Coronary Arteries to Aggregating Platelets: Importance of Endothelium‐Derived Relaxing Factor and Prostanoids (1988) (96)
- Dietary L-arginine decreases myointimal cell proliferation and vascular monocyte accumulation in cholesterol-fed rabbits. (1998) (96)
- Antidiuretic hormone increases renal prostaglandin synthesis in vivo. (1978) (96)
- The participation of prostaglandins in the control of renin release. (1979) (95)
- Prevention of postoperative swelling and pain by dexamethasone after operative removal of impacted third molar teeth (2004) (93)
- Extraction and chromatographic procedures for purification of prostaglandins, thromboxanes, prostacyclin, and their metabolites. (1978) (92)
- Divergence in urinary 8-iso-PGF2α (iPF2α-III, 15-F2t-IsoP) levels from gas chromatography–tandem mass spectrometry quantification after thin-layer chromatography and immunoaffinity column chromatography reveals heterogeneity of 8-iso-PGF2α: Possible methodological, mechanistic and clinical implicati (2003) (90)
- Urinary prostaglandins: site of entry into renal tubular fluid. (1977) (85)
- Assessment of nitric oxide synthase activity in vitro and in vivo by gas chromatography-mass spectrometry. (2000) (85)
- Inhibitors of acyl-coenzyme A:lysolecithin acyltransferase activate the production of endothelium-derived vascular relaxing factor. (1986) (85)
- Importance of NO/EDRF for glomerular and tubular function: studies in the isolated perfused rat kidney. (1992) (84)
- Nebivolol decreases systemic oxidative stress in healthy volunteers. (2000) (82)
- Inhibition of platelet aggregation by S‐nitroso‐cysteine via cGMP‐independent mechanisms: evidence of inhibition of thromboxane A2 synthesis in human blood platelets (1999) (79)
- Effects of diclofenac on lithium kinetics (1981) (79)
- Gas chromatographic-tandem mass spectrometric quantification of free 3-nitrotyrosine in human plasma at the basal state. (1999) (77)
- Relationship of asymmetric dimethylarginine to dialysis treatment and atherosclerotic disease. (2001) (76)
- Long-term administration of L-arginine, L-NAME, and the exogenous NO donor molsidomine modulates urinary nitrate and cGMP excretion in rats. (1994) (76)
- Low dialysance of asymmetric dimethylarginine (ADMA)--in vivo and in vitro evidence of significant protein binding. (2004) (76)
- Measurement of prostaglandins, thromboxanes, prostacyclin and their metabolites by gas liquid chromatography--mass spectrometry. (1978) (75)
- Exercise Increases Systemic Nitric Oxide Production in Men (1994) (75)
- Indomethacin increases plasma lithium. (1979) (73)
- Tandem mass spectrometric quantification of 8-iso-prostaglandin F2α and its metabolite 2,3-dinor-5,6-dihydro-8-iso-prostaglandin F2α in human urine (2000) (72)
- Urinary nitrate excretion is increased in patients with rheumatoid arthritis and reduced by prednisolone. (1995) (70)
- Cimetidine increases steady state plasma levels of propranolol. (1981) (70)
- Analysis of cysteine and N-acetylcysteine in human plasma by high-performance liquid chromatography at the basal state and after oral administration of N-acetylcysteine. (1998) (70)
- Impaired degradation of leukotrienes in patients with peroxisome deficiency disorders. (1992) (70)
- Development, validation and biomedical applications of stable-isotope dilution GC-MS and GC-MS/MS techniques for circulating malondialdehyde (MDA) after pentafluorobenzyl bromide derivatization: MDA as a biomarker of oxidative stress and its relation to 15(S)-8-iso-prostaglandin F2α and nitric oxide (2016) (69)
- Elevated plasma and urine levels of ADMA and 15(S)‐8‐iso‐PGF2α in end‐stage liver disease (2003) (67)
- The second generation of COX-2 inhibitors: what advantages do the newest offer? (2003) (67)
- Nitric oxide inhibits the secretion of T-helper 1- and T-helper 2-associated cytokines in activated human T cells. (1997) (66)
- Investigations of S-transnitrosylation reactions between low- and high-molecular-weight S-nitroso compounds and their thiols by high-performance liquid chromatography and gas chromatography-mass spectrometry. (1999) (65)
- Endothelium-derived relaxing factor influences renal vascular resistance. (1990) (64)
- Indomethacin but not aspirin increases plasma lithium ion levels. (1983) (62)
- Simplified HPLC method for urinary and circulating creatinine. (2004) (62)
- Cigarette smoking stimulates cysteinyl leukotriene production in man (1997) (62)
- Role of endogenous nitric oxide in circadian blood pressure regulation in healthy humans and in patients with hypertension or atherosclerosis. (2000) (61)
- URINARY NO3− EXCRETION AS AN INDICATOR OF NITRIC OXIDE FORMATION IN VIVO DURING ORAL ADMINISTRATION OF l‐ARGININE OR l‐NAME IN RATS (1996) (61)
- Electrospray ionization mass spectrometry of low-molecular-mass S-nitroso compounds and their thiols. (2000) (59)
- Effects of meloxicam and indomethacin on cyclooxygenase pathways in healthy volunteers. (1997) (58)
- ADMA (asymmetric dimethylarginine): an atherosclerotic disease mediating agent in patients with renal disease? (2001) (58)
- Growth hormone induces eNOS expression and nitric oxide release in a cultured human endothelial cell line (2003) (58)
- Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. (2005) (58)
- Determination of S-nitrosoglutathione in human and rat plasma by high-performance liquid chromatography with fluorescence and ultraviolet absorbance detection after precolumn derivatization with o-phthalaldehyde. (1999) (57)
- Hypercholesterolemia impairs basal nitric oxide synthase turnover rate: a study investigating the conversion of L-[guanidino-(15)N(2)]-arginine to (15)N-labeled nitrate by gas chromatography--mass spectrometry. (2004) (56)
- Platelet aggregation and thromboxane release induced by arachidonic acid, collagen, ADP and platelet-activating factor following low dose acetylsalicylic acid in man. (1986) (56)
- Lack of Oxidative Stress during Sustained Therapy with Isosorbide Dinitrate and Pentaerythrityl Tetranitrate in Healthy Humans: A Randomized, Double-Blind Crossover Study (2003) (56)
- Mechanisms of action of lipoxygenase and cytochrome P‐450‐mono‐oxygenase inhibitors in blocking endothelium‐dependent vasodilatation (1988) (54)
- Mechanism of antihypertensive action of ketanserin in man. (1983) (54)
- Effect of dexamethasone on in vivo prostanoid production in the rabbit. (1984) (53)
- Glutathione promotes prostaglandin H synthase (cyclooxygenase)‐dependent formation of malondialdehyde and 15(S)‐8‐iso‐prostaglandin F2α (2012) (53)
- Endothelin Release and Shift in Prostaglandin Balance Are Involved in the Modulation of Vascular Tone by Recombinant Erythropoietin (1992) (52)
- Specific and rapid quantification of 8-iso-prostaglandin F2alpha in urine of healthy humans and patients with Zellweger syndrome by gas chromatography-tandem mass spectrometry. (1998) (50)
- Endothelium-dependent relaxation of human epicardial coronary arteries: frequent lack of effect of acetylcholine. (1986) (50)
- Measurement of S-nitrosoalbumin by gas chromatography-mass spectrometry. II. Quantitative determination of S-nitrosoalbumin in human plasma using S-[15N]nitrosoalbumin as internal standard. (1999) (50)
- High performance liquid chromotography of prostaglandins: biological applications. (1976) (49)
- Effects of cimetidine and ranitidine on steady‐state propranolol kinetics and dynamics (1982) (48)
- Elevated nitric oxide levels in patients with chronic liver disease and cirrhosis correlate with disease stage and parameters of hyperdynamic circulation. (2002) (47)
- Effects of acetylsalicylic acid and paracetamol alone and in combination on prostanoid synthesis in man. (1990) (47)
- Identification of the major metabolite of prostacyclin and 6-ketoprostaglandin F1α in man (1980) (46)
- Measurement of S-nitrosoalbumin by gas chromatography--mass spectrometry. III. Quantitative determination in human plasma after specific conversion of the S-nitroso group to nitrite by cysteine and Cu(2+) via intermediate formation of S-nitrosocysteine and nitric oxide. (2002) (46)
- Deciduogenic effect of prostaglandins in the pseudopregnant rabbit. (1977) (46)
- Effects of salicylic and acetylsalicylic acid alone and in combination on platelet aggregation and prostanoid synthesis in man. (1986) (45)
- Comparison of different activity parameters in atopic dermatitis: correlation with clinical scores (2002) (45)
- Dexamethasone effect on prostanoid formation in healthy man. (1985) (45)
- L-arginine stimulates NO-dependent vasodilation in healthy humans--effect of somatostatin pretreatment. (1999) (44)
- Accurate quantification of basal plasma levels of 3-nitrotyrosine and 3-nitrotyrosinoalbumin by gas chromatography-tandem mass spectrometry. (2003) (44)
- Endothelium-derived relaxing factor is likely to modulate the tone of resistance arteries in rabbit hindlimb in vivo. (1987) (43)
- Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free l-arginine in humans (2015) (43)
- Prostacyclin metabolites in human plasma (1981) (42)
- Enhanced synthesis of cysteinyl leukotrienes in atopic dermatitis (1993) (42)
- S-Transnitrosylation of albumin in human plasma and blood in vitro and in vivo in the rat. (2001) (42)
- Relevance of urinary 6-keto-prostaglandin F1α determination (1981) (42)
- Endothelial cyclic GMP and cyclic AMP do not regulate the release of endothelium-derived relaxing factor/nitric oxide from bovine aortic endothelial cells. (1991) (42)
- Determination of dimethylated arginines in human plasma by high-performance liquid chromatography. (1998) (40)
- Divergence in urinary 8-iso-PGF(2alpha) (iPF(2alpha)-III, 15-F(2t)-IsoP) levels from gas chromatography-tandem mass spectrometry quantification after thin-layer chromatography and immunoaffinity column chromatography reveals heterogeneity of 8-iso-PGF(2alpha). Possible methodological, mechanistic an (2003) (39)
- Effect of arginine depletion on glomerular and tubular kidney function: studies in isolated perfused rat kidneys. (1991) (38)
- Effect of selective inhibition of the inducible cyclooxygenase on renin release in healthy volunteers. (1998) (38)
- Rapid and selective inhibition of platelet aggregation and thromboxane formation by intravenous low dose aspirin in man. (1993) (38)
- Increased urinary nitrate excretion in rats with adjuvant arthritis. (1994) (38)
- Exercise increases systemic nitric oxide production in men. (1995) (38)
- Effects of very low dose and enteric-coated acetylsalicylic acid on prostacyclin and thromboxane formation and on bleeding time in healthy subjects (1998) (37)
- Endothelium-derived relaxing factor (EDRF): a defence mechanism against platelet aggregation and vasospasm in human coronary arteries. (1989) (36)
- Mechanism of PAF-induced platelet aggregation in man. (1986) (36)
- Artifactual-free analysis of S-nitrosoglutathione and S-nitroglutathione by neutral-pH, anion-pairing, high-performance liquid chromatography. Study on peroxynitrite-mediated S-nitration of glutathione to S-nitroglutathione under physiological conditions. (2001) (36)
- Enhanced urinary excretion of leukotriene E4 by patients with multiple trauma with or without adult respiratory distress syndrome. (1991) (36)
- Effects of a PAF-antagonist (BN 52063) on bronchoconstriction and platelet activation during exercise induced asthma. (1990) (35)
- Gas chromatographic-tandem mass spectrometric determination of acetylsalicylic acid in human plasma after oral administration of low-dose aspirin and guaimesal. (1998) (34)
- Chronic dietary supplementation with L-arginine inhibits platelet aggregation and thromboxane A2 synthesis in hypercholesterolaemic rabbits in vivo. (1998) (34)
- Enhanced synthesis of cysteinyl leukotrienes in juvenile rheumatoid arthritis. (1994) (34)
- Increased prostacyclin production during exercise in untrained and trained men: effect of low-dose aspirin. (1995) (34)
- Vascular responses to leukotriene B4, C4 and D4 following FPL 55712, indomethacin, saralasin, phentolamine and verapamil in the conscious rat (1987) (33)
- Prostacyclin in hypertension. (1990) (33)
- Dose-related effect of intravenous L-arginine on muscular blood flow of the calf in patients with peripheral vascular disease: a H215O positron emission tomography study. (1997) (32)
- Methodological considerations on the detection of 3-nitrotyrosine in the cardiovascular system. (2002) (32)
- Determination of nitric oxide metabolites by means of the Griess assay and gas chromatography–mass spectrometry in the cavernous and systemic blood of healthy males and patients with erectile dysfunction during different functional conditions of the penis (2000) (31)
- Controlled trial of high-versus low-dose aspirin treatment after percutaneous transluminal angioplasty in patients with peripheral vascular disease (1994) (31)
- Effects of chronic oral l-arginine administration on the l-arginine/NO pathway in patients with peripheral arterial occlusive disease or coronary artery disease: l-Arginine prevents renal loss of nitrite, the major NO reservoir (2015) (31)
- Enhanced synthesis of cysteinyl leukotrienes in psoriasis. (1992) (31)
- Prostaglandin endoperoxide synthetase isoenzymes: the clinical relevance of selective inhibition. (1995) (31)
- Determination of endothelium-derived nitrite/nitrate by gas chromatography/tandem mass spectrometry using (15N)NaNO2 as internal standard. (1992) (31)
- The Second Generation of COX-2 Inhibitors (2012) (31)
- Differential systemic and pulmonary hemodynamic effects of L-arginine in patients with coronary artery disease or primary pulmonary hypertension. (1996) (30)
- Gas Chromatography-Mass Spectrometry of Prostaglandins (1977) (28)
- Elevated serum nitrate concentrations in active spondyloarthropathies. (1995) (28)
- COX-2 and the kidneys. (2000) (27)
- Dose-dependent stimulation of renal prostaglandin synthesis by deamino-8-D-arginine vasopressin in rats with hereditary diabetes insipidus. (1981) (27)
- Measurement of nitrite and nitrate in plasma, serum and urine of humans by high-performance liquid chromatography, the Griess assay, chemiluminescence and gas chromatography-mass spectrometry: interferences by biogenic amines and N(G)-nitro-L-arginine analogs. (1998) (27)
- The L-arginine/NO pathway in end-stage liver disease and during orthotopic liver and kidney transplantation: biological and analytical ramifications. (2009) (27)
- Effect of captopril on prostacyclin and nitric oxide formation in healthy human subjects: interaction with low dose acetylsalicylic acid. (2003) (27)
- Effects of various nitric oxide donating agents on the contractility and cyclic nucleotide turnover of human seminal vesicles in vitro. (2002) (27)
- A simplified assay of furosemide in plasma and urine by high-pressure liquid chromatography. (1978) (27)
- High-performance liquid chromatographic analysis of nitrite and nitrate in human plasma as S-nitroso-N-acetylcysteine with ultraviolet absorbance detection. (1999) (26)
- Plasma concentrations and anti-platelet effects after low dose acetylsalicylic acid. (1985) (26)
- Differential inhibition of human platelet aggregation and thromboxane A2 formation by L-arginine in vivo and in vitro (1998) (25)
- Trouble with the analysis of nitrite, nitrate, S-nitrosothiols and 3-nitrotyrosine: freezing-induced artifacts? (2004) (25)
- Effects of carvedilol on oxidative stress in human endothelial cells and healthy volunteers (2004) (25)
- LTB4 in nephrotoxic serum nephritis in rats. (1989) (25)
- Measurement of S-nitrosoalbumin by gas chromatography-mass spectrometry. I. Preparation, purification, isolation, characterization and metabolism of S-[15N]nitrosoalbumin in human blood in vitro. (1999) (25)
- Plasma homoarginine, arginine, asymmetric dimethylarginine and total homocysteine interrelationships in rheumatoid arthritis, coronary artery disease and peripheral artery occlusion disease (2015) (24)
- Renal prostaglandins and leukotrienes. (1987) (24)
- Gas chromatographic-mass spectrometric detection of S-nitroso-cysteine and S-nitroso-glutathione. (1999) (24)
- Simultaneous GC-MS/MS measurement of malondialdehyde and 4-hydroxy-2-nonenal in human plasma: Effects of long-term L-arginine administration. (2017) (24)
- Effect of spironolactone on excretion of 3H-digoxin and its metabolites in rats. (1974) (23)
- Chronic arterial and venous catheterization of conscious, unrestrained rats. (1984) (23)
- Effects of ketoprofen and ibuprofen on platelet aggregation and prostanoid formation in man (1996) (22)
- Platelet-activating factor induces the production of leukotrienes by human monocytes. (1989) (22)
- An increase in the ratio of thromboxane A2 to prostacyclin in association with increased blood pressure in patients on cyclosporine A. (1989) (22)
- Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings (2018) (22)
- S-nitrosoalbumin plasma levels in health and disease: facts or artifacts? Value of analytical chemistry in nitric oxide clinical research. (2002) (22)
- Helicobacter pylori produces histamine and spermidine. (1996) (21)
- Metabolic disposition of prostaglandin E1 in man. (1983) (21)
- Glucocorticoid effect on arachidonic acid metabolism in vivo. (1988) (20)
- Human monocytes convert leukotriene B4 to two dihydro-leukotriene B4-metabolites. (1989) (20)
- Tandem mass spectrometric quantification of 8-iso-prostaglandin F2alpha and its metabolite 2,3-dinor-5,6-dihydro-8-iso-prostaglandin F2alpha in human urine. (2000) (19)
- Effects of Paracetamol on NOS, COX, and CYP Activity and on Oxidative Stress in Healthy Male Subjects, Rat Hepatocytes, and Recombinant NOS (2014) (19)
- Is S-nitroso-N-acetyl-L-cysteine a circulating or an excretory metabolite of nitric oxide (NO) in man? Assessment by gas chromatography-mass spectrometry. (1996) (19)
- Interaction Between Nifedipine and Atenolol: Pharmacokinetics and Pharmacodynamics in Normotensive Volunteers (1986) (17)
- Metabolism of digitoxin in man and its modification by spironolactone (1976) (17)
- Gas chromatography-mass spectrometry of cis-9,10-epoxyoctadecanoic acid (cis-EODA). II. Quantitative determination of cis-EODA in human plasma. (2004) (17)
- Urinary nitrate excretion is increased in cardiac transplanted patients with acute graft rejection. (1996) (17)
- Analysis of prostanoids by GC/MS measurement. (1982) (16)
- Gas chromatographic-tandem mass spectrometric quantification of human plasma and urinary nitrate after its reduction to nitrite and derivatization to the pentafluorobenzyl derivative. (1999) (16)
- Analysis of renal prostaglandin synthesis by competitive protein binding assay and gas chromatography--mass spectrometry. (1976) (16)
- Vascular and renal effects of leukotriene C4 in conscious rats. (1985) (16)
- [Cardiovascular effects of leukotrienes]. (1989) (16)
- Elevated urinary excretion of nitric oxide metabolites in young infants with Zellweger syndrome. (2003) (15)
- Effects of normalization of plasma testosterone levels in hypogonadal men on plasma levels and urinary excretion of asymmetric dimethylarginine (ADMA). (2008) (14)
- Measurement of icosanoids. Report of the Group for Standardization of Methods in Icosanoid Research. (1984) (14)
- Dietary L-arginine normalizes endothelin-induced vascular contractions in cholesterol-fed rabbits. (1998) (14)
- A competitive protein binding assay specific for prostaglandin E. (1974) (14)
- [Incidence and prevention of lethal undesirable drug effects]. (2003) (14)
- No effects of atorvastatin (10 mg/d or 80 mg/d) on nitric oxide, prostacyclin, thromboxane and oxidative stress in type 2 diabetes mellitus patients of the DALI study. (2015) (13)
- Gas chromatography-mass spectrometry of cis-9,10-epoxyoctadecanoic acid (cis-EODA). I. Direct evidence for cis-EODA formation from oleic acid oxidation by liver microsomes and isolated hepatocytes. (2003) (13)
- Are prostaglandins involved in the antihypertensive effect of dihydralazine? (1981) (13)
- Falsely elevated digoxin concentrations in patients with liver disease. (1985) (13)
- Methods in prostaglandin research (1978) (13)
- Urinary prostaglandin and kallikrein excretion are not flow dependent in the rat. (1983) (13)
- Formation of S-nitroso compounds from sodium nitroprusside, nitric oxide or nitrite and reduced thiols: analysis by capillary isotachophoresis (1995) (13)
- Bioassay of a tracheal smooth muscle-constricting factor released by respiratory epithelial cells. (1992) (12)
- Acute effects of antidiuretic hormone on urinary prostaglandin excretion. (1983) (12)
- Mechanism of antihypertensive action of ketanserin in man (1983) (12)
- Gas chromatographic-mass spectrometric discrimination between 8-iso-prostaglandin E2 and prostaglandin E2 through derivatization by O-(2,3,4,5,6-Pentafluorobenzyl)hydroxyl amine. (1998) (12)
- Renal vascular effects of leukotriene C4 in the isolated perfused kidney of the rat (1987) (11)
- Study of the effects of cicletanine on prostanoids. (1985) (11)
- Solid- and liquid-phase extraction for the gas chromatographic-tandem mass spectrometric quantification of 2,3-dinor-thromboxane B2 and 2,3-dinor-6-oxo-prostaglandin F1 alpha in human urine. (2000) (11)
- Central and autonomic nervous system side effects of ketanserin. (1986) (11)
- Aortic thrombus and pulmonary embolism in a patient with hyperhomocysteinemia (2006) (11)
- Catalytic hydrogenation of leukotriene B4 enhances sensitivity and specificity of gas chromatography-tandem mass spectrometry techniques and enables simultaneous analysis with cysteinyl leukotrienes in biological fluids. (1996) (11)
- Impaired Degradation of Prostaglandins and Thromboxane in Zellweger Syndrome (1994) (11)
- Is circulating nitrite a directly acting vasodilator? (2002) (11)
- Plasma levels of sulfinpyrazone and of two of its metabolites after a single dose and during the steady state (2004) (10)
- Gas chromatographic-mass spectrometric determination of leukotriene E4 in human urine using deuterium-labelled leukotriene E4 standards. (1993) (10)
- Effects of Nonsteroidal Phospholipase Inhibitors and Glucocorticoids on Endothelium‐Dependent Relaxations of Rabbit Aorta Induced by Different Agents (1987) (10)
- Cardiac and microcirculatory effects of different doses of prostaglandin E1 in man (2004) (10)
- Analysis of leukotrienes, prostaglandins, thromboxane B2 and their metabolites by capillary isotachophoresis (1993) (10)
- Measurement and diagnostic use of hepatic cytochrome P450 metabolism of oleic acid in liver disease (2010) (10)
- Analysis of prostanoid metabolites by gas chromatography/mass spectrometry. (1985) (9)
- [Transcutaneous pO2 and laser Doppler flux in increasing doses of intraarterial and intravenously administered prostaglandin E1]. (1987) (9)
- Effects of intravenous oxygen on prostacyclin and thromboxane formation in patients with peripheral occlusive arterial disease. (2001) (9)
- Problems of assessment of prostacyclin formation in vivo. (1984) (9)
- Effects of dietary variation in linoleic acid content on the major urinary metabolites of the E prostaglandins (PGE-M) in infants. (1980) (9)
- Role of AVP in malignant DOC-salt hypertension: studies using vascular and antidiuretic antagonists. (1987) (9)
- Influence of intravenous acetylsalicylic acid and sodium salicylate on human renal function and lithium clearance (2004) (9)
- The effects of metamizol on prostaglandin synthesis in man. (1986) (9)
- Increased total body synthesis of prostacyclin in rats with adjuvant arthritis. (1995) (9)
- Determination, source, metabolism, and functional role of renal prostaglandins. (1980) (9)
- IS KETANSERIN A D RECEPTOR ANTAGONIST? (1983) (9)
- Effect of aprotinin on the renal response to vasopressin in diabetes insipidus rats. (1983) (9)
- Effect of vasopressin blockade on blood pressure in conscious rats with malignant two-kidney Goldblatt hypertension. (1985) (9)
- Is S‐nitrosoglutathione formed in nitric oxide synthase incubates? (2000) (9)
- The binding of prostaglandins to rat liver plasma membranes and its use in the assay of urinary prostaglandins. (1974) (9)
- NSAID: can renal side effects be avoided? (1996) (8)
- Role of eicosanoids in regulation of vascular resistance. (1989) (8)
- Blood donors on medication. Are deferral periods necessary? (2001) (8)
- Identification of the major metabolite of prostacyclin and 6-ketoprostaglandin F1 alpha in man. (1980) (8)
- Determination of chloride in biological fluids as pentafluorobenzylchloride by reversed-phase high-performance liquid chromatography and UV detection (1992) (8)
- INFLUENCE OF PROSTAGLANDIN INHIBITION ON DIHYDRALAZINE INDUCED ACUTE EFFECTS IN PATIENTS WITH ESSENTIAL HYPERTENSION * (1985) (8)
- [Dose-dependent side effects of acetylsalicylic acid therapy. Results of a prospective randomized clinical study in patients with peripheral arterial occlusive disease]. (1993) (8)
- Enzymic preparation of dioxygen-18 labelled leukotriene E4 and its use in quantitative gas chromatography-mass spectrometry. (1992) (8)
- Characterization of prostaglandin E receptor in membranes and its use in the assay of prostaglandin E. (1974) (7)
- Evidence against a vasopressor role of ADH in malignant DOC-salt hypertension. (1985) (7)
- Enzyme-immunoassay of thromboxane B2 at the picogram level. (1985) (7)
- "Monitors" and European Community guideline on clinical trials (1991) (6)
- Thimerosal induces endothelium-dependent vascular smooth muscle relaxations by interacting with thiol groups (1986) (6)
- Drug expenditure in hospitals: what do German ward physicians know? (2001) (6)
- Measurements of urinary kinins by HPLC-radioimmunoassay. (1984) (6)
- Assessment of cysteinyl leukotriene synthesis in man. (1994) (6)
- Variability in the pharmacokinetics of atenolol and metoprolol. (1985) (6)
- Enzymatic and chemical labelling of prostaglandin E1 and 13,14-dihydro-15-keto-prostaglandin E1 (1993) (6)
- Differential effects of two calcium channel blockers on bronchial smooth muscle. (1995) (5)
- Effects of chronic oral l-arginine administration on the l-arginine/NO pathway in patients with peripheral arterial occlusive disease or coronary artery disease: l-Arginine prevents renal loss of nitrite, the major NO reservoir (2015) (5)
- Chemical synthesis of dioxygen-18 labelled ω-/β-oxidized cysteinyl leukotrienes: analysis by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry (1995) (5)
- Thimerosal, an inhibitor of endothelial acyl-coenzyme A: lysolecithin acyltransferase, stimulates the production of a nonprostanoid endothelium-derived vascular relaxing factor. (1987) (5)
- [Pathogenetic aspects of the L-arginine-NO metabolic pathway in arteriosclerosis and possible therapeutic aspects]. (1996) (5)
- The importance of renal prostaglandin synthesis in maintaining renal blood flow and glomerular filtration after renal artery stenosis in the conscious dog. (1978) (5)
- Enzymatic synthesis of dioxygen‐18 labelled 8‐epi‐prostanglandin F2α and its use in quantitative GC‐tandem MS (1997) (4)
- Capillary isotachophoretic determination of cysteinyl leukotrienes. (1991) (4)
- Analysis of prostacyclin (1984) (4)
- Prostaglandins: role in renin regulation and mediation of antihypertensive drug effects. (1980) (4)
- Interference by S-nitroso compounds with the measurement of nitrate in methods requiring reduction of nitrate to nitrite by cadmium. (1999) (4)
- Renal side effects of NSAIDs: role of COX-1 and COX-2 (1998) (4)
- Advances in the analysis of eicosanoids by ELISA and GC/MS/MS. (1986) (4)
- Investigations on Renal Prostaglandins by Gas Chromatography—Mass Spectrometry (1983) (3)
- Unusual collision-induced dissociation of fluorated and non-fluorated alpha-nitrotoluene analogs in a gas chromatograph triple-stage quadrupole mass spectrometer under electron-capturing negative-ion chemical ionization conditions. (2005) (3)
- Quantitative determination of prostaglandins. (1973) (3)
- Determination of nitrite as pentafluorobenzyl derivative by RP-HPLC and UV detection with and without ion-pair extraction (1992) (3)
- Differential effects of deamino-8-D-arginine vasopressin on urinary prostaglandins E2 and F2 alpha excretion. (1980) (3)
- DDAH activity is not associated with oxidative stress in elderly patients with peripheral arterial occlusive disease (2014) (3)
- Synthesis of nitric oxide releasing, vasodilating and platelet aggregation inhibiting S‐[15N]nitroso compounds (1994) (3)
- [Vipoma. 9-year observations using currently available therapy methods]. (2008) (3)
- In vitro effects of a novel class of no donating compounds on isolated human erectile tissue (2002) (3)
- Biosynthesis of homoarginine (hArg) and asymmetric dimethylarginine (ADMA) from acutely and chronically administered free l-arginine in humans (2015) (3)
- Nitric oxide synthesis in chronic renal failure. Are plasma S-nitrosothiol levels elevated? (2004) (3)
- [The effect of bronchial epithelium on bronchial contractility]. (1990) (3)
- Prostaglandins in Human Hypertension: Relationships to Renin, Sodium, and Antihypertensive Drug Action (1981) (3)
- ANALYSIS OF EICOSANOIDS BY GC-MS/MS (1988) (3)
- Blood donors on medication (2001) (3)
- Relevance of urinary 6-keto-prostaglandin F1 alpha determination. (1981) (3)
- Effects of intravenous aspirin on prostaglandin synthesis and kidney function in intensive care patients. (1986) (3)
- Role of icosanoids in regulation of blood pressure. (1985) (3)
- Metabolism of peruvoside in man (1972) (3)
- Platelet aggregation, sensitivity to prostaglandin E1 and thromboxane A2 release in recombinant hirudin- and heparin-anticoagulated blood. (1996) (2)
- Analysis of Prostanoids and their Metabolites by Gas Chromatography-Mass Spectrometry (1980) (2)
- Cardiovascular effects of leukotrienes (2005) (2)
- Pregraduate teaching clinical pharmacology in Germany (2004) (2)
- Analysis of nitrite and nitrate as 1-nitro-2,4,6-trimethoxybenzene derivatives by reversed-phase HPLC with UV-detection (1992) (2)
- Metabolism of prostacyclin and 6-keto-prostaglandin F1 alpha in man. (1980) (2)
- Consensus conferences : impact on clinical prescribing habits (1995) (2)
- [New non-steroidal anti-rheumatic drugs: selective inhibitors of inducible cyclooxygenase]. (1998) (2)
- Analysis of cysteinyl leukotrienes and leukotriene B4 by gas chromatography-(tandem) mass spectrometry. (1992) (2)
- Education in clinical pharmacology (1994) (2)
- [Therapy with preferential and specific COX-2 inhibitors]. (2001) (2)
- Renal prostaglandins (1982) (2)
- Antihypertensive inorganic nitrate and nitrite: what is the underlying mechanism? (2013) (2)
- Knowledge on drug dosages of ward physicians (2002) (2)
- [Comparison of 50 mg and 900 mg/day acetylsalicylic acid for prevention of recurrence after percutaneous transluminal angioplasty of the lower extremities: results of the LARA study]. (1992) (2)
- Synthesis of [14,15,17,17,18,18‐2H6]‐leukotriene B4 (1992) (2)
- [Is there an improvement of drug safety in Germany in recent years?]. (2009) (2)
- Urinary and systemic metabolites of prostacyclin in the perfused rabbit kidney. (1982) (1)
- [Effects of intravenous prostaglandin E1 on bronchial histamine reactivity]. (1990) (1)
- A new bioassay to study contractile and relaxant effects of PGE2 on perfused guinea pig trachea. (1996) (1)
- Effect of Lovastatin on Plaque Formation and Ldl Oxidation in Cholesterol-Fed Rabbits (1998) (1)
- Comments from chairs of institutes of clinical pharmacology in Germany. (1994) (1)
- Analysis of leukotriene B4 as free acid and its δ-lactone by high-performance liquid chromatography: a study on the stability and formation of leukotriene B4 δ-lactone (1993) (1)
- Nitrosative stress does not change during orthotopic liver transplantation (2014) (1)
- [The effect of indomethacin and carprofen on gastric prostaglandin biosynthesis]. (1984) (1)
- [Role of prostaglandins in the regulation of renin (author's transl)]. (1981) (1)
- Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings (2018) (1)
- [Sonographic objectivation of cheek swelling following perioperative edema prevention using dexamethasone during third molar osteotomies]. (1988) (1)
- [Intravenous immunoglobulins. Basic principles, selection criteria and indications for preventive and therapeutic administration]. (1995) (1)
- [Combined analgetic drug treatment with ibuprofen after 3rd molar osteotomy]. (1990) (1)
- [Medication errors. Cause of death for every 100th hospital patient? (interview by Dr. Thomas Meissner)]. (2003) (1)
- [Aspirin--yes, but 30 mg??]. (1995) (0)
- [Omega-3-fatty acids. Do they help with depression?]. (2012) (0)
- [Anti-arteriosclerosis effects due to stimulation of endogenous nitric oxide synthesis]. (1997) (0)
- Endothelial Cyclic Nucleotides are Unlikely to Regulate EDRF Release (1991) (0)
- L-arginine and analogs as inhibitors of thrombocyte aggregation. (1994) (0)
- [Legal liability in drug trials]. (1995) (0)
- The kallikrein-kinin system in circulatory and metabolic homeostasis (1981) (0)
- Careers in pharmacology: the German perspective (1996) (0)
- 1 Results , meta-analysis and a first evaluation of U NOx R , the urinary nitrate-to-nitrite molar ratio , as a measure of nitrite reabsorption in experimental and clinical settings (2019) (0)
- [Therapeutic drug monitoring in general practice--indications and interpretation]. (1993) (0)
- Importance of Prostanoids for Bronchial Smooth Muscle Tone (1993) (0)
- [Positive lists/negative lists from the viewpoint of clinical pharmacology]. (1997) (0)
- [Volume replacement therapy with human albumin. Basic principles, differential indications, alternatives]. (1993) (0)
- [The 1982 Nobel Prize in medicine: prostaglandins]. (1982) (0)
- [Magnesium is no longer effective: calf cramps are becoming more severe]. (2012) (0)
- [Can ezetimib also be used as a treatment for beta-sitosterol]. (2004) (0)
- [Fear of dependency and habituation. Prejudices and an obstacle to NSAID treatment]. (2005) (0)
- Effect of synthetic leikotriene C4 (LTC4) on renal electrolyte excretion in the conscious rat (1984) (0)
- [Prostacyclin in hypertension]. (1992) (0)
- Pharmacodynamic Interactions between Nifedipine and Atenolol (1985) (0)
- Different antioxidant mechanisms of α-tocopherol and L-arginine result in preserved endothelial function in hypercholesterolaemic rabbits. (1999) (0)
- PAF-induced platelet aggregation and TXB2 formation. (1989) (0)
- [Ginseng. Does it really help?]. (2013) (0)
- Plasma homoarginine, arginine, asymmetric dimethylarginine and total homocysteine interrelationships in rheumatoid arthritis, coronary artery disease and peripheral artery occlusion disease (2015) (0)
- [Adverse drug effects: 10,000 preventable fatalities per year?. Interview by Dr. Stephanie Czajka]. (1999) (0)
- 713-4 Inhibition of Vascular Superoxide Production in Hypercholesterolemic Rabbit Aorta by L-Arginine Contributes to Restored Endothelium-dependent Relaxation (1995) (0)
- Comment on Jüni P, Dieppe P. Older people should NOT be prescribed 'coxibs' in place of conventional NSAIDs. (2004) (0)
- Chemical synthesis of dioxygen-18 labelled omega-/beta-oxidized cysteinyl leukotrienes: analysis by gas chromatography-mass spectrometry and gas chromatography-tandem mass spectrometry. (1995) (0)
- Effects of sulfinpyrazone on renal function and prostaglandin formation in man. (1985) (0)
- Proceedings: The influence of spironolactone on the excretion and metabolism of 3H-digoxin in the rat. (1974) (0)
- [Unwanted effects of therapeutic drugs on the structure and function of the lung from a clinico-pharmacologic viewpoint]. (1990) (0)
- Interaction of ADH renal prostaglandins in the regulation of salt and water excretion (1984) (0)
- [Special therapeutic processes from the viewpoint of clinical pharmacology]. (1997) (0)
- [Comments on the contribution by Prof. Dr. S. H. Hohnloser. Sotalol]. (1995) (0)
- of Analytical Chemistry in Nitric Oxide Clinical Research -Nitrosoalbumin Plasma Levels in Health and Disease: Facts or Artifacts? Value S (2011) (0)
- [What significance has the C(2) value in the treatment with cyclosporin A?]. (2004) (0)
- [Risks of simultaneous tocolytic treatment with beta adrenergic and PG inhibiting agents]. (1981) (0)
- Cardiovascular System Methodological Considerations on the Detection of 3-Nitrotyrosine in the (2012) (0)
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What Schools Are Affiliated With Jürgen C. Frölich?
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