Ka Yiu San
#98,561
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American bioengineer
Ka Yiu San's AcademicInfluence.com Rankings
Ka Yiu Sanengineering Degrees
Engineering
#3433
World Rank
#4511
Historical Rank
Bioengineering
#43
World Rank
#45
Historical Rank
Biomedical Engineering
#817
World Rank
#829
Historical Rank
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Engineering
Ka Yiu San's Degrees
- Bachelors Biomedical Engineering Stanford University
Why Is Ka Yiu San Influential?
(Suggest an Edit or Addition)According to Wikipedia, Ka Yiu San is an American bioengineer currently on the faculty at Rice University and an Elected Fellow of the American Association for the Advancement of Science. Education In 1978, San earned a BS degree from Rice University. San earned a MS and PhD degrees from the California Institute of Technology.
Ka Yiu San's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Studies on on‐line bioreactor identification. I. Theory (1984) (263)
- Metabolic engineering through cofactor manipulation and its effects on metabolic flux redistribution in Escherichia coli. (2002) (261)
- Metabolic engineering of Escherichia coli: increase of NADH availability by overexpressing an NAD(+)-dependent formate dehydrogenase. (2002) (258)
- Novel pathway engineering design of the anaerobic central metabolic pathway in Escherichia coli to increase succinate yield and productivity. (2005) (253)
- Metabolic engineering of aerobic succinate production systems in Escherichia coli to improve process productivity and achieve the maximum theoretical succinate yield. (2005) (195)
- Succinate production in Escherichia coli (2012) (166)
- Transcriptional response of the terpenoid indole alkaloid pathway to the overexpression of ORCA3 along with jasmonic acid elicitation of Catharanthus roseus hairy roots over time. (2009) (149)
- The effect of increasing NADH availability on the redistribution of metabolic fluxes in Escherichia coli chemostat cultures. (2002) (139)
- Process identification using neural networks (1992) (133)
- Cofactor engineering for advancing chemical biotechnology. (2013) (133)
- Efficient free fatty acid production in Escherichia coli using plant acyl-ACP thioesterases. (2011) (129)
- Replacing Escherichia coli NAD-dependent glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with a NADP-dependent enzyme from Clostridium acetobutylicum facilitates NADPH dependent pathways. (2008) (124)
- Characterization of the Acetate‐Producing Pathways in Escherichia coli (2008) (124)
- Efficient Succinic Acid Production from Glucose through Overexpression of Pyruvate Carboxylase in an Escherichia coli Alcohol Dehydrogenase and Lactate Dehydrogenase Mutant (2008) (121)
- Fed-batch culture of a metabolically engineered Escherichia coli strain designed for high-level succinate production and yield under aerobic conditions. (2005) (119)
- Effect of oxygen, and ArcA and FNR regulators on the expression of genes related to the electron transfer chain and the TCA cycle in Escherichia coli. (2005) (118)
- Metabolic engineering of the indole pathway in Catharanthus roseus hairy roots and increased accumulation of tryptamine and serpentine. (2004) (118)
- Effect of oxygen on the Escherichia coli ArcA and FNR regulation systems and metabolic responses. (2005) (117)
- Effect of ArcA and FNR on the expression of genes related to the oxygen regulation and the glycolysis pathway in Escherichia coli under microaerobic growth conditions. (2005) (117)
- Airway mechanics, gas exchange, and blood flow in a nonlinear model of the normal human lung. (1998) (115)
- Acetyl-CoA synthetase overexpression in Escherichia coli demonstrates more efficient acetate assimilation and lower acetate accumulation: a potential tool in metabolic engineering (2006) (111)
- Genetic reconstruction of the aerobic central metabolism in Escherichia coli for the absolute aerobic production of succinate. (2005) (110)
- Effect of modified glucose uptake using genetic engineering techniques on high‐level recombinant protein production in escherichia coli dense cultures (1994) (110)
- Optimization of fed‐batch penicillin fermentation: A case of singular optimal control with state constraints (1989) (107)
- The expression of 1-deoxy-D-xylulose synthase and geraniol-10-hydroxylase or anthranilate synthase increases terpenoid indole alkaloid accumulation in Catharanthus roseus hairy roots. (2011) (105)
- Effect of Overexpression of a Soluble Pyridine Nucleotide Transhydrogenase (UdhA) on the Production of Poly(3‐hydroxybutyrate) in Escherichia coli (2006) (104)
- The effects of UV‐B stress on the production of terpenoid indole alkaloids in Catharanthus roseus hairy roots (2009) (93)
- Batch culture characterization and metabolic flux analysis of succinate-producing Escherichia coli strains. (2006) (91)
- Modification of central metabolic pathway in escherichia coli to reduce acetate accumulation by heterologous expression of the bacillus subtilis acetolactate synthase gene (1994) (90)
- Metabolic engineering of Escherichia coli to minimize byproduct formate and improving succinate productivity through increasing NADH availability by heterologous expression of NAD(+)-dependent formate dehydrogenase. (2013) (88)
- Expression of a feedback‐resistant anthranilate synthase in Catharanthus roseus hairy roots provides evidence for tight regulation of terpenoid indole alkaloid levels (2004) (86)
- The effect of NAPRTase overexpression on the total levels of NAD, the NADH/NAD+ ratio, and the distribution of metabolites in Escherichia coli. (2002) (84)
- Metabolic Engineering of Escherichia coli To Enhance Recombinant Protein Production through Acetate Reduction (1995) (83)
- Enhanced Lycopene Productivity by Manipulation of Carbon Flow to Isopentenyl Diphosphate in Escherichia coli (2005) (81)
- Expression of the Arabidopsis feedback-insensitive anthranilate synthase holoenzyme and tryptophan decarboxylase genes in Catharanthus roseus hairy roots. (2006) (81)
- Studies on on‐line bioreactor identification. II. Numerical and experimental results (1984) (76)
- Effect of Sorghum vulgare phosphoenolpyruvate carboxylase and Lactococcus lactis pyruvate carboxylase coexpression on succinate production in mutant strains of Escherichia coli (2005) (76)
- Redistribution of Metabolic Fluxes in the Central Aerobic Metabolic Pathway of E. coli Mutant Strains with Deletion of the ackA‐pta and poxB Pathways for the Synthesis of Isoamyl Acetate (2008) (76)
- Cofactor engineering of intracellular CoA/acetyl-CoA and its effect on metabolic flux redistribution in Escherichia coli. (2004) (75)
- Effect of different levels of NADH availability on metabolic fluxes of Escherichia coli chemostat cultures in defined medium. (2005) (73)
- Increasing the Acetyl‐CoA Pool in the Presence of Overexpressed Phosphoenolpyruvate Carboxylase or Pyruvate Carboxylase Enhances Succinate Production in Escherichia coli (2004) (70)
- Microbial formation, biotechnological production and applications of 1,2-propanediol (2001) (67)
- Metabolic Flux Analysis ofEscherichia coliDeficient in the Acetate Production Pathway and Expressing theBacillus subtilisAcetolactate Synthase (1999) (66)
- Redistribution of metabolic fluxes in Escherichia coli with fermentative lactate dehydrogenase overexpression and deletion. (1999) (65)
- The effects of feed and intracellular pyruvate levels on the redistribution of metabolic fluxes in Escherichia coli. (2001) (64)
- Effect of acetate formation pathway and long chain fatty acid CoA-ligase on the free fatty acid production in E. coli expressing acy-ACP thioesterase from Ricinus communis. (2012) (62)
- The effect of carbon sources and lactate dehydrogenase deletion on 1,2-propanediol production in Escherichia coli (2003) (57)
- Studies on on‐line bioreactor identification. IV. Utilization of pH measurements for product estimation (1984) (56)
- Characterization of an Inducible Promoter System in Catharanthus roseus Hairy Roots (2002) (56)
- Effect of inactivation of nuo and ackA-pta on redistribution of metabolic fluxes in Escherichia coli. (1999) (55)
- Reduction of acetate accumulation in Escherichia coli cultures for increased recombinant protein production. (2008) (54)
- Effect of Modulated Glucose Uptake on High‐Level Recombinant Protein Production in a Dense Escherichia coli Culture (1994) (53)
- Succinate production from different carbon sources under anaerobic conditions by metabolic engineered Escherichia coli strains. (2011) (52)
- Improvement of Biomass Yield and Recombinant Gene Expression in Escherichia coli by Using Fructose as the Primary Carbon Source (1999) (52)
- Metabolic engineering of Escherichia coli for efficient free fatty acid production from glycerol. (2014) (52)
- Applicability of CoA/acetyl-CoA manipulation system to enhance isoamyl acetate production in Escherichia coli. (2004) (51)
- Effect of different levels of NADH availability on metabolite distribution in Escherichia coli fermentation in minimal and complex media (2004) (51)
- Effect of carbon sources differing in oxidation state and transport route on succinate production in metabolically engineered Escherichia coli (2005) (50)
- Terpenoid indole alkaloid production by Catharanthus roseus hairy roots induced by Agrobacterium tumefaciens harboring rol ABC genes. (2006) (49)
- Genetic and metabolic engineering (1998) (49)
- Improving fatty acid production in escherichia coli through the overexpression of malonyl coA‐Acyl carrier protein transacylase (2012) (48)
- Effects of terpenoid precursor feeding on Catharanthus roseus hairy roots over‐expressing the alpha or the alpha and beta subunits of anthranilate synthase (2006) (48)
- Production of succinic acid by engineered E. coli strains using soybean carbohydrates as feedstock under aerobic fermentation conditions. (2013) (47)
- Metabolic engineering of carbon and redox flow in the production of small organic acids (2015) (47)
- Chemostat culture characterization of Escherichia coli mutant strains metabolically engineered for aerobic succinate production: a study of the modified metabolic network based on metabolite profile, enzyme activity, and gene expression profile. (2005) (47)
- Metabolic impact of the level of aeration during cell growth on anaerobic succinate production by an engineered Escherichia coli strain. (2010) (46)
- Metabolic flux analysis of Escherichia coli deficient in the acetate production pathway and expressing the Bacillus subtilis acetolactate synthase. (1999) (45)
- Metabolic Flux Analysis of Escherichia coli creB and arcA Mutants Reveals Shared Control of Carbon Catabolism under Microaerobic Growth Conditions (2009) (44)
- Development of a metabolic network design and optimization framework incorporating implementation constraints: a succinate production case study. (2006) (43)
- The design of controllers for batch bioreactors (1988) (41)
- Production of isoamyl acetate in ackA-pta and/or ldh mutants of Escherichia coli with overexpression of yeast ATF2 (2004) (41)
- A note on the optimality criteria for maximum biomass production in a fed‐batch fermentor (1984) (41)
- Synthesis of methyl ketones by metabolically engineered Escherichia coli (2012) (41)
- Metabolic engineering and transhydrogenase effects on NADPH availability in escherichia coli (2013) (40)
- Effect of the global redox sensing/regulation networks on Escherichia coli and metabolic flux distribution based on C-13 labeling experiments. (2006) (40)
- Enhancement of lactate and succinate formation in adhE or pta‐ackA mutants of NADH dehydrogenase‐deficient Escherichia coli (2005) (39)
- Metabolic flux analysis of Escherichia coli expressing the Bacillus subtilis acetolactate synthase in batch and continuous cultures. (1999) (39)
- Characterization of a pH‐inducible promoter system for high‐level expression of recombinant proteins in Escherichia coli (1995) (36)
- Effect of variation of Klebsiella pneumoniae acetolactate synthase expression on metabolic flux redistribution in Escherichia coli. (2000) (35)
- Engineering poly(3‐hydroxybutyrate‐co‐3‐hydroxyvalerate) copolymer composition in E. coli (2008) (35)
- Efficient free fatty acid production from woody biomass hydrolysate using metabolically engineered Escherichia coli. (2014) (34)
- Role of the Non‐Mevalonate Pathway in Indole Alkaloid Production by Catharanthus roseus Hairy Roots (2003) (33)
- Dynamics of plasmid maintenance in a CSTR upon square‐wave perturbations in the dilution rate (1989) (32)
- Manipulating respiratory levels in Escherichia coli for aerobic formation of reduced chemical products. (2011) (31)
- Effect of sodium nitroprusside on growth and terpenoid indole alkaloid production in Catharanthus roseus hairy root cultures (2011) (31)
- The role of the octadecanoid pathway in the production of terpenoid indole alkaloids in Catharanthus roseus hairy roots under normal and UV-B stress conditions. (2009) (30)
- Transient Effects of Overexpressing Anthranilate Synthase α and β Subunits in Catharanthusroseus Hairy Roots (2005) (30)
- Long‐Term Maintenance of a Transgenic Catharanthus roseus Hairy Root Line (2007) (30)
- Effect of NADPH availability on free fatty acid production in Escherichia coli (2018) (29)
- Molecular cloning and characterization of the alcohol dehydrogenase ADH1 gene of Candida utilis ATCC 9950 (2006) (29)
- Efficient odd straight medium chain free fatty acid production by metabolically engineered Escherichia coli (2014) (29)
- Heterologous pyc gene expression under various natural and engineered promoters in Escherichia coli for improved succinate production. (2011) (29)
- Effect of culture operating conditions on succinate production in a multiphase fed-batch bioreactor using an engineered Escherichia coli strain (2011) (28)
- A pH-regulated promoter for the expression of recombinant proteins inEscherichia coli (1992) (27)
- Genetic manipulation of stationary‐phase genes to enhance recombinant protein production in Escherichia coli (1996) (27)
- Improvement of NADPH bioavailability in Escherichia coli through the use of phosphofructokinase deficient strains (2013) (25)
- Improvement of NADPH bioavailability in Escherichia coli by replacing NAD+-dependent glyceraldehyde-3-phosphate dehydrogenase GapA with NADP+-dependent GapB from Bacillus subtilis and addition of NAD kinase (2013) (24)
- Effect of the Engineered Indole Pathway on Accumulation of Phenolic Compounds in Catharanthus roseus Hairy Roots (2007) (22)
- Data analysis of plasmid maintenance in a CSTR (1989) (21)
- Improvement of butanol production in Clostridium acetobutylicum through enhancement of NAD(P)H availability (2018) (21)
- The effect of growth rate delays in substrate‐inhibited kinetics on the optimal profile of fed‐batch reactors (1986) (20)
- Flavonoid glucosides from the hairy roots of Catharanthus roseus. (2009) (20)
- Enhanced Isoamyl Acetate Production upon Manipulation of the Acetyl‐CoA Node in Escherichia coli (2004) (20)
- Characterization of an Ethanol‐Inducible Promoter System in Catharanthusroseus Hairy Roots (2007) (19)
- The YfiD protein contributes to the pyruvate formate‐lyase flux in an Escherichia coli arcA mutant strain (2007) (19)
- Five year maintenance of the inducible expression of anthranilate synthase in Catharanthus roseus hairy roots. (2009) (18)
- Characterization of alcohol dehydrogenase 1 and 3 from Neurospora crassa FGSC2489 (2007) (18)
- Protein Release in Recombinant Escherichia coli Using Bacteriocin Release Protein (1992) (18)
- Genetically constrained metabolic flux analysis. (2005) (18)
- Efficient production of free fatty acids from soybean meal carbohydrates (2015) (17)
- Metabolic transistor strategy for controlling electron transfer chain activity in Escherichia coli. (2015) (17)
- Single cell protein production from food waste using purple non-sulfur bacteria shows economically viable protein products have higher environmental impacts (2020) (16)
- Transient effects of overexpressing anthranilate synthase alpha and beta subunits in Catharanthus roseus hairy roots. (2005) (16)
- A kinetic model of oxygen regulation of cytochrome production in Escherichia coli. (2006) (16)
- Engineering Escherichia coli for odd straight medium chain free fatty acid production (2014) (15)
- Analysis of factors affecting gas exchange in intravascular blood gas exchanger. (1994) (15)
- Analysis of a framework using material balances in metabolic pathways to elucidate cellular metabolism (1989) (14)
- High yield production of four-carbon dicarboxylic acids by metabolically engineered Escherichia coli (2017) (14)
- Screening 64 cultivars Catharanthus roseus for the production of vindoline, catharanthine, and serpentine (2011) (14)
- Life cycle environmental and cost evaluation of renewable diesel production (2020) (14)
- Metabolic engineering of Escherichia coli to produce succinate from soybean hydrolysate under anaerobic conditions (2018) (14)
- Aerobic production of isoamyl acetate by overexpression of the yeast alcohol acetyl-transferases AFT1 and AFT2 in Escherichia coli and using low-cost fermentation ingredients (2008) (14)
- Effect of glucose analog supplementation on metabolic flux distribution in anaerobic chemostat cultures of Escherichia coli. (2000) (14)
- STATE ESTIMATION FOR COMPUTER CONTROL OF BIOCHEMICAL REACTORS (1981) (13)
- A New Chemical Constituent from the Hairy Root Cultures of Catharanthus roseus (2007) (13)
- Succinate production from sucrose by metabolic engineered escherichia coli strains under aerobic conditions (2011) (12)
- Effects of glycine supplement on protein production and release in recombinant Escherichia coli (1993) (12)
- Still stable after 11 years: A Catharanthus roseus Hairy root line maintains inducible expression of anthranilate synthase (2017) (12)
- Cell population heterogeneity in expression of a gene-switching network with fluorescent markers of different half-lives. (2007) (11)
- On-line Estimation of Time-varying Parameters. Application to Biochemical Reactors (1983) (11)
- Culture conditions' impact on succinate production by a high succinate producing Escherichia coli strain (2011) (11)
- Application of Gain Scheduling to the Control of Batch Bioreactors (1987) (10)
- Population dynamics of a recombinant culture in a chemostat under prolonged cultivation (1990) (10)
- Biosynthesis of Medium-Chain ω-Hydroxy Fatty Acids by AlkBGT of Pseudomonas putida GPo1 With Native FadL in Engineered Escherichia coli (2019) (10)
- Efficient free fatty acid production in engineered Escherichia coli strains using soybean oligosaccharides as feedstock (2015) (10)
- The effect of the partition locus on plasmid stability and expression of a prolonged chemostat culture. (1991) (10)
- Persistence and expression of the plasmid pBR322 inEscherichia coli K12 cultured in complex medium (1987) (9)
- Strategies for manipulation of oxygen utilization by the electron transfer chain in microbes for metabolic engineering purposes (2017) (9)
- Metabolic control of respiratory levels in coenzyme Q biosynthesis-deficient Escherichia coli strains leading to fine-tune aerobic lactate fermentation. (2015) (9)
- Metabolic engineering of the anaerobic central metabolic pathway in Escherichia coli for the simultaneous anaerobic production of isoamyl acetate and succinic acid (2009) (8)
- Continuous Production of Cell‐Free Recombinant Proteins Using Escherichia coli (1993) (8)
- Horizontal assembly of single nanowire diode fabricated by p-n junction GaN NW grown by MOCVD (2014) (7)
- Engineering E. coli Central Metabolism for Enhanced Primary Metabolite Production (2009) (6)
- Environmentally-modulated changes in fluorescence distribution in cells with oscillatory genetic network dynamics. (2009) (6)
- Optimal control policy for substrate inhibited kinetics with enzyme deactivation in an isothermal CSTR (1983) (6)
- Improved succinate production from galactose‐rich feedstocks by engineered Escherichia coli under anaerobic conditions (2019) (6)
- A comparison of two plating techniques to estimate plasmid stability of a prolonged chemostat culture (1989) (6)
- Enhanced plasmid maintenance in a CSTR upon square-wave oscillations in the dilution rate (1988) (5)
- Production of free fatty acids from switchgrass using recombinant Escherichia coli (2018) (5)
- New catharanthusopimaranoside A and B from hairy root cultures of Catharanthus roseus (2008) (5)
- New Sesquiterpene Glycosides from Culture Hairy Roots of Catharanthus roseus (2007) (5)
- Metabolic engineering of Escherichia coli to produce succinate from woody hydrolysate under anaerobic conditions (2020) (5)
- Simultaneous utilization of glucose and mannose from woody hydrolysate for free fatty acid production by metabolically engineered Escherichia coli. (2015) (5)
- Process Analysis and Identification with a Real Time Intelligent Bioreactor Supervisory Controller (1990) (4)
- Identification of new compounds from Catharanthus roseus hairy root cultures (2007) (4)
- On-Line Estimation of the State of Biochemical Reactors (1982) (4)
- Plasmid maintenance and gene expression of a recombinant culture under aerobic and anaerobic conditions (1988) (3)
- Direct bioconversion of sorghum extract sugars to free fatty acids using metabolically engineered Escherichia coli strains: Value addition to the sorghum bioenergy crop (2016) (3)
- Expression of the pfl Gene and Resulting Metabolite Flux Distribution in nuo and ackA‐pta E. coli Mutant Strains (2006) (3)
- Identification of New Compounds from Catharanthus roseus Hairy Root Cultures. (2008) (3)
- Development Of A Novel Foundation Course For Biomedical Engineering Curriculum (2001) (2)
- Design and Real Time Implementation of an Intelligent Bioreactor Control Scheme (1989) (2)
- Synergistic effect of glycine and bacteriocin release protein in the release of periplasmic protein in recombinantE. coli (1991) (2)
- Development Of Educational Materials For A Bioengineering Fundamentals Course (2006) (2)
- Development Of The Textbook, Conservation Principles In Bioengineering (2004) (1)
- Cellular and molecular engineering curriculum at Rice University (2002) (1)
- The transient effect of jasmonic acid feeding along with ORCA3 overexpression in catharanthus roseus hairy roots (2006) (1)
- Expression Systems for DNA Processes (2006) (1)
- Metabolic engineering of Escherichia coli for malate production with a temperature sensitive malate dehydrogenase (2020) (1)
- MODEL ANALYSIS OF THE EFFECTS OF PERMISSIVE HYPERCAPNIA ON CO2 REMOVAL BY IVOX, AN INTRACORPOREAL GAS EXCHANGE DEVICE (1993) (1)
- Effect of Gene Iinactivation of arcA and/or fnr in Escherichia coli on Anaerobic Metabolic Pathway (2005) (1)
- Soybean Carbohydrates as a Renewable Feedstock for the Fermentative Production of Succinic Acid and Ethanol (2014) (1)
- Genetic sensor-regulators functional in Clostridia (2020) (1)
- An expert system based intelligent control scheme for space bioreactors (1988) (1)
- Metabolic flux analysis of Escherichia coli ArcA and CreB mutants reveals shared control of carbon catabolism under microaerobic conditions of growth (2009) (1)
- Faculty Perspective Humanities Social Sciences Natural Sciences Pharmaceutical Drugs, Ethics, and Culture (0)
- Metabolic engineering of Catharanthus roseus hairy roots (2007) (0)
- Enzyme and Cofactor Engineering (2011) (0)
- Production of free fatty acids using soybean meal carbohydrates as feedstock (2015) (0)
- Metabolic engineering of biochemical pathways (2014) (0)
- 1 Metabolic engineering of carbon and redox flow in the production of small organic acids 1 2 3 (2015) (0)
- Improvement of NADPH bioavailability in Escherichia coli through the use of phosphofructokinase deficient strains (2013) (0)
- Optimal Feedback Control of a Bioreactor with a Remote Sensor (1988) (0)
- Overexpression of geraniol 10-hydroxylase and 1-deoxy-D-xyhilose 5-phosphate synthase in Catharanthus roseus hairy roots (2005) (0)
- A Program on Biochemical and Biomedical Engineering. (1989) (0)
- The Effects of Feed and Intrac Redistribution of Metabolic (2001) (0)
- Poster presentations (2007) (0)
- Metabolic Flux Analysis of Escherichia coli creB and arcA Mutants Reveals 1 Shared Control of Carbon Catabolism under Microaerobic Growth 2 Conditions (2009) (0)
- Characterization of the ecdysone agonist-inducible promoter and the ethanol inducible promoter in Catharanthus roseus hairy roots (2005) (0)
- Metabolic transistor: A new strategy for metabolic engineering (2015) (0)
- Integration Of Undergraduate Research In The Bioe Curriculum At Rice University (2005) (0)
- Studies on the on-line identification and optimal control of bioreactors (1984) (0)
- Engineering Escherichia coli for odd straight medium chain free fatty acid production (2014) (0)
- Analysis of Airway Mechanics in a Ventilated Lumped Alveolar Model Coupled with Pulmonary Gas Exchange (1994) (0)
- Cofactor engineering for short and medium chain fatty acid production in E. coli (2015) (0)
- Simulation of Gas Transport in an Intravenacaval Blood-Gas Exchange device (IVOX)© (1994) (0)
- Redistribution of Metabolic Fluxes i Lactate Dehydrogenase Ov (1999) (0)
- Escherichia coli on Cofactor Manipulation and Its istribution in Escherichia coli (2002) (0)
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