Karla Kirkegaard
#85,521
Most Influential Person Now
American geneticist and microbiologist
Karla Kirkegaard's AcademicInfluence.com Rankings
Karla Kirkegaardbiology Degrees
Biology
#6365
World Rank
#9062
Historical Rank
#2056
USA Rank
Microbiology
#836
World Rank
#918
Historical Rank
#149
USA Rank
Genetics
#1566
World Rank
#1671
Historical Rank
#296
USA Rank
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Biology
Karla Kirkegaard's Degrees
- PhD Microbiology University of California, San Francisco
- Bachelors Biology University of California, Berkeley
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Why Is Karla Kirkegaard Influential?
(Suggest an Edit or Addition)According to Wikipedia, Karla Kirkegaard is the Violetta L. Horton Research Professor of genetics at the Stanford University School of Medicine. She was the chair of the Department of Microbiology and Immunology from 2006 to 2010. She is an elected member of the American Academy of Arts and Sciences and the National Academy of Sciences. Her research focuses on virology.
Karla Kirkegaard's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (2012) (2913)
- Subversion of Cellular Autophagosomal Machinery by RNA Viruses (2005) (793)
- The NeST Long ncRNA Controls Microbial Susceptibility and Epigenetic Activation of the Interferon-γ Locus (2013) (582)
- Remodeling the Endoplasmic Reticulum by Poliovirus Infection and by Individual Viral Proteins: an Autophagy-Like Origin for Virus-Induced Vesicles (2000) (517)
- The mechanism of RNA recombination in poliovirus (1986) (483)
- Cellular autophagy: surrender, avoidance and subversion by microorganisms (2004) (471)
- Cellular origin and ultrastructure of membranes induced during poliovirus infection (1996) (412)
- A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity (2003) (378)
- Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A. (1995) (362)
- Increased Fidelity Reduces Poliovirus Fitness and Virulence under Selective Pressure in Mice (2005) (359)
- Neuron‐to‐neuron transmission of α‐synuclein fibrils through axonal transport (2012) (286)
- Six RNA Viruses and Forty-One Hosts: Viral Small RNAs and Modulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems (2010) (254)
- Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA. (1980) (239)
- Functional Coupling between Replication and Packaging of Poliovirus Replicon RNA (1999) (211)
- Coupling between genome translation and replication in an RNA virus. (1994) (210)
- Inhibition of poliovirus RNA synthesis by brefeldin A (1992) (205)
- Inhibition of endoplasmic reticulum-to-Golgi traffic by poliovirus protein 3A: genetic and ultrastructural analysis (1997) (193)
- Nonlytic viral spread enhanced by autophagy components (2014) (192)
- Improved method for detecting poliovirus negative strands used to demonstrate specificity of positive-strand encapsidation and the ratio of positive to negative strands in infected cells (1991) (183)
- Poliovirus 3A Protein Limits Interleukin-6 (IL-6), IL-8, and Beta Interferon Secretion during Viral Infection (2001) (177)
- Human protein Sam68 relocalization and interaction with poliovirus RNA polymerase in infected cells. (1996) (168)
- MHC I-dependent antigen presentation is inhibited by poliovirus protein 3A. (2000) (162)
- Modification of Cellular Autophagy Protein LC3 by Poliovirus (2007) (161)
- Bacterial DNA topoisomerase I can relax positively supercoiled DNA containing a single-stranded loop. (1985) (157)
- Oligomerization and Cooperative RNA Synthesis Activity of Hepatitis C Virus RNA-Dependent RNA Polymerase (2002) (156)
- Poliovirus RNA recombination: mechanistic studies in the absence of selection. (1992) (156)
- Oligomeric structures of poliovirus polymerase are important for function (2001) (151)
- Functional oligomerization of poliovirus RNA-dependent RNA polymerase. (1995) (145)
- Complete Protein Linkage Map of Poliovirus P3 Proteins: Interaction of Polymerase 3Dpol with VPg and with Genetic Variants of 3AB (1998) (138)
- Inhibition of Cellular Autophagy Deranges Dengue Virion Maturation (2012) (135)
- Mapping the topography of DNA wrapped around gyrase by nucleolytic and chemical probing of complexes of unique DNA sequences (1981) (132)
- Genetic dissection of interaction between poliovirus 3D polymerase and viral protein 3AB (1997) (130)
- Trans-dominant inhibition of RNA viral replication can slow growth of drug-resistant viruses (2005) (128)
- DNA topoisomerases. (1981) (122)
- Mapping of single-stranded regions in duplex DNA at the sequence level: single-strand-specific cytosine methylation in RNA polymerase-promoter complexes. (1983) (121)
- Bottleneck-mediated quasispecies restriction during spread of an RNA virus from inoculation site to brain. (2006) (115)
- Nonstructural Protein Precursor NS4A/B from Hepatitis C Virus Alters Function and Ultrastructure of Host Secretory Apparatus (2003) (111)
- Inhibition of cellular protein secretion by picornaviral 3A proteins. (2005) (109)
- Role of Microtubules in Extracellular Release of Poliovirus (2009) (106)
- Modified cyclodextrins as broad-spectrum antivirals (2020) (105)
- Clustered charged-to-alanine mutagenesis of poliovirus RNA-dependent RNA polymerase yields multiple temperature-sensitive mutants defective in RNA synthesis (1994) (101)
- Visualization and Functional Analysis of RNA-Dependent RNA Polymerase Lattices (2002) (99)
- Changes in the DNA structure of the lac UV5 promoter during formation of an open complex with Escherichia coli RNA polymerase. (1985) (98)
- Structure-function analysis of coxsackie B3 virus protein 2B. (1997) (96)
- The polymerase in its labyrinth: mechanisms and implications of RNA recombination (1991) (93)
- Potential subversion of autophagosomal pathway by picornaviruses (2008) (91)
- The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites (2016) (90)
- Mutations in VP1 of poliovirus specifically affect both encapsidation and release of viral RNA (1990) (86)
- Ribavirin Resistance in Hepatitis C Virus Replicon-Containing Cell Lines Conferred by Changes in the Cell Line or Mutations in the Replicon RNA (2005) (85)
- Subversion of the cellular autophagy pathway by viruses. (2009) (75)
- Similar Structural Basis for Membrane Localization and Protein Priming by an RNA-dependent RNA Polymerase* (2002) (71)
- An RNA-Centric Dissection of Host Complexes Controlling Flavivirus Infection (2019) (68)
- Secretory pathway function, but not cytoskeletal integrity, is required in poliovirus infection. (1994) (62)
- Differential and convergent utilization of autophagy components by positive-strand RNA viruses (2019) (61)
- Poliovirus infection blocks ERGIC-to-Golgi trafficking and induces microtubule-dependent disruption of the Golgi complex (2007) (60)
- Topology of Double-Membraned Vesicles and the Opportunity for Non-Lytic Release of Cytoplasm (2005) (58)
- Temperature-sensitive poliovirus mutant fails to cleave VP0 and accumulates provirions (1990) (58)
- Site Size of Cooperative Single-stranded RNA Binding by Poliovirus RNA-dependent RNA Polymerase* (1998) (57)
- Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease (2021) (54)
- Escape of non-enveloped virus from intact cells. (2015) (52)
- Escherichia coli DNA topoisomerase I catalyzed linking of single-stranded rings of complementary base sequences. (1978) (50)
- Enzymatic and nonenzymatic functions of viral RNA-dependent RNA polymerases within oligomeric arrays. (2010) (50)
- RNA binding properties of poliovirus subviral particles (1995) (49)
- Poliovirus RNA recombination in cell-free extracts. (1997) (48)
- Competing pathways control host resistance to virus via tRNA modification and programmed ribosomal frameshifting (2012) (45)
- The cleavage of DNA by type-I DNA topoisomerases. (1984) (39)
- Direct introduction and transient expression of capped and non-capped RNA in Saccharomyces cerevisiae. (1991) (38)
- Dominant drug targets suppress the emergence of antiviral resistance (2014) (34)
- Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 (2016) (33)
- Intramolecular and Intermolecular Uridylylation by Poliovirus RNA-Dependent RNA Polymerase (2006) (33)
- Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652 (2016) (31)
- KH domain integrity is required for wild-type localization of Sam68. (1998) (30)
- Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primer. (2006) (28)
- Suppression of Drug Resistance in Dengue Virus (2015) (27)
- The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy (2018) (26)
- Targeting intramolecular proteinase NS2B/3 cleavages for trans-dominant inhibition of dengue virus (2018) (25)
- Intracellular Topology and Epitope Shielding of Poliovirus 3A Protein (2004) (20)
- Allosteric Effects of Ligands and Mutations on Poliovirus RNA-Dependent RNA Polymerase (2005) (20)
- Exploiting Genetic Interference for Antiviral Therapy (2016) (19)
- Double-membraned Liposomes Sculpted by Poliovirus 3AB Protein* (2013) (19)
- Interstitial contacts in an RNA-dependent RNA polymerase lattice. (2011) (18)
- Cell Biology of Enterovirus Infection (1995) (18)
- Conditional poliovirus mutants made by random deletion mutagenesis of infectious cDNA (1990) (18)
- Genetic analysis of picornaviruses (1992) (17)
- My Cousin, My Enemy: quasispecies suppression of drug resistance (2016) (16)
- Bypass Suppression of Small-Plaque Phenotypes by a Mutation in Poliovirus 2A That Enhances Apoptosis (2009) (15)
- Regulation of a double-stranded RNA modification activity in human cells (1991) (12)
- Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer (2020) (12)
- Poliovirus 3 A Protein Limits Interleukin-6 ( IL-6 ) , IL-8 , and Beta Interferon Secretion during Viral Infection (2001) (11)
- Genome Replication II: the Process (2010) (10)
- Long non-coding RNA gene regulation and trait associations across human tissues (2019) (10)
- Nonlytic spread of naked viruses (2015) (6)
- Complete three-dimensional structures of picornaviral RNA-dependent RNA polymerases. (2004) (6)
- mutagenic nucleotide analogs via increased fidelity A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to (2003) (6)
- Unconventional secretion of hepatitis A virus (2017) (6)
- Detection and Differentiation of Multiple Viral RNAs Using Branched DNA FISH Coupled to Confocal Microscopy and Flow Cytometry (2018) (5)
- Structure-Function Analysis of Coxsackie B 3 Virus Protein 2 B (2017) (5)
- The Ins and Outs of Viral Infection: Keystone Meeting Review (2014) (4)
- Visualization and Functional Analysis of RNA-Dependent (2002) (4)
- Transmission genetics of drug-resistant hepatitis C virus (2018) (4)
- A Targeted Computational Screen of the SWEETLEAD Database Reveals FDA-Approved Compounds with Anti-Dengue Viral Activity (2020) (3)
- Poliovirus RNA recombination. (1991) (3)
- RNA: Transcription, transfection and quantitation (1996) (3)
- The photocatalytic production of organic-free water for molecular biological and pharmaceutical applications. (1994) (3)
- Barley research reviews 1986-91 : session and workshop summaries (1992) (2)
- Barley genetics VI : proceedings of the sixth International Barley Genetics Symposium, July 22-27, 1991, Helsingborg, Sweden (1991) (2)
- The molecular basis of viral replication (1988) (1)
- The Role of Oligomerization in Poliovirus Polymerase Function (2011) (0)
- Intermolecular Contacts Required to Form Planar Lattices of Poliovirus RNA-dependent RNA Polymerase (2008) (0)
- Author response: Dominant drug targets suppress the emergence of antiviral resistance (2014) (0)
- PLOS Pathogens 2017 Reviewer and Editorial Board Thank You (2018) (0)
- Author response: Transmission genetics of drug-resistant hepatitis C virus (2018) (0)
- 331 – The Long Non-Coding Rna, Ifng-As1/Nest, is Associated with IBD and Potentiates a Pro-Inflammatory Signaling Cascade (2019) (0)
- F-105 Roles of autophagy and its components in viral assembly and spread (2014) (0)
- Variant enterovirus A71 found in immune-suppressed patient binds to heparan sulfate and exhibits neurotropism in B-cell-depleted mice. (2023) (0)
- infected cells Human protein Sam 68 relocalization and interaction with poliovirus RNA polymerase in (0)
- P151 THE LONG NON-CODING RNA, IFNG-AS1/NEST, IS ASSOCIATED WITH IBD AND DRIVES A PRO-INFLAMMATORY SIGNALING CASCADE (2019) (0)
- P151 THE LONG NON-CODING RNA, IFNG-AS1/NEST, IS ASSOCIATED WITH IBD AND DRIVES A PRO-INFLAMMATORY SIGNALING CASCADE. (2019) (0)
- Su1055 - Gene Expression Profiling Identifies Ifng-As1/Nest as a Long Non-Coding RNA Associated with IBD (2018) (0)
- Sculpting and Subversion of Membranes during Poliovirus in Assembly of RNA Replication Complexes and in Egress (2013) (0)
- RNA polymerase-promoter complexes (cytosine N-3 methylation/lac promoter/trp promoter/trp-lac (tac) hybrid promoter) (1983) (0)
- Investigating Ph-Induced Changes of the Influenza a Virus Matrix Layer (2018) (0)
- Mechanosensitive extrusion of Enterovirus A71-infected cells from colonic organoids (2023) (0)
- Humanprotein Sam68relocalization andinteraction with poliovirus RNA polymerase ininfected cells (1996) (0)
- Escherichia coli DNAtopoisomerase Icatalyzed linldng ofsingle-stranded rings ofcomplementary base sequences (1978) (0)
- Treatment Of Dengue Virus Infection With Repurposed Pharmaceuticals that Inhibit Autophagy (2018) (0)
- Enteroviruses Future: Omics, Molecular Biology and Control (2018) (0)
- Surface for catalysis by poliovirus RNA dependent RNA polymerase (2012) (0)
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