Kathryn L. Calame
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Kathryn L. Calamebiology Degrees
Biology
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#15158
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Microbiology
#676
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#747
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Immunology
#768
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#791
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Neuroscience
#1928
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#1984
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Biology
Kathryn L. Calame's Degrees
- PhD Biochemistry University of California, Berkeley
- Bachelors Biochemistry University of California, Berkeley
Why Is Kathryn L. Calame Influential?
(Suggest an Edit or Addition)Kathryn L. Calame's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Blimp-1 orchestrates plasma cell differentiation by extinguishing the mature B cell gene expression program. (2002) (1056)
- XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. (2004) (962)
- Regulation of plasma-cell development (2005) (872)
- Blimp-1 is required for the formation of immunoglobulin secreting plasma cells and pre-plasma memory B cells. (2003) (811)
- Two mRNAs can be produced from a single immunoglobulin μ gene by alternative RNA processing pathways (1980) (714)
- An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH (1980) (703)
- Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. (2009) (570)
- Two mRNAs with different 3′ ends encode membrane-bound and secreted forms of immunoglobulin μ chain (1980) (555)
- Blimp-1-Dependent Repression of Pax-5 Is Required for Differentiation of B Cells to Immunoglobulin M-Secreting Plasma Cells (2002) (470)
- Repression of c-myc transcription by Blimp-1, an inducer of terminal B cell differentiation. (1997) (456)
- A single VH gene segment encodes the immune response to phosphorylcholine: Somatic mutation is correlated with the class of the antibody (1981) (427)
- Regulatory mechanisms that determine the development and function of plasma cells. (2003) (392)
- Regulation and functions of Blimp-1 in T and B lymphocytes. (2008) (378)
- Transcriptional repressor Blimp-1 regulates T cell homeostasis and function (2006) (369)
- Commitment of B Lymphocytes to a Plasma Cell Fate Is Associated with Blimp-1 Expression In Vivo1 (2000) (348)
- The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse (2005) (346)
- Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors. (2009) (344)
- Transcriptional Repression by Blimp-1 (PRDI-BF1) Involves Recruitment of Histone Deacetylase (2000) (332)
- An analysis of genes regulated by the multi-functional transcriptional regulator Yin Yang-1. (1994) (307)
- Direct Repression of prdm1 by Bcl-6 Inhibits Plasmacytic Differentiation1 (2004) (305)
- Plasma cells: finding new light at the end of B cell development (2001) (303)
- Inhibition of transcriptional regulator Yin-Yang-1 by association with c-Myc. (1993) (276)
- BLIMP-1 mediates extinction of major histocompatibility class II transactivator expression in plasma cells (2000) (248)
- Ig/EBP-1: a ubiquitously expressed immunoglobulin enhancer binding protein that is similar to C/EBP and heterodimerizes with C/EBP. (1990) (241)
- An immunoglobulin heavy-chain gene is formed by at least two recombinational events (1980) (240)
- Blimp-1 is required for maintenance of long-lived plasma cells in the bone marrow (2005) (232)
- Regulation of class-switch recombination and plasma cell differentiation by phosphatidylinositol 3-kinase signaling. (2006) (228)
- Immunoglobulin heavy-chain enhancer requires one or more tissue-specific factors. (1985) (192)
- Yin-yang 1 activates the c-myc promoter (1993) (190)
- C/EBP proteins activate transcription from the human immunodeficiency virus type 1 long terminal repeat in macrophages/monocytes (1995) (189)
- Bach2 represses plasma cell gene regulatory network in B cells to promote antibody class switch (2010) (173)
- Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival (2008) (168)
- Mouse c-myc oncogene is located on chromosome 15 and translocated to chromosome 12 in plasmacytomas. (1982) (165)
- BLIMP-1: trigger for differentiation of myeloid lineage (2000) (165)
- Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1 (2007) (158)
- B Lymphocyte-Induced Maturation Protein (Blimp)-1, IFN Regulatory Factor (IRF)-1, and IRF-2 Can Bind to the Same Regulatory Sites1 (2004) (149)
- Blimp1-mediated repression of negative regulators is required for osteoclast differentiation (2010) (147)
- Class switch recombination and somatic hypermutation in early mouse B cells are mediated by B cell and Toll-like receptors. (2007) (147)
- The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development (2002) (146)
- Blimp-1 Attenuates Th1 Differentiation by Repression of ifng, tbx21, and bcl6 Gene Expression (2008) (145)
- Transcriptional regulation during B cell development. (1998) (144)
- Ig/EBP (C/EBP gamma) is a transdominant negative inhibitor of C/EBP family transcriptional activators. (1995) (141)
- CCAAT/enhancer binding protein (C/EBP) sites are required for HIV-1 replication in primary macrophages but not CD4(+) T cells. (1997) (137)
- Changes in Histone Acetylation Are Associated with Differences in Accessibility of VH Gene Segments to V-DJ Recombination during B-Cell Ontogeny and Development (2003) (129)
- Structural characteristics of the variable regions of immunoglobulin genes encoding a pathogenic autoantibody in murine lupus. (1990) (123)
- B cell–specific loss of histone 3 lysine 9 methylation in the VH locus depends on Pax5 (2004) (120)
- Repression of c-myc Is Necessary but Not Sufficient for Terminal Differentiation of B Lymphocytes In Vitro (2000) (119)
- Transcriptional enhancer elements in the mouse immunoglobulin heavy chain locus. (1983) (118)
- Signaling Pathways Activated by Oncogenic Forms of Abl Tyrosine Kinase* (1999) (118)
- Identification of E-Box Factor TFE3 as a Functional Partner for the E2F3 Transcription Factor (2003) (117)
- Transcriptional repressor ZF5 identifies a new conserved domain in zinc finger proteins. (1993) (117)
- C/EBP activators are required for HIV-1 replication and proviral induction in monocytic cell lines. (1996) (116)
- Induction of c-myc transcription by the v-Abl tyrosine kinase requires Ras, Raf1, and cyclin-dependent kinases. (1997) (115)
- A dominant negative form of transcription activator mTFE3 created by differential splicing. (1991) (109)
- A transcriptional repressor of c-myc (1989) (107)
- MicroRNA-155 function in B Cells. (2007) (104)
- Polyamines alter sequence-specific DNA-protein interactions. (1995) (103)
- B-1 B lymphocytes require Blimp-1 for immunoglobulin secretion (2006) (100)
- Activation-dependent induction of Blimp-1. (2008) (100)
- Multiple DNA sequence elements are necessary for the function of an immunoglobulin heavy chain promoter. (1987) (98)
- Transcriptional regulatory cascades controlling plasma cell differentiation (2003) (96)
- Repression of BCL-6 is required for the formation of human memory B cells in vitro (2007) (94)
- Plasma cell differentiation and multiple myeloma. (2004) (93)
- Evidence that Immunoglobulin VH-DJ Recombination Does Not Require Germ Line Transcription of the Recombining Variable Gene Segment (1998) (87)
- YY1 and c-Myc associate in vivo in a manner that depends on c-Myc levels. (1996) (80)
- Regulatory events in early and late B-cell differentiation. (2005) (79)
- Mechanisms that regulate immunoglobulin gene expression. (1985) (78)
- A transcriptional enhancer 3' of C beta 2 in the T cell receptor beta locus. (1988) (76)
- The ZiN/POZ domain of ZF5 is required for both transcriptional activation and repression. (1997) (76)
- Common factor 1 is a transcriptional activator which binds in the c-myc promoter, the skeletal alpha-actin promoter, and the immunoglobulin heavy-chain enhancer (1991) (72)
- ICSBP/IRF-8 inhibits mitogenic activity of p210 Bcr/Abl in differentiating myeloid progenitor cells. (2003) (70)
- Molecular cloning of translocations involving chromosome 15 and the immunoglobulin C alpha gene from chromosome 12 in two murine plasmacytomas. (1982) (66)
- Characterization of the B lymphocyte-induced maturation protein-1 (Blimp-1) gene, mRNA isoforms and basal promoter. (2000) (63)
- mTFE3, an X-linked transcriptional activator containing basic helix-loop-helix and zipper domains, utilizes the zipper to stabilize both DNA binding and multimerization (1992) (62)
- The endogenous immunoglobulin heavy chain enhancer can activate tandem VH promoters separated by a large distance (1985) (61)
- v-Abl activates c-myc transcription through the E2F site (1995) (60)
- Blimp-1/Prdm1 Alternative Promoter Usage during Mouse Development and Plasma Cell Differentiation (2009) (59)
- Monoclonal IgM rheumatoid factors bind IgG at a discontinuous epitope comprised of amino acid loops from heavy-chain constant-region domains 2 and 3. (1992) (58)
- Novel protein-DNA interactions associated with increased immunoglobulin transcription in response to antigen plus interleukin-5 (1991) (57)
- Mouse Cμ heavy chain immunoglobulin gene segment contains three intervening sequences separating domains (1980) (54)
- Differential stability of c-myc mRNAS in a cell-free system (1988) (53)
- Binding in vitro of multiple cellular proteins to immunoglobulin heavy-chain enhancer DNA (1986) (53)
- Complex protein binding within the mouse immunoglobulin heavy-chain enhancer (1987) (53)
- Limited expression of C/EBP family proteins during B lymphocyte development. Negative regulator Ig/EBP predominates early and activator NF-IL-6 is induced later. (1994) (51)
- Transcription factors that regulate memory in humoral responses (2006) (51)
- The basic helix-loop-helix-zipper domain of TFE3 mediates enhancer-promoter interaction (1994) (46)
- TFE3 contains two activation domains, one acidic and the other proline-rich, that synergistically activate transcription. (1995) (43)
- Metal-dependent binding of a nuclear factor to the rat metallothionein-I promoter. (1990) (43)
- In vivo functional analysis of in vitro protein binding sites in the immunoglobulin heavy chain enhancer. (1988) (43)
- Transcription of a minimal promoter from the NF-IL6 gene is regulated by CREB/ATF and SP1 proteins in U937 promonocytic cells. (1998) (43)
- SV40 enhancer-binding factors are required at the establishment but not the maintenance step of enhancer-dependent transcriptional activation (1986) (41)
- Inhibition of v-Abl transformation by p53 and p19ARF (1999) (41)
- An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development. (1982) (39)
- Transcriptional controlling elements in the immunoglobulin and T cell receptor loci. (1988) (38)
- YY1 helps to bring loose ends together. (2007) (37)
- The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitro. (1992) (36)
- GATA elements are necessary for the activity and tissue specificity of the T-cell receptor beta-chain transcriptional enhancer (1994) (36)
- An lmmunoglobulin Heavy Chain Variable Region Gene Is Generated from Three Segments of DNA : VH (2004) (34)
- Proteins binding to site C2 (muE3) in the immunoglobulin heavy-chain enhancer exist in multiple oligomeric forms (1989) (32)
- The absence of the transcription activator TFE3 impairs activation of B cells in vivo (1997) (32)
- Blimp-1/PRDM1 Mediates Transcriptional Suppression of the NLR Gene NLRP12/Monarch-11 (2009) (31)
- Clonal origins of lymphoproliferative disease induced by Epstein-Barr virus (1986) (31)
- A plasmacytoma-specific factor binds the c-myc promoter region. (1987) (29)
- TIF1beta functions as a coactivator for C/EBPbeta and is required for induced differentiation in the myelomonocytic cell line U937. (2001) (27)
- Interaction of bacteriophage lambda repressor with nonoperator DNA containing single-strand gaps. (1978) (25)
- Transcription factors controlling the beginning and end of B-cell differentiation. (2003) (25)
- Molecular analysis of IgM rheumatoid factor binding to chimeric IgG. (1991) (24)
- Direct Repression of prdm 1 by Bcl-6 Inhibits Plasmacytic Differentiation 1 (2004) (22)
- Two types of DNA rearrangements in immunoglobulin genes. (1981) (21)
- Translocation affects normal c-myc promoter usage and activates fifteen cryptic c-myc transcription starts in plasmacytoma M603. (1984) (21)
- Purified mu EBP-E binds to immunoglobulin enhancers and promoters (1988) (21)
- Immunoglobulin gene transcription: molecular mechanisms. (1989) (21)
- Location of an ampicillin resistance transposon, Tn1701, in a group of small, nontransferring plasmids (1979) (20)
- The C/EBP family of proteins distorts DNA upon binding but does not introduce a large directed bend. (1994) (18)
- An interfering form of Blimp‐1 increases IgM secreting plasma cells and blocks maturation of peripheral B cells (2002) (18)
- Introduction of genes into primary murine splenic B cells using retrovirus vectors. (2004) (18)
- Lessons in transcriptional regulation learned from studies on immunoglobulin genes. (1995) (17)
- Location of promoter sites on plasmid NTP1 which contains the ampicillin resistance transposon Tn1701. (1979) (16)
- Immunoglobulin JH, C mu, and C gamma gene rearrangements in human B lymphocytes clonally transformed by Epstein-Barr virus. (1985) (16)
- Strong transcriptional activation of translocated c-myc genes occurs without a strong nearby enhancer or promoter (1988) (16)
- Alternative inducers of the rat metallothionein I gene cause distinct changes in chromatin structure in the 5' region of the gene (1986) (15)
- A role for c-Abl in c-myc regulation. (1995) (14)
- Multiple roles for Blimp-1 in B and T lymphocytes. (2007) (13)
- An active chromatin structure acquired by translocated c-myc genes (1986) (13)
- Increased Expression of Bcl-xL and c-Myc Is Associated with Transformation by Abelson Murine Leukemia Virus* (2003) (12)
- Immunology: End game for B cells (2001) (12)
- Role of B-lymphocyte-induced maturation protein-1 in terminal differentiation of B cells and other cell lineages. (1999) (12)
- CHAPTER 6 – Transcription of Immunoglobulin Genes (2003) (12)
- 18 – Regulation of immunoglobulin gene transcription (1995) (12)
- Inhibition of in vitro transcription by specific double-stranded oligodeoxyribonucleotides. (1990) (11)
- Positive and negative regulation of c-Myc transcription. (1997) (10)
- p53 Deficiency Increases Transformation by v-Abl and Rescues the Ability of a C-Terminally Truncated v-Abl Mutant To Induce Pre-B Lymphoma In Vivo (2000) (10)
- Visualization of ribosome--single-stranded DNA complexes in the electron microscope. (1977) (10)
- A 125 bp region of the Ig VH1 promoter is sufficient to confer lymphocyte-specific expression in transgenic mice. (1996) (10)
- THE ORGANIZATION AND REARRANGEMENT OF HEAVY CHAIN IMMUNOGLOBULIN GENES IN MICE (1979) (10)
- Physical location of ribosome binding sites on lambda DNA. (1977) (8)
- Ig / EBP ( CIEBP ) is a transdominant negative inhibitor of C / EBP family transcriptional activators (2003) (8)
- Blimp-1’s Maiden Flight (2010) (8)
- v-Abl utilizes multiple mechanisms to drive G1/S progression in fibroblasts (2000) (7)
- Association with c-Myc: an alternated mechanism for c-Myc function. (1995) (7)
- Location of ribosome-binding sites on the tetracycline resistance transposon Tn10 (1978) (5)
- Molecular cloning of translocations involving chromosome 15 and the immunoglobulin Ca gene from chromosome 12 in two murine plasmacytomas ( class switching / oncogenesis ) (5)
- Electron microscope mapping of ribosome binding sites on single-stranded DNA. (1979) (3)
- CCAAT y enhancer binding protein ~ C y EBP ! sites are required for HIV-1 replication in primary macrophages but not CD 4 1 T cells (1997) (3)
- Activator proteins which regulate immunoglobulin heavy chain gene transcription in B lymphocytes. (1990) (3)
- Expression In Vivo Cell Fate Is Associated with Blimp-1 Commitment of B Lymphocytes to a Plasma (2000) (3)
- Corrigendum to “The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development” [Mech. Dev. 117 (2002) 305–309] (2002) (2)
- Genetic analyses of Tattered, an X-linked dominant, developmental mouse mutation (1995) (2)
- Pillars Article: An Immunoglobulin Heavy Chain Variable Region Gene Is Generated from Three Segments of DNA: VH, D and JH. Cell, 1980, 19: 981–992. (2004) (1)
- Can Bind to the Same Regulatory (Blimp)-1, IFN Regulatory Factor (IRF)-1, B Lymphocyte-Induced Maturation Protein (2004) (1)
- A super-gene family in the immune system. (1986) (1)
- Active repression by Blimp1 play an important role in osteoclast differentiation (2012) (1)
- Interaction of bacteriophage X repressor with nonoperator DNA containing single-strand gaps (1)
- Contents continued (2002) (0)
- A repressor of c-myc transcription is found specifically in plasmacytomas. (1988) (0)
- Introduction to COI volume on lymphocyte activation 2008. (2008) (0)
- Molecular cloning oftranslocations involving chromosome 15and theimmunoglobulin Cagenefromchromosome 12intwo murine plasmacytomas (1982) (0)
- Regulation and Mechanism of Action of the c-Myc Proto-Oncogene in Human Breast Cancer. (1995) (0)
- Alternative Inducers oftheRatMetallothionein IGeneCause Distinct Changes inChromatin Structure inthe 5'Region oftheGene (1986) (0)
- TIF1 (cid:1) functions as a coactivator for C/EBP (cid:1) and is required for induced differentiation in the myelomonocytic cell line U937 (2001) (0)
- Plasma cell differentiation (WS-050) Chairpersons: Takeshi Tokuhisa, Stephen Nutt (2010) (0)
- Location ofRibosome-Binding Sites ontheTetracycline Resistance Transposon TnlO (1978) (0)
- Faculty Opinions recommendation of Loss of Pax5 promotes plasma cell differentiation. (2006) (0)
- 598 The monoclonal IgM rheumatoid factor (mIgM RF) binding site: Essential amino acids in CH2 and CH3 domains of genetically engineered chimeric IgG (cIgG) (1991) (0)
- Faculty Opinions recommendation of Transcription factors T-bet and Runx3 cooperate to activate Ifng and silence Il4 in T helper type 1 cells. (2007) (0)
- An immunoglobulin heavy chain variable region gene is generated from three segments of DNA: VH, D and JH. 1980. (2004) (0)
- The immunoglobulin calpha gene from chromosome 12 in two murine plasmacytomas. (1982) (0)
- Nucleic Acids Research Two types of immunoglobulin gene rearrangement occur during B-cell development (2005) (0)
- Transcription factors in terminally differentiated B cells. (1988) (0)
- Faculty Opinions recommendation of Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR. (2007) (0)
- Faculty Opinions recommendation of Transcriptional regulator Id2 mediates CD8+ T cell immunity. (2006) (0)
- Faculty Opinions recommendation of Transcription factor EBF restricts alternative lineage options and promotes B cell fate commitment independently of Pax5. (2008) (0)
- Blimp‐1 directly represses il2 and the gene encoding il2 transcriptional activator Fos (2008) (0)
- Transcriptional regulation of immunoglobulin heavy chain and T-cell receptor beta chain genes. (1989) (0)
- Nucleic Acids Research An immunoglobulin promoter region is unaltered by DNA rearrangement and somatic mutation during B-cell development (0)
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