Kevin J. Lafferty
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Kevin J. Laffertybiology Degrees
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Biology
Kevin J. Lafferty's Degrees
- PhD Ecology University of California, Santa Barbara
- Masters Biology University of California, Santa Barbara
- Bachelors Biology University of California, Santa Barbara
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(Suggest an Edit or Addition)Kevin J. Lafferty's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A new analysis of allogeneic interactions. (1975) (584)
- Immunobiology of tissue transplantation: a return to the passenger leukocyte concept. (1983) (526)
- Pancreatic islet-specific T-cell clones from nonobese diabetic mice. (1989) (264)
- Thyroid allograft immunogenicity is reduced after a period in organ culture. (1975) (230)
- The Origin and Mechanism of the Allograft Reaction (1977) (222)
- The Th1/Th2 balance in autoimmunity. (1995) (217)
- T-Lymphocyte Clone Specific for Pancreatic Islet Antigen (1988) (215)
- Altered cytokine activity in adjuvant inhibition of autoimmune diabetes. (1993) (176)
- Activation of transplant immunity: effect of donor leukocytes on thyroid allograft rejection. (1976) (169)
- The role of CD4+ and CD8+ T cells in the destruction of islet grafts by spontaneously diabetic mice. (1991) (163)
- EFFECT OF ORGAN CULTURE ON THE SURVIVAL OF THYROID ALLOGRAFTS IN MICE (1976) (161)
- Role of Lymphokine and Antigen in the Control of Specific T Cell Responses (1980) (147)
- Successful Allotransplantation of Mouse Pancreatic Islets to Nonimmunosuppressed Recipients (1980) (141)
- Autoimmune Diabetes in NOD Mouse Is L3T4 T-Lymphocyte Dependent (1987) (139)
- Inhibition of T‐Cell Activity by Cyclosporin A (1982) (131)
- Combined Treatment With Nicotinamide and Desferrioxamine Prevents Islet Allograft Destruction in NOD Mice (1986) (124)
- Evidence of recurrent autoimmunity in human allogeneic islet transplantation. (1996) (121)
- CELLULAR CHANGES IN CULTURED MOUSE THYROID GLANDS AND ISLETS OF LANGERHANS (1980) (116)
- Allogeneic stimulation modulates the in vitro response of T cells to transplantation antigen (1974) (114)
- The interaction between virus and antibody: III. Examination of virus-antibody complexes with the electron microscope (1963) (99)
- Reactions of the graft versus host (GVH) type. (1969) (97)
- The enchancement of virus infectivity by antibody. (1967) (88)
- THE INTERACTION BETWEEN VIRUS AND ANTIBODY. II. MECHANISM OF THE REACTION. (1963) (86)
- THE INTERACTION BETWEEN VIRUS AND ANTIBODY. I. KINETIC STUDIES. (1963) (85)
- CD8 T Cells Are Not Required for Islet Destruction Induced by a CD4+ Islet-Specific T-Cell Clone (1992) (79)
- Activation of cytotoxic T cells by nonstimulating tumor cells and spleen cell factor(s). (1977) (71)
- Islet Allografts Are Destroyed by Disease Occurrence in the Spontaneously Diabetic BB Rat (1986) (71)
- Immunological induction of T lymphocytes: role of antigen and the lymphocyte costimulator. (1978) (65)
- Diabetes results from a late change in the autoimmune response of NOD mice. (1997) (65)
- Prevention of Detrimental Effect of Cyclosporin A on Vascular Ingrowth of Transplanted Pancreatic Islets With Verapamil (1989) (64)
- An improved assay method for neutralizing antibodies against influenza viruses (1958) (61)
- Modulation of tissue immunogenicity by organ culture. Comparison of adult islets and fetal pancreas. (1980) (58)
- The role of the lymphatic system and lymphoid cells in the establishment of immunological memory. (1970) (56)
- Desferrioxamine Treatment Prevents Chronic Islet Allograft Damage (1986) (56)
- A Simple, Conservative Explanation of the H‐2 Restriction of Interactions Between Lymphocytes (1977) (53)
- Role of the L3T4+ T cell in allograft rejection. (1987) (53)
- RS-61443 allows islet allografting and specific tolerance induction in adult mice. (1990) (49)
- An improved assay for interleukin 2 (lymphocyte growth factor) produced by mitogen-activated lymphocytes. (1980) (47)
- Reversal of diabetes by allogenic islet transplantation without immunosuppression. (1980) (45)
- Pancreatic Islet Allograft Immunity and Tolerance: the Two‐Signal Hypothesis Revisited (1996) (43)
- Reversal diabetes by islet transplantation: vulnerability of the established allograft. (1981) (43)
- H‐2 COMPLEX AND Ia ANTIGENS ON CELLS DISSOCIATED FROM MOUSE THYROID GLANDS AND ISLETS OF LANGERHANS (1980) (43)
- The maintenance of self‐tolerance (1993) (42)
- FACILITATION OF SPECIFIC TOLERANCE INDUCTION IN ADULT MICE BY RS‐61443 (1992) (42)
- Protection from autoimmune diabetes by adjuvant therapy non‐obese diabetic mouse: The role of interleukin‐4 and interleukin‐10 (1997) (41)
- Induction and management of diabetes mellitus in the pig. (1986) (40)
- ANTIBODY AS INHIBITOR OF RIBONUCLEASE: THE ROLE OF STERIC HINDRANCE, AGGREGATE FORMATION, AND SPECIFICITY (1963) (38)
- Mechanism of thyroid allograft rejection. (1976) (37)
- EFFECT OF CYCLOSPORINE ON IMMUNOLOGICALLY MEDIATED DIABETES IN NONOBESE DIABETIC MICE1 (1988) (37)
- Role of lymphokine in islet allograft rejection. (1990) (37)
- An improved system for the assay of stimulation in mouse mixed leucocyte cultures. (1974) (35)
- CULTURED THYROID ALLOGRAFTS INDUCE A STATE OF PARTIAL TOLERANCE IN ADULT RECIPIENT MICE (1983) (35)
- Interleukin 2 Production by Both Ly2+ and Ly2− T‐Cell Subsets (1981) (34)
- Cytotoxic and proliferative lymphocyte responses to allogeneic and xenogeneic antigens in vitro. (1979) (33)
- Mycophenolate Mofetil Can Prevent the Development of Diabetes in BB Rats a (1993) (33)
- Autoimmune diabetes: the involvement of benign and malignant autoimmunity. (1999) (32)
- Establishment of islet-specific T-cell lines and clones from islet isografts placed in spontaneously diabetic NOD mice. (1993) (32)
- Allogeneic Interactions Provide Evidence for a Novel Class of Immunological Reactivity (1972) (31)
- Characterization of primary T cell subsets mediating rejection of pancreatic islet grafts. (1989) (31)
- A comparative study of transplant sites for endocrine tissue transplantation in the pig. (1986) (29)
- Attachment of Antibody to Influenza Virus (1961) (28)
- Studies on the two-signal model for T cell activation in vivo. (1987) (27)
- Prevention of rejection by treatment of the graft: an overview. (1986) (26)
- The Reversal of Diabetes by Pancreatic Islet Transplantation (1982) (26)
- The discriminatory capacity of phagocytic cells in chiton (Liolophura gaimardi). (1975) (24)
- Immunogenicity of isolated foetal mouse proislets. (1982) (24)
- In vivo activity of an islet-reactive T-cell clone. (1990) (24)
- The role of autoantigens in autoimmune disease. (2000) (24)
- Tissue immunogenicity: the role of MHC antigen and the lymphocyte costimulator B7-1. (1996) (24)
- The role of CD4 and CD8 T cells in the development of autoimmune diabetes. (1999) (24)
- The isolation and transplantation of foetal mouse proislets. (1982) (23)
- Transfer of sensitised Lyt 2+ cells triggers acute rejection of pancreatic islet allografts. (1983) (22)
- MECHANISM OF ENZYME INHIBITION BY ANTIBODY. A STUDY OF THE NEUTRALIZATION OF RIBONUCLEASE. (1964) (22)
- Generation of homogeneous populations of alloreactive T cells in vitro. (1979) (21)
- Immunology of graft rejection. (1984) (20)
- Fluorescein labeling of murine hepatocytes for identification after intrahepatic transplantation. (1992) (17)
- Stabilization of islet allografts by treatment of recipients with ultraviolet irradiated donor spleen cells. (1983) (17)
- Tolerance: a case of self/not-self discrimination maintained by clonal deletion? (1997) (17)
- The 12th International Immunology and Diabetes Workshop: Orlando, Florida (1993) (16)
- Effect of mycophenolate mofetil on islet allografting to chemically induced or spontaneously diabetic animals. (1992) (15)
- The allograft response. (1986) (15)
- Evidence that tolerance to cultured thyroid allografts is an active immunological process. Protection of third-party grafts bearing new antigens when associated with tolerogenic antigens. (1992) (15)
- BLOCKING OF DELIVERY OF THE ANTIGEN‐MEDIATED SIGNAL TO THE NUCLEUS OF T CELLS BY CYCLOSPORINS (1987) (15)
- Immunogenicity of mouse fetal pancreas and proislets. A comparison. (1988) (14)
- Effect of organ culture on function of transplanted foetal pancreas. (1981) (14)
- Regulation of autoimmune diabetes: Characteristics of non‐islet‐antigen specific therapies (1996) (14)
- Interaction of embryonic chicken spleen cells and adult allogeneic leucocytes. (1972) (14)
- Immunosuppressive and antiinflammatory drugs (1993) (14)
- ISLET GRAFT FUNCTION: COMPARISON OF PORTAL VERSUS SYSTEMIC VENOUS INSULIN DELIVERY (1988) (14)
- A quantitative analysis of lymphokine release from activated T cells. Evidence for a novel form of T-T collaboration in vitro. (1989) (14)
- Cytotoxic T cell responses to a syngeneic tumour: conditions for primary activation in vitro. (1978) (13)
- In vivo administration of interleukin-1 inhibits glucose-stimulated insulin release. (1989) (13)
- SURVIVAL OF PANCREATIC ISLET ALLOGRAFTS (1979) (13)
- Characteristics of lymphocyte transfer reactions produced in sheep. (1969) (12)
- Tolerance induction in adult mice: cyclosporine inhibits RS-61443-induced tolerance. (1991) (12)
- The pathogenesis of the graft-versus-host reaction in chicken embryos. Pathological changes in the yolk sac, thymus, bone marrow and bursa of Fabricius. (1972) (12)
- Autoimmune diabetes: Caught in the causality trap? (1995) (12)
- The distribution and morphology of phagocytic cells in the chiton Liolophura gaimardi. (1973) (12)
- T LYMPHOCYTE FUNCTION IN VIVO: AMBIVALENCE OF THE CLASS I MHC ANTIGEN‐REACTIVE SUBSET (1985) (12)
- DIFFERENCES IN THE GRAFT‐VERSUS-HOST REACTIVITY OF CELLS MIGRATING THROUGH NONLYMPHOID TISSUE OR LYMPH NODES (1975) (12)
- Reversal of Diabetes in Outbred Mice by Islet Allotransplantation (1986) (11)
- Pathogenesis of the graft-versus-host reaction in chicken embryos. Requirement of yolk sac-derived stem cells for the development of proliferative lesions. (1973) (11)
- Cyclosporine-induced tolerance requires antigens capable of initiating an immune response. (1987) (11)
- A conformationally-constrained MHC class II I-Ag7-derived peptide protects NOD mice from the development of diabetes. (1999) (11)
- Resistance of established islet allografts to rejection by antibody and complement. (1982) (11)
- Is there a future for fetal pancreas transplantation? (1989) (10)
- A High Frequency of Cytotoxic Precursor Cells for a Syngeneic Tumour (1979) (10)
- Lymphocyte transfer reactions and antigen mediated hypersensitivity reactions produced in the skin of sheep--a histological study. (1969) (10)
- Fetal Pancreas Transplantation for Treatment of IDDM Patients (1993) (10)
- Cytotoxic T cell responses to a syngeneic tumour: conditions for primary activation in vitro and biological activity in vivo. (1979) (9)
- Tolerance induction in adult animals: comparison of RS-61443 and anti-CD4 treatment. (1991) (9)
- A mediator acting as a costimulator for the development of cytotoxic responses in vitro. (1979) (9)
- Pathogenesis of the graft-versus-host reaction in chicken embryos. The development of haemorrhagic lesions. (1973) (9)
- Fine structure of phagocytic cells in the chiton, Liolophura gaimardi. (1973) (9)
- Pancreatic Islet and Proislet Transplantation in the Mouse Model (1998) (9)
- Interleukin 2 production by alloantigen (H-2) activated T cells. (1981) (9)
- Theory and practice of immunoregulation by tissue treatment prior to transplantation (1984) (8)
- Tolerance Induction in Adult Animals (1986) (8)
- Current status of experimental islet transplantation. (1984) (8)
- Sensitized Lyt-2+ T cells trigger rejection of grafts expressing class I major histocompatibility complex alloantigens. (1986) (8)
- ALLOGENEIC STIMULATION MODULATES THE STRENGTH OF TRANSPLANTATION ANTIGEN (1974) (8)
- Spontaneous tolerance induction in adult animals transplanted with allogeneic islets. (1988) (8)
- A quantitative analysis of antigen-triggered lymphokine production by activated T cells. (1987) (7)
- The Pathogenesis of Immunologically Mediated Diabetes (1990) (7)
- Immunogenicity of foreign tissues. (1980) (7)
- AN ANALYSIS OF TISSUE‐SPECIFIC TRANSPLANTATION PHENOMENA IN A MINOR HISTOINCOMPATIBILITY SYSTEM (1985) (7)
- The flow and cellular composition of cervical lymph from unanaesthetized ducks. (1972) (7)
- Effect of human fetal pancreas transplantation on secretion of C-peptide and glucose tolerance in type I diabetics. (1987) (7)
- Nature of tolerance induction to peripheral (extrathymic) islet allografts. (1994) (7)
- Role of gamma-interferon in islet allograft rejection: class I MHC antigen induction. (1989) (7)
- The immunologic network. (1988) (6)
- THE RELATIONSHIP BETWEEN MOLECULAR CHARGE AND THE BIOLOGICAL ACTIVITY OF ANTIBODY DIRECTED AGAINST RABBITPOX VIRUS. (1965) (6)
- Cyclosporine A and the regulation of autoimmune disease (1988) (6)
- Immunobiology of autoimune diabetes (1997) (6)
- A few steps along the path to adult transplantation tolerance. (1999) (6)
- Control of diabetes: comparative immunogenicity and function of fetal pancreas and isolated islets. (1984) (6)
- Influence of embryo age on the expression of the GvH reaction in the chicken embryo. (1971) (6)
- Theory of allogeneic reactivity and its relevance to transplantation biology. (1976) (5)
- Letter: Cellular proliferation can be an unreliable index of immune competence. (1974) (5)
- Islet allografting without immunosuppression: reversal of insulitis-associated diabetes and a case of spontaneous juvenile onset diabetes in mice. (1982) (5)
- The role of CD 4 ' and CD 8 ' T cells in the . destruction of islet grafts by spontaneously diabetic mice ( nonobese diabetic mice / diabetes / transplantation / autoimmumty ) (5)
- Pathogenesis of Autoimmune Diabetes (1994) (5)
- Is a specialized stimulator cell required for the induction of allograft immunity? (1976) (5)
- Antigen presentation and effector mechanisms in ‘auto‐immune’ diabetes (1991) (4)
- The dermal reaction induced in sheep by homologous lymphocytes and an RNA fraction extracted from homologous lymphocytes. (1968) (4)
- A Novel Form of T‐T Collaboration Requiring the Active Participation of the Antigen‐Presenting Cell (1988) (4)
- Active and Passive Antigen Presentation: Its Role in the Induction of Tissue Immunity and Allograft Tolerance (1986) (4)
- Approaches to the prevention of immune destruction of transplanted pancreatic islets. (1994) (4)
- Cellular requirements for production and release of the lymphocyte costimulator. (1980) (3)
- Induction of tolerance using ultraviolet-irradiated cells. (1984) (3)
- A contemporary view of transplantation tolerance: an immunologist's perspective. (1994) (3)
- Purified hepatic parenchymal cells are nonimmunogenic in vitro. (1995) (3)
- Transplantation editorial overview Antigen, co-stimulators and cytokines: regulators of allogeneic interactions (1993) (3)
- Is There a Role for Antibody in the Pathogenesis of Spontaneous Diabetes in the BB Rat? (1986) (3)
- Reversal of diabetes by proislet isotransplantation. (1985) (3)
- Lethal effect of the intravenous injection of H-2 alloantigen activated T cells. (1982) (3)
- Ectopic class II MHC antigen expression and the development of diabetes. (1990) (3)
- Rapid Publication Combined Treatment With Nicotinamide and Desferrioxamine Prevents Islet Al log raft Destruction in NOD Mice (1986) (3)
- Cytotoxic t cell mediated graft rejection is lymphokine dependent (1985) (3)
- Immunobiology of autoimmune diabetes. (1997) (3)
- Syngeneic Transplantation of Cryopreserved Fetal Mouse Proislets (1984) (3)
- Pancreatic islet transplantation--experimental experience and clinical potential. (1985) (3)
- Differences in genetic specificity are observed when spleen and lymph node leucocytes are used as the responsive cell population in mixed leucocyte cultures. (1974) (3)
- Cyclosporine A: a tool for analyzing the function of class I MHC antigen-reactive T cells in vivo. (1984) (2)
- Separation and characterization of cells produced by the antigenically stimulated lymph node. (1970) (2)
- Antigen, Cytokines, and the Regulation of the Allograft Response (1989) (2)
- Survival and function of islet allografts in outbred mice. (1986) (2)
- The Role of Islet Transplantation in the Treatment of Insulin-dependent Diabetes Mellitus (1989) (2)
- An Alternate Mechanism for Immune Recognition (1973) (1)
- Beta-cell replacement (1997) (1)
- Superoxide radical is involved in expression of “autoimmune” diabetes in the NOD mouse (1990) (1)
- Lyt-2+ cells sensitized to graft alloantigens trigger the rejection of established cultured pancreatic islet allografts. (1984) (1)
- Tolerance induction in adult animals. The ciclosporin anomaly. (1986) (1)
- The effect of molecular charge on the uptake of protein by cultured mammalian cells. (1971) (1)
- Plenary sessions: 5. Current concepts in tumour immunologyK. Lafferty (1979) (1)
- The neutralization of animal viruses (1960) (1)
- Theory of allogeneic reactivity and its relevance to the T-cell response to normal and oncogenic cells. (1976) (0)
- IDDM in the NOD mouse follows a late change in the autoimmune T-cell response (2009) (0)
- Burnet oration. Politics, personalities and the development of science. (1995) (0)
- Mechanism of self-tolerance to endocrine tissue (2004) (0)
- THE NATURE OF THE ALLOGRAFT REACTION (1977) (0)
- Enrichment of Beta cells from the human fetal pancreas by fluorescence activated cell sorting with a new monoclonal antibody (1992) (0)
- Transplantation. Antigen, co-stimulators and cytokines: regulators of allogeneic interactions. (1993) (0)
- Pathogenesis of spontaneous diabetes in the BB rat: is there a role for antibody? (1986) (0)
- Defining the limits of organ and tissue research and transplantation. (1993) (0)
- Analysis of T cell function using cyclosporine: graft rejection by T cells involves lymphokine release. (1985) (0)
- High-Tech Medicine Pancreatic Islet Transplantation-Experimental Experience and Clinical Potential (2005) (0)
- CD4 T cells and allograft rejection. (1988) (0)
- Second Congress of the Immunology of Diabetes Society (formerly the 15th Immunology of Diabetes Workshop) held in Canberra, Australia, 8–11 December 1996: Introduction (1997) (0)
- Politics, personalities and the development of science (1995) (0)
- Second Congress of the Immunology of Diabetes Society, 8-11 December, 1996 : abstracts (1996) (0)
- Legal and medical implications of fetal tissue transplantation. (1993) (0)
- Immunogenic properties of fetal mouse proislets. (1987) (0)
- Beta-cell replacement (1997) (0)
- Produced by mitogen-activated lymphocytes. (1980) (0)
- Regulation of lymphokine release involving a novel form of T-T collaboration. (1989) (0)
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