Kenneth J. Siddle

Kenneth J. Siddle's AcademicInfluence.com Rankings

Kenneth J. Siddle

Biology

#13515

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#17063

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Biochemistry

#2370

World Rank

#2520

Historical Rank

biology Degrees

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Biology

Kenneth J. Siddle's Degrees

PhD Biochemistry University of California, San Francisco

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Kenneth J. Siddle's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. (1998) (939)
Signalling by insulin and IGF receptors: supporting acts and new players. (2011) (399)
Sensitive and specific two-site immunoradiometric assays for human insulin, proinsulin, 65-66 split and 32-33 split proinsulins. (1989) (352)
Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity. (1987) (300)
Purified hybrid insulin/insulin-like growth factor-I receptors bind insulin-like growth factor-I, but not insulin, with high affinity. (1993) (275)
Insulin receptor/IGF-I receptor hybrids are widely distributed in mammalian tissues: quantification of individual receptor species by selective immunoprecipitation and immunoblotting. (1997) (270)
Insulin and insulin-like growth factor-I (IGF-I) receptor overexpression in breast cancers leads to insulin/IGF-I hybrid receptor overexpression: evidence for a second mechanism of IGF-I signaling. (1999) (265)
Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase. (1995) (257)
Tumor Necrosis Factor-α Induces Apoptosis of Human Adipose Cells (1997) (222)
Receptors for insulin and insulin-like growth factor-I can form hybrid dimers. Characterisation of hybrid receptors in transfected cells. (1990) (193)
Characterization of insulin/IGF hybrid receptors: contributions of the insulin receptor L2 and Fn1 domains and the alternatively spliced exon 11 sequence to ligand binding and receptor activation. (2007) (189)
Immunological relationships between receptors for insulin and insulin-like growth factor I. Evidence for structural heterogeneity of insulin-like growth factor I receptors involving hybrids with insulin receptors. (1989) (182)
Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors. (2001) (165)
Grb10 and Grb14: enigmatic regulators of insulin action--and more? (2005) (162)
Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor. (1986) (156)
Tumor necrosis factor-alpha induces apoptosis of human adipose cells. (1997) (136)
A HIGH SENSITIVITY IMMUNOCHEMILUMINOMETRIC ASSAY FOR HUMAN THYROTROPHIN (1984) (131)
Compartment-specific regulation of phosphoinositide 3-kinase by platelet-derived growth factor and insulin in 3T3-L1 adipocytes. (1996) (130)
Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes (2012) (129)
Human Preadipocytes Display a Depot-Specific Susceptibility to Apoptosis (1998) (127)
Insulin receptor kinase domain autophosphorylation regulates receptor enzymatic function. (1992) (127)
Cell proliferation activities on skin fibroblasts from a short child with absence of one copy of the type 1 insulin-like growth factor receptor (IGF1R) gene and a tall child with three copies of the IGF1R gene. (2003) (126)
Molecular Basis of Signaling Specificity of Insulin and IGF Receptors: Neglected Corners and Recent Advances (2011) (124)
A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity. (1992) (118)
Defect in Insulin-Like Growth Factor-1 Survival Mechanism in Atherosclerotic Plaque-Derived Vascular Smooth Muscle Cells Is Mediated by Reduced Surface Binding and Signaling (2001) (115)
Signaling-competent receptor chimeras allow mapping of major insulin receptor binding domain determinants. (1993) (108)
Hormonal control of adipose tissue lipolysis (1975) (107)
The role of insulin receptor kinase domain autophosphorylation in receptor-mediated activities. Analysis with insulin and anti-receptor antibodies. (1992) (105)
The involvement of microRNAs in Type 2 diabetes. (2010) (96)
Two Naturally Occurring Insulin Receptor Tyrosine Kinase Domain Mutants Provide Evidence That Phosphoinositide 3-Kinase Activation Alone Is Not Sufficient for the Mediation of Insulin’s Metabolic and Mitogenic Effects* (1997) (93)
The insulin receptor tyrosyl kinase phosphorylates holomeric forms of the guanine nucleotide regulatory proteins Gi and Go (1987) (92)
Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors. (1991) (87)
The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation (2009) (79)
Involvement of phosphoinositide 3-kinase in insulin stimulation of MAP-kinase and phosphorylation of protein kinase-B in human skeletal muscle: implications for glucose metabolism (1997) (78)
Mutational analysis of insulin receptor function: consensus and controversy. (1993) (78)
New separation method for monoclonal immunoradiometric assays and its application to assays for thyrotropin and human choriogonadotropin. (1984) (71)
The insulin receptor functions normally in Chinese hamster ovary cells after truncation of the C terminus. (1991) (70)
Testicular cancer secretes intact human choriogonadotropin (hCG) and its free beta-subunit: evidence that hCG (+hCG-beta) assays are the most reliable in diagnosis and follow-up. (1990) (69)
Differential Regulation of Phosphoinositide 3-Kinase Adapter Subunit Variants by Insulin in Human Skeletal Muscle* (1997) (68)
Chloroquine Extends the Lifetime of the Activated Insulin Receptor Complex in Endosomes* (1997) (68)
Microarray Analysis of Insulin and Insulin-like Growth Factor-1 (IGF-1) Receptor Signaling Reveals the Selective Up-regulation of the Mitogen Heparin-binding EGF-like Growth Factor by IGF-1* (2002) (68)
Inhibitors of phosphoinositide 3-kinase block exocytosis but not endocytosis of transferrin receptors in 3T3-L1 adipocytes. (1995) (68)
c phosphorylation and activation of the IGF-I receptor in src-transformed cells. (1994) (65)
Identification of epitopes on the human insulin receptor reacting with rabbit polyclonal antisera and mouse monoclonal antibodies. (1990) (62)
Analysis of insulin-receptor phosphorylation sites in intact cells by two-dimensional phosphopeptide mapping. (1988) (62)
Differences in Signaling Properties of the Cytoplasmic Domains of the Insulin Receptor and Insulin-like Growth Factor Receptor in 3T3-L1 Adipocytes* (1999) (62)
Monoclonal antibodies to the insulin receptor mimic metabolic effects of insulin but do not stimulate receptor autophosphorylation in transfected NIH 3T3 fibroblasts. (1989) (60)
Phosphoinositide 3-kinase: the key switch in insulin signalling (1998) (60)
Actions of insulin and insulinlike growth factors I and II in cultured microvessel endothelial cells from bovine adipose tissue. (1988) (59)
Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation. (2006) (57)
Internalization of the human insulin receptor. The insulin-independent pathway. (1992) (56)
Hybrid and atypical insulin/insulin-like growth factor I receptors. (1994) (55)
Insulin-like and insulin-inhibitory effects of monoclonal antibodies for different epitopes on the human insulin receptor. (1987) (55)
Peptide Hormone Action: A Practical Approach (1991) (54)
IGF-I inhibits apoptosis induced by serum withdrawal, but potentiates TNF-alpha-induced apoptosis, in 3T3-L1 preadipocytes. (2000) (54)
Solubilization and purification of rat liver 5'-nucleotidase by use of a zwitterionic detergent and a monoclonal-antibody immunoadsorbent. (1982) (51)
Characterization of monoclonal antibodies directed against human thyroid stimulating hormone. (1982) (50)
The human insulin receptor mRNA contains a functional internal ribosome entry segment (2009) (50)
Immunoaffinity purification of intact, metabolically active, cholinergic nerve terminals from mammalian brain. (1984) (45)
Monoclonal antibodies to the insulin receptor stimulate the intrinsic tyrosine kinase activity by cross‐linking receptor molecules. (1987) (45)
A monoclonal anti-peptide antibody reacting with the insulin receptor beta-subunit. Characterization of the antibody and its epitope and use in immunoaffinity purification of intact receptors. (1992) (44)
Evidence for free beta‐subunit secretion in so‐called human chorionic gonadotropin‐positive seminoma (1988) (43)
The relationship between the concentration of adenosine 3':5'-cyclic monophosphate and the anti-lipolytic action of insulin in isolated rat fat-cells. (1974) (43)
The action of local anaesthetics on lipolysis and on adenosine 3':5'-cyclic monophosphate content in isolated rat fat-cells. (1974) (43)
Deletion analysis of the human insulin receptor ectodomain reveals independently folded soluble subdomains and insulin binding by a monomeric alpha-subunit. (1990) (42)
Insulin-like growth factors in human breast cancer (2004) (40)
Two-site monoclonal antibody assays for human heart- and brain-type creatine kinase. (1984) (39)
Molecular scanning of the insulin receptor substrate 1 gene in subjects with severe insulin resistance: detection and functional analysis of a naturally occurring mutation in a YMXM motif. (1998) (39)
Differential Signaling to Glycogen Synthesis by the Intracellular Domain of the Insulin versus the Insulin-like Growth Factor-1 Receptor (1997) (38)
Single-molecule imaging of human insulin receptor ectodomain and its Fab complexes. (1999) (38)
Role of Insulin Receptor Dimerization Domains in Ligand Binding, Cooperativity, and Modulation by Anti-receptor Antibodies* (2002) (37)
Production and characterization of monoclonal antibodies to insulin secretory granule membranes. (1987) (36)
The preparation of monoclonal antibodies to human bone and liver alkaline phosphatase and their use in immunoaffinity purification and in studying these enzymes when present in serum. (1987) (35)
An Investigation of the Ligand Binding Properties and Negative Cooperativity of Soluble Insulin-like Growth Factor Receptors* (2008) (35)
Cytoplasmic juxtamembrane region of the insulin receptor: a critical role in ATP binding, endogenous substrate phosphorylation, and insulin-stimulated bioeffects in CHO cells. (1991) (34)
The effect of intracellular calcium ions on adrenaline-stimulated adenosine 3':5'-cyclic monophosphate concentrations in pigeon erythrocytes, studied by using the ionophore A23187. (1976) (34)
The existence and properties of two dimers of rat liver ecto-5'-nucleotidase. (1984) (34)
Peptide hormone secretion : a practical approach (1990) (34)
Site-specific anti-phosphopeptide antibodies: use in assessing insulin receptor serine/threonine phosphorylation state and identification of serine-1327 as a novel site of phorbol ester-induced phosphorylation. (1994) (33)
The insulin receptor and type I IGF receptor: comparison of structure and function. (1992) (33)
Biosynthesis of insulin secretory granule membrane proteins. Control by glucose. (1987) (33)
The insulin receptor: from protein sequence to structure. (1999) (33)
A rapid, sensitive two-site immunometric assay for TSH using monoclonal antibodies: investigation of factors affecting optimisation. (1984) (33)
Phorbol esters stimulate phosphatidylinositol 3,4,5-trisphosphate production in 3T3-L1 adipocytes: implications for stimulation of glucose transport. (1996) (32)
A third fibronectin type III domain in the extracellular region of the insulin receptor family (1998) (31)
Immunoaffinity purification of human complement component C9 using monoclonal antibodies. (1983) (31)
Immunolocalization of complement component C9 on necrotic and non-necrotic muscle fibres in myositis using monoclonal antibodies: a primary role of complement in autoimmune cell damage. (1984) (30)
The effects of glucagon and insulin on adenosine 3':5'-cyclic monophosphate concentrations in an organ culture of mature rat liver. (1973) (30)
Characterization and Use in Immunoradiometric Assay of Monoclonal Antibodies Directed Against Human Proinsulin (1987) (30)
PROINSULIN IN HUMAN SERUM: PROBLEMS IN MEASUREMENT AND INTERPRETATION (1984) (30)
The distinction of bone and liver isoenzymes of alkaline phosphatase in serum using a monoclonal antibody. (1988) (30)
Multisite serine phosphorylation of the insulin and IGF‐I receptors in transfected cells (1991) (29)
