Kenneth S. Polonsky
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Kenneth S. Polonsky's Degrees
- PhD Biochemistry University of Chicago
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(Suggest an Edit or Addition)Kenneth S. Polonsky's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3) (1996) (1567)
- International trial of the Edmonton protocol for islet transplantation. (2006) (1482)
- Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus (2000) (1464)
- Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. (2001) (1078)
- Estimation of Insulin Secretion Rates from C-Peptide Levels: Comparison of Individual and Standard Kinetic Parameters for C-Peptide Clearance (1992) (864)
- Twenty-four-hour profiles and pulsatile patterns of insulin secretion in normal and obese subjects. (1988) (720)
- The Diabetes Prevention Program. Design and methods for a clinical trial in the prevention of type 2 diabetes. (1999) (625)
- Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus. (1988) (607)
- Seminars in Medicine of the Beth Israel Hospital, Boston. Non-insulin-dependent diabetes mellitus - a genetically programmed failure of the beta cell to compensate for insulin resistance. (1996) (604)
- Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component. (2002) (583)
- Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat. (1998) (574)
- Roles of circadian rhythmicity and sleep in human glucose regulation. (1997) (536)
- Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome. (1997) (510)
- C-Peptide as a Measure of the Secretion and Hepatic Extraction of Insulin: Pitfalls and Limitations (1984) (491)
- C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve beta-cell function: report of an ADA workshop, 21-22 October 2001. (2004) (462)
- Quantitative study of insulin secretion and clearance in normal and obese subjects. (1988) (460)
- Diabetes mellitus and genetically programmed defects in β-cell function (2001) (456)
- Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus. (1995) (446)
- β-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment (2014) (402)
- Modulation of glucose regulation and insulin secretion by circadian rhythmicity and sleep. (1991) (391)
- Relative effects of calorie restriction and weight loss in noninsulin-dependent diabetes mellitus. (1993) (369)
- Interactions between insulin resistance and insulin secretion in the development of glucose intolerance. (2000) (358)
- The Diabetes Prevention Program: baseline characteristics of the randomized cohort. The Diabetes Prevention Program Research Group. (2000) (349)
- Increased islet apoptosis in Pdx1+/- mice. (2003) (341)
- Defective insulin secretion in hepatocyte nuclear factor 1alpha-deficient mice. (1998) (339)
- Regulation of pancreatic β-cell growth and survival by the serine/threonine protein kinase Akt1/PKBα (2001) (330)
- Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome. (1997) (318)
- Aldose reductase inhibition improves nerve conduction velocity in diabetic patients. (1983) (316)
- Metabolic Effects of Troglitazone Monotherapy in Type 2 Diabetes Mellitus (1998) (314)
- Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency. (2003) (313)
- Regulation of pancreatic beta-cell growth and survival by the serine/threonine protein kinase Akt1/PKBalpha. (2001) (289)
- Oral Glucose Tolerance Test Minimal Model Indexes of β-Cell Function and Insulin Sensitivity (2001) (283)
- Insulin signaling in alpha cells modulates glucagon secretion in vivo. (2009) (278)
- The past 200 years in diabetes. (2012) (268)
- Altered Insulin Secretory Responses to Glucose in Diabetic and Nondiabetic Subjects With Mutations in the Diabetes Susceptibility Gene MODY3 on Chromosome 12 (1996) (267)
- Computer model for mechanisms underlying ultradian oscillations of insulin and glucose. (1991) (243)
- Plasma insulin, C-peptide, and proinsulin concentrations in obese and nonobese individuals with varying degrees of glucose tolerance. (1993) (240)
- Visualizing Superoxide Production in Normal and Diabetic Rat Islets of Langerhans* (2003) (237)
- Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism. (2001) (234)
- Defects in beta-cell function in functional ovarian hyperandrogenism. (1993) (234)
- Circadian modulation of glucose and insulin responses to meals: relationship to cortisol rhythm. (1992) (230)
- Defective insulin secretion and increased susceptibility to experimental diabetes are induced by reduced Akt activity in pancreatic islet beta cells. (2004) (228)
- Diabetes mellitus and genetically programmed defects in beta-cell function. (2001) (224)
- Brief report: impaired processing of prohormones associated with abnormalities of glucose homeostasis and adrenal function. (1995) (221)
- Metabolic effects of short-term elevations of plasma cortisol are more pronounced in the evening than in the morning. (1999) (219)
- Fasting hypertriglyceridemia in noninsulin-dependent diabetes mellitus is an important predictor of postprandial lipid and lipoprotein abnormalities. (1991) (216)
- Treatment with the oral antidiabetic agent troglitazone improves beta cell responses to glucose in subjects with impaired glucose tolerance. (1997) (213)
- Evolution of β-Cell Dysfunction in the Male Zucker Diabetic Fatty Rat (1995) (202)
- Pdx1 and other factors that regulate pancreatic β‐cell survival (2009) (194)
- Insulin protects islets from apoptosis via Pdx1 and specific changes in the human islet proteome (2006) (193)
- Increased beta-cell proliferation and reduced mass before diabetes onset in the nonobese diabetic mouse. (1999) (191)
- Report of the American Diabetes Association's Task Force on Standardization of the Insulin Assay (1996) (187)
- Leptin, the obese gene product, rapidly modulates synaptic transmission in the hypothalamus. (1996) (185)
- Calpains play a role in insulin secretion and action. (2001) (182)
- Free fatty acids impair hepatic insulin extraction in vivo. (1999) (180)
- Postprandial lipoprotein metabolism in normal and obese subjects: comparison after the vitamin A fat-loading test. (1990) (179)
- Ultradian oscillations of leptin secretion in humans. (1996) (178)
- Natural history of intrahepatic canine islet cell autografts. (1986) (175)
- Recruitment of bone marrow-derived endothelial cells to sites of pancreatic beta-cell injury. (2004) (174)
- Metabolism of C-peptide in the dog. In vivo demonstration of the absence of hepatic extraction. (1983) (171)
- Defects in Insulin Secretion and Action in Women With a History of Gestational Diabetes (1995) (169)
- Transgenic studies with a keratin promoter-driven growth hormone transgene: prospects for gene therapy. (1997) (168)
- Oral glucose tolerance test minimal model indexes of beta-cell function and insulin sensitivity. (2001) (165)
- Carboxypeptidase E mediates palmitate-induced β-cell ER stress and apoptosis (2008) (162)
- Two-hour seven-sample oral glucose tolerance test and meal protocol: minimal model assessment of beta-cell responsivity and insulin sensitivity in nondiabetic individuals. (2005) (162)
- Targeted Ablation of Glucose-dependent Insulinotropic Polypeptide-producing Cells in Transgenic Mice Reduces Obesity and Insulin Resistance Induced by a High Fat Diet* (2008) (161)
- Defective Pancreatic β-Cell Glycolytic Signaling in Hepatocyte Nuclear Factor-1α-deficient Mice* (1998) (160)
- Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO mice (2004) (158)
- RyR2 and Calpain-10 Delineate a Novel Apoptosis Pathway in Pancreatic Islets* (2004) (152)
- TCF7L2 Variant rs7903146 Affects the Risk of Type 2 Diabetes by Modulating Incretin Action (2009) (152)
- Twenty-four-hour leptin levels respond to cumulative short-term energy imbalance and predict subsequent intake. (2000) (148)
- The β-Cell in Diabetes: From Molecular Genetics to Clinical Research (1995) (147)
- Maturity-onset diabetes of the young. (1995) (140)
- Altered Insulin Secretory Responses to Glucose in Subjects with a Mutation in the MODY1 Gene on Chromosome 20 (1995) (138)
- Apoptosis in insulin-secreting cells. Evidence for the role of intracellular Ca2+ stores and arachidonic acid metabolism. (1998) (137)
- Ginseng berry reduces blood glucose and body weight in db/db mice. (2002) (136)
- Prevention of hyperglycemia in the Zucker diabetic fatty rat by treatment with metformin or troglitazone. (1996) (135)
- Erratum: C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve β-cell function: Report of an ADA workshop, 21-22 October 2001 (Diabetes (2004) 53 (250-264)) (2004) (134)
- Oscillations in insulin secretion during constant glucose infusion in normal man: relationship to changes in plasma glucose. (1988) (133)
- Low acute insulin secretory responses in adult offspring of people with early onset type 2 diabetes. (2001) (131)
- The Limitations to and Valid Use of C-Peptide as a Marker of the Secretion of Insulin (1986) (131)
- Alterations in the glucose-stimulated insulin secretory dose-response curve and in insulin clearance in nondiabetic insulin-resistant individuals. (1997) (130)
- Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat. (1995) (129)
- Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus. (1993) (127)
- Effects of morning cortisol elevation on insulin secretion and glucose regulation in humans. (1996) (127)
- β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment. (2014) (125)
- Effects of Aging on Insulin Secretion (1989) (123)
- Dysregulation of insulin secretion in children with congenital hyperinsulinism due to sulfonylurea receptor mutations. (2001) (120)
- C-peptide and insulin secretion. Relationship between peripheral concentrations of C-peptide and insulin and their secretion rates in the dog. (1984) (118)
- Roles of insulin resistance and obesity in regulation of plasma insulin concentrations. (2000) (117)
- The Effects of Biosynthetic Human Proinsulin on Carbohydrate Metabolism (1984) (116)
- Insulin sensitivity by oral glucose minimal models: validation against clamp. (2005) (116)
- Abnormal Insulin Secretion, Not Insulin Resistance, Is the Genetic or Primary Defect of MODY in the RW Pedigree (1994) (115)
- Autophagy Regulates Pancreatic Beta Cell Death in Response to Pdx1 Deficiency and Nutrient Deprivation* (2009) (115)
- Increase in serum leptin and uterine leptin receptor messenger RNA levels during pregnancy in rats. (1997) (114)
- Reduced beta-cell mass and altered glucose sensing impair insulin-secretory function in betaIRKO mice. (2004) (114)
- Tumor hypoglycemia: relationship to high molecular weight insulin-like growth factor-II. (1990) (108)
- Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion. (2000) (108)
- Entrainment of pulsatile insulin secretion by oscillatory glucose infusion. (1991) (105)
- Quantitative indexes of beta-cell function during graded up&down glucose infusion from C-peptide minimal models. (2001) (105)
- Expression of Calcium Channel mRNAs in Rat Pancreatic Islets and Downregulation After Glucose Infusion (1993) (104)
- Dose-dependent effects of oral and intravenous glucose on insulin secretion and clearance in normal humans. (1988) (102)
- Familial hyperinsulinemia due to a structurally abnormal insulin. Definition of an emerging new clinical syndrome. (1984) (101)
- Variable Deterioration in Cortical Function During Insulin-induced Hypoglycemia (1985) (100)
- Insulin secretion and clearance during low-dose graded glucose infusion. (1995) (99)
- Glucokinase mutations, insulin secretion, and diabetes mellitus. (1996) (97)
- In vivo pulsatility of pancreatic islet peptides. (1986) (97)
- Role of basal triglyceride and high density lipoprotein in determination of postprandial lipid and lipoprotein responses. (1992) (96)
- Calculated Pattern of Intraportal Insulin Appearance Without Independent Assessment of C-Peptide Kinetics (1987) (96)
- Reduced Expression of the Insulin Receptor in Mouse Insulinoma (MIN6) Cells Reveals Multiple Roles of Insulin Signaling in Gene Expression, Proliferation, Insulin Content, and Secretion* (2005) (93)
- Ryanodine receptors in human pancreatic β cells: localization and effects on insulin secretion (2004) (90)
- Insulin Secretion and Clearance: Comparison After Oral and Intravenous Glucose (1987) (87)
- Standardization of C-peptide measurements. (2008) (85)
- Lilly Lecture 1994. The beta-cell in diabetes: from molecular genetics to clinical research. (1995) (85)
- Relation of counterregulatory responses to hypoglycemia in type I diabetics. (1982) (80)
- Reduction in Portal Vein Blood Flow by Somatostatin (1979) (79)
- Targeting cyclophilin D and the mitochondrial permeability transition enhances β-cell survival and prevents diabetes in Pdx1 deficiency (2010) (78)
- Glucose ingestion in dogs alters the hepatic extraction of insulin. In vivo evidence for a relationship between biologic action and extraction of insulin. (1982) (76)
- Comprar Williams Textbook of Endocrinology, 12th Edition Expert Consult | Henry M. Kronenberg | 9781437703245 | Saunders (2011) (76)
- Kir6.2 Variant E23K Increases ATP-Sensitive K+ Channel Activity and Is Associated With Impaired Insulin Release and Enhanced Insulin Sensitivity in Adults With Normal Glucose Tolerance (2009) (76)
- Elevated plasma glucose 2 h postchallenge predicts defects in beta-cell function. (1996) (75)
- Differences in the hepatic and renal extraction of insulin and glucagon in the dog: evidence for saturability of insulin metabolism. (1983) (75)
- Ginseng and Ginsenoside Re Do Not Improve β-Cell Function or Insulin Sensitivity in Overweight and Obese Subjects With Impaired Glucose Tolerance or Diabetes (2011) (73)
- Failure of physiological plasma glucose excursions to entrain high-frequency pulsatile insulin secretion in type 2 diabetes. (2000) (72)
- Alterations in pulsatile insulin secretion in the Zucker diabetic fatty rat. (1994) (70)
- Proinsulin radioimmunoassay in the evaluation of insulinomas and familial hyperproinsulinemia. (1986) (69)
- Hepatic metabolism of glucagon in the dog: contribution of the liver to overall metabolic disposal of glucagon. (1981) (69)
- Defective pancreatic beta-cell glycolytic signaling in hepatocyte nuclear factor-1alpha-deficient mice. (1998) (69)
- Diminished Insulin and Glucagon Secretory Responses to Arginine in Nondiabetic Subjects With a Mutation in the Hepatocyte Nuclear Factor–4α/MODY1 Gene (1997) (68)
- Hypoglycemic Thresholds for Cognitive Dysfunction in IDDM (1992) (68)
- Low Mitochondrial Glycerol Phosphate Dehydrogenase and Pyruvate Carboxylase in Pancreatic Islets of Zucker Diabetic Fatty Rats (1996) (67)
- Xenin-25 Potentiates Glucose-dependent Insulinotropic Polypeptide Action via a Novel Cholinergic Relay Mechanism* (2010) (67)
- Basal insulin hypersecretion in insulin-resistant Zucker diabetic and Zucker fatty rats: role of enhanced fuel metabolism. (1999) (67)
- Effects of weight loss and reduced hyperglycemia on the kinetics of insulin secretion in obese non-insulin dependent diabetes mellitus. (1990) (66)
- Calpain System Regulates Muscle Mass and Glucose Transporter GLUT4 Turnover* (2004) (66)
- Nocturnal elevation of glucose levels during fasting in noninsulin-dependent diabetes. (1991) (65)
- A Significant Role for Histocompatibility in Human Islet Transplantation (2006) (65)
- Plasma somatostatin 28 increases in response to feeding in man. (1983) (63)
- 24-hour glucose profiles during continuous or oscillatory insulin infusion. Demonstration of the functional significance of ultradian insulin oscillations. (1995) (62)
- Insulin release in impaired glucose tolerance: oral minimal model predicts normal sensitivity to glucose but defective response times. (2002) (62)
- Predominance of renal and absence of hepatic metabolism of pancreatic polypeptide in the dog. (1983) (61)
- Compensation in Pancreatic β-Cell Function in Subjects With Glucokinase Mutations (1994) (60)
- Alterations in the kinetics of C-peptide and insulin secretion in hyperthyroidism. (1993) (60)
- Abnormal temporal patterns of glucose tolerance in obesity: relationship to sleep-related growth hormone secretion and circadian cortisol rhythmicity. (1994) (59)
- CHAPTER 31 – Type 2 Diabetes Mellitus (2011) (59)
- Glyburide enhances the responsiveness of the beta-cell to glucose but does not correct the abnormal patterns of insulin secretion in noninsulin-dependent diabetes mellitus. (1989) (59)
- A 48-hour exposure of pancreatic islets to calpain inhibitors impairs mitochondrial fuel metabolism and the exocytosis of insulin. (2003) (59)
- Peripheral insulin parallels changes in insulin secretion more closely than C-peptide after bolus intravenous glucose administration. (1988) (59)
- Comprar Williams Textbook of Endocrinology 11th Ed | Kenneth S. Polonsky | 9781416029113 | Saunders (2007) (58)
- Suppressed Insulin Signaling and Increased Apoptosis in Cd38-Null Islets (2006) (56)
- Moderate Effect of Duodenal‐Jejunal Bypass Surgery on Glucose Homeostasis in Patients With Type 2 Diabetes (2012) (55)
- Glucagon-Like Peptide 1 Improves the Ability of the β-Cell to Sense and Respond to Glucose in Subjects With Impaired Glucose Tolerance (1998) (55)
- b-Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and (2014) (55)
- Changes in Pancreatic Islet Glucokinase and Hexokinase Activities With Increasing Age, Obesity, and the Onset of Diabetes (1997) (55)
- Xenin-25 Amplifies GIP-Mediated Insulin Secretion in Humans With Normal and Impaired Glucose Tolerance but Not Type 2 Diabetes (2012) (53)
- NIDDM is associated with loss of pancreatic beta-cell L-type Ca2+ channel activity. (1996) (52)
- Current approaches to measurement of insulin secretion. (1986) (52)
- Ingestion of a mixed meal does not affect the metabolic clearance rate of biosynthetic human C-peptide. (1986) (52)
- Maturity Onset Diabetes of the Young (MODY) (1989) (52)
- Insulin Secretory Profiles and C-Peptide Clearance Kinetics at 6 Months and 2 Years After Kidney-Pancreas Transplantation (1992) (50)
- Temporal Profiles and Clinical Significance of Pulsatile Insulin Secretion (1998) (49)
- Loss of Nix in Pdx1-deficient mice prevents apoptotic and necrotic β cell death and diabetes. (2010) (49)
- Lack of Glucagon Response to Hypoglycemia in Type I Diabetics After Long-Term Optimal Therapy with a Continuous Subcutaneous Insulin Infusion Pump (1983) (49)
- Retinol-binding protein 4, insulin resistance, and type 2 diabetes. (2006) (48)
- Rat inwardly rectifying potassium channel Kir6.2: cloning electrophysiological characterization, and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. (1996) (48)
- Glucose Counterregulation in Patients After Pancreatectomy: Comparison With Other Clinical Forms of Diabetes (1984) (48)
- Abnormalities of insulin pulsatility and glucose oscillations during meals in obese noninsulin-dependent diabetic patients: effects of weight reduction. (1996) (47)
- A novel point mutation in the human insulin gene giving rise to hyperproinsulinemia (proinsulin Kyoto). (1992) (47)
- The metabolic effects of biosynthetic human proinsulin in individuals with type I diabetes. (1984) (47)
- Lack of direct inhibition of insulin secretion by exogenous insulin in the canine pancreas. (1986) (46)
- Insulin secretory responses to rising and falling glucose concentrations are delayed in subjects with impaired glucose tolerance (2002) (46)
- Rosiglitazone reduces glucose-stimulated insulin secretion rate and increases insulin clearance in nondiabetic, insulin-resistant individuals. (2005) (46)
- Pattern of Postprandial Carbohydrate Metabolism and Effects of Portal and Peripheral Insulin Delivery (1990) (45)
- Basal and glucagon-stimulated plasma C-peptide concentrations in healthy dogs, dogs with diabetes mellitus, and dogs with hyperadrenocorticism. (1996) (45)
- Human insulin B24 (Phe----Ser). Secretion and metabolic clearance of the abnormal insulin in man and in a dog model. (1984) (45)
- Calculation of the systemic delivery rate of insulin in normal man. (1986) (45)
- Alterations in the ultradian oscillations of insulin secretion and plasma glucose in aging (1996) (43)
- A familial glucagonoma syndrome: genetic, clinical and biochemical features. (1981) (43)
- Hypoglycemic potency and metabolic clearance rate of intravenously administered human proinsulin and metabolites. (1990) (39)
- Evolution of beta-cell dysfunction in impaired glucose tolerance and diabetes. (2009) (39)
- International comparison of C-peptide measurements. (2007) (37)
- Effects of aging on glucose regulation during wakefulness and sleep. (1995) (37)
- Abnormalities in the ultradian oscillations of insulin secretion and glucose levels in Type 2 (non-insulin-dependent) diabetic patients (1992) (36)
- Adaptation to hyperglycemia enhances insulin secretion in glucokinase mutant mice. (1998) (35)
- Phase-locking regions in a forced model of slow insulin and glucose oscillations. (1995) (34)
- Hepatic and renal metabolism of somatostatin-like immunoreactivity. Simultaneous assessment in the dog. (1981) (34)
- Genetic Modulation of Lipid Profiles following Lifestyle Modification or Metformin Treatment: The Diabetes Prevention Program (2012) (33)
- Prevention of diabetes does not completely prevent insulin secretory defects in the ZDF rat. (1995) (33)
- Complex patterns of metabolic and Ca²⁺ entrainment in pancreatic islets by oscillatory glucose. (2013) (33)
- Diurnal variations in cardiovascular function and glucose regulation in normotensive humans. (1996) (32)
- Ca 2 + controls slow NAD ( P ) H oscillations in glucose-stimulated mouse pancreatic islets (2006) (32)
- Portal vein thrombosis complicating islet transplantation in a recipient with the Factor V Leiden mutation. (2004) (32)
- Reduced levels of messenger ribonucleic acid for calcium channel, glucose transporter-2, and glucokinase are associated with alterations in insulin secretion in fasted rats. (1994) (31)
- GLP-1-induced alterations in the glucose-stimulated insulin secretory dose-response curve. (2001) (30)
- Oscillatory Insulin Secretion After Pancreas Transplant (1993) (29)
- NATURAL HISTORY OF MULTIPLE INTRAHEPATIC CANINE ISLET ALLOGRAFTS DURING AND FOLLOWING ADMINISTRATION OF CYCLOSPORINE (1988) (29)
- Reevaluation of Urine C-Peptide as Measure of Insulin Secretion (1988) (27)
- Calpain-10 is a component of the obesity-related quantitative trait locus Adip1. (2010) (27)
- The Pancreatic β Cell Heats Up UCP2 and Insulin Secretion in Diabetes (2001) (27)
- The in vivo metabolism of somatostatin 28: possible relationship between diminished metabolism and enhanced biological action. (1982) (26)
- Preservation of insulin secretory responses to P2 purinoceptor agonists in Zucker diabetic fatty rats. (1996) (26)
- Impaired β-cell compensation to dexamethasone-induced hyperglycemia in women with polycystic ovary syndrome (2004) (25)
- Differential immunoreactivity of plasma glucagon components in man: studies with different glucagon antibodies. (1983) (25)
- Pancreatic hormone profiles and metabolism posthepatectomy in the dog. Evidence for a hepatotrophic role of insulin, glucagon, and pancreatic polypeptide. (1984) (25)
- Glucagon-like peptide 1 improves the ability of the beta-cell to sense and respond to glucose in subjects with impaired glucose tolerance. (1998) (24)
- Xenin-25 delays gastric emptying and reduces postprandial glucose levels in humans with and without type 2 diabetes. (2014) (24)
- Cloning of rat KATP-2 channel and decreased expression in pancreatic islets of male Zucker diabetic fatty rats. (1995) (24)
- Differential effects of glucose stimulation upon rapid pulses and ultradian oscillations of insulin secretion. (1993) (23)
- A novel point mutation in the insulin gene giving rise to hyperproinsulinemia. (1997) (22)
- Insulin and Glucagon Breakthrough of Somatostatin Suppression: Importance of Portal Vein Hormone Measurements (1981) (22)
- Insulin Signaling in α-cells Modulates Glucagon Secretion in vivo (2017) (22)
- The physician scientist training program in internal medicine at Washington University School of Medicine. (2009) (21)
- Oxygen uptake kinetics during exercise in diabetic neuropathy. (1988) (21)
- Evidence for the Presence of Somatostatin 28 in Plasma (1982) (21)
- Insulin secretion in insulin-resistant women with a history of gestational diabetes. (1995) (21)
- Insulin Wakayama: familial mutant insulin syndrome in Japan (1987) (21)
- Circulating forms of somatostatinlike immunoreactivity in human plasma. (1986) (20)
- To nap or not to nap? Residents' work hours revisited. (2009) (19)
- Impaired beta-cell compensation to dexamethasone-induced hyperglycemia in women with polycystic ovary syndrome. (2004) (19)
- Analytical problems in detecting rapid insulin secretory pulses in normal humans. (1993) (19)
- Effect of glyburide on beta cell responsiveness to glucose in non-insulin-dependent diabetes mellitus. (1990) (19)
- Hepatic Extraction of Plasma Immunoreactive Glucagon Components: Predilection for 3500-dalton Glucagon Metabolism by the Liver (1981) (18)
- Role of BH3-Only Molecules Bim and Puma in β-Cell Death in Pdx1 Deficiency (2014) (18)
- Heparin-induced lipolysis in hypertriglyceridemic subjects results in the formation of atypical HDL particles. (1994) (17)
- A new method for comparing portal and peripheral venous insulin delivery in humans: tolbutamide versus insulin infusion. (1994) (17)
- Alterations in the Patterns of Insulin Secretion Before and After Diagnosis of IDDM (1995) (17)
- Ginsenoside Re rapidly reverses insulin resistance in muscles of high-fat diet fed rats. (2012) (16)
- BH3-Only Molecule Bim Mediates β-Cell Death in IRS2 Deficiency (2014) (16)
- Pancreatic β-Cell Death due to Pdx-1 Deficiency Requires Multi-BH Domain Protein Bax but Not Bak* (2016) (15)
- Surface receptors for pancreatic hormones in dog and rat hepatocytes: qualitative and quantitative differences in hormone-target cell interactions. (1982) (15)
- Insulin acutely suppresses glucose production by both peripheral and hepatic effects in normal dogs. (1998) (15)
- Variation in the perilipin gene (PLIN) affects glucose and lipid metabolism in non-Hispanic white women with and without polycystic ovary syndrome. (2009) (14)
- Research in academic medical centers: Two threats to sustainable support (2015) (14)
- Serum Leptin Levels in Obese Males During Over‐ and Underfeeding (2009) (14)
- The Metabolic Clearance Rate of Glucagon (1983) (13)
- Inhibition of calpain results in impaired contraction-stimulated GLUT4 translocation in skeletal muscle. (2006) (13)
- Persistence of oscillatory insulin secretion in denervated islet cell autografts. (1991) (12)
- The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes. (2001) (12)
- Gastric banding to treat obesity: band-aid or breakthrough? (2008) (12)
- Evidence that insulin can directly inhibit hepatic glucose production (1997) (12)
- 35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
- Diabetic pancreatic β cells ARNT all they should be (2005) (11)
- Quantitative evaluation of the effect of low-intensity exercise on insulin secretion in man. (1993) (11)
- 35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts. (1999) (11)
- The effect of biosynthetic human proinsulin on the hepatic response to glucagon in insulin-deficient diabetes. (1987) (11)
- Postprandial triglyceride response in Type 1 (insulin-dependent) diabetes mellitus is not altered by short-term deterioration in glycaemic control or level of postprandial insulin replacement (1991) (10)
- Lack of effect of high-dose biosynthetic human C-peptide on pancreatic hormone release in normal subjects. (1990) (8)
- Sustained expression of hepatocyte nuclear factor-6 leads to loss of pancreatic beta-cells by apoptosis. (2007) (7)
- Role of HNF-1alpha in regulating the expression of genes involved in cellular growth and proliferation in pancreatic beta-cells. (2009) (6)
- Diabetic pancreatic beta cells ARNT all they should be. (2005) (6)
- Late post-prandial hypoglycaemia as the sole presenting feature of secreting pancreatic beta-cell adenoma in a subtotally gastrectomized patient. (1997) (6)
- CHAPTER 1 – Principles of Endocrinology (2011) (6)
- Glucagon-like peptide-1 stimulates insulin secretion by a Ca2+-independent mechanism in Zucker diabetic fatty rat islets of Langerhans. (2000) (6)
- Diagnosis of acromegaly in a patient with type 1 diabetes mellitus. (2002) (5)
- Natural History, Genetics and Pathogenesis of HNF-4α/MODY1 (2000) (5)
- Glucagon does not increase plasma free fatty acid and glycerol concentrations in patients with noninsulin-dependent diabetes mellitus. (1993) (5)
- Aspects of Oscillatory Insulin Secretion (1991) (5)
- Impaired insulin secretion in transgenic mice over-expressing calpastatin in pancreatic β-cells (2009) (5)
- Calpain-10 is a component of the obesity-related quantitative trait locus Adip1 (2010) (4)
- A practical approach to fasting hypoglycemia. (1992) (4)
- The effect of a time delay on the characteristics of the canine glucoregulatory system. (1990) (4)
- Alternative insulin delivery systems: how demanding should the patient be? (1997) (4)
- Xenin-25 Ampli fi es GIP-Mediated Insulin Secretion in Humans With Normal and Impaired Glucose Tolerance but Not Type 2 Diabetes (2012) (4)
- Insulin acutely suppresses glucose production by both peripheral and hepatic effects in normal dogs. (1998) (4)
- The 2018 World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) score and diabetes risk in the Diabetes Prevention Program Outcomes Study (DPPOS) (2022) (3)
- Mutant insulin syndrome: identification of two families with [LeuA3]insulin and determination of its biological activity. (1986) (3)
- Beta-Cell Function in Polycystic Ovary Syndrome (1996) (3)
- The measurement and validation of the nonsteady-state rates of C-peptide appearance in the dog (1986) (3)
- Insulin production: from gene to granule (1997) (3)
- Does Tight Glucose Control Enhance Brain Sensitivity to Low Glucose? (1991) (2)
- 1 BH 3-only molecule Bim mediates β-cell death in IRS 2 deficiency (2014) (2)
- Donald F. Steiner, MD, 1930–2014 (2015) (2)
- Production of small HDL particles after intravenous heparin in hypertriglyceridemic (HTG) diabetic and non-diabetic individuals. Studies before and after gemfibrozil therapy (1994) (2)
- Genetic Testing in Diabetes Mellitus (2010) (2)
- XENIN-25 POTENTIATES GIP ACTION VIA A NOVEL CHOLINERGIC RELAY MECHANISM (2010) (2)
- Donald F. Steiner MD, 1930–2014: Discoverer of proinsulin (2015) (2)
- Insulin production: from gene to granule (1997) (1)
- Organ alchemy: producing insulin in the liver (2003) (1)
- Significance of HLA in human islet transplantation (2004) (1)
- The Kinetics of Insulin, C-Peptide, and Proinsulin in Normal and Diabetic Man (1989) (1)
- Oscillatory Insulin Secretion (1994) (1)
- Response letter to comment on: Villareal et al. (2009) TCF7L2 Variant rs7903146 Affects the Risk of Type 2 Diabetes by Modulating Incretin Action. Diabetes; 59:479–485 (2010) (1)
- Effects of insulin mediated plasma glucose changes on brain function. Implications from experimental and derived data. (1991) (1)
- Glucagon and Renal Insufficiency (1983) (1)
- Irish endocrine society (1993) (1)
- TROGLITAZONE IMPROVES DEFECTS IN INSULIN ACTION, INSULIN SECRETION, OVARIAN STEROIDOGENESIS, AND FIBRINOLYSIS IN WOMEN WITH POLYCYSTIC OVARY SYNDROME (1998) (0)
- The University of Chicago and the Work of Mark Siegler in Clinical Medical Ethics (2017) (0)
- Introduction of Arthur H. Rubenstein. (2012) (0)
- The Washington University Institute for Clinical and Translational Sciences (2009) (0)
- two-channel high-density microarray experiments Comparison of different labeling methods for (2015) (0)
- from a two-compartment model Undermodeling affects minimal model indexes: insights (2011) (0)
- Beta-cell function from bench to bedside (2001) (0)
- Reduced (cid:1) -cell mass and altered glucose sensing impair insulin-secretory function in (cid:1) IRKO mice (2003) (0)
- Irish endocrine society (1994) (0)
- Nesidioblastosis is Not a Histopathologic Diagnosis. 380 (1997) (0)
- Responses of somatostatin components to oral glucose in human plasma. (1983) (0)
- Beta-cell dysfunction in prediabetic and diabetic MODY subjects (2001) (0)
- IER3IP1 Regulates Beta-Cell Survival (2018) (0)
- (cid:2) -Cell Failure in Type 2 Diabetes: Postulated Mechanisms and Prospects for Prevention and Treatment (2014) (0)
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What Schools Are Affiliated With Kenneth S. Polonsky?
Kenneth S. Polonsky is affiliated with the following schools:
