Kathryn Ayscough
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Professor of Molecular Cell Biology
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Kathryn Ayscoughbiology Degrees
Biology
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Cell Biology
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Molecular Biology
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Biology
Kathryn Ayscough's Degrees
- PhD Molecular Cell Biology University of California, Berkeley
- Bachelors Biology Stanford University
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Why Is Kathryn Ayscough Influential?
(Suggest an Edit or Addition)According to Wikipedia, Kathryn Rachel Ayscough is a professor of molecular cell biology and head of the department of biomedical science at the University of Sheffield. She was awarded the 2002 Society for Experimental Biology President's Medal. Her research investigates the role of the actin cytoskeleton in membrane trafficking and cell organisation.
Kathryn Ayscough's Published Works
Published Works
- High Rates of Actin Filament Turnover in Budding Yeast and Roles for Actin in Establishment and Maintenance of Cell Polarity Revealed Using the Actin Inhibitor Latrunculin-A (1997) (755)
- Latrunculin alters the actin-monomer subunit interface to prevent polymerization (2000) (496)
- The actin cytoskeleton: a key regulator of apoptosis and ageing? (2005) (383)
- A role for the actin cytoskeleton in cell death and aging in yeast (2004) (289)
- Under Pressure: the Differential Requirements for Actin during Yeast and Mammalian Endocytosis (2009) (221)
- Actin-binding proteins (2005) (220)
- Actin regulation in endocytosis (2006) (206)
- In vivo functions of actin-binding proteins. (1998) (199)
- Actin-Induced Hyperactivation of the Ras Signaling Pathway Leads to Apoptosis in Saccharomyces cerevisiae (2006) (146)
- Sla1p couples the yeast endocytic machinery to proteins regulating actin dynamics. (2002) (129)
- Guidelines and recommendations on yeast cell death nomenclature (2018) (129)
- Identification of an upstream regulatory pathway controlling actin-mediated apoptosis in yeast (2005) (125)
- Functions of actin in endocytosis (2009) (120)
- A role for the dynamin-like protein Vps1 during endocytosis in yeast (2010) (119)
- Endocytosis and the development of cell polarity in yeast require a dynamic F-actin cytoskeleton (2000) (103)
- A role for the yeast actin cytoskeleton in pheromone receptor clustering and signalling (1998) (97)
- A role for actin in aging and apoptosis. (2005) (95)
- The Ark1/Prk1 family of protein kinases (2003) (90)
- Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast (2009) (89)
- A Role for the Actin Cytoskeleton of Saccharomyces cerevisiae in Bipolar Bud-Site Selection (1997) (87)
- The actin cytoskeleton in ageing and apoptosis. (2005) (86)
- Sla1p is a functionally modular component of the yeast cortical actin cytoskeleton required for correct localization of both Rho1p-GTPase and Sla2p, a protein with talin homology. (1999) (84)
- Use of latrunculin-A, an actin monomer-binding drug. (1998) (76)
- An interaction between Sla1p and Sla2p plays a role in regulating actin dynamics and endocytosis in budding yeast (2003) (74)
- The Ark1/Prk1 family of protein kinases. Regulators of endocytosis and the actin skeleton. (2003) (65)
- ACTIN: general principles from studies in yeast. (1996) (63)
- Miconazole Induces Changes in Actin Cytoskeleton prior to Reactive Oxygen Species Induction in Yeast* (2007) (62)
- Apoptosis in yeast – mechanisms and benefits to a unicellular organism (2006) (61)
- Depletion of the actin bundling protein SM22/transgelin increases actin dynamics and enhances the tumourigenic phenotypes of cells (2012) (60)
- SCP1 encodes an actin-bundling protein in yeast. (2003) (57)
- Modulation of cell spreading and cell-substrate adhesion dynamics by dystroglycan (2010) (55)
- Novel proteins linking the actin cytoskeleton to the endocytic machinery in Saccharomyces cerevisiae. (2002) (54)
- Yeast Dynamin Vps1 and Amphiphysin Rvs167 Function Together During Endocytosis (2012) (53)
- A Dynamin-Actin Interaction Is Required for Vesicle Scission during Endocytosis in Yeast (2015) (47)
- Amino acid substitution equivalent to human chorea-acanthocytosis I2771R in yeast Vps13 protein affects its binding to phosphatidylinositol 3-phosphate (2017) (42)
- Interactions between the Yeast SM22 Homologue Scp1 and Actin Demonstrate the Importance of Actin Bundling in Endocytosis*S⃞ (2008) (41)
- The WASP homologue Las17 activates the novel actin-regulatory activity of Ysc84 to promote endocytosis in yeast. (2009) (37)
- Yeast Arf3p Modulates Plasma Membrane PtdIns(4,5)P2 Levels to Facilitate Endocytosis (2008) (37)
- Endocytosis: Actin in the Driving Seat (2004) (37)
- Coupling actin dynamics to the endocytic process in Saccharomyces cerevisiae (2005) (36)
- Dynamin-SNARE interactions control trans-SNARE formation in intracellular membrane fusion (2013) (35)
- A Novel Actin-Binding Motif in Las17/WASP Nucleates Actin Filaments Independently of Arp2/3 (2013) (34)
- Membrane Rafts Are Involved in Intracellular Miconazole Accumulation in Yeast Cells* (2009) (33)
- Yeast Endocytic Adaptor AP-2 Binds the Stress Sensor Mid2 and Functions in Polarized Cell Responses (2014) (32)
- Lsb5p interacts with actin regulators Sla1p and Las17p, ubiquitin and Arf3p to couple actin dynamics to membrane trafficking processes. (2005) (28)
- Disruption of the plant-specific CFS1 gene impairs autophagosome turnover and triggers EDS1-dependent cell death (2017) (23)
- WASP family proteins, more than Arp2/3 activators (2016) (23)
- Phosphatidylinositol-3-phosphate regulates response of cells to proteotoxic stress. (2016) (22)
- Nucleocytoplasmic Trafficking Is Required for Functioning of the Adaptor Protein Sla1p in Endocytosis (2007) (19)
- An Abp1-Dependent Route of Endocytosis Functions when the Classical Endocytic Pathway in Yeast Is Inhibited (2014) (18)
- Forty years on: clathrin-coated pits continue to fascinate (2017) (16)
- Phosphorylation Regulates the Endocytic Function of the Yeast Dynamin-Related Protein Vps1 (2015) (15)
- Interactions between Sla1p, Lsb5p and Arf3p in yeast endocytosis. (2005) (14)
- Methyl beta-cyclodextrin reduces accumulation of reactive oxygen species and cell death in yeast. (2009) (13)
- AP-2-Dependent Endocytic Recycling of the Chitin Synthase Chs3 Regulates Polarized Growth in Candida albicans (2019) (13)
- Expression of Vps1 I649K, a self-assembly defective yeast dynamin, leads to formation of extended endocytic invaginations (2011) (13)
- Yeast-model-based study identified myosin- and calcium-dependent calmodulin signalling as a potential target for drug intervention in chorea-acanthocytosis (2019) (13)
- Apm4, the mu subunit of yeast AP-2 interacts with Pkc1, and mutation of the Pkc1 consensus phosphorylation site Thr176 inhibits AP-2 recruitment to endocytic sites (2014) (10)
- The yeast actin cytoskeleton and its function in endocytosis (2010) (9)
- Defining Protein Modules for Endocytosis (2005) (8)
- Distinct Actin and Lipid Binding Sites in Ysc84 Are Required during Early Stages of Yeast Endocytosis (2015) (8)
- The Pex3–Inp1 complex tethers yeast peroxisomes to the plasma membrane (2020) (7)
- Elucidating Key Motifs Required for Arp2/3-Dependent and Independent Actin Nucleation by Las17/WASP (2016) (6)
- Two billion years of actin (2004) (6)
- Function and interactions of the Ysc84/SH3yl1 family of actin- and lipid-binding proteins. (2015) (5)
- Insights into dynamin-associated disorders through analysis of equivalent mutations in the yeast dynamin Vps1 (2016) (4)
- A Charge Swap mutation E461K in the yeast dynamin Vps1 reduces endocytic invagination (2015) (4)
- Two billion years of actin. Meeting on cytoskeletal dynamics: from cell biology to developmental disease. (2004) (3)
- Mutation of key lysine residues in the Insert B region of the yeast dynamin Vps1 disrupts lipid binding and causes defects in endocytosis (2019) (3)
- F1000Prime recommendation of Actin dynamics provides membrane tension to merge fusing vesicles into the plasma membrane. (2016) (2)
- Interactions between Sla 1 p , Lsb 5 p and Arf 3 p in yeast endocytosis (2005) (1)
- A Ruthenium(II) Polypyridyl Complex Disrupts Actin Cytoskeleton Assembly and Blocks Cytokinesis (2022) (1)
- Depletion of the actin bundling protein SM22/transgelin increases actin dynamics and enhances the tumourigenic phenotypes of cells (2012) (1)
- Faculty Opinions recommendation of A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits. (2019) (0)
- Movies for minimal dataset. Smaczynska-de Rooij PLoS One 2019 (2019) (0)
- 11 Immunological Methods (2007) (0)
- meeting meeting report Two billion years of actin Meeting on Cytoskeletal Dynamics: From Cell Biology to Development and Disease (2004) (0)
- Faculty Opinions recommendation of Yersinia effector YopO uses actin as bait to phosphorylate proteins that regulate actin polymerization. (2015) (0)
- The AP-2 endocytic adaptor complex in Candida albicans morphology and virulence (2019) (0)
- Phosphorylation of the WH2 domain in yeast Las17/WASP regulates G-actin binding and protein function during endocytosis (2021) (0)
- Ultra-structural analysis of the role of yeast dynamin like protein Vps1 (2011) (0)
- Faculty Opinions recommendation of A bilirubin-inducible fluorescent protein from eel muscle. (2013) (0)
- Faculty Opinions recommendation of Formins determine the functional properties of actin filaments in yeast. (2014) (0)
- The dynamin Vps1 mediates Atg9 transport to the sites of autophagosome formation. (2023) (0)
- Faculty Opinions recommendation of Actin filament elongation in Arp2/3-derived networks is controlled by three distinct mechanisms. (2013) (0)
- Disruption of the plant-specific CFS1 gene impairs autophagosome turnover and triggers EDS1-dependent cell death (2017) (0)
- Faculty Opinions recommendation of Patchwork organization of the yeast plasma membrane into numerous coexisting domains. (2012) (0)
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