Kairbaan Hodivala-Dilke

Kairbaan Hodivala-Dilke's AcademicInfluence.com Rankings

Biology

#14362

World Rank

#18091

Historical Rank

Cell Biology

#834

World Rank

#853

Historical Rank

biology Degrees

Download Badge

Biology

Why Is Kairbaan Hodivala-Dilke Influential?

(Suggest an Edit or Addition)

According to Wikipedia, Kairbaan Hodivala-Dilke, FMedSci is an English cell biologist who has made significant contributions to the understanding of the cellular and molecular biology of the tumour microenvironment and in particular angiogenesis. She is Professor of Angiogenesis and the Tumour Microenvironment and Deputy Institute Director of Barts Cancer Institute, Queen Mary University of London. In 2015 she was awarded the Hooke medal from the British Society for Cell Biology and EMBO membership.

(See a Problem?)

Kairbaan Hodivala-Dilke's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival. (1999) (800)
Mice lacking beta3 integrins are osteosclerotic because of dysfunctional osteoclasts. (2000) (727)
Bone marrow contributes to renal parenchymal turnover and regeneration (2001) (648)
Bone Marrow Contribution to Tumor-Associated Myofibroblasts and Fibroblasts (2004) (519)
Stimulation of tumor growth and angiogenesis by low concentrations of RGD-mimetic integrin inhibitors (2009) (445)
Use of the mouse aortic ring assay to study angiogenesis (2011) (438)
α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane (1997) (422)
Enhanced pathological angiogenesis in mice lacking β3 integrin or β3 and β5 integrins (2002) (400)
Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins. (2002) (328)
Efficient, inducible Cre‐recombinase activation in vascular endothelium (2008) (294)
Central roles of alpha5beta1 integrin and fibronectin in vascular development in mouse embryos and embryoid bodies. (2002) (284)
Multiple Organ Engraftment by Bone‐Marrow‐Derived Myofibroblasts and Fibroblasts in Bone‐Marrow‐Transplanted Mice (2003) (258)
Bone marrow derivation of pericryptal myofibroblasts in the mouse and human small intestine and colon (2002) (254)
Integrins: the keys to unlocking angiogenesis. (2008) (245)
Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. (2004) (226)
Novel Roles for α3β1 Integrin as a Regulator of Cytoskeletal Assembly and as a Trans-dominant Inhibitor of Integrin Receptor Function in Mouse Keratinocytes (1998) (221)
Activation of PPAR&bgr;/&dgr; Induces Endothelial Cell Proliferation and Angiogenesis (2007) (194)
Integrins in vascular development. (1999) (184)
Elevated Flk1 (Vascular Endothelial Growth Factor Receptor 2) Signaling Mediates Enhanced Angiogenesis in β3-Integrin–Deficient Mice (2004) (177)
A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning (2003) (168)
The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling (2015) (164)
Integrins in angiogenesis: multitalented molecules in a balancing act (2003) (160)
Interleukin-6 Stimulates Defective Angiogenesis. (2015) (157)
Focal adhesion kinase and tumour angiogenesis (2012) (143)
The diverse roles of integrins and their ligands in angiogenesis. (2002) (139)
Hemostasis in the Mouse (Mus musculus): A Review (1999) (137)
Requirements for Apoptotic Cell Contact in Regulation of Macrophage Responses1 (2006) (132)
Bone marrow cells engraft within the epidermis and proliferate in vivo with no evidence of cell fusion (2005) (131)
alphavbeta3 integrin and angiogenesis: a moody integrin in a changing environment. (2008) (127)
Endothelial-cell FAK targeting sensitizes tumours to DNA-damaging therapy (2014) (125)
Activation of PPARbeta/delta induces endothelial cell proliferation and angiogenesis. (2007) (120)
Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growth. (2005) (119)
Dual-action combination therapy enhances angiogenesis while reducing tumor growth and spread. (2015) (111)
The role of β3-integrins in tumor angiogenesis: context is everything. (2011) (109)
Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction (2019) (109)
Accelerated re-epithelialization in β3-integrin-deficient- mice is associated with enhanced TGF-β1 signaling (2005) (100)
αvβ3 Integrin Limits the Contribution of Neuropilin-1 to Vascular Endothelial Growth Factor-induced Angiogenesis* (2009) (94)
&bgr;3-Integrin Regulates Vascular Endothelial Growth Factor-A–Dependent Permeability (2004) (88)
Tumour angiogenesis is reduced in the Tc1 mouse model of Down Syndrome (2010) (86)
alpha3beta1 integrin-controlled Smad7 regulates reepithelialization during wound healing in mice. (2008) (85)
αvβ3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration (2010) (82)
Desmosomal proteins, including desmoglein 3, serve as novel negative markers for epidermal stem cell-containing population of keratinocytes (2003) (80)
Exploring Novel Methods for Modulating Tumor Blood Vessels in Cancer Treatment (2016) (78)
αvβ3 Integrin and tumour blood vessels-learning from the past to shape the future. (2016) (77)
Therapeutic expression of the platelet-specific integrin, αIIbβ3, in a murine model for Glanzmann thrombasthenia (2005) (76)
Cancer associated fibroblast FAK regulates malignant cell metabolism (2020) (72)
Accelerated re-epithelialization in beta3-integrin-deficient- mice is associated with enhanced TGF-beta1 signaling. (2005) (72)
Endothelial FAK is required for tumour angiogenesis (2010) (70)
CD36 or αvβ3 and αvβ5 Integrins Are Not Essential for MHC Class I Cross-Presentation of Cell-Associated Antigen by CD8α+ Murine Dendritic Cells1 (2002) (66)
Suppression of TGFβ and Angiogenesis by Type VII Collagen in Cutaneous SCC. (2016) (64)
Molecular Pathways: Endothelial Cell FAK—A Target for Cancer Treatment (2016) (62)
The role of cell adhesion pathways in angiogenesis. (2009) (61)
Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-VEGF. (2010) (58)
Primary mouse endothelial cell culture for assays of angiogenesis. (2006) (57)
Bone marrow-derived stromal cells express lineage-related messenger RNA species. (2006) (54)
Regulation of COX-2 mediated signaling by alpha3 type IV noncollagenous domain in tumor angiogenesis. (2007) (54)
Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis. (2003) (54)
Nanoparticle-mediated gene delivery to tumour neovasculature. (2003) (53)
Endothelial FAK is required for tumour angiogenesis (2016) (53)
Tumour angiogenesis is reduced in the Tc1 mouse model of Down’s syndrome (2010) (53)
Pancreatic stellate cells regulate blood vessel density in the stroma of pancreatic ductal adenocarcinoma (2016) (52)
FAK-heterozygous mice display enhanced tumour angiogenesis (2013) (44)
Therapeutic expression of the platelet-specific integrin, alphaIIbbeta3, in a murine model for Glanzmann thrombasthenia. (2005) (42)
Regulation of lymphatic-blood vessel separation by endothelial Rac1 (2009) (42)
Central Roles of &agr;5&bgr;1 Integrin and Fibronectin in Vascular Development in Mouse Embryos and Embryoid Bodies (2002) (41)
Genetic ablation of the alpha 6‐integrin subunit in Tie1Cre mice enhances tumour angiogenesis (2009) (39)
C-type natriuretic peptide co-ordinates cardiac structure and function (2019) (38)
Acute Depletion of Endothelial &bgr;3-Integrin Transiently Inhibits Tumor Growth and Angiogenesis in Mice (2014) (37)
Contribution of ADAMTS1 as a tumor suppressor gene in human breast carcinoma. Linking its tumor inhibitory properties to its proteolytic activity on nidogen‐1 and nidogen‐2 (2013) (35)
Gene Expression Analysis in Human Breast Cancer Associated Blood Vessels (2012) (34)
α3β1-integrin regulates hair follicle but not interfollicular morphogenesis in adult epidermis (2003) (32)
Tumor angiogenesis is differentially regulated by phosphorylation of endothelial cell focal adhesion kinase tyrosines-397 and -861. (2019) (32)
Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells (2020) (32)
Insights and Questions Arising from Studies of a Mouse Model of Glanzmann Thrombasthenia (1999) (31)
CD36 or alphavbeta3 and alphavbeta5 integrins are not essential for MHC class I cross-presentation of cell-associated antigen by CD8 alpha+ murine dendritic cells. (2002) (31)
Endothelial-Rac1 Is Not Required for Tumor Angiogenesis unless αvβ3-Integrin Is Absent (2010) (27)
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth (2020) (26)
avb3 integrin and angiogenesis: a moody integrin in a changing environment (2008) (26)
Tumour-associated endothelial-FAK correlated with molecular sub-type and prognostic factors in invasive breast cancer (2014) (22)
Overcoming the Lack of Oral Availability of Cyclic Hexapeptides: Design of a Selective and Orally Available Ligand for the Integrin αvβ3. (2017) (21)
Dual role of pericyte α6β1-integrin in tumour blood vessels (2017) (20)
Fascin 1 is dispensable for developmental and tumour angiogenesis (2013) (20)
Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion (2022) (17)
Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice (2012) (17)
Novel Pure αVβ3 Integrin Antagonists That Do Not Induce Receptor Extension, Prime the Receptor, or Enhance Angiogenesis at Low Concentrations (2019) (17)
Deficiency of bone marrow β3‐integrin enhances non‐functional neovascularization (2009) (17)
A HIF–LIMD1 negative feedback mechanism mitigates the pro‐tumorigenic effects of hypoxia (2018) (17)
Tumor Cell–Derived Angiopoietin-2 Promotes Metastasis in Melanoma (2020) (17)
Stromal Claudin14-Heterozygosity, but Not Deletion, Increases Tumour Blood Leakage without Affecting Tumour Growth (2013) (16)
Haematopoietic focal adhesion kinase deficiency alters haematopoietic homeostasis to drive tumour metastasis (2014) (16)
Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice (2021) (14)
Farnesyltransferase inhibitors target multiple endothelial cell functions in angiogenesis (2008) (12)
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway (2020) (11)
The Keys to Unlocking Angiogenesis (2008) (11)
Summary A crucial role for Fgfr 2-IIIb signalling in epidermal development and hair follicle patterning (11)
Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression (2020) (9)
Focal Adhesion Kinase (FAK) tyrosine 397E mutation restores the vascular leakage defect in endothelium‐specific FAK‐kinase dead mice (2017) (9)
“Splitting the matrix”: intussusceptive angiogenesis meets MT1‐MMP (2019) (9)
Tumour vascular leakage defect due to endothelium-targeted FAK-kinase dead mutation is abrogated by FAK-Y397E expression (2017) (8)
Generation of point‐mutant FAK knockin mice (2014) (8)
Improved Immunotherapy Efficacy by Vascular Modulation (2021) (7)
Integrins and angiogenesis: unlocking the route to gene therapy. (2003) (7)
A Promyelocytic Leukemia Protein–Thrombospondin-2 Axis and the Risk of Relapse in Neuroblastoma (2016) (7)
203 Hypoxia-inducible Factor-1 Regulates Matrix Metalloproteinase-14 Expression: Underlying Effects of Hypoxia and Statins (2014) (6)
Reply to: “Will integrin inhibitors have proangiogenic effects in the clinic?” (2009) (5)
Generation of genetically modified embryonic stem cells for the development of knockout mouse animal model systems. (2006) (4)
Primary mouse keratinocyte culture. (2002) (4)
Hepatocytes derived from bone marrow stem cells demonstrate polyploidisation (2001) (4)
Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment (2022) (4)
Repurposing an anti‐cancer agent for the treatment of hypertrophic heart disease (2019) (2)
Association of Low Tumor Endothelial Cell pY397–Focal Adhesion Kinase Expression With Survival in Patients With Neoadjuvant-Treated Locally Advanced Breast Cancer (2020) (2)
ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning (2022) (2)
Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth (2021) (2)
Tumour-associated endothelial-FAK correlated with molecular sub-type and prognostic factors in invasive breast cancer (2014) (1)
Measuring angiogenesis in mice. (2011) (1)
Abstract 4162: Interleukin–6 stimulates defective angiogenesis (2015) (1)
Improved Immunotherapy Efﬁcacy by Vascular Modulation (2021) (1)
Correction to: Phosphorylation of pericyte FAK‑Y861 affects tumour cell apoptosis and tumour blood vessel regression (2021) (1)
Primary tumor–derived systemic nANGPTL4 inhibits metastasis (2022) (1)
Microenvironmental Changes in DCIS: Myoepithelial Cells Change from Tumour Suppressor to Tumour Promoter. (2009) (0)
Cancer Cell Enhancing Chemotherapy Delivery and Efficacy drug (2015) (0)
Bone marrow contributes to tumour stroma (2004) (0)
Abstract 3479: Claudin-14: A novel regulator of angiogenesis (2011) (0)
Sticky science is skin deep: Cell Adhesion and Migration in Skin Disease (2001) (0)
6: Development of non-invasive imaging of integrin alpha-v-beta-6 (αvβ6)-positive lung cancers in advance of testing αvβ6-targeted therapies (2017) (0)
Interleukin-6 StimulatesDefectiveAngiogenesis (2015) (0)
P48 Integrins are required for synaptic transmission and development of the neuromuscular junction (2014) (0)
Stromal manipulation and Pancreatic cancer treatment (2014) (0)
Cancer associated fibroblast FAK regulates malignant cell metabolism (2020) (0)
Roles of alpha 3-integrin in development of the neuromuscular system (2012) (0)
Claudin-14 - A novel regulator of angiogenesis (2013) (0)
Abstract 517: Deficiency of FAK in the bone marrow compartment enhances tumour metastasis (2011) (0)
relapsing fever borreliosis Spirochete-platelet attachment and thrombocytopenia in murine (2013) (0)
Abstract 4848: Genetic profile of invasive breast cancer vasculature using laser capture microdissection (LCM) to capture vessels (2011) (0)
REGULATION OF VASCULAR DEVELOPMENT AND ANGIOGENESIS BY THE TRANSCRIPTION FACTOR ERG (2015) (0)
Abstract 3472: Endothelial FAK is required for tumor angiogenesis (2011) (0)
Skin type VII collagen acts as a tumor suppressor by regulating TGF and angiogenesis (2017) (0)
Novel roles for integrins in tumour angiogenesis (2006) (0)
Single cell transcriptome analyses reveal novel targets modulating cardiac neovascularisation by resident endothelial cells following myocardial infarction (2019) (0)
G.O.9 Integrins are required for synaptic transmission and development of the neuromuscular junction (2015) (0)
Edinburgh Research Explorer Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth (2020) (0)
Roles of alpha3-integrin in the development of the neuromuscular system (2012) (0)
OP9 Single Cell RNA-sequencing reveals novel targets with a potential role in vascular regeneration in the ischaemic adult heart (2020) (0)
Kairbaan Hodivala-Dilke (2016) (0)
INTEGRINS AND ANGIOGENESIS (2005) (0)
Diversity of desmoplakin expression in basal palm keratinocytes: A possible clue to the identification of epidermal stem cells (2002) (0)
Bone marrow stem cells make hepatocytes with replicative potential (2001) (0)
Dose- and schedule-dependent changes in vascular morphology after PI3K and PI3K/mTOR inhibition: in vitro vs. in vivo effects (2013) (0)
Abstract A31: Tumor stroma in the development of acquired cancer therapy resistance (2020) (0)
S1723 The Role of β3-Integrin On Bone Marrow-Derived Cells in Inflammatory Bowel Diseases (2008) (0)
Regulation of tumour progression and metastasis by Endothelial-FAK upon chemotherapy treatment (2020) (0)
Abstract 103: Single Cell Transcriptome Analyses Reveal Novel Targets for Therapeutic Neovascularisation by Resident Endothelial Cells in the Heart (2019) (0)
Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth (2020) (0)
106 Beta-3 integrin inhibition reduces inflammatory cytokine release but not anti-cancer activity of oncolytic adenovirus in ovarian cancer (2014) (0)
Abstract SY16-03: Dose matters and angiogenesis (2011) (0)
Integrins Are Not Essential for MHC Class I Cross-Presentation of Cell-Associated Antigen by CD8 Murine Dendritic Cells (2002) (0)
Blockade of integrin alpha-v-beta-6 (αvβ6) reduces the invasive potential of NSCLC (2018) (0)
Evaluating The Role Of b3‐Integrins In Angiogenesis (2006) (0)
A HIF-LIMD1 negative feedback mechanism drives the adaptive response to hypoxia and mitigates pro-tumorigenic hypoxic effects (2018) (0)
Development of non-invasive imaging of integrin alpha-v-beta-6 (alpha v beta 6)-positive lung cancers in advance of testing alpha v beta 6-targeted therapies (2017) (0)
Acute, but not constitutive, loss of endothelial β3-integrin inhibits tumour growth and angiogenesis (2013) (0)
Molecular Medicine HIF – LIMD 1 negative feedback mechanism (2018) (0)
P14 Roles of α3-integrin in development of the neuromuscular system (2012) (0)
Bone marrow derived cells contribute to a population of fibroblasts and myofibroblasts which engraft to multiple sites, including the gastrointestinal tract (2003) (0)
C-type natriuretic peptide coordinates cardiac structure and function * 1 (2019) (0)
P1.03-19 Antibody Blockade of Integrin Alpha-V-Beta-6 (avb6) as a Novel Treatment for NSCLC (2018) (0)

This paper list is powered by the following services:

Other Resources About Kairbaan Hodivala-Dilke

en.wikipedia.org

What Schools Are Affiliated With Kairbaan Hodivala-Dilke?

Kairbaan Hodivala-Dilke is affiliated with the following schools: