Kathy K. Griendling
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Engineering Biology
Kathy K. Griendling's Degrees
- PhD Biomedical Engineering University of California, Berkeley
- Masters Biomedical Engineering University of California, Berkeley
- Bachelors Biomedical Engineering University of California, Berkeley
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(Suggest an Edit or Addition)Kathy K. Griendling's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- NAD(P)H oxidase: role in cardiovascular biology and disease. (2000) (3014)
- Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells. (1994) (2802)
- Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone. (1996) (2517)
- Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system. (2007) (1785)
- Cell transformation by the superoxide-generating oxidase Mox1 (1999) (1498)
- Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor (1991) (1224)
- Reactive oxygen species in the vasculature: molecular and cellular mechanisms. (2003) (1017)
- Modulation of Protein Kinase Activity and Gene Expression by Reactive Oxygen Species and Their Role in Vascular Physiology and Pathophysiology (2000) (988)
- Oxidative Stress and Cardiovascular Injury: Part I: Basic Mechanisms and In Vivo Monitoring of ROS (2003) (915)
- Novel gp91phox Homologues in Vascular Smooth Muscle Cells: nox1 Mediates Angiotensin II-Induced Superoxide Formation and Redox-Sensitive Signaling Pathways (2001) (911)
- Superoxide Production and Expression of Nox Family Proteins in Human Atherosclerosis (2002) (871)
- Reactive Oxygen Species in Metabolic and Inflammatory Signaling. (2018) (841)
- Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets (2011) (837)
- p22phox Is a Critical Component of the Superoxide-generating NADH/NADPH Oxidase System and Regulates Angiotensin IIinduced Hypertrophy in Vascular Smooth Muscle Cells* (1996) (809)
- Oxidative stress and cardiovascular injury: Part II: animal and human studies. (2003) (787)
- Nox proteins in signal transduction. (2009) (777)
- Angiotensin II Stimulation of NAD(P)H Oxidase Activity: Upstream Mediators (2002) (760)
- Increased NADH-oxidase-mediated superoxide production in the early stages of atherosclerosis: evidence for involvement of the renin-angiotensin system. (1999) (740)
- Role of oxidative stress in atherosclerosis. (2003) (731)
- The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. (2003) (723)
- Effects of Angiotensin II Infusion on the Expression and Function of NAD(P)H Oxidase and Components of Nitric Oxide/cGMP Signaling (2002) (690)
- Biochemistry, Physiology, and Pathophysiology of NADPH Oxidases in the Cardiovascular System (2012) (680)
- Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase. (1998) (659)
- Role of NADH/NADPH oxidase-derived H2O2 in angiotensin II-induced vascular hypertrophy. (1998) (645)
- Distinct Subcellular Localizations of Nox1 and Nox4 in Vascular Smooth Muscle Cells (2004) (604)
- Reactive Oxygen Species Mediate the Activation of Akt/Protein Kinase B by Angiotensin II in Vascular Smooth Muscle Cells* (1999) (595)
- p38 Mitogen-activated Protein Kinase Is a Critical Component of the Redox-sensitive Signaling Pathways Activated by Angiotensin II (1998) (594)
- p22phox mRNA expression and NADPH oxidase activity are increased in aortas from hypertensive rats. (1997) (590)
- NADPH Oxidases: Functions and Pathologies in the Vasculature (2010) (575)
- Direct Interaction of the Novel Nox Proteins with p22phox Is Required for the Formation of a Functionally Active NADPH Oxidase* (2004) (538)
- Measurement of reactive oxygen species in cardiovascular studies. (2007) (475)
- Molecular Biology of the Renin‐Angiotensin System (1993) (470)
- Upregulation of Nox‐Based NAD(P)H Oxidases in Restenosis After Carotid Injury (2002) (460)
- Oxidative stress and diabetic cardiovascular complications. (2006) (453)
- Reactive oxygen species as mediators of angiotensin II signaling (2000) (436)
- Sustained diacylglycerol formation from inositol phospholipids in angiotensin II-stimulated vascular smooth muscle cells. (1986) (425)
- Nox1 Overexpression Potentiates Angiotensin II-Induced Hypertension and Vascular Smooth Muscle Hypertrophy in Transgenic Mice (2005) (416)
- Reactive oxygen species, mitochondria, and NAD(P)H oxidases in the development and progression of heart failure. (2002) (416)
- Poldip2, a Novel Regulator of Nox4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells (2009) (412)
- Angiotensin II signaling in vascular smooth muscle. New concepts. (1997) (409)
- Bone Morphogenic Protein 4 Produced in Endothelial Cells by Oscillatory Shear Stress Induces Monocyte Adhesion by Stimulating Reactive Oxygen Species Production From a Nox1-Based NADPH Oxidase (2004) (387)
- Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production. (2008) (375)
- Regulation of Signal Transduction by Reactive Oxygen Species in the Cardiovascular System (2015) (374)
- Reactive oxygen species in hypertension; An update. (2004) (352)
- Reactive oxygen species signaling in vascular smooth muscle cells. (2006) (349)
- NADPH oxidases and angiotensin II receptor signaling (2009) (345)
- Basic mechanisms of oxidative stress and reactive oxygen species in cardiovascular injury. (2007) (341)
- Pulsatile Versus Oscillatory Shear Stress Regulates NADPH Oxidase Subunit Expression: Implication for Native LDL Oxidation (2003) (325)
- Nox4 Is Required for Maintenance of the Differentiated Vascular Smooth Muscle Cell Phenotype (2007) (318)
- Tumour necrosis factor alpha activates a p22phox-based NADH oxidase in vascular smooth muscle. (1998) (303)
- Epidermal growth factor receptor transactivation by angiotensin II requires reactive oxygen species in vascular smooth muscle cells. (2001) (299)
- Overexpression of Akt converts radial growth melanoma to vertical growth melanoma. (2007) (278)
- Oscillatory shear stress stimulates endothelial production of O2- from p47phox-dependent NAD(P)H oxidases, leading to monocyte adhesion. (2003) (277)
- Peroxisome proliferator-activated receptor-gamma ligands regulate endothelial membrane superoxide production. (2005) (273)
- Angiotensin receptors and their therapeutic implications. (1996) (261)
- Oxidative stress and cardiovascular disease. (1997) (253)
- Modulation of vascular smooth muscle signaling by reactive oxygen species. (2006) (251)
- Measurement of Reactive Oxygen Species, Reactive Nitrogen Species, and Redox-Dependent Signaling in the Cardiovascular System: A Scientific Statement From the American Heart Association. (2016) (243)
- Nox2-induced production of mitochondrial superoxide in angiotensin II-mediated endothelial oxidative stress and hypertension. (2014) (239)
- Redox signaling, vascular function, and hypertension. (2008) (236)
- Mechanisms of Vascular Smooth Muscle NADPH Oxidase 1 (Nox1) Contribution to Injury-Induced Neointimal Formation (2009) (234)
- Oxidases and peroxidases in cardiovascular and lung disease: new concepts in reactive oxygen species signaling. (2011) (230)
- Endothelin stimulates diacylglycerol accumulation and activates protein kinase C in cultured vascular smooth muscle cells. (1989) (229)
- Novel NAD(P)H oxidases in the cardiovascular system (2004) (228)
- Angiotensin II type 1 receptor: relationship with caveolae and caveolin after initial agonist stimulation. (1998) (222)
- Modulation of extracellular superoxide dismutase expression by angiotensin II and hypertension. (1999) (213)
- Redox control of vascular smooth muscle proliferation. (1998) (210)
- Angiotensin II down-regulates the vascular smooth muscle AT1 receptor by transcriptional and post-transcriptional mechanisms: evidence for homologous and heterologous regulation. (1995) (201)
- NAD(P)H oxidase-derived reactive oxygen species as mediators of angiotensin II signaling. (2002) (195)
- Cyclic strain induces an oxidative stress in endothelial cells. (1997) (190)
- Interactions of angiotensin II with NAD(P)H oxidase, oxidant stress and cardiovascular disease. (2003) (177)
- Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling. (2010) (173)
- Endothelial control of the cardiovascular system: recent advances (1996) (168)
- Phosphoinositide-Dependent Kinase 1 and p21-Activated Protein Kinase Mediate Reactive Oxygen Species–Dependent Regulation of Platelet-Derived Growth Factor–Induced Smooth Muscle Cell Migration (2004) (167)
- Vascular Hypertrophy in Angiotensin II–Induced Hypertension Is Mediated by Vascular Smooth Muscle Cell–Derived H2O2 (2005) (164)
- Nox5 mediates PDGF-induced proliferation in human aortic smooth muscle cells. (2008) (163)
- Dual role of reactive oxygen species in vascular growth. (1999) (161)
- NADPH Oxidase Inhibitors: New Antihypertensive Agents? (2007) (156)
- Cholesterol Depletion Inhibits Epidermal Growth Factor Receptor Transactivation by Angiotensin II in Vascular Smooth Muscle Cells (2001) (151)
- Correlation of receptor sequestration with sustained diacylglycerol accumulation in angiotensin II-stimulated cultured vascular smooth muscle cells. (1987) (150)
- C242T CYBA Polymorphism of the NADPH Oxidase Is Associated With Reduced Respiratory Burst in Human Neutrophils (2004) (145)
- Reactive oxygen species, NADPH oxidases, and hypertension. (2010) (140)
- Angiotensin II-induced hypertension increases heme oxygenase-1 expression in rat aorta. (1997) (139)
- Nox4 NAD(P)H Oxidase Mediates Src-dependent Tyrosine Phosphorylation of PDK-1 in Response to Angiotensin II (2008) (139)
- RNA Silencing In Vivo Reveals Role of p22phox in Rat Angiotensin Slow Pressor Response (2006) (137)
- Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes. (2007) (135)
- Hydrogen peroxide-induced c-fos expression is mediated by arachidonic acid release: role of protein kinase C. (1993) (134)
- Hydrogen peroxide stimulates transcription of c-jun in vascular smooth muscle cells: role of arachidonic acid. (1993) (133)
- Role of p38 MAPK and MAPKAPK-2 in angiotensin II-induced Akt activation in vascular smooth muscle cells. (2004) (132)
- Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells. (2002) (127)
- Differential effects of diabetes on the expression of the gp91phox homologues nox1 and nox4. (2005) (125)
- Angiotensin II stimulates phosphorylation of high-molecular-mass cytosolic phospholipase A2 in vascular smooth-muscle cells. (1994) (118)
- Temporal Dispersion of Activation of Phospholipase C-β1 and -γ Isoforms by Angiotensin II in Vascular Smooth Muscle Cells (1998) (116)
- Thrombin signal transduction mechanisms in rat vascular smooth muscle cells. Calcium and protein kinase C-dependent and -independent pathways. (1990) (116)
- Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22phox in vascular smooth muscle. (2005) (114)
- Mechanisms of Reactive Oxygen Species–Dependent Downregulation of Insulin Receptor Substrate-1 by Angiotensin II (2005) (109)
- Cytochrome b-558 α-subunit cloning and expression in rat aortic smooth muscle cells (1995) (106)
- Phosphatidylcholine is a major source of phosphatidic acid and diacylglycerol in angiotensin II-stimulated vascular smooth-muscle cells. (1993) (104)
- Electron spin resonance characterization of the NAD(P)H oxidase in vascular smooth muscle cells. (2001) (103)
- RhoA/Rho kinase mediates TGF-β1-induced kidney myofibroblast activation through Poldip2/Nox4-derived reactive oxygen species. (2014) (102)
- Prevention of Abdominal Aortic Aneurysm by Anti–MicroRNA-712 or Anti–MicroRNA-205 in Angiotensin II–Infused Mice (2014) (102)
- Characterization of phosphatidylinositol-specific phospholipase C from cultured vascular smooth muscle cells. (1991) (102)
- NADH/NADPH Oxidase and Vascular Function. (1997) (101)
- Specific regulation of RGS2 messenger RNA by angiotensin II in cultured vascular smooth muscle cells. (2000) (99)
- Angiotensin II receptor coupling to phospholipase D is mediated by the betagamma subunits of heterotrimeric G proteins in vascular smooth muscle cells. (1999) (99)
- Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice. (2005) (97)
- Angiotensin II-induced phosphatidylcholine hydrolysis in cultured vascular smooth-muscle cells. Regulation and localization. (1991) (94)
- Angiotensin II Stimulation of Vascular Smooth Muscle (1989) (93)
- Convergence of redox-sensitive and mitogen-activated protein kinase signaling pathways in tumor necrosis factor-alpha-mediated monocyte chemoattractant protein-1 induction in vascular smooth muscle cells. (2000) (92)
- Nox1-based NADPH oxidase-derived superoxide is required for VSMC activation by advanced glycation end-products. (2007) (92)
- Pyk2- and Src-Dependent Tyrosine Phosphorylation of PDK1 Regulates Focal Adhesions (2003) (89)
- Role of the Multidrug Resistance Protein-1 in Hypertension and Vascular Dysfunction Caused by Angiotensin II (2007) (89)
- Arachidonic acid metabolites mediate angiotensin II-induced NADH/NADPH oxidase activity and hypertrophy in vascular smooth muscle cells. (1999) (87)
- Mechanism of hydrogen peroxide-induced cell cycle arrest in vascular smooth muscle. (2002) (87)
- Functional association of nox1 with p22phox in vascular smooth muscle cells. (2004) (86)
- Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat. (2007) (86)
- Thrombin-stimulated events in cultured vascular smooth-muscle cells. (1991) (85)
- Anti-Inflammatory and Antiatherogenic Role of BMP Receptor II in Endothelial Cells (2013) (84)
- NADPH oxidase 4 mediates TGF-β-induced smooth muscle α-actin via p38MAPK and serum response factor. (2011) (83)
- Angiotensin II and NADPH Oxidase Increase ADMA in Vascular Smooth Muscle Cells (2010) (81)
- Redox control of vascular smooth muscle migration. (2010) (78)
- Muscle : fundamental biology and mechanisms of disease (2012) (77)
- Angiotensin II receptor pharmacology. (1994) (71)
- Pregnancy-induced changes in sheep uterine and carotid arteries. (1985) (71)
- Redox regulation of the actin cytoskeleton and its role in the vascular system (2017) (70)
- Adventitial Cells Do Not Contribute to Neointimal Mass After Balloon Angioplasty of the Rat Common Carotid Artery (2001) (69)
- Stimulation of Cellular Signaling and G Protein Subunit Dissociation by G Protein βγ Subunit-binding Peptides* (2003) (68)
- The Pickering Lecture British Hypertension Society, 10th September 2002 (2003) (66)
- Agonist-induced phosphorylation of the vascular type 1 angiotensin II receptor. (1994) (66)
- Dual Regulation of Cofilin Activity by LIM Kinase and Slingshot-1L Phosphatase Controls Platelet-Derived Growth Factor–Induced Migration of Human Aortic Smooth Muscle Cells (2008) (64)
- Resveratrol increases serine15-phosphorylated but transcriptionally impaired p53 and induces a reversible DNA replication block in serum-activated vascular smooth muscle cells. (2003) (64)
- Prolonged exposure to agonist results in a reduction in the levels of the Gq/G11 alpha subunits in cultured vascular smooth muscle cells. (1996) (63)
- Heme oxygenase-1 is regulated by angiotensin II in rat vascular smooth muscle cells. (1997) (63)
- Out, damned dot: studies of the NADPH oxidase in atherosclerosis. (2001) (62)
- Role in Cardiovascular Biology and Disease (2000) (61)
- NADPH oxidases: new regulators of old functions. (2006) (59)
- Reactive Oxygen Species in Hypertension (2004) (58)
- p22 phox Is a Critical Component of the Superoxide-generating NADH/NADPH Oxidase System and Regulates Angiotensin IIinduced Hypertrophy in Vascular Smooth Muscle Cells* (1996) (58)
- Temporal dispersion of activation of phospholipase C-beta1 and -gamma isoforms by angiotensin II in vascular smooth muscle cells. Role of alphaq/11, alpha12, and beta gamma G protein subunits. (1998) (57)
- Angiotensin II Stimulation of Vascular Smooth Muscle Phosphoinositide Metabolism State of the Art Lecture (1987) (56)
- Functional evaluation of nonphagocytic NAD(P)H oxidases. (2002) (56)
- Detection of reactive oxygen species and nitric oxide in vascular cells and tissues: comparison of sensitivity and specificity. (2007) (56)
- Resveratrol Inhibits Angiotensin II- and Epidermal Growth Factor-Mediated Akt Activation: Role of Gab1 and Shp2 (2005) (55)
- Polymerase Delta Interacting Protein 2 Sustains Vascular Structure and Function (2013) (53)
- Expression of Inducible Nitric-oxide Synthase and Intracellular Protein Tyrosine Nitration in Vascular Smooth Muscle Cells (2003) (52)
- Career development of physician scientists: a survey of leaders in academic medicine. (2011) (52)
- G Protein-coupled Receptor Kinase 5 in Cultured Vascular Smooth Muscle Cells and Rat Aorta (1997) (51)
- Angiotensin II stimulation of vascular smooth muscle cells. Secondary signalling mechanisms. (1989) (51)
- Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization. (2014) (51)
- Zinc regulates Nox1 expression through a NF‐&kgr;B and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells (2017) (50)
- NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis. (2016) (49)
- Differential roles of NADPH oxidases in vascular physiology and pathophysiology. (2012) (47)
- The effects of sepsis on endothelium and clinical implications. (2020) (46)
- Cytochrome b-558 alpha-subunit cloning and expression in rat aortic smooth muscle cells. (1995) (46)
- Effects of glucocorticoids on Na+/H+ exchange and growth in cultured vascular smooth muscle cells (1988) (45)
- Differential effects of AT1 receptor and Ca2+ channel blockade on atherosclerosis, inflammatory gene expression, and production of reactive oxygen species. (2007) (44)
- GTP gamma S loading of endothelial cells stimulates phospholipase C and uncouples ATP receptors. (1988) (44)
- Vascular thrombin receptor regulation in hypertensive rats. (1997) (44)
- Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer (2018) (44)
- Reactive Oxygen Species Sensitivity of Angiotensin II-dependent Translation Initiation in Vascular Smooth Muscle Cells* (2003) (43)
- Oxidative Stress and Hypertension (2021) (43)
- Insulin-Like Growth Factor-1 Receptor Expression Masks the Antiinflammatory and Glucose Uptake Capacity of Insulin in Vascular Smooth Muscle Cells (2009) (42)
- Poldip 2 , a Novel Regulator of Nox 4 and Cytoskeletal Integrity in Vascular Smooth Muscle Cells (2009) (41)
- Angiotensin II, From Vasoconstrictor to Growth Factor: A Paradigm Shift (2014) (41)
- Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy (2019) (40)
- Poldip2 Knockout Results in Perinatal Lethality, Reduced Cellular Growth and Increased Autophagy of Mouse Embryonic Fibroblasts (2014) (40)
- Increased Expression of Nox1 in Neointimal Smooth Muscle Cells Promotes Activation of Matrix Metalloproteinase-9 (2012) (39)
- NADPH oxidases: molecular understanding finally reaching the clinical level? (2009) (38)
- Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass. (2012) (38)
- Transforming Growth Factor β Inhibits Platelet Derived Growth Factor-Induced Vascular Smooth Muscle Cell Proliferation via Akt-Independent, Smad-Mediated Cyclin D1 Downregulation (2013) (37)
- The A640G and C242T p22(phox) polymorphisms in patients with coronary artery disease. (2002) (37)
- Oxidative stress and diabetic vascular complications (2004) (37)
- Angiotensin II induces phosphorylation of eukaryotic protein synthesis initiation factor 4E in vascular smooth muscle cells. (1994) (36)
- Cholera toxin modulation of angiotensin II-stimulated inositol phosphate production in cultured vascular smooth muscle cells. (1990) (35)
- Platelet-derived Growth Factor (PDGF) Regulates Slingshot Phosphatase Activity via Nox1-dependent Auto-dephosphorylation of Serine 834 in Vascular Smooth Muscle Cells* (2011) (34)
- Mechanical stretch augments insulin-induced vascular smooth muscle cell proliferation by insulin-like growth factor-1 receptor. (2011) (31)
- Stimulation of cellular signaling and G protein subunit dissociation by G protein betagamma subunit-binding peptides. (2003) (30)
- Evidence that Na+/H+ exchange regulates angiotensin II-stimulated diacylglycerol accumulation in vascular smooth muscle cells. (1988) (29)
- Dimethylarginine dimethylaminohydrolase (DDAH): expression, regulation, and function in the cardiovascular and renal systems (2007) (28)
- VE-cadherin endocytosis controls vascular integrity and patterning during development (2019) (28)
- The bone morphogenic protein inhibitor, noggin, reduces glycemia and vascular inflammation in db/db mice. (2013) (26)
- SECONDARY SIGNALLING MECHANISMS IN ANGIOTENSIN II‐STIMULATED VASCULAR SMOOTH MUSCLE CELLS (1988) (26)
- Cholesterol depletion inhibits epidermal growth factor receptor transactivation by angiotensin II in vascular smooth muscle cells. ROLE OF CHOLESTEROL-RICH MICRODOMAINS AND FOCAL ADHESIONS IN ANGIOTENSIN II SIGNALING. (2013) (25)
- Angiotensin II stimulates vimentin phosphorylation via a Ca2+-dependent, protein kinase C-independent mechanism in cultured vascular smooth muscle cells. (1988) (25)
- G-Protein binding domains of the angiotensin II AT1A receptors mapped with synthetic peptides selected from the receptor sequence. (1998) (23)
- Polymerase &dgr;-interacting Protein 2: A Multifunctional Protein (2017) (23)
- Role of Coronin 1B in PDGF-Induced Migration of Vascular Smooth Muscle Cells (2012) (23)
- Hydrogen Peroxide Regulates Osteopontin Expression through Activation of Transcriptional and Translational Pathways* (2013) (23)
- Relation between alpha adrenergic receptor occupation and contractile response: radioligand and physiologic studies in canine aorta. (1984) (23)
- Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4. (2017) (21)
- Molecular Biology of Angiotensin II Receptors (1994) (21)
- The angiotensin (AT1) receptor. (1993) (20)
- Redox-Sensitive Regulation of Myocardin-Related Transcription Factor (MRTF-A) Phosphorylation via Palladin in Vascular Smooth Muscle Cell Differentiation Marker Gene Expression (2016) (20)
- Polymerase &dgr;-Interacting Protein 2 Promotes Postischemic Neovascularization of the Mouse Hindlimb (2014) (19)
- Signal transduction in vascular smooth muscle. (1996) (19)
- Regional differences in alpha 1-adrenoceptor numbers and responses in canine aorta. (1984) (18)
- β1 and β2 integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammation. (2020) (18)
- NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase &dgr;-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion (2018) (18)
- Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p 22 phox in vascular smooth muscle (2004) (17)
- Superoxide and hydrogen peroxide counterregulate myogenic contractions in renal afferent arterioles from a mouse model of chronic kidney disease. (2017) (17)
- Oscillatory Shear Stress Stimulates Endothelial Production of \batchmode \documentclass[fleqn,10pt,legalpaper]{article} \usepackage{amssymb} \usepackage{amsfonts} \usepackage{amsmath} \pagestyle{empty} \begin{document} \(\mathrm{O}_{2}^{-}\) \end{document} from p47phox-dependent NAD(P)H Oxidases, Le (2003) (17)
- ATVB in focus: redox mechanisms in blood vessels. (2004) (17)
- Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain (2018) (17)
- Severe Acute Respiratory Syndrome Coronavirus 2, COVID-19, and the Renin-Angiotensin System (2020) (17)
- Hydrogen peroxide down-regulates inositol 1,4,5-trisphosphate receptor content through proteasome activation. (2009) (17)
- Hic-5 Mediates TGF&bgr;–Induced Adhesion in Vascular Smooth Muscle Cells by a Nox4-Dependent Mechanism (2015) (17)
- High Salt Enhances Reactive Oxygen Species and Angiotensin II Contractions of Glomerular Afferent Arterioles From Mice With Reduced Renal Mass (2018) (16)
- Prominent Contribution of Hydrogen Peroxide to Intracellular Reactive Oxygen Species Generated upon Exposure to Naphthalene Secondary Organic Aerosols (2020) (15)
- Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells. (2016) (15)
- The Vascular Angiotensin (AT1) Receptor (1993) (15)
- Muscarinic cholinergic stimulation of inositol phosphate production in cultured embryonic chick atrial cells. Evidence for a role of two guanine-nucleotide-binding proteins. (1990) (14)
- Angiotensin-ll- and Endothelin-lnduced Protein Phosphorylation in Cultured Vascular Smooth Muscle Cells (1993) (13)
- NADPH oxidases: progress and opportunities. (2014) (13)
- Potassium depletion selectively inhibits sustained diacylglycerol formation from phosphatidylinositol in angiotensin II-stimulated, cultured vascular smooth muscle cells. (1987) (13)
- Poldip2 deficiency protects against lung edema and vascular inflammation in a model of acute respiratory distress syndrome. (2019) (13)
- Tumour necrosis factor α activates a p 22 phox-based NADH oxidase in vascular smooth muscle (1998) (12)
- Vascular smooth muscle insulin resistance, but not hypertrophic signaling, is independent of angiotensin II-induced IRS-1 phosphorylation by JNK. (2011) (12)
- The Yin/Yang of superoxide dismutase mimetics: potential cardiovascular therapies? (2003) (11)
- Angiotensin II Receptor Coupling to Phospholipase D Is Mediated by the bg Subunits of Heterotrimeric G Proteins in Vascular Smooth Muscle Cells (1998) (11)
- Poldip2 Knockdown Inhibits Vascular Smooth Muscle Proliferation and Neointima Formation by Regulating the Expression of PCNA and p21 (2018) (11)
- Angiotensin-II-and endothelin-induced protein phosphorylation in cultured vascular smooth muscle cells. (1993) (10)
- NADPH Oxidases and Measurement of Reactive Oxygen Species. (2017) (10)
- Endothelin A and B Receptors Are Down‐Regulated in the Hearts of Hypertensive Rats (1994) (10)
- An acceleration in hypertension-related mortality for middle-aged and older Americans, 1999-2016: An observational study (2020) (10)
- Oscillatory Shear Stress Stimulates Endothelial Production of O 2 from p47 phox -dependent NAD(P)H Oxidases, Leading to (2003) (10)
- Lack of Long-Term Protective Effect of Antioxidant/Anti-Inflammatory Therapy in Transplant-Induced Ischemia/Reperfusion Injury (2006) (10)
- Cyclic Strain and Hypertension Increase Osteopontin Expression in the Aorta (2017) (9)
- Nox is playing with a full deck in vascular smooth muscle, a commentary on "Noxa1 is a central component of the smooth muscle NADPH oxidase in mice". (2006) (8)
- Relationship of phospholipase C‐ and phospholipase D‐mediated phospholipid remodeling pathways to respiratory burst activation in human neutrophils stimulated by Candida albicans hyphae (1995) (8)
- Out phoxing the endothelium: what's left without p47? (2002) (8)
- The Role of Oxidative Stress in Hypertension (2000) (7)
- Poldip2 controls leukocyte infiltration into the ischemic brain by regulating focal adhesion kinase-mediated VCAM-1 induction (2021) (7)
- Polymerase-δ-interacting protein 2 activates the RhoGEF epithelial cell transforming sequence 2 in vascular smooth muscle cells. (2019) (7)
- Effects of Angiotensin II Infusion on the Expression and Function of NAD(P)H Oxidase (2002) (7)
- Development of muscarinic-cholinergic stimulation of inositol phosphate production in cultured embryonic chick atrial cells. Evidence for a switch in guanine-nucleotide-binding protein coupling. (1990) (6)
- Resveratrol Increases Serine 15 -Phosphorylated but Transcriptionally Impaired p53 and Induces a Reversible DNA Replication Block in Serum-Activated Vascular Smooth Muscle Cells (2003) (6)
- Transforming Growth Factor β Inhibits Platelet Derived Growth Factor-Induced Vascular Smooth Muscle Cell Proliferation via Akt-Independent , Smad-Mediated Cyclin D 1 Downregulation (6)
- Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation. (2021) (5)
- Increased Expression of Nox 1 in Neointimal Smooth Muscle Cells Promotes Activation of Matrix Metalloproteinase-9 (2012) (5)
- Oxidative Stress and Cardiovascular Disease in Diabetes Mellitus (2010) (5)
- Monitoring of ROS Oxidative Stress and Cardiovascular Injury: Part I: Basic Mechanisms and In Vivo (2010) (5)
- Mycophenolic acid is a new Nox2 inhibitor. (2007) (4)
- Redox control of growth factor signaling in heart, lung, and circulation. (2003) (4)
- FGF Suppresses Poldip2 Expression in Osteoblasts (2017) (4)
- Nuclear factor (erythroid-derived 2)-like 2, the brake in oxidative stress that nicotinamide adenine dinucleotide phosphate-oxidase-4 needs to protect the heart. (2015) (4)
- Mitochondrial Respiration and Atherosclerosis: R-E-S-P-I-R-E. Find Out What it Means to Mϕ (and VSMC). (2017) (4)
- Erratum: Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression and p22phox in mice (American Journal of Physiology - Heart and Circulatory Physiology (January 2005) 288 (H7-H12)) (2005) (3)
- Evidence for Involvement of the Renin-Angiotensin System Mediated Superoxide Production in the Early Stages of − Increased NADH-Oxidase (1999) (3)
- 2004 CARDIOVASCULAR AND KIDNEY INVESTIGATORS MEETING Biology of Free Radicals Angiotensin II-induced hypertrophy is potentiated in mice overexpressing p22 phox in vascular smooth muscle (2005) (3)
- Specific Regulation of RGS 2 Messenger RNA by Angiotensin II in Cultured Vascular Smooth Muscle Cells (2000) (3)
- Fundamental Cardiovascular Research: Returns on Societal Investment: A Scientific Statement From the American Heart Association. (2017) (3)
- The interdependent effects of cholesterol and substrate stiffness on vascular smooth muscle cell biomechanics. (2019) (3)
- Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting (2021) (3)
- NADPH Oxidase 1 Mediates Acute Blood Pressure Response to Angiotensin II by Contributing to Calcium Influx in Vascular Smooth Muscle Cells (2022) (3)
- Abstract 18285: Poldip2, a Nox4 Interacting Protein, Regulates Vascular Smooth Muscle Cell Migration via RhoA-Dependent Focal Adhesion Turnover (2010) (2)
- Poldip 2 Knockout Results in Perinatal Lethality , Reduced Cellular Growth and Increased Autophagy of Mouse Embryonic Fibroblasts (2)
- Role of Coronin 1 B in PDGF-Induced Migration of Vascular Smooth Muscle Cells (2012) (2)
- Platelet microRNAs and vascular injury. (2019) (2)
- Myeloid Poldip2 Contributes to the Development of Pulmonary Inflammation by Regulating Neutrophil Adhesion in a Murine Model of Acute Respiratory Distress Syndrome (2022) (2)
- Chapter 3 – Vascular Smooth Muscle (2013) (2)
- Hypertension Highlights Reactive Oxygen Species, NADPH Oxidases, and Hypertension (2010) (2)
- Thrombin: beyond coagulation. (2004) (2)
- Cardiovascular-Renal Mechanisms in Health and Disease Reactive oxygen species-selective regulation of aortic inflammatory gene expression in Type 2 diabetes (2007) (2)
- Notice of retraction. (2020) (2)
- Pathogenesis of Hypertension: Vascular Mechanisms (2003) (2)
- Angiotensin AT1 receptors (2006) (2)
- 365 – TGF-β Mediates Focal Adhesion Maturation by a Smad/Nox4-Dependent Mechanism that Involves Regulation of Hsp27 and Hic5 (2013) (2)
- PDGF‐induced Vascular Smooth Muscle Cell Migration is Regulated by Coronin 1b (2010) (1)
- Discovery and Therapeutic Relevance of Small-Molecule Nox4 Inhibitors (2018) (1)
- Circulation Research Editors’ Yearly Report: 2001 (2002) (1)
- Chemiluminescence and the Nox1-Nox2-Nox4 Triple Knockout. (2015) (1)
- Celltransformationbythesuperoxide-generating oxidase Mox 1 (1)
- Abstract 1368: Overexpression of P22phox Subunit of Nadph Oxidase in Mice Accelerates Cardiac Fibrosis and Angiogenesis in Response to Angiotensin Ii (2008) (0)
- Abstract 77: MicroRNA-34a Accelerates Aging in Vascular Smooth Muscle Cells (SMCs) Isolated from Transgenic Mice Overexpressing Nox1 in SMCs (2013) (0)
- Oxidative Stress and Cardiovascular Injury Part II: Animal and Human Studies Review: Clinical Cardiology: New Frontiers (2003) (0)
- Abstract 5473: TGF{beta} Induction of Vascular Smooth Muscle Differentiation Markers is Mediated by Nox4 and p38 Mitogen-activated Protein Kinase (2009) (0)
- Nox1‐mediated activation of Slingshot phosphatase in VSMC (2010) (0)
- Correction: Platelet-derived growth factor (PDGF) regulates slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells. (2020) (0)
- Angiotensin II Signaling in Vascular Physiology and Pathophysiology (2008) (0)
- senescencehypertension and accelerated renal Association of mitochondrial SOD deficiency with (2015) (0)
- Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain (2018) (0)
- 364 - Role of βPIX in PDGF-Induced Lamellipodia Dynamics in VSMC (2013) (0)
- vascular smooth muscle cells Angiotensin II stimulates NADH and NADPH oxidase activity in cultured (2005) (0)
- Angiotensin 11 stimulates phosphorylation of high-molecular-mass cytosolic phospholipase A2 in vascular smooth-muscle cells (2005) (0)
- Abstract 17016: The Role of Polymerase Delta-Interacting Protein 2 in Pulmonary Vascular Inflammation (2018) (0)
- Reply to Bailey et al.: New perspectives on the novel role of the Poldip2/ACSM1 axis in a functional mammalian lipoylation salvage pathway (2018) (0)
- Tempol prevents the enhancement of angiotensin II contractions of afferent arterioles from mouse with reduced renal mass (2017) (0)
- Role of NADPH oxidases in vascular biology and disease (2002) (0)
- Abstract 051: High Salt Enhances ROS and Ang II Contractions of Glomerular Afferent Arterioles From Mice With Reduced Renal Mass (2018) (0)
- Poldip2 controls leukocyte infiltration into the ischemic brain by regulating focal adhesion kinase-mediated VCAM-1 induction (2021) (0)
- Mitochondrial ATP-Sensitive Potassium Channel Regulates Cytoplasmic NADPH Oxidase Activity through Mitochondrial Superoxide (2010) (0)
- Abstract 060: POLDIP-2/NOX-4 Generates Hydrogen Peroxide that Impairs Myogenic Response of Afferent Arterioles from Mice with the Reduced Renal Mass Model of Chronic Kidney Disease (2015) (0)
- Abstract 16013: The Role of Poldip2/NOX4 in Redox Regulation of Actin During Integrin-Mediated Cell Adhesion (2017) (0)
- Role of NADPH Oxidases in Blood–Brain Barrier Disruption and Ischemic Stroke (2022) (0)
- Supplementation with Tetrahydrobiopterin Reverse Impaired Endothelium-Dependent Relaxation and eNOS Uncoupling Induced by Nox1 Overexpression in Vascular Smooth Muscle (2010) (0)
- Abstract 140: Anti-inflammatory and Anti-atherogenic Role of Bmp Receptor II In Endothelial Cells (2013) (0)
- Abstract TP110: Polymerase δ-Interacting Protein 2 Regulates Astrocyte Activation in Ischemic Stroke (2016) (0)
- Role of oxidant mechanisms in hypertension (1997) (0)
- Molecular Pathways of Smooth Muscle Disease (2012) (0)
- 5 Angiotensin II, Oxidative Stress, (1998) (0)
- Novel Mechanism by Which Extracellular Cyclic GMP Induces Natriuresis. (2023) (0)
- NAD(P)H Oxidases as Mediators of Angiotensin II-induced Vascular Responses(Recent Advance in the Role of Renin-Angiotensin-Aldosterone System in Atherosclerotic Vascular Disease, The 69th Annual Scientific Meeting of the Japanese Circulation Society) (2005) (0)
- Kathy Griendling: a modest molecular biologist. Interview by Ruth Williams. (2011) (0)
- Redox Mechanisms in Blood Vessels (2005) (0)
- Cyclic Strain and Hypertension Increase Osteopontin Expression in the Aorta (2016) (0)
- Role of Nox2-induced Reverse Electron Transfer in Production of Mitochondrial Reactive Oxygen Species, Endothelial Dysfunction and Hypertension (2010) (0)
- Abstract 553: Relaxin Attenuates Angiotensin II--Induced Proinflammatory Signaling in Vascular Smooth Muscle Cells (2014) (0)
- The Effects of Smooth Muscle‐Targeted Nox1‐Overexpression in the Development of Hypoxia‐Mediated Pulmonary Hypertension (2006) (0)
- Endothelium-Vascular Smooth Muscle Interactions in Culture (1987) (0)
- Poldip2 Activates the Rho Guanine Nucleotide Exchange Factor Ect2 To Regulate Vascular Smooth Muscle Cell Proliferation (2017) (0)
- Angiotensin II, Oxidative Stress, and Nitric Oxide (1998) (0)
- Poldip2 Affects Collagen I Accumulation by Regulating the Expression of Zyxin in Vascular Smooth Muscle Cells (2018) (0)
- Profiles in Cardiovascular Science (2011) (0)
- Doris Duke Charitable Foundation Fund to Retain Clinical Scientists: innovating support for early-career family caregivers (2022) (0)
- Regulation of the ADMA/PRMT/DDAH pathway in vascular smooth muscle cells by the p22phox component of NADPH oxidase (2009) (0)
- Angiotensin II-induced hypertension activates hemoxygenase-1 expression in the rat aorta (1997) (0)
- NADPH Oxidases as Mediators of Vascular Physiology (2012) (0)
- Accelerated vascular aging in aldosterone associated hypertension: role of NADPH oxidase 1 and implications for cardiovascular complications (2015) (0)
- Abstract 693: Nox4 Mediates Cardiac Fibrosis while p47phox-based Nox2 is Required for the Inflammatory Response to Angiotensin II in Murine Cardiac Fibroblasts (2006) (0)
- Redox Modification of the Cytoskeleton During Cell Adhesion and Migration (2018) (0)
- pathophysiologyendothelial senescence: from mechanisms to (2015) (0)
- Nox4, Poldip2 and vascular function (2018) (0)
- Abstract 11759: Poldip 2 Regulates Adhesion and Spreading of Vascular Smooth Muscle Cells Through Its Interaction With Kindlin-2 and Talin (2012) (0)
- Regulation of cytoplasmic NADPH oxidase by mitochondrial ATP‐sensitive potassium channel and mitochondrial superoxide (2011) (0)
- Editorial Board (2012) (0)
- Vasoconstrictor-mediated ionic events associated with sustained contractile responses in cultured vascular smooth muscle cells (1987) (0)
- Adhesions Phosphorylation of PDK 1 Regulates Focal Pyk 2-and Src-Dependent Tyrosine (2003) (0)
- Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy (2019) (0)
- Reactive Oxygen Species Modulation of Vascular Smooth Muscle Signaling by (2016) (0)
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What Schools Are Affiliated With Kathy K. Griendling?
Kathy K. Griendling is affiliated with the following schools:
