Katrin Rittinger
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Katrin Rittingerphilosophy Degrees
Philosophy
#11705
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#16169
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Logic
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#10656
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Katrin Rittingerbiology Degrees
Biology
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#16917
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Molecular Biology
#2482
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#2521
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Biochemistry
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#2894
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Philosophy Biology
Katrin Rittinger's Degrees
- PhD Biochemistry University of Oxford
Why Is Katrin Rittinger Influential?
(Suggest an Edit or Addition)According to Wikipedia, Katrin Rittinger is a professor in structural biology who has made significant contributions to the ubiquitination field. She is a senior scientist at the Francis Crick Institute and was awarded European Molecular Biology Organization membership in 2019. Rittinger is on the Editorial Board of Biochemical Journal and has written on transparency and openness in science.
Katrin Rittinger's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- The Structural Basis for 14-3-3:Phosphopeptide Binding Specificity (1997) (1575)
- SHARPIN forms a linear ubiquitin ligase complex regulating NF-κB activity and apoptosis (2011) (676)
- Activation and assembly of the NADPH oxidase: a structural perspective. (2005) (540)
- Structural analysis of 14-3-3 phosphopeptide complexes identifies a dual role for the nuclear export signal of 14-3-3 in ligand binding. (1999) (503)
- Structure at 1.65 Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue (1997) (420)
- Molecular Basis of Phosphorylation-Induced Activation of the NADPH Oxidase (2003) (383)
- Structure of the TPR domain of p67phox in complex with Rac.GTP. (2000) (307)
- The structural basis of Arfaptin-mediated cross-talk between Rac and Arf signalling pathways (2001) (258)
- Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAP (1997) (256)
- LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes (2015) (216)
- LUBAC synthesizes linear ubiquitin chains via a thioester intermediate (2012) (211)
- Human immunodeficiency virus reverse transcriptase substrate-induced conformational changes and the mechanism of inhibition by nonnucleoside inhibitors. (1995) (174)
- Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP (2013) (172)
- Functional role of TRIM E3 ligase oligomerization and regulation of catalytic activity (2016) (133)
- Architecture of the p40-p47-p67 phox Complex in the Resting State of the NADPH Oxidase (2002) (122)
- Structural determinants of TRIM protein function. (2017) (119)
- SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes (2016) (113)
- Control of Mitotic Exit in Budding Yeast (2002) (111)
- Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition (2018) (104)
- MgF(3)(-) as a transition state analog of phosphoryl transfer. (2002) (98)
- Linear ubiquitin chains: enzymes, mechanisms and biology (2017) (84)
- RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns (2018) (82)
- Function of the Nucleotide Exchange Activity of Vav1 in T Cell Development and Activation (2009) (79)
- Fragment-Based Covalent Ligand Screening Enables Rapid Discovery of Inhibitors for the RBR E3 Ubiquitin Ligase HOIP (2019) (75)
- Molecular insights into RBR E3 ligase ubiquitin transfer mechanisms (2016) (71)
- Crucial structural role for the PH and C1 domains of the Vav1 exchange factor (2008) (70)
- Cbl promotes clustering of endocytic adaptor proteins (2005) (66)
- Dimerization kinetics of HIV-1 and HIV-2 reverse transcriptase: a two step process. (1995) (64)
- NEMO oligomerization and its ubiquitin-binding properties (2009) (58)
- Structures of dimeric GIT1 and trimeric beta-PIX and implications for GIT-PIX complex assembly. (2009) (56)
- Solution NMR investigation of the CD95/FADD homotypic death domain complex suggests lack of engagement of the CD95 C terminus. (2010) (54)
- Structure and Sites of Phosphorylation of 14-3-3 Protein: Role in Coordinating Signal Transduction Pathways (1997) (53)
- Regulation of NOXO1 Activity through Reversible Interactions with p22phox and NOXA1 (2010) (52)
- Sequestering of Rac by the Yersinia Effector YopO Blocks Fcγ Receptor-mediated Phagocytosis* (2009) (42)
- Structural Studies of HHARI/UbcH7∼Ub Reveal Unique E2∼Ub Conformational Restriction by RBR RING1 (2017) (42)
- Preparation of GTPases for structural and biophysical analysis. (2002) (42)
- The Tandem CARDs of NOD2: Intramolecular Interactions and Recognition of RIP2 (2012) (39)
- Structural basis for the glycosyltransferase activity of the Salmonella effector SseK3 (2018) (39)
- Kinetics of interaction of HIV reverse transcriptase with primer/template. (1993) (38)
- Conformational stability of dimeric HIV-1 and HIV-2 reverse transcriptases. (1995) (32)
- Support for shared ancestry of GAPs (1998) (30)
- Structural Analysis of SHARPIN, a Subunit of a Large Multi-protein E3 Ubiquitin Ligase, Reveals a Novel Dimerization Function for the Pleckstrin Homology Superfold* (2012) (30)
- Mechanism and function of Vav1 localisation in TCR signalling (2012) (29)
- Linear ubiquitination by LUBEL has a role in Drosophila heat stress response (2016) (29)
- Interface Peptides as Structure-based Human Immunodeficiency Virus Reverse Transcriptase Inhibitors (*) (1995) (26)
- Interactions between Cdc42 and the scaffold protein Scd2: requirement of SH3 domains for GTPase binding. (2005) (25)
- Determination of the pKa of the N-terminal amino group of ubiquitin by NMR (2017) (24)
- Characterisation of class VI TRIM RING domains: linking RING activity to C-terminal domain identity (2019) (21)
- In silico phosphorylation of the autoinhibited form of p47(phox): insights into the mechanism of activation. (2010) (20)
- Structure–function analyses of the bacterial zinc metalloprotease effector protein GtgA uncover key residues required for deactivating NF-κB (2018) (20)
- Isoform-selective interaction of the adaptor protein Tks5/FISH with Sos1 and dynamins. (2009) (19)
- Interaction between NOD2 and CARD9 involves the NOD2 NACHT and the linker region between the NOD2 CARDs and NACHT domain (2014) (18)
- Determinants of E2-ubiquitin conjugate recognition by RBR E3 ligases (2018) (16)
- The parkin-coregulated gene product PACRG promotes TNF signaling by stabilizing LUBAC (2020) (14)
- Escherichia coli isocitrate dehydrogenase kinase/phosphatase. Overproduction and kinetics of interaction with its substrates by using intrinsic fluorescence and fluorescent nucleotide analogues. (1996) (14)
- The Biophysical Characterisation and SAXS Analysis of Human NLRP1 Uncover a New Level of Complexity of NLR Proteins (2016) (12)
- Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases (2019) (12)
- Does it take two to tango? RING domain self-association and activity in TRIM E3 ubiquitin ligases (2020) (12)
- Snapshots Form a Big Picture of Guanine Nucleotide Exchange (2009) (10)
- Sedimentation equilibrium studies. (2004) (8)
- Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome (2022) (7)
- Characterization of fluorescence-labeled DNA by time-resolved fluorescence spectroscopy (1991) (6)
- pUBLically unzipping Parkin: how phosphorylation exposes a ligase bit by bit (2015) (5)
- Purification and characterization of guanine nucleotide dissociation stimulator protein. (2000) (5)
- RNA binding regulates TRIM25-mediated RIG-I ubiquitylation (2020) (5)
- Transparency and openness in science (2017) (4)
- Crystallization of SHARPIN using an automated two-dimensional grid screen for optimization (2012) (3)
- Structure of the Rac/p67phox complex (2000) (3)
- Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition (2018) (3)
- Reply to “The binding stoichiometry of CIN85 SH3 domain A and Cbl-b” (2008) (3)
- Faculty Opinions recommendation of Ubiquitin, SUMO, and NEDD8: key targets of bacterial pathogens. (2018) (3)
- Targeting the ubiquitin system by fragment-based drug discovery (2022) (2)
- Synthesis of 2′,3′,5′-trideoxyuridine-5′-methylphosphonic Acid and its Diphosphate Derivative. Study of the Interaction with HIV-1 reverse Transcriptase (1994) (2)
- Structural basis for ubiquitylation by HOIL-1 (2022) (1)
- Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments. (2023) (1)
- In Vitro Analysis of Tem1 GTPase Activity and Regulation by the Bfa1/Bub2 GAP. (2017) (1)
- Mechanistic insights into RNA binding and RNA-regulated RIG-I ubiquitination by TRIM25 (2020) (1)
- Complex of influenza A NS1 with TRIM25 coiled coil domain (2018) (0)
- Crystal structure and function of 14-3-3 proteins: Role in coordinating signal transduction pathways (1997) (0)
- COMPLEX BETWEEN CDC42HS.GMPPNP AND P50 RHOGAP (H. SAPIENS) (1998) (0)
- Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity (2022) (0)
- Synthese of 2',3',5'−trideoxyuridine−5'−methylphosphonic acid and its diphosphate derivative. Study of interaction with HIV−1 Reverse Transcriptase (1994) (0)
- dAb3/HOIP-RBR apo structure (2019) (0)
- Crystal structure of the PH domain of SHARPIN (2012) (0)
- Crystal structure of Salmonella zinc metalloprotease effector GtgA in complex with p65 (2018) (0)
- dAb3/HOIP-RBR-HOIPIN-8 (2019) (0)
- Complex of influenza A NS1 effector domain with TRIM25 coiled coil (2018) (0)
- RHO/RHOGAP/GDP(DOT)ALF4 COMPLEX (1998) (0)
- Advanced rules of relays (2020) (0)
- Crystal Structure of the Trimeric beta-PIX Coiled-Coil Domain (2009) (0)
- Crystal Structure of RhoA.GDP.MgF3-in Complex with RhoGAP (2003) (0)
- Determinants of E2-ubiquitin conjugate recognition by RBR E3 ligases (2018) (0)
- Structure of autoinhibited p47phox (2003) (0)
- Crystal structure of the Salmonella effector SseK3 in complex with UDP-GlcNAc and Manganese (2018) (0)
- Editorial overview: Multi-protein assemblies in signaling. (2014) (0)
- 14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 2) (1999) (0)
- Crystal structure of the catalytic core of E3 ligase HOIP (2013) (0)
- X-ray Structure of the Dimeric GIT1 Coiled-Coil Domain (2009) (0)
- Sedimentation equilibrium studies. (2015) (0)
- A chemoproteomic platform for reactive fragment profiling against the deubiquitinases (2023) (0)
- beta PIX-SH3 complexed with a Cbl-b peptide (2005) (0)
- Structure of the p22phox-p47phox complex (2003) (0)
- 14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (1999) (0)
- dAb3/HOIP-RBR-Ligand3 (2019) (0)
- Solution structure of TRIM28 RING domain (2019) (0)
- Characterisation of HOIP RBR E3 ligase conformational dynamics using integrative modelling (2022) (0)
- dAb3/HOIP-RBR-Ligand2 (2019) (0)
- Complex of TRIM25 RING with UbcH5-Ub (2016) (0)
- Crystal structure of Salmonella zinc metalloprotease effector GtgA (2018) (0)
- Faculty of 1000 evaluation for Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control. (2018) (0)
- Structure of an active ligase (HOIP-H889A)/ubiquitin transfer complex (2013) (0)
- Linear ubiquitination by LUBEL plays a critical role in Drosophila heat stress response (2016) (0)
- RBR ligase–mediated ubiquitin transfer: a tale with many twists and turns (2018) (0)
- Ubiquitin-dependent regulation of immune and inflammatory signaling pathways (2014) (0)
- 14-3-3 ZETA/PHOSPHOPEPTIDE COMPLEX (MODE 1) (1999) (0)
- dAb3/HOIP-RBR-Ligand4 (2019) (0)
- Crystal structure of the salmonella effector SseK3 (2018) (0)
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