Kathrin Muegge
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German physician and molecular biologist
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Kathrin Mueggephilosophy Degrees
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#16259
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Kathrin Mueggebiology Degrees
Biology
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Genetics
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#1932
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#2675
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#2716
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Why Is Kathrin Muegge Influential?
(Suggest an Edit or Addition)According to Wikipedia, Kathrin Muegge is a German physician and molecular biologist researching chromatin organization during embryonic development and in tumor progression. She is a senior investigator and head of the epigenetics section at the Frederick National Laboratory for Cancer Research.
Kathrin Muegge's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Lsh, a member of the SNF2 family, is required for genome-wide methylation. (2001) (395)
- Withdrawal of IL-7 induces Bax translocation from cytosol to mitochondria through a rise in intracellular pH. (1999) (272)
- A G3BP1-Interacting lncRNA Promotes Ferroptosis and Apoptosis in Cancer via Nuclear Sequestration of p53. (2018) (259)
- Interleukin-7: physiological roles and mechanisms of action. (1999) (258)
- Interleukin-1 costimulatory activity on the interleukin-2 promoter via AP-1. (1989) (227)
- Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor beta gene. (1993) (225)
- Advanced Applications of RNA Sequencing and Challenges (2015) (216)
- The trophic action of IL-7 on pro-T cells: inhibition of apoptosis of pro-T1, -T2, and -T3 cells correlates with Bcl-2 and Bax levels and is independent of Fas and p53 pathways. (1998) (196)
- Lsh is involved in de novo methylation of DNA (2006) (180)
- DNA methylation in early development (2010) (174)
- Trophic Factor Withdrawal: p38 Mitogen-Activated Protein Kinase Activates NHE1, Which Induces Intracellular Alkalinization (2001) (169)
- Lsh, an epigenetic guardian of repetitive elements. (2004) (151)
- Interleukin 7 Receptor Control of T Cell Receptor γ Gene Rearrangement: Role of Receptor-associated Chains and Locus Accessibility (1998) (137)
- Lsh is required for meiotic chromosome synapsis and retrotransposon silencing in female germ cells (2006) (129)
- IL-7 receptor and VDJ recombination: trophic versus mechanistic actions. (1997) (112)
- The Interleukin 7 Receptor Is Required for T Cell Receptor γ Locus Accessibility to the V(D)j Recombinase (2000) (112)
- Lsh, a modulator of CpG methylation, is crucial for normal histone methylation (2003) (104)
- Lsh, an SNF2/helicase family member, is required for proliferation of mature T lymphocytes. (2000) (97)
- Bax deficiency partially corrects interleukin-7 receptor α deficiency (2002) (94)
- Lsh, a SNF2 family member, is required for normal murine development. (2001) (93)
- Interleukin-3 Withdrawal Induces an Early Increase in Mitochondrial Membrane Potential Unrelated to the Bcl-2 Family (2001) (91)
- Lsh, chromatin remodeling family member, modulates genome-wide cytosine methylation patterns at nonrepeat sequences (2011) (89)
- Chromatin Remodeling Factor LSH Drives Cancer Progression by Suppressing the Activity of Fumarate Hydratase. (2016) (87)
- Lsh controls Hox gene silencing during development (2007) (86)
- Effect of high fat diet on paternal sperm histone distribution and male offspring liver gene expression (2015) (85)
- Genome-wide DNA methylation patterns in LSH mutant reveals de-repression of repeat elements and redundant epigenetic silencing pathways (2014) (84)
- Lsh controls silencing of the imprinted Cdkn1c gene (2005) (83)
- Cytokines and transcription factors. (1990) (80)
- Association of Lsh, a Regulator of DNA Methylation, with Pericentromeric Heterochromatin Is Dependent on Intact Heterochromatin (2003) (80)
- The SNF2‐like helicase HELLS mediates E2F3‐dependent transcription and cellular transformation (2012) (74)
- Interleukin 1 induction of the c-jun promoter. (1993) (72)
- Defective T-cell receptor γ gene rearrangement in interleukin-7 receptor knockout mice (1997) (70)
- The ATP binding site of the chromatin remodeling homolog Lsh is required for nucleosome density and de novo DNA methylation at repeat sequences (2015) (67)
- Characterization of gene expression, genomic structure, and chromosomal localization of Hells (Lsh). (1998) (66)
- Lsh Participates in DNA Methylation and Silencing of Stem Cell Genes (2009) (65)
- Lsh, a guardian of heterochromatin at repeat elements. (2005) (64)
- Lsh-deficient murine embryonal fibroblasts show reduced proliferation with signs of abnormal mitosis. (2003) (62)
- Bax deficiency partially corrects interleukin-7 receptor alpha deficiency. (2002) (61)
- A novel putative helicase produced in early murine lymphocytes. (1996) (61)
- Duo-Plasmaline — a linearly extended homogeneous low pressure plasma source (1997) (60)
- Defining the Minimal Domain of Ku80 for Interaction with Ku70* (1997) (51)
- Interleukin 1 induces beta-endorphin secretion via Fos and Jun in AtT-20 pituitary cells. (1990) (50)
- Lsh Mediated RNA Polymerase II Stalling at HoxC6 and HoxC8 Involves DNA Methylation (2010) (49)
- Repression of Hox genes by LMP1 in nasopharyngeal carcinoma and modulation of glycolytic pathway genes by HoxC8 (2015) (48)
- IL-7 activates alpha4beta1 integrin in murine thymocytes. (1997) (47)
- Interleukin (IL)-7 Induces Rapid Activation of Pyk2, Which Is Bound to Janus Kinase 1 and IL-7Rα* (2000) (46)
- CG hypomethylation in Lsh−/− mouse embryonic fibroblasts is associated with de novo H3K4me1 formation and altered cellular plasticity (2014) (44)
- Direct evidence for an intracellular role for IFN-gamma. Microinjection of human IFN-gamma induces Ia expression on murine macrophages. (1990) (44)
- DNA hypomethylation caused by Lsh deletion promotes erythroleukemia development (2008) (42)
- Treatment of breast cancer cells with DNA demethylating agents leads to a release of Pol II stalling at genes with DNA-hypermethylated regions upstream of TSS (2011) (40)
- Cutting Edge: Histone Acetylation and Recombination at the TCRγ Locus Follows IL-7 Induction (2001) (40)
- Association of ATRX with pericentric heterochromatin and the Y chromosome of neonatal mouse spermatogonia (2008) (38)
- Control of chromatin accessibility for V(D)J recombination by interleukin‐7 (2001) (37)
- Thymic emigrants isolated by a new method possess unique phenotypic and functional properties. (2001) (37)
- Specific inhibition of lymphokine biosynthesis and autocrine growth using antisense oligonucleotides in Th1 and Th2 helper T cell clones (1988) (37)
- Lymphoid-Specific Helicase (HELLS) Is Essential for Meiotic Progression in Mouse Spermatocytes1 (2011) (34)
- Activation of AhR with nuclear IKKα regulates cancer stem-like properties in the occurrence of radioresistance (2018) (31)
- Preparing the target for the bullet (2002) (28)
- Degradation of 5hmC-marked stalled replication forks by APE1 causes genomic instability (2020) (27)
- The chromatin remodeling protein Lsh alters nucleosome occupancy at putative enhancers and modulates binding of lineage specific transcription factors (2019) (27)
- Lsh/HELLS regulates self-renewal/proliferation of neural stem/progenitor cells (2017) (27)
- Junctional diversity in signal joints from T cell receptor beta and delta loci via terminal deoxynucleotidyl transferase and exonucleolytic activity (1996) (26)
- New cytokines and receptors make their debut in San Antonio. (1991) (26)
- IL-1 is an autocrine growth factor for T cell clones. (1988) (25)
- IL-7 withdrawal induces a stress pathway activating p38 and Jun N-terminal kinases. (2002) (24)
- From cell code to gene code: cytokines and transcription factors. (1989) (23)
- Cutting edge: histone acetylation and recombination at the TCR gamma locus follows IL-7 induction. (2001) (19)
- LSH mediates gene repression through macroH2A deposition (2020) (19)
- Epigenetic Control during Lymphoid Development and Immune Responses (2003) (17)
- p53-dependent apoptosis and transcription of p21waf/cip1/sdi1 in SCID mice following gamma-irradiation. (1997) (17)
- Defective T-cell receptor gamma gene rearrangement in interleukin-7 receptor knockout mice. (1997) (17)
- An ATPase-deficient variant of the SNF2 family member HELLS shows altered dynamics at pericentromeric heterochromatin. (2015) (16)
- Lsh/HELLS is required for B lymphocyte development and immunoglobulin class switch recombination (2020) (16)
- Induction of oxidative DNA damage in u937 cells by TNF or anti-Fas stimulation. (2000) (15)
- Production of T-T hybrids from T cell clones. Direct comparison between cloned T cells and T hybridoma cells derived from them. (1988) (15)
- Defining functional domains of Ku80: DNA end binding and survival after radiation. (1999) (13)
- Cytokine knockouts. (1996) (13)
- The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation (2021) (12)
- Recombination sequence-binding protein in thymocytes undergoing T-cell receptor gene rearrangement. (1993) (12)
- Cloning Thymic Precursor Cells: Demonstration That Individual Pro-T1 Cells Have Dual T–NK Potential and Individual Pro-T2 Cells Have Dual αβ–γδ T Cell Potential (1999) (12)
- CD16 Cross-Linking Blocks Rearrangement of the TCRβ Locus and Development of αβ T Cells and Induces Development of NK Cells from Thymic Progenitors (1998) (11)
- Tethering of Lsh at the Oct4 locus promotes gene repression associated with epigenetic changes (2018) (10)
- The see-saw of differentiation: tipping the chromatin balance. (2008) (10)
- The ghosts in the machine: DNA methylation and the mystery of differentiation. (2012) (10)
- Measurement of Soluble and Membrane‐Bound Interleukin 1 Using a Fibroblast Bioassay (2000) (7)
- Modifications of histone cores and tails in V(D)J recombination (2003) (6)
- The role of interleukin-1 in the immune response (1989) (5)
- LSH catalyzes ATP-driven exchange of histone variants macroH2A1 and macroH2A2. (2021) (4)
- Independent of Fas and p 53 Pathways Cells Correlates with Bcl-2 and Bax Levels and Is Inhibition of Apoptosis of ProT 1 ,-T 2 , and-T 3 The Trophic Action of IL-7 on ProT Cells : (1998) (4)
- Seminars in cell and development biology on histone variants remodelers of H2A variants associated with heterochromatin. (2022) (3)
- IL-7 Induction Locus Follows γ Recombination at the TCR Cutting Edge : Histone Acetylation and (2001) (3)
- HELLS (Helicase, Lymphoid-Specific) (2014) (2)
- CD16 cross-linking blocks rearrangement of the TCR beta locus and development of alpha beta T cells and induces development of NK cells from thymic progenitors. (1998) (2)
- Defective TCRG gene rearrangement in interleukin-7 receptor knock out mice (1997) (1)
- and Kathrin Heterochromatin Heterochromatin Is Dependent on Intact Methylation , with Pericentromeric Association of Lsh , a Regulator of DNA (2003) (1)
- Cloning thymic precursor cells: demonstration that individual pro-T1 cells have dual T-NK potential and individual pro-T2 cells have dual alphabeta-gammadelta T cell potential. (1999) (1)
- Malignant Transformation and Epigenetics (2015) (1)
- TESTIS TISSUE ALLOGRAFTING REVEALS A PHENOTYPE OF MEIOTIC ARREST IN NEONATALLY LETHAL LSH KNOCK OUT MICE (2007) (1)
- 707 Chromatin remodeler Lymphoid-specific helicase (Lsh) is a critical determinant controlling postnatal epidermal growth, differentiation and response to injury (2016) (0)
- Deficiency of Lsh, a regulator of genomic methylation in mice, impairs hematopoiesis and promotes erythroleukemia development. (2006) (0)
- 350 Chromatin remodelling ATFase Lsh maintains DNA methylation at constitutive heterochromatin and prevents activation of silent transposable elements in epidermal keratinocytes (2019) (0)
- Lsh/HELLS regulates self-renewal/proliferation of neural stem/progenitor cells (2017) (0)
- The Relationship Between T Cells and Interleukin 1 (1989) (0)
- Survey Interleukin-7: physiological roles and mechanisms of action (1999) (0)
- 139 Heterochromatin maintenance is crucial for terminal keratinocyte differentiation and inhibition of inflammatory responses in the epidermis (2021) (0)
- Thymocytes Expressing Both αβ and γδ TCRs: Implications for Models of Lineage Commitment (1997) (0)
- Trophic Factor Withdrawal Induces a Novel Pathway: p38 MAPK Activates NHE1 Resulting in Intracellular Alkalinization, an Early Step in Apoptosis (2001) (0)
- Correction: Chromatin Remodeling Factor LSH Drives Cancer Progression by Suppressing the Activity of Fumarate Hydratase. (2022) (0)
- Third Annual Conference of the International Cytokine Society Harrogate, UK, September 12-15, 1995 (1996) (0)
- Environmental stress protection and inflammaging prevention: A novel synergistic antioxidant blend differenti- ation and inhibition of inflammatory responses in the epidermis SkinbarrierdysfunctioninitiatespsoriasisinflammationviaactivatingFPR1-ER (0)
- 107 Chromatin remodeler lymphoid-specific helicase (Lsh) regulates cytosine methylation at the DNA repeat elements and prevents autoimmune inflammation in the epidermis (2018) (0)
- IL-7 induces transcription of bcl-2 and bcl-XL and prevents mitochondrial translocation of Bax (1999) (0)
- CTCF recruits Lsh to CTCF target sites genomewide during male germline development : implications for a link between epigenetic reprogramming and BORIS, a CTCF paralogue (2004) (0)
- Activation of AhR with nuclear IKKα regulates cancer stem-like properties in the occurrence of radioresistance (2018) (0)
- Interleukin 1induction ofthec-jun promoter (1993) (0)
- silencing pathways de-repression of repeat elements and redundant epigenetic Genome-wide DNA methylation patterns in LSH mutant reveals Material Supplemental (2014) (0)
- Can pulsed wave tissue Doppler be used to evaluate regional diastolic ventricular function?: A-32 (2001) (0)
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