Karl Mechtler
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Karl Mechtlerchemistry Degrees
Chemistry
#4064
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#5124
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Analytical Chemistry
#166
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#173
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Physical Chemistry
#600
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#652
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Karl Mechtlerbiology Degrees
Biology
#11152
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#14529
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Biochemistry
#1814
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#1952
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Chemistry Biology
Karl Mechtler's Degrees
- PhD Chemistry University of Vienna
- Bachelors Chemistry University of Vienna
Why Is Karl Mechtler Influential?
(Suggest an Edit or Addition)Karl Mechtler's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins (2001) (2844)
- Regulation of chromatin structure by site-specific histone H3 methyltransferases (2000) (2820)
- Loss of the Suv39h Histone Methyltransferases Impairs Mammalian Heterochromatin and Genome Stability (2001) (1673)
- Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. (2003) (1160)
- Reversal of H3K9me2 by a small-molecule inhibitor for the G9a histone methyltransferase. (2007) (751)
- Universal and confident phosphorylation site localization using phosphoRS. (2011) (709)
- The influence of endosome-disruptive peptides on gene transfer using synthetic virus-like gene transfer systems. (1994) (644)
- BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals (2008) (619)
- The Par complex directs asymmetric cell division by phosphorylating the cytoskeletal protein Lgl (2003) (598)
- Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery. (1996) (583)
- Wapl Controls the Dynamic Association of Cohesin with Chromatin (2006) (580)
- The size of DNA/transferrin-PEI complexes is an important factor for gene expression in cultured cells (1998) (570)
- Asymmetric Segregation of the Tumor Suppressor Brat Regulates Self-Renewal in Drosophila Neural Stem Cells (2006) (517)
- Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I (2006) (495)
- Systematic Analysis of Human Protein Complexes Identifies Chromosome Segregation Proteins (2010) (493)
- Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes. (1992) (483)
- Dissociation of Cohesin from Chromosome Arms and Loss of Arm Cohesion during Early Mitosis Depends on Phosphorylation of SA2 (2005) (472)
- Mitotic regulation of the human anaphase‐promoting complex by phosphorylation (2003) (437)
- Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing (2006) (419)
- Phosphorylation of the Cohesin Subunit Scc1 by Polo/Cdc5 Kinase Regulates Sister Chromatid Separation in Yeast (2001) (404)
- Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells. (2006) (388)
- Sororin Mediates Sister Chromatid Cohesion by Antagonizing Wapl (2010) (360)
- MS Amanda, a Universal Identification Algorithm Optimized for High Accuracy Tandem Mass Spectra (2014) (337)
- Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. (2009) (323)
- Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels. (1990) (320)
- Gene transfer into hepatocytes using asialoglycoprotein receptor mediated endocytosis of DNA complexed with an artificial tetra-antennary galactose ligand. (1992) (313)
- Live-cell imaging RNAi screen identifies PP2A–B55α and importin-β1 as key mitotic exit regulators in human cells (2010) (312)
- ATP Hydrolysis Is Required for Cohesin's Association with Chromosomes (2003) (292)
- Aurora A phosphorylation of TACC3/maskin is required for centrosome-dependent microtubule assembly in mitosis (2005) (272)
- An in vivo RNAi assay identifies major genetic and cellular requirements for primary piRNA biogenesis in Drosophila (2010) (264)
- Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage (2008) (249)
- Eco1 Is a Novel Acetyltransferase that Can Acetylate Proteins Involved in Cohesion (2002) (245)
- Structure of the Anaphase-Promoting Complex/Cyclosome Interacting with a Mitotic Checkpoint Complex (2009) (245)
- Sororin Is Required for Stable Binding of Cohesin to Chromatin and for Sister Chromatid Cohesion in Interphase (2007) (233)
- Rec8 Phosphorylation by Casein Kinase 1 and Cdc7-Dbf4 Kinase Regulates Cohesin Cleavage by Separase during Meiosis (2010) (191)
- Monopolar Attachment of Sister Kinetochores at Meiosis I Requires Casein Kinase 1 (2006) (189)
- HSPC117 Is the Essential Subunit of a Human tRNA Splicing Ligase Complex (2011) (189)
- CENP-T proteins are conserved centromere receptors of the Ndc80 complex (2012) (181)
- A systematic analysis of Drosophila TUDOR domain‐containing proteins identifies Vreteno and the Tdrd12 family as essential primary piRNA pathway factors (2011) (180)
- Peptide Labeling with Isobaric Tags Yields Higher Identification Rates Using iTRAQ 4-Plex Compared to TMT 6-Plex and iTRAQ 8-Plex on LTQ Orbitrap (2010) (179)
- Spatial Exclusivity Combined with Positive and Negative Selection of Phosphorylation Motifs Is the Basis for Context-Dependent Mitotic Signaling (2011) (171)
- 14‐3‐3 Proteins recognize a histone code at histone H3 and are required for transcriptional activation (2008) (165)
- Charting the molecular network of the drug target Bcr-Abl (2009) (161)
- High precision quantitative proteomics using iTRAQ on an LTQ Orbitrap: a new mass spectrometric method combining the benefits of all. (2009) (159)
- A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila (2010) (156)
- McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits the Heat-Shock Regulator CtsR (2009) (155)
- Quantitative Phosphoproteomics of the Ataxia Telangiectasia-Mutated (ATM) and Ataxia Telangiectasia-Mutated and Rad3-related (ATR) Dependent DNA Damage Response in Arabidopsis thaliana* (2015) (153)
- Epigenetic Temporal Control of Mouse Hox Genes in Vivo (2009) (151)
- Inter-Homolog Crossing-Over and Synapsis in Arabidopsis Meiosis Are Dependent on the Chromosome Axis Protein AtASY3 (2012) (149)
- Unambiguous Phosphosite Localization using Electron-Transfer/Higher-Energy Collision Dissociation (EThcD) (2013) (144)
- Topology and Organization of the Salmonella typhimurium Type III Secretion Needle Complex Components (2010) (139)
- A structural basis for kinetochore recruitment of the Ndc80 complex via two distinct centromere receptors (2013) (136)
- Arginine phosphorylation marks proteins for degradation by a Clp protease (2016) (136)
- Ultra-high-pressure RPLC hyphenated to an LTQ-Orbitrap Velos reveals a linear relation between peak capacity and number of identified peptides. (2011) (135)
- Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin (2013) (133)
- DNA-binding transferrin conjugates as functional gene-delivery agents: synthesis by linkage of polylysine or ethidium homodimer to the transferrin carbohydrate moiety. (1991) (132)
- Interplay of PDZ and protease domain of DegP ensures efficient elimination of misfolded proteins (2008) (130)
- General statistical modeling of data from protein relative expression isobaric tags. (2011) (130)
- APC15 mediates CDC20 autoubiquitylation by APC/CMCC and disassembly of the mitotic checkpoint complex (2012) (130)
- Phosphoproteomics strategies for the functional analysis of signal transduction (2006) (127)
- Phosphoregulation of the budding yeast EB1 homologue Bim1p by Aurora/Ipl1p (2009) (122)
- Polysialylation controls dendritic cell trafficking by regulating chemokine recognition (2016) (119)
- Receptor-mediated gene transfer into human T lymphocytes via binding of DNA/CD3 antibody particles to the CD3 T cell receptor complex. (1995) (116)
- Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes (2007) (115)
- Mechanism of APC/CCDC20 activation by mitotic phosphorylation (2016) (109)
- Titanium dioxide as a chemo-affinity solid phase in offline phosphopeptide chromatography prior to HPLC-MS/MS analysis (2007) (108)
- Raman microspectroscopy reveals long‐term extracellular activity of chlamydiae (2010) (106)
- Analysis of protein mixtures from whole-cell extracts by single-run nanoLC-MS/MS using ultralong gradients (2012) (104)
- Generation and characterization of methyl-lysine histone antibodies. (2004) (102)
- Identification of a Subunit of a Novel Kleisin-β/SMC Complex as a Potential Substrate of Protein Phosphatase 2A (2003) (102)
- Afamin is a novel human vitamin E-binding glycoprotein characterization and in vitro expression. (2005) (101)
- Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels. (2003) (101)
- Systematic Phosphorylation Analysis of Human Mitotic Protein Complexes (2011) (98)
- Comparative glycoproteomics of stem cells identifies new players in ricin toxicity (2017) (93)
- A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A (2014) (89)
- Arabidopsis PCH2 Mediates Meiotic Chromosome Remodeling and Maturation of Crossovers (2015) (85)
- HPLC techniques for proteomics analysis--a short overview of latest developments. (2006) (85)
- Regulation of Gene Expression through a Transcriptional Repressor that Senses Acyl-Chain Length in Membrane Phospholipids (2014) (85)
- First Community-Wide, Comparative Cross-Linking Mass Spectrometry Study (2019) (80)
- ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL (2019) (79)
- Influence of membrane-active peptides on lipospermine/DNA complex mediated gene transfer. (1997) (78)
- Drosophila CPEB Orb2A Mediates Memory Independent of Its RNA-Binding Domain (2012) (77)
- Casein kinase 1 is required for efficient removal of Rec8 during meiosis I (2010) (72)
- Chemical cross-linking and high-performance Fourier transform ion cyclotron resonance mass spectrometry for protein interaction analysis: application to a calmodulin/target peptide complex. (2005) (69)
- Anion-Exchange Chromatography of Phosphopeptides: Weak Anion Exchange versus Strong Anion Exchange and Anion-Exchange Chromatography versus Electrostatic Repulsion–Hydrophilic Interaction Chromatography (2015) (69)
- Quantitative Phospho-proteomics to Investigate the Polo-like Kinase 1-Dependent Phospho-proteome* (2011) (68)
- Preventing carryover of peptides and proteins in nano LC-MS separations. (2009) (68)
- Isotope-labeled cross-linkers and fourier transform ion cyclotron resonance mass spectrometry for structural analysis of a protein/peptide complex (2006) (68)
- The AAA-ATPase molecular chaperone Cdc48/p97 disassembles sumoylated centromeres, decondenses heterochromatin, and activates ribosomal RNA genes (2014) (67)
- Quantitative Phosphoproteomics Reveals the Role of Protein Arginine Phosphorylation in the Bacterial Stress Response* (2013) (67)
- Probing the phosphoproteome of HeLa cells using nanocast metal oxide microspheres for phosphopeptide enrichment. (2010) (64)
- A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress (2020) (61)
- Tandem affinity purification of functional TAP-tagged proteins from human cells (2007) (60)
- Cell-free tumor antigen peptide-based cancer vaccines. (1997) (59)
- The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation (2019) (59)
- Glycerol and polylysine synergize in their ability to rupture vesicular membranes: a mechanism for increased transferrin-polylysine-mediated gene transfer. (1997) (58)
- Automated, on‐line two‐dimensional nano liquid chromatography tandem mass spectrometry for rapid analysis of complex protein digests (2004) (57)
- An improved method for tracking and reducing the void volume in nano HPLC–MS with micro trapping columns (2003) (57)
- GENE TRANSFER MEDIATED BY INFLUENZA VIRUS PEPTIDES : THE ROLE OF PEPTIDE SEQUENCES (1997) (56)
- Transloading of tumor antigen-derived peptides into antigen-presenting cells. (1997) (55)
- A Dam1-based artificial kinetochore is sufficient to promote chromosome segregation in budding yeast (2009) (53)
- AMPK leads to phosphorylation of the transcription factor Nrf2, tuning transactivation of selected target genes (2019) (52)
- H3S28 phosphorylation is a hallmark of the transcriptional response to cellular stress (2014) (51)
- Improved Precision of iTRAQ and TMT Quantification by an Axial Extraction Field in an Orbitrap HCD Cell (2011) (51)
- MASPECTRAS: a platform for management and analysis of proteomics LC-MS/MS data (2007) (50)
- Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense (2014) (50)
- SIMPATIQCO: A Server-Based Software Suite Which Facilitates Monitoring the Time Course of LC–MS Performance Metrics on Orbitrap Instruments (2012) (49)
- apQuant: Accurate Label-Free Quantification by Quality Filtering. (2018) (49)
- CCAN Assembly Configures Composite Binding Interfaces to Promote Cross-Linking of Ndc80 Complexes at the Kinetochore (2016) (47)
- A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes (2019) (47)
- MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation (2019) (47)
- Peptide Orientation Affects Selectivity in Ion-Exchange Chromatography (2010) (46)
- CharmeRT: Boosting Peptide Identifications by Chimeric Spectra Identification and Retention Time Prediction (2018) (46)
- Cleaning of raw peptide MS/MS spectra: Improved protein identification following deconvolution of multiply charged peaks, isotope clusters, and removal of background noise (2006) (46)
- Molecular basis for cytoplasmic RNA surveillance by uridylation‐triggered decay in Drosophila (2016) (46)
- qcML: An Exchange Format for Quality Control Metrics from Mass Spectrometry Experiments* (2014) (45)
- Stoichiometry determination of the MP1-p14 complex using a novel and cost-efficient method to produce an equimolar mixture of standard peptides. (2009) (45)
- The 20S proteasome isolated from Alzheimer’s disease brain shows post‐translational modifications but unchanged proteolytic activity (2007) (45)
- Transcriptome and proteome quantification of a tumor model provides novel insights into post‐transcriptional gene regulation (2013) (45)
- A DEK Domain-Containing Protein Modulates Chromatin Structure and Function in Arabidopsis[W][OPEN] (2014) (44)
- Laser microsurgery provides evidence for merotelic kinetochore attachments in fission yeast cells lacking Pcs1 or Clr4 (2010) (44)
- Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data (2018) (44)
- Annexin A2/P11 interaction: New insights into annexin A2 tetramer structure by chemical crosslinking, high‐resolution mass spectrometry, and computational modeling (2007) (44)
- Affinity proteomics reveals extensive phosphorylation of the Brassica chromosome axis protein ASY1 and a network of associated proteins at prophase I of meiosis (2017) (42)
- Recruitment of PRC 1 function at the initiation of X inactivation independent of PRC 2 and silencing (2013) (41)
- Chasing Phosphoarginine Proteins: Development of a Selective Enrichment Method Using a Phosphatase Trap* (2014) (40)
- A Chemical Proteomics Approach to Phosphatidylinositol 3-Kinase Signaling in Macrophages*S (2007) (39)
- Phosphoproteomics with Activated Ion Electron Transfer Dissociation. (2017) (39)
- The replicative helicase MCM recruits cohesin acetyltransferase ESCO2 to mediate centromeric sister chromatid cohesion (2018) (38)
- Absolute quantification of cohesin, CTCF and their regulators in human cells (2019) (38)
- Carbohydrate receptor-mediated gene transfer to human T leukaemic cells. (1994) (38)
- Improved Sensitivity in Low-Input Proteomics Using Micropillar Array-Based Chromatography (2019) (37)
- Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation (2015) (37)
- N-terminal β-strand underpins biochemical specialization of an ATG8 isoform (2018) (36)
- An improved strategy for tandem affinity purification‐tagging of Schizosaccharomyces pombe genes (2009) (36)
- Optimized Nonlinear Gradients for Reversed-Phase Liquid Chromatography in Shotgun Proteomics (2013) (36)
- The biophysical, molecular, and anatomical landscape of pigeon CRY4: A candidate light-based quantal magnetosensor (2020) (35)
- A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress. (2020) (34)
- Optimized Fragmentation Improves the Identification of Peptides Cross-Linked by MS-Cleavable Reagents. (2019) (34)
- Studying the fragmentation behavior of peptides with arginine phosphorylation and its influence on phospho‐site localization (2013) (34)
- A new acid mix enhances phosphopeptide enrichment on titanium- and zirconium dioxide for mapping of phosphorylation sites on protein complexes. (2010) (33)
- LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma (2020) (33)
- Spatiotemporal Regulation of Ipl1/Aurora Activity by Direct Cdk1 Phosphorylation (2012) (33)
- Enhanced detection and identification of multiply phosphorylated peptides using TiO2 enrichment in combination with MALDI TOF/TOF MS (2008) (32)
- Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1. (2015) (32)
- An automated workflow for multiplexed single-cell proteomics sample preparation at unprecedented sensitivity (2021) (32)
- Autophagy mediates temporary reprogramming and dedifferentiation in plant somatic cells (2019) (32)
- A novel non-canonical PIP-box mediates PARG interaction with PCNA (2017) (31)
- Quality control in LC‐MS/MS (2011) (31)
- Cleavable Cross-Linkers and Mass Spectrometry for the Ultimate Task of Profiling Protein–Protein Interaction Networks in Vivo (2020) (30)
- Interlaboratory studies and initiatives developing standards for proteomics (2013) (30)
- AKIRIN2 controls the nuclear import of proteasomes in vertebrates (2021) (29)
- Proteins recognize a histone code at histone H 3 and are required for transcriptional activation (2007) (29)
- Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans (2018) (29)
- Linear ubiquitination by LUBEL has a role in Drosophila heat stress response (2016) (29)
- The rise of single‐cell proteomics (2021) (28)
- SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation (2016) (28)
- Yeast Protein Phosphatase 2A-Cdc55 Regulates the Transcriptional Response to Hyperosmolarity Stress by Regulating Msn2 and Msn4 Chromatin Recruitment (2012) (27)
- QIKS – Quantitative identification of kinase substrates (2010) (27)
- Rio1 promotes rDNA stability and downregulates RNA polymerase I to ensure rDNA segregation (2015) (27)
- An innovative method to study target protein-drug interactions by mass spectrometry. (2009) (27)
- Lesson from the Stoichiometry Determination of the Cohesin Complex: A Short Protease Mediated Elution Increases the Recovery from Cross-Linked Antibody-Conjugated Beads (2010) (26)
- Ultrasensitive NanoLC-MS of Subnanogram Protein Samples Using Second Generation Micropillar Array LC Technology with Orbitrap Exploris 480 and FAIMS PRO (2021) (25)
- Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry. (2020) (25)
- Development and performance evaluation of an ultralow flow nanoliquid chromatography‐tandem mass spectrometry set‐up (2014) (24)
- Deep and precise quantification of the mouse synaptosomal proteome reveals substantial remodeling during postnatal maturation. (2014) (23)
- Quantitative Phosphoproteomics Reveals the Role of Protein Arginine Phosphorylation in the Bacterial Stress Response. (2014) (23)
- Optimizing the performance of tin dioxide microspheres for phosphopeptide enrichment. (2009) (22)
- Differential cofactor dependencies define distinct types of human enhancers (2022) (22)
- The H3 histone chaperone NASPSIM 3 escorts CenH3 in Arabidopsis. (2019) (22)
- Absolute quantification of cohesin, CTCF and their regulators in human cells. (2019) (22)
- Structure of McsB, a protein kinase for regulated arginine phosphorylation (2019) (22)
- From an electrophoretic mobility shift assay to isolated transcription factors: a fast genomic-proteomic approach (2010) (21)
- A vital sugar code for ricin toxicity (2017) (21)
- Application of different fragmentation techniques for the analysis of phosphopeptides using a hybrid linear ion trap-FTICR mass spectrometer. (2006) (21)
- The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains (2021) (21)
- Analysis of PNGase F‐Resistant N‐Glycopeptides Using SugarQb for Proteome Discoverer 2.1 Reveals Cryptic Substrate Specificities (2018) (20)
- Proteomic analysis reveals a virtually complete set of proteins for translation and energy generation in elementary bodies of the amoeba symbiont Protochlamydia amoebophila (2011) (19)
- Transloading of tumor cells with foreign major histocompatibility complex class I peptide ligand: a novel general strategy for the generation of potent cancer vaccines. (1996) (19)
- Reducing the haystack to find the needle: improved protein identification after fast elimination of non-interpretable peptide MS/MS spectra and noise reduction (2010) (18)
- Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex (2021) (17)
- Identification of cell cycle-dependent phosphorylation sites on the anaphase-promoting complex/cyclosome by mass spectrometry. (2005) (17)
- UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins (2018) (16)
- ANGEL2 is a member of the CCR4 family of deadenylases with 2′,3′-cyclic phosphatase activity (2020) (15)
- MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells (2021) (15)
- Proteomic analysis of the outer membrane of Protochlamydia amoebophila elementary bodies (2010) (14)
- Quantitative Accuracy and Precision in Multiplexed Single-Cell Proteomics (2021) (14)
- Characterisation of the rubber elongation factor from ammoniated latex by electrophoresis and mass spectrometry. (2000) (13)
- Urinary neprilysin in the critically ill patient (2017) (13)
- Comparative Proteome Signatures of Trace Samples by Multiplexed Data-Independent Acquisition (2021) (13)
- Phosphoregulation of the budding yeast EB 1 homologue Bim 1 p by Aurora / Ipl 1 p (13)
- Global Analysis of Muscle-specific Kinase Signaling by Quantitative Phosphoproteomics* (2014) (13)
- APC15 mediates CDC20 auto-ubiquitylation by APC/CMCC and MCC disassembly (2012) (13)
- MS Annika: A New Cross-Linking Search Engine (2021) (11)
- Heat shock protein 70 (Hsp70) subtype expression in neuroendocrine tissue and identification of a neuroendocrine tumour-specific Hsp70 truncation. (2004) (11)
- Fast and Highly Efficient Affinity Enrichment of Azide-A-DSBSO Cross-Linked Peptides (2019) (11)
- A Combination of CRISPR/Cas9 and Standardized RNAi as a Versatile Platform for the Characterization of Gene Function (2016) (10)
- Spectral Clustering Improves Label-Free Quantification of Low-Abundant Proteins (2019) (10)
- Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts (2010) (10)
- Improving Phosphopeptide/Protein Identification Using a New Data Mining Framework for MS/MS Spectra Preprocessing (2009) (10)
- Musk Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase Loop (2016) (9)
- PhoStar: Identifying Tandem Mass Spectra of Phosphorylated Peptides before Database Search. (2018) (9)
- Proceedings of the EuBIC Winter School 2017. (2017) (9)
- PHF3 regulates neuronal gene expression through the Pol II CTD reader domain SPOC (2020) (9)
- Zebrafish Ski7 tunes RNA levels during the oocyte-to-embryo transition (2020) (9)
- Analysis of meiotic protein complexes from Arabidopsis and Brassica using affinity-based proteomics. (2013) (8)
- Crosstalk between H2A variant-specific modifications impacts vital cell functions (2021) (7)
- TORC1 signaling exerts spatial control over microtubule dynamics by promoting nuclear export of Stu2 (2017) (7)
- A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse (2020) (7)
- Wide Window Acquisition and AI-based data analysis to reach deep proteome coverage for a wide sample range, including single cell proteomic inputs (2022) (6)
- Mimicked synthetic ribosomal protein complex for benchmarking crosslinking mass spectrometry workflows (2022) (6)
- Site‐specific ubiquitination of the E3 ligase HOIP regulates apoptosis and immune signaling (2020) (5)
- Erratum: BAC TransgeneOmics: A high-throughput method for exploration of protein function in mammals (Nature Methods (2008) vol. 5 (409-415)) (2008) (5)
- The linear ubiquitin chain assembly complex generates heterotypic ubiquitin chains (2020) (5)
- MS Amanda 2.0: Advancements in the standalone implementation (2021) (5)
- Intron excision from precursor tRNA molecules in mammalian cells requires ATP hydrolysis and phosphorylation of tRNA-splicing endonuclease components. (2013) (5)
- COMPLEMENT ACTIVATION BY POLYLYSINE-DNA COMPLEXES (1996) (5)
- Robust and Easy-to-Use One-Pot Workflow for Label-Free Single-Cell Proteomics (2022) (4)
- Cdc4 phospho-degrons allow differential regulation of Ame1CENP-U protein stability across the cell cycle (2021) (4)
- A molecular network of conserved factors keeps ribosomes dormant in the egg (2021) (4)
- Bacterial-type ferroxidase tunes iron-dependent phosphate sensing during Arabidopsis root development (2022) (4)
- Ultra-sensitive nanoLC-MS of sub nanogram protein samples using second generation micro pillar array LC technology with Orbitrap Exploris 480 and FAIMS PRO (2021) (4)
- Towards Increased Reliability, Transparency and Accessibility in Crosslinking Mass Spectrometry (2020) (3)
- Altered Mascot search results by changing the m/z range of MS/MS spectra: analysis and potential applications (2011) (3)
- Quality standards in proteomics research facilities (2021) (3)
- GSK3‐mediated phosphorylation of DEK3 regulates chromatin accessibility and stress tolerance in Arabidopsis (2021) (3)
- The expression, localisation and interactome of pigeon CRY2 (2021) (3)
- Cross-linking/Mass Spectrometry: A Community-Wide, Comparative Study Towards Establishing Best Practice Guidelines (2018) (3)
- Receptor-mediated gene delivery into mammalian cells (1994) (2)
- A structural basis for kinetochore recruitment of the Ndc 80 complex via two distinct receptors (2012) (2)
- Structural analysis of urinary light chains and proteomic analysis of hyaline tubular casts in light chain associated kidney disorders (2019) (2)
- Preparation of HeLa peptides for LC-MS (2012) (2)
- Label-Free Single Cell Proteomics Utilizing Ultrafast LC and MS Instrumentation: A Valuable Complementary Technique to Multiplexing. (2023) (2)
- Mutations that prevent methylation of cohesin render sensitivity to DNA damage in S. pombe (2018) (2)
- Deep Proteome Profiling with Reduced Carryover Using Superficially Porous Microfabricated nanoLC Columns (2022) (2)
- Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers (2022) (2)
- Site-specific ubiquitination of the E3 ligase HOIP regulates cell death and immune signaling (2019) (2)
- 3DSpectra: A 3-dimensional quantification algorithm for LC-MS labeled profile data. (2015) (2)
- Improved Sensitivity in Low-Input Proteomics using Micro-Pillar Array-based Chromatography (2019) (2)
- A novel approach to immunoapheresis of C3a/C3 and proteomic identification of associates (2019) (2)
- Author Correction: Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data (2018) (2)
- Optimized Quantification and Identification on LTQ Orbitrap using Peptide Labeling with Isobaric Tags. (2010) (1)
- Transcriptome and proteome quantification of a tumor model provides novel insights into post‐transcriptional gene regulation (2013) (1)
- Optimized fragmentation improves the identification of peptides cross-linked using MS-cleavable reagents (2018) (1)
- SIRT 2 regulates nuclear envelope reassembly via ANKLE 2 deacetylation (2016) (1)
- A Symbolic Regression Based Scoring System Improving Peptide Identifications for MS Amanda (2015) (1)
- Corrigendum: MuSK Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase Loop (2016) (1)
- Publisher Correction: Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans (2018) (1)
- Author response: Absolute quantification of cohesin, CTCF and their regulators in human cells (2019) (1)
- Deep Single-Shot NanoLC-MS Proteome Profiling with a 1500 Bar UHPLC System, Long Fully Porous Columns, and HRAM MS (2022) (1)
- Analysis of 8000 proteins and reduced carry over significantly increase the throughput of single-shot proteomics (2021) (1)
- Bacterial-type plant ferroxidases tune local phosphate sensing in root development (2021) (1)
- Cryo-EM structure of the plant 26S proteasome (2022) (1)
- MS Ana: Improving Sensitivity in Peptide Identification with Spectral Library Search (2023) (1)
- Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans (2018) (0)
- A synthetic peptide library for benchmarking crosslinking-mass spectrometry search engines for proteins and protein complexes (2020) (0)
- A high-sensitivity low-nanoflow LC-MS configuration for high-throughput sample-limited proteomics (2023) (0)
- Author response: Cdc4 phospho-degrons allow differential regulation of Ame1CENP-U protein stability across the cell cycle (2021) (0)
- The H3 histone chaperone NASP escorts CenH3 in Arabidopsis (2019) (0)
- 735 The transcription factor c-Jun/AP-1 is a central regulator of hepatocyte survival (2006) (0)
- UFD-2 is an adaptor-assisted E3 ligase targeting unfolded proteins (2018) (0)
- Correction to "Comprehensive Cross-Linking Mass Spectrometry Reveals Parallel Orientation and Flexible Conformations of Plant HOP2-MND1". (2016) (0)
- The Fgf/Erf/NCoR1/2 repressive axis controls trophoblast cell fate. (2023) (0)
- Erratum: Lymphatic microvessels in the rat remnant kidney model of renal fibrosis: Aminopeptidase p and podoplanin are discriminatory markers for endothelial cells of blood and lymphatic vessels. (Journal of the American Society of Nephrology (2003) 14 (1981-1989)) (2019) (0)
- proteoCHIP & cellenONE taking multiplexed single cell proteomics sample preparation to the next level (2021) (0)
- Call for Candidates for the 2016 EuPA Young Investigator Prize (PhD) (2016) (0)
- Differentially accessible Cdc4 phospho-degrons regulate Ctf19CCAN kinetochore subunit stability in mitosis (2021) (0)
- Integrated transcriptome and proteome analysis reveals posttranscriptional regulation of ribosomal genes in human brain organoids (2023) (0)
- Multiplexed detection of SARS-CoV-2 and other respiratory infections in high throughput by SARSeq (2021) (0)
- Genes in Vivo Hox Epigenetic Temporal Control of Mouse (2012) (0)
- Absolute Quantification and Stoichiometry Determination of Protein Complexes; A Novel and Cost-efficient Method to Produce Exact Equimolar Mixture of Standard Peptides. (2010) (0)
- Author response: The linear ubiquitin chain assembly complex (LUBAC) generates heterotypic ubiquitin chains (2021) (0)
- Author Correction: Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data (2018) (0)
- Dual localization of ZYP1 and recombination pathway proteins in wild type Arabidopsis and Atpch2-1 meiotic nuclei at mid/late prophase. (2015) (0)
- enrichment method using a phosphatase trap (2014) (0)
- MTHFD1 interaction with BRD4 links folate metabolism to transcriptional regulation (2019) (0)
- Functionally distinct promoter classes initiate transcription via different mechanisms reflected in focused versus dispersed initiation patterns (2022) (0)
- Reply to ‘Defining distance restraints in HADDOCK’ (2018) (0)
- A causal model of ion interference enables assessment and correction of ratio compression in multiplex proteomics (2022) (0)
- ABRF-sPRG 2011–2012 Study: Development and Characterization of a Comprehensive Standard for Analysis of Post-translational Modifications Followed by Evaluation of the Standard by Study Participants. (2012) (0)
- cellenONE ® : all-in-one solution for single cell proteomics using LC-MS/MS sample preparation (2020) (0)
- Recombination frequency and chiasma distribution in Atpch2-1. (2015) (0)
- ABRF-sPRG2011 Study: Development of a Comprehensive Standard for Analysis of Post-Translational Modifications. (2011) (0)
- Regulation of p53 activity by the lysine demethylase KDM7A (2015) (0)
- Recombination defects in hhp1-as hhp2∆ and rec11 phosphorylation-site mutants resemble those in rec8∆ and rec11∆ mutants, and phosphomimetic rec11 mutation partially suppresses hhp1-as hhp2∆ . (2015) (0)
- MTHFD1 is a genetic interactor of BRD4 and links folate metabolism to transcriptional regulation (2018) (0)
- Scheme for dual action of casein kinase 1 (Hhp) on cohesin subunits to regulate meiotic chromosome segregation via Rec8 phosphorylation and to promote linear element formation, meiotic DSB formation, and recombination via Rec11 phosphorylation. (2015) (0)
- Author response: A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress (2020) (0)
- Chemically defined, cell-free cancer vaccines: use of tumor antigen-derived peptides or polyepitope proteins for vaccination (1998) (0)
- Rec11 is phosphorylated during meiosis, at least partially dependent on Hhp. (2015) (0)
- Correction: Casein Kinase 1 and Phosphorylation of Cohesin Subunit Rec11 (SA3) Promote Meiotic Recombination through Linear Element Formation (2015) (0)
- Integrated transcriptome and proteome analysis in human brain organoids reveals posttranscriptional regulation of ribosomal genes (2022) (0)
- hhp and rec11-10A mutations reduce the number and intensity of foci of linear element proteins. (2015) (0)
- Fuhrmann the Heat-Shock Regulator CtsR McsB Is a Protein Arginine Kinase That Phosphorylates and Inhibits (2013) (0)
- Differential cofactor dependencies define distinct types of human enhancers (2022) (0)
- Reply to ‘Defining distance restraints in HADDOCK’ (2018) (0)
- Publisher Correction: Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans (2018) (0)
- Urinary Collectrin (TMEM27) as Novel Marker for Acute Kidney Injury (2022) (0)
- TurboID-based proteomic profiling of meiotic chromosome axes in Arabidopsis thaliana (2023) (0)
- Estimating Actual False Localization Rates for Large-Scale Proteomics Datasets (2014) (0)
- Structural characterization of the linear ubiquitin chain assembly complex (2019) (0)
- Linear ubiquitination by LUBEL plays a critical role in Drosophila heat stress response (2016) (0)
- MASPECTRAS:Web-based System for Storage, Retrieval, and Analysis of Proteomic LC MS/MS Data. (2005) (0)
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What Schools Are Affiliated With Karl Mechtler?
Karl Mechtler is affiliated with the following schools:
