Kamal Badr
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Professor of Medicine and Chairman of the Department of Internal Medicine at the American University of Beirut
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Why Is Kamal Badr Influential?
(Suggest an Edit or Addition)According to Wikipedia, Dr. Kamal Badr is a Lebanese-American physician and scientist who has been Professor of Medicine and Chair of the Department of Internal Medicine at the American University of Beirut from July 2000 to late 2006. He then was named Founding Dean of the Lebanese American University’s new medical school, a position he held until September 1, 2010. He returned to the American University of Beirut in October 2010, where he is Associate Dean for Medical Education.
Kamal Badr's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism. (1990) (1834)
- Glomerular actions of a free radical-generated novel prostaglandin, 8-epi-prostaglandin F2 alpha, in the rat. Evidence for interaction with thromboxane A2 receptors. (1992) (507)
- Mesangial cell, glomerular and renal vascular responses to endothelin in the rat kidney. Elucidation of signal transduction pathways. (1989) (424)
- Plasma endothelin immunoreactivity in liver disease and the hepatorenal syndrome. (1992) (336)
- Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation. (1992) (322)
- Free radical-induced generation of isoprostanes in vivo. Evidence for the formation of D-ring and E-ring isoprostanes. (1994) (303)
- Induction of 15-lipoxygenase by interleukin-13 in human blood monocytes. (1994) (253)
- Role for intrarenal mechanisms in the impaired salt excretion of experimental nephrotic syndrome. (1983) (249)
- Evidence for the existence of F2-isoprostane receptors on rat vascular smooth muscle cells. (1993) (231)
- Prerenal failure: a deleterious shift from renal compensation to decompensation. (1988) (192)
- Biological actions and pathophysiologic significance of endothelin in the kidney. (1991) (178)
- Roles for thromboxane A2 and leukotrienes in endotoxin-induced acute renal failure. (1986) (169)
- Free-radical-generated F2-isoprostane stimulates cell proliferation and endothelin-1 expression on endothelial cells. (1999) (165)
- Evidence that the F2-isoprostane, 8-epi-prostaglandin F2α, is formed in vivo (1994) (156)
- Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis. (1999) (154)
- Lipoxin A4 antagonizes cellular and in vivo actions of leukotriene D4 in rat glomerular mesangial cells: evidence for competition at a common receptor. (1989) (154)
- Renal and Systemic Hemodynamic Responses to Intravenous Infusion of Leukotriene C4 in the Rat (1984) (152)
- Continuous stretch-relaxation in culture alters rat mesangial cell morphology, growth characteristics, and metabolic activity. (1992) (142)
- Overexpression of 15-lipoxygenase-1 in PC-3 human prostate cancer cells increases tumorigenesis. (2001) (137)
- Complement activation retards resolution of acute ischemic renal failure in the rat. (1991) (122)
- Mechanical stretch/relaxation of cultured rat mesangial cells induces protooncogenes and cyclooxygenase. (1994) (118)
- Two distinct pathways in the down-regulation of type-1 angiotension II receptor gene in rat glomerular mesangial cells. (1992) (114)
- Evidence for glomerular actions of epidermal growth factor in the rat. (1988) (113)
- F(2)-isoprostanes mediate high glucose-induced TGF-beta synthesis and glomerular proteinuria in experimental type I diabetes. (2000) (111)
- Concordant induction of 15-lipoxygenase-1 and mutant p53 expression in human prostate adenocarcinoma: correlation with Gleason staging. (2000) (109)
- Marked overproduction of non-cyclooxygenase derived prostanoids (F2-isoprostanes) in the hepatorenal syndrome. (1993) (100)
- Evidence for the distinct nature of F2-isoprostane receptors from those of thromboxane A2. (1997) (90)
- Cytochrome P-450 arachidonate metabolites in rat kidney: characterization and hemodynamic responses. (1990) (88)
- Sepsis-associated renal vasoconstriction: potential targets for future therapy. (1992) (83)
- Identification of two types of specific endothelin receptors in rat mesangial cell. (1989) (78)
- Vascular smooth muscle actions and receptor interactions of 8-iso-prostaglandin E2, an E2-isoprostane. (1993) (76)
- Co-regulated expression of glomerular 12/15-lipoxygenase and interleukin-4 mRNAs in rat nephrotoxic nephritis. (1994) (75)
- Preservation of the glomerular capillary ultrafiltration coefficient during rat nephrotoxic serum nephritis by a specific leukotriene D4 receptor antagonist. (1988) (68)
- Glomerular stereospecific synthesis and hemodynamic actions of 8,9-epoxyeicosatrienoic acid in rat kidney. (1991) (67)
- Effects of leukotriene D4 on glomerular dynamics in the rat. (1987) (63)
- High and low affinity binding sites for endothelin on cultured rat glomerular mesangial cells. (1989) (63)
- Dietary supplementation with L-arginine ameliorates glomerular hypertension in rats with subtotal nephrectomy. (1994) (59)
- Stimulatory Effect of 8‐Epi-PGF2α, An F2-Isoprostane, on Endothelin‐1 Release (1995) (59)
- Glomerular responses to platelet-activating factor in the rat: role of thromboxane A2. (1989) (50)
- The action of lipoxin-A on glomerular microcirculatory dynamics in the rat. (1987) (50)
- Endotoxin and renal function: perspectives to the understanding of septic acute renal failure and toxic shock. (1999) (49)
- Modulation of COX‐2 expression by statins in human monocytic cells (2007) (49)
- Cytokine imbalance in acute coronary syndrome. (2004) (48)
- Consequences of acute nitric oxide synthesis inhibition in experimental glomerulonephritis. (1994) (46)
- Effects of mutant p53 expression on human 15-lipoxygenase-promoter activity and murine 12/15-lipoxygenase gene expression: evidence that 15-lipoxygenase is a mutator gene. (1999) (46)
- Renal hemodynamic actions of lipoxins in rats: a comparative physiological study. (1992) (46)
- Functional significance of leukotriene B4 in normal and glomerulonephritic kidneys. (1991) (45)
- Fifteen-S-hydroxyeicosatetraenoic acid (15-S-HETE) specifically antagonizes the chemotactic action and glomerular synthesis of leukotriene B4 in the rat. (1992) (45)
- Isoprostanes and the kidney. (2005) (43)
- Characterization of a large Lebanese family segregating IgA nephropathy. (2007) (43)
- Predominant functional roles for thromboxane A2 and prostaglandin E2 during late nephrotoxic serum glomerulonephritis in the rat. (1990) (42)
- A series of prostaglandin F 2-like compounds are produced in vivo in humans by a non-cyclooxygenase , free radical-catalyzed mechanism ( eicosanoids / oxidative stress / lipid peroxidation / mass spectrometry ) (42)
- Crowd-funded micro-grants for genomics and "big data": an actionable idea connecting small (artisan) science, infrastructure science, and citizen philanthropy. (2013) (41)
- Role for Doppler ultrasound in the assessment of renal circulation: effects of dopamine and dobutamine on renal hemodynamics in humans. (1995) (41)
- Mechanisms of amphotericin B-induced reduction of the glomerular filtration rate: a micropuncture study. (1990) (39)
- The long-term impact of team-based learning on medical students’ team performance scores and on their peer evaluation scores (2016) (38)
- Stimulatory effect of 8-Epi-PGF2 alpha, an F2-isoprostane, on endothelin-1 release. (1995) (37)
- Leukotriene D4 is a mediator of proteinuria and glomerular hemodynamic abnormalities in passive Heymann nephritis. (1993) (36)
- Contrasting effects of proinflammatory and T-helper lymphocyte subset-2 cytokines on the 5-lipoxygenase pathway in monocytes. (1997) (35)
- Five-lipoxygenase products in glomerular immune injury. (1992) (34)
- Human 15-Lipoxygenase gene promoter: analysis and identification of DNA binding sites for IL-13-induced regulatory factors in monocytes (1998) (34)
- Endothelins 1 and 3: Potent cholestatic agents secreted and excreted by the liver that interact with cyclosporine (1993) (32)
- Legislative, educational, policy and other interventions targeting physicians’ interaction with pharmaceutical companies: a systematic review (2014) (32)
- Molecular and functional evidence for the distinct nature of F2-isoprostane receptors from those of thromboxane A2. (1995) (32)
- Role of endothelin in the development of Dahl hypertension. (1991) (30)
- 15-Lipoxygenase products as leukotriene antagonists: therapeutic potential in glomerulonephritis. (1992) (29)
- Glomerulonephritis: roles for lipoxygenase pathways in pathophysiology and therapy. (1997) (27)
- Evidence that the F2-isoprostane, 8-epi-prostaglandin F2 alpha, is formed in vivo. (1994) (26)
- Hormonal influences on glomerular filtration (1980) (25)
- Mediation of renal vascular effects of epidermal growth factor by arachidonate metabolites (1990) (23)
- 15-lipoxygenase-1 overexpression in prostate adenocarcinoma. (2002) (23)
- Role of leukotrienes and lipoxygenases in glomerular injury. (1995) (22)
- Angiotensin II receptors: cloning and regulation. (1993) (22)
- A 5-year survey of biopsy proven kidney diseases in Lebanon: significant variation in prevalence of primary glomerular diseases by age, population structure and consanguinity. (2010) (22)
- Essential fatty acid deficiency normalizes function and histology in rat nephrotoxic nephritis. (1992) (22)
- Leukotriene D4 binding and signal transduction in rat glomerular mesangial cells. (1989) (21)
- THE EFFECTS OF SURGERY AND ACUTE REJECTION ON GLOMERULAR HEMODYNAMICS IN THE TRANSPLANTED RAT KIDNEY (1993) (21)
- Maintenance of endothelin-induced renal arteriolar constriction in rats is cyclooxygenase dependent. (1993) (20)
- Molecular pharmacology of isoprostanes in vascular smooth muscle. (2004) (19)
- A role for atrial natriuretic peptide in endothelin-induced natriuresis. (1991) (17)
- Expression of recombinant rat interleukin-13 (IL-13) and generation of a neutralizing rat IL-13 antiserum. (1997) (16)
- Reciprocal Regulation of LTA4 Hydrolase Expression in Human Monocytes by γ-Interferon and Interleukins 4 and 13: Potential Relevance to Leukotriene Regulation in Glomerular Disease (2000) (16)
- Lipoxygenase Products in Normal and Diseased Glomeruli a (1994) (15)
- Studies on the glomerular microcirculatory actions of manidipine and its modulation of the systemic and renal effects of endothelin. (1993) (15)
- Recovery of prostaglandin synthesis in rat glomerular mesangial cells after aspirin inhibition: induction of cyclooxygenase activity by serum and epidermal growth factor. (1990) (14)
- The effect of thromboxane A2 receptor antagonism on amphotericin B-induced renal vasoconstriction in the rat. (1993) (14)
- Inhibition of 5-lipoxygenase activating protein decreases proteinuria in diabetic rats. (2003) (14)
- 15-Lipoxygenase in Glomerular Inflammation (2000) (14)
- MK-591 acutely restores glomerular size selectivity and reduces proteinuria in human glomerulonephritis. (1999) (13)
- Measuring filtration function in clinical practice (2006) (13)
- Endothelin in kidney disease. (1994) (13)
- Novel approaches to treatment of glomerulonephritis. (1998) (11)
- Effect of salt intake on beat‐to‐beat blood pressure nonlinear dynamics and entropy in salt‐sensitive versus salt‐protected rats (2016) (11)
- Tachyphylaxis of human forearm vascular responses does not occur rapidly after exposure to isoproterenol. (1995) (11)
- Increased 5-lipoxygenase activating protein in immune-mediated experimental nephritis. (2003) (11)
- Effects of chronic prolactin administration on renal hemodynamics in the rat. (1985) (11)
- Formation of unique biologically active prostaglandins in vivo by a non-cyclooxygenase free radical catalyzed mechanism. (1991) (11)
- Inflammation in the cardiovascular system: here, there and everywhere. (2004) (10)
- Induction of renal arachidonate cytochrome P-450 epoxygenase after uninephrectomy: counterregulation of hyperfiltration. (1993) (9)
- Mechanism of induction of prostaglandin E2 production by endothelin 1 in cultured rat mesangial cells. (1996) (9)
- Regionalizing healthcare: a vision for transforming Lebanon into a regional academic hub (2010) (8)
- KU 70/80 lupus autoantigen is the transcription factor induced by interleukins (IL)-13 and -4 leading to induction of 15-lipoxygenase (15-LO) in human cells. (2002) (8)
- Willingness of Lebanese physicians in the United States to relocate to Lebanon (2012) (7)
- Lipoxygenases as therapeutic targets in the acute and subacute phases of glomerular immune injury. (1996) (7)
- Novel mediators of sepsis-associated renal failure. (1994) (7)
- The association of urinary metabolites of polycyclic aromatic hydrocarbons with obstructive coronary artery disease: A red alert for action. (2020) (7)
- Reversing the brain drain: a Lebanese model (2012) (7)
- Arachidonic acid metabolites in glomerular immune injury. (1991) (7)
- The public cost of 3 statins for primary prevention of cardiovascular events in 7 Middle East countries: not all of them can afford it. (2012) (7)
- Arachidonate cyclo-oxygenase and lipoxygenase products in the mediation of glomerular immune injury. (1991) (6)
- Circulating endothelin-1 is not increased in severe preeclampsia (1992) (6)
- The amino acid-induced alteration in renal hemodynamics is glucagon independent. (1991) (6)
- Arachidonate and renal function. (1993) (5)
- Physician assessment of stroke risk in hypertensive patients in the Middle East and Africa: results of the action survey. (2007) (5)
- KU lupus autoantigen is the transcription factor induced by interleukins (IL)-13 and IL-4 leading to induction of 15-lipoxygenase-1 (15-LO) in human cells (1999) (4)
- Regulation of MAP-kinase activation by 8-iso-prostaglandin F2a in cultured rat aortic smooth muscle cells. (1997) (4)
- Cell-cell interactions in the regulation of glomerular inflammation by arachidonate lipoxygenase products. (1991) (3)
- Mechanism of amphotericin-B (Ampho-B)-induced reduction of the glomerular filtration rate (GFR): a micropuncture study. (1990) (3)
- Endothelin and Endothelium-Derived Relaxing Factor in the Control of Glomerular Filtration and Renal Blood Flow (1990) (3)
- LTA4 hydrolase expression during glomerular inflammation: correlation of immunohistochemical localization with cytokine regulation. (1999) (3)
- Three global adaptations of the American medical education model (2013) (3)
- Discrepancies between two lipid-lowering guidelines for CVD prevention in seemingly healthy individuals-case study Lebanon. (2013) (2)
- Lipoxygenase products as mediators in immune-mediated glomerular injury. (1993) (2)
- Leukotriene D4 (LTD4)/leukotriene B4 (LTB4) interactions in the pathophysiology of experimental glomerulonephritis. (1989) (2)
- The glomerular physiology of lipoxin-A. (1988) (2)
- Effect of Targeted Curricular Reform on the Learning Environment, Student Empathy, and Hidden Curriculum in a Medical School: A 7-Year Longitudinal Study (2020) (2)
- Identification and characterization of an enhancer sequence in the promoter region of human 15-lipoxygenase (15-LO) gene. (1999) (2)
- Inhibition of 5-LO activating protein (FLAP) activity decreases proteinuria in streptozotocin (STZ)-induced diabetic rats. (2002) (2)
- Molecular cloning and functional expression of rat leukotriene A4 hydrolase using the polymerase chain reaction. (1992) (2)
- High plasma endothelin in hepatorenal syndrome (1991) (2)
- Inhibition of 5-LO activating protein (FLAP) activity decreases proteinuria in streptozotocin (STZ)-induced diabetic rats (1999) (1)
- First and second generation DESs reduce diabetes adverse effect on mortality and re-intervention in multivessel coronary disease: 9-Year analysis. (2017) (1)
- Debatehealthcare: a vision for transforming Lebanon into a regional academic hub (2010) (1)
- The academic health center (AHC) chief academic officer (CAO) role in fostering interprofessional learning experiences (2019) (1)
- The polyanthelmintic efficacy of levamisole. (1975) (1)
- Fractional excretion of chloride in prerenal azotemia. (1985) (1)
- Thromboxane A2 receptor antagonism reverses amphotericin B-induced renal vasoconstriction in the rat. (1990) (1)
- Alleviation of cisplatin nephrotoxicity: efficacy of local intra-arterial injection concomitant with hemodialysis. (1996) (1)
- Leukotrienes and 15-lipoxygenase products in glomerulonephritis. (1995) (1)
- Angiotensin II receptors: cloning, structure, function and regulation. (1993) (1)
- Roles for thromboxane A 2 and leukotrienes in endotoxin — induced acute renal failure (2015) (0)
- Divergence in intracellular signaling between interleukin-4 (IL-4) and IL-13 in human cells localizes to monomeric/dimeric expression of a transcription factor, the lupus autoantigen 70/80, induced by both cytokines. (1999) (0)
- Reversing the Brain Drain in Healthcare Education in Lebanon: A Success Story (2018) (0)
- Induction of Renal Arachidonate Cytochrome P-450 Epoxygenase After Uninephrectomy: Counterregulation of rf1 (1993) (0)
- The Functional Significance of Lipoxygenase Products of Arachidonic Acid in the Glomerular Microcirculation (1991) (0)
- PODOCYTURIA mRNAs: EARLIER AND SUPERIOR PREDICTORS OF CARDIOVASCULAR OUTCOMES (2016) (0)
- Nephrologists sans frontières: the return to Beirut. (2006) (0)
- Expression of 5-LO activating protein (FLAP) enhances albumin permeability in glomerular endothelial cells (GEC) (1999) (0)
- Effect of salt diet on beat-to-beat blood pressure and heart rate dynamics in hypertensive and non-hypertensive rats (2015) (0)
- 15-lipoxygenase-1 expression in prostate cancer: Correlation with mutant P53 expression and histologic grade (1999) (0)
- Inhibition of F2-isoprostane synthesis reduces proteinuria and improves renal function in streptozotocin (STZ)-induced diabetic rats (1999) (0)
- Interdependent roles of nitric oxide (NO) and 5-lipoxygenase (5-LO) during accelerated nephrotoxic serum nephritis (ants) in 5-lo gene deleted mice (5-LO-/-) (1996) (0)
- Oxidant stress in the pathogenesis of the hepatorenal syndrome (1993) (0)
- Arachidonic acid in cellular activation. (1999) (0)
- Use of lipoxin 4? and its derivatives as antagonists for trägreagierende anaphylaxmittel (1990) (0)
- 招請講演Glomerulonephritis: Future Therapeutic Strategies. (1995) (0)
- Transfection of rat kidney with human 15-lipoxygenase suppresses inflammation and preserves function in experimental glomerulonephritis (1999) (0)
- Beneficial effect of 5-lipoxygenase activating protein (FLAP) inhibition in accelerated nephrotoxic serum nephritis (aGN) and passive Heymann's nephritis (PHN) in rats (1999) (0)
- AN ATTEMPT TO HALT THE EVER-INCREASING PREVALENCE OF MORBIDITIES RESULTING FROM EXCESS DIETARY SODIUM INTAKE. The Lebanese Experience. (2016) (0)
- High glucose (HG)-induced synthesis of transforming growth factor β (TGF-β) in glomerular cells is driven by F2-isoprostane formation (1999) (0)
- The role of angiotensin II (AII) and cyclooxygenase products in mediating the systemic and renal vascular responses to leukotriene C4 (LTC4) infusion in the rat (1984) (0)
- Longitudinal study on the effect of surgical weight loss on beat-to-beat blood pressure variability in patients undergoing bariatric surgery: a study protocol (2021) (0)
- Podocyturia: an earlier biomarker of cardiovascular outcomes (2022) (0)
- Functional significance of lipoxygenase metabolites of arachidonic acid in the glomerular microcirculation. (1991) (0)
- Podocyturia mRNAs and Risk of Adverse Cardiovascular Outcomes from the Multi-Ethnic Study of Atherosclerosis (MESA): Preliminary Findings (2021) (0)
- Glomerular microcirculatory actions of leukotriene D4 in the rat: implications for glomerulonephritis. (1987) (0)
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