Keith A. Hruska
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(Suggest an Edit or Addition)Keith A. Hruska's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Osteoporosis prevention, diagnosis, and therapy. (2001) (3506)
- K/DOQI clinical practice guidelines for bone metabolism and disease in chronic kidney disease. (2003) (2521)
- Osteoporosis prevention, diagnosis, and therapy. (2000) (1251)
- Protein transduction: unrestricted delivery into all cells? (2000) (569)
- Hyperphosphatemia of chronic kidney disease. (2008) (373)
- Bone Morphogenetic Proteins in Vascular Calcification (2005) (352)
- Vascular calcification in chronic kidney disease. (2004) (323)
- Metabolism in immunoreactive parathyroid hormone in the dog. The role of the kidney and the effects of chronic renal disease. (1975) (276)
- Rho-A Is Critical for Osteoclast Podosome Organization, Motility, and Bone Resorption* (2000) (271)
- Gelsolin Deficiency Blocks Podosome Assembly and Produces Increased Bone Mass and Strength (2000) (262)
- A microRNA expression signature of osteoclastogenesis. (2011) (257)
- Wnt-dependent beta-catenin signaling is activated after unilateral ureteral obstruction, and recombinant secreted frizzled-related protein 4 alters the progression of renal fibrosis. (2005) (253)
- Osteopontin deficiency produces osteoclast dysfunction due to reduced CD44 surface expression. (2003) (249)
- Osteogenic protein-1 prevents renal fibrogenesis associated with ureteral obstruction. (2000) (243)
- Bone morphogenic protein-7 (BMP-7), a novel therapy for diabetic nephropathy. (2003) (241)
- Osteoclast cytosolic calcium, regulated by voltage-gated calcium channels and extracellular calcium, controls podosome assembly and bone resorption (1990) (238)
- Pathophysiological mechanisms of vascular calcification in end-stage renal disease. (2001) (237)
- Vitamin D receptor activators can protect against vascular calcification. (2008) (226)
- The peripheral metabolism of parathyroid hormone. (1979) (223)
- BMP-7 is an efficacious treatment of vascular calcification in a murine model of atherosclerosis and chronic renal failure. (2003) (220)
- Bone morphogenetic protein-7 improves renal fibrosis and accelerates the return of renal function. (2002) (218)
- The mechanism of phosphorus as a cardiovascular risk factor in CKD. (2008) (218)
- Stimulation of inositol trisphosphate and diacylglycerol production in renal tubular cells by parathyroid hormone. (1987) (217)
- Impaired Micro-RNA Pathways Diminish Osteoclast Differentiation and Function* (2009) (205)
- Human osteoblast-like cells respond to mechanical strain with increased bone matrix protein production independent of hormonal regulation. (1995) (204)
- Early chronic kidney disease-mineral bone disorder stimulates vascular calcification (2013) (194)
- Differential growth factor control of bone formation through osteoprogenitor differentiation. (2004) (191)
- MicroRNA‐223 is a key factor in osteoclast differentiation (2007) (186)
- Akt1/Akt2 and Mammalian Target of Rapamycin/Bim Play Critical Roles in Osteoclast Differentiation and Survival, Respectively, Whereas Akt Is Dispensable for Cell Survival in Isolated Osteoclast Precursors* (2005) (185)
- Nongenomic activation of the calcium message system by vitamin D metabolites in osteoblast-like cells. (1990) (179)
- Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome. (2005) (163)
- Impaired parathyroid hormone metabolism in patients with chronic renal failure. (1978) (162)
- Reconstitution of stretch-activated cation channels by expression of the alpha-subunit of the epithelial sodium channel cloned from osteoblasts. (1997) (158)
- The pathogenesis of osteodystrophy after renal transplantation as detected by early alterations in bone remodeling. (2003) (156)
- HLA-DR associates with specific stress proteins and is retained in the endoplasmic reticulum in invariant chain negative cells (1992) (147)
- Extracellular protons acidify osteoclasts, reduce cytosolic calcium, and promote expression of cell-matrix attachment structures. (1989) (144)
- CKD-induced wingless/integration1 inhibitors and phosphorus cause the CKD-mineral and bone disorder. (2014) (142)
- The renal handling of parathyroid hormone. Role of peritubular uptake and glomerular filtration. (1977) (138)
- Parathyroid hormone acutely elevates intracellular calcium in osteoblastlike cells. (1987) (135)
- Rho family GTPases regulate VEGF-stimulated endothelial cell motility. (2001) (134)
- The Integrin {alpha}v{beta}3 and CD44 Regulate the Actions of Osteopontin on Osteoclast Motility (2003) (133)
- Regulation of canine renal vesicle Pi transport by growth hormone and parathyroid hormone. (1980) (130)
- Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity. (1995) (127)
- Increased monocyte interleukin-1 activity and decreased vertebral bone density in patients with fasting idiopathic hypercalciuria. (1990) (126)
- Correlation of plasma concentrations of cystatin C and creatinine to inulin clearance in a pediatric population. (1998) (125)
- The chronic kidney disease - Mineral bone disorder (CKD-MBD): Advances in pathophysiology. (2017) (124)
- Inhibition of cell survival signal protein kinase B/Akt by curcumin in human prostate cancer cells (2003) (121)
- Mechanically Strained Cells of the Osteoblast Lineage Organize Their Extracellular Matrix Through Unique Sites of αVβ3‐Integrin Expression (2000) (120)
- Ma-huang strikes again: ephedrine nephrolithiasis. (1998) (116)
- Selective uptake of intact parathyroid hormone by the liver: differences between hepatic and renal uptake. (1976) (116)
- PTH receptor coupling to phospholipase C is an alternate pathway of signal transduction in bone and kidney. (1990) (114)
- The cell survival signal Akt is differentially activated by PDGF‐BB, EGF, and FGF‐2 in osteoblastic cells (2001) (114)
- The connections between vascular calcification and bone health. (2011) (112)
- Reversal of the adynamic bone disorder and decreased vascular calcification in chronic kidney disease by sevelamer carbonate therapy. (2007) (110)
- PTH elevates inositol polyphosphates and diacylglycerol in a rat osteoblast-like cell line. (1988) (109)
- Osteopontin stimulates gelsolin-associated phosphoinositide levels and phosphatidylinositol triphosphate-hydroxyl kinase. (1996) (109)
- CKD accelerates development of neointimal hyperplasia in arteriovenous fistulas. (2009) (108)
- Successful treatment of an adynamic bone disorder with bone morphogenetic protein-7 in a renal ablation model. (2004) (107)
- Parathyroid Hormone-induced Bone Resorption Does Not Occur in the Absence of Osteopontin* (2001) (106)
- In Vitro Generation of Scaffold Independent Neocartilage (2001) (105)
- c-Src Is Required for Stimulation of Gelsolin-associated Phosphatidylinositol 3-Kinase* (1998) (105)
- PTEN Regulates RANKL- and Osteopontin-stimulated Signal Transduction during Osteoclast Differentiation and Cell Motility* (2003) (102)
- Phosphatidylinositol 3,4,5-Trisphosphate Directs Association of Src Homology 2-containing Signaling Proteins with Gelsolin* (2001) (101)
- Chronic, intermittent loading alters mechanosensitive channel characteristics in osteoblast-like cells. (1994) (100)
- Phosphate control and 25-hydroxycholecalciferol administration in preventing experimental renal osteodystrophy in the dog. (1977) (99)
- Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7. (2002) (99)
- Effects of parathyroid hormone on cytosolic calcium in renal proximal tubular primary cultures. (1986) (98)
- Down‐regulation of miR‐21 biogenesis by estrogen action contributes to osteoclastic apoptosis (2013) (92)
- Cyclic AMP-dependent protein phosphorylation in canine renal brush-border membrane vesicles is associated with decreased phosphate transport. (1982) (91)
- Selective uptake of the synthetic amino terminal fragment of bovine parathyroid hormone by isolated perfused bone. (1978) (89)
- PHOSPHORUS METABOLISM AND MANAGEMENT IN CHRONIC KIDNEY DISEASE: Renal Osteodystrophy, Phosphate Homeostasis, and Vascular Calcification (2007) (87)
- Degradation of parathyroid hormone and fragment production by the isolated perfused dog kidney. The effect of glomerular filtration rate and perfusate CA++ concentrations. (1977) (86)
- Peripheral metabolism of intact parathyroid hormone. Role of liver and kidney and the effect of chronic renal failure. (1981) (86)
- Renal osteodystrophy. (1995) (85)
- Activin A stimulates IκB‐α/NFκB and rank expression for osteoclast differentiation, but not AKT survival pathway in osteoclast precursors (2003) (84)
- Decreased phosphate reabsorption after renal transplantation: Evidence for a mechanism independent of calcium and parathyroid hormone. (1981) (81)
- Rho-dependent Rho Kinase Activation Increases CD44 Surface Expression and Bone Resorption in Osteoclasts* (2003) (81)
- Adenovirus Mediated BMP‐13 Gene Transfer Induces Chondrogenic Differentiation of Murine Mesenchymal Progenitor Cells (2004) (79)
- Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET-signaling complex in a cohort of living US patients with urinary tract malformations (2012) (79)
- Parathyroid hormone-related peptide transiently increases cytosolic calcium in osteoblast-like cells: comparison with parathyroid hormone. (1989) (78)
- 1 alpha,25-dihydroxyvitamin D3 up-regulates expression of the osteoclast integrin alpha v beta 3. (1993) (78)
