Kai Kaarniranta

Q: What Schools Are Affiliated With Kai Kaarniranta

Kai Kaarniranta is affiliated with the following schools: University of Eastern Finland, University of Helsinki

Kai Kaarniranta's AcademicInfluence.com Rankings

Kai Kaarniranta

Philosophy

#5672

World Rank

#8542

Historical Rank

Logic

#2913

World Rank

#3986

Historical Rank

philosophy Degrees

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Philosophy

Kai Kaarniranta's Degrees

Doctorate Medicine University of Helsinki
PhD Medicine University of Helsinki

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Kai Kaarniranta's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Guidelines for the use and interpretation of assays for monitoring autophagy (2012) (6925)
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 (2021) (811)
Antagonistic crosstalk between NF-κB and SIRT1 in the regulation of inflammation and metabolic disorders. (2013) (673)
AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan (2011) (644)
AMP-activated protein kinase (AMPK) controls the aging process via an integrated signaling network (2012) (577)
Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging (2008) (473)
Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP). (2012) (459)
Inflammation and its role in age-related macular degeneration (2016) (445)
Terpenoids: natural inhibitors of NF-κB signaling with anti-inflammatory and anticancer potential (2008) (390)
Inflammaging: disturbed interplay between autophagy and inflammasomes (2012) (385)
Maturation of autophagosomes and endosomes: a key role for Rab7. (2013) (339)
Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors (2009) (332)
Crosstalk between Oxidative Stress and SIRT1: Impact on the Aging Process (2013) (330)
Astrocytes in the aging brain express characteristics of senescence‐associated secretory phenotype (2011) (298)
ER stress in Alzheimer's disease: a novel neuronal trigger for inflammation and Alzheimer's pathology (2009) (289)
Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degeneration (2013) (285)
Celastrol: Molecular targets of Thunder God Vine. (2010) (273)
Impaired autophagy and APP processing in Alzheimer's disease: The potential role of Beclin 1 interactome (2013) (270)
Regulation of the aging process by autophagy. (2009) (252)
Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases (2012) (227)
Age-related macular degeneration (AMD): Alzheimer's disease in the eye? (2011) (215)
Oxidative Stress, Hypoxia, and Autophagy in the Neovascular Processes of Age-Related Macular Degeneration (2014) (206)
SIRT1: regulation of longevity via autophagy. (2009) (197)
Molecular mechanisms of retinal pigment epithelium damage and development of age‐related macular degeneration (2012) (193)
Oxidative stress activates NLRP3 inflammasomes in ARPE-19 cells--implications for age-related macular degeneration (AMD). (2012) (187)
Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers (2020) (182)
AMP‐activated protein kinase: a potential player in Alzheimer’s disease (2011) (179)
Insulin/IGF-1 paradox of aging: regulation via AKT/IKK/NF-kappaB signaling. (2010) (174)
Defects in retinal pigment epithelial cell proteolysis and the pathology associated with age-related macular degeneration (2016) (172)
Switching from a preserved to a preservative‐free prostaglandin preparation in topical glaucoma medication (2009) (160)
Polyphenol Stilbenes: Molecular Mechanisms of Defence against Oxidative Stress and Aging-Related Diseases (2015) (157)
Hsp70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation. (1998) (155)
SIRT1 longevity factor suppresses NF‐κB ‐driven immune responses: regulation of aging via NF‐κB acetylation? (2008) (154)
Mechanisms of mitochondrial dysfunction and their impact on age-related macular degeneration (2020) (150)
Amyloid-β oligomers set fire to inflammasomes and induce Alzheimer's pathology (2008) (142)
Autophagy Activation Clears ELAVL1/HuR-Mediated Accumulation of SQSTM1/p62 during Proteasomal Inhibition in Human Retinal Pigment Epithelial Cells (2013) (140)
Clearance of misfolded and aggregated proteins by aggrephagy and implications for aggregation diseases (2014) (131)
Regulatory role of HIF-1α in the pathogenesis of age-related macular degeneration (AMD) (2009) (131)
Emerging role of p62/sequestosome-1 in the pathogenesis of Alzheimer's disease (2012) (130)
Endoplasmic Reticulum Stress in Age-Related Macular Degeneration: Trigger for Neovascularization (2010) (127)
Beclin 1 interactome controls the crosstalk between apoptosis, autophagy and inflammasome activation: Impact on the aging process (2013) (126)
Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells (2007) (126)
Interaction of aging-associated signaling cascades: Inhibition of NF-κB signaling by longevity factors FoxOs and SIRT1 (2008) (125)
Hypoxia/ischemia activate processing of Amyloid Precursor Protein: impact of vascular dysfunction in the pathogenesis of Alzheimer's disease (2017) (124)
Age-related changes in AMPK activation: Role for AMPK phosphatases and inhibitory phosphorylation by upstream signaling pathways (2016) (123)
Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration (2016) (123)
Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD) (2013) (119)
Autophagy in DNA Damage Response (2015) (115)
Heat shock proteins as gatekeepers of proteolytic pathways—Implications for age-related macular degeneration (AMD) (2009) (114)
Apoptosis and aging: increased resistance to apoptosis enhances the aging process (2011) (114)
NF-κB Signaling in the Aging Process (2009) (111)
Hsp90 regulates tau pathology through co-chaperone complexes in Alzheimer's disease (2011) (109)
Control of p53 and NF-κB signaling by WIP1 and MIF: role in cellular senescence and organismal aging. (2011) (108)
ER stress and hormetic regulation of the aging process (2010) (104)
Histone demethylase Jumonji D3 (JMJD3/KDM6B) at the nexus of epigenetic regulation of inflammation and the aging process (2014) (103)
NLRP3 inflammasome activation is associated with proliferative diabetic retinopathy (2017) (99)
Role of Mitochondrial DNA Damage in ROS-Mediated Pathogenesis of Age-Related Macular Degeneration (AMD) (2019) (98)
Genetic architecture of human plasma lipidome and its link to cardiovascular disease (2019) (96)
Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90. (2008) (96)
Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration (2018) (94)
Krebs cycle intermediates regulate DNA and histone methylation: Epigenetic impact on the aging process (2014) (92)
Immunosenescence: the potential role of myeloid-derived suppressor cells (MDSC) in age-related immune deficiency (2019) (83)
PGC-1α Protects RPE Cells of the Aging Retina against Oxidative Stress-Induced Degeneration through the Regulation of Senescence and Mitochondrial Quality Control. The Significance for AMD Pathogenesis (2018) (83)
The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells (2015) (82)
Matrix metalloproteinases and their inhibitors in the chamber angle of normal eyes and patients with primary open-angle glaucoma and exfoliation glaucoma (2007) (82)
Natural thermal adaptation increases heat shock protein levels and decreases oxidative stress (2014) (81)
Stage-specific expression and cellular localization of the heat shock factor 2 isoforms in the rat seminiferous epithelium. (1998) (79)
Mitochondrial and Nuclear DNA Damage and Repair in Age-Related Macular Degeneration (2013) (79)
Efflux Protein Expression in Human Retinal Pigment Epithelium Cell Lines (2009) (78)
Analysis of variants in the complement factor H, the elongation of very long chain fatty acids-like 4 and the hemicentin 1 genes of age-related macular degeneration in the Finnish population. (2006) (77)
Cellular and molecular mechanisms of age-related macular degeneration: from impaired autophagy to neovascularization. (2013) (76)
Krebs cycle dysfunction shapes epigenetic landscape of chromatin: novel insights into mitochondrial regulation of aging process. (2014) (75)
Regulation of longevity by FGF21: Interaction between energy metabolism and stress responses (2017) (74)
Comparison of three intraocular pressure measurement methods including biomechanical properties of the cornea. (2014) (73)
Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process (2012) (73)
Impaired mitochondrial energy metabolism in Alzheimer's disease: Impact on pathogenesis via disturbed epigenetic regulation of chromatin landscape (2015) (73)
p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells (2010) (72)
Age-related macular degeneration: activation of innate immunity system via pattern recognition receptors (2009) (72)
Multifactor Effects and Evidence of Potential Interaction between Complement Factor H Y402H and LOC387715 A69S in Age-Related Macular Degeneration (2008) (71)
Lysosomes: Regulators of autophagy in the retinal pigmented epithelium. (2016) (71)
Interplay between Autophagy and the Ubiquitin-Proteasome System and Its Role in the Pathogenesis of Age-Related Macular Degeneration (2019) (70)
Epigenetic regulation of clusterin/apolipoprotein J expression in retinal pigment epithelial cells. (2007) (69)
2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process (2015) (69)
Siglec receptors and hiding plaques in Alzheimer's disease (2009) (69)
AMPK/Snf1 signaling regulates histone acetylation: Impact on gene expression and epigenetic functions. (2016) (68)
Filter-cultured ARPE-19 cells as outer blood-retinal barrier model. (2010) (68)
AMPK activation inhibits the functions of myeloid-derived suppressor cells (MDSC): impact on cancer and aging (2019) (67)
Genetics vs. entropy: Longevity factors suppress the NF-κB-driven entropic aging process (2010) (66)
Dietary Polyphenols in Age-Related Macular Degeneration: Protection against Oxidative Stress and Beyond (2019) (66)
Mechanisms of protein aggregation in the retinal pigment epithelial cells. (2010) (66)
Integrated stress response stimulates FGF21 expression: Systemic enhancer of longevity. (2017) (65)
Structure and barrier properties of human embryonic stem cell-derived retinal pigment epithelial cells are affected by extracellular matrix protein coating. (2014) (64)
ROCK, PAK, and Toll of synapses in Alzheimer's disease. (2008) (63)
Protein-oxidized phospholipid interactions in cellular signaling for cell death: from biophysics to clinical correlations. (2012) (63)
Cellular Senescence in Age-Related Macular Degeneration: Can Autophagy and DNA Damage Response Play a Role? (2017) (63)
FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process (2017) (62)
Hematopoietic mosaic chromosomal alterations increase the risk for diverse types of infection (2021) (61)
cDNA array reveals mechanosensitive genes in chondrocytic cells under hydrostatic pressure. (2002) (60)
Fisetin and luteolin protect human retinal pigment epithelial cells from oxidative stress-induced cell death and regulate inflammation (2015) (59)
Decline in cellular clearance systems induces inflammasome signaling in human ARPE-19 cells. (2014) (58)
AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms (2016) (57)
The role of myeloid-derived suppressor cells (MDSC) in the inflammaging process (2018) (56)
Glycolysis links p53 function with NF‐κB signaling: Impact on cancer and aging process (2010) (55)
Pharmacokinetics, efficacy and safety profiles of preserved and preservative‐free tafluprost in healthy volunteers (2008) (55)
Mitochondrial quality control in AMD: does mitophagy play a pivotal role? (2018) (55)
The preservative polyquaternium-1 increases cytoxicity and NF-kappaB linked inflammation in human corneal epithelial cells (2012) (54)
Hypoxia-Inducible Histone Lysine Demethylases: Impact on the Aging Process and Age-Related Diseases (2016) (54)
A prospective study on postoperative pain after cataract surgery (2013) (53)
Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome (2018) (53)
The role of polygenic risk and susceptibility genes in breast cancer over the course of life (2020) (53)
Pinosylvin-mediated protection against oxidative stress in human retinal pigment epithelial cells (2014) (52)
Benefits of switching from latanoprost to preservative-free tafluprost eye drops: a meta-analysis of two Phase IIIb clinical trials (2016) (52)
Neuronal cells show regulatory differences in the hsp70 gene response. (2002) (51)
Phytochemicals suppress nuclear factor-&kgr;B signaling: impact on health span and the aging process (2012) (50)
The effect of 17β-estradiol on IL-6 secretion and NF-κB DNA-binding activity in human retinal pigment epithelial cells (2007) (50)
DNA damage response and autophagy in the degeneration of retinal pigment epithelial cells—Implications for age-related macular degeneration (AMD) (2017) (48)
Hypoxia and inflammation in the release of VEGF and interleukins from human retinal pigment epithelial cells (2017) (47)
ER stress activates immunosuppressive network: implications for aging and Alzheimer’s disease (2020) (47)
A rat experimental model of glaucoma incorporating rapid-onset elevation of intraocular pressure (2014) (47)
Quercetin alleviates 4-hydroxynonenal-induced cytotoxicity and inflammation in ARPE-19 cells. (2015) (46)
SIRT1 regulates the ribosomal DNA locus: epigenetic candles twinkle longevity in the Christmas tree. (2009) (45)
Melatonin in Retinal Physiology and Pathology: The Case of Age-Related Macular Degeneration (2016) (44)
Phospholipase A2 in chamber angle of normal eyes and patients with primary open angle glaucoma and exfoliation glaucoma (2007) (44)
Geldanamycin increases 4-hydroxynonenal (HNE)-induced cell death in human retinal pigment epithelial cells (2005) (44)
NF-κB signaling as a putative target for ω-3 metabolites in the prevention of age-related macular degeneration (AMD) (2009) (42)
Ageing of the vitreous: From acute onset floaters and flashes to retinal detachment (2015) (42)
Clearance of autophagy-associated dying retinal pigment epithelial cells – a possible source for inflammation in age-related macular degeneration (2016) (42)
Oxidative Stress Protection by Exogenous Delivery of rhHsp70 Chaperone to the Retinal Pigment Epithelium (RPE), a Possible Therapeutic Strategy Against RPE Degeneration (2014) (41)
Mitomycin C in Revision Endoscopic Dacryocystorhinostomy: A Prospective Randomized Study (2011) (40)
Estrogen Signalling in the Pathogenesis of Age-Related Macular Degeneration (2015) (40)
Oxidative Stress is the Principal Contributor to Inflammasome Activation in Retinal Pigment Epithelium Cells with Defunct Proteasomes and Autophagy (2018) (40)
The effect of 17beta-estradiol on IL-6 secretion and NF-kappaB DNA-binding activity in human retinal pigment epithelial cells. (2007) (40)
Plant flavonol quercetin and isoflavone biochanin A differentially induce protection against oxidative stress and inflammation in ARPE-19 cells (2011) (39)
The Regulation of NFE2L2 (NRF2) Signalling and Epithelial-to-Mesenchymal Transition in Age-Related Macular Degeneration Pathology (2019) (39)
The expression of heat shock protein 27 in retinal ganglion and glial cells in a rat glaucoma model (2007) (38)
Adiponectin receptor 1 gene (ADIPOR1) variant is associated with advanced age-related macular degeneration in Finnish population (2012) (38)
Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence (2018) (38)
Symptom score questionnaire for nasolacrimal duct obstruction in adults--a novel tool to assess the outcome after endoscopic dacryocystorhinostomy. (2010) (37)
Celastrol regulates innate immunity response via NF-κB and Hsp70 in human retinal pigment epithelial cells. (2011) (37)
Primary chondrocytes resist hydrostatic pressure-induced stress while primary synovial cells and fibroblasts show modified Hsp70 response. (2001) (37)
Imiquimod in the treatment of eyelid basal cell carcinoma. (2007) (36)
Inhibition of DNA methyltransferase or histone deacetylase protects retinal pigment epithelial cells from DNA damage induced by oxidative stress by the stimulation of antioxidant enzymes. (2016) (36)
Efflux Protein Expression in Human Stem Cell-Derived Retinal Pigment Epithelial Cells (2012) (36)
Alpha-lipoic Acid modulates heat shock factor-1 expression in streptozotocin-induced diabetic rat kidney. (2007) (35)
5'-Adenosine monophosphate-activated protein kinase--mammalian target of rapamycin axis as therapeutic target for age-related macular degeneration. (2011) (35)
Immunolocalization of EMMPRIN (Cd147) in the Human Eye and Detection of Soluble Form of EMMPRIN in Ocular Fluids (2006) (35)
Transcriptional activation in chondrocytes submitted to hydrostatic pressure. (2000) (35)
Corneal epithelium as a platform for secretion of transgene products after transfection with liposomal gene eyedrops (2007) (35)
Cis-urocanic acid suppresses UV-B-induced interleukin-6 and -8 secretion and cytotoxicity in human corneal and conjunctival epithelial cells in vitro (2009) (34)
Gene expression profiles in chondrosarcoma cells subjected to cyclic stretching and hydrostatic pressure. A cDNA array study. (2003) (34)
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
Protein synthesis is required for stabilization of hsp70 mRNA upon exposure to both hydrostatic pressurization and elevated temperature (2000) (33)
Two dietary polyphenols, fisetin and luteolin, reduce inflammation but augment DNA damage-induced toxicity in human RPE cells. (2017) (32)
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
Nutraceutical with Resveratrol and Omega-3 Fatty Acids Induces Autophagy in ARPE-19 Cells (2016) (31)
High pressure effects on cellular expression profile and mRNA stability. A cDNA array analysis. (2002) (30)
Postoperative pain after cataract surgery (2013) (30)
Resveratrol as Inducer of Autophagy, Pro-Survival, and Anti-Inflammatory Stimuli in Cultured Human RPE Cells (2020) (29)
Epigenetic regulation of ASC/TMS1 expression: potential role in apoptosis and inflammasome function (2014) (29)
In vitro biocompatibility of degradable biopolymers in cell line cultures from various ocular tissues: direct contact studies. (2007) (29)
In vitro biocompatibility of degradable biopolymers in cell line cultures from various ocular tissues: extraction studies (2008) (29)
Compromised Barrier Function in Human Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells from Type 2 Diabetic Patients (2019) (28)
Autophagy – hot topic in AMD (2010) (28)
All-Trans Retinoic Acid Modulates DNA Damage Response and the Expression of the VEGF-A and MKI67 Genes in ARPE-19 Cells Subjected to Oxidative Stress (2016) (28)
Tear film proteome in age-related macular degeneration (2018) (27)
Radicicol but not geldanamycin evokes oxidative stress response and efflux protein inhibition in ARPE-19 human retinal pigment epithelial cells. (2008) (27)
Genetic Variability in DNA Repair Proteins in Age-Related Macular Degeneration (2012) (27)
Retinal arterial macroaneurysms (2014) (26)
Antimycin A-Induced Mitochondrial Damage Causes Human RPE Cell Death despite Activation of Autophagy (2019) (26)
A mouse model for Stickler's syndrome: ocular phenotype of mice carrying a targeted heterozygous inactivation of type II (pro)collagen gene (Col2a1). (2006) (26)
Hydrostatic pressure-induced changes in cellular protein synthesis. (2004) (26)
Mitophagy in the Retinal Pigment Epithelium of Dry Age-Related Macular Degeneration Investigated in the NFE2L2/PGC-1α-/- Mouse Model (2020) (26)
Geldanamycin activates Hsp70 response and attenuates okadaic acid-induced cytotoxicity in human retinal pigment epithelial cells. (2005) (25)
Expression of VEGFA‐regulating miRNAs and mortality in wet AMD (2019) (25)
Bilberries potentially alleviate stress-related retinal gene expression induced by a high-fat diet in mice (2012) (25)
Phytochemicals inhibit the immunosuppressive functions of myeloid‐derived suppressor cells (MDSC): Impact on cancer and age‐related chronic inflammatory disorders (2018) (25)
Outcome of anti-vascular endothelial growth factor therapy for neovascular age-related macular degeneration in real-life setting (2017) (25)
Endoscopic dacryocystorhinostomy as treatment for lower lacrimal pathway obstructions in adults: Review article (2015) (25)
Excipients of preservative-free latanoprost induced inflammatory response and cytotoxicity in immortalized human HCE-2 corneal epithelial cells. (2014) (24)
Cationorm shows good tolerability on human HCE-2 corneal epithelial cell cultures. (2014) (24)
NEMO shuttle: a link between DNA damage and NF-kappaB activation in progeroid syndromes? (2008) (24)
Nuclear factor E2-related factor 2 deficiency impairs atherosclerotic lesion development but promotes features of plaque instability in hypercholesterolaemic mice (2018) (24)
Increased IL-6 levels are not related to NF-κB or HIF-1α transcription factors activity in the vitreous of proliferative diabetic retinopathy. (2011) (23)
Autophagy regulating kinases as potential therapeutic targets for age-related macular degeneration. (2012) (23)
Climatic droplet keratopathy: an old disease in new clothes (2015) (23)
Fatty acids and oxidized lipoproteins contribute to autophagy and innate immunity responses upon the degeneration of retinal pigment epithelium and development of age-related macular degeneration. (2019) (22)
Altered calcium signaling in an experimental model of glaucoma. (2010) (22)
Regression of necrotizing scleritis in Wegener’s granulomatosis after infliximab treatment (2009) (22)
Potential of epigenetic mechanisms in AMD pathology. (2013) (22)
FinnGen provides genetic insights from a well-phenotyped isolated population (2023) (22)
Recovery after cataract surgery (2016) (22)
Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38MAPK, and JNK Kinase Pathways (2018) (22)
The Finnish national guideline for diagnosis, treatment and follow‐up of patients with wet age‐related macular degeneration (2017) (21)
Photoaging: UV radiation-induced inflammation and immunosuppression accelerate the aging process in the skin (2022) (21)
Differential regulation of stress proteins by high hydrostatic pressure, heat shock, and unbalanced calcium homeostasis in chondrocytic cells (2000) (21)
Long-term topical application of preservative-free prostaglandin analogues evokes macrophage infiltration in the ocular adnexa. (2016) (21)
Changes in ocular signs and symptoms in patients switching from bimatoprost–timolol to tafluprost–timolol eye drops: an open-label phase IV study (2019) (21)
Role of the Cell Cycle Re-Initiation in DNA Damage Response of Post-Mitotic Cells and Its Implication in the Pathogenesis of Neurodegenerative Diseases. (2016) (20)
Depletion of the Third Complement Component Ameliorates Age-Dependent Oxidative Stress and Positively Modulates Autophagic Activity in Aged Retinas in a Mouse Model (2017) (20)
Cis-urocanic acid inhibits SAPK/JNK signaling pathway in UV-B exposed human corneal epithelial cells in vitro (2011) (20)
Hsp90 inhibitor geldanamycin increases hsp70 mRNA stabilisation but fails to activate HSF1 in cells exposed to hydrostatic pressure. (2005) (20)
Oxidative stress plays an important role in zoledronic acid-induced autophagy. (2014) (19)
Inhibition of BET bromodomains alleviates inflammation in human RPE cells. (2016) (19)
Stress responses of mammalian cells to high hydrostatic pressure. (2003) (19)
Inflammaging Inflammaging: Disturbed Interplay between Autophagy and Inflammasomes (19)
The Finnish national guideline for diagnosis, treatment and follow‐up of patients with wet age‐related macular degeneration (2017) (18)
Life Style Intervention Improves Retinopathy Status—The Finnish Diabetes Prevention Study (2019) (18)
Trehalose for Ocular Surface Health (2020) (17)
The potential importance of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of Alzheimer’s disease (2018) (17)
Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage (2019) (17)
Specific induction of heat shock protein 90beta by high hydrostatic pressure. (2003) (16)
Influence of Hsp90 and HDAC Inhibition and Tubulin Acetylation on Perinuclear Protein Aggregation in Human Retinal Pigment Epithelial Cells (2010) (16)
Pharmacokinetics, Efficacy, and Safety of the Preservative-free Fixed Combination of Tafluprost 0.0015 % and Timolol 0.5 % in Healthy Volunteers: A Phase I Comparison vs. the Corresponding Preservative-free Monotherapies (2016) (16)
Lysosomal destabilization activates the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs) (2017) (16)
The Aging Stress Response and Its Implication for AMD Pathogenesis (2020) (15)
Insulin/IGF-1 signaling promotes immunosuppression via the STAT3 pathway: impact on the aging process and age-related diseases (2021) (15)
Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium-Role in Dead Cell Clearance and Inflammation (2019) (15)
Only IL‐1β release is inflammasome‐dependent upon ultraviolet B irradiation although IL‐18 is also secreted (2020) (14)
Contacting co‐culture of human retinal microvascular endothelial cells alters barrier function of human embryonic stem cell derived retinal pigment epithelial cells (2017) (14)
Survival and functionality of xeno‐free human embryonic stem cell–derived retinal pigment epithelial cells on polyester substrate after transplantation in rabbits (2019) (14)
Single nucleotide polymorphisms of the tenomodulin gene (TNMD) in age-related macular degeneration (2008) (14)
Regulation of ERα Signaling Pathway in Neuronal HN10 Cells: Role of Protein Acetylation and Hsp90 (2008) (14)
Exosomal vesicles enhance immunosuppression in chronic inflammation: Impact in cellular senescence and the aging process. (2020) (14)
Strong expression of HSP47 in metaplastic nasal mucosa may predict a poor outcome after primary endoscopic dacryocystorhinostomy: a prospective study (2011) (14)
Zinc and Autophagy in Age-Related Macular Degeneration (2020) (14)
Mechanistical retinal drug targets and challenges☆ (2018) (13)
MicroRNAs in the regulation of autophagy and their possible use in age-related macular degeneration therapy (2021) (13)
ADAMTS9 locus associates with increased risk of wet AMD (2014) (13)
Fibrillin-2, tenascin-C, matrilin-2, and matrilin-4 are strongly expressed in the epithelium of human granular and lattice type I corneal dystrophies (2012) (13)
Disease aetiology‐based design of multifunctional microemulsion eye drops for moderate or severe dry eye: a randomized, quadruple‐masked and active‐controlled clinical trial (2019) (12)
Cytoarchitecture of epithelial inflammatory infiltration indicates the aetiology of infectious keratitis (2017) (12)
Can vitamin D protect against age-related macular degeneration or slow its progression? (2019) (12)
SQSTM1/p62 regulates the production of IL‐8 and MCP‐1 in IL‐1&bgr;‐stimulated human retinal pigment epithelial cells (2019) (11)
Reperfusion but Not Acute Ischemia in Pig Small Intestine Induces Transcriptionally Mediated Heat Shock Response in situ (2002) (11)
Health‐related quality of life after cataract surgery with the phacoemulsification technique and intraocular lens implantation (2016) (11)
Autophagy in age-related macular degeneration (2022) (11)
Oxidative DNA Damage and Proteostasis in Age-Related Macular Degeneration (2013) (11)
Absence of collagen XVIII in mice causes age-related insufficiency in retinal pigment epithelium proteostasis (2016) (11)
Epithelial-Mesenchymal Transition and Senescence in the Retinal Pigment Epithelium of NFE2L2/PGC-1α Double Knock-Out Mice (2021) (10)
Potential of Telomerase in Age-Related Macular Degeneration—Involvement of Senescence, DNA Damage Response and Autophagy and a Key Role of PGC-1α (2021) (10)
Visual recovery of the amblyopic eye in an adult patient after loss of the dominant eye. (2003) (10)
In vitro stem cell modelling demonstrates a proof‐of‐concept for excess functional mutant TIMP3 as the cause of Sorsby fundus dystrophy (2020) (10)
Autophagy Regulates Proteasome Inhibitor-Induced Pigmentation in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells (2017) (10)
A randomized phase I clinical study of cis‐urocanic acid eye drops in healthy adult subjects (2015) (10)
Herpes simplex virus types 1 and 2 modulate autophagy in SIRC corneal cells (2014) (10)
CB2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells (2017) (10)
Immunological biomarkers of the vitreous responsible for proliferative alteration in the different forms of retinal detachment (2020) (9)
Suppressed heat shock protein response in the kidney of exercise‐trained diabetic rats (2018) (9)
Electrical synapses interconnecting axons revealed in the optic nerve head – a novel model of gap junctions’ involvement in optic nerve function (2019) (9)
Hsp70 binds reversibly to proteasome inhibitor- induced protein aggregates and evades autophagic clearance in ARPE-19 cells (2014) (9)
The first ophthalmic Choosing Wisely recommendations in Finland for glaucoma and wet age‐related macular degeneration (2019) (9)
Effects of Resvega on Inflammasome Activation in Conjunction with Dysfunctional Intracellular Clearance in Retinal Pigment Epithelial (RPE) Cells (2021) (9)
Resvega Alleviates Hydroquinone-Induced Oxidative Stress in ARPE-19 Cells (2020) (9)
UV-B-Induced Inflammasome Activation Can Be Prevented by Cis-Urocanic Acid in Human Corneal Epithelial Cells (2020) (9)
Oxidative Stress, Epigenetics, Environment, and Epidemiology of Diabetic Retinopathy (2017) (8)
Role of antioxidant enzymes and small molecular weight antioxidants in the pathogenesis of age-related macular degeneration (AMD) (2013) (8)
Inflammation and its role in age-related macular degeneration (2016) (8)
Histopathology of the three implanted degradable biopolymers in rabbit eye. (2009) (8)
Best‐corrected visual acuity and retinal thickness are associated with improved cortical visual processing in treated wet AMD patients (2014) (8)
Increased intraocular pressure alters the cellular distribution of HuR protein in retinal ganglion cells - A possible sign of endogenous neuroprotection failure. (2018) (7)
TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells (2021) (7)
Oxidized low‐density lipoprotein, lipid and calcium aggregates reveal oxidative stress and inflammation in the conjunctiva of glaucoma patients (2017) (7)
Changes in neurophysiologic markers of visual processing following beneficial anti-VEGF treatment in macular degeneration (2013) (7)
Differential Expression of Inflammasome-Related Genes in Induced Pluripotent Stem-Cell-Derived Retinal Pigment Epithelial Cells with or without History of Age-Related Macular Degeneration (2021) (7)
Oxidative stress activates NLRP3 inflammasomes in ARPE‐19 cells (2012) (7)
Recovery and patient satisfaction after cataract surgery. A one‐year prospective follow‐up study (2015) (7)
Dysregulated Tear Film Proteins in Macular Edema Due to the Neovascular Age-Related Macular Degeneration Are Involved in the Regulation of Protein Clearance, Inflammation, and Neovascularization (2021) (7)
DICER1 in the Pathogenesis of Age-related Macular Degeneration (AMD) - Alu RNA Accumulation versus miRNA Dysregulation (2020) (7)
Potential Role of Myeloid-Derived Suppressor Cells (MDSCs) in Age-Related Macular Degeneration (AMD) (2020) (7)
Autophagy Genes for Wet Age-Related Macular Degeneration in a Finnish Case-Control Study (2020) (6)
Hypoxia/ischemia impairs CD33 (Siglec-3)/TREM2 signaling: Potential role in Alzheimer's pathogenesis (2021) (6)
Drug Flux Across RPE Cell Models: The Hunt for An Appropriate Outer Blood–Retinal Barrier Model for Use in Early Drug Discovery (2020) (6)
Therapeutic potential of PGC-1α in age-related macular degeneration (AMD) – the involvement of mitochondrial quality control, autophagy, and antioxidant response (2021) (6)
Topical cis-urocanic acid prevents ocular surface irritation in both IgE -independent and -mediated rat model (2017) (6)
Comparison of Two Different Treat-and-Extend Protocols with Aflibercept in Wet Age-Related Macular Degeneration: Two-Year Results (2020) (5)
Hypoxic conditions stimulate the release of B‐type natriuretic peptide from human retinal pigment epithelium cell culture (2014) (5)
Hypoxia and inflammation in human retinal cells (2016) (5)
Wound healing of human embryonic stem cell-derived retinal pigment epithelial cells is affected by maturation stage (2018) (5)
Bevacizumab does not affect autophagy clearance during proteasomal inhibition in human retinal pigment epithelial cells (2014) (5)
Influence of selective estrogen receptor modulators on interleukin-6 expression in human retinal pigment epithelial cells (ARPE-19). (2010) (5)
Nature-Inspired Hybrids (NIH) Improve Proteostasis by Activating Nrf2-Mediated Protective Pathways in Retinal Pigment Epithelial Cells (2022) (5)
2-Oxoglutarate-dependent dioxygenases are sensors of energy metabolism, oxygen availability, and iron homeostasis: potential role in the regulation of aging process (2015) (5)
Epithelial–mesenchymal transition‐related serum markers ET‐1, IL‐8 and TGF‐β2 are elevated in a Finnish wet age‐related macular degeneration cohort (2021) (5)
Biocompatibility of Different Poly(Lactide-Coglycolide) Polymers Implanted into the Subconjunctival Space in Rats (2011) (5)
Hsp 90 inhibition as a means to inhibit activation of the NLRP 3 inflammasome (2018) (5)
Autophagy in the eye: A double-edged sword (2012) (5)
Inflammation as a target of minocycline: special interest in the regulation of inflammasome signaling (2014) (5)
Induction of Heat Shock Protein 70 in Mouse RPE as an In Vivo Model of Transpupillary Thermal Stimulation (2020) (4)
Retinal haemorrhages in shaken baby syndrome (2009) (4)
[Pathogenesis of age-related macular degeneration - dialogue between autophagy and inflammasomes] . (2017) (4)
Potential of Long Non-Coding RNAs in Age-Related Macular Degeneration (2021) (4)
Responses of mammalian cells to mechanical forces (2001) (4)
Ultrasound and Microbubbles for the Treatment of Ocular Diseases: From Preclinical Research towards Clinical Application (2021) (4)
Upregulation of inflammatory genes in the nasal mucosa of patients undergoing endonasal dacryocystorhinostomy (2014) (4)
Antimycin A-induced mitochondrial dysfunction regulates inflammasome signaling in human retinal pigment epithelial cells. (2021) (4)
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells (2020) (4)
Molecular Mechanisms Underlying Age-Related Ocular Diseases (2018) (4)
Hsp 70 accumulation in chondrocytic cells exposed to high continuous hydrostatic pressure coincides with mRNA stabilization rather than transcriptional activation ( heat shock transcription factor y heat shock element y cartilage (1998) (4)
Interplay between aging and other factors of the pathogenesis of age-related macular degeneration (2022) (4)
A novel proteotoxic stress associated mechanism for macular corneal dystrophy. (2015) (3)
Correlation between the rate of intravitreal injections, use of aflibercept as a second‐line treatment and visual impairment for wet AMD in Finland (2020) (3)
An expanded analysis framework for multivariate GWAS connects inflammatory biomarkers to functional variants and disease (2020) (3)
Oxidative stress induces mitochondrial dysfunction and autophagy in ARPE‐19 cells (2019) (3)
Preferences and ease of use of preservative-free IOP-lowering eye drop containers: A comparison of two multi-dose bottles (2018) (3)
Prevention of autophagy activates inflammasome signaling in ARPE-19 cells treated with a proteasome inhibitor (2013) (3)
Real Life Experience of Dexamethasone Implant in Refractory Diabetic Macular Oedema (2019) (3)
Leucine 7-proline 7 polymorphism in the signal peptide of neuropeptide Y is not a risk factor for exudative age-related macular degeneration. (2006) (3)
The Effect of Dietary Supplementations on Delaying the Progression of Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis (2022) (3)
Oxidative Stress and Mitochondrial Damage in Dry Age-Related Macular Degeneration Like NFE2L2/PGC-1α -/- Mouse Model Evoke Complement Component C5a Independent of C3 (2021) (3)
Association of the MYOC p.(Gln368Ter) Variant With Glaucoma in a Finnish Population. (2021) (3)
Immunosenescence: the potential role of myeloid-derived suppressor cells (MDSC) in age-related immune deficiency (2019) (3)
Polygenic and clinical risk scores and their impact on age at onset and prediction of cardiometabolic diseases and common cancers (2020) (2)
Wound healing of human embryonic stem cell-derived retinal pigment epithelial cells is affected by maturation stage (2018) (2)
Incidence of cataract surgeries in people with and without Alzheimer’s disease (2021) (2)
Visual processing in patients with age-related macular degeneration performing a face detection test (2017) (2)
Serum Levels of Plasmalogens and Fatty Acid Metabolites Associate with Retinal Microangiopathy in Participants from the Finnish Diabetes Prevention Study (2021) (2)
Hormetic Heat Shock Enhances Autophagy through HSF1 in Retinal Pigment Epithelium Cells (2022) (2)
Maculopathy in Pierre Robin sequences. (2007) (2)
Longitudinal observation of the retinal nerve fibre layer in glaucoma patients treated with brimonidine combined with timolol or timolol alone (2017) (2)
Expression of Efflux Proteins in ARPE–19 Cells and in Primary RPE Cells (2006) (2)
Effect of cataract surgery on wet age‐related macular degeneration activity (2021) (2)
Influence of Hsp 90 and HDAC Inhibition and Tubulin Acetylation on Perinuclear Protein Aggregation in Human Retinal Pigment Epithelial Cells (2014) (2)
Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells (2021) (2)
The Nobel Prized cellular target autophagy in eye diseases (2017) (2)
cis-Urocanic acid prevents inflammation and cell death in UVB-treated ARPE-19 cells (2015) (1)
Overlap of Genetic Loci for Central Serous Chorioretinopathy With Age-Related Macular Degeneration. (2023) (1)
Incidence of cataract surgeries in relation to diagnosis of Parkinson's disease. (2022) (1)
Taking a roller coaster ride with autophagy markers p62 and LC3 (2016) (1)
A novel proteotoxic stress‐associated mechanism for macular corneal dystrophy (2014) (1)
Warfarin use among wet AMD patients (2016) (1)
Cis‐urocanic acid inhibits conjunctivitis and blepharitis in rat model of acute eye irritation (2012) (1)
Pinosylvin protects retinal pigment epithelial cells from oxidative stress by activating Nrf2‐mediated antioxidant defence system (2014) (1)
[Surgery for lower nasolacrimal duct obstructions in adults]. (2012) (1)
Individual benefits of enoxaparin treatment in branch vein occlusion (2018) (1)
Pinosylvin Extract Retinari™ Sustains Electrophysiological Function, Prevents Thinning of Retina, and Enhances Cellular Response to Oxidative Stress in NFE2L2 Knockout Mice (2021) (1)
Cis‐urocanic acid eye drops are safe and well tolerated in healthy adults – results from a randomised phase 1 clinical study (2012) (1)
Pharmacokinetics of preserved and preservative-free formulations of tafluprost are comparable in healthy volunteers (2007) (1)
Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population (2023) (1)
NLRP3 inflammasome activation after ultraviolet B irradiation in human corneal epithelial cells (2016) (1)
BDNF-deficiency Downregulates SIRT1 and Upregulates SIRT2 Expression in Aging Mouse Retina (2011) (1)
How to study autophagy in RPE cells? (2011) (1)
Inflammaging Signaling in Health Span and Life Span Regulation: Next Generation Targets for Longevity (2014) (1)
The role of p62/SQSTM1 in IL-1β -mediated cytokine production in retinal pigment epithelial cells (2017) (1)
A Linkage between Angiogenesis and Inflammation in Neovascular Age-Related Macular Degeneration (2022) (1)
Cytoskeleton and Proteoglycan Synthesis in Chondrocytes Under Hydrostatic Pressure (1999) (1)
[Age-related macular degeneration--a difficult problem for the patient and for the ophthalmologist]. (2003) (1)
Hydroquinone predisposes for retinal pigment epithelial (RPE) cell degeneration in inflammatory conditions (2022) (1)
Serum endothelin 1 and interleukin 8 are elevated in patients with active wet age‐related macular degeneration without a clear serological link to epithelial‐mesenchymal transition: a Finnish cohort (2022) (1)
ER stress activates immunosuppressive network: implications for aging and Alzheimer’s disease (2020) (1)
Stillbene compounds induce dynamic autophagy and decrease protein aggregation during proteasome inhibition (2017) (1)
Mitochondrial quality control in AMD: does mitophagy play a pivotal role? (2018) (1)
MicroRNA regulation underlines an interplay between autophagy and neovascularization in wet AMD (2018) (0)
Increased intraocular pressure causes deficiency in the level of ELAVL1/HuR cytoplasmic fraction in the retina (2016) (0)
This issue of ACTA (2022) (0)
Myeloid-derived suppressor cells (MDSC): an important partner in cellular/tissue senescence (2018) (0)
The cytoprotective role of heat shock proteins and geldanamycin in human retinal pigment epithelial cells subjected to protein phosphatase inhibitor (2004) (0)
Polyphenolic compounds reduce inflammation in ARPE‐19 cells (2012) (0)
Oxidative Stress Protection by Exogenous Delivery of rhHsp70 Chaperone to the Retinal Pigment Epithelium (RPE), a Possible Therapeutic Strategy Against RPE Degeneration (2014) (0)
Subject Index Vol. 34, 2002 (2002) (0)
The potential importance of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of Alzheimer’s disease (2018) (0)
FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process (2016) (0)
Retinal Pigment Epithelium in Age-Related Macular Degeneration (2020) (0)
AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms (2016) (0)
Hydroquinone increases risk for retinal pigment epithelial (RPE) cell degeneration (2022) (0)
Selective proteasome inhibition activates AIM2 inflammasome in human retinal pigment epithelium cells (2022) (0)
The molecular role of the Six6 transcription factor in glaucoma (2018) (0)
The cover photo shows different neovascularization types from the paper by Smid et al. (2021) (0)
This issue of ACTA, printed and electronic (2020) (0)
CB2 receptor activation causes an ERK1/2-dependent inflammatory response in human RPE cells (2017) (0)
Retraction: Hellinen et al. Drug Flux across RPE Cell Models: The Hunt for an Appropriate Outer Blood–Retinal Barrier Model for Use in Early Drug Discovery. Pharmaceutics 2020, 12, 176 (2022) (0)
Autophagy stimulus promotes HuR protein phosphorylation and SQSTM1/p62 protein up‐regulation in ARPE‐19 cells (2014) (0)
The HuR/ELAVL1 expression is altered in Nrf2‐deficient contexts (2019) (0)
Cytoplasmic SQSTM1/p62, ubiquitin and ELAVL1/HuR proteins in foveomacular, perimacular and peripheral RPE cells. (2013) (0)
Increased variability in visual evoked potentials following markedly improved visual acuity after anti-VEGF intravitreal injections in macular degeneration (2018) (0)
What is the meaning of autofluorescence in retinal diseases (2017) (0)
Nuclear factor-erythroid 2-related factor-2 (Nrf2) and peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) regulates proteolysis in cornea (2015) (0)
Inflammasome activation by oxidative stress in ARPE‐19 cells (2012) (0)
Visual impairment due to age‐related macular degeneration during 40 years in Finland and the impact of novel therapies (2022) (0)
The most successful year in the history of Acta Ophthalmologica (2021) (0)
Possible association with obesity-related loci and outcome of wet AMD (2016) (0)
This issue of ACTA, printed and electronic (2020) (0)
Circadian control and proteostasis in NRF-2/PGC-1 alpha knock-out mice (2018) (0)
Increased TRAIL and TRAIL receptor expression in rat corneal stroma exposed to chemical burn damage (2018) (0)
Cellular Expression of Heat Shock Protein 25 in Retinal Ganglion Cells in Rat Glaucoma Model (2006) (0)
This issue of ACTA (2022) (0)
AICAR promotes cleansing of MG-132-induced protein aggregates in ARPE-19 cells (2013) (0)
This issue of ACTA (2021) (0)
Autophagy in the regulation of retinal pigment epithelium para-inflammation and age-related degeneration (2016) (0)
Regulatory differences of the hsp70 gene response in mammalian cells (Nisäkässolujen stressigeenin (hsp70) säätelypoikkeavuudet) (2002) (0)
Serum adiponectin associates with aging rather than neovascular AMD (2017) (0)
From biomarker discovery to proteomic validation using mass spectrometry (2018) (0)
[Pathogenesis of age-related macular degeneration]. (2009) (0)
Rab 7 characterization and its regulatory role on autophagy in retinal pigment epithelium cells (2018) (0)
Management of epithelial malignancies (radiotherapy and local chemotherapy) (2018) (0)
Animal case (2018) (0)
This issue of ACTA (2022) (0)
AMPK activation inhibits the functions of myeloid-derived suppressor cells (MDSC): impact on cancer and aging (2019) (0)
Absence of collagen XVIII in mice causes age-related insufficiency in retinal pigment epithelium proteostasis (2016) (0)
Resvega alleviates oxidative stress and inflammasome activation in retinal pigment epithelial cells (2019) (0)
Proteostasis is age‐related macular degeneration (2022) (0)
Quercetin counteracts the cellular damage caused by HNE and inhibits inflammation in ARPE-19 cells (2013) (0)
Oxidative stress in retinal pigment epithelial cells: protective effect of wood‐derived phenolic compounds (2012) (0)
This issue of ACTA 100‐4 (2022) (0)
Innovation and advances in bioelectronic medicine progressing to address atrophic dry AMD with wireless sub‐retinal photovoltaic implant (2018) (0)
Acta Ophthalmologica for 100 years (2023) (0)
Reactive astrocytosis alters gene expression of ECM components in primary optic nerve head astrocytes (2018) (0)
Shortening of Saccades as a Possible Easy-to-Use Biomarker to Detect Risk of Alzheimer’s Disease (2022) (0)
Aging and BDNF‐deficiency upregulates heat shock protein expression in mouse retina (2011) (0)
Alleviation of inflammation in human RPE cells by bromodomain inhibitors is independent of SIRT1 (2016) (0)
Epoxomicin, a Selective Proteasome Inhibitor, Activates AIM2 Inflammasome in Human Retinal Pigment Epithelium Cells (2022) (0)
The barrier function, autophagy and inflammatory responses are similar under diabetic stimuli in retinal pigment epithelial cells derived from human induced pluripotent stem cells from the diabetic patients and the normal controls (2017) (0)
HYALURONAN STIMULATES KERATINOCYTE MIGRATION AND ACTIVATES THE TRANSCRIPTION FACTOR AP-1 IN KERATINOCYTES THROUGH THE JNK PATHWAY (2002) (0)
Seeing is believing: live imaging of microvascular pathology in glaucoma (2018) (0)
Microglial cell inhibition improves photoreceptor survival in two animal models of inherited retinal degeneration (2018) (0)
Effects of high hydrostatic pressure on mammalian chondrocytes and HeLa cells (2000) (0)
Effect of Pseudomonas and Acanthamoeba infection upon inflammation produced by human cornea epithelial cells (2018) (0)
Lack of collagen XVIII in mice evokes age-dependent deficiency in retinal pigment epithelium proteostasis (2015) (0)
Electrical synapses interconnecting axons in the optic nerve head–a novel model of optic nerve function (2019) (0)
Juxtanuclear Protein Aggregation Is Regulated By Heat Shock Proteins And Microtubulus Acetylation In Human Arpe–19 Cells (2006) (0)
Biomarkers of Age‐Related Macular Degeneration (AMD): Four new obesity‐related genetic loci are associated with advanced AMD (2014) (0)
Activation of Nrf2‐mediated protective pathways by nature‐inspired hybrids improves proteostasis in retinal pigment epithelial cells (2022) (0)
Hyaluronan increases the level of activation protein-1 (AP-1) in cultured epidermal keratinocytes (1998) (0)
Antioxidants and mitochondria connection in the regulation of autophagy (2018) (0)
The role of vision‐related problems in fatal road accidents in Finland (2020) (0)
Nrf-2 and PGC1-alpha deletion affects ultrastructural changes in retinal pigmented epithelium associated with the changes of oxidative stress and autophagy markers expression pattern in compound null mice (2017) (0)
Matrix Metalloproteinases And Their Inhibitors In Human Trabecular Meshwork (2006) (0)
Soluble and membrane-bound adenylate kinase and nucleotidases augment ATP-mediated inflammation in diabetic retinopathy eyes with vitreous hemorrhage (2019) (0)
Mitochondrial impairment regulates inflammasome activation in human retinal pigment epithelial cells (2017) (0)
This issue of ACTA (2021) (0)
Evidence of neuroplasticity in the human visual cortex following beneficial anti‐VEGF treatment in exudative age‐related macular degeneration (2012) (0)
UK trainee trabeculectomy outcomes incorporating simulated surgery (2018) (0)
Comparison of the retinal measurements of standard and neurological SD-OCT applications in MS patients (2016) (0)
Structural impact of arrested foveal development in preterms (2018) (0)
Proteasome inhibitor ‐induced protein aggregation is regulated via HSP90, HDACs and microtubulus stability in ARPE‐19 cells (2009) (0)
5xFAD mouse model develops visual dysfunction together with protein aggregation (2022) (0)
The Effect of Increased Intraocular Pressure on Astrocytes in Rat Glaucoma Model (2006) (0)
Red clover (Trifolium pratense L.): Identification and characterization of phenolic compounds and protective action against oxidative stress and inflammation (2010) (0)
Activation of cannabinoid receptor CB2 in ARPE‐19 cells stimulates the release of inflammatory cytokines via activation of the ERK pathway (2014) (0)
Autophagy protects retinal pigment epithelial cells from hydroquinone‐induced toxicity (2022) (0)
This Issue of ACTA (2022) (0)
Autophagy regulates death of retinal pigment epithelium cells in age-related macular degeneration (2016) (0)
Autophagy induction decreases protein aggregation in response to polyphenolic pinosylvin and heat shock exposures in ARPE-19 cells (2017) (0)
p38/MAPK is required for protein aggregate formation and removal by autophagy upon proteasome dysfunction (2022) (0)
In vivo modified peripheral glia enhance regenerative capacity in a rat retina (2015) (0)
Basics for ultrastructures in transmission electron microscopy (2019) (0)
Ex vivo expansion of human primary RPEs for potential use in clinical transplantation studies (2018) (0)
NRF‐2 and PGC‐1α signaling regulate epithelial‐mesenchymal transition in mouse model (2019) (0)
AICAR induces effectively autophagy clearance in ARPE‐19 cells (2012) (0)
The best corrected visual acuity and retinal thickness are associated with improved cortical visual processing in treated wet‐AMD patients (2014) (0)
The effect of eliminating tear evaporation on tear osmolarity (2018) (0)
Heat shock response during ischemia and reperfusion in pig small intestine in vivo (2000) (0)
Crosstalk of proteasomes and autophagy in RPE cells (2013) (0)
Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata (2023) (0)
Impact of two different prostaglandin preparations on human corneal epithelial cells (HCE-2) in in vitro conditions (2013) (0)
The cleavage of Gasdermin E is the rate limiting step in the secretion of IL ‐1β in RPE cells with non‐functional cellular clearance (2022) (0)
The p62/sequestosome 1 binds irreversibly to protein aggregates prior to autophagy clearance in ARPE‐19 cells (2012) (0)
Effect of geldanamycin on the NLRP3 inflammasome in human retinal pigment epithelial cells (2016) (0)
[Not Available]. (2007) (0)
Techniques for studying mechanisms of autophagy in RPE cells (2013) (0)
Mapping of Calcium Signalling in Rat Retina in an Experimental Model of Glaucoma (2009) (0)
The Nrf2 and PGC-1α deficient murine retina reveals retinal pigment epithelium damage that coincides with autophagy decline and damaged mitochondria. (2017) (0)
Retinal biomarkers for Alzheimer's and Parkinson's diseases (2018) (0)
Histone demethylase Jumonji D3 (JMJD3/KDM6B) at the nexus of epigenetic regulation of inflammation and the aging process (2014) (0)
Effect of resveratrol on RPE cells and its potential role in AMD prevention (2014) (0)
Autophagy stimulus affects different kinase pathways and promotes HuR protein activation and SQSTM1/p62 protein synthesis in ARPE-19 cells (2015) (0)
Oxidative stress and mitochondrial damage evoke complement component C5 activation independent of component C3 in dry age‐related macular degeneration like NFE2L2/ PGC‐1α ‐/‐ mouse model (2022) (0)
In this issue (2021) (0)
Herpes simplex virus types 1 and 2 modulate autophagy in SIRC corneal cells (2014) (0)
NRF-2/PGC-1α deficiency induces retinal degeneration in mice (2018) (0)
Hypoxia induces an inflammatory response in ARPE-19 cells (2015) (0)
Down‐regulated tear film proteins in neovascular age‐related macular degeneration are involved in the regulation of protein clearance, inflammation, neovascularization and apoptosis (2021) (0)
SQSTM1/p62 depletion leads to the Rab7 accumulation and inflammatory response in ARPE-19 cells (2015) (0)
Successful years of collaboration between Acta Ophthalmologica and the European Association for Vision and Eye Research (2021) (0)
Comparison of barrier properties of outer blood-retinal barrier models - human stem cell-based models as a novel tool for ocular drug discovery. (2023) (0)
Resvega in the regulation of autophagy (2016) (0)
Role of HSP70 and p62 in regulation of autophagy clearance in ARPE‐19 cells (2009) (0)
An in vitro model of outer blood-retinal barrier based on human embryonic stem cell derived retinal pigment epithelial cells and human retinal microvascular endothelial cells (2015) (0)
AICAR induces autophagy in ARPE‐19 cells (2011) (0)
Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes (2022) (0)
Lysosomal destabilization activates the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs) (2017) (0)
Identification of eleven differentially expressed proteins in the tear film of patients with neovascular Age‐related Macular Degeneration (AMD) (2022) (0)
Crosstalk of protein clearance, inflammasome, and Ca2+ channels in retinal pigment epithelium derived from age-related macular degeneration patients. (2023) (0)
Autophagy and inflammation related RNA levels are elevated in Finnish age‐related macular degeneration patient blood serum (2022) (0)
Triple procedure for treating advanced AAK with cataract (2018) (0)
Ultraviolet irradiation induces the secretion of IL-1β via activation of NLRP3 inflammasomes in human retinal pigment epithelial cells (2017) (0)
This issue of ACTA (2021) (0)
Synaptic coupling of unmyelinated optic nerve axons – a novel insight into optic nerve structure and conductivity properties (2018) (0)
Face stimulus challenges visual processing in age-related macular degeneration (2016) (0)
Contents Vol. 34, 2002 (2002) (0)
HSP70 and p62/SQSTM 1 regulate differently autophagy clearance in ARPE‐19 cells (2009) (0)
Hsp25 and Hsc70 Expression in Retina of trkB Transgenic Mice and Their Wild–Type Controls (2005) (0)
Resveratrol As Inducer Of Autophagy And Prosurvival Stimulus In Cultured ARPE-19 Cells (2011) (0)
Investigating the movement of the centre of the multifocal hexagonal stimulus array using an electroretinogram function (2018) (0)
Secretory autophagy is increased in 5xFAD mice (2022) (0)
This issue of Acta Feb 2021 (2021) (0)
Geldanamycin Increases 4–Hydroxynonenal (HNE) –Induced Cytotoxic Effects in Human Retinal Pigment Epithelial Cells (2005) (0)
Loss of Nrf-2 and PGC1-alpha genes changes macromorphology of the eye and evokes microstructural and pigmentation pattern changes of the retinal pigmented epithelium (2017) (0)
BDNF‐deficiency upregulates SIRT2 expression but does not affect cellular metabolism in mouse retina (2011) (0)
The efficacy of dexamethasone implant (Ozurdex 700 μg) in refractory diabetic macular oedema (2014) (0)
Circadian Control and Pinosylvin Treatment in the Disease Model of Age‐related Macular Degeneration (2019) (0)
Switching from latanoprost to preservative-free tafluprost (2008) (0)
Efflux proteins of outer blood-retinal barrier (2007) (0)
Proteolysis in RPE cells (2007) (0)
Microglia–Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model (2022) (0)
Nuclear factor-erythroid 2-related factor-2 (Nrf2) and peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α) deficient mice: Dissecting the antioxidant regulation pathways affects retinal autophagy (2016) (0)
Mechanisms behind the protein aggregation-related inflammasome activation in RPE cells (2016) (0)
Inflammasome activation by UVB irradiation in human corneal epithelial cells (2015) (0)
This issue of ACTA (2021) (0)
NF-κB signaling as a putative target for omega-3 metabolites in the prevention of age-related macular degeneration (AMD) (2020) (0)
Macular retinal capillary density and blood flow differences between black and white subjects using optical coherence tomography angiography (2018) (0)
Epigenetic regulation of ASC/TMS1 expression: potential role in apoptosis and inflammasome function (2013) (0)
Relation of biometric eye profile with intraocular pressure corrections in healthy myopes (2012) (0)
Role of proteasomal proteolysis in the pathogenesis of macular corneal dystrophy (2014) (0)
Non-Coding RNAs Regulating Mitochondrial Functions and the Oxidative Stress Response as Putative Targets against Age-Related Macular Degeneration (AMD) (2023) (0)
Selective estrogen receptor modulators regulate IL-6 inflammatory response in ARPE-19 cells (2008) (0)
[From research of cellular stress to various clinical break through innovations?]. (2001) (0)
Pinosylvin extract Retinari™ sustains electrophysiological function, prevents thinning of retina and enhances cellular response to oxidative stress in NFE2L2 knock‐out mice (2022) (0)
Acta Ophthalmologica 2021 (2022) (0)
Topical treatment of diabetic macular edema using dexamethasone ophthalmic suspension: A randomized, double‐masked, vehicle‐controlled study (2022) (0)
Structural Alterations in the Mouse Eye After a Targeted Heterozygous Inactivation of Type II (Pro)Collagen Gene (Col2a1) (2005) (0)
Disease etiology‐based design of multifunctional trehalose emulsion eye drops for moderate or severe dry eye: a randomised, quadruple‐masked and active‐controlled clinical trial (2019) (0)
This issue of Acta (2022) (0)
Activation of NLRP3 by intracellular aggregates in RPE cells (2017) (0)
Oxidative stress and mitochondrial damage overloads mitophagy in dry age‐related macular degeneration like PGC‐1α/Nrf‐2 knockout mice model (2018) (0)
Bafilomycin A1 enhances the production of IL-1b induced by the proteasome inhibitor MG-132 but not that of IL-8 (2013) (0)
Secretory autophagy: a turn key for understanding AMD pathology and developing new therapeutic targets? (2022) (0)
Luteolin decreases mitochondrial damage-associated inflammation in human retinal pigment epithelial cells (2017) (0)
Single nucleotide polymorphisms in pigmentation‐related dopachrome tautomerase and melanocortin‐1 receptor genes are associated with wet age‐related macular degeneration in a Finnish cohort (2022) (0)
Refractive error and forward light scatter (2018) (0)
Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome (2018) (0)
Nrf2- and PGC-1α -deficient mice: A novel animal model for disturbed proteostasis and RPE degeneration (2016) (0)
Autophagy machinery is functional in human pluripotent stem cell-derived retinal pigment epithelial cells (2016) (0)
Human Embryonic Stem Cell-derived Retinal Pigment Epithelial Cells Express Functional Multidrug Resistance Associated Protein (MRP) 1 (2011) (0)
Resvega induces autophagy and prevents ARPE‐19 cell damage during proteasome inhibition (2016) (0)
New nature‐inspired hybrids activating the Nrf2‐HO1 pathway in retinal pigment epithelial cells and their potential use in pathologies featured by oxidative stress (2018) (0)
Hypoxia stimulates the release of Brain Natriuretic Peptide (BNP) from RPE cells (2013) (0)
Effects of HSP90 inhibitor TAS-116 on the inflammasome activation in ARPE-19 cells (2017) (0)
Can we individualize glaucoma surgery? (2018) (0)
Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases (2012) (0)
Computer-based Eye-tracking Analysis of King-Devick Test Differentiates Persons With Idiopathic Normal Pressure Hydrocephalus From Cognitively Unimpaired (2022) (0)
The state of your journal Acta Ophthalmologica 2020 (2021) (0)
Inhibition of prolyl oligopeptidase: A promising pathway to prevent the progression of age-related macular degeneration. (2021) (0)
Cis-urocanic acid, a novel anti-inflammatory and cytoprotective drug, decreases effectively UVB-induced IL-6 secretion and cytotoxicity in human corneal and conjunctival epithelial cells in vitro (2008) (0)
Predegenerated Schwann cells promote neuroprotection and regeneration of retinal ganglion cells in ex vivo rat retinal explants (2014) (0)
Proteasome Inhibitor–Induced Cytoplasmic Protein Aggregation Is Modified With Geldanamycin in Human ARPE–19 Cells (2005) (0)
Inhibition of adaptor proteins MAVS and TXNIP reduces inflammasome activation in RPE cells (2019) (0)
Nrf2‐ and PGC‐1α‐deficient mice: A novel animal model for impaired autophagy in AMD? (2015) (0)
Is that a torpedo near the fovea? Torpedo maculopathy a case report (2018) (0)
Decreased occurrence of early diabetic retinopathy in lifestyle intervention group of the Finnish Diabetes Prevention Study (2018) (0)
Fisetin and Luteolin decrease inflammation and oxidative stress-induced cytotoxicity in ARPE-19 cells (2015) (0)
Structure of Collagen fibril and proteoglycans at different depth of corneal stroma of CXL treated rats (2014) (0)

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What Schools Are Affiliated With Kai Kaarniranta?

Kai Kaarniranta is affiliated with the following schools: