Kathryn L. Calame

Kathryn L. Calame's AcademicInfluence.com Rankings

Kathryn L. Calame

Biology

#11736

World Rank

#15158

Historical Rank

Microbiology

#676

World Rank

#747

Historical Rank

Immunology

#768

World Rank

#791

Historical Rank

Neuroscience

#1928

World Rank

#1984

Historical Rank

biology Degrees

Download Badge

Biology

Kathryn L. Calame's Degrees

PhD Biochemistry University of California, Berkeley
Bachelors Biochemistry University of California, Berkeley

Why Is Kathryn L. Calame Influential?

(Suggest an Edit or Addition)

(See a Problem?)

Kathryn L. Calame's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. (2002) (1056)
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. (2004) (962)
Regulation of plasma-cell development (2005) (872)
Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. (2003) (811)
Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways (1980) (714)
An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH (1980) (703)
Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. (2009) (570)
Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain (1980) (555)
Blimp-1-Dependent Repression of Pax-5 Is Required for Differentiation of B Cells to Immunoglobulin M-Secreting Plasma Cells (2002) (470)
Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. (1997) (456)
A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody (1981) (427)
Regulatory mechanisms that determine the development and function of plasma cells. (2003) (392)
Regulation and functions of Blimp-1 in T and B lymphocytes. (2008) (378)
Transcriptional repressor Blimp-1 regulates T cell homeostasis and function (2006) (369)
Commitment of B Lymphocytes to a Plasma Cell Fate Is Associated with Blimp-1 Expression In Vivo1 (2000) (348)
The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse (2005) (346)
Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors. (2009) (344)
Transcriptional Repression by Blimp-1 (PRDI-BF1) Involves Recruitment of Histone Deacetylase (2000) (332)
An analysis of genes regulated by the multi-functional transcriptional regulator Yin Yang-1. (1994) (307)
Direct Repression of prdm1 by Bcl-6 Inhibits Plasmacytic Differentiation1 (2004) (305)
Plasma cells: finding new light at the end of B cell development (2001) (303)
Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc. (1993) (276)
BLIMP-1 mediates extinction of major histocompatibility class II transactivator expression in plasma cells (2000) (248)
Ig/EBP-1: a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP. (1990) (241)
An immunoglobulin heavy-chain gene is formed by at least two recombinational events (1980) (240)
Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow (2005) (232)
Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling. (2006) (228)
Immunoglobulin heavy-chain enhancer requires one or more tissue-specific factors. (1985) (192)
Yin-yang 1 activates the c-myc promoter (1993) (190)
C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes (1995) (189)
Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch (2010) (173)
Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival (2008) (168)
Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas. (1982) (165)
BLIMP-1: trigger for differentiation of myeloid lineage (2000) (165)
Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1 (2007) (158)
B Lymphocyte-Induced Maturation Protein (Blimp)-1, IFN Regulatory Factor (IRF)-1, and IRF-2 Can Bind to the Same Regulatory Sites1 (2004) (149)
Blimp1-mediated repression of negative regulators is required for osteoclast differentiation (2010) (147)
Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors. (2007) (147)
The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development (2002) (146)
Blimp-1 Attenuates Th1 Differentiation by Repression of ifng, tbx21, and bcl6 Gene Expression (2008) (145)
Transcriptional regulation during B cell development. (1998) (144)
Ig/EBP (C/EBP gamma) is a transdominant negative inhibitor of C/EBP family transcriptional activators. (1995) (141)
CCAAT/enhancer binding protein (C/EBP) sites are required for HIV-1 replication in primary macrophages but not CD4(+) T cells. (1997) (137)
Changes in Histone Acetylation Are Associated with Differences in Accessibility of VH Gene Segments to V-DJ Recombination during B-Cell Ontogeny and Development (2003) (129)
Structural characteristics of the variable regions of immunoglobulin genes encoding a pathogenic autoantibody in murine lupus. (1990) (123)
B cell–specific loss of histone 3 lysine 9 methylation in the VH locus depends on Pax5 (2004) (120)
Repression of c-myc Is Necessary but Not Sufficient for Terminal Differentiation of B Lymphocytes In Vitro (2000) (119)
Transcriptional enhancer elements in the mouse immunoglobulin heavy chain locus. (1983) (118)
Signaling Pathways Activated by Oncogenic Forms of Abl Tyrosine Kinase* (1999) (118)
Identification of E-Box Factor TFE3 as a Functional Partner for the E2F3 Transcription Factor (2003) (117)
Transcriptional repressor ZF5 identifies a new conserved domain in zinc finger proteins. (1993) (117)
C/EBP activators are required for HIV-1 replication and proviral induction in monocytic cell lines. (1996) (116)
Induction of c-myc transcription by the v-Abl tyrosine kinase requires Ras, Raf1, and cyclin-dependent kinases. (1997) (115)
A dominant negative form of transcription activator mTFE3 created by differential splicing. (1991) (109)
A transcriptional repressor of c-myc (1989) (107)
MicroRNA-155 function in B Cells. (2007) (104)
Polyamines alter sequence-specific DNA-protein interactions. (1995) (103)
B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion (2006) (100)
Activation-dependent induction of Blimp-1. (2008) (100)
Multiple DNA sequence elements are necessary for the function of an immunoglobulin heavy chain promoter. (1987) (98)
Transcriptional regulatory cascades controlling plasma cell differentiation (2003) (96)
Repression of BCL-6 is required for the formation of human memory B cells in vitro (2007) (94)
Plasma cell differentiation and multiple myeloma. (2004) (93)
Evidence that Immunoglobulin VH-DJ Recombination Does Not Require Germ Line Transcription of the Recombining Variable Gene Segment (1998) (87)
YY1 and c-Myc associate in vivo in a manner that depends on c-Myc levels. (1996) (80)
Regulatory events in early and late B-cell differentiation. (2005) (79)
Mechanisms that regulate immunoglobulin gene expression. (1985) (78)
A transcriptional enhancer 3' of C beta 2 in the T cell receptor beta locus. (1988) (76)
The ZiN/POZ domain of ZF5 is required for both transcriptional activation and repression. (1997) (76)
Common factor 1 is a transcriptional activator which binds in the c-myc promoter, the skeletal alpha-actin promoter, and the immunoglobulin heavy-chain enhancer (1991) (72)
ICSBP/IRF-8 inhibits mitogenic activity of p210 Bcr/Abl in differentiating myeloid progenitor cells. (2003) (70)
Molecular cloning of translocations involving chromosome 15 and the immunoglobulin C alpha gene from chromosome 12 in two murine plasmacytomas. (1982) (66)
Characterization of the B lymphocyte-induced maturation protein-1 (Blimp-1) gene, mRNA isoforms and basal promoter. (2000) (63)
mTFE3, an X-linked transcriptional activator containing basic helix-loop-helix and zipper domains, utilizes the zipper to stabilize both DNA binding and multimerization (1992) (62)
The endogenous immunoglobulin heavy chain enhancer can activate tandem VH promoters separated by a large distance (1985) (61)
v-Abl activates c-myc transcription through the E2F site (1995) (60)
Blimp-1/Prdm1 Alternative Promoter Usage during Mouse Development and Plasma Cell Differentiation (2009) (59)
Monoclonal IgM rheumatoid factors bind IgG at a discontinuous epitope comprised of amino acid loops from heavy-chain constant-region domains 2 and 3. (1992) (58)
Novel protein-DNA interactions associated with increased immunoglobulin transcription in response to antigen plus interleukin-5 (1991) (57)
Mouse Cμ heavy chain immunoglobulin gene segment contains three intervening sequences separating domains (1980) (54)
Differential stability of c-myc mRNAS in a cell-free system (1988) (53)
Binding in vitro of multiple cellular proteins to immunoglobulin heavy-chain enhancer DNA (1986) (53)
Complex protein binding within the mouse immunoglobulin heavy-chain enhancer (1987) (53)
Limited expression of C/EBP family proteins during B lymphocyte development. Negative regulator Ig/EBP predominates early and activator NF-IL-6 is induced later. (1994) (51)
Transcription factors that regulate memory in humoral responses (2006) (51)
The basic helix-loop-helix-zipper domain of TFE3 mediates enhancer-promoter interaction (1994) (46)
TFE3 contains two activation domains, one acidic and the other proline-rich, that synergistically activate transcription. (1995) (43)
Metal-dependent binding of a nuclear factor to the rat metallothionein-I promoter. (1990) (43)
In vivo functional analysis of in vitro protein binding sites in the immunoglobulin heavy chain enhancer. (1988) (43)
Transcription of a minimal promoter from the NF-IL6 gene is regulated by CREB/ATF and SP1 proteins in U937 promonocytic cells. (1998) (43)
SV40 enhancer-binding factors are required at the establishment but not the maintenance step of enhancer-dependent transcriptional activation (1986) (41)
Inhibition of v-Abl transformation by p53 and p19ARF (1999) (41)
An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development. (1982) (39)
Transcriptional controlling elements in the immunoglobulin and T cell receptor loci. (1988) (38)
YY1 helps to bring loose ends together. (2007) (37)
The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitro. (1992) (36)
GATA elements are necessary for the activity and tissue specificity of the T-cell receptor beta-chain transcriptional enhancer (1994) (36)
An lmmunoglobulin Heavy Chain Variable Region Gene Is Generated from Three Segments of DNA : VH (2004) (34)
Proteins binding to site C2 (muE3) in the immunoglobulin heavy-chain enhancer exist in multiple oligomeric forms (1989) (32)
The absence of the transcription activator TFE3 impairs activation of B cells in vivo (1997) (32)
Blimp-1/PRDM1 Mediates Transcriptional Suppression of the NLR Gene NLRP12/Monarch-11 (2009) (31)
Clonal origins of lymphoproliferative disease induced by Epstein-Barr virus (1986) (31)
A plasmacytoma-specific factor binds the c-myc promoter region. (1987) (29)
TIF1beta functions as a coactivator for C/EBPbeta and is required for induced differentiation in the myelomonocytic cell line U937. (2001) (27)
Interaction of bacteriophage lambda repressor with nonoperator DNA containing single-strand gaps. (1978) (25)
Transcription factors controlling the beginning and end of B-cell differentiation. (2003) (25)
Molecular analysis of IgM rheumatoid factor binding to chimeric IgG. (1991) (24)
Direct Repression of prdm 1 by Bcl-6 Inhibits Plasmacytic Differentiation 1 (2004) (22)
Two types of DNA rearrangements in immunoglobulin genes. (1981) (21)
Translocation affects normal c-myc promoter usage and activates fifteen cryptic c-myc transcription starts in plasmacytoma M603. (1984) (21)
Purified mu EBP-E binds to immunoglobulin enhancers and promoters (1988) (21)
Immunoglobulin gene transcription: molecular mechanisms. (1989) (21)
Location of an ampicillin resistance transposon, Tn1701, in a group of small, nontransferring plasmids (1979) (20)
The C/EBP family of proteins distorts DNA upon binding but does not introduce a large directed bend. (1994) (18)
An interfering form of Blimp‐1 increases IgM secreting plasma cells and blocks maturation of peripheral B cells (2002) (18)
Introduction of genes into primary murine splenic B cells using retrovirus vectors. (2004) (18)
Lessons in transcriptional regulation learned from studies on immunoglobulin genes. (1995) (17)
Location of promoter sites on plasmid NTP1 which contains the ampicillin resistance transposon Tn1701. (1979) (16)
Immunoglobulin JH, C mu, and C gamma gene rearrangements in human B lymphocytes clonally transformed by Epstein-Barr virus. (1985) (16)
Strong transcriptional activation of translocated c-myc genes occurs without a strong nearby enhancer or promoter (1988) (16)
Alternative inducers of the rat metallothionein I gene cause distinct changes in chromatin structure in the 5' region of the gene (1986) (15)
A role for c-Abl in c-myc regulation. (1995) (14)
Multiple roles for Blimp-1 in B and T lymphocytes. (2007) (13)
An active chromatin structure acquired by translocated c-myc genes (1986) (13)
Increased Expression of Bcl-xL and c-Myc Is Associated with Transformation by Abelson Murine Leukemia Virus* (2003) (12)
Immunology: End game for B cells (2001) (12)
Role of B-lymphocyte-induced maturation protein-1 in terminal differentiation of B cells and other cell lineages. (1999) (12)
CHAPTER 6 – Transcription of Immunoglobulin Genes (2003) (12)
18 – Regulation of immunoglobulin gene transcription (1995) (12)
Inhibition of in vitro transcription by specific double-stranded oligodeoxyribonucleotides. (1990) (11)
Positive and negative regulation of c-Myc transcription. (1997) (10)
p53 Deficiency Increases Transformation by v-Abl and Rescues the Ability of a C-Terminally Truncated v-Abl Mutant To Induce Pre-B Lymphoma In Vivo (2000) (10)
Visualization of ribosome--single-stranded DNA complexes in the electron microscope. (1977) (10)
A 125 bp region of the Ig VH1 promoter is sufficient to confer lymphocyte-specific expression in transgenic mice. (1996) (10)
THE ORGANIZATION AND REARRANGEMENT OF HEAVY CHAIN IMMUNOGLOBULIN GENES IN MICE (1979) (10)
Physical location of ribosome binding sites on lambda DNA. (1977) (8)
Ig / EBP ( CIEBP ) is a transdominant negative inhibitor of C / EBP family transcriptional activators (2003) (8)
Blimp-1’s Maiden Flight (2010) (8)
v-Abl utilizes multiple mechanisms to drive G1/S progression in fibroblasts (2000) (7)
Association with c-Myc: an alternated mechanism for c-Myc function. (1995) (7)
Location of ribosome-binding sites on the tetracycline resistance transposon Tn10 (1978) (5)
Molecular cloning of translocations involving chromosome 15 and the immunoglobulin Ca gene from chromosome 12 in two murine plasmacytomas ( class switching / oncogenesis ) (5)
Electron microscope mapping of ribosome binding sites on single-stranded DNA. (1979) (3)
CCAAT y enhancer binding protein ~ C y EBP ! sites are required for HIV-1 replication in primary macrophages but not CD 4 1 T cells (1997) (3)
Activator proteins which regulate immunoglobulin heavy chain gene transcription in B lymphocytes. (1990) (3)
Expression In Vivo Cell Fate Is Associated with Blimp-1 Commitment of B Lymphocytes to a Plasma (2000) (3)
Corrigendum to “The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development” [Mech. Dev. 117 (2002) 305–309] (2002) (2)
Genetic analyses of Tattered, an X-linked dominant, developmental mouse mutation (1995) (2)
Pillars Article: An Immunoglobulin Heavy Chain Variable Region Gene Is Generated from Three Segments of DNA: VH, D and JH. Cell, 1980, 19: 981–992. (2004) (1)
Can Bind to the Same Regulatory (Blimp)-1, IFN Regulatory Factor (IRF)-1, B Lymphocyte-Induced Maturation Protein (2004) (1)
A super-gene family in the immune system. (1986) (1)
Active repression by Blimp1 play an important role in osteoclast differentiation (2012) (1)
Interaction of bacteriophage X repressor with nonoperator DNA containing single-strand gaps (1)
Contents continued (2002) (0)
A repressor of c-myc transcription is found specifically in plasmacytomas. (1988) (0)
Introduction to COI volume on lymphocyte activation 2008. (2008) (0)
Molecular cloning oftranslocations involving chromosome 15and theimmunoglobulin Cagenefromchromosome 12intwo murine plasmacytomas (1982) (0)
Regulation and Mechanism of Action of the c-Myc Proto-Oncogene in Human Breast Cancer. (1995) (0)
Alternative Inducers oftheRatMetallothionein IGeneCause Distinct Changes inChromatin Structure inthe 5'Region oftheGene (1986) (0)
TIF1 (cid:1) functions as a coactivator for C/EBP (cid:1) and is required for induced differentiation in the myelomonocytic cell line U937 (2001) (0)
Plasma cell differentiation (WS-050) Chairpersons: Takeshi Tokuhisa, Stephen Nutt (2010) (0)
Location ofRibosome-Binding Sites ontheTetracycline Resistance Transposon TnlO (1978) (0)
Faculty Opinions recommendation of Loss of Pax5 promotes plasma cell differentiation. (2006) (0)
598 The monoclonal IgM rheumatoid factor (mIgM RF) binding site: Essential amino acids in CH2 and CH3 domains of genetically engineered chimeric IgG (cIgG) (1991) (0)
Faculty Opinions recommendation of Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. (2007) (0)
An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. 1980. (2004) (0)
The immunoglobulin calpha gene from chromosome 12 in two murine plasmacytomas. (1982) (0)
Nucleic Acids Research Two types of immunoglobulin gene rearrangement occur during B-cell development (2005) (0)
Transcription factors in terminally differentiated B cells. (1988) (0)
Faculty Opinions recommendation of Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR. (2007) (0)
Faculty Opinions recommendation of Transcriptional regulator Id2 mediates CD8+ T cell immunity. (2006) (0)
Faculty Opinions recommendation of Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. (2008) (0)
Blimp‐1 directly represses il2 and the gene encoding il2 transcriptional activator Fos (2008) (0)
Transcriptional regulation of immunoglobulin heavy chain and T-cell receptor beta chain genes. (1989) (0)
Nucleic Acids Research An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development (0)

This paper list is powered by the following services:

What Schools Are Affiliated With Kathryn L. Calame?

Kathryn L. Calame is affiliated with the following schools:

Kathryn L. Calame's Academic­Influence.com Rankings

Kathryn L. Calame's Degrees

Why Is Kathryn L. Calame Influential?

Kathryn L. Calame's Published Works

Published Works

What Schools Are Affiliated With Kathryn L. Calame?

Kathryn L. Calame's AcademicInfluence.com Rankings