A method for the determination of glucose-6-phosphatase activity in rat liver with [U-14C]glucose 6-phosphate as substrate. (1978) (28)
Red cell-labelled monoclonal antibodies for assay of human chorionic gonadotropin and luteinising hormone by reverse passive haemagglutination. (1984) (28)
Two Isoforms of the mRNA Binding Protein IGF2BP2 Are Generated by Alternative Translational Initiation (2012) (27)
Interaction of the human insulin receptor with the ras oncogene product p21 (1987) (26)
The α‐isoform of class II phosphoinositide 3‐kinase is more effectively activated by insulin receptors than IGF receptors, and activation requires receptor NPEY motifs (1999) (25)
Functional activation of mutant human insulin receptor by monoclonal antibody (1996) (25)
Structural domains of the insulin receptor and IGF receptor required for dimerisation and ligand binding (2000) (25)
A monoclonal antibody inhibiting rat liver 5′‐nucleotidase (1981) (24)
Comparison of anti-apoptotic signalling by the insulin receptor and IGF-I receptor in preadipocytes and adipocytes. (2001) (24)
A Kex2-related endopeptidase activity present in rat liver specifically processes the insulin proreceptor. (1994) (23)
Immunological studies of type I IGF receptors and insulin receptors: characterisation of hybrid and atypical receptor subtypes. (1993) (23)
Dissociation of the effect of adrenalin on glucose uptake from that on adenosine cyclic 3',5'-monophosphate levels and on lipolysis in rat-isolated fat cells. (1974) (22)
Insulin and IGF‐1 receptors contain covalently bound palmitic acid (1988) (21)
Adipose depot-specific expression of cIAP2 in human preadipocytes and modulation of expression by serum factors and TNFα (2001) (21)
Characterisation of monoclonal antibodies for human luteinising hormone, and mapping of antigenic determinants on the hormone. (1983) (21)
Investigation of the subcellular distribution of cyclic-AMP phosphodiesterase in rat hepatocytes, using a rapid immunological procedure for the isolation of plasma membrane. (1979) (21)
Effect of hormones on content of purine nucleoside cyclic monophosphates in perfused rat liver (1978) (20)
The Properties, Structure, Function, Intracellular Localisation and Movement of Hepatic 5′-Nucleotidase (1986) (20)
Monoclonal antibodies as probes of the structure and function of insulin receptors. (1987) (20)
Mechanism of insulin receptor kinase inhibition in non-insulin-dependent diabetes mellitus patients. Phosphorylation of serine 1327 or threonine 1348 is unaltered. (1995) (20)
Molecular basis of insulin receptor function. (1989) (20)
Changes in insulin-receptor structure associated with trypsin-induced activation of the receptor tyrosine kinase. (1991) (20)
Insulin-like growth factor (IGF)-I A- and B-domain analogues with altered type 1 IGF and insulin receptor binding specificities. (1996) (19)
Anti-(insulin receptor) monoclonal antibody-stimulated tyrosine phosphorylation in cells transfected with human insulin receptor cDNA. (1990) (19)
Is stimulation of class-1 phosphatidylinositol 3-kinase activity by insulin sufficient to activate pathways involved in glucose metabolism. (1997) (19)
The effect of insulin on adenosine 3':5'-monophosphate and guanosine 3':5'-monophosphate concentrations in human plasma. (1976) (18)
Glycomics investigation into insulin action. (2006) (18)
Hybrid Insulin Receptors: Molecular Mechanisms of Negative-Dominant Mutations in Receptor-Mediated Insulin Resistance (1990) (18)
A monoclonal antibody to human brain-type creatine kinase. Increased avidity with mercaptans. (1983) (17)
Muscle-Specific Expression of Human Insulin Receptor in Transgenic Mice (1993) (17)
Immunoradiometric assay for human complement component C9 utilising monoclonal antibodies. (1983) (16)
Phorbol esters induce insulin receptor phosphorylation in transfected fibroblasts without affecting tyrosine kinase activity. (1993) (16)
Control of renal tubular phosphate reabsorption by parathyroid hormone in man. (1977) (16)
Localisation of 5'-nucleotidase in a rat liver cell line using a monoclonal antibody and indirect immunofluorescent labelling. (1983) (16)
Plasma adenosine 3':5'-cyclic monophosphate response to glucagon in thyroid disease. (1975) (15)
Radiation doses to the lens of the eye during computerised tomography of the orbit; a comparison of four modern computerised tomography units. (1990) (15)
Phorbol ester-induced downregulation of protein kinase C potentiates insulin receptor tyrosine autophosphorylation: evidence for a major constitutive role in insulin receptor regulation. (1990) (14)
Attractin' more attention - new pieces in the obesity puzzle? (2003) (14)
Acute knockdown of the insulin receptor or its substrates Irs1 and 2 in 3T3-L1 adipocytes suppresses adiponectin production (2016) (14)
Deletion of V335 from the L2 domain of the insulin receptor results in a conformationally abnormal receptor that is unable to bind insulin and causes Donohue's syndrome in a human subject. (2003) (14)
Insulin activates glycogen synthase by a novel PI 3-kinase/p70s6k dependent pathway in 3T3-L1 adipocytes. (1995) (13)
Guanine nucleotide regulatory proteins in insulin's action and in diabetes. (1989) (12)
Diaphyseal Paget's disease: an unusual finding in the tibia. (1984) (11)
Methods for the measurement of insulin secretion (1990) (11)
Cell-autonomous programming of rat adipose tissue insulin signalling proteins by maternal nutrition (2016) (10)
The role of insulin dissociation from its endosomal receptor in insulin degradation (2000) (10)
An enzyme-amplified monoclonal immunoenzymometric assay for prostatic acid phosphatase. (1985) (10)
Binding to GDP-agarose identifies a novel 60kDa substrate for the insulin receptor tyrosyl kinase in mouse NIH-3T3 cells expressing high concentrations of the human insulin receptor. (1989) (10)
Calcium as a Mediator of Hormone Action (1977) (10)
Possible mechanisms for the increased sensitivity to glucagon and catecholamines of chicken adipose tissue during hatching. (1979) (9)
C-terminus or juxtamembrane deletions in the insulin receptor do not affect the glucose-dependent inhibition of the tyrosine kinase activity. (1995) (9)
The effect of bivalent cation chelating agents on some actions of adrenalin and insulin in rat isolated fat cells. (1980) (9)
Differential phosphorylation of IRS-1 and IRS-2 by insulin and IGF-I receptors (2006) (8)
The effect of 5-hydroxytryptamine and other indole derivatives on the formation of adenosine 3',5'-cyclic monophosphate in pigeon erythrocytes. (1977) (8)
The carboxyl‐terminal domain of insulin‐like growth factor‐I receptor interacts with the insulin receptor and activates its protein tyrosine kinase (1998) (8)
Radiation dose to the lens of the eye during computerised tomography examinations of the orbit, the pituitary fossa and the brain on a General Electric 9800 Quick C.T. scanner. (1990) (7)
Magnetic resonance imaging evaluation: preliminary utilization and application report (1988) (7)
Clinical assays of products of normal and malignant cells. (1984) (7)
After-hours radiology. (1994) (7)
Rat and Mouse Monoclonal Antibodies to Human Myelin Basic Protein (1986) (7)
Immunoaffinity purification of insulin receptor by use of monclonal antibodies (1986) (6)
Hormonal control of adipose tissue lipolysis. (1975) (6)
The purified COOH-terminal domain of the insulin receptor carries activity to stimulate protein kinase activity or autophosphorylation of the beta subunit domain of insulin receptor. (1994) (6)
Human insulin receptor contains covalently bound palmitic acid (1986) (6)
The effect of local anaesthetics on lipolysis in fat-cells. (1972) (6)
Involvement of PI 3-kinase in stimulation of glucose transport and recruitment of transferrin receptors in 3T3-L1 adipocytes. (1995) (6)
Calcium as a mediator of hormone action [proceedings]. (1977) (5)
Evaluation of anti-insulin receptor antibodies as potential novel therapies for human insulin receptoropathy using cell culture models (2017) (5)
Calcium and lipolysis in adipose tissue: effects of ethanedioxybis-(ethylamine)tetra-acetate (EGTA) and ionophore A23187 [proceedings]. (1977) (5)
The importance of measuring intracellular free Ca2+. (1979) (5)
Developmental Origins of Insulin Resistance and Type 2 Diabetes (2011) (5)
Persistent Aphasia following a purely subcortical lesion: A magnetic resonance imaging study (1991) (5)
Evaluation of pre-operative chest x-ray. (1987) (5)
Anti-Insulin Receptor Antibodies Improve Hyperglycemia in a Mouse Model of Human Insulin Receptoropathy (2020) (4)
Detection of ecto-5'-nucleotidase on rat B and T lymphocyte subpopulations using a monoclonal antibody in rosetting reactions. (1987) (4)
Corrosion of lead shielding in a radiology department. (1999) (4)
Alternative IGF-Related Receptors (1999) (4)
Effect of phorbol esters on phosphatidylinositol 3-kinase activity in adipocytes. (1995) (4)
The action of pancreatic hormones on the cyclic AMP content of isolated chicken hepatocytes. (1979) (4)
Insulin-stimulated serine/threonine phosphorylation of the insulin receptor: paucity of threonine 1348 phosphorylation in vitro indicates the involvement of more than one serine/threonine kinase in vivo. (1991) (3)
The Insulin Receptor and Downstream Signalling (2005) (3)
Effect of replacement of extracellular sodium ions and of D-600 on the activation by adrenalin of adenylate cyclase in intact pigeon erythrocytes (1978) (3)
The role of phosphatidylinositol 3-kinase activity in insulin-stimulated mitogenesis in 3T3-L1 adipocytes. (1995) (3)
Calcium ions and adenosine 3':5'-cyclic monophosphate in hepatocytes: effects of ethanedioxybis(ethylamine)tetra-acetate (EGTA) and ionophore A23187 [proceedings]. (1979) (3)
The insulin secretory granule: features and functions in common with other endocrine granules. (1986) (3)
Free β-subunit secretion of hCG in patients with trophoblastic diseases (1987) (3)
Immunological Isolation of Hepatocyte Plasma Membranes (1978) (2)
Insulin binding and action in a human liver cell line (1985) (2)
The production of monoclonal antibodies to rat liver plasma membranes. (1981) (2)
Monoclonal antibodies for the human insulin receptor stimulate intrinsic receptor-kinase activity (1986) (2)
Monoclonal antibodies against human alkaline phosphatases (1985) (2)
Approaches to Isolating Minor Membrane Components Using Monoclonal Antibodies, as in Purifying 5′-Nucleotidase (1984) (1)
MRI as an Aid to the Differential Diagnosis of Dysarthria of Supra-Nuclear Origin (1990) (1)
[Biogenesis of the insulin secretion granule]. (1989) (1)
Turnover of insulin receptors in cells transfected with human insulin receptor cDNA (1989) (1)
The Use of a Zwitterionic Detergent and a Monoclonal Antibody in Purification of Rat Liver 5'-Nucleotidase (1982) (1)
Insulin-inhibitory and insulin-like effects of monoclonal antibodies for the human insulin receptor (1986) (1)
Insulin and Insulin-like Growth Factor-I ( IGF-I ) Receptor Overexpression in Breast Cancers Leads to Insulin / IGF-I Hybrid Receptor Overexpression : Evidence for a Second Mechanism of IGF-I Signaling 1 (1999) (1)
Monoclonal antibodies against creatine kinase isoenzymes (1985) (1)
Immunohistochemical and serological differentiation of hCG-like activity in seminoma (1988) (0)
New SeparationMethodfor MonoclonalImmunoradiometricAssaysand Its Applicationto Assaysfor Thyrotropinand HumanChoriogonadotropin (2004) (0)
P-69: Stable expression of signalling proteins in 3T3-L1 adipocytes (2009) (0)
European endocrine answer (1978) (0)
Molecular Aspects of Hormone Regulation (2021) (0)
The development of radioimmunoassay: cover version proves a big hit and outsells the original (2006) (0)
Adipose cell apoptosis is regulated by tumor necrosis factor-alpha and insulin-like growth factor 1 (1997) (0)
Monoclonal antibodies for the human insulin receptor (1985) (0)
Diagnostic value of the free β-subunit of human chorionic gonadotropin (hCG) in seminoma and gestational trophoblastic diseases (1987) (0)
Impact of metformin on gene expression, glucose uptake and lipolysis in adipocytes (2008) (0)
Correction to ‘The human insulin receptor mRNA contains a functional internal ribosome entry segment’ (2022) (0)
HCG and the free β-subunit exist in the human pituitary (1988) (0)
The effect of glucagon on adenosine 3':5'-cyclic monophosphate concentrations in an organ culture of adult rat liver. (1972) (0)
Molecular cloning and bacterial expression of a peptide with immunological similarity to the insulin receptor (1986) (0)
Sixteenth annual symposium on advanced analytical concepts for the clinical laboratory. (1984) (0)
The imprinted Mir483 is a growth suppressor and metabolic regulator functioning through IGF1 (2022) (0)
P-40: Insulin stimulation of PI 3-kinase and MAP kinase and roles of these in glucose metabolism in human skeletal muscle (2009) (0)
USE OF POLYCLONAL AND MONOCLONAL ANTIBODIES IN STUDYING COMPLEMENT COMPONENT C9 AS A TRANS-MEMBRANE PROTEIN (1985) (0)
Analysis of the sites of phosphorylation of the insulin receptor in vitro and in vivo (1988) (0)
The virgin and child, three saints and a donor. A case report. (1984) (0)
Chronic Aphasia Following a Left Striato-Capsular Infarct - An Mri Study (1991) (0)
Nick Hales: an appreciation of his life and work (2006) (0)
O-29: Identical substrate specificity of insulin and IGF-1 receptor tyrosine kinases in phosphorylation of insulin receptor substrate-1 (2009) (0)
Monoclonal Antibodies to the Insulin Receptor (1988) (0)
SOLUBILIZATION AND PURIFICATION OF THE INTRINSIC MEMBRANE PROTEIN 5′-NUCLEOTIDASE USING ZWITTERIONIC DETERGENT AND MONOCLONAL ANTIBODY (1981) (0)
PRODUCTION OF MONOCLONAL ANTIBODIES TO RAT LIVER MEMBRANE ANTIGENS (1981) (0)
O-9: Characterisation of hybrid receptors in human fibroblasts (2009) (0)
Immunological isolation of hepatocyte plasma membranes [proceedings]. (1978) (0)
Charles Nicholas Hales. 25 April 1935 — 15 September 2005 (2010) (0)
P-15: The relationship between atypical IGF-1 receptors and classical receptors (2009) (0)
Thyrotropin Concentrations in Normal and Hyperthyroid Subjects (1984) (0)
Specificity in ligand binding and intracellular signalling by insulin and IGF receptors (2001) (0)
Characterization of tumor hCG variants by immunoblotting in serum and urine of patients with testicular cancer (1988) (0)
Book reviewsMethods of hybridoma formation: Edited by A.H. Bartal and Y. Hirshaut humana press, 1987 (distributed by Wiley, Chichester, UK) hardback, 504 pp., £65.80 (1989) (0)
P-30: The carboxyl terminal 110 amino acids of insulin-like growth factor-I receptor interact with the insulin receptor and activates its tyrosine protein kinase (2009) (0)
Proceedings: Plasma cyclic AMP response to glucagon in thyroid disease. (1974) (0)
Insulin action and receptor phosphorylation in cell lines transfected with insulin receptor cDNA (1989) (0)
Eighth annual meeting of the European Association for the Study of Diabetes (1973) (0)
Lack of effect of insulin on guanosine 3':5'-cyclic monophosphate content of insulin-sensitive rat hepatocytes [proceedings]. (1979) (0)
The insulin receptor tyrosyl kinase fails to phosphorylate the guanine nucleotide regulatory proteins Ni, No and p21 (1986) (0)
P-32: TrkC/insulin receptor and TrkC/IGF-1 receptor chimaeras: Tools for the examination of differential signalling to mitogenic and metabolic events by the intracellular domains of the insulin and IGF-1 receptors (2009) (0)
O-44: Regulation of phosphoinositide 3-kinase by PDGF and insulin in 3T3-L1 adipocytes (2009) (0)
NewSeparation Method forMonoclonal Immunoradiometric AssaysandIts Application toAssaysforThyrotropin andHumanChoriogonadotropin (1984) (0)
P-18: Increased insulin affinity of the IGF-I receptor requires a nonpolar aromatic amino acid at position #32 (2009) (0)
Erratum: Differential signaling to glycogen synthesis by the intracellular domain of the insulin versus the insulin-like growth factor-1 receptor. Evidence from studies of TrkC-chimeras (Journal of Biological Chemistry (1997) 272 (24325-24332)) (1997) (0)

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What Schools Are Affiliated With Kenneth J. Siddle?

Kenneth J. Siddle is affiliated with the following schools:

University of Iowa
University of Cambridge