Kenneth Ira Berns
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Why Is Kenneth Ira Berns Influential?
(Suggest an Edit or Addition)Kenneth Ira Berns's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Site-specific integration by adeno-associated virus. (1990) (877)
- Gene Therapy Using Adeno-Associated Virus Vectors (2008) (793)
- Nucleotide sequence and organization of the adeno-associated virus 2 genome (1983) (696)
- Characterization of a preferred site on human chromosome 19q for integration of adeno‐associated virus DNA by non‐homologous recombination. (1992) (508)
- Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells. (1982) (422)
- Mapping and direct visualization of a region-specific viral DNA integration site on chromosome 19q13-qter. (1991) (344)
- ISOLATION OF HIGH MOLECULAR WEIGHT DNA FROM HEMOPHILUS INFLUENZAE. (1965) (322)
- Characteristics and taxonomy of Parvoviridae. (1985) (313)
- Biology of adeno-associated virus. (1996) (305)
- The cryptic life style of adenoassociated virus (1995) (301)
- Integration of the adeno-associated virus genome into cellular DNA in latently infected human Detroit 6 cells (1980) (298)
- Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutants (1984) (294)
- Rescue of adeno-associated virus from recombinant plasmids: Gene correction within the terminal repeats of AAV (1983) (293)
- Site-specific integration by adeno-associated virus. (1990) (244)
- The recombination signals for adeno-associated virus site-specific integration. (1996) (241)
- AAV-mediated gene transfer of pigment epithelium-derived factor inhibits choroidal neovascularization. (2002) (234)
- Parvovirus replication. (1990) (224)
- Nucleotide sequence of the inverted terminal repetition in adeno-associated virus DNA (1980) (216)
- Adeno-associated viruses: an update. (1987) (200)
- Positive and negative autoregulation of the adeno-associated virus type 2 genome (1986) (200)
- Characterization and localization of the naturally occurring cross-links in vaccinia virus DNA. (1974) (194)
- Phase I trial of intramuscular injection of a recombinant adeno-associated virus serotype 2 alphal-antitrypsin (AAT) vector in AAT-deficient adults. (2006) (180)
- Evidence for a single-stranded adenovirus-associated virus genome: formation of a DNA density hybrid on release of viral DNA. (1969) (178)
- Expression from the adeno-associated virus p5 and p19 promoters is negatively regulated in trans by the rep protein (1989) (177)
- Site-specific integration by adeno-associated virus is directed by a cellular DNA sequence. (1994) (156)
- Detection of adeno-associated virus (AAV)-specific nucleotide sequences in DNA isolated from latently infected Detroit 6 cells. (1975) (153)
- Adeno-associated virus gene expression inhibits cellular transformation by heterologous genes (1987) (147)
- Origin and termination of adeno-associated virus DNA replication. (1977) (144)
- Organization of adeno-associated virus DNA in latently infected Detroit 6 cells. (1989) (136)
- Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1–3 of angiostatin reduce retinal neovascularization (2002) (123)
- Effect Of DNA-dependent protein kinase on the molecular fate of the rAAV2 genome in skeletal muscle (2001) (119)
- Evidence for a Single-Stranded Adenovirus-Associated Virus Genome: Isolation and Separation of Complementary Single Strands (1970) (116)
- Separation of Two Types of Adeno-Associated Virus Particles Containing Complementary Polynucleotide Chains (1972) (106)
- DNA-dependent PK inhibits adeno-associated virus DNA integration (2004) (104)
- Interleukin 10 attenuates neointimal proliferation and inflammation in aortic allografts by a heme oxygenase-dependent pathway. (2005) (103)
- A p5 integration efficiency element mediates Rep-dependent integration into AAVS1 at chromosome 19 (2002) (100)
- Inhibition of adenovirus-transformed cell oncogenicity by adeno-associated virus. (1981) (95)
- Mapping of the 5' termini of two adeno-associated virus 2 RNAs in the left half of the genome (1982) (92)
- Recombinant junctions formed by site-specific integration of adeno-associated virus into an episome (1995) (92)
- Adaptations of Avian Flu Virus Are a Cause for Concern (2012) (91)
- Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors. (2005) (91)
- Sequence and symmetry requirements within the internal palindromic sequences of the adeno-associated virus terminal repeat. (1988) (87)
- Adeno-associated viruses. (1979) (86)
- A study of single polynucleotide chains derived from T2 and T4 bacteriophage (1961) (83)
- The physical characterization of DNA molecules released from T2 and T4 bacteriophage. (1961) (75)
- Role of the Adenovirus DNA-Binding Protein in In Vitro Adeno-Associated Virus DNA Replication (1998) (71)
- AAV: An Overview of Unanswered Questions. (2017) (71)
- Adeno-Associated Virus Type 2 and Hepatocellular Carcinoma? (2015) (70)
- Arrangement of nucleotide sequences in adeno-associated virus DNA. (1973) (68)
- Proceedings of the Third International Symposium on Retinopathy of Prematurity: an update on ROP from the lab to the nursery (November 2003, Anaheim, California). (2006) (67)
- Adenovirus and Adeno‐Associated Virus as Vectors for Gene Therapy a (1995) (64)
- Adeno-associated virus DNA replication: nonunit-length molecules. (1979) (63)
- Conformation takes precedence over sequence in adeno-associated virus DNA replication (1984) (62)
- Gene delivery in renal tubular epithelial cells using recombinant adeno-associated viral vectors. (2003) (61)
- Efficient Integration of Recombinant Adeno-Associated Virus DNA Vectors Requires a p5-rep Sequence in cis (2002) (61)
- Adeno-associated virus: a ubiquitous commensal of mammals. (2005) (59)
- Letter: Visualization of the inverted terminal repetition in adeno-associated virus DNA. (1974) (58)
- Regulated high-level human beta-globin gene expression in erythroid cells following recombinant adeno-associated virus-mediated gene transfer. (1995) (58)
- Adeno-Associated Virus Site-Specific Integration and AAVS1 Disruption (2004) (57)
- Natural Occurrence of Cross-Linked Vaccinia Virus Deoxyribonucleic Acid (1970) (57)
- Adeno-associated virus DNA replication in vitro: activation by a maltose binding protein/Rep 68 fusion protein (1994) (53)
- Parvovirus gene regulation. (1987) (51)
- The adeno-associated virus rep gene inhibits replication of an adeno-associated virus/simian virus 40 hybrid genome in cos-7 cells (1988) (50)
- Adeno-Associated Virus (AAV) Vectors in Gene Therapy (1996) (50)
- Adeno-Associated Virus Site-Specific Integration Is Mediated by Proteins of the Nonhomologous End-Joining Pathway (2009) (49)
- Structure and nucleotide sequence of the terminal regions of adeno-associated virus DNA. (1977) (48)
- In vitro rescue of an integrated hybrid adeno-associated virus/simian virus 40 genome. (1991) (47)
- Policy: Adaptations of avian flu virus are a cause for concern (2012) (44)
- The remaining stocks of smallpox virus should be destroyed. (1993) (42)
- Regulation of adeno-associated virus DNA replication. (1988) (41)
- DNA Sequence Motifs Which Direct Adeno-Associated Virus Site-Specific Integration in a Model System (2000) (41)
- Inverted terminal repetition in adeno-associated virus DNA: independence of the orientation at either end of the genome (1981) (40)
- The Reoviridae (1983) (39)
- Adenovirus early region 1b gene function required for rescue of latent adeno-associated virus. (1980) (38)
- Adeno-associated virus (AAV) site-specific integration: formation of AAV-AAVS1 junctions in an in vitro system. (1999) (37)
- In vitro replication of adeno-associated virus DNA. (1992) (37)
- Adeno-Associated Virus DNA Structure and Replication (1984) (35)
- In vitro replication of adeno-associated virus DNA: enhancement by extracts from adenovirus-infected HeLa cells (1996) (35)
- Recombinant angiostatin prevents retinal neovascularization in a murine proliferative retinopathy model (2001) (34)
- Adeno-associated virus DNA replication. (1979) (34)
- Molecular biology of adeno-associated viruses. (2000) (34)
- Evidence for two nucleotide sequence orientations within the terminal repetition of adeno-associated virus DNA (1977) (34)
- The Brighton Collaboration Viral Vector Vaccines Safety Working Group (V3SWG). (2015) (33)
- Study of the fine structure of adeno-associated virus DNA with bacterial restriction endonucleases (1975) (33)
- Characterization of the Mouse Adeno-Associated Virus AAVS1 Ortholog (2004) (33)
- Intermediates of adeno-associated virus DNA replication in vitro (1994) (32)
- The genetics of adeno-associated virus. (1984) (32)
- Minimum origin requirements for linear duplex AAV DNA replication in vitro. (1995) (29)
- Characterization of a bipartite recombinant adeno-associated viral vector for site-specific integration. (2007) (27)
- Adeno-associated virus type 2: a latent life cycle. (1994) (27)
- Site-specific integration by adeno-associated virus: a basis for a potential gene therapy vector (1997) (26)
- Range of retinal diseases potentially treatable by AAV-vectored gene therapy. (2004) (25)
- Molecular biology of the adeno-associated viruses. (1974) (24)
- Recombination between simian virus 40 and adeno-associated virus: virion coinfection compared to DNA cotransfection. (1984) (21)
- The utility of formaldehyde in stabilizing polynucleotide chains from bacteriophage DNA. (1962) (21)
- The Unusual Properties of the AAV Inverted Terminal Repeat. (2020) (21)
- AAV's Golden Jubilee. (2015) (20)
- Site-Specific Integration of Adeno-Associated Virus into an Episome with the Target Locus via a Deletion-Substitution Mechanism (1998) (19)
- Polyoma-like particle: characterization of the DNA encapsidated in vitro by polyoma empty capsids. (1982) (19)
- Structure of simian virus 40-adeno-associated virus recombinant genomes (1985) (19)
- Interactions between the termini of adeno-associated virus DNA. (1989) (18)
- Parvovirus replication (1990) (18)
- Genome localization of adeno-associated virus RNA (1976) (17)
- Simplified production of a recombinant human angiostatin derivative that suppresses intracerebral glial tumor growth. (1999) (15)
- The Multinational Coordinated Arabidopsis Thaliana Genome Research Project (1996) (14)
- Adeno-associated virus-mediated expression of vascular endothelial growth factor peptides inhibits retinal neovascularization in a mouse model of oxygen-induced retinopathy. (2005) (14)
- Cloning, expression, and partial purification of Rep78: an adeno-associated virus replication protein. (1994) (14)
- Preventing academic medical center from becoming an oxymoron (1996) (13)
- Preventing the misuse of microorganisms: the role of the American Society for Microbiology in protecting against biological weapons. (1998) (13)
- CLONING OF AAV INTO pBR322: RESCUE OF INTACT VIRUS FROM THE RECOMBINANT PLASMID IN HUMAN CELLS (1982) (13)
- Next Generation of Adeno-Associated Virus Vectors for Gene Therapy for Human Liver Diseases. (2019) (12)
- Resource Sharing in Biomedical Research (1996) (11)
- Separation of a New Deoxyribonucleic Acid Polymerase from Vaccinia-infected HeLa Cells (1969) (9)
- Locus control region elements HS2 and HS3 in combination with chromatin boundaries confer high‐level expression of a human β‐globin transgene in a centromeric region (2004) (8)
- Grand Challenges for Biosafety and Biosecurity (2014) (8)
- Good news on the clinical gene transfer front. (2008) (8)
- Unique events in parvovirus replication. (1984) (8)
- Adeno-Associated Virus GeneExpression Inhibits Cellular Transformation byHeterologous Genes (1987) (7)
- Recovery of herpes simplex type 1 from the celiac ganglion after renal transplantation. (1984) (6)
- Gene Therapy: Use of Viruses as Vectors (2008) (6)
- Recombinant adeno-associated virus-mediated expression of O6-alkylguanine-DNA-alkyltransferase protects human epithelial and hematopoietic cells against chloroethylating agent toxicity. (1999) (5)
- Adeno-Associated Virus (1984) (5)
- Adeno-Associated VirusDNA Replication InVitro: Activation bya Maltose Binding Protein/Rep 68Fusion Protein (1994) (5)
- My life with adeno-associated virus: a long time spent studying a short genome. (2013) (5)
- Adeno‐associated viral vectors for gene therapy (2005) (4)
- Capturing the promise of science in medical schools (1996) (3)
- The Gordon Wilson Lecture. From basic virology to human gene therapy. (1999) (3)
- ADENO-ASSOCIATED VIRUS DNA REPLICATION (1980) (3)
- The Language of Life by Francis S. Collins (2010) HarperCollins, New York. (2010) (2)
- REVIEW ARTICLE Parvovirus Gene Regulation (1987) (2)
- The physical characterization of DNA molecules from T2 and T4 bacteriophage (1961) (2)
- The Washington Regional Primate Research Center (1996) (2)
- Committee on Resource Sharing in Biomedical Research (1996) (1)
- Use of recombinant angiostatin to prevent retinal neovascularization. (2001) (1)
- Adeno‐associated virus mediated gene therapy for vascular retinopathies (2005) (1)
- Virus Vectors Gene Therapy Using Adeno-Associated (2014) (1)
- Viral Vectors for Gene Therapy (2010) (1)
- AAV-mediated Expression of Angiostatin Increases Intraocular Levels of PEDF (2003) (0)
- AAV-mediated Expression of PEDF or Angiostatin (K1K3) Reduces Retinal Neovascularization in a Mouse Model of Ischemic Retinopathy (2002) (0)
- Cloning of the Adeno-Associated Virus Genome (1984) (0)
- The Human Genome Center: Lawrence Livermore National Laboratory (1996) (0)
- Next Generation of AAV Vectors for Gene Therapy of Human Liver Diseases (2019) (0)
- The Jackson Laboratory (1996) (0)
- ASM and Biological Arms Control (1995) (0)
- The Path of Biomedical Research (2000) (0)
- WORKSHOP SUMMARY: REPLICATING LINEAR DNA MOLECULES (1980) (0)
- Gene Therapy for Neovascular Retinopathies (2006) (0)
- The Macromolecular Crystallography Resource at the Cornell High-Energy Synchrotron Source (1996) (0)
- AAV–mediated expression of VEGF peptides inhibits retinal neovascularization (NV) in a Mouse Model of Retinopathy of Prematurity (ROP) (2004) (0)
- DNS integration site of the human Adenassoziierten virus and its use (1993) (0)
- Inhibition of Retinal Neovascularization (NV) by AAV-mediated Gene Transfer of Endostatin in a Mouse Model of Retinopathy of Prematurity (ROP) (2003) (0)
- StudyoftheFineStructure ofAdeno-Associated VirusDNA withBacterial Restriction Endonucleases (1975) (0)
- Expression fromtheAdeno-Associated Virus p5 andp19Promoters IsNegatively Regulated intransbytherepProtein (1989) (0)
- The American Type Culture Collection (1934) (0)
- Site-specific integration by adeno-associated virus ( parvovirus / gene therapy / targeted integration / DNA replication / recombination ) (2005) (0)
- Latency by Herpes simplex Viruses (1991) (0)
- adeno-associated virus type 2 genome. Positive and negative autoregulation of the (2013) (0)
- " Verdohemochrome IXa : Preparation and oxidoreductive cleavage to biliverdin IXa (2003) (0)
- The Adenoviruses (1984) (0)
- Adeno-Associated Viruses (AAV) (2007) (0)
- Workshop on Resource Sharing in Biomedical Research (1996) (0)
- Mechanism of Adeno-Associated Virus Latent Infection (1984) (0)
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