Kenneth J. Marians
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Kenneth J. Marians's AcademicInfluence.com Rankings
Kenneth J. Mariansbiology Degrees
Biology
#12425
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#15900
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Molecular Biology
#2012
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#2044
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Biochemistry
#2109
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#2253
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Biology
Kenneth J. Marians's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Chemistry University of California, Berkeley
Why Is Kenneth J. Marians Influential?
(Suggest an Edit or Addition)Kenneth J. Marians's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The importance of repairing stalled replication forks (2000) (1042)
- Coupling of a Replicative Polymerase and Helicase: A τ–DnaB Interaction Mediates Rapid Replication Fork Movement (1996) (350)
- DNA gyrase and topoisomerase IV: biochemical activities, physiological roles during chromosome replication, and drug sensitivities. (1998) (346)
- Replication fork reactivation downstream of a blocked nascent leading strand (2006) (319)
- Prokaryotic DNA replication. (1992) (308)
- Replisome assembly and the direct restart of stalled replication forks (2006) (283)
- Escherichia coli topoisomerase IV. Purification, characterization, subunit structure, and subunit interactions. (1993) (251)
- Role of PriA in Replication Fork Reactivation inEscherichia coli (2000) (213)
- Rescuing stalled or damaged replication forks. (2013) (198)
- The DNA replication protein PriA and the recombination protein RecG bind D-loops. (1997) (192)
- PriA-directed replication fork restart in Escherichia coli. (2000) (185)
- Identification of a potent decatenating enzyme from Escherichia coli. (1988) (179)
- The Structure of Supercoiled Intermediates in DNA Replication (1998) (170)
- Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. I. Multiple effectors act to modulate Okazaki fragment size. (1992) (170)
- Inactivation of the Escherichia coli priA DNA replication protein induces the SOS response (1991) (165)
- Formation of Holliday junctions by regression of nascent DNA in intermediates containing stalled replication forks: RecG stimulates regression even when the DNA is negatively supercoiled (2001) (152)
- The Interaction between Helicase and Primase Sets the Replication Fork Clock* (1996) (149)
- The disposition of nascent strands at stalled replication forks dictates the pathway of replisome loading during restart. (2005) (144)
- Identification of a domain of Escherichia coli primase required for functional interaction with the DnaB helicase at the replication fork. (1994) (138)
- Decatenation activity of topoisomerase IV during oriC and pBR322 DNA replication in vitro. (1993) (132)
- Replication fork assembly at recombination intermediates is required for bacterial growth. (1999) (132)
- The Escherichia coli Replisome Is Inherently DNA Damage Tolerant (2011) (132)
- Resolution of converging replication forks by RecQ and topoisomerase III. (2008) (132)
- The Escherichia coli preprimosome and DNA B helicase can form replication forks that move at the same rate. (1987) (131)
- DNA Strand Cleavage Is Required for Replication Fork Arrest by a Frozen Topoisomerase-Quinolone-DNA Ternary Complex* (1996) (126)
- Structure of the SSB–DNA polymerase III interface and its role in DNA replication (2011) (125)
- ATPase-deficient mutants of the Escherichia coli DNA replication protein PriA are capable of catalyzing the assembly of active primosomes. (1992) (125)
- Independent and Stochastic Action of DNA Polymerases in the Replisome (2017) (121)
- Decatenating activity of Escherichia coli DNA gyrase and topoisomerases I and III during oriC and pBR322 DNA replication in vitro. (1994) (117)
- PriA mediates DNA replication pathway choice at recombination intermediates. (2003) (116)
- A Physical and Functional Interaction between Escherichia coli FtsK and Topoisomerase IV* (2003) (115)
- τCouples the Leading- and Lagging-strand Polymerases at the Escherichia coli DNA Replication Fork* (1996) (112)
- Escherichia coli Tus protein acts to arrest the progression of DNA replication forks in vitro. (1990) (112)
- Lesion Bypass and the Reactivation of Stalled Replication Forks. (2018) (111)
- Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. V. Primase action regulates the cycle of Okazaki fragment synthesis. (1992) (110)
- Temporal regulation of topoisomerase IV activity in E. coli. (2003) (106)
- Untangling intracellular DNA topology (2004) (105)
- Molecular cloning and DNA sequence analysis of Escherichia coli topB, the gene encoding topoisomerase III. (1989) (102)
- Two Distinct Modes of Strand Unlinking during θ-Type DNA Replication* (1996) (100)
- Physical and functional interaction between the condensin MukB and the decatenase topoisomerase IV in Escherichia coli (2010) (100)
- The ordered assembly of the phiX174-type primosome. I. Isolation and identification of intermediate protein-DNA complexes. (1996) (99)
- Replication of pBR322 DNA in vitro with purified proteins. Requirement for topoisomerase I in the maintenance of template specificity. (1985) (98)
- Recruitment to stalled replication forks of the PriA DNA helicase and replisome-loading activities is essential for survival. (2010) (97)
- Replication and recombination intersect. (2000) (96)
- Escherichia coli replication factor Y, a component of the primosome, can act as a DNA helicase. (1987) (94)
- A general method for inserting specific DNA sequences into cloning vehicles. (1976) (90)
- Unwinding of the Nascent Lagging Strand by Rep and PriA Enables the Direct Restart of Stalled Replication Forks*[boxs] (2005) (86)
- The Interaction of Escherichia coli Topoisomerase IV with DNA (*) (1995) (85)
- The ordered assembly of the phiX174-type primosome. III. PriB facilitates complex formation between PriA and DnaT. (1996) (82)
- Topoisomerase III Can Serve as the Cellular Decatenase in Escherichia coli * (2003) (80)
- The Extreme C Terminus of Primase Is Required for Interaction with DnaB at the Replication Fork* (1996) (76)
- Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. II. Frequency of primer synthesis and efficiency of primer utilization control Okazaki fragment size. (1992) (75)
- Protein–DNA complexes are the primary sources of replication fork pausing in Escherichia coli (2013) (72)
- Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. III. A polymerase-primase interaction governs primer size. (1992) (71)
- Topoisomerase III, but not topoisomerase I, can support nascent chain elongation during theta-type DNA replication. (1994) (70)
- The ordered assembly of the phiX174-type primosome. II. Preservation of primosome composition from assembly through replication. (1996) (70)
- Two Distinct Triggers for Cycling of the Lagging Strand Polymerase at the Replication Fork* (2000) (69)
- Tus prevents overreplication of oriC plasmid DNA. (1994) (68)
- PriA: at the crossroads of DNA replication and recombination. (1999) (68)
- Mechanisms of replication fork restart in Escherichia coli. (2004) (68)
- Dynamics of leading-strand lesion skipping by the replisome. (2013) (67)
- DNA gyrase-catalyzed decatenation of multiply linked DNA dimers. (1987) (64)
- Coordinated leading- and lagging-strand synthesis at the Escherichia coli DNA replication fork. IV. Reconstitution of an asymmetric, dimeric DNA polymerase III holoenzyme. (1992) (61)
- Phi X174-type primosomal proteins: purification and assay. (1995) (60)
- Characterization of the unique C terminus of the Escherichia coli tau DnaX protein. Monomeric C-tau binds alpha AND DnaB and can partially replace tau in reconstituted replication forks. (2000) (59)
- Molecular cloning and DNA sequence analysis of Escherichia coli priA, the gene encoding the primosomal protein replication factor Y. (1990) (58)
- Cloned synthetic lac operator DNA is biologically active (1976) (57)
- Role of the Core DNA Polymerase III Subunits at the Replication Fork (1998) (55)
- Topoisomerase IV can support oriC DNA replication in vitro. (1994) (53)
- Actin homolog MreB affects chromosome segregation by regulating topoisomerase IV in Escherichia coli. (2009) (53)
- Dissecting the functional role of PriA protein‐catalysed primosome assembly in Escherichia coli DNA replication (1991) (51)
- Identification of two Escherichia coli factor Y effector sites near the origins of replication of the plasmids (ColE1 and pBR322. (1980) (51)
- Protects in the Leading-strand Polymerase Complex at the Replication Fork (*) (1996) (51)
- Role of DNA gyrase in phiX replicative-form replication in vitro. (1977) (49)
- Differential inhibition of the DNA translocation and DNA unwinding activities of DNA helicases by the Escherichia coli Tus protein. (1992) (48)
- Non-replicative helicases at the replication fork. (2007) (48)
- Primase couples leading- and lagging-strand DNA synthesis from oriC. (1994) (48)
- Identification of a Region of Escherichia coli DnaB Required for Functional Interaction with DnaG at the Replication Fork* (2000) (47)
- A role for topoisomerase III in Escherichia coli chromosome segregation (2012) (45)
- Helicase-deficient cysteine to glycine substitution mutants of Escherichia coli replication protein PriA retain single-stranded DNA-dependent ATPase activity. Zn2+ stimulation of mutant PriA helicase and primosome assembly activities. (1993) (42)
- Identification of a unique domain essential for Escherichia coli DNA topoisomerase III‐catalysed decatenation of replication intermediates (2000) (42)
- Chemical synthesis and sequence studies of deoxyribooligonucleotides which constitute the duplex sequence of the lactose operator of Escherichia coli. (1975) (41)
- Maximal limits of the Escherichia coli replication factor Y effector site sequences in pBR322 DNA. (1982) (40)
- Escherichia coli topoisomerase III-catalyzed cleavage of RNA. (1992) (40)
- On the statistical significance of primary structural features found in DNA-protein interaction sites. (1975) (39)
- Two distinct modes of strand unlinking during theta-type DNA replication. (1996) (38)
- Mechanism of DNA A protein-dependent pBR322 DNA replication. DNA A protein-mediated trans-strand loading of the DNA B protein at the origin of pBR322 DNA. (1991) (37)
- Escherichia coli factor Y sites of plasmid pBR322 can function as origins of DNA replication. (1981) (36)
- The priB and priC replication proteins of Escherichia coli. Genes, DNA sequence, overexpression, and purification. (1991) (36)
- Crawling and wiggling on DNA: structural insights to the mechanism of DNA unwinding by helicases. (2000) (35)
- Enzymology of DNA in Replication in Prokaryote (1984) (35)
- A Dynamic RecA Filament Permits DNA Polymerase-catalyzed Extension of the Invading Strand in Recombination Intermediates* (2002) (35)
- DNA chirality-dependent stimulation of topoisomerase IV activity by the C-terminal AAA+ domain of FtsK (2010) (35)
- The Escherichia coli primosome can translocate actively in either direction along a DNA strand. (1989) (35)
- Initiation of Bidirectional Replication at the Chromosomal Origin Is Directed by the Interaction between Helicase and Primase* (1999) (34)
- Fis cannot support oriC DNA replication in vitro. (1994) (34)
- Escherichia coli topoisomerase I can segregate replicating pBR322 daughter DNA molecules in vitro. (1986) (33)
- The MukB-ParC Interaction Affects the Intramolecular, Not Intermolecular, Activities of Topoisomerase IV* (2013) (33)
- Purification and Characterization of DnaC810, a Primosomal Protein Capable of Bypassing PriA Function* (2000) (33)
- Replisome-mediated Translesion Synthesis and Leading Strand Template Lesion Skipping Are Competing Bypass Mechanisms* (2014) (33)
- Purification and Characterization of Escherichia coli MreB Protein* (2012) (31)
- Topoisomerase III Acts at the Replication Fork To Remove Precatenanes (2019) (31)
- Differential ATP requirements distinguish the DNA translocation and DNA unwinding activities of the Escherichia coli PRI A protein. (1990) (30)
- Formation of rolling-circle molecules during phi X174 complementary strand DNA replication. (1987) (29)
- Regression of Replication Forks Stalled by Leading-strand Template Damage (2014) (28)
- Helicase structures: a new twist on DNA unwinding. (1997) (27)
- Mechanism of Quinolone Action A DRUG-INDUCED STRUCTURAL PERTURBATION OF THE DNA PRECEDES STRAND CLEAVAGE BY TOPOISOMERASE IV* (1997) (27)
- The bacterial condensin MukB compacts DNA by sequestering supercoils and stabilizing topologically isolated loops (2017) (25)
- Mutational analysis of primosome assembly sites. I. Distinct classes of mutants in the pBR322 Escherichia coli factor Y DNA effector sequences. (1984) (24)
- Understanding how the replisome works (2008) (23)
- DNA Polymerase III from Escherichia coliCells Expressing mutA Mistranslator tRNA Is Error-prone* (2002) (23)
- The Ordered Assembly of the φX174-type Primosome (1996) (22)
- Identification of dnaX as a High-Copy Suppressor of the Conditional Lethal and Partition Phenotypes of theparE10 Allele (1998) (21)
- Replication of superhelical DNAs in vitro. (1986) (20)
- Regression of Replication Forks Stalled by Leading-strand Template Damage (2014) (19)
- Enzymology of DNA in replication in prokaryotes. (1984) (17)
- Timely Release of Both Replication Forks from oriCRequires Modulation of Origin Topology* (2001) (17)
- Characterization of the Nucleoid-associated Protein YejK* (2013) (16)
- Replisome-mediated translesion synthesis by a cellular replicase (2017) (16)
- The MukB–topoisomerase IV interaction is required for proper chromosome compaction (2017) (15)
- Deletion mutants defining the Escherichia coli replication factor Y effector site sequences in pBR322 DNA. (1982) (14)
- Mutational analysis of primosome assembly sites. II. Role of secondary structure in the formation of active sites. (1984) (14)
- Enzymatic techniques for the isolation of random single-base substitutions in vitro at high frequency. (1984) (14)
- Replication of phiX174 DNA: in vitro synthesis of phiX RFI DNA and circular, single-stranded DNA. (1979) (14)
- Mutations in the Escherichia coli Tus Protein Define a Domain Positioned Close to the DNA in the Tus-Ter Complex (*) (1995) (14)
- Mutational analysis of primosome assembly sites. Evidence for alternative DNA structures. (1985) (13)
- Replisome bypass of transcription complexes and R-loops (2020) (13)
- The interaction of Escherichia coli replication factor Y with complementary strand origins of DNA replication. Contact points revealed by DNase footprinting and protection from methylation. (1984) (13)
- Transcriptional activation of pBR322 DNA can lead to duplex DNA unwinding catalyzed by the Escherichia coli preprimosome. (1989) (13)
- MukB-mediated Catenation of DNA Is ATP and MukEF Independent* (2016) (12)
- Mutational analysis of Escherichia coli topoisomerase IV. III. Identification of a region of parE involved in covalent catalysis. (2000) (12)
- The Ordered Assembly of the fX174-type Primosome I. ISOLATION AND IDENTIFICATION OF INTERMEDIATE PROTEIN-DNA COMPLEXES* (1996) (11)
- Overexpression and purification of bacterial topoisomerase IV. (1999) (11)
- Mutational analysis of Escherichia coli topoisomerase IV. II. ATPase negative mutants of parE induce hyper-DNA cleavage. (2000) (11)
- Mutational analysis of Escherichia coli topoisomerase IV. I. Selection of dominant-negative parE alleles. (2000) (10)
- Structure of the lactose operator (1976) (10)
- N-Terminal Amino Acid Sequence Determination of Proteins by N-Terminal Dimethyl Labeling: Pitfalls and Advantages When Compared with Edman Degradation Sequence Analysis. (2016) (9)
- Studies on the lactose operon. III. Visualization and physical mapping of the lactose repressor-operator complex. (1976) (8)
- Two components of DNA replication-dependent LexA cleavage (2020) (7)
- Rescuing US biomedical research: Some comments on Alberts, Kirschner, Tilghman, and Varmus (2014) (7)
- The MukB-topoisomerase IV interaction mutually suppresses their catalytic activities (2021) (7)
- The recombination mediator proteins RecFOR maintain RecA* levels for maximal DNA polymerase V Mut activity (2018) (6)
- Replication Fork Propagation in Escherichia coli (1989) (6)
- DNA and RNA-DNA annealing activity associated with the tau subunit of the Escherichia coli DNA polymerase III holoenzyme. (1995) (6)
- The Ordered Assembly of the φX174-type Primosome (1996) (6)
- Bypass of complex co-directional replication-transcription collisions by replisome skipping (2021) (5)
- The Ordered Assembly of the φX174-type Primosome (1996) (2)
- Ribo-substitution at the ends of duplex DNA: complete nucleotide sequence of the right-hand cohesive end of coliphage 186 DNA. (1975) (2)
- Characterization of the Unique C Terminus of theEscherichia coli τ DnaX Protein (2000) (2)
- Intersubunit and intrasubunit interactions driving the MukBEF ATPase (2022) (2)
- Dissecting DNA Compaction by the Bacterial Condensin MukB. (2019) (2)
- Studies on the In Vitro Synthesis of ϕ X174 RFI DNA and Circular Single-stranded DNA (1978) (2)
- Direct visualization of translesion DNA synthesis polymerase IV at the replisome (2022) (1)
- Additions and Corrections to The ordered assembly of the ϕX174-type primosome. I. Isolation and identification of intermediate protein-DNA complexes. (1996) (1)
- Mutational Analysis of Escherichia coliTopoisomerase IV (2000) (1)
- Mutational Analysis of Escherichia coliTopoisomerase IV (2000) (1)
- DNA sequence analysis of Escherichia coli pa & and parE , encoding the subunits of topoisomerase IV ( Top 0 (2001) (0)
- Procede de replication d'adn (2000) (0)
- Inter- and intra-Subunit interactions driving the MukBEF ATPase (2022) (0)
- Chemical Synthesis and Sequence Studies of Deoxyribooligonucleotides which Constitute the Duplex Sequence of the Lactose (1975) (0)
- Replication Hits 50 (2005) (0)
- The importance of repairing stalled replication fork replication forks (2000) (0)
- Escherichia coli Reactivation in Role of PriA in Replication Fork (1999) (0)
- Purification and Characterization of Escherichia coli MreB* (2012) (0)
- "us Prevents Overreplication of oriC Plasmid DNA* (2001) (0)
- Preliminary crystallographic analysis of the ParE subunit of Escherichia coli topoisomerase IV. (1996) (0)
- Mutational Analysis of Escherichia coliTopoisomerase IV (2000) (0)
- Jerard Hurwitz (1928–2019) (2019) (0)
- A role for topoisomerase III in Escherichia coli chromosome segregation (2012) (0)
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