- Stretch-induced atriopeptin secretion in the isolated rat myocyte and its negative modulation by calcium. (1989) (76)
- Parathyroid hormone activation of stretch‐activated cation channels in osteosarcoma cells (UMR‐106.01) (1992) (75)
- Parathyroid hormone metabolism and its potential as a uremic toxin. (1980) (74)
- Phosphate homeostasis in CKD: report of a scientific symposium sponsored by the National Kidney Foundation. (2013) (74)
- The predictability of the histological features of uremic bone disease by non-invasive techniques (1978) (74)
- Do parathyroid hormone and 1,25-dithydroxyvitamin D modulate bone formation in uremia? (1980) (73)
- Rac Regulates Vascular Endothelial Growth Factor Stimulated Motility (2001) (72)
- How important is phosphate in the pathogenesis of renal osteodystrophy? (1978) (72)
- Identification of the type II Na(+)-Pi cotransporter (Npt2) in the osteoclast and the skeletal phenotype of Npt2-/- mice. (2001) (71)
- Effects of Phosphate Binder Therapy on Vascular Stiffness in Early-Stage Chronic Kidney Disease (2013) (69)
- Bone morphogenetic protein 7: a novel treatment for chronic renal and bone disease (2004) (69)
- Regulation of αVβ3 and αVβ5 integrins by dexamethasone in normal human osteoblastic cells (2000) (68)
- Expression of p27Kip1 in osteoblast-like cells during differentiation with parathyroid hormone. (1997) (65)
- Parathyroid hormone stimulation of renal phosphoinositide metabolism is a cyclic nucleotide-independent effect. (1982) (65)
- Mechanically strained cells of the osteoblast lineage organize their extracellular matrix through unique sites of alphavbeta3-integrin expression. (2000) (65)
- New insights into mineral and skeletal regulation by active forms of vitamin D. (2006) (65)
- Cellular distribution and regulation of NHE-1 isoform of the NA-H exchanger in the avian osteoclast. (1996) (64)
- Association of 1 alpha,25-dihydroxyvitamin D3-occupied vitamin D receptors with cellular membrane acceptance sites. (1996) (62)
- Second messenger signaling in the regulation of collagenase production by osteogenic sarcoma cells. (1989) (61)
- Ligand trap for the activin type IIA receptor protects against vascular disease and renal fibrosis in mice with chronic kidney disease. (2016) (60)
- New concepts in renal osteodystrophy. (1998) (60)
- Bone morphogenetic protein-7 delays podocyte injury due to high glucose. (2007) (60)
- Cardiovascular risk in chronic kidney disease (CKD): the CKD-mineral bone disorder (CKD-MBD) (2010) (59)
- Protein transduction: delivery of Tat-GTPase fusion proteins into mammalian cells. (2001) (58)
- Calcium transport in canine renal basolateral membrane vesicles. Effects of parathyroid hormone. (1985) (56)
- The Mitogenic Effect of Parathyroid Hormone Is Associated with E2F‐Dependent Activation of Cyclin‐Dependent Kinase 1 (cdc2) in Osteoblast Precursors (1997) (55)
- Regulation of sodium-dependent phosphate transport in osteoclasts. (1997) (55)
- Bone morphogenetic protein-7: an anti-fibrotic morphogenetic protein with therapeutic importance in renal disease (2002) (55)
- Activin A stimulates IkappaB-alpha/NFkappaB and RANK expression for osteoclast differentiation, but not AKT survival pathway in osteoclast precursors. (2003) (54)
- The pathogenesis of vascular calcification in the chronic kidney disease mineral bone disorder: the links between bone and the vasculature. (2009) (54)
- Leupaxin Is a Critical Adaptor Protein in the Adhesion Zone of the Osteoclast (2003) (54)
- Branched-chain amino acid nitrogen transfer to alamine in vivo in dogs. Direct isotopic determination with [15N]leucine. (1980) (52)
- Parathyroid hormone depresses cytosolic pH and DNA synthesis in osteoblast-like cells. (1988) (52)
- Function and effect of bone morphogenetic protein‐7 in kidney bone and the bone‐vascular links in chronic kidney disease (2006) (51)
- Pathophysiology of the chronic kidney disease – mineral bone disorder (2015) (51)
- Androgens Enhance Male Urinary Tract Infection Severity in a New Model. (2016) (50)
- Cardiovascular risk factors in chronic kidney disease: does phosphate qualify? (2011) (50)
- The activin receptor is stimulated in the skeleton, vasculature, heart, and kidney during chronic kidney disease. (2018) (50)
- Antisense oligodeoxynucleotide inhibition of a swelling-activated cation channel in osteoblast-like osteosarcoma cells. (1996) (50)
- The BMP-7-Smad1/5/8 pathway promotes kidney repair after obstruction induced renal injury. (2011) (50)
- Bone Morphogenetic Protein 7 (BMP7) Gene Polymorphisms Are Associated With Inverse Relationships Between Vascular Calcification and BMD: The Diabetes Heart Study (2009) (49)
- Rapid quantitative bioassay of osteoinduction (2000) (49)
- Effect of intact parathyroid hormone on hepatic glucose release in the dog. (1979) (49)
- Admixture Mapping of Coronary Artery Calcified Plaque in African Americans With Type 2 Diabetes Mellitus (2013) (48)
- Metanephric osteopontin regulates nephrogenesis in vitro. (1997) (47)
- Sclerostin is positively associated with bone mineral density in men and women and negatively associated with carotid calcified atherosclerotic plaque in men from the African American-Diabetes Heart Study. (2014) (47)
- Osteopontin activation of c-src in human melanoma cells requires the cytoplasmic domain of the integrin alpha v-subunit. (1996) (46)
- Kidney-bone, bone-kidney, and cell-cell communications in renal osteodystrophy. (2004) (46)
- Colony Stimulating Factor‐1–Induced Osteoclast Spreading Depends on Substrate and Requires the Vitronectin Receptor and the c‐src Proto‐Oncogene (1998) (46)
- Effects of 1,25-dihydroxycholecalciferol on phosphate transport in vitamin D-deprived rats. (1984) (45)
- Ligand trap of the activin receptor type IIA inhibits osteoclast stimulation of bone remodeling in diabetic mice with chronic kidney disease. (2017) (45)
- Receptor-operated osteoclast calcium sensing. (2001) (44)
- Hormone‐Like Activity of Human Thrombin a (1986) (44)
- Increased Na+-H+ exchange in brush border vesicles from dogs with renal failure. (1982) (44)
- Engagement of the Osteoclast Integrin αvβ3 by Osteopontin Stimulates Phosphatidylinositol 3‐Hydroxyl Kinase Activity ab (1995) (43)
- Plasma Dickkopf1 (DKK1) concentrations negatively associate with atherosclerotic calcified plaque in African-Americans with type 2 diabetes. (2013) (43)
- The new kidney disease: improving global outcomes (KDIGO) guidelines - expert clinical focus on bone and vascular calcification. (2010) (43)
- Ca2+ priming during vitamin D-induced monocytic differentiation of a human leukemia cell line. (1988) (41)
- Mechanism of stimulation of renal phosphate transport by 1,25-dihydroxycholecalciferol. (1985) (41)
- Heterogeneous intracellular free calcium responses to parathyroid hormone correlate with morphology and receptor distribution in osteogenic sarcoma cells. (1992) (39)
- IL-1 activates the Na+/H+ antiport in a murine T cell. (1989) (39)
- The urinary response to an oral oxalate load in recurrent calcium stone formers. (2003) (39)
- Inulin: an inadequate marker of glomerular filtration rate in kidney donors and transplant recipients? (1979) (39)
- Effect of 25-hydroxycholecalciferol on calcium absorption in chronic renal disease. (1975) (38)
- Relationships between calcified atherosclerotic plaque and bone mineral density in African Americans with type 2 diabetes (2011) (38)
- The roles of the skeleton and phosphorus in the CKD mineral bone disorder. (2011) (37)
- Ischemic bowel disease following bilateral nephrectomy or renal transplant. (1977) (36)
- HDAC dependent transcriptional repression of Bmp-7 potentiates TGF-β mediated renal fibrosis in obstructive uropathy. (2014) (35)
- Invariant chain influences post-translational processing of HLA-DR molecules. (1991) (34)
- Significance of microbial contamination of stored cadaver kidneys. (1978) (34)
- Treatment of chronic tubulointerstitial disease: a new concept. (2002) (33)
- Membrane potential and cation content of osteoblast‐like cells (UMR 106) assessed by fluorescent dyes (1987) (33)
- Vascular smooth muscle cells in the pathogenesis of vascular calcification. (2009) (33)
- Polyphosphoinositides-dependent regulation of the osteoclast actin cytoskeleton and bone resorption (2004) (32)
- Bradykinin stimulates increased intracellular calcium in papillary collecting tubules of the rabbit. (1986) (32)
- X-linked hypophosphatemic rickets and the murine Hyp homologue. (1995) (32)
- Skeletal Casein Kinase Activity Defect in the HYP Mouse (1997) (31)
- Expression of DGCR8‐Dependent MicroRNAs Is Indispensable for Osteoclastic Development and Bone‐Resorbing Activity (2014) (30)
- Left Ventricular Mass Progression despite Stable Blood Pressure and Kidney Function in Stage 3 Chronic Kidney Disease (2014) (30)
- Clinical utility of radioimmunoassays for parathyroid hormone (1980) (30)
- Genomic organization of a human cystine transporter gene (SLC3A1) and identification of novel mutations causing cystinuria. (1997) (30)
- Proprotein convertases regulate activity of prostate epithelial cell differentiation markers and are modulated in human prostate cancer cells (2003) (30)
- Parathyroid hormone inhibition of phosphate transport in renal brush border vesicles from phosphate-depleted dogs. (1981) (30)
- Pathophysiology of renal osteodystrophy (2000) (30)
- Disassociation of the macrophage-maturational effects of vitamin D from respiratory burst priming. (1991) (29)
- Current concepts of the metabolism and radioimmunoassay of parathyroid hormone. (1982) (29)
- Plasma FGF23 and Calcified Atherosclerotic Plaque in African Americans with Type 2 Diabetes Mellitus (2015) (29)
- Phosphorylation of renal brush-border membrane vesicles. Effect on calcium uptake and membrane content of polyphosphoinositides. (1983) (28)
- Relationships between serum adiponectin and bone density, adiposity and calcified atherosclerotic plaque in the African American-Diabetes Heart Study. (2013) (27)
- Decreased luminal membrane transport of phosphate in chronic renal failure. (1982) (27)
- The Kidney-Vascular-Bone Axis in the Chronic Kidney Disease-Mineral Bone Disorder. (2016) (27)
- Stimulation of transient elevations in cytosolic Ca2+ is related to inhibition of Pi transport in OK cells. (1990) (26)
- Stimulation of calcium uptake by parathyroid hormone in renal brush-border membrane vesicles. Relationship to membrane phosphorylation. (1983) (26)
- SIRT6 deficiency culminates in low-turnover osteopenia. (2015) (26)
- RGS4, a GTPase activator, improves renal function in ischemia-reperfusion injury. (2011) (25)
- Hormonal regulation of gluconeogenesis in cultured proximal tubular cells: role of cytosolic calcium. (1987) (25)
- In vivo transplantation of neonatal ovine neocartilage allografts: determining the effectiveness of tissue transglutaminase. (2010) (24)
- Pathogenesis of nephrolithiasis post-partial ileal bypass surgery: case-control study. The POSCH Group. (1991) (24)
- Phosphate transport in osteoclasts: a functional and immunochemical characterization. (1996) (24)
- Free myo-Inositol in Canine Kidneys: Selective Concentration in the Renal Medulla 1 (1982) (24)
- Cyclic AMP-dependent and calcium-dependent signals in parathyroid hormone function (1990) (24)
- Renal osteodystrophy. (1997) (24)
- Alpha1‐adrenergic stimulation and cytoplasmic free calcium concentration in cultured renal proximal tubular cells: Evidence for compartmentalization of quin‐2 and fura‐2 (1986) (24)
- Endogenous BMP-7 is a critical molecular determinant of the reversibility of obstruction-induced renal injuries. (2011) (24)
- Cytoplasmic calcium in individual proximal tubular cells in culture. (1986) (23)
- 1,25-Dihydroxycholecalciferol stimulates renal phosphate transport by directly altering membrane phosphatidylcholine composition. (1987) (23)
- Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study (2012) (23)
- New approaches to delay the progression of chronic renal failure. (2002) (22)
- Desensitization of calcium messenger system in parathyroid hormone-stimulated opossum kidney cells. (1993) (21)
- PTH (parathyroid hormone) elevates inositol polyphosphates and diacylglycerol in a rat osteoblast-like cell line (1988) (21)
- Effect of 1,25-dihydroxyvitamin D3 on phospholipid composition of rat renal brush border membrane. (1985) (21)
- Connections between vascular calcification and progression of chronic kidney disease: therapeutic alternatives. (2005) (20)
- Binding of osteopontin to the osteoclast integrin αvβ3 (2005) (20)
- Thrombin chemotactic stimulation of HL‐60 cells: Studies on thrombin responsiveness as a function of differentiation (1987) (20)
- Tetracycline fluorescence in uremic and primary hyperparathyroid bone. (1977) (20)
- Regulation of alphaVbeta3 and alphaVbeta5 integrins by dexamethasone in normal human osteoblastic cells. (2000) (20)
- Effects of glucose and parathyroid hormone on the renal handling of myoinositol by isolated perfused dog kidneys. (1979) (19)
- Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis (2017) (18)
- Exogenous BMP7 in aortae of rats with chronic uremia ameliorates expression of profibrotic genes, but does not reverse established vascular calcification (2018) (18)
- Vitamin D metabolites stimulate phosphatidylcholine transfer to renal brush-border membranes. (1986) (18)
- The effect of 5,6-trans vitamin D3 on calcium absorption in chronic renal disease. (1975) (18)
- Impairment of the collagenase-3 endocytotic receptor system in cells from patients with osteoarthritis. (2003) (18)
- Regulation of cytosolic calcium by parathyroid hormone and oscillations of cytosolic calcium in fibroblasts from normal and pseudohypoparathyroid patients. (1991) (17)
- Cytoplasmic pH regulation in canine renal proximal tubule cells. (1987) (17)
- Altered osteoblast gluconeogenesis in X-linked hypophosphatemic mice is associated with a depressed intracellular pH (1995) (17)
- Clinical phenotype of APOL1 nephropathy in young relatives of patients with end-stage renal disease (2015) (16)
- New discoveries in the pathogenesis of renal osteodystrophy (2006) (15)
- Saccharomyces fungemia. (1970) (15)
- Androgen exposure potentiates formation of intratubular communities and renal abscesses by Escherichia coli. (2018) (15)
- Rac is Essential in the Transformation of Endothelial Cells by Polyoma Middle T (2000) (15)
- Transcytosis in cultured proximal tubular cells (1986) (15)
- Signal regulatory protein alpha initiates cachexia through muscle to adipose tissue crosstalk (2019) (14)
- Hormonal modulation of cytoplasmic calcium concentration in renal tubular epithelium. (1988) (14)
- Characterization of phospholipase C activity of the plasma membrane and cytosol of an osteoblast-like cell line. (1989) (14)
- Effect of biological activity of PTH on its peripheral metabolism in the rat. (1987) (14)
- Sotatercept Safety and Effects on Hemoglobin, Bone, and Vascular Calcification (2019) (14)
- AN EVALUATION OF A NEW AND EFFECTIVE PHOSPHORUS BINDING AGENT (1973) (14)
- Chapter 73. Chronic Kidney Disease Mineral Bone Disorder (CKD‐MBD) (2009) (13)
- Bone Mineral Density and Progression of Subclinical Atherosclerosis in African-Americans With Type 2 Diabetes. (2016) (13)
- Voltage dependent calcium channel expression in isolated osteoclasts. (1989) (13)
- Characterization of a (Ca2+ + Mg2+)-ATPase system in the osteoblast plasma membrane. (1988) (13)
- Pathophysiology of Chronic Kidney Disease Mineral Bone Disorder (CKD‐MBD) (2013) (13)
- Evidence for a prostaglandin-mediated bone resorptive mechanism in subjects with fasting hypercalciuria (1988) (12)
- The effects of extracellular calcium and epinephrine on cytosolic-free calcium in single rat adipocytes. (1992) (12)
- Current concepts of parathyroid hormone and vitamin D metabolism: perturbations in chronic renal disease. (1975) (12)
- Parathyroid hormone-induced changes of the brush border topography and cytoskeleton in cultured renal proximal tubular cells (2005) (11)
- Does strict phosphorus control precipitate renal osteomalacia? (1986) (11)
- Parathyroid Hormone: Alterations in Chronic Renal Failure (1984) (10)
- Na+-Ca2+ exchange and calcium permeability in canine basolateral membrane vesicles: the effects of dibutyryl cAMP and specific inhibitors. (1988) (10)
- Stimulation of phosphatidylcholine biosynthesis in diabetic hypertrophic kidneys. (1987) (9)
- Volume regulatory decrease in UMR-106.01 cells is mediated by specific α1 subunits of L-type calcium channels (2007) (8)
- The role of phosphate and other factors on the pathogenesis of renal osteodystrophy. (1977) (8)
- Osteoporosis and cardiovascular disease: lessons from chronic kidney disease. (2008) (8)
- An Arg-Gly-Asp peptide stimulates Ca2+ efflux from osteoclast precursors through a novel mechanism. (1994) (8)
- Regulation of skeletal remodeling by parathyroid hormone. (1991) (8)
- Effect of parathyroid hormone on phospholipid metabolism. (1982) (7)
- Laboratory Investigations The Integrin avb3 and CD44 Regulate the Actions of Osteopontin on Osteoclast Motility (2002) (7)
- SIGNAL TRANSDUCTION IN OSTEOBLASTS AND OSTEOCLASTS (1993) (7)
- Parathormone levels after subtotal and total (autotransplantation) parathyroidectomy for secondary hyperparathyroidism. (1980) (7)
- Androgen-Influenced Polarization of Activin A-Producing Macrophages Accompanies Post-pyelonephritic Renal Scarring (2020) (6)
- Renal Adaptation to Dietary Phosphate Restriction in Rats: Interactions With Insulin and Calcitriol (1991) (6)
- The benefits of evaluation of the patient with recurrent or multiple calcium stones. (1979) (5)
- Uptake of Pi in brush border vesicles after release of unilateral ureteral obstruction. (1982) (5)
- Regulation of phosphate transport. (1997) (5)
- Localization of ral, a small Mr GTP-binding protein, to collecting duct cells in bovine and rat kidney. (1991) (5)
- Pathophysiology of Nephrolithiasis (1983) (5)
- Demonstration of a direct effect of atrial natriuretic factor on epithelium: study in cultured pig kidney cells. (1987) (5)
- Correction: Renal scar formation and kidney function following antibiotic-treated murine pyelonephritis (doi: 10.1242/dmm.030130) (2018) (4)
- Abnormalities in parathyroid hormone secretion in primary and secondary hyperparathyroidism. (1984) (4)
- Identification and localization of pertussis toxin-sensitive GTP-binding proteins in bovine kidney glomeruli. (1991) (4)
- A dihydropyridine-sensitive calcium channel in rodent osteoblastic cells (2007) (4)
- Crosstalk between kidney and bone - Bench to bedside. (2017) (4)
- Cardiovascular risk factors in chronic kidney disease: does phosphate qualify? (2011) (4)
- Neurotensin binding to human embryonic lung fibroblasts. (1994) (4)
- Chronic Kidney Disease–Mineral and Bone Disorders (2020) (4)
- Monitoring cytosolic calcium in parathyroid hormone target cells: Osteoblasts and renal epithelia (1991) (4)
- Proximal Tubule Transport (1984) (4)
- The biochemical modifications of the brush border membrane induced by vitamin D and parathyroid hormone in their actions on phosphate transport. (1984) (4)
- Parathyroid Hormone Receptor Coupling to Phospholipase C is an Alternate Pathway of Signal Transduction in the Bone and Kidney (1991) (4)
- Fibroblast growth factor‐23 and chronic allograft injury in pediatric renal transplant recipients: a Midwest Pediatric Nephrology Consortium study (2016) (3)
- The chronic kidney disease-mineral bone disorder (CKD-MBD) and vascular calcification (2012) (3)
- New Insights into Aging and Renal Osteodystrophy (2000) (3)
- Dibutryladenosine 3',5'-cyclic monophosphate (dBcAMP) does not mimic the action of parathyroid hormone (PTH) on canine proximal tubular basolateral membrane Na+:Ca2+. (1986) (3)
- 1,25-Dihydroxycholecalciferol and macrophage differentiation with aging (1990) (3)
- THE PATHOGENESIS OF VASCULAR CALCIFICATION IN THE CHRONIC KIDNEY DISEASE MINERAL BONE DISORDER (CKD- MBD): (2009) (2)
- Intracellular acidification induces decrease of cytosolic calcium in isolated osteoclasts. (1989) (2)
- Pathophysiology of Acid-Base Metabolism (1983) (2)
- Exaggerated Response of the Hyper-Oxaluric Stone Former to an Oxalate Load Test at Initial Metabolic Evaluation (1994) (2)
- Ca2+ uptake by endoplasmic reticulum of renal cortex. II. Effects of uninephrectomy and parathyroidectomy (1992) (2)
- Effects of parathyroid hormone on glucose production by the liver. (1980) (2)
- HORMONAL EFFECTS ON myo-INOSITOL METABOLISM IN THE DOG 1 (1978) (2)
- Chapter 7 – Disorders of Phosphate Homeostasis (1998) (2)
- Renal injury by companion kidney during hypothermic pulsatile perfusion. (1978) (2)
- Post-transplant osteodystrophy in the era of the K/DOQI guidelines (2003) (2)
- Podosome expression in osteoclasts: influence of high extracellular calcium concentration. (1989) (2)
- Parathyroid hormone: Secretion, metabolism, and biologic actions (1981) (2)
- New pathogenic insights inform therapeutic target development for renal osteodystrophy. (2019) (2)
- Parathyroid hormone (PTH) metabolism in chronic renal disease (CRD). (1975) (2)
- Interactions between liver and parathyroid hormone. (1982) (1)
- Calcium as a Mediator of the Physiologic and Pathophysiologic Effects of Parathyroid Hormone (1984) (1)
- Overview of Phosphorus Homeostasis (2017) (1)
- Oxalate Transport Across The Renal Papilla: Implications in Sites and Mechanism of Initial Kidney Stone Formation (1994) (1)
- Regulation of podosomes by intracellular pH in avian osteoclasts. (1989) (1)
- Recent progress in signal transduction related to bone remodeling and aging. (1995) (1)
- Hepatic metabolism of parathyroid hormone. (1982) (1)
- Disorders of Mineral and Bone Metabolism in Chronic Kidney Disease (2015) (1)
- The role of the skeleton in the pathogenesis of vascular calcification in the chronic kidney disease–mineral bone disorder (2010) (1)
- Inositol Lipids in Cell Signaling by Parathyroid Hormone (1989) (1)
- Ca2+ uptake by endoplasmic reticulum of renal cortex. I. Ionic requirements and regulation in vitro (1992) (1)
- Effects of Phorbol Ester, Cyclic Nucleotides, and Ionomycin on Ion Transport and Brush‐Border Topography in Cultured Renal Proximal Tubular Cells (1987) (1)
- The uptake of parathyroid hormone by isolated perfused bone: possible significance of peripheral hormone metabolism. (1978) (1)
- Angiotensin II binding to human embryonic lung fibroblasts causes transient changes in cytosolic calcium and promotes fibrin gel contraction. (1994) (1)
- The direct effect of 1,25-dihydroxycholecalciferol on membrane phospholipid composition and phosphate transport. (1986) (1)
- RGS4 Prevents the Development of Renal Dysfunction in Response to Ischemia/Reperfusion Injury (2011) (1)
- New insights related to aging and renal osteodystrophy. (1999) (1)
- Activation of the [Ca2+]i message system by parathyroid-hormone-related/protein in osteoblastic cells. (1990) (1)
- The Prospect of a Novel Therapeutic, Bone Morphogenetic Protein-7, in Diabetic Nephropathy (2006) (1)
- FP406THE ROLE OF ACTIVIN SIGNALING IN THE PATHOGENESIS OF RENAL OSTEODYSTROPHY OF CKD-MBD (2015) (0)
- Recent Progress in Signal Transduction Related to Bone Remodeling and Aging (2014) (0)
- Membrane phospholipid pl metabolism and phosphate transport in x linked hypophosphatemia hyp y (1987) (0)
- Acidosis in CKD May Affect Mineralization of Newly Formed Bone According to HR-pQCT and Quantitative Back Scatter Electron Imaging. (2023) (0)
- Mechanisms of ion transport regulation by parathyroid hormone: cAMP/Ca2+/calmodulin and phospholipid dependent phosphorylation. (1986) (0)
- FGF23—an established master regulator of phosphate metabolism (2021) (0)
- Consultant List (2002) (0)
- Acknowledgement to the Reviewers (2015) (0)
- PTH Control of Osteoblastic Function (1989) (0)
- Hyperphosphatemia. (2019) (0)
- Bone matrix inhibits csf-1 induced osteoclast spreading (1995) (0)
- Parathyroid hormone (PTH) induced activation of Ca2+/calmodulin dependent protein kinase (PK) in canine basolateral cell membrane vesicles (BLMV) in vitro (1984) (0)
- Supplementary Material for: Plasma FGF23 and Calcified Atherosclerotic Plaque in African Americans with Type 2 Diabetes Mellitus (2016) (0)
- Non-lethal oxidative insult to cultured renal tubular cells : autocrine stimulation of proliferation (1992) (0)
- BONE MORPHOGENIC PROTEIN-7 (BMP-7) PROMOTES RENAL RECOVERY FOLLOWING THE RELIEF OF URETERAL OBSTRUCTION (2008) (0)
- Acute parathyroid hormone stimulation of myo inositol release by isolated perfused dog kidneys (1976) (0)
- Contents Vol. 42, 2015 (2016) (0)
- Studies on a new and effective phosphate binding agent (1973) (0)
- THE CRITICAL FUNCTION OF OSTEOPONTIN IN [alpha]v[beta]3 SIGNALING (2002) (0)
- Mechanical strain induces mineralization of the osteoblastic extracellular matrix through the alphaVbeta3 integrin (1999) (0)
- Pathophysiology of the CKD-MBD Syndrome (2020) (0)
- Pathophysiology of The Chronic Kidney Disease–Mineral Bone Disorder (2020) (0)
- Metabolism of intact parathyroid hormone (PTH) in the dog (1979) (0)
- Effects of parathyroid hormone (PTH) on renal myo inositol (MI) metabolism. Relationship to ion transport (1977) (0)
- Phytohemagglutinin rapidly lyses S49 T-lymphoma cells and the cytotoxicity is not mediated by generation of cAMP or increase in cytosolic calcium. (1990) (0)
- Cytosolic calcium concentration in a single proximal tubule cell ptc during anoxia and re oxygenation (1987) (0)
- Metabolism of parathyroid hormone (PTH) by the isolated canine kidney (1975) (0)
- Osteopontin. (2020) (0)
- Further studies on the effect of parathyroid hormone (PTH) on myoinositol metabolism and ion transport (1978) (0)
- The uptake of immunoreactive parathyroid hormone by peripheral organs. (1980) (0)
- The effect of extracellular K on osteoclast function (1990) (0)
- MOLECULAR MECHANISMS OF INTERACTION BETWEEN [alpha]V[beta]3 AND CD44 SIGNALING (2002) (0)
- Buyer beware! Doctor be aware!—Answers (2013) (0)
- SP645QUANTITATIVE COMPUTED TOMOGRAPHY RESULTS FOR BONE MASS AND ABDOMINAL AORTIC VASCULAR CALCIFICATION IN HEMODIALYSIS SUBJECTS TREATED WITH ESCALATING DOSE LEVELS OF SOTATERCEPT: INTERIM ANALYSIS OF ACE-011-REN-001 (2015) (0)
- Parathyroid hormone (PTH) induced turnover of myoinositol in isolated perfused dog kidneys (1976) (0)
- 282 BMP-7 IS REQUIRED FOR THE REPAIR OF RENAL INJURIES RESULTING FROM OBSTRUCTIVE UROPATHIES (2010) (0)
- Semiquantitative estimation of phosphatase activity in the Sephadex layer (1966) (0)
- The pathophysiology of the chronic kidney disease-mineral bone disorder: synopsis of a symposium at the Sun Valley Musculoskeletal Biology Workshop (2013) (0)
- On the genesis of renal osteodystrophy (1982) (0)
- KEY PATHOGENIC COMPONENTS OF THE CHRONIC KIDNEY DISEASE – MINERAL BONE DISORDER Dickkopf (2015) (0)
- 726 BMP-7 SERVES AS A PROGNOSTIC BIOMARKER IN EVALUATING URETEROPELVIC JUNCTION (UPJ) OBSTRUCTIONS (2012) (0)
- Adverse effect of ischemic companion kidney during ex vivo renal perfusion. (1977) (0)
- Regulation of renal phosphate reabsorption: concepts in evolution (1987) (0)
- Metabolism of Parathyroid Hormone and Interpretation of Radioimmunoassays for PTH (1985) (0)
- Engagement of the osteoclast integrin alpha v beta 3 by osteopontin stimulates phosphatidylinositol 3-hydroxyl kinase activity. (1995) (0)
- Buyer beware! doctor be aware!: Questions (2013) (0)
- Immunological causes of sterility. (1970) (0)
- Updates in the chronic kidney disease-mineral bone disorder show the role of osteocytic proteins, a potential mechanism of the bone—Vascular paradox, a therapeutic target, and a biomarker (2023) (0)
- PTH stimulation of collagenase in osteoblastlike cells: Role of second messengers (1987) (0)
- 266 THE HDAC-DEPENDENT SUPPRESSION OF BMP-7 TRANSCRIPTION CONTRIBUTES TO THE PATHOGENESIS OF OBSTRUCTIVE UROPATHIES (2011) (0)
- Studieson liver function. I. Synthesis of hippuricacid by rat liver slices after liver injury. (1960) (0)
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What Schools Are Affiliated With Keith A. Hruska?
Keith A. Hruska is affiliated with the following schools:
