Katrina Mealey
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American veterinary pharmacologist
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Katrina Mealey's Degrees
- PhD Pharmacology Washington State University
Why Is Katrina Mealey Influential?
(Suggest an Edit or Addition)According to Wikipedia, Katrina Ann Mealey is an American veterinary pharmacologist. She is a Regents Professor and Richard L. Ott Endowed Chair in Small Animal Medicine and Research at Washington State University. Early life and education Mealey was born and raised in New Mexico to parents Maria Gonzales and Wayne R. Larson. She completed her Bachelor of Science degree at the University of New Mexico before marrying her husband, Robert Mealey, and enrolling together at Colorado State University for their DVM. Following her DVM, Mealey completed two internships and a residency before completing her PhD at Texas A&M University in 1998.
Katrina Mealey's Published Works
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Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene. (2001) (408)
- Breed distribution and history of canine mdr1-1Delta, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage. (2004) (189)
- The genomic architecture of segmental duplications and associated copy number variants in dogs. (2008) (156)
- Therapeutic implications of the MDR-1 gene. (2004) (148)
- Clinical pharmacology and therapeutics. (2013) (94)
- Breed distribution of the ABCB1-1Delta (multidrug sensitivity) polymorphism among dogs undergoing ABCB1 genotyping. (2008) (90)
- Pharmacogenetic and Metabolic Differences Between Dog Breeds: Their Impact on Canine Medicine and the Use of the Dog as a Preclinical Animal Model (2008) (89)
- Increased toxicity of P-glycoprotein-substrate chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin sensitivity. (2003) (87)
- Loperamide toxicity in a collie with the MDR1 mutation associated with ivermectin sensitivity. (2004) (77)
- Frequency of the mutant MDR1 allele associated with ivermectin sensitivity in a sample population of collies from the northwestern United States. (2002) (68)
- The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs. (2005) (65)
- The pharmacogenomics of P-glycoprotein and its role in veterinary medicine. (2008) (59)
- Systemic absorption of amitriptyline and buspirone after oral and transdermal administration to healthy cats. (2004) (58)
- Doxycycline Induces Expression of P Glycoprotein in MCF-7 Breast Carcinoma Cells (2002) (56)
- Frequency of the mutant MDR1 allele associated with multidrug sensitivity in a sample of collies from France. (2004) (55)
- Frequency of the mutant MDR1 allele associated with multidrug sensitivity in a sample of herding breed dogs living in Australia. (2005) (54)
- P‐Glycoprotein Mediated Drug Interactions in Animals and Humans with Cancer (2015) (54)
- Pharmacokinetics of flunixin meglumine in donkeys, mules, and horses. (1999) (54)
- Ivermectin toxicity in an Australian Shepherd dog with the MDR1 mutation associated with ivermectin sensitivity in Collies. (2003) (54)
- Comparative pharmacokinetics of meloxicam in clinically normal horses and donkeys. (2006) (50)
- ABCG2 transporter: therapeutic and physiologic implications in veterinary species. (2012) (49)
- Challenges in exploring the cytochrome P450 system as a source of variation in canine drug pharmacokinetics (2013) (49)
- Molecular genetic basis for fluoroquinolone-induced retinal degeneration in cats (2011) (48)
- Pharmacokinetics of gallium maltolate after intragastric administration in neonatal foals. (2007) (46)
- The genomic architecture of segmental duplications and copy number variants in dogs (2009) (46)
- Doxorubicin induced expression of P-glycoprotein in a canine osteosarcoma cell line. (1998) (46)
- Canine ABCB1 and macrocyclic lactones: heartworm prevention and pharmacogenetics. (2008) (46)
- Tramadol Metabolism to O-Desmethyl Tramadol (M1) and N-Desmethyl Tramadol (M2) by Dog Liver Microsomes: Species Comparison and Identification of Responsible Canine Cytochrome P450s (2016) (45)
- ABCB1-1Delta polymorphism can predict hematologic toxicity in dogs treated with vincristine. (2008) (44)
- Pharmacokinetics and cardiopulmonary effects of guaifenesin in donkeys. (1997) (43)
- Comparative pharmacokinetics of phenylbutazone and its metabolite oxyphenbutazone in clinically normal horses and donkeys. (1997) (42)
- P-Glycoprotein Contributes to the Blood-Brain, but Not Blood-Cerebrospinal Fluid, Barrier in a Spontaneous Canine P-Glycoprotein Knockout Model (2008) (41)
- An insertion mutation in ABCB4 is associated with gallbladder mucocele formation in dogs (2010) (34)
- Hypercalcemia associated with granulomatous disease in a cat. (1999) (31)
- Biliary excretion of technetium-99m-sestamibi in wild-type dogs and in dogs with intrinsic (ABCB1-1Delta mutation) and extrinsic (ketoconazole treated) P-glycoprotein deficiency. (2009) (30)
- Assessment of antiepileptic drugs as substrates for canine P-glycoprotein. (2007) (30)
- Digoxin and mexiletine sensitivity in a Collie with the MDR1 mutation. (2006) (29)
- Survival time, lifespan, and quality of life in dogs with idiopathic Fanconi syndrome. (2004) (28)
- Pharmacokinetics of phenylbutazone and its metabolite oxyphenbutazone in miniature donkeys. (2001) (28)
- Oral bioavailability of P-glycoprotein substrate drugs do not differ between ABCB1-1Δ and ABCB1 wild type dogs. (2010) (27)
- Transdermal absorption of a liposome-encapsulated formulation of lidocaine following topical administration in cats. (2002) (27)
- Pharmacokinetics of sulfamethoxazole and trimethoprim in donkeys, mules, and horses. (2002) (27)
- Effect of low doses of cosyntropin on serum cortisol concentrations in clinically normal dogs. (2007) (25)
- Intravenous fat emulsion as treatment for ivermectin toxicosis in three dogs homozygous for the ABCB1-1Δ gene mutation. (2011) (25)
- ABCB1-1 Delta (MDR1-1 Delta) genotype is associated with adverse reactions in dogs treated with milbemycin oxime for generalized demodicosis. (2009) (24)
- Comparative pharmacokinetics of caffeine and three metabolites in clinically normal horses and donkeys. (1997) (24)
- Pharmacokinetics of R(-) and S(+) carprofen after administration of racemic carprofen in donkeys and horses. (2004) (23)
- Differential expression of CYP3A12 and CYP3A26 mRNAs in canine liver and intestine. (2008) (23)
- Dexamethasone treatment of a canine, but not human, tumour cell line increases chemoresistance independent of P-glycoprotein and multidrug resistance-related protein expression. (2003) (22)
- Population variability in animal health: Influence on dose-exposure-response relationships: Part I: Drug metabolism and transporter systems. (2018) (22)
- Frequency of the mutant MDR1 allele in dogs in the UK (2012) (21)
- Comparison of the hypothalamic^pituitary^adrenal axis in MDR1-1D and MDR1 wildtype dogs (2007) (21)
- Systemic Mycobacterium avium infection in a dog diagnosed by polymerase chain reaction analysis of buffy coat. (2005) (20)
- Association between ABCB1 genotype and seizure outcome in Collies with epilepsy. (2012) (19)
- Adverse drug reactions in veterinary patients associated with drug transporters. (2013) (19)
- Comparative metabolism of mycophenolic acid by glucuronic acid and glucose conjugation in human, dog, and cat liver microsomes (2017) (18)
- Vincristine-induced central neurotoxicity in a collie homozygous for the ABCB1Δ mutation. (2012) (18)
- Personalized medicine: going to the dogs? (2019) (18)
- Identification of a nonsense mutation in feline ABCB1. (2015) (17)
- Bioavailability of benzodiazepines following rectal administration of diazepam in dogs. (1995) (17)
- Adverse Drug Reactions in Herding-Breed Dogs: The Role of P-Glycoprotein * (2006) (17)
- Identification of canine cytochrome P‐450s (CYPs) metabolizing the tramadol (+)‐M1 and (+)‐M2 metabolites to the tramadol (+)‐M5 metabolite in dog liver microsomes (2018) (16)
- Pharmacokinetics of gentamicin in donkeys. (1996) (15)
- Pharmacokinetics of imipramine in narcoleptic horses. (2001) (15)
- Fecal polymerase chain reaction with 16S ribosomal RNA primers can detect the presence of gastrointestinal Helicobacter in dogs. (2002) (15)
- Ivermectin: Macrolide Antiparasitic Agents (2006) (14)
- Nephrotoxicosis associated with topical administration of gentamicin in a cat. (1994) (14)
- Oral Coadministration of Fluconazole with Tramadol Markedly Increases Plasma and Urine Concentrations of Tramadol and the O-Desmethyltramadol Metabolite in Healthy Dogs (2018) (14)
- Pharmacokinetics of gentamicin in Mammoth asses. (1994) (14)
- The Effect of the Canine ABCB1‐1Δ Mutation on Sedation after Intravenous Administration of Acepromazine (2016) (13)
- Normal dogs treated with famotidine for 14 days have only transient increases in serum gastrin concentrations. (2011) (12)
- Establishment of a cell line for assessing drugs as canine P‐glycoprotein substrates: proof of principle (2017) (12)
- Functional cystic thyroid adenoma in a cat. (2001) (12)
- Lack of association of ABCB4 insertion mutation with gallbladder mucoceles in dogs (2014) (11)
- Penicillins and β-lactamase inhibitor combinations (2001) (11)
- Immunosuppressant inhibition of P-glycoprotein function is independent of drug-induced suppression of peptide-prolyl isomerase and calcineurin activity (1999) (11)
- Gallium Therapy: A Novel Metal-Based Antimicrobial Strategy for Potential Control of Rhodococcus equi Foal Pneumonia (2006) (9)
- Identification of DNA variants in the canine beta-1 adrenergic receptor gene. (2013) (9)
- Pharmacokinetics, effects on renal function, and potentiation of atracurium-induced neuromuscular blockade after administration of a high dose of gentamicin in isoflurane-anesthetized dogs. (1996) (9)
- Impact of the canine double-deletion &bgr;1 adrenoreceptor polymorphisms on protein structure and heart rate response to atenolol, a &bgr;1-selective &bgr;-blocker (2015) (8)
- Determination of optimal storage temperature and duration for analysis of total and isoenzyme lactate dehydrogenase activities in canine serum and cerebrospinal fluid. (2015) (8)
- Differential expression of CYP3A12 and CYP3A26 mRNAs in canine liver and intestine (2008) (8)
- Synovial T-cell lymphoma of the stifle in a dog. (2002) (8)
- Evaluation of the flanking nucleotide sequences of sarcomeric hypertrophic cardiomyopathy substitution mutations. (2008) (7)
- Role of an ABCB11930_1931del TC gene mutation in a temporal cluster of macrocyclic lactone-induced neurologic toxicosis in cats associated with products labeled for companion animal use. (2021) (7)
- Pharmacotherapeutics for Veterinary Dispensing (2019) (7)
- Innovation, entrepreneurship, promotion, and tenure. (2021) (6)
- Comparison of plasma disposition of alkaloids after lupine challenge in cattle that had given birth to calves with lupine-induced arthrogryposis or clinically normal calves. (2004) (6)
- Evaluation of vincristine-associated myelosuppression in Border Collies. (2013) (5)
- Polymorphisms in the canine glucocorticoid receptor alpha gene (NR3C1α). (2016) (5)
- Pharmacokinetics and haematological effects of a single intravenous dose of mitoxantrone in cats. (1995) (5)
- Adverse reaction to apomorphine in a Collie homozygous for the ABCB1-1∆ (MDR1) mutation. (2017) (5)
- Sequence and structural analysis of the presumed downstream promoter of the canine mdr1 gene. (2003) (4)
- Canine ABCB4: Tissue expression and cDNA structure. (2010) (4)
- Excessive Cyclosporine-Associated Immunosuppression in a Dog Heterozygous for the MDR1 (ABCB1-1Δ) Mutation. (2020) (4)
- Comparison of chemotherapeutic drug resistance in cells transfected with canine ABCG2 or feline ABCG2† (2017) (4)
- Evaluation of Transdermal Administration of Phenobarbital in Healthy Cats. (2019) (4)
- Neuromuscular effects of doxacurium chloride in isoflurane-anesthetized dogs. (1998) (4)
- Evaluation of the biliary and brain distribution of technetium Tc 99m sestamibi in healthy dogs with the ABCB1 wildtype genotype before and after treatment with spinosad. (2012) (4)
- Development of prednisone resistance in naïve canine lymphoma: Longitudinal evaluation of NR3C1α, ABCB1, and 11β-HSD mRNA expression. (2020) (2)
- Penicillins and beta-lactamase inhibitor combinations. (2001) (2)
- Canine Albumin Polymorphisms and Their Impact on Drug Plasma Protein Binding (2019) (2)
- Comparative Pharmacokinetics and Pharmacodynamics (2019) (2)
- Lupine-induced crooked calf diseases: plasma disposition of lupine alkaloids following repeated challenge in cattle that have given birth to affected calves or those that have borne normal calves. (2007) (2)
- Breed Differences and Pharmacogenetics (2019) (2)
- Tyrosine Kinase Inhibitors Enhance Ciprofloxacin-Induced Phototoxicity by Inhibiting ABCG2 (2014) (2)
- Relationship between the melanocortin-1 receptor (MC1R) variant R306ter and physiological responses to mechanical or thermal stimuli in Labrador Retriever dogs. (2017) (1)
- WHAT YOU DON ’ T KNOW ABOUT P-GLYCOPROTEIN CAN HURT YOU (2013) (1)
- Canine and feline P‐glycoprotein deficiency: What we know and where we need to go (2022) (1)
- PREVALENCE OF THE ABCB1-1Δ GENE IN NONDOMESTIC SPECIES OF THE CANIDAE FAMILY (2021) (1)
- Canine orosomucoid (alpha-1 acid glycoprotein) variants and their influence on drug plasma protein binding. (2020) (1)
- copy number variants in dogs The genomic architecture of segmental duplications and associated Material (2009) (1)
- Tolerance and Pharmacokinetics of Galliprant™ Administered Orally to Collies Homozygous for MDR1‐1Δ (2021) (1)
- Contents. (2003) (0)
- Contents Vol. 87, 2014 (2014) (0)
- Appendix I: Zoonotic Diseases of Dogs, Cats, and Horses (2019) (0)
- SA251 WHAT YOU DON’T KNOW ABOUT P-GLYCOPROTEIN CAN HURT YOU (& YOUR PATIENTS!) (2013) (0)
- Appendix B: Directional Anatomical Terminology of Bipeds Quadrupeds (2019) (0)
- Oral co-administration of fluconazole with tramadol markedly increases plasma and urine concentrations of tramadol and the O-desmethyltramadol metabolite (M1) in healthy dogs (2018) (0)
- Counseling for Owners of Veterinary Patients (2019) (0)
- Alternative Dosing Strategies for Cats (2008) (0)
- Appendix A: Veterinary Teaching Hospital Pharmacy Contact Information (2019) (0)
- Questions reported risks of Salmonella infections. (2002) (0)
- Appendix F: Veterinary Pharmacogenetics Testing Laboratories with Counseling Expertise (2019) (0)
- Researchmutation in ABCB4 is associated with gallbladder mucocele formation in dogs (2010) (0)
- Human Over‐the‐Counter (OTC) Products (2019) (0)
- Assessment of verdinexor as a canine P-glycoprotein substrate. (2023) (0)
- Personalized medicine: going to the dogs? (2019) (0)
- Variation in Theileria equi drug susceptibility in vitro and the potential role of ABC transporters as mediators of parasitic drug resistance (2012) (0)
- Special Considerations for Service, Working, and Performance Animals (2019) (0)
- Ophthalmic Pharmacotherapeutics (2019) (0)
- In vitro identification of canine cytochrome P-450 (CYP) enzymes that metabolize the (+)-M1 tramadol metabolite to the (+)-M5 metabolite (2017) (0)
- Chapter 52 – Ivermectin: Macrolide Antiparasitic Agents (2013) (0)
- ResearchAn insertion mutation in ABCB 4 is associated with gallbladder mucocele formation in dogs (2015) (0)
- Respiratory Pharmacotherapeutics (2019) (0)
- Appendix G: Therapeutic Drug Monitoring Laboratories (2019) (0)
- Endocrine Pharmacotherapeutics (2019) (0)
- Sarcoloidosis: A Rare Case of Co-Existent Systemic Sarcoidosis and Amyloidosis (2019) (0)
- Appendix C: Vital signs and potential monitoring parameters for dogs, cats, horses, and ferrets (2019) (0)
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