Kate Schroder
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Computer Science
Kate Schroder's Degrees
- PhD Computer Science Stanford University
- Masters Computer Science University of California, Berkeley
- Bachelors Computer Science University of California, Berkeley
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(Suggest an Edit or Addition)Kate Schroder's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Inflammasomes (2010) (3869)
- Interferon‐γ: an overview of signals, mechanisms and functions (2004) (3376)
- Interferon-gamma: an overview of signals, mechanisms and functions. (2004) (1891)
- A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases (2015) (1657)
- NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? (2010) (1529)
- The NLRP3 Inflammasome: A Sensor for Metabolic Danger? (2010) (997)
- The regulated retrotransposon transcriptome of mammalian cells (2009) (735)
- NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice. (2017) (587)
- Osteal Tissue Macrophages Are Intercalated throughout Human and Mouse Bone Lining Tissues and Regulate Osteoblast Function In Vitro and In Vivo1 (2008) (585)
- The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line (2009) (441)
- MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition (2019) (423)
- Expression analysis of G Protein-Coupled Receptors in mouse macrophages (2008) (415)
- Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice (2018) (411)
- The Macrophage-Inducible C-Type Lectin, Mincle, Is an Essential Component of the Innate Immune Response to Candida albicans1 (2008) (398)
- AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC (2013) (386)
- Tiny RNAs associated with transcription start sites in animals (2009) (370)
- Differential Expression of NLRP3 among Hematopoietic Cells (2011) (307)
- Signal integration between IFNgamma and TLR signalling pathways in macrophages. (2006) (307)
- Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity (2018) (306)
- Noncanonical inflammasome signaling elicits gasdermin D–dependent neutrophil extracellular traps (2018) (303)
- The neutrophil NLRC4 inflammasome selectively promotes IL-1β maturation without pyroptosis during acute Salmonella challenge. (2014) (302)
- K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria. (2016) (292)
- Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner (2017) (285)
- DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF‐κB (2009) (284)
- Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages (2012) (278)
- Activity of Recombinant Dengue 2 Virus NS3 Protease in the Presence of a Truncated NS2B Co-factor, Small Peptide Substrates, and Inhibitors* (2001) (277)
- NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase‐4 and caspase‐5 (2015) (236)
- Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation (2016) (236)
- LPS regulates proinflammatory gene expression in macrophages by altering histone deacetylase expression (2006) (227)
- Differential effects of selective HDAC inhibitors on macrophage inflammatory responses to the Toll‐like receptor 4 agonist LPS (2010) (186)
- Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion. (2018) (179)
- MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice (2018) (177)
- Histone deacetylase inhibitors decrease Toll‐like receptor‐mediated activation of proinflammatory gene expression by impairing transcription factor recruitment (2007) (175)
- Pattern recognition receptor function in neutrophils. (2013) (171)
- Probing the S100 protein family through genomic and functional analysis. (2004) (160)
- Inflammasome signaling and regulation of interleukin-1 family cytokines (2019) (160)
- TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity (2015) (156)
- The mammalian PYHIN gene family: Phylogeny, evolution and expression (2012) (150)
- Innate Immunity: Cytoplasmic DNA Sensing by the AIM2 Inflammasome (2009) (147)
- Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction. (2012) (142)
- G‐protein‐coupled receptor expression, function, and signaling in macrophages (2007) (121)
- NLRC5 Deficiency Selectively Impairs MHC Class I- Dependent Lymphocyte Killing by Cytotoxic T Cells (2012) (121)
- Mechanisms of unconventional secretion of IL-1 family cytokines. (2015) (117)
- Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling (2014) (111)
- A rescue strategy for multimapping short sequence tags refines surveys of transcriptional activity by CAGE. (2008) (104)
- XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation. (2017) (102)
- The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins (2020) (96)
- Data-driven normalization strategies for high-throughput quantitative RT-PCR (2009) (96)
- Neutrophil-Derived S100A8/A9 Amplify Granulopoiesis After Myocardial Infarction (2020) (93)
- Macrophage Activation and Differentiation Signals Regulate Schlafen-4 Gene Expression: Evidence for Schlafen-4 as a Modulator of Myelopoiesis (2011) (87)
- TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity. (2015) (86)
- Alternate transcription of the Toll-like receptor signaling cascade (2006) (82)
- Colony‐stimulating factor‐1 (CSF‐1) delivers a proatherogenic signal to human macrophages (2009) (80)
- Histone Deacetylase 7 Promotes Toll-like Receptor 4-dependent Proinflammatory Gene Expression in Macrophages* (2013) (80)
- A Novel Flow Cytometric Method To Assess Inflammasome Formation (2015) (75)
- The Inflammasome Adaptor ASC Induces Procaspase-8 Death Effector Domain Filaments* (2015) (69)
- Salmonella employs multiple mechanisms to subvert the TLR‐inducible zinc‐mediated antimicrobial response of human macrophages (2016) (69)
- Phosphoinositide 3-kinase δ regulates membrane fission of Golgi carriers for selective cytokine secretion (2010) (66)
- Strain- and host species-specific inflammasome activation, IL-1β release, and cell death in macrophages infected with uropathogenic Escherichia coli (2015) (63)
- Update of the FANTOM web resource: from mammalian transcriptional landscape to its dynamic regulation (2010) (61)
- Neutrophil Extracellular Traps in Host Defense. (2019) (60)
- LPS regulates a set of genes in primary murine macrophages by antagonising CSF-1 action. (2005) (59)
- An antioxidant role for catecholate siderophores in Salmonella. (2013) (58)
- The NLRP3 inflammasome triggers sterile neuroinflammation and Alzheimer's disease. (2020) (54)
- Endothelial cells are not productively infected by SARS‐CoV‐2 (2021) (53)
- PU.1 and ICSBP control constitutive and IFN‐γ‐regulated Tlr9 gene expression in mouse macrophages (2007) (52)
- NLRP3 and pyroptosis blockers for treating inflammatory diseases. (2022) (49)
- Questions and controversies in innate immune research: what is the physiological role of NLRP3? (2016) (43)
- Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals (2016) (42)
- Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling (2015) (40)
- Differential Effects of CpG DNA on IFN-β Induction and STAT1 Activation in Murine Macrophages versus Dendritic Cells: Alternatively Activated STAT1 Negatively Regulates TLR Signaling in Macrophages1 (2007) (38)
- Antimicrobial functions of inflammasomes. (2013) (37)
- Dimerization and auto-processing induce caspase-11 protease activation within the non-canonical inflammasome (2018) (37)
- Sulfonylureas as Concomitant Insulin Secretagogues and NLRP3 Inflammasome Inhibitors (2017) (36)
- The combination of gene perturbation assay and ChIP-chip reveals functional direct target genes for IRF8 in THP-1 cells. (2010) (33)
- Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice (2015) (32)
- Hepatic expression profiling identifies steatosis-independent and steatosis-driven advanced fibrosis genes. (2018) (31)
- Sphingomyelin Phosphodiesterase Acid-like 3A (SMPDL3A) Is a Novel Nucleotide Phosphodiesterase Regulated by Cholesterol in Human Macrophages* (2014) (31)
- Development of a DNA barcode tagging method for monitoring dynamic changes in gene expression by using an ultra high-throughput sequencer. (2008) (30)
- The Salmonella pathogenicity island‐2 subverts human NLRP3 and NLRC4 inflammasome responses (2018) (29)
- NLRP12 is a neutrophil-specific, negative regulator of in vitro cell migration but does not modulate LPS- or infection-induced NF-κB or ERK signalling. (2016) (29)
- The rOX‐stars of inflammation: links between the inflammasome and mitochondrial meltdown (2020) (28)
- Lipopolysaccharide promotes Drp1‐dependent mitochondrial fission and associated inflammatory responses in macrophages (2020) (27)
- Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion (2018) (27)
- IFN Regulatory Factor 3 Balances Th1 and T Follicular Helper Immunity during Nonlethal Blood-Stage Plasmodium Infection (2018) (25)
- Assessment of Inflammasome Formation by Flow Cytometry (2016) (23)
- The murine neutrophil NLRP3 inflammasome is activated by soluble but not particulate or crystalline agonists (2016) (23)
- The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders (2021) (22)
- Salmonella-induced inflammasome activation in humans. (2017) (22)
- The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade (2011) (22)
- Role of the NLRP3 inflammasome in a model of acute burn-induced pain. (2017) (21)
- Inflammatory Caspases: Toward a Unified Model for Caspase Activation by Inflammasomes. (2022) (20)
- Studies on the binding of copper to dopamine beta-monooxygenase and other proteins using the Cu2+ ion-selective electrode. (1986) (20)
- Tiered DNA sensors for escalating responses (2019) (20)
- Mitochondrial DNA synthesis fuels NLRP3 inflammasome (2018) (18)
- IL-1 Contributes to the Anti-Cancer Efficacy of Ingenol Mebutate (2016) (16)
- Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release (2021) (15)
- Inhibitors of class I histone deacetylases attenuate thioacetamide‐induced liver fibrosis in mice by suppressing hepatic type 2 inflammation (2019) (15)
- Variation in hemolysin A expression between uropathogenic Escherichia coli isolates determines NLRP3‐dependent vs. ‐independent macrophage cell death and host colonization (2019) (14)
- A small molecule inhibitior of the NLRP 3 inflammasome is a potential therapeutic for inflammatory diseases (2015) (13)
- Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis (2018) (13)
- In life there is death: How epithelial tissue barriers are preserved despite the challenge of apoptosis (2017) (13)
- The structure of the caspase recruitment domain of BinCARD reveals that all three cysteines can be oxidized. (2013) (12)
- Lack of protein prenylation promotes NLRP3 inflammasome assembly in human monocytes. (2019) (12)
- Endothelial cells elicit a pro-inflammatory response to SARS-CoV-2 without productive viral infection (2021) (9)
- The E3 ubiquitin ligase RNF144B is LPS‐inducible in human, but not mouse, macrophages and promotes inducible IL‐1β expression (2016) (9)
- Differential effects of CpG DNA on IFN-beta induction and STAT1 activation in murine macrophages versus dendritic cells (2016) (8)
- Burn the house, save the day: pyroptosisin pathogen restriction (2016) (8)
- Interleukin-1 is overexpressed in injured muscles following spinal cord injury and promotes neurogenic heterotopic ossification (2021) (8)
- TRAF6 is a nexus for TLR‐STAT1 crosstalk (2014) (8)
- Quantifying Caspase-1 Activity in Murine Macrophages. (2018) (7)
- Design, synthesis and evaluation of an NLRP3 inhibitor diazirine photoaffinity probe (2020) (7)
- Mechanisms and Consequences of Inflammasome Activation. (2018) (7)
- Inflammasome activation and IL‐1β signalling in group A Streptococcus disease (2021) (5)
- Streptolysins are the primary inflammasome activators in macrophages during Streptococcus pyogenes infection (2021) (5)
- Novel insights into the innate immune response to non‐tuberculous Mycobacteria (2012) (5)
- gene expression in mouse macrophages (2007) (5)
- Placental inflammasome signaling: Protection for mother and baby (2020) (4)
- Parkinson's disease: connecting mitochondria to inflammasomes. (2022) (4)
- Sulfonylureas and related compounds and use of the same (2016) (4)
- SCIMP is a spatiotemporal transmembrane scaffold for Erk1/2 to direct pro-inflammatory signaling in TLR-activated macrophages. (2021) (3)
- Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations (2018) (3)
- Inflammasomes and the IL-1 Family in Bone Homeostasis and Disease (2022) (3)
- Innate immunity, the constant gardener of antimicrobial defense. (2013) (2)
- Aim2 suppresses cigarette smoke‐induced neutrophil recruitment, neutrophil caspase‐1 activation and anti‐Ly6G‐mediated neutrophil depletion (2022) (2)
- Liver repercussions of defective gut surveillance (2012) (2)
- Caspase-4 dimerisation and D289 auto-processing elicits an interleukin-1β converting enzyme (2023) (2)
- Corrigendum: Tiny RNAs associated with transcription start sites in animals (2009) (2)
- Correction to Supporting Information for Conos et al., Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner (2017) (2)
- Macrophages only sense infectious SARS-CoV-2 when they express sufficient ACE2 to permit viral entry, where rapid cytokine responses then limit viral replication (2023) (1)
- Caging NLRP3 tames inflammasome activity (2021) (1)
- Zebrafish earns its stripes for in vivo ASC speck dynamics (2017) (1)
- A novel approach to investigate the assembly of the NOD‐like receptor inflammasomes (152.7) (2014) (1)
- Crosstalk between STATs and TLRs TRAF 6 is a nexus for TLR-STAT 1 crosstalk (2014) (1)
- Come on mtDNA, light my fire. (2022) (1)
- NLRC3 Restrains Responses to a T. (2018) (1)
- Inflammasomes and inflammation (2014) (1)
- The mammalian PYHIN gene family: Phylogeny, evolution and expression (2012) (1)
- Author Correction: Mitochondrial DNA synthesis fuels NLRP3 inflammasome (2018) (1)
- Cellular Immunity And Pathological Alterations In Ms Grey Matter (2009) (1)
- Mitochondrial DNA synthesis fuels NLRP3 inflammasome (2018) (0)
- 210: Exploring NLRP12 – An emerging member of NOD-like receptor family (2014) (0)
- Rapid lamellipodial responses by neighbor cells drive epithelial sealing in response to pyroptotic cell death. (2022) (0)
- The Impact of CAGE Data on Understanding Macrophage Transcriptional Biology (2019) (0)
- Regulation and function of toll-like receptor 9 in macrophages (2005) (0)
- Paraquat activates the NLRP3 Inflammasome in microglia via the NADPH oxidase pathway (2016) (0)
- Author Correction: Mitochondrial DNA synthesis fuels NLRP3 inflammasome (2018) (0)
- Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analyses (2022) (0)
- PU.1 and ICSBP regulate the tlr9 promoter in mouse macrophages (2005) (0)
- Apical extrusion prevents apoptosis from activating an acute inflammatory program in epithelia (2023) (0)
- Histone Deacetylase Inhibitors Attenuate Hepatic Fibrosis through Suppression of Group 2 Innate Lymphoid Cells and Type 2 Inflammation (2019) (0)
- XIAP deficiency results in excess NLRP3 inflammasome activation and cell death as a consequence of TLR-MyD88 induced cIAP1-TRAF2 degradation (2017) (0)
- Autophagy, Inflammation, and Metabolism (AIM) Center in its second year (2019) (0)
- Apoptotic cell death in disease—Current understanding of the NCCD 2023 (2023) (0)
- Mitochondrial dynamics in macrophages: divide to conquer or unite to survive? (2023) (0)
- Interleukin-1 b Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and-Independent Secretion Graphical (2018) (0)
- Primary murine osteoblast cultures contain macrophages that enhance osteoblast mineralisation (2007) (0)
- Innate Immunity in the Sunshine State (2012) (0)
- Stoking inflammasome fires in the COVID-19 neighborhood (2023) (0)
- Innate Immune Response to Mincle, Is an Essential Component of the The Macrophage-Inducible C-Type Lectin, (2012) (0)
- Macrophage ACE2 is necessary for SARS-CoV-2 replication and subsequent cytokine responses that restrict continued virion release (2023) (0)
- NLRC5 deficiency impairs MHC class I-dependent lymphocyte killing by cytotoxic T cells (2012) (0)
- Expression and function of Schlafen-4 in macrophage biology and inflammation (2008) (0)
- Inflammasome Formation A Novel Flow Cytometric Method To Assess (2014) (0)
- The adaptor protein ASC controls transplantation outcomes independently of the inflammasome (TRAN1P.951) (2015) (0)
- Inflammatory response sculpting by neutrophil inflammasomes (2016) (0)
- Functional significance of evolutionary divergence in Toll-like receptor-regulated gene expression in human versus mouse (2012) (0)
- 1020 - NEW INSIGHTS INTO INFLAMMASOME SIGNALLING AND FUNCTION DURING INFLAMMATION (2019) (0)
- RNA-sequencing analysis of biopsies from chronic liver disease patients identifies gene signatures associated with progressive liver disease (2018) (0)
- This information is current as Regulates TLR Signaling in Macrophages Alternatively Activated STAT1 Negatively Macrophages versus Dendritic Cells: Induction and STAT1 Activation in Murine β Differential Effects of CpG DNA on IFN- (2017) (0)
- Explorer Osteal tissue macrophages are intercalated throughout human and mouse bone lining tissues and regulate osteoblast function in vitro and in vivo (2018) (0)
- MCC950 is a potent and specific inhibitor of the NLRP3 inflammasome and a novel potential therapeutic for NLRP3 driven diseases (2014) (0)
- HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. (2023) (0)
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What Schools Are Affiliated With Kate Schroder?
Kate Schroder is affiliated with the following schools:
