Katja Becker
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German biochemist
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Why Is Katja Becker Influential?
(Suggest an Edit or Addition)According to Wikipedia, Katja Becker is a German physician and biochemist who has been serving as the president of the German Research Foundation since 2020. She had previously been the organization's vice president from 2014 to 2019.
Katja Becker's Published Works
Published Works
- The endophytic fungus Piriformospora indica reprograms barley to salt-stress tolerance, disease resistance, and higher yield. (2005) (1188)
- Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions. (2004) (585)
- Substitution of the thioredoxin system for glutathione reductase in Drosophila melanogaster. (2001) (399)
- The thioredoxin system—From science to clinic (2004) (379)
- Human Placenta Thioredoxin Reductase (1998) (375)
- Thioredoxin reductase as a pathophysiological factor and drug target. (2000) (353)
- Thioredoxin reductase two modes of catalysis have evolved. (2000) (311)
- On the potential of thioredoxin reductase inhibitors for cancer therapy. (2006) (308)
- The Thioredoxin System of the Malaria Parasite Plasmodium falciparum (2000) (241)
- Methylene blue as an antimalarial agent (2003) (204)
- The mechanism of thioredoxin reductase from human placenta is similar to the mechanisms of lipoamide dehydrogenase and glutathione reductase and is distinct from the mechanism of thioredoxin reductase from Escherichia coli. (1997) (203)
- Enzyme inactivation through sulfhydryl oxidation by physiologic NO-carriers (1998) (158)
- Undressing of phosphine gold(I) complexes as irreversible inhibitors of human disulfide reductases. (2006) (156)
- Interactions of Methylene Blue with Human Disulfide Reductases and Their Orthologues from Plasmodium falciparum (2007) (154)
- Compartmentation of Redox Metabolism in Malaria Parasites (2010) (150)
- The Putative Glutathione Peroxidase Gene of Plasmodium falciparum Codes for a Thioredoxin Peroxidase* (2001) (149)
- Human thioredoxin reductase is efficiently inhibited by (2,2':6',2' '-terpyridine)platinum(II) complexes. Possible implications for a novel antitumor strategy. (2001) (131)
- Glutathione – Functions and Metabolism in the Malarial Parasite Plasmodium falciparum (2003) (126)
- Glutathione S-Transferase of the Malarial Parasite Plasmodium falciparum: Characterization of a Potential Drug Target (2002) (123)
- Crystal Structure of the Antioxidant Enzyme Glutathione Reductase Inactivated by Peroxynitrite* (2002) (122)
- Recombinant Plasmodium falciparum glutathione reductase is inhibited by the antimalarial dye methylene blue (1998) (122)
- Glutathione reductase of the malarial parasite Plasmodium falciparum: crystal structure and inhibitor development. (2003) (121)
- A prodrug form of a Plasmodium falciparum glutathione reductase inhibitor conjugated with a 4-anilinoquinoline. (2001) (117)
- Thioredoxin and glutathione systems in Plasmodium falciparum. (2012) (111)
- The thioredoxin specificity of Drosophila GPx: a paradigm for a peroxiredoxin-like mechanism of many glutathione peroxidases. (2007) (107)
- Crystal structure of the human thioredoxin reductase-thioredoxin complex. (2011) (106)
- In Vitro Assessment of Methylene Blue on Chloroquine-Sensitive and -Resistant Plasmodium falciparum Strains Reveals Synergistic Action with Artemisinins (2005) (104)
- A hypothesis on the catalytic mechanism of the selenoenzyme thioredoxin reductase. (1998) (101)
- The structure of human thioredoxin reductase 1 provides insights into C-terminal rearrangements during catalysis. (2007) (98)
- Plasmodium falciparum Possesses a Classical Glutaredoxin and a Second, Glutaredoxin-like Protein with a PICOT Homology Domain* (2001) (97)
- Protein S-glutathionylation in malaria parasites. (2011) (97)
- Ethaselen: a potent mammalian thioredoxin reductase 1 inhibitor and novel organoselenium anticancer agent. (2012) (95)
- Optimization of a whole-cell biocatalyst by employing genetically encoded product sensors inside nanolitre reactors. (2015) (90)
- The malarial parasite Plasmodium falciparum imports the human protein peroxiredoxin 2 for peroxide detoxification (2009) (89)
- Thioredoxin networks in the malarial parasite Plasmodium falciparum. (2006) (89)
- Crystal structure of a novel Plasmodium falciparum 1-Cys peroxiredoxin. (2005) (87)
- Antioxidant Status and Nitric Oxide in the Malnutrition Syndrome Kwashiorkor (2001) (86)
- X-ray structure of glutathione S-transferase from the malarial parasite Plasmodium falciparum (2003) (84)
- Inhibition of human glutathione reductase by S-nitrosoglutathione. (1995) (83)
- The Drosophila Carbonyl Reductase Sniffer Prevents Oxidative Stress-Induced Neurodegeneration (2004) (83)
- From andesitic volcanism to the formation of a porphyry Cu-Au mineralizing magma chamber: the Farallón Negro Volcanic Complex, northwestern Argentina (2004) (82)
- Identification and Characterization of Heme-interacting Proteins in the Malaria Parasite, Plasmodium falciparum* (2003) (81)
- The Thioredoxin System — From Science to Clinic (2004) (80)
- Diversity of Chemical Mechanisms in Thioredoxin Catalysis Revealed by Single-Molecule Force Spectroscopy (2009) (80)
- Plasmodium falciparum--do killers commit suicide? (2004) (79)
- Mechanistic Studies on a Novel, Highly Potent Gold-Phosphole Inhibitor of Human Glutathione Reductase* (2005) (78)
- Mitochondrial and Cytoplasmic Thioredoxin Reductase Variants Encoded by a Single Drosophila Gene Are Both Essential for Viability* (2002) (77)
- Selective antimicrobial activity associated with sulfur nanoparticles. (2011) (76)
- Identification of Proteins Targeted by the Thioredoxin Superfamily in Plasmodium falciparum (2009) (74)
- The Plasmodium selenoproteome (2006) (73)
- The thioredoxin system of Plasmodium falciparum and other parasites (2002) (72)
- Thioredoxin peroxidases of the malarial parasite Plasmodium falciparum. (2001) (69)
- Large-Scale Differential Proteome Analysis in Plasmodium falciparum under Drug Treatment (2008) (68)
- Effect of surface roughness, porosity, and a resorbable calcium phosphate coating on osseointegration of titanium in a minipig model. (2009) (67)
- Dinitrosyl-dithiol-iron complexes, nitric oxide (NO) carriers in vivo, as potent inhibitors of human glutathione reductase and glutathione-S-transferase. (1997) (66)
- Exploring synthetic avenues for the effective synthesis of selenium- and tellurium-containing multifunctional redox agents. (2009) (66)
- Plasmodium falciparum glutathione S‐transferase—Structural and mechanistic studies on ligand binding and enzyme inhibition (2006) (65)
- HIPK2 kinase activity depends on cis-autophosphorylation of its activation loop. (2013) (64)
- Human placenta thioredoxin reductase: preparation and inhibitor studies. (2002) (64)
- Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2 (2010) (64)
- Infectious diseases – A global challenge (2006) (64)
- Specific inhibitors of Plasmodium falciparum thioredoxin reductase as potential antimalarial agents. (2006) (63)
- The 58 kDa mouse selenoprotein is a BCNU‐sensitive thioredoxin reductase (1997) (61)
- Mechanism-based inactivation of thioredoxin reductase from Plasmodium falciparum by Mannich bases. Implication for cytotoxicity. (2003) (58)
- Intracellular Positioning of Isoforms Explains an Unusually Large Adenylate Kinase Gene Family in the Parasite Trypanosoma brucei*[boxs] (2005) (57)
- Kinetic Characterization of Glutathione Reductase from the Malarial Parasite Plasmodium falciparum (2000) (57)
- Recombinant putative glutathione reductase of Plasmodium falciparum exhibits thioredoxin reductase activity. (1996) (54)
- Riboflavin Deficiency and Preeclampsia (2000) (54)
- Molecular cloning and characterization of a putative glutathione reductase gene, the PfGR2 gene, from Plasmodium falciparum. (1996) (54)
- The aza-analogues of 1,4-naphthoquinones are potent substrates and inhibitors of plasmodial thioredoxin and glutathione reductases and of human erythrocyte glutathione reductase. (2008) (53)
- Comparative structural analysis of oxidized and reduced thioredoxin from Drosophila melanogaster. (2005) (52)
- Characterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterparts (2005) (51)
- 1,3-Bis(2-chloroethyl)-1-nitrosourea as thiol-carbamoylating agent in biological systems. (1995) (51)
- Identification and Characterization of Novel Human Glucose-6-Phosphate Dehydrogenase Inhibitors (2013) (50)
- Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase: a unique bifunctional enzyme from Plasmodium falciparum. (2011) (50)
- Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents (2007) (50)
- Plasmoredoxin, a novel redox-active protein unique for malarial parasites. (2003) (49)
- Allosteric Coupling of Two Different Functional Active Sites in Monomeric Plasmodium falciparum Glyoxalase I* (2007) (49)
- In situ localization and structural analysis of the malaria pigment hemozoin. (2007) (49)
- Morphology-sensitive Raman modes of the malaria pigment hemozoin. (2009) (48)
- Antimalarial dual drugs based on potent inhibitors of glutathione reductase from Plasmodium falciparum. (2008) (48)
- Molecular basis of glutathione reductase deficiency in human blood cells. (2007) (47)
- Elucidation of Mycobacterium abscessus aminoglycoside and capreomycin resistance by targeted deletion of three putative resistance genes (2017) (47)
- Energy, Macronutrient Intake, and Anthropometrics of Vegetarian, Vegan, and Omnivorous Children (1–3 Years) in Germany (VeChi Diet Study) (2019) (47)
- Glyoxalase I of the malarial parasite Plasmodium falciparum: evidence for subunit fusion (2003) (47)
- Fiber array based hyperspectral Raman imaging for chemical selective analysis of malaria-infected red blood cells. (2015) (47)
- Real-Time Imaging of the Intracellular Glutathione Redox Potential in the Malaria Parasite Plasmodium falciparum (2013) (46)
- Synthesis and biological evaluation of 1,4-naphthoquinones and quinoline-5,8-diones as antimalarial and schistosomicidal agents. (2012) (46)
- 1,2,4‐Triazole‐3‐thione Compounds as Inhibitors of Dizinc Metallo‐β‐lactamases (2017) (44)
- Glutathione S-transferase from malarial parasites: structural and functional aspects. (2005) (43)
- Compounds Structurally Related to Ellagic Acid Show Improved Antiplasmodial Activity (2008) (43)
- Apicomplexan parasites: molecular approaches toward targeted drug development. (2011) (41)
- Molecular Genetics Evidence for the in Vivo Roles of the Two Major NADPH-dependent Disulfide Reductases in the Malaria Parasite* (2010) (41)
- Biochemical characterization of Toxoplasma gondii 1-Cys peroxiredoxin 2 with mechanistic similarities to typical 2-Cys Prx. (2005) (41)
- Plasmodium falciparum glutaredoxin-like proteins (2005) (41)
- Expression and regulation of thioredoxin reductases and other selenoproteins in bone. (2002) (40)
- Phospholipid Topography of Whole-Body Sections of the Anopheles stephensi Mosquito, Characterized by High-Resolution Atmospheric-Pressure Scanning Microprobe Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. (2015) (40)
- Truncated mutants of human thioredoxin reductase 1 do not exhibit glutathione reductase activity (2006) (39)
- Thioredoxin, thioredoxin reductase, and thioredoxin peroxidase of malaria parasite Plasmodium falciparum. (2002) (39)
- Plasmodium falciparum 2-Cys peroxiredoxin reacts with plasmoredoxin and peroxynitrite (2005) (38)
- Antiglioma activity of 2,2':6',2"-terpyridineplatinum(II) complexes in a rat model--effects on cellular redox metabolism. (2006) (38)
- The Subcellular Localization of Tubby-Like Proteins and Participation in Stress Signaling and Root Colonization by the Mutualist Piriformospora indica1[W] (2012) (38)
- Redox processes in malaria and other parasitic diseases (1994) (37)
- Synthesis of 5-nitro-2-furancarbohydrazides and their cis-diamminedichloroplatinum complexes as bitopic and irreversible human thioredoxin reductase inhibitors. (2005) (37)
- Mycobacterium tuberculosis lipoproteins in virulence and immunity – fighting with a double‐edged sword (2016) (37)
- The bacterial redox signaller pyocyanin as an antiplasmodial agent: comparisons with its thioanalog methylene blue (2011) (37)
- Denaturation and reactivation of dimeric human glutathione reductase--an assay for folding inhibitors. (1997) (36)
- Inherited Glutathione Reductase Deficiency and Plasmodium falciparum Malaria—A Case Study (2009) (35)
- Glucose‐6‐phosphate metabolism in Plasmodium falciparum (2012) (35)
- Discovery of a Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase inhibitor (R,Z)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-(2-fluorobenzylidene)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]thiazine-6-carboxamide (ML276) that reduces parasite growth in vitro. (2012) (35)
- Arylmethylamino steroids as antiparasitic agents (2017) (34)
- Resveratrol modulates mRNA transcripts of genes related to redox metabolism and cell proliferation in non-small-cell lung carcinoma cells (2007) (34)
- Flavin analogs with antimalarial activity as glutathione reductase inhibitors. (1990) (34)
- Plasmodium falciparum thioredoxins and glutaredoxins as central players in redox metabolism (2003) (33)
- Cynaropicrin targets the trypanothione redox system in Trypanosoma brucei. (2013) (32)
- SELDI‐TOF‐MS analysis of chloroquine resistant and sensitive Plasmodium falciparum strains (2007) (32)
- Peroxiredoxin systems of protozoal parasites. (2007) (32)
- A new animal model of femoral head necrosis induced by intraosseous injection of ethanol (2002) (31)
- High-Throughput Screening for Small-Molecule Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase 6-Phosphogluconolactonase (2012) (31)
- Antiparasitic peptides. (2013) (30)
- Of malaria, metabolism and membrane transport. (2004) (29)
- A high susceptibility to redox imbalance of the transmissible stages of Plasmodium falciparum revealed with a luciferase‐based mature gametocyte assay (2017) (29)
- Antiglioma activity of GoPI-sugar, a novel gold(I)-phosphole inhibitor: chemical synthesis, mechanistic studies, and effectiveness in vivo. (2014) (29)
- Crystal structure of the Plasmodium falciparum thioredoxin reductase-thioredoxin complex. (2013) (29)
- Redox regulation of Plasmodium falciparum ornithine δ-aminotransferase. (2010) (28)
- Effects of antioxidants on glutathione levels and clinical recovery from the malnutrition syndrome kwashiorkor – a pilot study (2005) (27)
- The redox systems of Plasmodium falciparum and Plasmodium vivax: comparison, in silico analyses and inhibitor studies. (2014) (27)
- Plasmodium falciparum glutathione reductase exhibits sequence similarities with the human host enzyme in the core structure but differs at the ligand-binding sites. (1995) (27)
- Biochemical and structural characterization of Plasmodium falciparum glutamate dehydrogenase 2. (2012) (26)
- Characterization of the 26S proteasome network in Plasmodium falciparum (2015) (26)
- Protein S-nitrosylation in Plasmodium falciparum. (2014) (25)
- News and views on thioredoxin reductases. (1999) (25)
- Antimalarial NADPH-Consuming Redox-Cyclers As Superior Glucose-6-Phosphate Dehydrogenase Deficiency Copycats (2015) (23)
- Determination of glutathione redox potential and pH value in subcellular compartments of malaria parasites (2017) (23)
- Molecular Mechanisms of Intrinsic Streptomycin Resistance in Mycobacterium abscessus (2017) (23)
- Lipoprotein Glycosylation by Protein-O-Mannosyltransferase (MAB_1122c) Contributes to Low Cell Envelope Permeability and Antibiotic Resistance of Mycobacterium abscessus (2017) (23)
- Glutathione mediated regulation of oligomeric structure and functional activity of Plasmodium falciparum glutathione S-transferase (2007) (23)
- Myristoylated adenylate kinase-2 of Plasmodium falciparum forms a heterodimer with myristoyltransferase. (2009) (22)
- High-resolution AP-SMALDI mass spectrometry imaging of Drosophila melanogaster (2017) (22)
- Hydrogen peroxide dynamics in subcellular compartments of malaria parasites using genetically encoded redox probes (2017) (22)
- Structural insights into the neuroprotective-acting carbonyl reductase Sniffer of Drosophila melanogaster. (2004) (21)
- H2O2 dynamics in the malaria parasite Plasmodium falciparum (2017) (21)
- 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors. (2020) (21)
- Microinjected glutathione reductase crystals as indicators of the redox status in living cells (1999) (21)
- Oxidative Stress and Antioxidant Defense in Malarial Parasites (2005) (21)
- Identification of M. tuberculosis thioredoxin reductase inhibitors based on high-throughput docking using constraints. (2013) (21)
- Alternative Protein Secretion in the Malaria Parasite Plasmodium falciparum (2015) (20)
- Plasmodium falciparum glucose‐6‐phosphate dehydrogenase 6‐phosphogluconolactonase is a potential drug target (2015) (20)
- Thiol-based posttranslational modifications in parasites. (2012) (20)
- Selenenyl iodide: a new substrate for mammalian thioredoxin reductase. (2003) (19)
- Protein-chemical standardization of the erythrocyte glutathione reductase activation test (EGRAC test). Application to hypothyroidism. (1991) (19)
- Depletion of Plasmodium berghei Plasmoredoxin Reveals a Non-Essential Role for Life Cycle Progression of the Malaria Parasite (2008) (19)
- Identification of Acid-Base Catalytic Residues of High-Mr Thioredoxin Reductase from Plasmodium falciparum* (2006) (19)
- Adenylate kinase and GTP:AMP phosphotransferase of the malarial parasite Plasmodium falciparum. Central players in cellular energy metabolism. (2004) (19)
- Interference with redox-active enzymes as a basis for the design of antimalarial drugs. (2006) (18)
- Synthesis of 5,5'-dithiobis(2-nitrobenzamides) as alternative substrates for trypanothione reductase and thioredoxin reductase: a microtiter colorimetric assay for inhibitor screening. (1999) (18)
- Biological activity and stability analyses of knipholone anthrone, a phenyl anthraquinone derivative isolated from Kniphofia foliosa Hochst. (2019) (18)
- Structural, functional and unfolding characteristics of glutathione S-transferase of Plasmodium vivax. (2009) (17)
- Detection of thiol-based redox switch processes in parasites – facts and future (2015) (17)
- Subcellular localization of adenylate kinases in Plasmodium falciparum (2012) (17)
- Differential genomic and proteomic profiling of glioblastoma cells exposed to terpyridineplatinum(II) complexes. (2009) (16)
- Structural and stability characteristics of a monothiol glutaredoxin: glutaredoxin-like protein 1 from Plasmodium falciparum. (2008) (16)
- A glutathione reductase-like flavoenzyme of the malaria parasite Plasmodium falciparum: structural considerations based on the DNA sequence. (1996) (16)
- Conformational stability and energetics of Plasmodium falciparum glutaredoxin. (2010) (15)
- Drug Discovery and Development for Schistosomiasis (2019) (15)
- Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif. (2021) (15)
- Insight into the selenoproteome of the malaria parasite Plasmodium falciparum. (2012) (15)
- Plasmodium Apicoplast Gln-tRNAGln Biosynthesis Utilizes a Unique GatAB Amidotransferase Essential for Erythrocytic Stage Parasites* (2015) (14)
- Atomic resolution crystal structure of glutaredoxin 1 from Plasmodium falciparum and comparison with other glutaredoxins. (2014) (13)
- Characterization of tryptophan aminotransferase 1 of Malassezia furfur, the key enzyme in the production of indolic compounds by M. furfur (2013) (13)
- Stable Integration and Comparison of hGrx1-roGFP2 and sfroGFP2 Redox Probes in the Malaria Parasite Plasmodium falciparum. (2018) (13)
- Epidemiologic, Phenotypic, and Structural Characterization of Aminoglycoside-Resistance Gene aac(3)-IV (2020) (13)
- Kinetic characterization of wild‐type and mutant human thioredoxin glutathione reductase defines its reaction and regulatory mechanisms (2018) (12)
- Galectin-8 binds to the Farnesylated C-terminus of K-Ras4B and Modifies Ras/ERK Signaling and Migration in Pancreatic and Lung Carcinoma Cells (2019) (12)
- Phosphoproteome Analysis of Cells Infected with Adapted and Nonadapted Influenza A Virus Reveals Novel Pro- and Antiviral Signaling Networks (2019) (12)
- NADPH-dependent disulphide reductases. (1989) (12)
- Redox Report Communications in Free Radical Research (2017) (12)
- Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically (2020) (12)
- 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity. (2021) (11)
- Comparison of methods probing the intracellular redox milieu in Plasmodium falciparum. (2016) (11)
- Synthesis and evaluation of 1,4–naphthoquinone ether derivatives as SmTGR inhibitors and new anti‐schistosomal drugs (2015) (11)
- Targeting the intersubunit cavity of Plasmodium falciparum glutathione reductase by a novel natural inhibitor: computational and experimental evidence. (2015) (11)
- Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase: characterization of the Plasmodium vivax enzyme and inhibitor studies (2019) (10)
- Assembly and functional expression of murine glutathione reductase cDNA: a sequence missing in expressed sequence tag libraries. (2000) (10)
- Flavins and flavoenzymes in diagnosis and therapy. (1999) (10)
- Characterization of Plasmodium falciparum 6-Phosphogluconate Dehydrogenase as an Antimalarial Drug Target. (2018) (9)
- Benzo[b]quinolizinium Derivatives Have a Strong Antimalarial Activity and Inhibit Indoleamine Dioxygenase (2015) (9)
- Efficacy of EBL-1003 (apramycin) against Acinetobacter baumannii lung infections in mice. (2020) (9)
- Large-scale differential proteome analysis in Plasmodium falciparum under drug treatment. (2015) (8)
- Characterization and redox regulation of Plasmodium falciparum methionine adenosyltransferase. (2016) (8)
- Flavins and flavoproteins: applications in medicine. (2014) (8)
- Photoinactivation of trypanothione reductase and glutathione reductase by Al-phthalocyanine tetrasulfonate and hematoporphyrin. (1996) (8)
- Highlight: Dynamics of Thiol-Based Redox Switches (2015) (8)
- Intake of micronutrients and fatty acids of vegetarian, vegan, and omnivorous children (1–3 years) in Germany (VeChi Diet Study) (2021) (8)
- Structural and Functional Characterization of Plasmodium falciparum Nicotinic Acid Mononucleotide Adenylyltransferase. (2016) (7)
- Redox status of patients before cardiac surgery (2017) (7)
- A Selective Inhibitor of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase (PfG6PDH) (2013) (7)
- A 2nd Selective Inhibitor of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase (PfG6PDH) - Probe 2 (2013) (7)
- Targeting spectrin redox switches to regulate the mechanoproperties of red blood cells (2020) (6)
- Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells. (2022) (6)
- Post-translational Modifications in Apicomplexan Parasites (2011) (6)
- Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis (2021) (6)
- Analyzing Thiol-Dependent Redox Networks in the Presence of Methylene Blue and Other Antimalarial Agents with RT-PCR-Supported in silico Modeling (2012) (6)
- The interactome of 2-Cys peroxiredoxins in Plasmodium falciparum (2019) (5)
- Technical Report Scintigraphic Evaluation of Bone Formation in Göttingen Minipigs (2010) (5)
- Monitoring yeast mitochondria with peroxiredoxin-based redox probes: the influence of oxygen and glucose availability (2017) (5)
- Two modes of catalysis have evolved (2000) (5)
- Report on a large animal study with Göttingen Minipigs where regenerates and controls for articular cartilage were created in a large number. Focus on the conditions of the operated stifle joints and suggestions for standardized procedures (2019) (4)
- Antimalarial activity of the ethanol/alcohol oxidase system in vitro. (1990) (4)
- Determination of Antiplasmodial Activity and Binding Affinity of Selected Natural Products towards PfTrxR and PfGR (2013) (3)
- Biochemical characterization of the recombinant schistosome tegumental protein SmALDH_312 produced in E. coli and baculovirus expression vector system (2021) (3)
- NMR assignments of oxidised thioredoxin from Plasmodium falciparum (2009) (3)
- Structure-Based Drug Development Against Malaria (2007) (3)
- Lipase Processing of Complex Lipid Antigens. (2016) (3)
- 1H, 13C, and 15N Sequence-specific Resonance Assignment and Secondary Structure of Plasmodium falciparum Thioredoxin (2005) (3)
- •EFFECT OF A RESORBABLE CaP COATING ON BONE-IMPLANT CONTACT AND DENSITY IN A GAP MODEL AFTER 4 AND 8 WEEKS. AN EXPERIMENTAL STUDY IN GÖTTINGER MINIPIGS. (2003) (2)
- Synthesis and Evaluation of Antimycobacterial and Antiplasmodial Activities of Hirsutellide A and Its Analogues (2020) (2)
- No evidence for inhibition of human glutathione reductase by valproic acid. (1994) (2)
- In-vitro safety and off-target profile of the anti-parasitic arylmethylaminosteroid 1o (2020) (2)
- Oxidative Stress in Infectious Diseases (2013) (1)
- Chemistry of polyhalogenated nitrobutadienes, 17: Efficient synthesis of persubstituted chloroquinolinyl-1H-pyrazoles and evaluation of their antimalarial, anti-SARS-CoV-2, antibacterial, and cytotoxic activities (2022) (1)
- Crystal structure of Leishmania donovani glucose 6-phosphate dehydrogenase reveals a unique N-terminal domain (2022) (1)
- Author Correction: Arylmethylamino steroids as antiparasitic agents (2019) (1)
- SOLUTION STRUCTURE OF AN HGR INHIBITOR, NMR, 10 STRUCTURES (1997) (1)
- Crystal structure of Plasmodium falciparum Glutathione reductase (2003) (1)
- Human Thioredoxin Reductases: Multifunctional Selenoproteines as Drug Targets (2004) (1)
- Energy metabolism as an antimalarial drug target. (2011) (1)
- 1795-1995: Milestones in ROS research. (1995) (1)
- The transcortical Göttingen Minipig model for testing osteointegration of implant surfaces and the influence of a soluble CaP coating on osteointegration (2006) (1)
- Identification of sulfenylation patterns in trophozoite stage Plasmodium falciparum using a non-dimedone based probe. (2021) (1)
- A novel small molecule that induces cytotoxicity in lung cancer cells inhibits disulfide reductases GSR and TXNRD1 (2021) (1)
- The immunomodulatory potential of the arylmethylaminosteroid sc1o (2020) (1)
- Dehydrogenases and Enzymes of the Mitochondrial Electron Transport Chain as Anti‐Apicomplexan Drug Targets (2011) (1)
- High‐throughput screening for Plasmodium falciparum glucose‐6‐phosphate dehydrogenase‐6‐phosphogluconolactonase inhibitors (2012) (0)
- HUMAN GLUTATHIONE REDUCTASE MODIFIED BY DINITROSOGLUTATHIONE (1998) (0)
- [Figure], 1H NMR Spectrum of ML304 (500 MHz, CDCl3) (2013) (0)
- Figure 4, Profile of ML304 against the Psychoactive Drug Screening Program (PDSP) % inhibition at 10 μM (2013) (0)
- Glucose 6-phosphate dehydrogenase 6-phosphogluconolactonase: characterization of the Plasmodium vivax enzyme and inhibitor studies (2019) (0)
- Carbonyl reductase Sniffer of D. melanogaster (2004) (0)
- Russian Redox Meeting (2016) (0)
- Scheme 1, Synthesis of ML276 (2013) (0)
- Crystal structure of the human thioredoxin reductase – thioredoxin complex implicates movement of the C-terminal redox center by 20 Å upon catalysis (2011) (0)
- BINDING OF FAD TO BCNU-TREATED APOGLUTATHIONE REDUCTASE (1991) (0)
- Crystal Structure Analysis of the human Glutahione Reductase, complexed with GoPI (2006) (0)
- Table 3, Probe and Analog Submissions to MLSMR (Evotec) for P. falciparum G-6PDH antagonists (2013) (0)
- Is methylene blue a prodrug of azure b (2013) (0)
- Expanding the Scope of the T7 RNA Polymerase - A Novel Plasmid Requires T7 Rna Polymerase for Replication (2017) (0)
- Drosophila thioredoxin, oxidized, P21 (2004) (0)
- Studies on ligand binding and enzyme inhibition of Plasmodium falciparum glutathione S-transferase (2006) (0)
- Figure 1, Structure of ML304 (2013) (0)
- Prominent role of cysteine residues C49 and C343 in regulating Plasmodiumfalciparum pyruvate kinase activity. (2022) (0)
- Molecular principles of parasitism. Preface. (2012) (0)
- Crystal structure of plasmoredoxin, a redox-active protein unique for malaria parasites (2022) (0)
- Current Aspects of Endoperoxides in Antiparasitic Chemotherapy (2011) (0)
- Plasmodium falciparum 6-phosphogluconate dehydrogenase in its apo form, in complex with its cofactor NADP+ and in complex with its substrate 6-phosphogluconate (2018) (0)
- Table 1, Biological activity summary & AIDs for probe (2013) (0)
- Derivatives of Steroidbenzylaminen with antiparasitic, antibacterial, antifungal and / or antiviral action (2010) (0)
- Figure 4, PDSP Panel for ML276 - CID 53362052 (2013) (0)
- Identification and characterisation of the tegument-expressed aldehyde dehydrogenase SmALDH_312 of Schistosoma mansoni, a target of disulfiram. (2023) (0)
- The glutathione redox couple as a thiol switch operator in the malaria parasite Plasmodium falciparum (2014) (0)
- Drosophila thioredoxin, reduced, P6522 (2004) (0)
- Figure 2, Investigation of chemical reactivity/stability of ML276 via GSH adduct formation (2013) (0)
- Structure of Plasmodium falciparum ornithine delta-aminotransferase (2010) (0)
- Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically (2022) (0)
- Trypanosoma brucei tranferrin receptor mRNA contains iron elements in the 5'-UTR (2002) (0)
- Structure of Plasmodium falciparum thioredoxin reductase-thioredoxin complex (2013) (0)
- Plasmodium falciparum nicotinic acid mononucleotide adenylyltransferase complexed with NaAD (2016) (0)
- Trypanosoma brucei transferrin receptor mRNA contains iron-responsive elements in the 5'-UTR (2004) (0)
- Drospohila thioredoxin, oxidized, P41212 (2004) (0)
- Mass spectrometic analysis of human glutathione reductase modified by a gold-phosphole inhibitor (2005) (0)
- Human thioredoxin reductase − structural and mechanistic characteristics of an anticancer drug target (2008) (0)
- HUMAN GLUTATHIONE REDUCTASE MODIFIED BY DIGLUTATHIONE-DINITROSO-IRON (1998) (0)
- Structural and functional analysis of lipoprotein glycosylation in fast- and slow-growing mycobacteria (2018) (0)
- Table 4, Summary of in vitro ADME Properties of P. falciparum G6PDH inhibitor probe ML276 (2013) (0)
- Nutrient intake and anthropometrics of vegetarian, vegan and omnivorous children (1–3 y) in Germany (2020) (0)
- Challenges and Pitfalls of Experimental Bariatric Procedures in Rats (2012) (0)
- Response of the Committee for Anaesthesia, Analgesia and Pain Prophylaxis of the Society for Laboratory Animal Science to ‘Temporary inhalation anaesthesia in experimental pigs’ (2011) (0)
- Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs (2023) (0)
- The selenoproteome of the malarial parasite Plasmodium falciparum as potential drug target (2006) (0)
- THE EGRAC AS A MEASURE OF THE RIBOFLAVIN STATUS IN MAN. TITRATION OF HEMOLYS ATE FAD WITH APOGLUTATHIONE REDUCTASE (1991) (0)
- Figure 3, Specificity of ML276 Inhibition for the Plasmodium vs. human G6PDH enzyme activity (2013) (0)
- Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy (2009) (0)
- Human Glutathione Reductase Inactivated by Peroxynitrite (2002) (0)
- Crystal Structure of Plasmodium falciparum antioxidant protein (1-Cys peroxiredoxin) (2005) (0)
- Excited electronic states of flavin-containing coenzyme models (1988) (0)
- [Figure], 13C NMR Spectrum of ML276 (500 MHz, acetic acid-d4) (2013) (0)
- Dynamics of thiol-based redox switches: redox at its peak! (2021) (0)
- Arylmethylamino steroids as novel antiparasitic agents (2017) (0)
- Resveratrol modulates the mRNA levels of genes related to redox metabolism and apoptosis in non-small cell lung cancer cells (2006) (0)
- Scheme 1, Synthesis of ML304 (2013) (0)
- [Figure], 13C NMR Spectrum of ML304 (125 MHz, CDCl3) (2013) (0)
- X-ray structure of human thioredoxin reductase 1 (2007) (0)
- Drospohila thioredoxin, oxidized, P42212 (2004) (0)
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