Karin Scharffetter‐kochanek
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Philosophy
Karin Scharffetter‐kochanek's Degrees
- Doctorate Medicine University of Cologne
- PhD Medicine University of Cologne
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(Suggest an Edit or Addition)Karin Scharffetter‐kochanek's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. (2011) (833)
- p16INK4A is a robust in vivo biomarker of cellular aging in human skin (2006) (466)
- Spontaneous Skin Ulceration and Defective T Cell Function in CD18 Null Mice (1998) (432)
- Solar UV irradiation and dermal photoaging. (2001) (425)
- Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation. (2012) (418)
- Photoaging of the skin from phenotype to mechanisms (2000) (418)
- UV-induced reactive oxygen species in photocarcinogenesis and photoaging. (1997) (410)
- Ultraviolet‐B Irradiation and Matrix Metalloproteinases (2002) (345)
- Role of β2-integrins for homing and neovascularization capacity of endothelial progenitor cells (2005) (316)
- Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice (1997) (302)
- Transit time of leukocytes rolling through venules controls cytokine-induced inflammatory cell recruitment in vivo. (1998) (302)
- A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing (2013) (268)
- UVA‐INDUCED AUTOCRINE STIMULATION OF FIBROBLAST‐DERIVED COLLAGENASE/MMP‐1 BY INTERRELATED LOOPS OFINTERLEUKIN–1 andINTERLEUKIN–6 (1994) (262)
- The registry of the German Network for Systemic Scleroderma: frequency of disease subsets and patterns of organ involvement (2008) (253)
- Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation. (2006) (234)
- Ultraviolet-B irradiation and matrix metalloproteinases: from induction via signaling to initial events. (2002) (233)
- Central Role of Ferrous/Ferric Iron in the Ultraviolet B Irradiation-mediated Signaling Pathway Leading to Increased Interstitial Collagenase (Matrix-degrading Metalloprotease (MMP)-1) and Stromelysin-1 (MMP-3) mRNA Levels in Cultured Human Dermal Fibroblasts* (1998) (230)
- Stable Overexpression of Manganese Superoxide Dismutase in Mitochondria Identifies Hydrogen Peroxide as a Major Oxidant in the AP-1-mediated Induction of Matrix-degrading Metalloprotease-1* (1999) (228)
- Singlet oxygen may mediate the ultraviolet A-induced synthesis of interstitial collagenase. (1995) (222)
- Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation. (2006) (214)
- TSG-6 released from intradermally injected mesenchymal stem cells accelerates wound healing and reduces tissue fibrosis in murine full-thickness skin wounds. (2014) (204)
- Molecular mechanisms of the crosstalk between mitochondria and NADPH oxidase through reactive oxygen species-studies in white blood cells and in animal models. (2014) (197)
- Manganese superoxide dismutase and aldehyde dehydrogenase deficiency increase mitochondrial oxidative stress and aggravate age-dependent vascular dysfunction. (2008) (197)
- UV-induced oxidative stress and photoaging. (2001) (197)
- Oxidative stress in chronic venous leg ulcers (2005) (196)
- Hydrogen peroxide (H2O2) increases the steady-state mRNA levels of collagenase/MMP-1 in human dermal fibroblasts. (1997) (194)
- Neutrophil primary granule proteins HBP and HNP1-3 boost bacterial phagocytosis by human and murine macrophages. (2008) (188)
- UVA irradiation stimulates the synthesis of various matrix‐metalloproteinases (MMPs) in cultured human fibroblasts (1993) (179)
- Wound‐healing defect of CD18−/− mice due to a decrease in TGF‐β1 and myofibroblast differentiation (2005) (157)
- Disclosure of the Culprits: Macrophages-Versatile Regulators of Wound Healing. (2013) (156)
- Chronological ageing and photoageing of the fibroblasts and the dermal connective tissue (2001) (153)
- Singlet oxygen induces collagenase expression in human skin fibroblasts (1993) (150)
- Tumour necrosis factor α secretion induces protease activation and acinar cell necrosis in acute experimental pancreatitis in mice (2012) (150)
- Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyte‐expressed protein (2004) (145)
- UVA-induced autocrine stimulation of fibroblast-derived-collagenase by IL-6: a possible mechanism in dermal photodamage? (1993) (142)
- β2 integrin mediates hantavirus-induced release of neutrophil extracellular traps (2014) (139)
- NADPH oxidase is required for neutrophil‐dependent autoantibody‐induced tissue damage (2007) (134)
- Singlet oxygen is an early intermediate in cytokine‐dependent ultraviolet‐A induction of interstitial collagenase in human dermal fibroblasts in vitro (1997) (133)
- Active MAC-1 (CD11b/CD18) on DCs inhibits full T-cell activation. (2007) (131)
- Hepatic activation of IKK/NFκB signaling induces liver fibrosis via macrophage‐mediated chronic inflammation (2012) (121)
- Cell Adhesion and Migration Properties of β2-Integrin Negative Polymorphonuclear Granulocytes on Defined Extracellular Matrix Molecules (2001) (120)
- A role for β2 integrins (CD11/CD18) in the regulation of cytokine gene expression of polymorphonuclear neutrophils during the inflammatory response (1999) (116)
- Myocardial fibrosis in transforming growth factor‐β1 (TGF‐β1) transgenic mice is associated with inhibition of interstitial collagenase (2002) (114)
- Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo. (2005) (109)
- Suppression of Neutrophil-Mediated Tissue Damage—A Novel Skill of Mesenchymal Stem Cells (2016) (107)
- Adaptive antioxidant response of manganese-superoxide dismutase following repetitive UVA irradiation. (1999) (107)
- The Vav binding site of the non-receptor tyrosine kinase Syk at Tyr 348 is critical for beta2 integrin (CD11/CD18)-mediated neutrophil migration. (2006) (103)
- Activation of p70 Ribosomal Protein S6 Kinase Is an Essential Step in the DNA Damage-dependent Signaling Pathway Responsible for the Ultraviolet B-mediated Increase in Interstitial Collagenase (MMP-1) and Stromelysin-1 (MMP-3) Protein Levels in Human Dermal Fibroblasts* (2000) (103)
- German guidelines for the diagnosis and therapy of localized scleroderma (2016) (100)
- A polygenic mouse model of psoriasiform skin disease in CD18-deficient mice. (1996) (99)
- The effect of adipose tissue derived MSCs delivered by a chemically defined carrier on full-thickness cutaneous wound healing. (2013) (98)
- Treatment of recalcitrant cicatricial pemphigoid with the tumor necrosis factor alpha antagonist etanercept. (2002) (97)
- Selective pick-up of increased iron by deferoxamine-coupled cellulose abrogates the iron-driven induction of matrix-degrading metalloproteinase 1 and lipid peroxidation in human dermal fibroblasts in vitro: a new dressing concept. (2001) (95)
- CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks. (2008) (95)
- Heterozygous Deficiency of Manganese Superoxide Dismutase in Mice (Mn-SOD+/-): A Novel Approach to Assess the Role of Oxidative Stress for the Development of Nitrate Tolerance (2005) (93)
- Adaptive antioxidant response protects dermal fibroblasts from UVA-induced phototoxicity. (2001) (93)
- Different pattern of collagen cross-links in two sclerotic skin diseases: lipodermatosclerosis and circumscribed scleroderma. (2001) (87)
- Accelerated aging phenotype in mice with conditional deficiency for mitochondrial superoxide dismutase in the connective tissue (2011) (86)
- RhoH is important for positive thymocyte selection and T-cell receptor signaling. (2007) (82)
- Protease inhibitors protect growth factor activity in chronic wounds (1997) (81)
- A role for apoptosis in the control of neutrophil homeostasis in the circulation: insights from CD18-deficient mice. (2003) (81)
- Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells. (2002) (79)
- TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis. (2008) (78)
- alpha-melanocyte-stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: melanocortin peptides as a novel treatment strategy for scleroderma? (2009) (77)
- Targeting NF-κB with a Natural Triterpenoid Alleviates Skin Inflammation in a Mouse Model of Psoriasis1 (2009) (75)
- Neutrophils in Tissue Trauma of the Skin, Bone, and Lung: Two Sides of the Same Coin (2018) (73)
- Mg2+ and Ca2+ differentially regulate beta 1 integrin-mediated adhesion of dermal fibroblasts and keratinocytes to various extracellular matrix proteins. (1994) (71)
- Overexpression of Phospholipid-hydroperoxide Glutathione Peroxidase in Human Dermal Fibroblasts Abrogates UVA Irradiation-induced Expression of Interstitial Collagenase/Matrix Metalloproteinase-1 by Suppression of Phosphatidylcholine Hydroperoxide-mediated NFκB Activation and Interleukin-6 Release* (2004) (71)
- Linking neuron and skin: Matrix metalloproteinases in amyotrophic lateral sclerosis (ALS) (2009) (69)
- Impairment of neutrophil emigration in CD18-null mice. (1999) (69)
- Migration of a Human Keratinocyte Cell Line (HACAT) to Interstitial Collagen Type I Is Mediated by the α2β1-Integrin Receptor (1992) (66)
- Wound healing defect of Vav3-/- mice due to impaired {beta}2-integrin-dependent macrophage phagocytosis of apoptotic neutrophils. (2009) (66)
- Myocardial fibrosis in transforming growth factor-beta(1) (TGF-beta(1)) transgenic mice is associated with inhibition of interstitial collagenase. (2002) (66)
- Connective Tissue and Fibroblast Senescence in Skin Aging. (2021) (66)
- Ultraviolet B Wavelength Dependence for the Regulation of Two Major Matrix‐Metalloproteinases and Their Inhibitor TIMP‐1 in Human Dermal Fibroblasts (1996) (65)
- Expression of stromal cell markers in distinct compartments of human skin cancers (2006) (65)
- MMP-2 and MMP-9 are elevated in spinal cord and skin in a mouse model of ALS (2010) (63)
- Class IA Phosphoinositide 3-Kinase β and δ Regulate Neutrophil Oxidase Activation in Response to Aspergillus fumigatus Hyphae (2011) (63)
- Optical Coherence Tomography: Clinical Applications in Dermatology (2003) (61)
- Acral Erythrodysesthesia Syndrome Caused by Intravenous Infusion of Docetaxel in Breast Cancer (2002) (61)
- Bath-PUVA therapy in three patients with scleredema adultorum. (1998) (61)
- Photosensitization of uroporphyrin augments the ultraviolet A-induced synthesis of matrix metalloproteinases in human dermal fibroblasts. (1996) (59)
- PUVA therapy for disabling pansclerotic morphoea of children. (1998) (58)
- Photoaging of the connective tissue of skin: its prevention and therapy. (1997) (58)
- Reduced CD18 Levels Drive Regulatory T Cell Conversion into Th17 Cells in the CD18hypo PL/J Mouse Model of Psoriasis (2013) (58)
- Psoralen photoactivation promotes morphological and functional changes in fibroblasts in vitro reminiscent of cellular senescence. (1998) (57)
- Ultraviolet B Wavelength Dependence for the Regulation of Two Major Matrix‐Metalloproteinases and Their Inhibitor TIMP‐1 in Human Dermal Fibroblasts (1996) (56)
- Pathogenesis of wound healing disorders in the elderly (2017) (54)
- In experimental leishmaniasis deficiency of CD18 results in parasite dissemination associated with altered macrophage functions and incomplete Th1 cell response (2000) (52)
- Key role of macrophages in the pathogenesis of CD18 hypomorphic murine model of psoriasis. (2009) (52)
- The role of manganese superoxide dismutase in skin aging (2012) (52)
- CD5+ B cells from individuals with systemic lupus erythematosus express granzyme B (2010) (52)
- Recommendation: Daily sun protection in the prevention of chronic UV‐induced skin damage (2007) (51)
- Induction of beta 1 integrin synthesis by recombinant platelet-derived growth factor (PDGF-AB) correlates with an enhanced migratory response of human dermal fibroblasts to various extracellular matrix proteins. (1995) (51)
- Syk-Mediated Translocation of PI3Kδ to the Leading Edge Controls Lamellipodium Formation and Migration of Leukocytes (2007) (50)
- ABCB5 Identifies Immunoregulatory Dermal Cells. (2015) (49)
- Beta2 integrins separate graft-versus-host disease and graft-versus-leukemia effects. (2008) (49)
- Reactive oxygen intermediate-induced pathomechanisms contribute to immunosenescence, chronic inflammation and autoimmunity (2009) (48)
- CD4+ T Cell-Associated Pathophysiology Critically Depends on CD18 Gene Dose Effects in a Murine Model of Psoriasis 1 (2003) (48)
- [AWMF Guideline no. 013/066. Diagnosis and therapy of circumscribed scleroderma]. (2009) (48)
- Epidermolysis bullosa acquisita — successful treatment with colchicine (2004) (48)
- Phototherapy and photochemotherapy. (2008) (47)
- Photoaging as a consequence of natural and therapeutic ultraviolet irradiation—studies on PUVA-induced senescence-like growth arrest of human dermal fibroblasts (2003) (46)
- Improvement of cold urticaria by treatment with the leukotriene receptor antagonist montelukast. (2000) (46)
- Solitary cutaneous dendritic cell tumor in a child: role of dendritic cell markers for the diagnosis of skin Langerhans cell histiocytosis. (2005) (46)
- Alpha-melanocyte stimulating hormone induces collagenase/matrix metalloproteinase-1 in human dermal fibroblasts. (1995) (46)
- A model of the onset of the senescence associated secretory phenotype after DNA damage induced senescence (2017) (45)
- The role of vitamin C in pushing back the boundaries of skin aging: an ultrasonographic approach (2015) (44)
- Cockayne syndrome protein A is a transcription factor of RNA polymerase I and stimulates ribosomal biogenesis and growth (2014) (44)
- Vascular endothelial growth factor causally contributes to the angiogenic response upon ultraviolet B irradiation in vivo (2002) (43)
- Acquired perforating collagenosis: is it due to damage by scratching? (2001) (42)
- Activation of protein kinase CK2 is an early step in the ultraviolet B-mediated increase in interstitial collagenase (matrix metalloproteinase-1; MMP-1) and stromelysin-1 (MMP-3) protein levels in human dermal fibroblasts. (2002) (42)
- Topical silver and gold nanoparticles complexed with Cornus mas suppress inflammation in human psoriasis plaques by inhibiting NF‐κB activity (2018) (42)
- Ultraviolet‐B induction of interstitial collagenase and stromelyin‐1 occurs in human dermal fibroblasts via an autocrine interleukin‐6‐dependent loop (1999) (42)
- Mitochondrial oxidative stress and nitrate tolerance – comparison of nitroglycerin and pentaerithrityl tetranitrate in Mn-SOD+/- mice (2006) (41)
- Cutting Edge: Egress of Newly Generated Plasma Cells from Peripheral Lymph Nodes Depends on β2 Integrin1 (2005) (40)
- Diagnosis and Therapy of Localized Scleroderma (2009) (39)
- Artefactual effects of oxygen on cell culture models of cellular senescence and stem cell biology (2011) (39)
- Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration (2016) (39)
- Calcinosis of the cutis and subcutis: an unusual nonimmunologic adverse reaction to subcutaneous injections of low-molecular-weight calcium-containing heparins. (2004) (38)
- Truncated Cockayne syndrome B protein represses elongation by RNA polymerase I. (2008) (38)
- Telomerase stimulates ribosomal DNA transcription under hyperproliferative conditions (2014) (38)
- Small molecular antioxidants effectively protect from PUVA-induced oxidative stress responses underlying fibroblast senescence and photoaging. (2008) (38)
- DNA Damage-Induced HSPC Malfunction Depends on ROS Accumulation Downstream of IFN-1 Signaling and Bid Mobilization. (2016) (37)
- Interplay of H2A deubiquitinase 2A-DUB/Mysm1 and the p19ARF/p53 axis in hematopoiesis, early T-cell development and tissue differentiation (2015) (37)
- Efficacy of danazol treatment in a patient with the new variant of hereditary angio‐oedema (HAE III) (2004) (37)
- Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model. (2013) (37)
- Activated neutrophils exert antitumor activity against human melanoma cells: reactive oxygen species-induced mechanisms and their modulation by granulocyte-macrophage-colony-stimulating factor. (2003) (37)
- Senescent BALB/c Mice Are Able To Develop Resistance to Leishmania major Infection (2004) (36)
- Iron and iron-dependent reactive oxygen species in the regulation of macrophages and fibroblasts in non-healing chronic wounds. (2019) (36)
- Mesenchymal Stem Cells Adaptively Respond to Environmental Cues Thereby Improving Granulation Tissue Formation and Wound Healing (2020) (36)
- Bullous Pemphigoid in a Patient Treated with UVA-1 Phototherapy for Disseminated Morphea (2001) (36)
- 8‐Isoprostane is a dose‐related biomarker for photo‐oxidative ultraviolet (UV) B damage in vivo: a pilot study with personal UV dosimetry (2006) (35)
- TLR4‐dependent shaping of the wound site by MSCs accelerates wound healing (2020) (35)
- Efficacy of bath psoralen plus ultraviolet A (PUVA) vs. system PUVA in psoriasis: a prospective, open, randomized, multicentre study (2013) (35)
- The Proangiogenic Capacity of Polymorphonuclear Neutrophils Delineated by Microarray Technique and by Measurement of Neovascularization in Wounded Skin of CD18-Deficient Mice (2005) (34)
- In vivo safety profile and biodistribution of GMP-manufactured human skin-derived ABCB5-positive mesenchymal stromal cells for use in clinical trials (2019) (33)
- S1‐Guidelines on UV phototherapy and photochemotherapy (2016) (33)
- Newly Defined ATP‐Binding Cassette Subfamily B Member 5 Positive Dermal Mesenchymal Stem Cells Promote Healing of Chronic Iron‐Overload Wounds via Secretion of Interleukin‐1 Receptor Antagonist (2019) (33)
- Modeling trauma in rats: similarities to humans and potential pitfalls to consider (2019) (32)
- Site of blood vessel damage and relevance of CD18 in a murine model of immune complex-mediated vasculitis. (2007) (32)
- The gene expression profile of psoralen plus UVA-induced premature senescence in skin fibroblasts resembles a combined DNA-damage and stress-induced cellular senescence response phenotype (2007) (32)
- β2 Integrin (CD11/CD18)‐mediated signaling involves tyrosine phosphorylation of c‐Cbl in human neutrophils (2000) (31)
- Protective and determining factors for the overall lipid peroxidation in ultraviolet A1‐irradiated fibroblasts: in vitro and in vivo investigations (2003) (31)
- Induction of Manganese Superoxide Dismutase in Human Dermal Fibroblasts: A UV-B–Mediated Paracrine Mechanism With the Release of EpidermalInterleukin 1α, Interleukin 1β, and Tumor Necrosis Factor α (2002) (31)
- Immediate Reaction to Roxithromycin and Prick Test Cross-Sensitization to Erythromycin and Clarithromycin (1998) (31)
- Superoxide anion radicals induce IGF-1 resistance through concomitant activation of PTP1B and PTEN (2014) (30)
- Loss of Proteostasis Is a Pathomechanism in Cockayne Syndrome. (2018) (30)
- Acquired relapsing self-healing Blaschko dermatitis. (1994) (30)
- Unexpected delayed‐type hypersensitivity skin reactions to the ultra‐low‐molecular‐weight heparin fondaparinux (2005) (29)
- Successful treatment of lichen amyloidosis with combined bath PUVA photochemotherapy and oral acitretin (2006) (29)
- Successful sulfasalazine treatment of severe chronic idiopathic urticaria associated with pressure urticaria. (2001) (28)
- The first peak of the UVB irradiation‐dependent biphasic induction of vascular endothelial growth factor (VEGF) is due to phosphorylation of the epidermal growth factor receptor and independent of autocrine transforming growth factor α (2000) (28)
- Treatment of pruritus by capsaicin in a patient with pityriasis rubra pilaris receiving RE‐PUVA therapy (2000) (28)
- Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington’s disease (2017) (27)
- Effect of exercise on bone and articular cartilage in heterozygous manganese superoxide dismutase (SOD2) deficient mice (2011) (26)
- Fondaparinux as a novel therapeutic alternative in a patient with heparin allergy (2004) (25)
- Acquired reactive perforating collagenosis triggered by scabies infection. (2000) (25)
- Psoralen plus UVA (PUVA) induced premature senescence as a model for stress-induced premature senescence (2002) (24)
- Management of Refractory Early-Stage Cutaneous T-Cell Lymphoma (2006) (24)
- Divalent cations (Mg2+, Ca2+) differentially influence the β1 integrin‐mediated migration of human fibroblasts and keratinocytes to different extracellular matrix proteins (1995) (24)
- Diabetes mellitus and the skin (2016) (24)
- Exercise-induced adaptations of cardiac redox homeostasis and remodeling in heterozygous SOD2-knockout mice. (2011) (24)
- Management of refractory early-stage cutaneous T-cell lymphoma (mycosis fungoides) with a combination of oral bexarotene and psoralen plus ultraviolet bath therapy. (2004) (24)
- β 2 integrins are required for skin homing of primed T cells but not for priming naive T cells (2002) (23)
- A 9-Centimorgan Interval of Chromosome 10 Controls the T Cell-Dependent Psoriasiform Skin Disease and Arthritis in a Murine Psoriasis Model1 (2008) (22)
- Occupational contact sensitivity to aluminium in a machine construction plant worker (1998) (22)
- Direct comparison of [18F]FDG PET/CT with PET alone and with side-by-side PET and CT in patients with malignant melanoma (2007) (22)
- UVA‐1 exposure in vivo leads to an IL‐6 surge within the skin (2017) (21)
- Essential role of an activator protein-2 (AP-2)/specificity protein 1 (Sp1) cluster in the UVB-mediated induction of the human vascular endothelial growth factor in HaCaT keratinocytes. (2003) (21)
- Alpha‐Ketoglutarate Curbs Differentiation and Induces Cell Death in Mesenchymal Stromal Precursors with Mitochondrial Dysfunction (2017) (21)
- Reduction of CD18 Promotes Expansion of Inflammatory γδ T Cells Collaborating with CD4+ T Cells in Chronic Murine Psoriasiform Dermatitis (2013) (21)
- PUVA therapy in disabling pansclerotic morphoea of children (1995) (21)
- Extracellular adherence protein of Staphylococcus aureus suppresses disease by inhibiting T-cell recruitment in a mouse model of psoriasis. (2010) (21)
- JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin (2018) (20)
- Adaptive cellular protection against UVA-1-induced lipid peroxidation in human dermal fibroblasts shows donor-to-donor variability and is glutathione dependent (2005) (20)
- Induction of manganese superoxide dismutase in human dermal fibroblasts: a UV-B-mediated paracrine mechanism with the release of epidermal interleukin 1 alpha, interleukin 1 beta, and tumor necrosis factor alpha. (2002) (20)
- CD18 in monogenic and polygenic inflammatory processes of the skin. (2006) (20)
- A Novel S100A8/A9 Induced Fingerprint of Mesenchymal Stem Cells associated with Enhanced Wound Healing (2018) (20)
- Toxic epidermal necrolysis (Lyell syndrome) following famotidine administration (1995) (19)
- Concomitant sensitization to high and low molecular‐weight heparins, heparinoid and pentosanpolysulfate (1998) (19)
- Lichenoid chronic graft-versus-host disease-like acrodermatitis induced by hydroxyurea. (2001) (19)
- Ex vivo-expanded highly pure ABCB5+ mesenchymal stromal cells as Good Manufacturing Practice-compliant autologous advanced therapy medicinal product for clinical use: process validation and first in-human data (2020) (19)
- Liver cytochrome P450 CYP1A2 is markedly inhibited by systemic but not by bath PUVA in dermatological patients (2001) (18)
- Long‐term growth arrest of PUVA‐treated fibroblasts in G2/M in the absence of p16INK4a, p21CIP1 or p53 (2003) (18)
- Successful treatment of Hailey-Hailey disease with a scanned carbon dioxide laser. (2000) (18)
- [Photodamage and photoaging--prevention and treatment]. (2005) (18)
- Methylenetetrahydrofolate reductase polymorphism associated with moderate hyperhomocysteinaemia in a patient with livedo vasculopathy: treatment with vitamin supplementation and low molecular weight heparin (2006) (18)
- Osteopontin deficiency affects imiquimod‐induced psoriasis‐like murine skin inflammation and lymphocyte distribution in skin, draining lymph nodes and spleen (2015) (18)
- Terminal B cell differentiation is skewed by deregulated interleukin‐6 secretion in β2 integrin‐deficient mice (2006) (18)
- Local and transient inhibition of p21 expression ameliorates age‐related delayed wound healing (2019) (17)
- Characterization of rapid neutrophil extracellular trap formation and its cooperation with phagocytosis in human neutrophils (2014) (17)
- Uncoupling protein 2 protects mice from aging. (2016) (16)
- MSCs rescue impaired wound healing in a murine LAD1 model by adaptive responses to low TGF‐β1 levels (2020) (16)
- Migration of a human keratinocyte cell line (HACAT) to interstitial collagen type I is mediated by the alpha 2 beta 1-integrin receptor. (1992) (16)
- Frailty index and sex-specific six-year mortality in community dwelling older people - the ActiFE Study. (2019) (16)
- T‐cell plasticity in inflammatory skin diseases – the good, the bad, and the chameleons (2015) (16)
- Anaphylaxis after Oseltamivir (Tamiflu®) therapy in a patient with sensitization to star anise and celery‐carrot‐mugwort‐spice syndrome (2008) (15)
- Isolation and identification of psoralen plus ultraviolet A (PUVA)-induced genes in human dermal fibroblasts by polymerase chain reaction-based subtractive hybridization. (2000) (15)
- Human dermal fibroblasts escape from the long-term phenocopy of senescence induced by psoralen photoactivation. (2002) (14)
- S1‐Leitlinie zur UV‐Phototherapie und Photochemotherapie (2016) (14)
- Mice with heterozygous deficiency of manganese superoxide dismutase (SOD2) have a skin immune system with features of “inflamm-aging” (2014) (14)
- [Skin aging: Molecular understanding of extrinsic and intrinsic processes]. (2015) (14)
- Localization of platelet‐derived growth factor receptor subunit expression in chronic venous leg ulcers (1995) (13)
- Lymphogranuloma venereum – A Rare Cause of Genital Ulcers in Central Europe (2004) (13)
- Discrete papular mucinosis—a rare subtype of lichen myxoedematosus (2000) (13)
- Keratoacanthoma centrifugum marginatum accompanied by extensive granulomatous foreign body reaction. (2005) (13)
- Neuronal redox imbalance results in altered energy homeostasis and early postnatal lethality (2015) (13)
- CD 18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI 3 Ks (2008) (13)
- The transcriptional response to distinct growth factors is impaired in Werner syndrome cells (2008) (13)
- Treatment of psoriatic arthritis with etanercept. (2001) (12)
- Hematopoietic Stem/Progenitor Cells Directly Contribute to Arteriosclerotic Progression via Integrin β2 (2015) (12)
- Overexpression of manganese superoxide dismutase in human dermal fibroblasts enhances the contraction of free floating collagen lattice: implications for ageing and hyperplastic scar formation (2009) (12)
- Quantitative proteome analysis of alveolar type-II cells reveals a connection of integrin receptor subunits beta 2/6 and WNT signaling. (2013) (12)
- Linking neuron and skin: matrix metalloproteinases in amyotrophic lateral sclerosis (2009) (12)
- Identification of Susceptibility Loci for Skin Disease in a Murine Psoriasis Model1 (2006) (12)
- [Allergic contact dermatitis to common ivy (Hedera helix L.)]. (2003) (11)
- Surgical management of skin cancer and trauma involving the middle third of the auricle (2018) (11)
- Molecular Role of Reactive Oxygen Species in Photoaging and Tumor Progression (1997) (10)
- Small-scale extracorporeal photopheresis for the treatment of cutaneous T-cell lymphoma: a report of 3 cases. (2005) (10)
- Corrigendum to “Heterozygous deficiency of manganese superoxide dismutase results in severe lipid peroxidation and spontaneous apoptosis in murine myocardium in vivo” [Free Radic. Biol. Med. 38:1458–1470; 2005] (2006) (10)
- Rofecoxib as an alternative in aspirin hypersensitivity (2001) (10)
- A Wnt5a-Cdc42 axis controls aging and rejuvenation of hair-follicle stem cells (2020) (10)
- A reticular variant of elastolytic giant cell granuloma (2006) (10)
- Development of IgG λ Multiple Myeloma in a Patient with Cutaneous CD30+ Anaplastic T-cell Lymphoma (1999) (10)
- Long-term growth arrest of PUVA-treated fibroblasts in G2/M in the absence of p16(INK4a) p21(CIP1) or p53. (2003) (10)
- Skin diseases in Europe. Wound healing. (2009) (9)
- Development of IgG lambda multiple myeloma in a patient with cutaneous CD30+ anaplastic T-cell lymphoma. (1999) (9)
- The Cerebro-Morphological Fingerprint of a Progeroid Syndrome: White Matter Changes Correlate with Neurological Symptoms in Xeroderma Pigmentosum (2012) (9)
- Vesicular and bullous eczema in response to intravenous immunoglobulins (IVIG) (2005) (9)
- β2 Integrin deficiency yields unconventional double‐negative T cells distinct from mature classical natural killer T cells in mice (2009) (9)
- Gene targeting for inflammatory cell adhesion molecules. (1995) (8)
- Light chain multiple myeloma with peripheral leucocytosis presenting as scleroderma amyloidosum of the Alambda-type. (1999) (8)
- Carcinoma erysipeloides of the facial skin in a patient with metastatic breast cancer (1999) (8)
- Cutaneous leukaemic infiltrations in a patient with previously undiagnosed myelodysplastic syndrome (2004) (7)
- Caffeine hypersensitivity (2002) (7)
- Chapter 6 - The negative effects of solar and artificial irradiation: photoaging of the skin, its clinical appearance and underlying mechanisms (2001) (7)
- Cockayne Syndrome-Associated CSA and CSB Mutations Impair Ribosome Biogenesis, Ribosomal Protein Stability, and Global Protein Folding (2021) (7)
- Adaptive antioxidant defence in human dermal fibroblasts (2000) (7)
- [Amelanotic polypoid malignant melanoma of the balloon cell type]. (1994) (7)
- In vitro Demonstration and Quantification of Neutrophil Extracellular Trap Formation. (2017) (7)
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- LETTER TO THE EDITOR: Management of Vemurafenib Induced Severe Arthralgia and Pyrexia in aPatient with BRAF V600E Mutated Melanoma: First Experience with aSwitch to Dabrafenib (2015) (1)
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- 357 Angiogenin released from ABCB5+ MSCs Promotes Healing of Diabetic Wounds by triggering Angiogenesis (2021) (1)
- Management of Vemurafenib Induced Severe Arthralgia and Pyrexia in a Patient with BRAF V 600 E Mutated Melanoma : First Experience with a Switch to Dabrafenib (2015) (1)
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- 076 Senescent fibroblasts enhance squamous cell carcinoma progression through secretion of Chemerin and activation of MAPK pathway (2016) (0)
- 345 Impaired Senescent Fibroblast Clearance by NK Cells During Skin Aging (2022) (0)
- New small molecular weight antioxidants and pro-oxidants control melanoma cell proliferation and spreading in vitro (2018) (0)
- A Novel S100A8/A9 Induced Fingerprint of Mesenchymal Stem Cells associated with Enhanced Wound Healing (2018) (0)
- Disease in a Murine Psoriasis Model Identification of Susceptibility Loci for Skin (2006) (0)
- Molecular mechanisms in photoageing and tumour progression (1996) (0)
- Ultraviolet-B induction of vascular endothelial growth factor in HaCaT cells is mediated by a paracrine mechanism via a SP-1 cluster - potential role in the tumor progression (1998) (0)
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- 577 Ageing in the dermal perivascular niche: ABCB5+ MSCs depend on osteopontin (2016) (0)
- Giant cell arteritis with extensive scalp necrosis: A diagnostic and therapeutic challenge (2016) (0)
- 942 Inefficient senescent fibroblast clearance in aging skin: The contribution of impaired natural killer cells (2023) (0)
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- Histone H2A deubiquitination by 2A-DUB/Mysm1 regulates critical checkpoints in early T cell development (HEM4P.226) (2014) (0)
- cockayne syndrome and disturbed protein homeostasis : p017 (2015) (0)
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- 3, 3 (cid:48) - (3, 5-DCPBC) Down-Regulates Multiple Phosphokinase Dependent Signal Transduction Pathways in Malignant Melanoma Cells through Specific Diminution of EGFR Y1086 Phosphorylation (2022) (0)
- Letter to the Editor The BRAF V600E Mutation is Not Present in All Cells of the Primary Melanoma and May Not Be Detected in All Metastatic Sites (2013) (0)
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- Heterozygous Deficiency of Manganese Superoxide Dismutase in Mice (Mn-SOD (cid:1) / (cid:2) ): A Novel Approach to Assess the Role of Oxidative Stress for the Development of Nitrate Tolerance (2005) (0)
- 223 Impaired clearance of senescent fibroblasts from aging skin: Role of compromised natural killer cells (2021) (0)
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- 736 β2 integrin-dependent activation of NOX2 oxidase in wound macrophages is required for physiological wound healing (2016) (0)
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- 071 The adaptive response of old ABCB5+ MSCs is impaired upon exposure to LPS (2023) (0)
- The migration of fibroblasts to collagen type I mediated by α 2 β 1 integrin is dependent on the action of matrix metalloproteinase (1994) (0)
- Unbalanced SOD 2 Overexpression in Senescent Fibroblasts Triggers Altered Redox Signaling and Skin Ageing (0)
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- Whether the benefit of TNF a inhibition on necrosis prevention outweighs the risk of greater susceptibility towards infection need to be determined (0)
- α-Melanocyte stimulating hormone induces fibroblast-derived collagenàse/matrix metalloproteinase-1 (1994) (0)
- A novel activity enhances promoter escape of RNA polymerase I. (2009) (0)
- Integrin 2 b Depends on Plasma Cells from Peripheral Lymph Nodes Cutting Edge: Egress of Newly Generated (2005) (0)
- Reactive oxygen species in tissue repair and its disorders (2017) (0)
- Targeting NF-{kappa}B in macrophages alleviates skin inflammation in a mouse model of psoriasis (2010) (0)
- 3, 5-DCPBC: A magic bullet for melanoma therapy (2021) (0)
- Endothelial dysfunction driven by mitochondrial reactive oxygen species – proof of concept studies in CypD −/− mice (2013) (0)
- A Novel Bis-Coumarin Targets Multiple Tyrosine Kinases of Key Signaling Pathways in Melanoma and Inhibits Melanoma Cell Survival, Proliferation, and Migration (2020) (0)
- Free Radicals and Dermal Damage in Photoaging and Photocarcinogenesis (1999) (0)
- A newly adapted pulsed-field gel electrophoresis technique allows to detect distinct types of DNA damage at low frequencies in human dermal fibroblasts upon exposure to non-toxic H2O2 concentrations. (1999) (0)
- Lipid peroxidation and enzymic antioxidants. (2000) (0)
- Ribosomal transcription is regulated by PGC-1alpha and disturbed in Huntington’s disease (2017) (0)
- Chlorophyll Derivative Carriers for Photodynamic Therapy of Squamous Cell Carcinoma (2022) (0)
- signaling RhoH is important for positive thymocyte selection and T-cell receptor (2013) (0)
- 1344 Novel human 3D skin model for skin aging research (2023) (0)
- 280 Research on skin cells unravels general mechanisms of neurological degeneration (2022) (0)
- Acquired Disorders of Elastin and Collagen (2009) (0)
- 806 A circulus vitiosus causes loss of proteostasis in Cockayne syndrome (2018) (0)
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- 061 Premature aging in Cockayne syndrome due to a failure in ribosomal biogenesis (2016) (0)
- or II PI3Ks phagocytosis of E.coli or S.aureus is regulated by Class III but not Class I CD18-dependent activation of the neutrophil NADPH oxidase during (2013) (0)
- 450 Function of H2A deubiquitinase 2A-DUB/Mysm1 in skin pigmentation and melanoma growth (2016) (0)
- Activation of Gene Expression of Collagenase and ICAM-1 by UVA Radiation and by Exposure to Singlet Oxygen (1998) (0)
- ADF Winter School—An exciting concept of the Arbeitsgemeinschaft Dermatologische Forschung to connect young scientists and clinician scientists in Dermatology at the top of Germany (2017) (0)
- TFIIH mutations can impact on translational fidelity of the ribosome (2022) (0)
- 318 A novel pathomechanism: are Cockayne syndrome and trichothiodystrophy ribosomopathies? (2019) (0)
- 543 UVA irradiation of senescence fibroblasts epigenetically unlock anti-apoptotic GDF15 expression via interleukin-6 mediated promoter demethylation in melanoma cells (2016) (0)
- Disease in a Murine Psoriasis Model Identification of Susceptibility Loci for Skin (2006) (0)
- 1413 Mesenchymal stem cells sense and shape their environment at the wound site (2018) (0)
- The versatility of transposition flaps for repair of segmental auricular defects after skin cancer surgery (2020) (0)
- Subcutaneous nodules as an adverse reaction to injections of low-molecular-weight calcium containing heparins: Calcinosis of the cutis and subcutis (2004) (0)
- Translational development of ABCB5+ dermal mesenchymal stem cells for therapeutic induction of angiogenesis in non-healing diabetic foot ulcers (2022) (0)
- Remission of Anti-laminin 332 Mucous Membrane Pemphigoid Associated with Non-small Cell Lung Cancer after Therapy with Rituximab and Intravenous Immunoglobulin (2020) (0)
- [Chronic ulceration of one side of the face]. (2006) (0)
- Psoriasis and skin diseases (WS-055) Chairpersons: Masayuki Amagai, Akira Takashima (2010) (0)
- 367 Apremilast Switches Pro-Inflammatory M1 Macrophages to Anti-Inflammatory M2 Macrophages – Transcription Factors Beyond CREB (2019) (0)
- 1422 A novel S100A8/A9 induced fingerprint of mesenchymal stem cells is associated with enhanced wound healing (2018) (0)
- Barbara Gilchrest and Jean Krutmann (eds): Skin aging (2006) (0)
- Scheie syndrome (2020) (0)
- Erythematous patches with raised edges on the face (2020) (0)
- γδ T cells and Th17 collaborate in CD18hypo PL/J psoriasiform dermatitis (P3139) (2013) (0)
- Mechanical Properties of Young and Senescence Fibroblast Cells Using Passive Microrheology (2016) (0)
- Beware when the hair turns dark again: clinical presentation and management of melanoma in situ in a giant congenital naevus on the scalp (2017) (0)
- [Painful symmetrical ankle ulcerations. A 73-year old patient with chronic myeloid leukemia]. (2004) (0)
- Disease in a Murine Psoriasis Model Identification of Susceptibility Loci for Skin (2006) (0)
- Special section: Replication stress, a threat to the nuclear and mitochondrial genome. (2018) (0)
- [Multiple quickly changing tumors on the head and trunk of a 47-year old man]. (2005) (0)
- Disease in a Murine Psoriasis Model Identification of Susceptibility Loci for Skin (2006) (0)
- [Acneiform skin eruption in patients with metastatic colorectal carcinoma]. (2006) (0)
- Hyphae Aspergillus fumigatus Response to Regulate Neutrophil Oxidase Activation in d and b Class IA Phosphoinositide 3-Kinase (2011) (0)
- INDEX (2006) (0)
- 3, 3′- (3, 5-DCPBC) Down-Regulates Multiple Phosphokinase Dependent Signal Transduction Pathways in Malignant Melanoma Cells through Specific Diminution of EGFRY1086 Phosphorylation (2022) (0)
- Phospholipid hydroperoxide glutathione peroxidase in skin - possible role in protection against ultraviolet radiation induced lipid peroxidation (1998) (0)
- [Multiple hyperpigmented facial plaques]. (2005) (0)
- 1477 Sodium butyrate promotes diabetic tissue repair through resetting the epigenetic machinery of macrophages (2023) (0)
- Targeting NF‐κB in macrophages alleviates skin inflammation in a mouse model of psoriasis (2010) (0)
- JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin (2018) (0)
- Modeling trauma in rats: similarities to humans and potential pitfalls to consider (2019) (0)
- Mechanismen der zellulären Migration (1994) (0)
- Mitochondrial deletions in different skin compartments of young and aged wildtype mice (2011) (0)
- Acquired Disorders of Collagen and Elastin (2020) (0)
- il-1 signalling is up-regulated in chronic venous leg ulcers and represents a therapeutic target that is counteracted by dermal Abcb5+ mesenchymal stem cells via secretion of interleukin-1 receptor antagonist : p054 (2015) (0)
- Progressive decrease in number and change in niche preference of theABCB5+mesenchymal stem cell subset in the skin during aging (2010) (0)
- 334 Pulling the Trigger on Tissue Decline and Rejuvenation in the connective tissue - A Novel Role for JunB (2021) (0)
- 223 A DNA-repair independent pathomechanism in Cockayne syndrome (2017) (0)
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