Karen A. Holbrook
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Why Is Karen A. Holbrook Influential?
(Suggest an Edit or Addition)Karen A. Holbrook's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Revised clinical and laboratory criteria for subtypes of inherited epidermolysis bullosa. A consensus report by the Subcommittee on Diagnosis and Classification of the National Epidermolysis Bullosa Registry. (1991) (488)
- Calcium regulation of cell-cell contact and differentiation of epidermal cells in culture. An ultrastructural study. (1983) (374)
- Regional differences in the thickness (cell layers) of the human stratum corneum: an ultrastructural analysis. (1974) (333)
- Expression of epidermal keratins and filaggrin during human fetal skin development (1985) (277)
- Ichthyosis vulgaris: identification of a defect in synthesis of filaggrin correlated with an absence of keratohyaline granules. (1985) (276)
- Assembly of stratum corneum basic protein and keratin filaments in macrofibrils (1978) (261)
- Immunolocalization of epidermal growth factor receptors in normal developing human skin. (1990) (196)
- X-linked cutis laxa: defective cross-link formation in collagen due to decreased lysyl oxidase activity. (1980) (191)
- The fine structure of developing human epidermis: light, scanning, and transmission electron microscopy of the periderm. (1975) (179)
- Structural abnormalities in the dermal collagen and elastic matrix from the skin of patients with inherited connective tissue disorders. (1982) (178)
- Collagen types I, III, and V in human embryonic and fetal skin. (1986) (172)
- Altered triple helical structure of type I procollagen in lethal perinatal osteogenesis imperfecta. (1985) (172)
- Abnormal collagen fibril structure in the gravis form (type I) of Ehlers-Danlos syndrome. (1979) (155)
- Phenotypic expression of epidermal cells in vitro: a review. (1983) (145)
- PREGNANCY COMPLICATIONS IN TYPE IV EHLERS-DANLOS SYNDROME (1983) (136)
- Profilaggrin, a high-molecular-weight precursor of filaggrin in human epidermis and cultured keratinocytes. (1985) (132)
- Heterogeneity in harlequin ichthyosis, an inborn error of epidermal keratinization: variable morphology and structural protein expression and a defect in lamellar granules. (1990) (130)
- Structure of the dermal matrix during development and in the adult. (1982) (128)
- Properties of carcinogen altered mouse epidermal cells resistant to calcium-induced terminal differentiation. (1983) (107)
- Factors influencing calcium‐induced terminal differentiation in cultured mouse epidermal cells (1983) (98)
- Abnormal lamellar granules in harlequin ichthyosis. (1992) (96)
- The appearance, density, and distribution of Merkel cells in human embryonic and fetal skin: their relation to sweat gland and hair follicle development. (1995) (94)
- Human Epidermal Embryogenesis (1979) (92)
- Characterization of hair follicle bulge in human fetal skin: the human fetal bulge is a pool of undifferentiated keratinocytes. (1995) (92)
- Altered secretion of type III procollagen in a form of type IV Ehlers-Danlos syndrome. Biochemical studies in cultured fibroblasts. (1981) (92)
- Restrictive dermopathy: a newly recognized autosomal recessive skin dysplasia. (1986) (90)
- Growth factor and growth factor receptor localization in the hair follicle bulge and associated tissue in human fetus. (1996) (89)
- Skin is a window on heritable disorders of connective tissue. (1989) (89)
- Fatal cardiovascular disease and cutis laxa following acute febrile neutrophilic dermatosis. (1983) (84)
- Marfan syndrome: abnormal alpha 2 chain in type I collagen. (1981) (79)
- Rates of and Risk Factors for Trichomoniasis Among Pregnant Inmates in New York City (1998) (77)
- Logistics of community smallpox control through contact tracing and ring vaccination: a stochastic network model (2004) (74)
- Abnormal alpha 2-chain in type I collagen from a patient with a form of osteogenesis imperfecta. (1983) (74)
- The lamellar granules of epidermis. (1981) (72)
- Dynamic expression patterns of tenascin, proteoglycans, and cell adhesion molecules during human hair follicle morphogenesis (1994) (72)
- Topical ocular antibiotics induce bacterial resistance at extraocular sites (2005) (72)
- Dermatosparaxis in a Himalayan cat: II. Ultrastructural studies of dermal collagen. (1980) (70)
- Regional development of the human epidermis in the first trimester embryo and the second trimester fetus (ages related to the timing of amniocentesis and fetal biopsy). (1980) (70)
- Periderm cells form cornified cell envelope in their regression process during human epidermal development. (1999) (68)
- Growth and differentiation of mouse epidermal cells in culture: effects of extracellular calcium. (1981) (68)
- Disappearance of trachoma from Western Nepal. (2002) (67)
- The appearance, density and distribution of melanocytes in human embryonic and fetal skin revealed by the anti-melanoma monoclonal antibody, HMB-45 (2004) (66)
- Familial pityriasis rubra pilaris. (1995) (64)
- Hair Follicle Embryogenesis in the Human (1991) (64)
- Heterozygosity for a large deletion in the alpha 2(I) collagen gene has a dramatic effect on type I collagen secretion and produces perinatal lethal osteogenesis imperfecta. (1988) (63)
- Epidermolytic hyperkeratosis: ultrastructure and biochemistry of skin and amniotic fluid cells from two affected fetuses and a newborn infant. (1983) (63)
- The appearance of four basement membrane zone antigens in developing human fetal skin. (1984) (60)
- Expression of morphogens during human follicle development in vivo and a model for studying follicle morphogenesis in vitro. (1993) (59)
- Dermatosparaxis in a Himalayan cat: I. Biochemical studies of dermal collagen. (1980) (59)
- Ontogeny of structural components at the dermal-epidermal junction in human embryonic and fetal skin: the appearance of anchoring fibrils and type VII collagen. (1988) (58)
- Prenatal diagnosis of lethal perinatal osteogenesis imperfecta (OI type II). (1982) (58)
- Ultrastructural characteristics of the skin in a form of the Ehlers-Danlos syndrome type IV. Storage in the rough endoplasmic reticulum. (1981) (56)
- Heterogeneity of elastin expression in cutis laxa fibroblast strains. (1989) (56)
- Genetic disorders of collagen metabolism. (1982) (55)
- Prenatal diagnosis of genetic skin disease using fetal skin biopsy samples. (1993) (54)
- Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network (1993) (54)
- Characteristic morphologic abnormality of harlequin ichthyosis detected in amniotic fluid cells. (1994) (52)
- Potassium mediation of calcium-induced terminal differentiation of epidermal cells in culture. (1983) (52)
- Arrested epidermal morphogenesis in three newborn infants with a fatal genetic disorder (restrictive dermopathy). (1987) (50)
- The CHILD syndrome. Histologic and ultrastructural studies. (1987) (50)
- Biologic structure and function: perspectives on morphologic approaches to the study of the granular layer keratinocyte. (1989) (50)
- Structure of the human fetal hair canal and initial hair eruption. (1978) (49)
- Postinflammatory elastolysis and cutis laxa. A case report. (1990) (49)
- Skin lipid content during early fetal development. (1988) (47)
- Extracutaneous epithelial involvement in inherited epidermolysis bullosa. (1988) (47)
- Keratinocytes cultured from subjects with ichthyosis vulgaris are phenotypically abnormal. (1987) (46)
- Palmar-plantar keratoderma. A clinical, ultrastructural, and biochemical study. (1988) (45)
- Regional difference in expression of characteristic abnormality of harlequin ichthyosis in affected fetuses (1998) (43)
- Community treatment with azithromycin for trachoma is not associated with antibiotic resistance in Streptococcus pneumoniae at 1 year (2003) (42)
- A familial cutis laxa syndrome with ultrastructural abnormalities of collagen and elastin. (1980) (39)
- Infantile Systemic Hyalinosis in a Black Infant (1994) (37)
- Comparison of endovascular and conventional vascular prostheses in an experimental infection model. (1996) (37)
- Staphylococcus aureus nasal colonization in HIV-seropositive and HIV-seronegative drug users. (1997) (36)
- Embryogenesis of the Dermis in Human Skin (1986) (35)
- Development of human embryonic and fetal dermal vasculature. (1989) (34)
- Abnormal Epidermal Keratinization in the repeated epilation mutant mouse (1982) (34)
- A collagen and elastic network in the wing of the bat. (1978) (34)
- Differentiation markers in fetal epidermis: transglutaminase and transpeptidase. (1979) (33)
- Clinical and ultrastructural heterogeneity of type IV Ehlers-Danlos syndrome (1979) (33)
- A scanning electron microscope study of the caecal tonsil: the identification of a bacterial attachment to the villi of the caecal tonsil and the possible presence of lymphatics in the caecal tonsil. (1978) (33)
- Melanocytes in Human Embryonic and Fetal Skin: A Review and New Findings (1988) (33)
- Stratum corneum basic protein: an interfilamentous matrix protein of epidermal keratin. (1980) (32)
- National Institutes of Health summary of the Consensus Development Conference on sunlight, ultraviolet radiation, and the skin, Bethesda, Maryland, May 8-10, 1989 (1991) (32)
- Restrictive dermopathy. Report of two affected siblings and a review of the literature. (1992) (32)
- Applicability of 19–DEJ‐l monoclonal antibody for the prenatal diagnosis or exclusion of junctional epidermolysis bullosa (1990) (30)
- Molecular mechanisms of connective tissue abnormalities in the Ehlers-Danlos syndrome. (1981) (30)
- Filaggrin expression in epidermolytic ichthyosis (epidermolytic hyperkeratosis) (1994) (29)
- Hair follicle embryogenesis in the human. Characterization of events in vivo and in vitro. (1991) (29)
- Molecular Basis of Clinical Heterogeneity in the Ehlers‐Danlos Syndrome a (1985) (26)
- The fine structure of the bursa of Fabricius: "B" cell surface configuration and lymphoepithelial organization as revealed by scanning and transmission electron microscopy. (1974) (26)
- Antisense profilaggrin RNA delays and decreases profilaggrin expression and alters in vitro differentiation of rat epidermal keratinocytes. (1993) (25)
- Prenatal diagnosis of congenital non‐bullous ichthyosiform erythroderma (lamellar ichthyosis) (1987) (24)
- Immunolocalization of FXIIIa+ dendritic cells in human burn wounds. (1995) (24)
- Werner's syndrome. Evidence for preferential regional expression of a generalized mesenchymal cell defect. (1988) (23)
- CHILD syndrome: lack of expression of epidermal differentiation markers in lesional ichthyotic skin. (1992) (23)
- The structure and function of dermal connective tissue in normal individuals and patients with inherited connective tissue disorders. (1982) (21)
- Congenital migratory ichthyosiform dermatosis with neurologic and ophthalmologic abnormalities. (1985) (21)
- A model system for long-term serum-free suspension organ culture of human fetal tissues: experiments on digits and skin from multiple body regions (1997) (20)
- Analysis of skin-derived amniotic fluid cells in the second trimester; detection of severe genodermatoses expressed in the fetal period. (1994) (19)
- Morphogenesis of the Hair Follicle during the Ontogeny of Human Skin (1988) (19)
- Cell surface carbohydrate changes during embryonic and fetal skin development. (1986) (18)
- Age-related changes in collagenase expression in cultured embryonic and fetal human skin fibroblasts. (1985) (18)
- EXTRACELLULAR CALCIUM REGULATES GROWTH AND TERMINAL DIFFERENTIATION OF CULTURED MOUSE EPIDERMAL CELLS (1982) (18)
- Antenatal diagnosis of recessive dystrophic epidermolysis bullosa: collagenase expression in cultured fibroblasts as a biochemical marker. (1986) (18)
- Prenatal diagnosis of dominant and recessive dystrophic epidermolysis bullosa: application and limitations in the use of KF-1 and LH 7:2 monoclonal antibodies and immunofluorescence mapping technique. (1988) (17)
- Developmental expression of human epidermal keratins and filaggrin. (1987) (17)
- The expression of congenital ichthyosiform erythroderma in second trimester fetuses of the same family: morphologic and biochemical studies. (1988) (17)
- Structural abnormalities of the epidermally derived appendages in skin from patients with ectodermal dysplasia: insight into developmental errors. (1988) (17)
- An electron and light microscope study on the caecal tonsil: the basic unit of the caecal tonsil. (1981) (16)
- Development of dermal connective tissue in human embryonic and fetal skin. (1982) (16)
- Intermediate Filament Associated Protein of Epidermis (1988) (16)
- Prenatal diagnosis of severe dermatologic diseases. (1992) (16)
- The Biology of Human Fetal Skin at Ages Related to Prenatal Diagnosis (1983) (15)
- Platelet adherence in endothelial cell cultures. (1979) (15)
- Scanning electron microscopy of the bursa of Fabricius from normal and testosterone-treated embryos. (1977) (15)
- Molecular pathology in inherited disorders of collagen metabolism. (1982) (14)
- Contact sites between lymphoid cells of the bursa of fabricius, in vivo and in vitro (1977) (14)
- Growth factor receptors and hair loss. (1991) (13)
- Ultrasound-Guided Fetal Skin Sampling for Prenatal Diagnosis of Genodermatoses (1994) (13)
- Separation of Noncutaneous Epithelia in a Fetus Diagnosed In Utero with Junctional Epidermolysis Bullosa (1992) (12)
- Diagnosis and prenatal diagnosis of epidermolysis bullosa herpetiformis (Dowling‐Meara) in a mother, two affected children, and an affected fetus (1992) (12)
- Embedding prolene for the development of fiducial markers (1989) (12)
- Morphometric and statistical analyses describing the In utero growth of human epidermis (1988) (11)
- Ontogeny and characterization of Factor XIIIa+ cells in developing human skin (2004) (11)
- Prenatal diagnosis of herlitz junctional epidermolysis bullosa by amniocentesis (1995) (11)
- Markers of adult skin expressed in the skin of the first trimester fetus. (1987) (10)
- Transglutaminase and major cornified cell envelope precursor proteins, loricrin, small proline-rich proteins 1 and 2, and involucrin are coordinately expressed in the sites defined to form hair canal in developing human hair follicle. (1999) (9)
- Ultrastructural aspects of human skin during the embryonic, fetal, premature, neonatal, and adult periods of life. (1981) (9)
- Prenatal diagnosis and screening. (1987) (8)
- Morphology and Chemical Composition of Connective Tissue: Structure of the Skin and Tendon (2003) (8)
- Abnormal keratinization in restrictive dermopathy. (1987) (7)
- Electron microscopy as an aid to diagnosis of disorders of the extracellular matrix: a new type of spondyloepiphyseal dysplasia. (1978) (7)
- Alpha‐fetoprotein and acetylcholinesterase are not predictive of fetal junctional epidermolysis bullosa, Herlitz variant (1991) (7)
- Biochemical examination of fetal skin biopsy specimens obtained by fetoscopy: Use of the method for analysis of keratins and filaggrin (1986) (7)
- Inhibition of calcium-induced terminal differentiation of epidermal cells by ouabain and A23187. (1983) (6)
- Prenatal Diagnosis and Genetic Screening for Epidermolysis Bullosa (1992) (6)
- The nerve-dependency of Merkel cell proliferation in cultured human fetal glabrous skin. (2001) (6)
- Proceedings of 31st Annual Symposium on the Biology of Skin Structural Elements of the Dermis (1982) (5)
- Role of differentiation in determining responses of epidermal cells to phorbol esters. (1982) (5)
- A new variety of spondyloepiphyseal dysplasia characterized by punctate corneal dystrophy and abnormal dermal collagen fibrils (1978) (5)
- Proceedings of 32nd Annual Symposium on the Biology of Skin Biology of the Keratinocyte in Vitro (1983) (4)
- Ichthyosis, Inherited, Skin, Mouse (ic/ic) (1989) (4)
- Morphogenesis and malformations of the skin NICHD/NIADDK research workshop. (1987) (4)
- Embryogenesis of the Skin (2019) (3)
- A late defect in wound healing associated with recurrent spontaneous pneumothoraces: a presumptive role for abnormal collagenase activity (1995) (2)
- Prenatal Diagnosis of Genodermatoses (1988) (2)
- 174 Cornified cell envelope (CCE) precursor proteins and transglutaminase (TGase) 1 are coordinately expressed in the sites of hair canal morphogenesis during human hair follicle development (1997) (1)
- Response of Karen Holbrook (1993) (1)
- Melanocytic cells in human embryonic and fetal epidermis as identified by the anti melanoma monoclonal antibody hmb 45 (1987) (1)
- 705 BIOCHEMICAL CHARACTERIZATION OF PERINATAL LETHAL OSTEOGENESIS IMPERFECTA (01) AND ITS PRENATAL DETECTION (1981) (1)
- Repeated epilation (ER): a semidominant autosomal gene reducing synthesis of skin filaggrin in mice. (1982) (1)
- Hetero Fibrob Ig eneity of Elastin Expression in Cutis Laxa ast Strains (1989) (1)
- P-Lactam Antibiotics (1998) (1)
- The management of HIV disease in pregnancy. (1992) (1)
- Age-related changes in the cutaneous basal lamina. (1984) (1)
- Disorders of connective tissue metabolism as related to the skin. (1981) (1)
- Viral hemorrhagic fever. (2008) (1)
- ABNORMALITIES IN THE PRODUCTION OF EXTRACELLULAR MATRIX BY CELLS FROM INDIVIDUALS WITH INHERITED DISORDERS OF COLLAGEN BIOSYNTHESIS (1982) (1)
- Emergency Management of Infectious Diseases: Smallpox (2008) (0)
- Alpha‐fetoprotein and acetylcholinesterase are not predictors of fetal junctional epidermolysis bullosa, Herlitz variant (1993) (0)
- Emergency Management of Infectious Diseases: Plague (2008) (0)
- Beta-lactam antibiotics. (1998) (0)
- Emergency Management of Infectious Diseases: Tularemia (2008) (0)
- 7 The management of HIV disease in pregnancy (1992) (0)
- Emergency Management of Infectious Diseases: Botulism (2008) (0)
- Mechanisms of accelerated atherogenesis in 'the pill'-related athero-sclerosis (1978) (0)
- The Expression of Congenital Ichthyosifortn Erythrodertna in Second Tritnester Fetuses of the Satne Fatnily : Morphologic and Biochemical Studies (2010) (0)
- Molecular mechanisms of disease in inherited disorders of collagen metabolism. (1982) (0)
- SocioDemographic Characteristics of Sonoma County (2017) (0)
- Localization of growth factors in human fetal hair follicles in the second trimester (1994) (0)
- Cutis laxa. (1982) (0)
- Emergency Management of Infectious Diseases: Anthrax (2008) (0)
- Lessons on the value of long term follow-up from genetic counselling of a family with severe autosomal recessive congenital ichthyosis. (2022) (0)
- Morphological analysis of amniotic fluid cells: Its contribution to prenatal diagnosis of severe genodermatoses (1993) (0)
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