Kam W. Leong
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Kam W. Leongchemistry Degrees
Chemistry
#1608
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#2372
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Nanotechnology
#53
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#53
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Chemical Engineering
#114
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#127
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Kam W. Leongengineering Degrees
Engineering
#2471
World Rank
#3392
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Biomedical Engineering
#63
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#64
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Applied Physics
#321
World Rank
#333
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Chemistry Engineering
Kam W. Leong's Degrees
- PhD Chemical Engineering University of Pennsylvania
- Doctorate Medicine University of Pennsylvania
Why Is Kam W. Leong Influential?
(Suggest an Edit or Addition)Kam W. Leong's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Biomedical applications of polymer-composite materials: a review (2001) (1306)
- Scaffolding in tissue engineering: general approaches and tissue-specific considerations (2008) (1205)
- Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency. (2001) (1136)
- RNA-guided gene activation by CRISPR-Cas9-based transcription factors (2013) (1116)
- Oral gene delivery with chitosan–DNA nanoparticles generates immunologic protection in a murine model of peanut allergy (1999) (1083)
- Diverse Applications of Nanomedicine (2017) (825)
- Advanced materials and processing for drug delivery: the past and the future. (2013) (814)
- Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage. (2007) (712)
- Multifunctional nanorods for gene delivery (2003) (659)
- Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells. (2010) (642)
- Natural polymers for gene delivery and tissue engineering. (2006) (638)
- Nanopattern-induced changes in morphology and motility of smooth muscle cells. (2005) (628)
- Sustained release of proteins from electrospun biodegradable fibers. (2005) (548)
- DNA-polycation nanospheres as non-viral gene delivery vehicles. (1998) (510)
- Bioerodible polyanhydrides as drug-carrier matrices. I: Characterization, degradation, and release characteristics. (1985) (483)
- Electrohydrodynamics: A facile technique to fabricate drug delivery systems. (2009) (482)
- In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF). (2008) (470)
- The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation. (2008) (464)
- Chitosan nanoparticles for oral drug and gene delivery (2006) (413)
- Controlled release of heparin from poly(ε-caprolactone) electrospun fibers (2006) (390)
- Self-assembled supramolecular hydrogels formed by biodegradable PEO-PHB-PEO triblock copolymers and alpha-cyclodextrin for controlled drug delivery. (2006) (387)
- Simultaneous delivery of siRNA and paclitaxel via a "two-in-one" micelleplex promotes synergistic tumor suppression. (2011) (365)
- Polyethylenimine-grafted multiwalled carbon nanotubes for secure noncovalent immobilization and efficient delivery of DNA. (2005) (349)
- The effect of the degree of chitosan deacetylation on the efficiency of gene transfection. (2004) (340)
- CRISPR/Cas9-Based Genome Editing for Disease Modeling and Therapy: Challenges and Opportunities for Nonviral Delivery. (2017) (330)
- Characterization of topographical effects on macrophage behavior in a foreign body response model. (2010) (328)
- Ultrasound-enhanced polymer degradation and release of incorporated substances. (1989) (296)
- Significance of synthetic nanostructures in dictating cellular response. (2005) (292)
- The role of electrospinning in the emerging field of nanomedicine. (2006) (273)
- Polyphosphoesters in drug and gene delivery. (2003) (272)
- Biomaterials approach to expand and direct differentiation of stem cells. (2007) (268)
- Fabrication of controlled release biodegradable foams by phase separation. (1995) (262)
- Bioerodible polyanhydrides as drug-carrier matrices. II. Biocompatibility and chemical reactivity. (1986) (256)
- PEI-g-chitosan, a novel gene delivery system with transfection efficiency comparable to polyethylenimine in vitro and after liver administration in vivo. (2006) (255)
- Advanced drug delivery systems and artificial skin grafts for skin wound healing. (2019) (249)
- Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold. (2005) (244)
- Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells (2012) (241)
- Injectable drug-delivery systems based on supramolecular hydrogels formed by poly(ethylene oxide)s and alpha-cyclodextrin. (2003) (234)
- Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells. (2006) (229)
- In vitro and in vivo models for the study of oral delivery of nanoparticles. (2013) (225)
- Quantum dot-based theranostics. (2010) (222)
- Bioinspired Diselenide‐Bridged Mesoporous Silica Nanoparticles for Dual‐Responsive Protein Delivery (2018) (219)
- Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells. (2006) (218)
- A novel biodegradable gene carrier based on polyphosphoester. (2001) (216)
- Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function. (2011) (216)
- Rapid formation of multicellular spheroids in double-emulsion droplets with controllable microenvironment (2013) (207)
- Photocrosslinkable polysaccharides based on chondroitin sulfate. (2004) (206)
- Aligned core-shell nanofibers delivering bioactive proteins. (2006) (201)
- Interactions of phospholipid bilayer with chitosan: effect of molecular weight and pH. (2001) (200)
- Poly(α-hydroxy acids). Carriers for bone morphogenetic proteins (1996) (198)
- Aptamer nanomedicine for cancer therapeutics: barriers and potential for translation. (2015) (196)
- SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathways. (2014) (190)
- Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery (2010) (189)
- Microfluidic synthesis of multifunctional Janus particles for biomedical applications. (2012) (186)
- Gene transfer by DNA-gelatin nanospheres. (1999) (186)
- Preparation and Characterization of Polypseudorotaxanes Based on Block-Selected Inclusion Complexation between Poly(propylene oxide)-Poly(ethylene oxide)-Poly(propylene oxide) Triblock Copolymers and α-Cyclodextrin (2003) (181)
- Controlled release, biodegradable cytokine depots: a new approach in cancer vaccine design. (1993) (178)
- Mechanical properties of single electrospun drug-encapsulated nanofibres (2006) (178)
- Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits. (2003) (177)
- Targeted Epigenetic Remodeling of Endogenous Loci by CRISPR/Cas9-Based Transcriptional Activators Directly Converts Fibroblasts to Neuronal Cells. (2016) (176)
- Poly(L-lactic acid) foams with cell seeding and controlled-release capacity. (1996) (175)
- A materials-science perspective on tackling COVID-19 (2020) (175)
- Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide (2018) (172)
- A CRISPR/Cas9-Based System for Reprogramming Cell Lineage Specification (2014) (172)
- Biodegradable and photocrosslinkable polyphosphoester hydrogel. (2006) (171)
- Scalable fabrication of size-controlled chitosan nanoparticles for oral delivery of insulin. (2017) (170)
- Mast cell–derived particles deliver peripheral signals to remote lymph nodes (2009) (167)
- Surface charge critically affects tumor penetration and therapeutic efficacy of cancer nanomedicines (2016) (166)
- Peripheral nerve regeneration by microbraided poly(L-lactide-co-glycolide) biodegradable polymer fibers. (2004) (165)
- Engineering mesenchymal stem cells for regenerative medicine and drug delivery. (2015) (165)
- Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy. (2016) (164)
- Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET. (2006) (162)
- Emerging links between surface nanotechnology and endocytosis: impact on nonviral gene delivery. (2010) (159)
- A new nerve guide conduit material composed of a biodegradable poly(phosphoester). (2001) (154)
- Formation of Supramolecular Hydrogels Induced by Inclusion Complexation between Pluronics and α-Cyclodextrin (2001) (153)
- Quantitative comparison of intracellular unpacking kinetics of polyplexes by a model constructed from quantum dot-FRET. (2008) (152)
- Controlled gene delivery by DNA-gelatin nanospheres. (1998) (152)
- Guidance of stem cell fate on 2D patterned surfaces. (2012) (150)
- Designing zonal organization into tissue-engineered cartilage. (2006) (147)
- Biophysical Regulation of Cell Behavior—Cross Talk between Substrate Stiffness and Nanotopography (2017) (143)
- Inducing hepatic differentiation of human mesenchymal stem cells in pellet culture. (2006) (142)
- Sustained viral gene delivery through core-shell fibers. (2009) (141)
- Expansion of engrafting human hematopoietic stem/progenitor cells in three-dimensional scaffolds with surface-immobilized fibronectin. (2006) (137)
- Intranasal gene transfer by chitosan-DNA nanospheres protects BALB/c mice against acute respiratory syncytial virus infection. (2002) (137)
- Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers (2008) (136)
- Substrate topography shapes cell function (2009) (135)
- Dynamic Topographical Control of Mesenchymal Stem Cells by Culture on Responsive Poly(ϵ‐caprolactone) Surfaces (2011) (134)
- Immobilization of galactose ligands on acrylic acid graft-copolymerized poly(ethylene terephthalate) film and its application to hepatocyte culture. (2003) (134)
- Recent advances in nanoparticle-mediated siRNA delivery. (2014) (133)
- pH-sensitive polymeric nanoparticles for co-delivery of doxorubicin and curcumin to treat cancer via enhanced pro-apoptotic and anti-angiogenic activities. (2017) (132)
- Nanotopography as modulator of human mesenchymal stem cell function. (2012) (131)
- Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics. (2011) (130)
- Transcription Factors MYOCD, SRF, Mesp1 and SMARCD3 Enhance the Cardio-Inducing Effect of GATA4, TBX5, and MEF2C during Direct Cellular Reprogramming (2013) (130)
- Smart multifunctional drug delivery towards anticancer therapy harmonized in mesoporous nanoparticles. (2015) (129)
- Novel anisotropic engineered cardiac tissues: studies of electrical propagation. (2007) (129)
- Synthesis and Characterization of New Biodegradable Amphiphilic Poly(ethylene oxide)-b-poly[(R)-3-hydroxy butyrate]-b-poly(ethylene oxide) Triblock Copolymers (2003) (128)
- Transfection efficiency and transgene expression kinetics of mRNA delivered in naked and nanoparticle format. (2013) (126)
- Chitosan‐g‐PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions (2006) (126)
- Functional nanofiber scaffolds with different spacers modulate adhesion and expansion of cryopreserved umbilical cord blood hematopoietic stem/progenitor cells. (2007) (124)
- Hepatocyte encapsulation for enhanced cellular functions. (2000) (123)
- Biocompatibility of a biodegradable, controlled-release polymer in the rabbit brain. (1989) (123)
- Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage. (2013) (117)
- Microfluidic Hydrodynamic Focusing for Synthesis of Nanomaterials. (2016) (117)
- Polyphosphoester microspheres for sustained release of biologically active nerve growth factor. (2002) (115)
- Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance. (2005) (111)
- MicroRNA delivery for regenerative medicine. (2015) (111)
- Polymeric controlled drug delivery (1988) (109)
- Engineering Cell Membrane‐Based Nanotherapeutics to Target Inflammation (2019) (108)
- Enhanced gene expression in mouse muscle by sustained release of plasmid DNA using PPE-EA as a carrier (2002) (108)
- Chitosan nanoparticles containing plasmid DNA encoding house dust mite allergen, Der p 1 for oral vaccination in mice. (2003) (107)
- Viscoelastic behaviour of human mesenchymal stem cells (2008) (105)
- Controlled release from fibers of polyelectrolyte complexes. (2005) (105)
- Development of universal antidotes to control aptamer activity (2009) (104)
- Interaction of Human Mesenchymal Stem Cells With Disc Cells: Changes in Extracellular Matrix Biosynthesis (2006) (104)
- Nucleic acid-binding polymers as anti-inflammatory agents (2011) (101)
- Near-Infrared Fluorescent Nanoprobes for in Vivo Optical Imaging (2012) (101)
- New polyphosphoramidate with a spermidine side chain as a gene carrier. (2002) (101)
- Effects of nanoimprinted patterns in tissue-culture polystyrene on cell behavior. (2005) (99)
- Engineered materials for in vivo delivery of genome-editing machinery (2019) (98)
- Nucleic acid scavengers inhibit thrombosis without increasing bleeding (2012) (98)
- Polyanhydrides for controlled release of bioactive agents. (1986) (98)
- Walking the line: The fate of nanomaterials at biological barriers. (2018) (97)
- Transport of chitosan-DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes. (2010) (94)
- Multi-layered microcapsules for cell encapsulation. (2002) (94)
- Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium. (2008) (93)
- Controlled Local Delivery of Interleukin-2 by Biodegradable Polymers Protects Animals from Experimental Brain Tumors and Liver Tumors (2001) (93)
- Surface-immobilization of adhesion peptides on substrate for ex vivo expansion of cryopreserved umbilical cord blood CD34+ cells. (2006) (92)
- Cell-laden microfluidic microgels for tissue regeneration. (2016) (92)
- Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity (2014) (91)
- Phase II Randomized Trial of Autologous Formalin-Fixed Tumor Vaccine for Postsurgical Recurrence of Hepatocellular Carcinoma (2004) (91)
- In vitro gene delivery using polyamidoamine dendrimers with a trimesyl core. (2005) (90)
- Biomimetic Diselenide‐Bridged Mesoporous Organosilica Nanoparticles as an X‐ray‐Responsive Biodegradable Carrier for Chemo‐Immunotherapy (2020) (90)
- Synthesis of polyanhydrides: melt-polycondensation, dehydrochlorination, and dehydrative coupling (1987) (90)
- Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes. (2012) (89)
- Galactosylated ternary DNA/polyphosphoramidate nanoparticles mediate high gene transfection efficiency in hepatocytes. (2005) (88)
- A programmable microenvironment for cellular studies via microfluidics-generated double emulsions. (2013) (86)
- Gene transfer to hemophilia A mice via oral delivery of FVIII-chitosan nanoparticles. (2008) (85)
- Controlled release of heparin from poly(epsilon-caprolactone) electrospun fibers. (2006) (84)
- Controlled delivery of antigens and adjuvants in vaccine development. (1996) (83)
- Droplet microfluidics platform for highly sensitive and quantitative detection of malaria-causing Plasmodium parasites based on enzyme activity measurement. (2012) (82)
- In Vitro Chondrogenesis of Mesenchymal Stem Cells in Recombinant Silk-elastinlike Hydrogels (2008) (81)
- Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance. (2003) (80)
- Scaffold-free, Human Mesenchymal Stem Cell-Based Tissue Engineered Blood Vessels (2015) (79)
- Evaluation of polyphosphates and polyphosphonates as degradable biomaterials. (1991) (79)
- Micellization phenomena of biodegradable amphiphilic triblock copolymers consisting of poly(beta-hydroxyalkanoic acid) and poly(ethylene oxide). (2005) (78)
- Co-culture of umbilical cord blood CD34+ cells with human mesenchymal stem cells. (2006) (78)
- Hyperbranched poly(amino ester)s with different terminal amine groups for DNA delivery. (2006) (78)
- Deformation of stem cell nuclei by nanotopographical cues. (2010) (78)
- The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons. (2014) (78)
- Spatial metagenomic characterization of microbial biogeography in the gut (2019) (77)
- Implantation of Mouse Embryonic Stem Cell-Derived Cardiac Progenitor Cells Preserves Function of Infarcted Murine Hearts (2010) (76)
- Poly(D,L-lactide-co-ethyl ethylene phosphate)s as new drug carriers. (2003) (76)
- Effects of topographical and mechanical property alterations induced by oxygen plasma modification on stem cell behavior. (2012) (76)
- Light: A Magical Tool for Controlled Drug Delivery (2020) (75)
- Biodegradable polyphosphoester micelles for gene delivery. (2004) (75)
- Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression (2004) (73)
- Nanoscale surfacing for regenerative medicine. (2010) (72)
- Efficient One-Step Production of Microencapsulated Hepatocyte Spheroids with Enhanced Functions. (2016) (72)
- Polyanhydrides as drug delivery systems (1990) (72)
- Engineering strategies to enhance nanoparticle-mediated oral delivery (2008) (70)
- Fabrication of poly(phosphoester) nerve guides by immersion precipitation and the control of porosity. (2001) (70)
- Repeated intrathecal administration of plasmid DNA complexed with polyethylene glycol-grafted polyethylenimine led to prolonged transgene expression in the spinal cord (2003) (70)
- Sustained delivery of siRNA/mesoporous silica nanoparticle complexes from nanofiber scaffolds for long-term gene silencing. (2018) (69)
- Proliferation and differentiation of human mesenchymal stem cell encapsulated in polyelectrolyte complexation fibrous scaffold. (2006) (69)
- Mechanism of fiber formation by interfacial polyelectrolyte complexation (2004) (69)
- Hepatic differentiation potential of commercially available human mesenchymal stem cells. (2006) (68)
- Musculoskeletal Differentiation of Cells Derived from Human Embryonic Germ Cells (2005) (68)
- Uniform Core–Shell Nanoparticles with Thiolated Hyaluronic Acid Coating to Enhance Oral Delivery of Insulin (2018) (67)
- Mechanism of oral tolerance induction to therapeutic proteins. (2013) (67)
- High density of immobilized galactose ligand enhances hepatocyte attachment and function. (2003) (66)
- HPV Oncogene Manipulation Using Nonvirally Delivered CRISPR/Cas9 or Natronobacterium gregoryi Argonaute (2018) (66)
- Thermally responsive polymeric micellar nanoparticles self-assembled from cholesteryl end-capped random poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide): synthesis, temperature-sensitivity, and morphologies. (2003) (66)
- Water-soluble and nonionic polyphosphoester: synthesis, degradation, biocompatibility and enhancement of gene expression in mouse muscle. (2004) (66)
- Induced Pluripotent Stem Cell-Derived Cardiac Progenitors Differentiate to Cardiomyocytes and Form Biosynthetic Tissues (2013) (65)
- Transgene expression in the brain stem effected by intramuscular injection of polyethylenimine/DNA complexes. (2001) (65)
- Dynamic and static light scattering studies on self-aggregation behavior of biodegradable amphiphilic poly(ethylene oxide)-poly[(R)-3-hydroxybutyrate]-poly(ethylene oxide) triblock copolymers in aqueous solution. (2006) (64)
- Functional Recovery of Contused Spinal Cord in Rat with the Injection of Optimal‐Dosed Cerium Oxide Nanoparticles (2017) (64)
- Nonviral Direct Conversion of Primary Mouse Embryonic Fibroblasts to Neuronal Cells (2012) (63)
- Simultaneous Non-invasive Analysis of DNA Condensation and Stability by Two-step QD-FRET. (2009) (63)
- Directed Assembly of Multisegment Au/Pt/Au Nanowires (2004) (62)
- Engineering of a sugar-derivatized porous network for hepatocyte culture. (1996) (61)
- Polyphosphoramidate gene carriers: effect of charge group on gene transfer efficiency (2004) (61)
- Block-selected molecular recognition and formation of polypseudorotaxanes between poly(propylene oxide)-poly(ethylene oxide)-poly(propylene oxide) triblock copolymers and alpha-cyclodextrin. (2004) (60)
- Tuning physical properties of nanocomplexes through microfluidics-assisted confinement. (2011) (60)
- Microcapsules with improved mechanical stability for hepatocyte culture. (2003) (59)
- Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery (2006) (58)
- Poly(Ethylene Glycol) Hydrogel Scaffolds Containing Cell-Adhesive and Protease-Sensitive Peptides Support Microvessel Formation by Endothelial Progenitor Cells (2016) (58)
- Coculture of mesenchymal stem cells and respiratory epithelial cells to engineer a human composite respiratory mucosa. (2004) (58)
- Nonviral gene delivery from nonwoven fibrous scaffolds fabricated by interfacial complexation of polyelectrolytes. (2006) (58)
- Engineering of a microfluidic cell culture platform embedded with nanoscale features. (2011) (58)
- Differentiation of Mouse Induced Pluripotent Stem Cells (iPSCs) into Nucleus Pulposus-Like Cells In Vitro (2013) (57)
- Efficacy of engineered FVIII-producing skeletal muscle enhanced by growth factor-releasing co-axial electrospun fibers. (2011) (57)
- A finite element model for predicting the distribution of drugs delivered intracranially to the brain. (1997) (56)
- Messenger RNA (mRNA) nanoparticle tumour vaccination. (2014) (56)
- Plant-based oral tolerance to hemophilia therapy employs a complex immune regulatory response including LAP+CD4+ T cells. (2015) (56)
- Codelivery of CRISPR-Cas9 and chlorin e6 for spatially controlled tumor-specific gene editing with synergistic drug effects (2020) (55)
- Nucleic acid-based nanoengineering: novel structures for biomedical applications (2011) (54)
- Efficacy of paclitaxel released from bio-adhesive polymer microspheres on model superficial bladder cancer. (2004) (54)
- Synthesis of Fluorosurfactants for Emulsion-Based Biological Applications (2014) (53)
- Fibronectin immobilized by covalent conjugation or physical adsorption shows different bioactivity on aminated-PET (2007) (53)
- Glaucoma filtration surgery in monkeys using 5-fluorouridine in polyanhydride disks. (1990) (53)
- The use of bioerodible polymers and 5-fluorouracil in glaucoma filtration surgery. (1988) (53)
- The NIH Somatic Cell Genome Editing program (2021) (53)
- Encapsulation of biologics in self-assembled fibers as biostructural units for tissue engineering. (2004) (52)
- Proliferation and differentiation of human embryonic germ cell derivatives in bioactive polymeric fibrous scaffold (2005) (52)
- Preparation and Characterization of Inclusion Complexes of Biodegradable Amphiphilic Poly(ethylene oxide)−Poly[(R)-3-hydroxybutyrate]−Poly(ethylene oxide) Triblock Copolymers with Cyclodextrins (2003) (52)
- Cytotoxic effects of Mn(III) N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate (2011) (52)
- Highly Aligned Nanofibrous Scaffold Derived from Decellularized Human Fibroblasts (2014) (52)
- Sustained release of exendin‐4 from tannic acid/Fe (III) nanoparticles prolongs blood glycemic control in a mouse model of type II diabetes (2019) (51)
- Adhesion contact dynamics of HepG2 cells on galactose-immobilized substrates. (2003) (51)
- Materials innovation for co-delivery of diverse therapeutic cargos. (2013) (51)
- Evaluation of hyperbranched poly(amino ester)s of amine constitutions similar to polyethylenimine for DNA delivery. (2005) (51)
- Interfacial polycondensation and characterization of polyphosphates and polyphosphonates (1991) (51)
- Detection of single enzymatic events in rare or single cells using microfluidics. (2011) (50)
- Folding artificial mucosa with cell-laden hydrogels guided by mechanics models (2018) (50)
- 3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine (2015) (49)
- Glaucoma filtration surgery in rabbits using bioerodible polymers and 5-fluorouracil. (1987) (48)
- Mitigation of hypertrophic scar contraction via an elastomeric biodegradable scaffold. (2015) (48)
- Poly(ethylene imine)-g-chitosan using EX-810 as a spacer for nonviral gene delivery vectors. (2009) (47)
- Use of bioerodible polymers impregnated with mitomycin in glaucoma filtration surgery in rabbits. (1991) (47)
- Effects of MIP-1α, MIP-3α, and MIP-3β on the Induction of HIV Gag-specific Immune Response with DNA Vaccines. (2007) (47)
- Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing (2013) (47)
- Small Intestinal Submucosa as a Potential Bioscaffold for Intervertebral Disc Regeneration (2006) (47)
- Potency of a Scalable Nanoparticulate Subunit Vaccine. (2018) (47)
- Endosomal signaling of delta opioid receptors is an endogenous mechanism and therapeutic target for relief from inflammatory pain (2020) (46)
- Engineered Mesenchymal Stem Cell/Nanomedicine Spheroid as an Active Drug Delivery Platform for Combinational Glioblastoma Therapy. (2019) (46)
- Three-dimensional culture of rabbit nucleus pulposus cells in collagen microspheres. (2011) (46)
- An implantable blood clot–based immune niche for enhanced cancer vaccination (2020) (46)
- A 3D Electroactive Polypyrrole-Collagen Fibrous Scaffold for Tissue Engineering (2011) (46)
- Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation. (2004) (46)
- Three-dimensional hydrodynamic focusing method for polyplex synthesis. (2014) (45)
- Ultrasonically controlled polymeric drug delivery (1988) (44)
- Scalable production of core-shell nanoparticles by flash nanocomplexation to enhance mucosal transport for oral delivery of insulin. (2018) (44)
- MR imaging of biodegradable polymeric microparticles: A potential method of monitoring local drug delivery (2005) (44)
- Use of Cartilage Derived From Murine Induced Pluripotent Stem Cells for Osteoarthritis Drug Screening (2014) (44)
- Dual‐Sensitive Micellar Nanoparticles Regulate DNA Unpacking and Enhance Gene‐Delivery Efficiency (2010) (43)
- Nucleic acid scavenging microfiber mesh inhibits trauma-induced inflammation and thrombosis. (2017) (43)
- Fibroblast and hepatocyte behavior on synthetic polymer surfaces. (1991) (43)
- Protein-reactive nanofibrils decorated with cartilage-derived decellularized extracellular matrix for osteochondral defects. (2020) (43)
- Shape-Controlled Synthesis of Hybrid Nanomaterials via Three-Dimensional Hydrodynamic Focusing (2014) (43)
- Label-free, high-throughput measurements of dynamic changes in cell nuclei using angle-resolved low coherence interferometry. (2008) (43)
- Nanoparticle-mediated inhibition of survivin to overcome drug resistance in cancer therapy. (2016) (43)
- Improvements in solubility and stability of thalidomide upon complexation with hydroxypropyl-beta-cyclodextrin. (1992) (42)
- A Nonlinear Hyperelastic Mixture Theory Model for Anisotropy, Transport, and Swelling of Annulus Fibrosus (2004) (42)
- In vitro and in vivo studies of subcutaneous hydromorphone implants designed for the treatment of cancer pain (1996) (41)
- Revascularization and limb salvage following critical limb ischemia by nanoceria-induced Ref-1/APE1-dependent angiogenesis. (2020) (40)
- Integration of drug, protein, and gene delivery systems with regenerative medicine (2015) (40)
- Tuned Cationic Dendronized Polymer: Molecular Scavenger for Rheumatoid Arthritis Treatment. (2019) (40)
- High-throughput screening of microscale pitted substrate topographies for enhanced nonviral transfection efficiency in primary human fibroblasts. (2011) (39)
- Advances in microphysiological blood-brain barrier (BBB) models towards drug delivery. (2020) (39)
- Low oxygen tension and synthetic nanogratings improve the uniformity and stemness of human mesenchymal stem cell layer. (2010) (39)
- Treatment of severe sepsis with nanoparticulate cell-free DNA scavengers (2020) (39)
- Evaluation of collagen and methylated collagen as gene carriers. (2004) (39)
- Glaucoma filtration surgery in nonhuman primates using taxol and etoposide in polyanhydride carriers. (1993) (38)
- Extra- and intra-cellular fate of nanocarriers under dynamic interactions with biology (2017) (38)
- Controlled release from poly(phosphoester) matrices (1995) (38)
- Size-controlled lipid nanoparticle production using turbulent mixing to enhance oral DNA delivery. (2018) (37)
- Anti-infective biomaterials with surface-decorated tachyplesin I. (2018) (37)
- In vitro release of vascular endothelial growth factor from gadolinium‐doped biodegradable microspheres (2004) (37)
- Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters. (2003) (37)
- Deterministic transfection drives efficient nonviral reprogramming and uncovers reprogramming barriers. (2016) (37)
- Microfluidic Isolation and Enrichment of Nanoparticles. (2020) (36)
- Biomaterials control of pluripotent stem cell fate for regenerative therapy (2016) (36)
- Comparative study of nanoparticle-mediated transfection in different GI epithelium co-culture models. (2012) (36)
- Microfluidic Preparation of Polymer-Nucleic Acid Nanocomplexes Improves Nonviral Gene Transfer (2013) (36)
- A multifunctional mesoporous silica-gold nanocluster hybrid platform for selective breast cancer cell detection using a catalytic amplification-based colorimetric assay. (2019) (36)
- Controlled release of macromolecules: Biological studies☆ (1985) (36)
- Tissue compatibility of interfacial polyelectrolyte complexation fibrous scaffold: evaluation of blood compatibility and biocompatibility. (2006) (35)
- Stimuli-responsive hydrogel based on poly(propylene phosphate) (2004) (35)
- Chitosan-Induced Perturbation of Dipalmitoyl-sn-glycero-3-phosphocholine Membrane Bilayer (2001) (35)
- Inclusion complexation and formation of polypseudorotaxanes between poly[(ethylene oxide)-ran-(propylene oxide)] and cyclodextrins (2001) (35)
- Polyanhydride microsphere formulation by solvent extraction. (1988) (35)
- Engineered biomaterials for cancer immunotherapy (2020) (34)
- A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury. (2021) (34)
- Coacervate microspheres as carriers of recombinant adenoviruses (1999) (34)
- Nonendocytic Delivery of Lipoplex Nanoparticles into Living Cells Using Nanochannel Electroporation (2014) (34)
- Dynamics of smooth muscle cell deadhesion from thermosensitive hydroxybutyl chitosan. (2007) (34)
- Galactosylated poly(vinylidene difluoride) hollow fiber bioreactor for hepatocyte culture. (2005) (33)
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- Polymeric Scaffolds for Tissue Engineering (2003) (6)
- Protein Delivery: Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles for Dual-Responsive Protein Delivery (Adv. Mater. 29/2018) (2018) (6)
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- Controlled Drug Delivery to the Joints by Enzymatically Degradable Microspheres (1993) (5)
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- Biopolymer—DNA Nanospheres (1999) (4)
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- Poly(Phosphoesters) as Bioabsorbable Osteosynthetic Materials (1991) (2)
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- Abstract 34: A Novel Immune Competent Murine Hypertrophic Scar Contracture Model A Tool to Elucidate Disease Mechanism and Develop New Therapies (2014) (1)
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- Poly(Ethylene Glycol) Hydrogel Scaffolds Containing Cell-Adhesive and Protease-Sensitive Peptides Support Microvessel Formation by Endothelial Progenitor Cells (2015) (0)
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- Cellular Response to Continuous Nanostructures (2010) (0)
- 171. PEG-b-PPA/DNA Micelles for Liver Targeted-Gene Delivery (2006) (0)
- Abstract 124: Mitigation Of Hypertrophic Scar Contraction And Stiffening Via An Elastomeric Biodegradable Scaffold (2015) (0)
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What Schools Are Affiliated With Kam W. Leong?
Kam W. Leong is affiliated with the following schools:
- Johns Hopkins University
- South China University of Technology
- University of California, San Francisco
- Columbia University
- King Abdulaziz University
- Duke University
- University of Pennsylvania
- Dankook University
- Sun Yat-sen University
- Wuhan University
- University of California, Santa Barbara
- National University of Singapore
