Kenneth D. Brandt

Kenneth D. Brandt's AcademicInfluence.com Rankings

Kenneth D. Brandt

Philosophy

#4576

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#7150

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#1987

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#2876

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Philosophy

Kenneth D. Brandt's Degrees

Doctorate Medicine University of California, San Francisco

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Kenneth D. Brandt's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. (1986) (6249)
OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. (2008) (2699)
Osteoarthritis: New Insights. Part 1: The Disease and Its Risk Factors (2000) (2404)
The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand. (1990) (1930)
OARSI recommendations for the management of hip and knee osteoarthritis: part III: Changes in evidence following systematic cumulative update of research published through January 2009. (2010) (1671)
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. (2006) (1236)
The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hip. (1991) (1069)
Guidelines for the medical management of osteoarthritis (1995) (870)
OARSI recommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treatment guidelines and systematic review of current research evidence. (2007) (834)
Guidelines for the medical management of osteoarthritis. Part II. Osteoarthritis of the knee. American College of Rheumatology. (1995) (833)
Recommendations for a core set of outcome measures for future phase III clinical trials in knee, hip, and hand osteoarthritis. Consensus development at OMERACT III. (1997) (730)
Reduced quadriceps strength relative to body weight: a risk factor for knee osteoarthritis in women? (1998) (604)
Comparison of an antiinflammatory dose of ibuprofen, an analgesic dose of ibuprofen, and acetaminophen in the treatment of patients with osteoarthritis of the knee. (1991) (600)
Design and conduct of clinical trials in patients with osteoarthritis : Recommendations from a task force of the Osteoarthritic Research Society (1996) (508)
Yet more evidence that osteoarthritis is not a cartilage disease (2006) (412)
OARSI-FDA initiative: defining the disease state of osteoarthritis. (2011) (336)
Osteoarthritic changes in canine articular cartilage, subchondral bone, and synovium fifty-four months after transection of the anterior cruciate ligament. (2010) (331)
Development and reversal of a proteoglycan aggregation defect in normal canine knee cartilage after immobilization. (1979) (297)
Radiographic grading of the severity of knee osteoarthritis: relation of the Kellgren and Lawrence grade to a grade based on joint space narrowing, and correlation with arthroscopic evidence of articular cartilage degeneration. (2010) (291)
Guidelines for the medical management of osteoarthritis. Part I. Osteoarthritis of the hip. American College of Rheumatology. (1995) (276)
Effects of strength training on the incidence and progression of knee osteoarthritis. (2006) (273)
A longitudinal study of subchondral plate and trabecular bone in cruciate-deficient dogs with osteoarthritis followed up for 54 months. (1993) (267)
Effects of static and cyclic compressive loading on articular cartilage plugs in vitro. (1984) (263)
Guidelines for the medical management of osteoarthritis. II: Osteoarthritis of the knee (1995) (263)
Effects of doxycycline on progression of osteoarthritis: results of a randomized, placebo-controlled, double-blind trial. (2005) (261)
Joint motion in the absence of normal loading does not maintain normal articular cartilage. (1980) (244)
A clinical analysis of the course and prognosis of forty-two patients with amyloidosis. (1968) (236)
Relationship between arthroscopic evidence of cartilage damage and radiographic evidence of joint space narrowing in early osteoarthritis of the knee. (1991) (229)
Reduction of the severity of canine osteoarthritis by prophylactic treatment with oral doxycycline. (1992) (223)
Anterior (cranial) cruciate ligament transection in the dog: a bona fide model of osteoarthritis, not merely of cartilage injury and repair. (1991) (213)
Intraarticular injection of hyaluronan as treatment for knee osteoarthritis: what is the evidence? (2000) (202)
Guidelines for testing slow acting drugs in osteoarthritis. (1994) (196)
Design and conduct of clinical trials in patients with osteoarthritis: recommendations from a task force of the Osteoarthritis Research Society. Results from a workshop. (1996) (196)
Measurement of radiographic joint space width in the tibiofemoral compartment of the osteoarthritic knee: comparison of standing anteroposterior and Lyon schuss views. (2003) (182)
Synovial inflammation in patients with early osteoarthritis of the knee. (1990) (180)
Specificity of inhibition of matrix metalloproteinase activity by doxycycline: relationship to structure of the enzyme. (1999) (177)
Treatment of septic arthritis (1975) (167)
Quadriceps strength in women with radiographically progressive osteoarthritis of the knee and those with stable radiographic changes. (1999) (156)
Experimental assessment by high frequency ultrasound of articular cartilage thickness and osteoarthritic changes. (1995) (152)
Running inhibits the reversal of atrophic changes in canine knee cartilage after removal of a leg cast. (1981) (151)
Efficacy and Safety of Intraarticular Sodium Hyaluronate in Knee Osteoarthritis (2001) (146)
Apparent avascular necrosis of the hip: appearance and spontaneous resolution of MR findings in renal allograft recipients. (1991) (139)
Which is the best radiographic protocol for a clinical trial of a structure modifying drug in patients with knee osteoarthritis? (2002) (135)
Effects of some nonsteroidal antiinflammatory drugs on proteoglycan metabolism and organization in canine articular cartilage. (1980) (134)
Neurogenic acceleration of degenerative joint lesions. (1985) (133)
Reduction of joint pain in patients with knee osteoarthritis who have received monthly telephone calls from lay personnel and whose medical treatment regimens have remained stable. (1992) (131)
Infectious complications of cyclophosphamide treatment for vasculitis. (1989) (126)
Gait alterations in dogs after transection of the anterior cruciate ligament. (1989) (123)
Tidal irrigation as treatment for knee osteoarthritis: a sham-controlled, randomized, double-blinded evaluation. (2002) (123)
OARSI-OMERACT definition of relevant radiological progression in hip/knee osteoarthritis. (2009) (119)
Acute arthritis caused by gram-negative bacilli: a clinical characterization. (1974) (116)
Effect of alignment of the medial tibial plateau and x-ray beam on apparent progression of osteoarthritis in the standing anteroposterior knee radiograph. (2001) (114)
A 2-year randomised, double-blind, placebo-controlled, multicentre study of oral selective iNOS inhibitor, cindunistat (SD-6010), in patients with symptomatic osteoarthritis of the knee (2012) (111)
Treatment of knee osteoarthritis: relationship of clinical features of joint inflammation to the response to a nonsteroidal antiinflammatory drug or pure analgesic. (1992) (108)
Triamcinolone hexacetonide protects against fibrillation and osteophyte formation following chemically induced articular cartilage damage. (1985) (104)
Effects of self-care education on the health status of inner-city patients with osteoarthritis of the knee. (1997) (103)
Synovitis and osteoarthritic changes in canine articular cartilage after anterior cruciate ligament transection. Effect of surgical hemostasis. (1990) (103)
Composition and glycosaminoglycan metabolism of articular cartilage from habitually loaded and habitually unloaded sites. (1986) (103)
Marked suppression by salicylate of the augmented proteoglycan synthesis in osteoarthritic cartilage. (1980) (101)
Migrainous phenomena in systemic lupus erythematosus. (1978) (101)
Diacerhein treatment reduces the severity of osteoarthritis in the canine cruciate-deficiency model of osteoarthritis. (1999) (99)
Change in regional cartilage morphology and joint space width in osteoarthritis participants versus healthy controls: a multicentre study using 3.0 Tesla MRI and Lyon–Schuss radiography (2008) (97)
Neurogenic acceleration of osteoarthrosis. The effects of previous neurectomy of the articular nerves on the development of osteoarthrosis after transection of the anterior cruciate ligament in dogs. (1992) (96)
Knee pain reduces joint space width in conventional standing anteroposterior radiographs of osteoarthritic knees. (2002) (95)
The mechanism of action of nonsteroidal antiinflammatory drugs. (1991) (95)
Effects of nonsteroidal anti-inflammatory drugs on chondrocyte metabolism in vitro and in vivo. (1987) (94)
Head-to-head comparison of the Lyon Schuss and fixed flexion radiographic techniques. Long-term reproducibility in normal knees and sensitivity to change in osteoarthritic knees (2008) (94)
Oral administration of doxycycline reduces collagenase and gelatinase activities in extracts of human osteoarthritic cartilage. (1998) (92)
Immobilization of the knee prevents osteoarthritis after anterior cruciate ligament transection. (1982) (91)
Activation of recombinant human neutrophil procollagenase in the presence of doxycycline results in fragmentation of the enzyme and loss of enzyme activity. (1996) (90)
Doxycycline inhibits type XI collagenolytic activity of extracts from human osteoarthritic cartilage and of gelatinase. (1991) (89)
Finger joint force minimization in pianists using optimization techniques. (1993) (88)
Is conventional radiography suitable for evaluation of a disease-modifying drug in patients with knee osteoarthritis? (1997) (88)
In vivo effect of aspirin on canine osteoarthritic cartilage. (1983) (85)
Treatment of septic arthritis: comparison of needle aspiration and surgery as initial modes of joint drainage. (1975) (85)
Serial kinematic analysis of the unstable knee after transection of the anterior cruciate ligament: Temporal and angular changes in a canine model of osteoarthritis (1994) (85)
Effect of salicylate on proteoglycan metabolism in normal canine articular cartilage in vitro. (1979) (83)
Workshop on etiopathogenesis of osteoarthritis, Warrenton VA, July 21-25, 1985: reasearch recommendations arising from the workshop (1986) (82)
Effect of intraarticular hyaluronan injection in experimental canine osteoarthritis. (1998) (82)
Commentary: is it useful to subset "primary" osteoarthritis? A critique based on evidence regarding the etiopathogenesis of osteoarthritis. (2009) (81)
Use of the plasma stromelysin (matrix metalloproteinase 3) concentration to predict joint space narrowing in knee osteoarthritis. (2005) (80)
Educational Program for Nursing Home Physicians and Staff to Reduce Use of Non-Steroidal Anti-Inflammatory Drugs Among Nursing Home Residents: A Randomized Controlled Trial (2001) (79)
Comparison of general internists, family physicians, and rheumatologists managing patients with symptoms of osteoarthritis of the knee. (1997) (77)
Transection of the anterior cruciate ligament in the dog: a model of osteoarthritis. (1991) (77)
Educational Program for Physicians to Reduce Use of Non-Steroidal Anti-Inflammatory Drugs Among Community-Dwelling Elderly Persons: A Randomized Controlled Trial (2001) (74)
Effects of a bisphosphonate on bone histomorphometry and dynamics in the canine cruciate deficiency model of osteoarthritis. (1999) (74)
Assessment of the radioanatomic positioning of the osteoarthritic knee in serial radiographs: comparison of three acquisition techniques. (2006) (73)
Development of clinical criteria for osteoarthritis. (1987) (72)
A comparison of lower extremity muscle strength, obesity, and depression scores in elderly subjects with knee pain with and without radiographic evidence of knee osteoarthritis. (2000) (71)
Reduced utilization and cost of primary care clinic visits resulting from self-care education for patients with osteoarthritis of the knee. (1999) (71)
Immunoglobulins and amyloidosis. An immunologic study of sixty-two patients with biopsy-proved disease. (1972) (70)
Detection of radiographic joint space narrowing in subjects with knee osteoarthritis: longitudinal comparison of the metatarsophalangeal and semiflexed anteroposterior views. (2003) (70)
Efficacy and safety of intraarticular sodium hyaluronate in knee osteoarthritis. ORTHOVISC Study Group. (2001) (68)
Severity of medial meniscus damage in the canine knee after anterior cruciate ligament transection. (2002) (67)
Rapidly progressive Charcot arthropathy following minor joint trauma in patients with diabetic neuropathy. (1990) (67)
Pilot study of the effects of a heat-retaining knee sleeve on joint pain, stiffness, and function in patients with knee osteoarthritis. (2004) (65)
Response of joint structures to inactivity and to reloading after immobilization. (2003) (64)
Relationship between matrix proteoglycan content and the effects of salicylate and indomethacin on articular cartilage. (1983) (62)
Lessons learned from nine clinical trials of disease-modifying osteoarthritis drugs. (2005) (62)
Prevalence of cartilage shards in synovium and their association with synovitis in patients with early and endstage osteoarthritis. (1992) (62)
Field test of the reproducibility of automated measurements of medial tibiofemoral joint space width derived from standardized knee radiographs. (1999) (61)
Evidence of the validity of the Arthritis Impact Measurement Scales. (1987) (61)
Immobilization ameliorates chemically-induced articular cartilage damage. (1984) (60)
Even low-grade synovitis significantly accelerates the clearance of protein from the canine knee. Implications for measurement of synovial fluid "markers" of osteoarthritis. (1995) (60)
Pitfalls in the accurate measurement of joint space narrowing in semiflexed, anteroposterior radiographic imaging of the knee. (2004) (60)
A randomized, double blind, placebo controlled trial of intravenous loading with S-adenosylmethionine (SAM) followed by oral SAM therapy in patients with knee osteoarthritis. (1994) (59)
Effects of diacerhein in an accelerated canine model of osteoarthritis. (1997) (59)
Design and conduct of clinical trials in osteoarthritis: preliminary recommendations from a task force of the Osteoarthritis Research Society. (1997) (59)
Use of resting splints by patients with rheumatoid arthritis. (1981) (59)
Insights into the Natural History of Osteoarthritis Provided by the Cruciate‐Deficient Dog (1994) (58)
Aggregation of cartilage proteoglycans. II Evidence for the presence of a hyaluronate-binding region on proteoglycans from osteoarthritic cartilage. (1976) (56)
Motion for debate: osteoarthritis clinical trials have not identified efficacious therapies because traditional imaging outcome measures are inadequate. (2013) (56)
The importance of nonpharmacologic approaches in management of osteoarthritis. (1998) (56)
Aspirin aggravates the degeneration of canine joint cartilage caused by immobilization. (1982) (56)
Effects of salicylates and other nonsteroidal anti-inflammatory drugs on articular cartilage. (1984) (56)
Hypertrophic repair of canine articular cartilage in osteoarthritis after anterior cruciate ligament transection. (1991) (56)
Analysis of education-support groups for patients with rheumatoid arthritis. (1983) (54)
Superiority of the Lyon schuss view over the standing anteroposterior view for detecting joint space narrowing, especially in the lateral tibiofemoral compartment, in early knee osteoarthritis (2007) (53)
Studies of immune deposits in synovial membranes and corresponding synovial fluids. (1968) (52)
In vitro protein binding of diclofenac sodium in plasma and synovial fluid. (1987) (51)
Acetaminophen, like conventional NSAIDs, may reduce synovitis in osteoarthritic knees. (2006) (51)
The Role of Analgesics in the Management of Osteoarthritis Pain (2000) (50)
Erratum: Guidelines for testing slow acting drugs in osteoarthritis (Journal of Rheumatology (1994) (Suppl 41) 21: (65-71)) (1994) (50)
Cerebral disorders of vision in systemic lupus erythematosus. (1975) (49)
Enhanced extractability of articular cartilage protoglycans in osteoarthrosis. (1974) (48)
Hyaluronate-binding by proteoglycans. Comparison of mildly and severely osteoarthritic regions of human femoral cartilage. (1976) (48)
Gonococcal arthritis. Clinical features correlated with blood, synovial fluid and genitourinary cultures. (1974) (47)
Subregional femorotibial cartilage morphology in women--comparison between healthy controls and participants with different grades of radiographic knee osteoarthritis. (2009) (46)
Severity of knee pain does not predict a better response to an antiinflammatory dose of ibuprofen than to analgesic therapy in patients with osteoarthritis. (2001) (46)
Associations between joint space narrowing and molecular markers of collagen and proteoglycan turnover in patients with knee osteoarthritis. (2006) (45)
Field test of the reproducibility of the semiflexed metatarsophalangeal view in repeated radiographic examinations of subjects with osteoarthritis of the knee. (2002) (45)
Identification of a high-molecular-weight (> 400 000) protein in hyaline cartilage (1984) (45)
Interaction of proteoglycans with the pericellular (1 alpha, 2 alpha, 3 alpha) collagens of cartilage. (1985) (45)
Exercise increases osteophyte formation and diminishes fibrillation following chemically induced articular cartilage injury. (1984) (44)
Herniation of mitral leaflets in the Ehlers-Danlos syndrome. (1975) (44)
What is important in treating osteoarthritis? Whom should we treat and how should we treat them? (2003) (44)
Putting Some Muscle into Osteoarthritis (1997) (44)
Is knee radiography useful for studying the efficacy of a disease-modifying osteoarthritis drug in humans? (2003) (43)
Effect of intraarticular hyaluronan injection on vertical ground reaction force and progression of osteoarthritis after anterior cruciate ligament transection. (2005) (43)
Sensory nerves only temporarily protect the unstable canine knee joint from osteoarthritis. Evidence that sensory nerves reprogram the central nervous system after cruciate ligament transection. (1993) (43)
Views of patients and providers regarding the importance of various aspects of an arthritis treatment program. (1984) (43)
Characterization of protein-polysaccharides of articular cartilage from mature and immature pigs. (1969) (43)
MRI demonstration of hypertrophic articular cartilage repair in osteoarthritis (2004) (42)
Therapeutic strategies distinguish community based primary care physicians from rheumatologists in the management of osteoarthritis. (1993) (42)
The effect of synovial hyaluronate on the ingestion of monosodium urate crystals by leukocytes. (1974) (42)
Organization of ground substance proteoglycans in normal and osteoarthritic knee cartilage. (1976) (42)
A pessimistic view of serologic markers for diagnosis and management of osteoarthritis. Biochemical, immunologic and clinicopathologic barriers. (1989) (41)
Synovial fluid concentrations of diclofenac in patients with rheumatoid arthritis or osteoarthritis. (1985) (41)
Risk factors for progression of tibiofemoral osteoarthritis: an analysis based on fluoroscopically standardised knee radiography (2005) (41)
NEUROPATHY, M COMPONENTS, AND AMYLOID (1975) (41)
Non-surgical treatment of osteoarthritis: a half century of “advances” (2004) (40)
Bone scintigraphy in the canine cruciate deficiency model of osteoarthritis. Comparison of the unstable and contralateral knee. (1997) (40)
Arthritis associated with inflammatory bowel disease in children (1986) (39)
Severity of joint pain and Kellgren-Lawrence grade at baseline are better predictors of joint space narrowing than bone scintigraphy in obese women with knee osteoarthritis. (2005) (39)
Procollagenase Is Reduced to Inactive Fragments upon Activation in the Presence of Doxycycline a (1994) (38)
Radiation synovectomy stimulates glycosaminoglycan synthesis by normal articular cartilage. (1989) (38)
Ageing in relation to the pathogenesis of osteoarthritis. (1986) (38)
Lack of association between serum keratan sulfate concentrations and cartilage changes of osteoarthritis after transection of the anterior cruciate ligament in the dog. (1989) (37)
Effects of salicylate and indomethacin on glycosaminoglycan and prostaglandin E2 synthesis in intact canine knee cartilage ex vivo. (1984) (37)
Relation of regional articular cartilage morphometry and meniscal position by MRI to joint space width in knee radiographs. (2009) (37)
Serial kinematic analysis of the canine hindlimb joints after deafferentation and anterior cruciate ligament transection. (1997) (37)
Neuromuscular aspects of osteoarthritis: a perspective. (2004) (37)
Association between concentrations of urinary type II collagen neoepitope (uTIINE) and joint space narrowing in patients with knee osteoarthritis. (2006) (36)
Should nonsteroidal anti-inflammatory drugs be used to treat osteoarthritis? (1993) (36)
Should the initial drug be used to treat osteoarthritis pain be a nonsteroidal antiinflammatory drug? (2001) (35)
Nonsteroidal Antiinflammatory Drugs in Treatment of Osteoarthritis (1986) (35)
Heterogeneity of protein-polysaccharides of porcine articular cartilage. The sequential extraction of chondroitin sulphate-proteins with iso-osmotic neutral sodium acetate. (1971) (35)
Practical management of osteoarthritis. Integration of pharmacologic and nonpharmacologic measures. (1995) (34)
Acute leukemia after azathioprine treatment of connective tissue disease. (1977) (34)
Hypothesis: can type IX collagen "glue" together intersecting type II fibers in articular cartilage matrix? A proposed mechanism. (1992) (34)
Alignment of the medial tibial plateau affects the rate of joint space narrowing in the osteoarthritic knee. (2010) (33)
Proteoglycan depletion, rather than fibrillation, determines the effects of salicylate and indomethacin on osteoarthritic cartilage. (1985) (32)
Effect of intraarticular hyaluronan injection on synovial fluid hyaluronan in the early stage of canine post-traumatic osteoarthritis. (2001) (32)
[Paracetamol in the treatment of osteoarthritis pain]. (2003) (32)
Comparison of quantitative and semiquantitative indicators of joint space narrowing in subjects with knee osteoarthritis (2005) (32)
Osteophytes in osteoarthritis. Clinical aspects. (1999) (32)
The concept of osteoarthritis as failure of the diarthrodial joint (2003) (32)
Bone scintigraphy is not a better predictor of progression of knee osteoarthritis than Kellgren and Lawrence grade. (2004) (31)
Should osteoarthritis be treated with nonsteroidal anti-inflammatory drugs? (1993) (31)
Prospective study of magnetic resonance imaging and SPECT bone scans in renal allograft recipients: evidence for a self-limited subclinical abnormality of the hip. (1993) (30)
Detecting and measuring disease modification in osteoarthritis. The need for standardized methodology. (1995) (30)
Work Group recommendations: 2002 Exercise and Physical Activity Conference, St Louis, Missouri. (2003) (30)
Varus malalignment negates the structure-modifying benefits of doxycycline in obese women with knee osteoarthritis. (2010) (29)
Educational support groups of patients with ankylosing spondylitis: a preliminary report. (1981) (29)
Accelerated clearance of albumin from the osteoarthritic knee: implications for interpretation of concentrations of "cartilage markers" in synovial fluid. (1996) (29)
Urinary levels of type II collagen C-telopeptide crosslink are unrelated to joint space narrowing in patients with knee osteoarthritis (2005) (28)
The therapeutic approaches of community based primary care practitioners to osteoarthritis of the hip in an elderly patient. (1991) (27)
Progressive increase in body mass index is not associated with a progressive increase in joint space narrowing in obese women with osteoarthritis of the knee (2008) (27)
Plain radiography as an outcome measure in clinical trials involving patients with knee osteoarthritis. (1999) (27)
Serial force plate analyses of dogs with unilateral knee instability, with or without interruption of the sensory input from the ipsilateral limb. (1999) (27)
Animal models of osteoarthritis. (2002) (27)
Type XI collagen is associated with the chondrocyte surface in suspension culture. (1989) (26)
Chalky joint effusion (1977) (26)
Correction of data on salicylate and indomethacin concentrations in cartilage. (1985) (25)
In vivo observations of hydraulic stiffening in the canine femoral head. (1997) (25)
Subject retention and adherence in a randomized placebo-controlled trial of a disease-modifying osteoarthritis drug. (2004) (25)
Simple analgesics versus NSAIDs for osteoarthritis (1993) (25)
Views of patients and physicians regarding the importance of various aspects of arthritis treatment. Correlations with health status and patient satisfaction (1986) (25)
Effects of oral doxycycline administration on histomorphometry and dynamics of subchondral bone in a canine model of osteoarthritis. (1996) (25)
Low dose prednisone treatment does not reduce the severity of osteoarthritis in dogs after anterior cruciate ligament transection. (1991) (25)
Impairment of osteophyte formation in hyperglycemic patients with type II diabetes mellitus and knee osteoarthritis. (1992) (25)
Pain, synovitis, and articular cartilage changes in osteoarthritis. (1989) (25)
Suppression of glycosaminoglycan synthesis by articular cartilage, but not of hyaluronic acid synthesis by synovium, after exposure to radiation. (1989) (24)
Failure of proteoglycans to form aggregates in morphologically normal aged human hip cartilage. (1977) (24)
Systemic Lupus Erythematosus: Association With Psoralen-Ultraviolet-A Treatment of Psoriasis (1979) (23)
Risk factors for early radiographic changes of tibiofemoral osteoarthritis (2006) (23)
The effect of intertrabecular fluid on femoral head mechanics. (1991) (23)
Correlation of serum concentrations of ibuprofen stereoisomers with clinical response in the treatment of hip and knee osteoarthritis. (1992) (22)
Benoxaprofen stimulates proteoglycan synthesis in normal canine knee cartilage in vitro. (1983) (22)
Predictors of mortality in non-post-operative patients with septic arthritis. (1992) (22)
Toward Pharmacologic Modification of Joint Damage in Osteoarthritis (1995) (22)
Development of radiographic changes of osteoarthritis in the “Chingford knee” reflects progression of disease or non-standardised positioning of the joint rather than incident disease (2003) (22)
Current practices for monitoring ocular toxicity related to hydroxychloroquine (Plaquenil) therapy. (1994) (22)
Serial kinematic analysis of the trunk and limb joints after anterior cruciate ligament transection: Temporal, spatial, and angular changes in a canine model of osteoarthritis. (1994) (21)
Experience with a placebo-controlled randomized clinical trial of a disease-modifying drug for osteoarthritis: the doxycycline trial. (2006) (21)
Reproducibility and sensitivity to change of a new method of computer measurement of joint space width in hip osteoarthritis. Performance of three radiographic views obtained at a 3-year interval. (2009) (21)
Neurogenic factors in the etiopathogenesis of osteoarthritis. (1993) (21)
Hyaluronic acid content of deep and subcutaneous bursae of man. (1983) (21)
Can a Nurse-Directed Intervention Reduce the Exposure of Patients With Knee Osteoarthritis to Nonsteroidal Antiinflammatory Drugs? (2004) (20)
Interaction of cartilage collagens with heparin. (1987) (20)
Systemic lupus erythematosus: association with psoralen--ultraviolet-A treatment of psoriasis. (1979) (20)
Cleavage of type XI collagen fibers by gelatinase and by extracts of osteoarthritic canine cartilage. (1991) (20)
Epigenetically mediated spontaneous reduction of NFAT1 expression causes imbalanced metabolic activities of articular chondrocytes in aged mice. (2016) (20)
Urinary TIINE concentrations in a randomized controlled trial of doxycycline in knee osteoarthritis: implications of the lack of association between TIINE levels and joint space narrowing. (2007) (19)
Heterogeneity of protein-polysaccharides of porcine articular cartilage. The chondroitin sulphate proteins associaterd with collagen. (1971) (19)
Type XI collagen-degrading activity in human osteoarthritic cartilage. (1990) (18)
Modification by oral doxycycline administration of articular cartilage breakdown in osteoarthritis. (1995) (18)
Is a Strong Quadriceps Muscle Bad for a Patient with Knee Osteoarthritis? (2003) (18)
Enhancement of urate solubility by connective tissue. I. Effect of proteoglycan aggregates and buffer cation. (1978) (18)
Metabolism of a cartilage matrix glycoprotein in normal and osteoarthritic canine articular cartilage. (1986) (17)
Effects of synovial fluid hyaluronan concentration and molecular size on clearance of protein from the canine knee. (1995) (17)
The relationship between meniscal tears and meniscal position (2010) (17)
Temporary immobilisation facilitates repair of chemically induced articular cartilage injury. (1984) (17)
A radiographic comparison of erosive osteoarthritis and idiopathic nodal osteoarthritis. (1992) (17)
Effects of diphosphonates on glycosaminoglycan synthesis and proteoglycan aggregation in normal adult articular cartilage. (1978) (17)
Serial kinematic analysis of the canine knee after L4-S1 dorsal root ganglionectomy: implications for the cruciate deficiency model of osteoarthritis. (1994) (16)
Allied health team management of rheumatoid arthritis patients. (1984) (16)
Effect of sodium salicylate, aspirin, and ibuprofen on enzymes required by the chondrocyte for synthesis of chondroitin sulfate. (1993) (16)
A critique of the 2000 update of the American College of Rheumatology recommendations for management of hip and knee osteoarthritis. (2001) (15)
Pathophysiology of osteoarthritis and effect of therapeutic interventions (1996) (15)
Cartilage matrix glycoprotein is present in serum in experimental canine osteoarthritis. (1989) (15)
Annals of Internal Medicine Quadriceps Weakness and Osteoarthritis of the Knee (1997) (15)
Topographic localization of a 116,000-dalton protein in cartilage. (1985) (15)
Iatrogenic morbidity accompanying suppression of temporal arteritis by adrenal corticosteroids. (1984) (14)
Characterization of normal and osteoarthritic cartilage using 25 MHz ultrasound (1990) (14)
Synovial fluid glycosaminoglycan concentration does not correlate with severity of chondropathy or predict progression of osteoarthritis in a canine cruciate deficiency model. (2000) (14)
Preliminary report: increased porosity of the subchondral plate in an accelerated canine model of osteoarthritis. (1997) (14)
In normal knees, joint space width (JSW) is correlated with the intermargin distance (IMD), a measure of medial tibial plateau alignment. Variations in IMD explain variability in JSW in serial radiographs. (2013) (14)
Cardiovascular abnormalities in the Marfanoid hypermobility syndrome. (1976) (13)
The presence of cartilage matrix glycoprotein in serum as determined by immunolocation analysis is not a sensitive indicator of "early" osteoarthritis of the knee. (1991) (13)
Animal models: insights into osteoarthritis (OA) provided by the cruciate-deficient dog. (1991) (13)
Hyaluronan injection affects neither osteoarthritis progression nor loading of the OA knee in dogs. (2004) (13)
Effects of Voltaren on arachidonic acid metabolism in arthritis patients. (1985) (13)
Nonsurgical management of osteoarthritis, with an emphasis on nonpharmacologic measures. (1995) (12)
Malalignment and subchondral bone turnover in contralateral knees of overweight/obese women with unilateral osteoarthritis: Implications for bilateral disease (2011) (12)
Osteoarthritis: definitions and criteria. (1990) (12)
Chalky joint effusion. The result of massive synovial deposition of calcium apatite in progressive systemic sclerosis. (1977) (12)
Osteoarthritis and crystal deposition diseases. (1996) (12)
Characterization of the mucopolysaccharides associated with fractions of guanidine-denatured amyloid fibrils. (1974) (12)
Structure-function relationships in indium-111 radioimmunoconjugates. (1992) (12)
Osteoarthritis, 2nd edition (2003) (12)
Effect of calcipenia on proteoglycan metabolism and aggregation in normal articular cartilage in vitro. (1979) (11)
Small proteoglycans of cartilage: confirmation of their presence by non-disruptive extraction. (1974) (11)
Partial reversal by beta-D-xyloside of salicylate-induced inhibition of glycosaminoglycan synthesis in articular cartilage. (1982) (11)
Effect of polyanions on fibrillogenesis by type XI collagen. (1987) (11)
Diagnosis And Nonsurgical Management of Osteoarthritis (2000) (11)
Team care for patients with chronic rheumatic disease. (1982) (11)
Immunological relationships between proteoglycans of different hydrodynamic size from articular cartilage of foetal and mature pigs. (1973) (10)
Inhibition of recombinant human neutrophil collagenase by doxycycline is pH dependent. (1997) (10)
Joint effusions after kidney transplantation. (1979) (10)
Stimulation of glycosaminoglycan biosynthesis by amyloid fibrils. (1975) (10)
Effect of naproxen sodium on the net synthesis of glycosaminoglycans and protein by normal canine articular cartilage in‐vitro (1990) (10)
Pneumococcal pyomyositis: a patient with diagnostic problems and complications. (2001) (10)
Destruction of joint homografts (1977) (10)
Erosive temporomandibular joint disease as a feature of the spondyloarthropathy of ulcerative colitis. (1982) (10)
Effects of salicylate on chondrocytes from osteoarthritic and contralateral knees of dogs with unilateral anterior cruciate ligament transection. (1989) (10)
Studies in animal models of osteoarthritis as predictors of a structure-modifying effect of diacerhein in humans with osteoarthritis. (2006) (9)
Effects of Tiaprofenic Acid on the Concentration and Metabolism of Proteoglycans in Normal and Degenerating Canine Articular Cartilage (1990) (9)
Dibutyryl cyclic AMP affects hyaluronate synthesis and macromolecular organization in normal adult articular cartilage in vitro. (1980) (8)
Osteoarthritis and crystal deposition diseases. (1992) (8)
Sex differences in medical student and housestaff attitudes toward the handicapped. (1986) (8)
Benoxaprofen reduces osteophyte formation and fibrillation after articular cartilage injury. (1985) (8)
Differences in composition and size of protein‐polysaccharides extracted from pig articular cartilage (1969) (8)
[Effects of diacerhein on canine model with accelerated osteoarthritis]. (1997) (8)
A 2-year randomized, double-blind, placebo-controlled, multicenter study of an oral selective iNOS inhibitor in subjects with symptomatic osteoarthritis of the knee (2012) (8)
Clinical rheumatology training in an uncertain future. Opinions of recent and current rheumatology fellows about an extended fellowship in musculoskeletal medicine. (1994) (8)
Fibrous replacement of the deltoid muscle: a remediable cause of abduction contracture of the shoulder in scleroderma. (1977) (7)
Identification of a high-molecular-weight (greater than 400 000) protein in hyaline cartilage. (1984) (7)
The futility of current approaches to chondroprotection - a different perspective: comment on the article by Felson and Kim. (2007) (7)
Characterization of antibody-chelator conjugates: determination of chelator content by terbium fluorescence titration. (1991) (7)
An Atlas of Osteoarthritis (2001) (7)
Compensation and decompensation of articular cartilage in osteoarthritis (1993) (6)
The Antigenicity of Extracellular Proteoglycans: Implications for Structure and Biosynthesis (1973) (6)
AspIrin causes in vivo synthesis of type i collagen by atrophic articular cartilage. (1983) (6)
Multipurpose arthritis centers (1988) (6)
Chondrocalcinosis, osteophytes and osteoarthritis (2003) (6)
The physiology of articular stress: osteoarthrosis. (1987) (6)
Hereditary symphalangism. Association with osteoarthritis. (1989) (6)
Some effects on house officers of an elective rheumatology rotation. (1980) (6)
Osteoarthritis and crystal deposition diseases. (1993) (6)
Translating osteoarthritis into numbers: the importance of alignment in knee radiography for clinical trials of structure-modifying drugs. (2005) (6)
Nonsteroidal antiinflammatory drugs and articular cartilage. (1987) (5)
Misoprostol Does Not Protect Articular Cartilage From Salicylate‐Induced Suppression of Proteoglycan Synthesis (1991) (5)
Rapid, simple detection of trace amounts of synovial fluid. (1973) (5)
Effect of a rheumatology elective on house officers' evaluation of rheumatoid arthritis. (1980) (5)
How financial barriers can frustrate good arthritis care. (1988) (5)
Improved training of house officers in a rheumatology consult service. (1993) (5)
Amyloidosis of the stomach associated with impaired gastric secretion of intrinsic factor and the development of vitamin B12 deficiency. (1968) (5)
Relationships between clinical features and distribution of mononuclear cells in muscle of patients with polymyositis. (1988) (5)
Various health professions groups' beliefs about people with arthritis. (1986) (5)
Guidelines for testing slow acting drugs in arthritis--addendum. (1995) (5)
Osteoarthritis and crystal deposition diseases. (1998) (5)
Popliteal cyst mimicking thrombophlebitis as the first indication of knee disease. (1979) (5)
Why should we expect a structure-modifying osteoarthritis drug to relieve osteoarthritis pain? (2011) (5)
Degradative enzymes of cartilage. Effects of freeze-thawing of the tissue prior to extraction, and of protease inhibitors, on proteoglycans extracted with iso-osmotic neutral salt and 4 M guanidinium chloride. (1977) (5)
Arterial mesenchyme and arteriosclerosis. Some aspects of the organization and interaction of connective tissue proteoglycans. (1974) (5)
Defining Osteoarthritis: What It Is, and What It Is Not (2010) (5)
Medical therapy of osteoarthritis of the knee [2] (1991) (4)
VI Connective and Cartilaginous Tissue Effects of Altered Load on Canine Articular Cartilage In Vivo and In Vitro (1984) (4)
Disease-modifying osteoarthritis drugs (2001) (4)
Arthritis care in older-adult centers (1987) (4)
Osteoarthritis Diagnosis: Avoiding the Pitfalls (2010) (4)
Studies of synovial hyaluronic acid synthesis in canine osteoarthritis. (1987) (4)
Synthesis of a phenotypically abnormal type XI: type II collagen ratio by chondrocytes from canine osteoarthritic cartilage. (1994) (4)
A LONGITUDINAL STUDY OF SUBCHONDRAL PLATE AND TRABECULAR BONE IN FOLLOWED UP FOR 54 MONTHS CRUCIATE-DEFICIENT DOGS WITH OSTEOARTHRITIS (1993) (3)
Update of proceedings of the 2002 International Workshop on Osteoarthritis Outcomes (2005) (3)
Arthritis care in older-adult centers. A controlled study of an education program for public health nurses. (1987) (3)
Serial kinematic analysis of canine hind limb joints after unilateral L4-S1 dorsal root ganglionectomy: Insights into locomotor control mechanisms. (1995) (3)
Adjudication process for joint events of interest in fulranumab clinical trial program (2013) (3)
Management of osteoarthritis - the comprehensive approach (2003) (3)
Second-line drug therapy for osteoarthritis. (2001) (3)
Prevalence and Correlates of the Type a Behavior Pattern in Patients with Rheumatoid Arthritis (1985) (3)
Effects of nonsteroidal antiinflammatory drugs on proteoglycan metabolism in articular cartilage (1981) (3)
Infectious complications complications of cyclophosphamide treatment for vasculitis (1989) (2)
Enhancement of urate solubility by connective tissue. II. Inhibition of sodium urate crystallisation by cation exchange. (1979) (2)
NSAIDs in the treatment of osteoarthritis. Friends or foes? (1993) (2)
2 OARSI TREATMENT GUIDELINES FOR HIP AND KNEE OSTEOARTHRITIS (2006) (2)
Diagnosis-related group regulations. Implications for the practicing rheumatologist. (1985) (2)
Methodology and statistical analysis in the Glucosamine/Chondroitin Arthritis Intervention Trial: comment on the article by Sawitzke et al. (2009) (2)
A behaviorally effective model for training of general health professionals by a rheumatology team. (1991) (2)
The randomized clinical trial of doxycycline in knee osteoarthritis: comment on the editorial by Dieppe. (2006) (2)
Issues in Pharmacological Management of Osteoarthritis (2011) (2)
Osteoarthritis and crystal deposition diseases: Editorial overview (1990) (2)
Acute joint dislocation--an early feature of neuropathic arthropathy. (1976) (2)
Proteoglycan aggregation in injured articular cartilage. A comparison of healing lacerated cartilage with osteoarthritic cartilage. (1982) (2)
Destruction of joint homografts. An experimental study. (1977) (2)
Multipurpose arthritis centers. A ten-year progress report. (1988) (2)
Effect of joint disuse and subsequent exercise on proteoglycan metabolism and aggregation in articular cartilage (1981) (2)
Periosteal new bone formation in a canine neuropathic model of osteoarthritis. (1997) (2)
Simple analgesics versus NSAID. (2002) (1)
3.2 Animal Models of Osteoarthritis (1999) (1)
Key questions concerning paracetamol and NSAIDs for OA (2003) (1)
The effects of salicylates and other non-steroidal antiinframmatory drugs on articular cartilage (1984) (1)
Crystal deposition diseases and osteoarthritis Editorial overview (1989) (1)
OSTEOARTHRITIS and CARTILAGE Serial kinematic analysis of the canine hindlimb joints after deafferentation and anterior cruciate ligament t ransection (1997) (1)
Epidemiology of Osteoarthritis: International Workshop (1994) (1)
Reduced NFAT1 expression is a risk factor for dysfunction of articular chondrocytes and development of osteoarthritis in aged mice (2014) (1)
Diagnosis of osteoarthritis (1993) (1)
Osteoarthritis clinical trials have not identified efficacious therapies because traditional imaging outcome measures are inadequate (2013) (1)
Pharmacological modification of joint breakdown in OA: Do we need it, can we do it, can we prove it, is it good? (2003) (1)
Osteoarthritis and crystal deposition diseases. (1994) (0)
Use of esting Splints by Patients with heum.atoid Arthritis (2015) (0)
Cartilage metabolism--a response. (1995) (0)
Matters Arising Key Questions concerning Paracetamol and Nsaids for Oa Authors' Reply Reduction of Jaw Opening in Giant Cell Arteritis (0)
Educational Needs of Vocational Rehabilitation Counselors Working With Clients Who Have Arthritis (1984) (0)
Measurements of urinary coll2-1no2 is predictif of joint space narrowing in knee osteoarthritis (2012) (0)
Hyaluronic acid contentofdeepandsubcutaneous bursae ofman (1983) (0)
396 RELATION OF REGIONAL ARTICULAR CARTILAGE MORPHOMETRY AND MENISCAL POSITION BY MRI TO JSW IN KNEE RADIOGRAPHS (2008) (0)
262 DOES INCREASING OBESITY INCREASE THE PROGRESSION OF KNEE OSTEOARTHRITIS (2007) (0)
[Anti-inflammatory and analgesic treatment of osteoarthritis]. (1996) (0)
NFAT1 deficiency causes cellular dysfunction and ectopic ossification in murine intervertebral joints (2017) (0)
Special report: supporting patient self-care for osteoarthritis (2001) (0)
Medical management of the patient with arthritis. (1974) (0)
[Joint radiography in patients with gonarthrosis]. (2000) (0)
Allied Health TeaDl ManageDlent of RheuDlatoid Arthritis Patients (health care delivery, occupational therapy practice, patient care team) (2015) (0)
Osteoarthritis. Preface. (2003) (0)
Proceedings of the Second Update on Psoriatic Disease, University Federico II Congress Center, July 6–7, 2011, Naples, Italy. (2012) (0)
Resources for treatment of arthritis in Indiana. (1985) (0)
342 REPRODUCIBILITY AND LONGITUDINAL CHANGE IN THE ANATOMIC-AXIS ANGLE IN KNEE RADIOGRAPHS: IMPLICATIONS FOR RELATING PROGRESSIVE MALALIGNMENT TO JOINT SPACE NARROWING IN KNEE OSTEOARTHRITIS (2007) (0)
Osteoarthritis and crystal deposition diseases. (1996) (0)
117 TIINE MEASUREMENT OF TYPE II COLLAGEN BREAKDOWN AND JOINT SPACE NARROWING (JSN) IN THE RANDOMIZED CLINICAL TRIAL (RCT) OF DOXYCYCLINE (DOXY) IN OSTEOARTHRITIS (OA) (2007) (0)
Deficiency of nfat1 transcription factor causes osteoarthritis with alterations in articular cartilage and subchondral bone in adult mice (2012) (0)
THE CHONDROITIN SULPHIATE PROTEINS ASSOCIATED WITH COLLAGEN (2005) (0)
century of "advances" Non-surgical treatment of osteoarthritis: a half (2006) (0)
Risk Factors for Progression of Tibiofemoral Osteoarthritis : An Analysis Based on Fluoroscopically Standardized Knee Radiography ( Extended Report ) (2005) (0)

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Indiana University