Karin Schallreuter
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German dermatologist
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Karin Schallreuter's Degrees
- Doctorate Medicine University of Hamburg
- PhD Dermatology University of Hamburg
Why Is Karin Schallreuter Influential?
(Suggest an Edit or Addition)According to Wikipedia, Karin Uta Schallreuter is a German-born medical scientist, and emerita professor for Clinical and Experimental Dermatology at the University of Bradford, England. She has researched the fields of vitiligo and eczema.
Karin Schallreuter's Published Works
Published Works
- Severity Scoring of Atopic Dermatitis: The SCORAD Index (1993) (1829)
- Hair follicle pigmentation. (2005) (457)
- A review of the worldwide prevalence of vitiligo in children/adolescents and adults (2012) (319)
- Low catalase levels in the epidermis of patients with vitiligo. (1991) (314)
- Regulation of melanin biosynthesis in the human epidermis by tetrahydrobiopterin. (1994) (313)
- Regulation of melanogenesis – controversies and new concepts (2008) (304)
- Adrenergic and cholinergic control in the biology of epidermis: physiological and clinical significance. (2006) (257)
- Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else? (2008) (200)
- Vitiligo and other diseases: coexistence or true association? Hamburg study on 321 patients. (1994) (176)
- Treatment of vitiligo with a topical application of pseudocatalase and calcium in combination with short-term UVB exposure: a case study on 33 patients. (1995) (162)
- The role of thioredoxin reductase in the reduction of free radicals at the surface of the epidermis. (1986) (158)
- Activation/deactivation of acetylcholinesterase by H2O2: more evidence for oxidative stress in vitiligo. (2004) (154)
- Defective tetrahydrobiopterin and catecholamine biosynthesis in the depigmentation disorder vitiligo. (1994) (151)
- Perturbed 6-tetrahydrobiopterin recycling via decreased dihydropteridine reductase in vitiligo: more evidence for H2O2 stress. (2004) (143)
- Oxidative stress in vitiligo: photo-oxidation of pterins produces H(2)O(2) and pterin-6-carboxylic acid. (2002) (125)
- A multicenter study on the use of pulsed low-intensity direct current for healing chronic stage II and stage III decubitus ulcers. (1993) (123)
- Catecholamines in human keratinocyte differentiation. (1995) (121)
- Free radical reduction in the human epidermis. (1989) (116)
- The mechanism of action of the nitrosourea anti-tumor drugs on thioredoxin reductase, glutathione reductase and ribonucleotide reductase. (1990) (114)
- Regulation of Human Epidermal Melanocyte Biology By β-Endorphin (2003) (111)
- Studies on the reactions between human tyrosinase, superoxide anion, hydrogen peroxide and thiols. (1991) (105)
- Production of catecholamines in the human epidermis. (1992) (102)
- Autocrine catecholamine biosynthesis and the beta-adrenoceptor signal promote pigmentation in human epidermal melanocytes. (2004) (101)
- Oxidative stress via hydrogen peroxide affects proopiomelanocortin peptides directly in the epidermis of patients with vitiligo. (2007) (97)
- Vitiligo and cutaneous melanoma. A case study. (1991) (95)
- Decreased Photodamage and Low Incidence of Non-Melanoma Skin Cancer in 136 Sun-Exposed Caucasian Patients with Vitiligo (2002) (90)
- Thioredoxin reductase - its role in epidermal redox status. (2001) (89)
- Koebner’s phenomenon in vitiligo: European position paper (2011) (88)
- Investigation of the personality structure in patients with vitiligo and a possible association with impaired catecholamine metabolism. (1995) (84)
- Histocompatibility antigens in vitiligo: Hamburg study on 102 patients from northern Germany. (1993) (82)
- From basic research to the bedside: efficacy of topical treatment with pseudocatalase PC‐KUS in 71 children with vitiligo (2008) (80)
- Hydrogen peroxide-mediated oxidative stress disrupts calcium binding on calmodulin: more evidence for oxidative stress in vitiligo. (2007) (74)
- A fully functional proopiomelanocortin/melanocortin-1 receptor system regulates the differentiation of human scalp hair follicle melanocytes. (2005) (72)
- The importance of L-phenylalanine transport and its autocrine turnover to L-tyrosine for melanogenesis in human epidermal melanocytes. (1999) (72)
- beta-Endorphin as a regulator of human hair follicle melanocyte biology. (2004) (69)
- Azelaic acid as a competitive inhibitor of thioredoxin reductase in human melanoma cells. (1987) (68)
- Enhanced DNA binding capacity on up‐regulated epidermal wild‐type p53 in vitiligo by H2O2‐mediated oxidation: a possible repair mechanism for DNA damage (2009) (68)
- Defective calcium uptake in keratinocyte cell cultures from vitiliginous skin (2004) (67)
- Regulation of human epidermal melanocyte biology by beta-endorphin. (2003) (67)
- Free radical reduction by thioredoxin reductase at the surface of normal and vitiliginous human keratinocytes. (1986) (66)
- Methionine sulfoxide reductases A and B are deactivated by hydrogen peroxide (H2O2) in the epidermis of patients with vitiligo. (2008) (66)
- Novel aspects in cutaneous biology of acetylcholine synthesis and acetylcholine receptors (2004) (66)
- Successful Treatment of Oxidative Stress in Vitiligo (1999) (65)
- A possible mechanism of action for azelaic acid in the human epidermis (2004) (65)
- Hydrogen peroxide regulates the cholinergic signal in a concentration dependent manner. (2007) (61)
- Blunted epidermal L‐tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 2: epidermal H2O2/ONOO–‐mediated stress in vitiligo hampers indoleamine 2,3‐dioxygenase and aryl hydrocarbon receptor‐mediated immune response signaling (2012) (59)
- Increased monoamine oxidase A activity in the epidermis of patients with vitiligo (2006) (58)
- Computer simulation of native epidermal enzyme structures in the presence and absence of hydrogen peroxide (H2O2): potential and pitfalls. (2006) (57)
- Hermansky-Pudlak syndrome in a Swiss population. (1993) (57)
- Stigmatisation, Avoidance Behaviour and Difficulties in Coping are Common Among Adult Patients with Vitiligo. (2015) (55)
- Oxybenzone oxidation following solar irradiation of skin: photoprotection versus antioxidant inactivation. (1996) (55)
- Modelling the hair follicle dermal papilla using spheroid cell cultures. (2010) (55)
- Regulation of tyrosinase by tetrahydropteridines and H2O2. (2004) (55)
- Presence of epidermal allantoin further supports oxidative stress in vitiligo (2008) (54)
- Pro-opiomelanocortin-related peptides, prohormone convertases 1 and 2 and the regulatory peptide 7B2 are present in melanosomes of human melanocytes. (2000) (53)
- Thioredoxin reductase. Role in free radical reduction in different hypopigmentation disorders. (1987) (52)
- Increased in vitro expression of beta2-adrenoceptors in differentiating lesional keratinocytes of vitiligo patients (2004) (50)
- Glutamate receptors on human melanocytes regulate the expression of MiTF. (2006) (49)
- Cytotoxicity of 6-biopterin to human melanocytes. (1994) (47)
- Blunted epidermal L‐tryptophan metabolism in vitiligo affects immune response and ROS scavenging by Fenton chemistry, part 1: epidermal H2O2/ONOO–‐mediated stress abrogates tryptophan hydroxylase and dopa decarboxylase activities, leading to low serotonin and melatonin levels (2012) (47)
- Human phenylalanine hydroxylase is activated by H2O2: a novel mechanism for increasing the L-tyrosine supply for melanogenesis in melanocytes. (2004) (47)
- Increased epidermal functioning wild‐type p53 expression in vitiligo (2003) (47)
- Decreased phenylalanine uptake and turnover in patients with vitiligo. (2005) (46)
- Estrogens can contribute to hydrogen peroxide generation and quinone-mediated DNA damage in peripheral blood lymphocytes from patients with vitiligo. (2006) (45)
- Functioning methionine sulfoxide reductases A and B are present in human epidermal melanocytes in the cytosol and in the nucleus. (2006) (44)
- Cholesterol regulates melanogenesis in human epidermal melanocytes and melanoma cells (2009) (43)
- Pteridines in the control of pigmentation. (1997) (43)
- The stereospecific suicide inhibition of human melanoma thioredoxin reductase by 13-cis-retinoic acid. (1989) (43)
- Regulation of pigmentation in human epidermal melanocytes by functional high-affinity beta-melanocyte-stimulating hormone/melanocortin-4 receptor signaling. (2009) (42)
- Basic evidence for epidermal H2O2/ONOO–‐mediated oxidation/nitration in segmental vitiligo is supported by repigmentation of skin and eyelashes after reduction of epidermal H2O2 with topical NB‐UVB‐activated pseudocatalase PC‐KUS (2013) (41)
- The role of calcium in the regulation of free radical reduction by thioredoxin reductase at the surface of the skin. (1986) (40)
- KdPT, a Tripeptide Derivative of α-Melanocyte–Stimulating Hormone, Suppresses IL-1β–Mediated Cytokine Expression and Signaling in Human Sebocytes (2010) (40)
- Butyrylcholinesterase is present in the human epidermis and is regulated by H2O2: more evidence for oxidative stress in vitiligo. (2006) (38)
- Specific interaction of the diastereomers 7(R)‐ and 7(S)‐tetrahydrobiopterin with phenylalanine hydroxylase: implications for understanding primapterinuria and vitiligo (2006) (36)
- In vivo fluorescence excitation spectroscopy and in vivo Fourier‐transform Raman spectroscopy in human skin: evidence of H2O2 oxidation of epidermal albumin in patients with vitiligo (2004) (36)
- Advances in melanocyte basic science research. (2007) (35)
- A novel mechanism in control of human pigmentation by {beta}-melanocyte-stimulating hormone and 7-tetrahydrobiopterin. (2005) (35)
- EF-hands calcium binding regulates the thioredoxin reductase/thioredoxin electron transfer in human keratinocytes (1989) (34)
- UVA-irradiated pheomelanin alters the structure of catalase and decreases its activity in human skin. (2006) (34)
- Anthralin inhibits elevated levels of thioredoxin reductase in psoriasis. A new mode of action for this drug. (1987) (30)
- Evidence for specific complex formation between alpha-melanocyte stimulating hormone and 6(R)-L-erythro-5,6,7,8-tetrahydrobiopterin using near infrared Fourier transform Raman spectroscopy. (1999) (28)
- The activity and purification of membrane-associated thioredoxin reductase from human metastatic melanotic melanoma. (1988) (28)
- Disease‐related behavioral patterns and experiences affect quality of life in children and adolescents with vitiligo (2014) (28)
- Molecular evidence that halo in Sutton’s naevus is not vitiligo (2003) (28)
- Reduced thioredoxin inhibits melanin biosynthesis: Evidence for the formation of a stable bis-cysteinate complex with tyrosinase (1988) (28)
- Positive phase II study in the treatment of advanced malignant melanoma with fotemustine (2004) (28)
- In situ and in vitro evidence for DCoH/HNF-1 alpha transcription of tyrosinase in human skin melanocytes. (2003) (27)
- Altered catecholamine synthesis and degradation in the epidermis of patients with atopic eczema (1997) (26)
- Calcium regulates thioredoxin reductase in human metastatic melanoma. (1989) (25)
- The induction of the α‐1‐adrenoceptor signal transduction system on human melanocytes (1996) (25)
- Thioredoxin reductase induction coincides with melanin biosynthesis in brown and black guinea pigs and in murine melanoma cells. (1994) (24)
- Controversies in Experimental Dermatology: What exactly is “atopy”? (1998) (24)
- Calcium-activated butyrylcholinesterase in human skin protects acetylcholinesterase against suicide inhibition by neurotoxic organophosphates. (2007) (24)
- Computer simulation of heterogeneous single nucleotide polymorphisms in the catalase gene indicates structural changes in the enzyme active site, NADPH‐binding and tetramerization domains: a genetic predisposition for an altered catalase in patients with vitiligo? (2008) (24)
- Thioredoxin reductase activity in Hermansky-Pudlak syndrome: a method for identification of putative heterozygotes. (1988) (23)
- Significant immediate and long-term improvement in quality of life and disease coping in patients with vitiligo after group climatotherapy at the Dead Sea. (2011) (22)
- The Ca2+-binding capacity of epidermal furin is disrupted by H2O2-mediated oxidation in vitiligo. (2008) (22)
- 6-Tetrahydrobiopterin functions as a UVB-light switch for de novo melanogenesis. (1998) (22)
- Functioning methionine-S-sulfoxide reductases A and B are present in human skin. (2005) (22)
- Cumulative life course impairment in vitiligo. (2013) (19)
- Cutaneous malignant melanomas with other coexisting neoplasms: a true association? (1993) (19)
- Turmeric (curcumin): a widely used curry ingredient, can contribute to oxidative stress in Asian patients with acute vitiligo. (2006) (18)
- Beta‐adrenergic blocking drugs may exacerbate vitiligo (1995) (17)
- Does melanin affect the low LET radiation response of Cloudman S91 mouse melanoma cell lines? (1991) (17)
- GTP cyclohydrolase feedback regulatory protein controls cofactor 6-tetrahydrobiopterin synthesis in the cytosol and in the nucleus of epidermal keratinocytes and melanocytes. (2006) (17)
- Thioredoxin reductase in control of the pigmentary system. (1989) (17)
- The vesicular acetylcholine transporter is present in melanocytes and keratinocytes in the human epidermis. (2006) (17)
- H2O2‐mediated oxidation of tetrahydrobiopterin: Fourier transform Raman investigations provide mechanistic implications for the enzymatic utilization and recycling of this essential cofactor (2002) (16)
- Identification of epidermal L‐tryptophan and its oxidation products by in vivo FT‐Raman Spectroscopy further supports oxidative stress in patients with vitiligo (2008) (16)
- Melanocortins in human melanocytes. (2006) (16)
- What exactly is "atopy"? (1998) (14)
- Quinones are reduced by 6-tetrahydrobiopterin in human keratinocytes, melanocytes, and melanoma cells. (2008) (14)
- Sensitivity and resistance in human metastatic melanoma to the new chloroethylnitrosourea anti-tumor drug Fotemustine. (1991) (13)
- Vitix®– a new treatment for vitiligo? (2005) (13)
- Local treatment of cutaneous and subcutaneous metastatic malignant melanoma with fotemustine (2004) (13)
- EF-hands calcium binding regulates the thioredoxin reductase/thioredoxin electron transfer in human keratinocytes. (1989) (13)
- New aspects in the pathophysiology of cutaneous melanoma: a review of the role of thioproteins and the effect of nitrosoureas. (1991) (12)
- PUVA for vitiligo and skin cancer. (1997) (11)
- H2O2 increases de novo synthesis of (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin via GTP cyclohydrolase I and its feedback regulatory protein in vitiligo (2009) (11)
- The allergenicity of complex cations. (1986) (11)
- In vitro and in vivo identification of ‘pseudocatalase’ activity in Dead Sea water using Fourier transform Raman spectroscopy (2002) (11)
- The effect of UV radiation and sun blockers on free radical defence in human and guinea pig epidermis (2004) (11)
- Defects in antioxidant defense and calcium transport in the epidermis of xeroderma pigmentosum patients (2004) (10)
- Total serum immunoglobulins and atopic symptoms in patients with vitiligo. (1994) (10)
- [3H]-13-cis-retinoic acid covalently binds to thioredoxin reductase in human keratinocytes. (1991) (9)
- m2 muscarinic acetylcholine receptor (mAchR) subtype is present in human epidermal keratinocytes in situ and in vivo. (2004) (9)
- Structural and functional alterations in the β2‐adrenoceptor are caused by a point mutation in patients with atopic eczema (2007) (9)
- Regulation of tyrosinase by tetrahydropteridines--what is real? A critical reanalysis of H. Wojtasek's view. (2005) (9)
- [Vitiligo. What is new?]. (2010) (8)
- Calcium transport and regulation in human primary and metastatic melanoma. (1992) (8)
- Ribonucleotide diphosphate reductase from human metastatic melanoma (1992) (7)
- Ineffective topical treatment of vitiligo with Cucumis melo extracts * (2011) (7)
- The Ca2+ binding capacity of epidermal furin is disrupted by H2O2-mediated oxidation in vitiligo (2008) (6)
- Tryptophan protects human melanoma cells against gamma-interferon and tumour necrosis factor-alpha: a unifying mechanism of action. (1991) (6)
- In vivo and in vitro evidence for epidermal H2O2‐mediated oxidative stress in piebaldism (2009) (6)
- Nitroxide radical reduction in nude mouse skin. (1990) (5)
- Controversies in Experimental Dermatology (1998) (5)
- GTP-cyclohydrolase and vitiligo (1997) (5)
- Q10‐triggered facial vitiligo (2013) (5)
- Biochemical Theory of Vitiligo: a Role of Pteridines in Pigmentation (2008) (4)
- An uncommon onset of myeloma. (1985) (3)
- On Photo-Stability of Oxybenzone (1998) (3)
- Raman Spectroscopic Studies Showing the UV Stability of Oxybenzone (1998) (3)
- Stimulation of melanin synthesis in melanoma cells by cold plasma (2018) (3)
- [Hermansky-Pudlak syndrome]. (1989) (2)
- Inhibition of the prohormone convertase subtilisin-kexin isoenzyme-1 induces apoptosis in human melanoma cells. (2014) (2)
- Photo-Oxidation of Sepiapterin Produces Pterin-6-Carboxylic Acid and H 2 O 2 in Vitro (2002) (2)
- Downregulation of tyrosinase activity in human melanocyte cell cultures by yohimbine. (2000) (2)
- Pseudocatalase in the Treatment of Vitiligo (2008) (2)
- A probable mechanism for hyperpigmentation by fotemustine. (1992) (2)
- [Camptodactyly. The syndrome of flexion contracture of the fingers]. (1993) (2)
- Regulation of thioredoxin reductase by calcium in Hermansky-Pudlak syndrome (2004) (2)
- Increased levels of anxious-depressive mood in parents of children with vitiligo. (2018) (2)
- Human epidermal proopiomelanocortin (POMC) cDNA variant is identical to mouse POMC cDNA. (1999) (2)
- Successful treatment of vitiligo with pseudocatalase, calcium and short-term UVB exposure: 38 (1995) (1)
- The Spectrum of Photodamage and its Treatment (1995) (1)
- ON PHOTO-STABILITY OF OXYBENZONE. AUTHORS' REPLY (1998) (1)
- Evidence for active L-tyrosine de novo synthesis in human epidermal melanocytes and keratinocytes (1998) (1)
- Successful treatment of epidermal hydrogen peroxide (H2O2) stress in vitiligo with a topical pseudocatalase (1998) (1)
- [Eosinophilia-myalgia syndrome. Clinical aspects and follow-up of 10 patients]. (1992) (1)
- Reactive Oxygen Species and Reactive Nitrogen Species in Vitiligo (2014) (1)
- Viewpoint 1 (2008) (1)
- Contents, Vol. 188, 1994 (1994) (0)
- Contents, Vol. 183, 1991 (1991) (0)
- Autocrine catecholamine biosynthesis and the b- adrenoceptor signal is present in Human Epidermal Melanocytes (2009) (0)
- Announcement – International Conference on the Molecular Pharmacology of the Skin (1991) (0)
- P5 Tryptophan protects human melanoma cells against the cytotoxicity of gamma interferon and tumor necrosis factor alpha (1991) (0)
- [Successful topical treatment of chronic cutaneous leishmaniasis with paromomycin sulfate (15%) and methylbenzethonium chloride (12%)]. (1994) (0)
- Determination of Sepiapterin and Sepiapterin Reductase in Human Skin (2002) (0)
- The role of catecholamines in vitiligo (1993) (0)
- Evidence for epidermal acetylcholine accumulation after oxidative stress by H2O2 and possible implications (2008) (0)
- Functional melanocytes are present in white epidermis in vitiligo of long duration (1998) (0)
- Contents, Vol. 187, 1993 (1993) (0)
- The transcription of the tyrosinase gene by pterin-4a-carbinolamine dehydratase dimerization with transcription factor hepatocyte nuclear factor 1: 9 (1995) (0)
- Author index (2005) (0)
- Decreased levels of 6-tetrahydrobiopterin in psoriatic epidermis (1998) (0)
- Studies on the tetrahydrobiopterin regulatory binding domain on tyrosinase: 8 (1995) (0)
- 9th Symposium of CIRD Galderma – Oral Presentations (1991) (0)
- Pseudocatalase treatment in xeroderma pigmentosum: a case report. (1999) (0)
- Validity of the `Bioassay' for Thioredoxin-Reductase Activity-Reply (1988) (0)
- Reviewers' list (2005) (0)
- Vitiligo: in vivo and in vitro evidence for epidermal ROS/RNS-mediated regulation / dysregulation (2014) (0)
- 4 a-carbinolamine dehydratase (DCoH) controls the supply of L-tyrosine as well as the transcription of the tyrosinase gene in human melanocytes (1998) (0)
- Defective catecholamine biosynthesis and increased mao-activity in the uninvolved epidermis of patients with atopic eczema (1994) (0)
- β-Endorphin/β MSH – two neglected melanotropins? (2008) (0)
- The (6R) 5,6,7,8 tetrahydrobiopterin/6‐biopterin redox cycle controls melanogenesis and viability in human melanocytes (1994) (0)
- Composition and method for treatment of disorders in the form of depigmentation (1992) (0)
- 9th Symposium of CIRD Galderma – Posters (1991) (0)
- Announcement – 46th Brazilian Congress of Dermatology (1991) (0)
- Letters to the Editor - Turmeric (curcumin): A widely used curry ingredient, can contribute to oxidative stress in asian patients with acutevitiligo (2006) (0)
- GTP-cyclohydrolase I and vitiligo. (2000) (0)
- Influence of Hydrogen Peroxide (H2O2) on Pterin Homeostasis in the Depigmentation Disorder Vitiligo (2002) (0)
- More evidence that pterins can function as a ‘light switch’ in the pigmentation process: 33 (1995) (0)
- [Ulcerative angiosarcoma of the cranial vault masquerading as a pyoderma]. (1989) (0)
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