Juri Rappsilber

Q: What Schools Are Affiliated With Juri Rappsilber

Juri Rappsilber is affiliated with the following schools: University of Southern Denmark, University of Verona, University of Edinburgh, University of Tübingen, Kyoto University, Technical University of Berlin

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Juri Rappsilber

Chemistry

#2355

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#3252

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chemistry Degrees

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Chemistry

Juri Rappsilber's Degrees

PhD Chemistry University of Southern Denmark

Why Is Juri Rappsilber Influential?

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According to Wikipedia, Juri Rappsilber is a German chemist in the area of mass spectrometry and proteomics. Career Rappsilber studied chemistry at the Technical University of Berlin, University of Strathclyde, and with Tom Rapoport, Harvard Medical School. In 2001, he earned his Ph.D. in Proteomics jointly from EMBL Heidelberg and the Goethe University Frankfurt working in the laboratory of Matthias Mann on the mass spectrometric analysis of protein complexes, externally supervised by Michael Karas. He followed Mann to the University of Southern Denmark and completed a postdoctoral fellowship before starting his independent career at IFOM - FIRC Institute for Molecular Oncology, Milan in 2003. In 2006, he joined the Wellcome Trust Centre for Cell Biology in the Institute of Cell Biology at the University of Edinburgh. In 2009, he became a senior research fellow of the Wellcome Trust, in 2010 he was appointed Professor of Proteomics in Edinburgh. Since 2011, he has been Full Professor and head of the Chair of Bioanalytics at the Technical University of Berlin.

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Juri Rappsilber's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips (2007) (3277)
Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. (2003) (2261)
Exponentially Modified Protein Abundance Index (emPAI) for Estimation of Absolute Protein Amount in Proteomics by the Number of Sequenced Peptides per Protein*S (2005) (1925)
UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development (2007) (1234)
miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs. (2002) (1152)
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity (2011) (960)
Large-scale proteomic analysis of the human spliceosome. (2002) (917)
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3 (2006) (732)
A model for transmission of the H3K27me3 epigenetic mark (2008) (628)
BoxPlotR: a web tool for generation of box plots (2014) (581)
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells (2010) (579)
RBP2 Belongs to a Family of Demethylases, Specific for Tri-and Dimethylated Lysine 4 on Histone 3 (2007) (535)
Implications for Kinetochore-Microtubule Attachment from the Structure of an Engineered Ndc80 Complex (2008) (516)
Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex (1998) (483)
Protein abundance profiling of the Escherichia coli cytosol (2008) (470)
Architecture of the RNA polymerase II–TFIIF complex revealed by cross-linking and mass spectrometry (2010) (399)
The beginning of a beautiful friendship: Cross-linking/mass spectrometry and modelling of proteins and multi-protein complexes (2011) (397)
The Methylosome, a 20S Complex Containing JBP1 and pICln, Produces Dimethylarginine-Modified Sm Proteins (2001) (389)
Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly (2001) (382)
Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor (2013) (317)
Phosphodependent Recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 Kinase Maintains the Spindle Checkpoint (2012) (291)
Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components (2014) (289)
The Protein Composition of Mitotic Chromosomes Determined Using Multiclassifier Combinatorial Proteomics (2010) (285)
Microcolumns with self-assembled particle frits for proteomics. (2002) (282)
Modular stop and go extraction tips with stacked disks for parallel and multidimensional Peptide fractionation in proteomics. (2006) (282)
eIF4A3 is a novel component of the exon junction complex. (2004) (240)
Structural Analysis of Multiprotein Complexes by Cross-linking, Mass Spectrometry, and Database Searching*S (2007) (237)
A Functional Interaction between the Survival Motor Neuron Complex and RNA Polymerase II (2001) (235)
The NOT proteins are part of the CCR4 transcriptional complex and affect gene expression both positively and negatively (1998) (231)
Exploring the hidden human urinary proteome via ligand library beads. (2005) (229)
A Novel WD Repeat Protein Component of the Methylosome Binds Sm Proteins* (2002) (224)
A novel complex of membrane proteins required for formation of a spherical nucleus (1998) (210)
Stc1: A Critical Link between RNAi and Chromatin Modification Required for Heterochromatin Integrity (2010) (209)
xiNET: Cross-link Network Maps With Residue Resolution* (2015) (207)
Fission Yeast Scm3: A CENP-A Receptor Required for Integrity of Subkinetochore Chromatin (2009) (202)
Bypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A‐ARF locus (2007) (200)
A generic strategy to analyze the spatial organization of multi-protein complexes by cross-linking and mass spectrometry. (2000) (192)
A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation (2010) (191)
Repo-Man Coordinates Chromosomal Reorganization with Nuclear Envelope Reassembly during Mitotic Exit (2011) (180)
Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology (2018) (177)
What does it mean to identify a protein in proteomics? (2002) (168)
Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop. (2015) (163)
REST–Mediated Recruitment of Polycomb Repressor Complexes in Mammalian Cells (2012) (163)
Gemin5, a Novel WD Repeat Protein Component of the SMN Complex That Binds Sm Proteins* (2002) (163)
Detection of arginine dimethylated peptides by parallel precursor ion scanning mass spectrometry in positive ion mode. (2003) (161)
Proteomic analysis of human blood serum using peptide library beads. (2007) (158)
Purification of Native Survival of Motor Neurons Complexes and Identification of Gemin6 as a Novel Component* (2002) (152)
Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex. (2001) (150)
Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα (2012) (143)
Quantitative cross-linking/mass spectrometry using isotope-labelled cross-linkers☆ (2013) (142)
Multiple molecular architectures of the eye lens chaperone αB-crystallin elucidated by a triple hybrid approach (2011) (138)
Spot overlapping in two‐dimensional maps: A serious problem ignored for much too long (2005) (136)
Tissue-specific control of brain-enriched miR-7 biogenesis. (2013) (135)
In-cell architecture of an actively transcribing-translating expressome (2020) (126)
Identification and Characterization of Gemin7, a Novel Component of the Survival of Motor Neuron Complex* (2002) (125)
Splicing Factors Facilitate RNAi-Directed Silencing in Fission Yeast (2008) (124)
Arginine methylation of Aubergine mediates Tudor binding and germ plasm localization. (2010) (118)
Quirks of Error Estimation in Cross-Linking/Mass Spectrometry (2017) (113)
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination (2017) (110)
Gemin8 Is a Novel Component of the Survival Motor Neuron Complex and Functions in Small Nuclear Ribonucleoprotein Assembly* (2006) (108)
Structural basis of MCM2-7 replicative helicase loading by ORC-Cdc6 and Cdt1 (2017) (107)
G9a/GLP Complex Maintains Imprinted DNA Methylation in Embryonic Stem Cells (2016) (103)
A folded conformation of MukBEF and cohesin (2018) (101)
A model for transmission of the H3K27me3 epigenetic mark (2008) (98)
A novel in vitro metabolomics approach for neurotoxicity testing, proof of principle for methyl mercury chloride and caffeine. (2008) (97)
A Yeast Exosome Cofactor, Mpp6, Functions in RNA Surveillance and in the Degradation of Noncoding RNA Transcripts (2008) (95)
Capturing protein communities by structural proteomics in a thermophilic eukaryote (2017) (91)
Structural basis for microtubule recognition by the human kinetochore Ska complex (2014) (87)
Arginine Methylation of Vasa Protein Is Conserved across Phyla* (2010) (87)
Rio1 mediates ATP-dependent final maturation of 40S ribosomal subunits (2014) (87)
Unrip is a component of SMN complexes active in snRNP assembly (2005) (86)
Self‐made frits for nanoscale columns in proteomics (2005) (85)
A Structure-Based Mechanism for DNA Entry into the Cohesin Ring (2020) (85)
Structure of hibernating ribosomes studied by cryoelectron tomography in vitro and in situ (2010) (85)
Co-regulation map of the human proteome enables identification of protein functions (2019) (82)
Cohesin-Dependent Association of Scc2/4 with the Centromere Initiates Pericentromeric Cohesion Establishment (2013) (81)
First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study (2019) (80)
Trim25 Is an RNA-Specific Activator of Lin28a/TuT4-Mediated Uridylation (2014) (80)
Gain of function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions (2018) (80)
An integrated workflow for crosslinking mass spectrometry (2019) (76)
When less can yield more – Computational preprocessing of MS/MS spectra for peptide identification (2009) (75)
SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication (2016) (75)
Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere (2014) (74)
Sister kinetochores are mechanically fused during meiosis I in yeast (2014) (73)
A Genetic Engineering Solution to the “Arginine Conversion Problem” in Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC) (2010) (72)
The Histone Lysine Demethylase JMJD3/KDM6B Is Recruited to p53 Bound Promoters and Enhancer Elements in a p53 Dependent Manner (2014) (71)
SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation (2020) (70)
Serum Albumin Domain Structures in Human Blood Serum by Mass Spectrometry and Computational Biology* (2015) (70)
Chromatin enrichment for proteomics (2014) (70)
Cytoplasmic TAF2–TAF8–TAF10 complex provides evidence for nuclear holo–TFIID assembly from preformed submodules (2015) (70)
Pervasive coexpression of spatially proximal genes is buffered at the protein level (2017) (69)
A Single α Helix Drives Extensive Remodeling of the Proteasome Lid and Completion of Regulatory Particle Assembly (2015) (69)
Microtubule Nucleation Properties of Single Human γTuRCs Explained by Their Cryo-EM Structure (2020) (68)
Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism (2020) (66)
Rrp5 Binding at Multiple Sites Coordinates Pre-rRNA Processing and Assembly (2013) (66)
Defining the RNA interactome by total RNA‐associated protein purification (2019) (66)
Protein Tertiary Structure by Crosslinking/Mass Spectrometry (2018) (66)
Structure of the Fanconi anemia monoubiquitin ligase complex (2019) (66)
FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair (2020) (65)
A Study into the Collision-induced Dissociation (CID) Behavior of Cross-Linked Peptides* (2015) (65)
Molecular and genetic analysis of condensin function in vertebrate cells. (2008) (64)
Drosophila Syncrip binds the gurken mRNA localisation signal and regulates localised transcripts during axis specification (2012) (61)
Model for stathmin/OP18 binding to tubulin (2000) (61)
Chemical Evolution of a Bacterial Proteome. (2015) (60)
Complement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from Complement (2015) (60)
Experiences and perspectives of MALDI MS and MS/MS in proteomic research (2003) (59)
Direct interaction of actin filaments with F‐BAR protein pacsin2 (2014) (57)
Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation (2019) (56)
Lin28a regulates neuronal differentiation and controls miR-9 production (2014) (56)
Improved results in proteomics by use of local and peptide-class specific false discovery rates (2009) (53)
Three-dimensional topology of the SMC2/SMC4 subcomplex from chicken condensin I revealed by cross-linking and molecular modelling (2015) (53)
Proteomics of a fuzzy organelle: interphase chromatin (2014) (53)
Prdm5 Regulates Collagen Gene Transcription by Association with RNA Polymerase II in Developing Bone (2012) (53)
Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control (2015) (53)
Genetic code expansion for multiprotein complex engineering (2016) (53)
Dynamics of Ribosomal Protein S1 on a Bacterial Ribosome with Cross-Linking and Mass Spectrometry* (2012) (52)
Pom1 regulates the assembly of Cdr2–Mid1 cortical nodes for robust spatial control of cytokinesis (2014) (52)
Nop9 is an RNA binding protein present in pre-40S ribosomes and required for 18S rRNA synthesis in yeast. (2007) (52)
CENP-A confers a reduction in height on octameric nucleosomes (2013) (51)
A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion (2016) (51)
Structure of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling* (2016) (50)
SPF30 Is an Essential Human Splicing Factor Required for Assembly of the U4/U5/U6 Tri-small Nuclear Ribonucleoprotein into the Spliceosome* (2001) (49)
Optimizing the Parameters Governing the Fragmentation of Cross-Linked Peptides in a Tribrid Mass Spectrometer (2017) (49)
Proteomic profiling of PrP27‐30‐enriched preparations extracted from the brain of hamsters with experimental scrapie (2009) (48)
The mzIdentML Data Standard Version 1.2, Supporting Advances in Proteome Informatics* (2017) (48)
Kinase Activity of Fission Yeast Mph1 Is Required for Mad2 and Mad3 to Stably Bind the Anaphase Promoting Complex (2012) (46)
xiView: A common platform for the downstream analysis of Crosslinking Mass Spectrometry data (2019) (45)
Quantitative cross-linking/mass spectrometry to elucidate structural changes in proteins and their complexes (2018) (45)
Repo-Man/PP1 regulates heterochromatin formation in interphase (2017) (44)
Reliable identification of protein-protein interactions by crosslinking mass spectrometry (2020) (44)
Building mitotic chromosomes (2011) (43)
Whole-proteome genetic analysis of dependencies in assembly of a vertebrate kinetochore (2015) (42)
Protein Dynamics in Solution by Quantitative Crosslinking/Mass Spectrometry (2018) (41)
Mechanism for Aar2p function as a U5 snRNP assembly factor. (2011) (40)
Pre-40S ribosome biogenesis factor Tsr1 is an inactive structural mimic of translational GTPases (2016) (40)
In Situ Structural Restraints from Cross-Linking Mass Spectrometry in Human Mitochondria (2019) (40)
Explorer TET 1 and hydroxymethylcytosine in transcription and DNA methylation fidelity (2012) (39)
The structure of human thyroglobulin (2020) (38)
Understudied proteins: opportunities and challenges for functional proteomics (2022) (38)
Eic1 links Mis18 with the CCAN/Mis6/Ctf19 complex to promote CENP-A assembly (2014) (38)
On the Reproducibility of Label-Free Quantitative Cross-Linking/Mass Spectrometry (2017) (38)
Ska3 Ensures Timely Mitotic Progression by Interacting Directly With Microtubules and Ska1 Microtubule Binding Domain (2016) (37)
A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis (2019) (36)
Defining the RNA Interactome by Total RNA-Associated Protein Purification (2018) (35)
Comprehensive identification of proteins binding to RNA G-quadruplex motifs in the 5' UTR of tumor-associated mRNAs. (2018) (35)
Stress-Induced Translation Inhibition through Rapid Displacement of Scanning Initiation Factors (2020) (34)
Tumor suppressor ASXL1 is essential for the activation of INK4B expression in response to oncogene activity and anti-proliferative signals (2015) (34)
The Mitosis and Neurodevelopment Proteins NDE1 and NDEL1 Form Dimers, Tetramers, and Polymers with a Folded Back Structure in Solution* (2012) (34)
14-3-3 regulation of Ncd reveals a new mechanism for targeting proteins to the spindle in oocytes (2017) (34)
In-Search Assignment of Monoisotopic Peaks Improves the Identification of Cross-Linked Peptides (2018) (33)
Quantitative Cross-linking/Mass Spectrometry Using Isotope-labeled Cross-linkers and MaxQuant* (2016) (32)
Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes (2016) (32)
Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination (2021) (32)
Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity (2019) (32)
Purified Smc5/6 Complex Exhibits DNA Substrate Recognition and Compaction (2020) (31)
TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing (2020) (31)
xiSPEC: web-based visualization, analysis and sharing of proteomics data (2018) (31)
Silencing Mediated by the Schizosaccharomyces pombe HIRA Complex Is Dependent upon the Hpc2-Like Protein, Hip4 (2010) (30)
The structure and oxidation of the eye lens chaperone αA-crystallin (2019) (30)
Transposon‐driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution (2017) (30)
An integrated workflow for cross-linking/mass spectrometry (2018) (29)
Anatomy of a crosslinker. (2020) (29)
Borealin–nucleosome interaction secures chromosome association of the chromosomal passenger complex (2019) (29)
Optimized Fragmentation Regime for Diazirine Photo-Cross-Linked Peptides (2016) (28)
Endogenous Mouse Dicer Is an Exclusively Cytoplasmic Protein (2016) (28)
Federating Structural Models and Data: Outcomes from A Workshop on Archiving Integrative Structures. (2019) (27)
Labile sulfogroup allows differentiation of sulfotyrosine and phosphotyrosine in peptides. (2001) (27)
Raf1 Is a DCAF for the Rik1 DDB1-Like Protein and Has Separable Roles in siRNA Generation and Chromatin Modification (2012) (27)
Blind testing of cross‐linking/mass spectrometry hybrid methods in CASP11 (2016) (27)
Molecular interactions between Hel2 and RNA supporting ribosome-associated quality control (2019) (26)
Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID (2017) (26)
Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes (2021) (26)
Molecular architecture of the Dam1 complex–microtubule interaction (2016) (26)
The IntAct database: efficient access to fine-grained molecular interaction data (2021) (25)
Proteomics Analysis with a Nano Random Forest Approach Reveals Novel Functional Interactions Regulated by SMC Complexes on Mitotic Chromosomes* (2016) (25)
Cell Cycle Regulation of Microtubule Interactomes: Multi-layered Regulation Is Critical for the Interphase/Mitosis Transition* (2013) (25)
Mto2 multisite phosphorylation inactivates non-spindle microtubule nucleation complexes during mitosis (2015) (25)
Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry. (2020) (25)
Integrative structure of a 10-megadalton eukaryotic pyruvate dehydrogenase complex from native cell extracts. (2021) (25)
Proteomic analysis of pancreatic ductal carcinoma cells after combined treatment with gemcitabine and trichostatin A. (2005) (24)
Fission Yeast NDR/LATS Kinase Orb6 Regulates Exocytosis via Phosphorylation of the Exocyst Complex (2019) (24)
Assessment of chemical‐crosslink‐assisted protein structure modeling in CASP13 (2019) (23)
A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast (2014) (23)
The δ subunit and NTPase HelD institute a two-pronged mechanism for RNA polymerase recycling (2020) (23)
Small angle X‐ray scattering and cross‐linking for data assisted protein structure prediction in CASP 12 with prospects for improved accuracy (2018) (23)
Proteomics Using Protease Alternatives to Trypsin Benefits from Sequential Digestion with Trypsin (2020) (22)
Blind Evaluation of Hybrid Protein Structure Analysis Methods based on Cross-Linking (2016) (22)
Proteome Analysis of Human Neutrophil Granulocytes From Patients With Monogenic Disease Using Data-independent Acquisition* (2019) (22)
Multiple RNA interactions position Mrd1 at the site of the small subunit pseudoknot within the 90S pre-ribosome (2012) (21)
Auxin/AID versus conventional knockouts: distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability (2016) (21)
DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network (2021) (21)
Visualizing translation dynamics at atomic detail inside a bacterial cell (2021) (20)
Cross-linking mass spectrometry identifies new interfaces of Augmin required to localise the γ-tubulin ring complex to the mitotic spindle (2017) (20)
Proteomics of isolated mitotic chromosomes identifies the kinetochore protein Ska3/Rama1. (2010) (20)
Genes Important for Schizosaccharomyces pombe Meiosis Identified Through a Functional Genomics Screen (2017) (20)
The kinetochore module Okp1CENP‐Q/Ame1CENP‐U is a reader for N‐terminal modifications on the centromeric histone Cse4CENP‐A (2018) (20)
Reductional Meiosis I Chromosome Segregation Is Established by Coordination of Key Meiotic Kinases (2019) (20)
Sequential Digestion with Trypsin and Elastase in Cross-Linking Mass Spectrometry (2018) (20)
Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1 (2019) (19)
The Arabidopsis epigenetic regulator ICU11 as an accessory protein of Polycomb Repressive Complex 2 (2020) (19)
Shulin packages axonemal outer dynein arms for ciliary targeting (2020) (19)
Posttranscriptional Regulation of 14q32 MicroRNAs by the CIRBP and HADHB during Vascular Regeneration after Ischemia (2018) (19)
Complementary Benzophenone Cross-Linking/Mass Spectrometry Photochemistry (2017) (18)
Leveraging crosslinking mass spectrometry in structural and cell biology. (2021) (18)
Heterologous Biosynthesis, Modifications and Structural Characterization of Ruminococcin-A, a Lanthipeptide From the Gut Bacterium Ruminococcus gnavus E1, in Escherichia coli (2018) (18)
Structural basis for centromere maintenance by Drosophila CENP‐A chaperone CAL1 (2020) (17)
Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP (2016) (17)
Substrate specificity of the TRAMP nuclear surveillance complexes (2020) (17)
Quantitative Photo-crosslinking Mass Spectrometry Revealing Protein Structure Response to Environmental Changes (2019) (17)
RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit (2017) (16)
Noncovalently Associated Peptides Observed during Liquid Chromatography-Mass Spectrometry and Their Effect on Cross-Link Analyses (2019) (16)
Analysis of the topology of protein complexes using cross-linking and mass spectrometry. (2007) (16)
Supraspliceosomes at Defined Functional States Portray the Pre-Assembled Nature of the Pre-mRNA Processing Machine in the Cell Nucleus (2014) (16)
A systematic analysis of Trypanosoma brucei chromatin factors identifies novel protein interaction networks associated with sites of transcription initiation and termination (2021) (16)
Exportin Crm1 is repurposed as a docking protein to generate microtubule organizing centers at the nuclear pore (2017) (15)
Proteome Analysis of Human Neutrophil Granulocytes From Patients With Monogenic Disease Using Data-independent Acquisition. (2019) (15)
An open invitation to the Understudied Proteins Initiative (2022) (15)
The depolymerase activity of MCAK shows a graded response to Aurora B kinase phosphorylation through allosteric regulation (2019) (15)
The domesticated transposase ALP2 mediates formation of a novel Polycomb protein complex by direct interaction with MSI1, a core subunit of Polycomb Repressive Complex 2 (PRC2) (2020) (15)
Hap2–Ino80-facilitated transcription promotes de novo establishment of CENP-A chromatin (2019) (14)
Multiomics Analysis Provides Insight into the Laboratory Evolution of Escherichia coli toward the Metabolic Usage of Fluorinated Indoles (2020) (14)
Cryo‐EM reveals the complex architecture of dynactin's shoulder region and pointed end (2021) (14)
Quantitative Proteomics of the Mitotic Chromosome Scaffold Reveals the Association of BAZ1B with Chromosomal Axes* (2018) (14)
Is mass spectrometry ready for proteome-wide protein expression analysis? (2002) (13)
Nano Random Forests to mine protein complexes and their relationships in quantitative proteomics data (2016) (13)
Cdc14 phosphatase directs centrosome re-duplication at the meiosis I to meiosis II transition in budding yeast (2017) (13)
Multiclassifier combinatorial proteomics of organelle shadows at the example of mitochondria in chromatin data (2016) (13)
Isolation of acetylated and unmodified protein N-terminal peptides by strong cation exchange chromatographic separation of TrypN-digested peptides. (2020) (12)
Data-independent Acquisition Improves Quantitative Cross-linking Mass Spectrometry* (2019) (12)
Retention time prediction using neural networks increases identifications in crosslinking mass spectrometry (2021) (12)
Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests (2016) (12)
Trim 25 Is an RNA-Specific Activator of Lin 28 a / TuT 4-Mediated Uridylation (2014) (12)
False discovery rate estimation and heterobifunctional cross-linkers (2017) (12)
A Primer on Data Analytics in Functional Genomics: How to Move from Data to Insight? (2019) (12)
The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment (2020) (11)
Blind testing cross-linking/mass spectrometry under the auspices of the 11 th critical assessment of methods of protein structure prediction (CASP11) (2016) (11)
STING nuclear partners contribute to innate immune signaling responses (2021) (11)
The Proteomic Landscape of Centromeric Chromatin Reveals an Essential Role for the Ctf19CCAN Complex in Meiotic Kinetochore Assembly (2020) (10)
Complex Portal 2022: new curation frontiers (2021) (10)
Peptide Retention in Hydrophilic Strong Anion Exchange Chromatography Is Driven by Charged and Aromatic Residues (2018) (10)
A protocol for studying structural dynamics of proteins by quantitative crosslinking mass spectrometry and data-independent acquisition. (2020) (9)
Data-independent Acquisition Improves Quantitative Cross-linking Mass Spectrometry. (2019) (9)
The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment (2020) (9)
Chemische Evolution eines bakteriellen Proteoms (2015) (9)
ComplexViewer: visualization of curated macromolecular complexes (2017) (9)
Sequence tag scanning: A new explorative strategy for recognition of unexpected protein alterations by nanoelectrospray ionization‐tandem mass spectrometry (2005) (9)
Explorer Pom 1 regulates the assembly of Cdr 2-Mid 1 cortical nodes for robust spatial control of cytokinesis (2014) (8)
Cross-linking/mass spectrometry as a new field and the proteomics information mountain of tomorrow (2012) (8)
Engineering Pyrrolysyl-tRNA Synthetase for the Incorporation of Non-Canonical Amino Acids with Smaller Side Chains (2021) (8)
Epigenetic Variability Confounds Transcriptome but Not Proteome Profiling for Coexpression-based Gene Function Prediction* (2018) (7)
NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells (2021) (7)
Structural insights into Cullin4-RING ubiquitin ligase remodelling by Vpr from simian immunodeficiency viruses (2021) (7)
Structure of the Fanconi anaemia monoubiquitin ligase complex (2019) (6)
Structure of complement C 3 ( H 2 O ) revealed by quantitative cross-linking / mass spectrometry and modelling (2016) (6)
JAMI: a Java library for molecular interactions and data interoperability (2018) (6)
Protein complexes in cells by AI‐assisted structural proteomics (2023) (6)
A generic solution for quantifying cross-linked peptides using software Skyline (2018) (6)
Deletion of Genes Encoding Arginase Improves Use of “Heavy” Isotope-Labeled Arginine for Mass Spectrometry in Fission Yeast (2015) (6)
Correction to Optimized Fragmentation Regime for Diazirine Photo-Cross-Linked Peptides (2017) (5)
Mpe1 senses the polyadenylation signal in pre-mRNA to control cleavage and polyadenylation (2021) (5)
Improved Peptide Backbone Fragmentation Is the Primary Advantage of MS-Cleavable Crosslinkers (2021) (5)
Specific recognition and ubiquitination of slow-moving ribosomes by human CCR4-NOT (2022) (5)
15:30 STRUCTURAL ELUCIDATION OF DISC1 PATHWAY PROTEINS USING ELECTRON MICROSCOPY, CHEMICAL CROSS-LINKING AND MASS SPECTROSCOPY (2012) (5)
Mapping the invisible chromatin transactions of prophase chromosome remodeling (2021) (5)
Mpe1 senses the binding of pre-mRNA and controls 3′ end processing by CPF (2022) (5)
Identification of RNA-associated peptides, iRAP, defines precise sites of protein-RNA interaction (2018) (5)
Megadalton-sized Dityrosine Aggregates of α-Synuclein Retain High Degrees of Structural Disorder and Internal Dynamics (2020) (5)
RNA pull-down confocal nanoscanning (RP-CONA) detects quercetin as pri-miR-7/HuR interaction inhibitor that decreases α-synuclein levels (2021) (4)
The DNA-damage kinase ATR activates the FANCD2-FANCI clamp by priming it for ubiquitination (2022) (4)
Generation of glycan-specific nanobodies. (2022) (4)
Compositional Dynamics: Defining the Fuzzy Cell (2016) (4)
SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase (2021) (4)
Peptide identification using vectors of small fragment ions. (2005) (3)
Quantitative Proteomics of the Mitotic Chromosome Scaffold Reveals the Association of BAZ1B with Chromosomal Axes. (2019) (3)
Leveraging Parameter Dependencies in High-Field Asymmetric Waveform Ion-Mobility Spectrometry and Size Exclusion Chromatography for Proteome-wide Cross-Linking Mass Spectrometry (2022) (3)
Ultraviolet Photodissociation of Tryptic Peptide Backbones at 213 nm (2020) (3)
Isolation of Acetylated and Unmodified Protein N-Terminal Peptides by Strong Cation Exchange Chromatographic Separation of TrypN-Digested Peptides (2020) (3)
Non-redundant functions of H2A.Z.1 and H2A.Z.2 in chromosome segregation and cell cycle progression (2020) (3)
Towards Increased Reliability, Transparency and Accessibility in Crosslinking Mass Spectrometry (2020) (3)
Cross-linking/Mass Spectrometry: A Community-Wide, Comparative Study Towards Establishing Best Practice Guidelines (2018) (3)
Purification of native SMN complexes and identification of Gemin 6 as a novel component (2001) (2)
Epigenetic Variability Confounds Transcriptome but Not Proteome Profiling for Coexpression-based Gene Function Prediction. (2018) (2)
The human proteome co-regulation map reveals functional relationships between proteins (2019) (2)
Molecular Basis for CPC-Sgo1 Interaction: Implications for Centromere Localisation and Function of the CPC (2021) (2)
Architecture of TAF11/TAF13/TBP complex suggests novel regulatory state in General Transcription Factor TFIID function (2017) (2)
Proteasome-dependent truncation of the negative heterochromatin regulator Epe1 mediates antifungal resistance (2021) (2)
Human genetic defects in SRP19 and SRPRA cause severe congenital neutropenia with distinctive proteome changes. (2022) (2)
Kicking against the PRCs (2015) (2)
SARS-CoV-2 Nsp1 N-terminal and linker regions as a platform for host translational shutoff (2022) (2)
Protein structure prediction with in-cell photo-crosslinking mass spectrometry and deep learning. (2023) (2)
Cryo-EM reveals the complex architecture of dynactin’s shoulder and pointed end (2020) (2)
DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network (2022) (2)
The phospho-docking protein 14-3-3 regulates microtubule-associated proteins in oocytes including the chromosomal passenger Borealin (2021) (1)
Mechanistic basis for Sgo1-mediated centromere localization and function of the CPC (2022) (1)
Erratum: A model for transmission of the H3K27me3 epigenetic mark (Nature Cell Biology (2008) vol. 10 (1291-1300)) (2008) (1)
STING Nuclear Partners Contribute to Innate Immune Signalling Responses (2020) (1)
Author response: Shugoshin biases chromosomes for biorientation through condensin recruitment to the pericentromere (2013) (1)
Dual-Bioorthogonal Catalysis by a Palladium Peptide Complex (2023) (1)
Multi-Protein Complexes Studied by Mass Spectrometry (2002) (1)
treeClust improves protein co-regulation analysis due to robust selectivity for close linear relationships (2019) (1)
Explorer A Functional Link between the Histone Demethylase PHF 8 and the Transcription Factor ZNF 711 in X-Linked Mental Retardation (2017) (1)
JAMI: a Java library for molecular interactions and data interoperability (2018) (1)
A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast (2014) (1)
Fission yeast NDR/LATS kinase Orb6 regulates exocytosis via phosphorylation of exocyst complex (2018) (1)
by Mass Spectrometry and Computational Biology (2015) (1)
Resource Proteomics of a fuzzy organelle : interphase chromatin (2014) (1)
Isolation of protein N-terminal peptides by charge-mediated position-selective enrichment using strong cation exchange chromatography (2020) (1)
Direct Nucleosome Binding of Borealin Secures Chromosome Association and Function of the Chromosomal Passenger complex (2019) (1)
Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions (2018) (1)
Structural mechanism of CRL4‐instructed STAT2 degradation via a novel cytomegaloviral DCAF receptor (2023) (1)
A Focus on Chromatin Proteomics (2016) (1)
Molecular architectures of the 24meric eye lens chaperone alphaB- crystallin elucidated by a triple hybrid approach (2011) (1)
Erratum to: Assessment of chemical-crosslink-assisted protein structure modeling in CASP13 (Proteins: Structure, Function, and Bioinformatics, (2019), 87, 12, (1283-1297), 10.1002/prot.25816) (2020) (1)
Integrative structural analysis of the type III secretion system needle complex from Shigella flexneri (2023) (1)
Erratum to: Assessment of chemical-crosslink-assisted protein structure modeling in CASP13 (Proteins: Structure, Function, and Bioinformatics, (2019), 87, 12, (1283-1297), 10.1002/prot.25816) (2020) (1)
An energy charge sensor for balancing RNA polymerase recycling and hibernation (2020) (1)
Explorer Fission yeast NDR / LATS kinase Orb 6 regulates exocytosis via phosphorylation of exocyst complex (2019) (0)
Edinburgh Research Explorer The histone lysine demethylase JMJD3/KDM6B Is recruited to p53 bound promoters and enhancer elements in a p53 dependent manner (2017) (0)
Edinburgh Research Explorer Structure of complement C3(H2O) revealed by quantitative cross-linking/mass spectrometry and modelling (2018) (0)
Repo-Man / PP 1 regulates heterochromatin formation 1 in interphase (2017) (0)
Comprehensive proteomic profiling of chromatin environment surrounding stressed replication fork (2015) (0)
A folded conformation of MukBEF and cohesin (2019) (0)
DomainRank: Improving Biological Data Sets With Domain Knowledge and Google’s PageRank (2022) (0)
Edinburgh Research Explorer The depolymerase activity of MCAK shows graded response to Aurora B kinase phosphorylation through allosteric regulation (2019) (0)
A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis (2019) (0)
Quantitative cross-linking/mass spectrometry to elucidate structural changes in proteins and their complexes (2018) (0)
Microtubule Nucleation Properties of Single Human γTurcs Investigated by TIRF Microscopy and Cryo-Electron Microscopy (2021) (0)
Defects in Signal Recognition Particle (SRP) Components Reveal an Essential and Non-Redundant Role for Granule Biogenesis and Differentiation of Neutrophil Granulocytes (2019) (0)
Nucleosomal Asymmetry Shapes Histone Mark Binding and Promotes Poising at Bivalent Domains (2021) (0)
Crystal structure of a bonsai version of the human Ndc80 complex (2008) (0)
The SPARC complex defines RNAPII promoters in Trypanosoma brucei (2022) (0)
The role of PrP and other proteins in prion diseases (2009) (0)
Repo-Man / PP 1 regulates heterochromatin formation in interphase 1 2 (2016) (0)
Monitor complement activation in serum by quantitative cross-linking/mass spectrometry (2018) (0)
The structure of human thyroglobulin- 2019-07-11446A (2020) (0)
A novel combination of chemical cross-linking, mass spectrometry and NMR reveals the architecture of complement component C7 (2008) (0)
Swr1 mediated H2A.ZPht1 incorporation designates centromere DNA for de novo CENP-ACnp1 assembly (2017) (0)
Supporting Advances in Proteome Informatics*□S (2020) (0)
Cleavable crosslinkers redefined by novel MS3-trigger algorithm (2023) (0)
Movie S2. GFP:Repo-Man1–397 Localizes to the Chromosomes Periphery in Telophase (2011) (0)
Inside Cover: Chemical Evolution of a Bacterial Proteome (Angew. Chem. Int. Ed. 34/2015) (2015) (0)
Edinburgh Research Explorer Structure of hibernating ribosomes studied by cryoelectron tomography in vitro and in situ (2018) (0)
Edinburgh Research Explorer Multiomics analysis provides insight into the laboratory evolution of Escherichia coli towards the metabolic usage of fluorinated indoles (2020) (0)
Loss of 5-methylcytosine alters the biogenesis of vault-derived small RNAs to coordinate epidermal differentiation (2019) (0)
Deposited in DRO : 25 January 2017 Version of attached le : Published Version Peer-review status of attached (2018) (0)
Movie S1. GFP:Repo-Man 403–1023 Localizes to Bulk Chromatin after Anaphase Onset (2011) (0)
Assessment of chemical‐crosslink‐assisted protein structure modeling in CASP13 (2020) (0)
Outer Dynein Arm-Shulin complex - Dyh3 motor region (Tetrahymena thermophila) (2021) (0)
Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes (2021) (0)
Crystal Structure of Drosophila CAL1 1-160 bound to CENP-A/H4 (2020) (0)
Automated peptide sequence tag determination in stable isotope pairs of tandem mass spectra in quantitative proteomics (2002) (0)
1 Swr 1 mediated H 2 A . ZPht 1 incorporation designates centromere DNA for de novo CENP-ACnp 1 assembly (2017) (0)
Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity (2019) (0)
Lamin A conformation modelling (2019) (0)
The molecular basis of monopolin recruitment to the kinetochore (2019) (0)
Defining gene function via the mass spectrometric analysis of multiprotein complexes (2000) (0)
Higher-order modular regulation of the human proteome. (2023) (0)
Structural Basis for CAL1-Mediated Centromere Maintenance (2019) (0)
Using multi-dimensional proteomics to define the complete protein composition of mitotic chromosomes (2009) (0)
The phospho-docking protein 14-3-3 regulates microtubule-associated proteins in oocytes including the chromosomal passenger Borealin (2022) (0)
Indirect Bacterial Transcription-Translation Coupling Mechanism Revealed by In Situ Integrative Structural Biology (2020) (0)
Correction: Kicking against the PRCs - A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2 (2016) (0)
Non-covalently-associated peptides are observed during liquid chromatography-mass spectrometry and affect crosslink analyses (2018) (0)
Naturstoffanalytik unter der Lupe (2003) (0)
Biochemie und Molekulargenetik 2001 (2002) (0)
The structure of human thyroglobulin (2020) (0)
mRNA recognition and packaging by the human transcription–export complex (2023) (0)
Molecular interactions between Hel2 and RNA supporting ribosome-associated quality control (2019) (0)
Structure and mechanism of a novel cytomegaloviral DCAF mediating interferon antagonism (2022) (0)
Cryo-EM structure of the fully assembled Elongator complex (2023) (0)
Explorer Protein Tertiary Structure by Crosslinking / Mass Spectrometry (2018) (0)
Edinburgh Research Explorer Complementary Benzophenone Cross-Linking/Mass Spectrometry Photochemistry (2017) (0)
Faculty Opinions recommendation of Photo-Cross-Linking Mass Spectrometry and Integrative Modeling Enables Rapid Screening of Antigen Interactions Involving Bacterial Transferrin Receptors. (2019) (0)
Publisher Correction: Visualizing translation dynamics at atomic detail inside a bacterial cell (2022) (0)
Direct Evidence for Sister Kinetochore Fusion in Meiosis I (2014) (0)
Supramolecular complexes involved in the coordination of transcription and translation. (2023) (0)
Innentitelbild: Chemische Evolution eines bakteriellen Proteoms (Angew. Chem. 34/2015) (2015) (0)
FANCD2–FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair (2020) (0)
Symposia (2016) (0)
Explorer Noncovalently associated peptides are observed during liquid chromatography-mass spectrometry and effect cross-link analyses (2019) (0)
Crystal structure of drosophila melanogaster CENP-C bound to CAL1 (2020) (0)
The structure and oxidation of the eye lens chaperone αA-crystallin (2019) (0)
Molecular architecture of the Dam 1 complex-microtubule 1 interaction (2016) (0)
Evolving a mitigation of the stress response pathway to change the basic chemistry of life (2021) (0)
Cross-linking mass spectrometry: methods and applications in structural, molecular and systems biology (2018) (0)
Quantitative Crosslinking Mass Spectrometry: Development and Application to Protein Conformation Changes (2020) (0)
Key mechanism in the loading and activation of the replicative helicase MCM2-7 (2016) (0)
Explorer Kinase Activity of Fission Yeast Mph 1 Is Required for Mad 2 and Mad 3 to Stably Bind the Anaphase Promoting Complex (2012) (0)
Edinburgh Research Explorer Compositional dynamics (2016) (0)
Architecture of TAF 11 / TAF 13 / TBP complex suggests novel 1 regulatory state in General Transcription Factor TFIID function 2 3 (2017) (0)
Architecture of the Mto1/2 microtubule nucleation complex (2019) (0)
Substrate specificity of the TRAMP nuclear surveillance complexes (2020) (0)
Structural Basis for the microtubule binding of the human kinetochore Ska complex (2014) (0)
drosophila melanogaster CENP-A/H4 bound to N-terminal CAL1 fragment (2020) (0)
The Peptide MS/MS-Fragmentome: A Set of Predictable Fragment Ions with Highly Redundant Sequence Information (2005) (0)
Structural Basis for Mis18 Complex Assembly: Implications for Centromere Maintenance (2021) (0)
Biophysical Measurements Reveal Fusion of Sister Kinetochores during Meiosis I (2014) (0)
Human mitochondrial genome can replicate in the Yarrowia lipolytica yeast (2016) (0)
The active conformation of complement factor H is revealed upon its irreversible capture by a bacterial protein (2014) (0)
Crystal structure of drosophila melanogaster CENP-C cumin domain (2020) (0)
RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination (2017) (0)
Addition of Hop (Humulus Lupulus L.) Bitter Acids Yields Modification of Malt Protein Aggregate Profiles during Wort Boiling. (2023) (0)
Ki-67 is necessary during DNA replication for forks protection and genome stability (2023) (0)
Protein structure dynamics by crosslinking mass spectrometry. (2023) (0)
AI-guided cryo-EM probes a thermophilic cell-free system with succinyl-coA manufacturing capability (2022) (0)
Correction: Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests (2016) (0)
Correction (2013) (0)
Edinburgh Explorer Posttranscriptional Regulation of 14q32 microRNAs by RNA Binding Proteins CIRBP and HADHB during Vascular Regeneration after Ischemia (2018) (0)
Mps1 Kinase Phosphorylates Mad3 to Inhibit Cdc20-APC/C and Maintain Spindle Checkpoint Arrests (2016) (0)
Laboratory evolution of Escherichia coli enables life based on fluorinated amino acids (2019) (0)

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