Katherine Franz
#94,908
Most Influential Person Now
American chemist
Katherine Franz's AcademicInfluence.com Rankings
Katherine Franzchemistry Degrees
Chemistry
#2506
World Rank
#3425
Historical Rank
Organic Chemistry
#926
World Rank
#1039
Historical Rank
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Chemistry
Katherine Franz's Degrees
- Bachelors Chemistry University of California, Berkeley
Why Is Katherine Franz Influential?
(Suggest an Edit or Addition)According to Wikipedia, Katherine J. Franz is the chair of the department of chemistry at Duke University. She studies metal ion coordination in biological systems and looks to use the insight to manage species such as copper and iron. Franz was awarded the American Chemical Society Award for Encouraging Women into Careers in the Chemical Sciences.
Katherine Franz's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Application of metal coordination chemistry to explore and manipulate cell biology. (2009) (695)
- Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols. (2012) (268)
- Coordination chemistry of copper proteins: how nature handles a toxic cargo for essential function. (2012) (259)
- Connecting copper and cancer: from transition metal signalling to metalloplasia (2021) (225)
- Protein alignment by a coexpressed lanthanide-binding tag for the measurement of residual dipolar couplings. (2003) (167)
- Structural origin of the high affinity of a chemically evolved lanthanide-binding peptide. (2004) (148)
- A Powerful Combinatorial Screen to Identify High‐Affinity Terbium(III)‐Binding Peptides (2003) (139)
- Lanthanide‐Binding Tags as Versatile Protein Coexpression Probes (2003) (136)
- A pro-chelator triggered by hydrogen peroxide inhibits iron-promoted hydroxyl radical formation. (2006) (131)
- Minding metals: tailoring multifunctional chelating agents for neurodegenerative disease. (2010) (128)
- Copper signaling axis as a target for prostate cancer therapeutics. (2014) (123)
- Model peptides provide new insights into the role of histidine residues as potential ligands in human cellular copper acquisition via Ctr1. (2011) (123)
- A Mets motif peptide found in copper transport proteins selectively binds Cu(I) with methionine-only coordination. (2005) (119)
- Fe(III)-coordination properties of neuromelanin components: 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid. (2006) (118)
- Methionine motifs of copper transport proteins provide general and flexible thioether-only binding sites for Cu(I) and Ag(I) (2010) (78)
- A Prochelator Activated by Hydrogen Peroxide Prevents Metal‐Induced Amyloid β Aggregation (2009) (77)
- A prochelator activated by beta-secretase inhibits Abeta aggregation and suppresses copper-induced reactive oxygen species formation. (2010) (75)
- A comparison of methionine, histidine and cysteine in copper(I)-binding peptides reveals differences relevant to copper uptake by organisms in diverse environments. (2011) (73)
- Exploiting innate immune cell activation of a copper-dependent antimicrobial agent during infection. (2014) (73)
- NO Disproportionation Reactivity of Fe Tropocoronand Complexes (1999) (71)
- Introduction: Metals in Medicine. (2019) (69)
- Pharmacological activity of metal binding agents that alter copper bioavailability. (2015) (66)
- Coordination of platinum therapeutic agents to met-rich motifs of human copper transport protein1. (2010) (62)
- Aminotroponiminates as ligands for potential metal-based nitric oxide sensors. (2000) (62)
- Disproportionation of Nitric Oxide Promoted by a Mn Tropocoronand (1998) (60)
- Phosphorylation of an α-Synuclein Peptide Fragment Enhances Metal Binding (2005) (57)
- Keys for unlocking photolabile metal-containing cages. (2011) (57)
- A photolabile ligand for light-activated release of caged copper. (2008) (52)
- Phosphorylation-dependent metal binding by α-synuclein peptide fragments (2007) (50)
- A Photo-Caged Platinum(II) Complex That Increases Cytotoxicity upon Light Activation (2010) (49)
- Toward the detection of cellular copper(II) by a light-activated fluorescence increase. (2010) (46)
- Emerging Opportunities To Manipulate Metal Trafficking for Therapeutic Benefit. (2019) (46)
- Modifications of boronic ester pro-chelators triggered by hydrogen peroxide tune reactivity to inhibit metal-promoted oxidative stress. (2007) (46)
- Iron prochelator BSIH protects retinal pigment epithelial cells against cell death induced by hydrogen peroxide. (2008) (45)
- Model Peptide Studies Reveal a Mixed Histidine-Methionine Cu(I) Binding Site at the N-Terminus of Human Copper Transporter 1. (2015) (44)
- Clawing back: broadening the notion of metal chelators in medicine. (2013) (43)
- Specific Histidine Residues Confer Histatin Peptides with Copper-Dependent Activity against Candida albicans. (2017) (39)
- Prochelator BHAPI protects cells against paraquat-induced damage by ROS-triggered iron chelation. (2012) (38)
- Leveraging γ-Glutamyl Transferase To Direct Cytotoxicity of Copper Dithiocarbamates against Prostate Cancer Cells. (2018) (38)
- A Lytic Polysaccharide Monooxygenase-like protein functions in fungal copper import and meningitis (2019) (37)
- Pentacoordinate cobalt(III) thiolate and nitrosyl tropocoronand compounds. (2001) (36)
- Toward the development of prochelators as fluorescent probes of copper-mediated oxidative stress. (2010) (31)
- Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria. (2018) (31)
- Polymer pendant ligand chemistry-5. The selective and competitive removal of Ag+, Hg2+, Cu2+, Pb2+ and Cd2+ ions from aqueous solution utilizing a n-sulfonylethylenebis(dithiocarbamate) ligand anchored on macroporous polystyrene-divinylbenzene beads (1996) (29)
- Comparison of various iron chelators and prochelators as protective agents against cardiomyocyte oxidative injury. (2014) (27)
- Monitoring β-secretase activity in living cells with a membrane-anchored FRET probe. (2012) (27)
- Prochelators triggered by hydrogen peroxide provide hexadentate iron coordination to impede oxidative stress. (2011) (26)
- Characterization of a photoswitching chelator with light-modulated geometric, electronic, and metal-binding properties. (2014) (24)
- Stimulus-Responsive Prochelators for Manipulating Cellular Metals. (2016) (24)
- Chemical and functional properties of metal chelators that mobilize copper to elicit fungal killing of Cryptococcus neoformans. (2017) (23)
- Nitrosyl transfer from manganese to iron in tropocoronand complexes. (2000) (21)
- Light uncages a copper complex to induce nonapoptotic cell death. (2013) (20)
- Polymer Pendant Ligand Chemistry. 3. A Biomimetic Approach to Selective Metal Ion Removal and Recovery from Aqueous Solution with Polymer-Supported Sulfonated Catechol and Linear Catechol Amide Ligands (1995) (19)
- Development of next-generation photolabile copper cages with improved copper binding properties. (2010) (17)
- Synthetic and structural studies of linear bis-catechol amide, N,N{prime}-bis(2,3-dihydroxybenzoyl)-1,7-diazaheptane (5-LICAM), and its complexes with Ni{sup 2+} and Co{sup 2+}: Utilization of a polymer-supported, sulfonated analog, 5-LICAMS, as a biomimetic ligand for divalent metal ion removal fro (1995) (17)
- Copper shares a piece of the pi. (2008) (17)
- A prochelator with a modular masking group featuring hydrogen peroxide activation with concurrent fluorescent reporting. (2014) (17)
- Application of inorganic chemistry for non-cancer therapeutics. (2012) (16)
- A boronate prochelator built on a triazole framework for peroxide-triggered tridentate metal binding. (2012) (15)
- Phosphorylation-dependent metal binding by alpha-synuclein peptide fragments. (2007) (14)
- Novel aminoalkyl tris-cyclometalated iridium complexes as cellular stains. (2016) (14)
- Counterions influence reactivity of metal ions with cysteinyldopa model compounds. (2008) (13)
- Introduction to "cellular metal homeostasis and trafficking". (2009) (13)
- Protein Folding Stability Changes Across the Proteome Reveal Targets of Cu Toxicity in E. coli. (2020) (12)
- Cardioprotective effects of iron chelator HAPI and ROS-activated boronate prochelator BHAPI against catecholamine-induced oxidative cellular injury. (2016) (12)
- Supramolecular Alcohol–Amine Crystals and Their Hydrogen‐Bond Patterns (1998) (12)
- NO‐Erkennung durch einen Metallkomplex als Folge der selektiven Dissoziation eines Liganden (2000) (11)
- Characterization of cytoprotective and toxic properties of iron chelator SIH, prochelator BSIH and their degradation products. (2016) (11)
- Synthesis and characterization of copper(II) complexes of cysteinyldopa and benzothiazine model ligands related to pheomelanin. (2006) (11)
- LC-UV/MS methods for the analysis of prochelator-boronyl salicylaldehyde isonicotinoyl hydrazone (BSIH) and its active chelator salicylaldehyde isonicotinoyl hydrazone (SIH). (2015) (11)
- Single-Molecule Activation and Quantification of Mechanically Triggered Palladium-Carbene Bond Dissociation. (2021) (11)
- Phosphorylation of an alpha-synuclein peptide fragment enhances metal binding. (2005) (10)
- F1000Prime recommendation of Copper stress in Staphylococcus aureus leads to adaptive changes in central carbon metabolism. (2019) (10)
- Dithiocarbamate prodrugs activated by prostate specific antigen to target prostate cancer. (2020) (9)
- Candida albicans reprioritizes metal handling during fluconazole stress. (2019) (9)
- A Cell-Permeable Fluorescent Prochelator Responds to Hydrogen Peroxide and Metal Ions by Decreasing Fluorescence. (2012) (9)
- A Cephalosporin Prochelator Inhibits New Delhi Metallo-β-Lactamase 1 without Removing Zinc. (2020) (9)
- A multifunctional, light-activated prochelator inhibits UVA-induced oxidative stress. (2015) (9)
- Copper potentiates azole antifungal activity in a way that does not involve complex formation. (2019) (9)
- Metal-binding hydrazone photoswitches for visible light reactivity and variable relaxation kinetics. (2017) (7)
- Fluconazole analogues with metal-binding motifs impact metal-dependent processes and demonstrate antifungal activity in Candida albicans (2020) (7)
- Schlüssel zum Öffnen photolabiler, metallhaltiger Käfige (2011) (7)
- Electronic structure of a paramagnetic {MNO}6 complex: MnNO 5,5-tropocoronand. (2010) (7)
- A comparison of methionine, histidine and cysteine in copper(I)-binding peptides reveals differences relevant to copper uptake by organisms in diverse environments. (2011) (7)
- Benzimidazole and Benzoxazole Zinc Chelators as Inhibitors of Metallo‐β‐Lactamase NDM‐1 (2020) (6)
- Detection of Metal Ions, Anions and Small Molecules Using Metal Complexes (2014) (6)
- Leveraging γ‐Glutamyl Transferase To Direct Cytotoxicity of Copper Dithiocarbamates against Prostate Cancer Cells (2018) (5)
- Intestinal mucin is a chaperone of multivalent copper (2022) (5)
- NO Disproportionation Reactivity of Fe Tropocoronand Complexes J. Am. Chem. Soc. 1999, 121, 10504−10512. (2001) (5)
- Prospective clinical trial of disulfiram plus copper in men with metastatic castration‐resistant prostate cancer (2022) (5)
- A prochelator peptide designed to use heterometallic cooperativity to enhance metal ion affinity† †Electronic supplementary information (ESI) available: Experimental procedures and Fig. S1–S9 showing plots of lifetime, absorbance, titration, HPLC and mass spectra. See DOI: 10.1039/c5sc00602c (2015) (4)
- The hydrolytic susceptibility of prochelator BSIH in aqueous solutions. (2017) (4)
- Membrane Transporters Involved in the Antimicrobial Activities of Pyrithione in Escherichia coli (2021) (3)
- Zinc binding inhibits cellular uptake and antifungal activity of Histatin-5 in Candida albicans (2022) (3)
- Copper Availability Influences the Transcriptomic Response of Candida albicans to Fluconazole Stress (2021) (2)
- Modifying aroylhydrazone prochelators for hydrolytic stability and improved cytoprotection against oxidative stress. (2018) (2)
- Development of lanthanide-binding peptides as natively expressed protein probes (2003) (2)
- 3.09 – Bioinorganic Neurochemistry (2013) (1)
- The highways and byways of bioinorganic chemistry. (2010) (1)
- Grab ‘n Go: Siderophore-Binding Proteins Provide Pathogens a Quick Fix to Satisfy Their Hunger for Iron (2020) (1)
- Copper In fl uences the Antibacterial Outcomes of a β ‐ Lactamase-Activated Prochelator against Drug-Resistant Bacteria (2018) (1)
- Examination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine (2022) (1)
- Leveraging gamma-glutamyl transferase to direct cytotoxicity of copper dithiocarbamates against prostate cancer cells (2019) (1)
- Preface. Biometals 2014--Proceedings of the 9th International Symposium Biometals 2014 at Duke University, Durham, NC, USA. (2015) (0)
- Connecting copper and cancer: from transition metal signalling to metalloplasia (2021) (0)
- Analysis of Copper-Induced Protein Precipitation across the E. coli Proteome. (2022) (0)
- CCDC 106509: Experimental Crystal Structure Determination (1999) (0)
- Metallomics: Emerging Investigators 2019. (2019) (0)
- Role of Intralysosomal Redox-Active Iron in Oxidative Stress-Induced Damage in Trabecular Meshwork Cells (2008) (0)
- Faculty Opinions recommendation of Intracellular Metal Speciation in Streptococcus sanguinis Establishes SsaACB as Critical for Redox Maintenance. (2020) (0)
- Project Title : Mapping Mechanically Activated Pathways of Metal Coordination Complexes c (2018) (0)
- Note from the President (2019) (0)
- Crystal Structure of a High Affinity Lanthanide-Binding Peptide (LBT) (2004) (0)
- Electronic Structure of a Paramagnetic {MNO}[superscript 6] Complex: MnNO 5,5-Tropocoronand (2010) (0)
- Faculty Opinions recommendation of Bacterial sensors define intracellular free energies for correct enzyme metalation. (2019) (0)
- Keys for Unlocking Photolabile Metal‐Containing Cages. (2011) (0)
- Preface (2015) (0)
- Nitric oxide reactivity of manganese, iron and cobalt tropocoronands and development of fluorescent aminotroponiminates for nitric oxide sensing (2000) (0)
- Dual Antioxidant Activity of Boronate-Based Prochelators: Scavenging Peroxynitrite and Metal Ion Chelation (2011) (0)
- Multiple Modes of Zinc Binding to Histatin 5 Revealed by Buffer-Independent Thermodynamics. (2023) (0)
- Faculty Opinions recommendation of Targeting Mobilization of Ferrous Iron in Pseudomonas aeruginosa Infection with an Iron(II)-Caged LpxC Inhibitor. (2019) (0)
- Cover Picture: A Powerful Combinatorial Screen to Identify High-Affinity Terbium(III)-Binding Peptides (ChemBioChem 4/2003) (2003) (0)
- Faculty Opinions recommendation of Tools and techniques for illuminating the cell biology of zinc. (2020) (0)
- Correction to Copper Influences the Antibacterial Outcomes of a β-Lactamase-Activated Prochelator against Drug-Resistant Bacteria. (2020) (0)
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