Kazuaki Takabe

Q: What Schools Are Affiliated With Kazuaki Takabe

Kazuaki Takabe is affiliated with the following schools: Hokkaido University, University at Buffalo, Niigata University, University of Tokyo, Fukushima Medical University, University of Florida, Virginia Commonwealth University, Baylor College of Medicine, Yokohama City University, Osaka University, Tokyo Medical University, Kyoto University

Kazuaki Takabe's AcademicInfluence.com Rankings

Kazuaki Takabe

Physics

#6609

World Rank

#8573

Historical Rank

physics Degrees

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Physics

Kazuaki Takabe's Degrees

PhD Physics University of Tokyo
Masters Physics University of Tokyo
Bachelors Physics University of Tokyo

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Kazuaki Takabe's Published Works

Number of citations in a given year to any of this author's works

Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author

Published Works

“Inside-Out” Signaling of Sphingosine-1-Phosphate: Therapeutic Targets (2008) (682)
Sphingosine-1-phosphate links persistent STAT3 activation, chronic intestinal inflammation, and development of colitis-associated cancer. (2013) (466)
Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies. (2019) (385)
Cancer cachexia, mechanism and treatment. (2015) (317)
Targeting SphK1 as a new strategy against cancer. (2008) (293)
Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis. (2012) (262)
Estradiol Induces Export of Sphingosine 1-Phosphate from Breast Cancer Cells via ABCC1 and ABCG2* (2010) (249)
Sustained correction of bleeding disorder in hemophilia B mice by gene therapy. (1999) (231)
Conjugated bile acids activate the sphingosine‐1‐phosphate receptor 2 in primary rodent hepatocytes (2012) (228)
Export and functions of sphingosine-1-phosphate. (2009) (181)
Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential (2016) (146)
Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression (2015) (145)
Export of sphingosine-1-phosphate and cancer progression (2014) (139)
Spns2, a transporter of phosphorylated sphingoid bases, regulates their blood and lymph levels, and the lymphatic network (2013) (137)
Methods of esophagogastric anastomoses following esophagectomy for cancer: A systematic review (2010) (128)
Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion. (2008) (128)
The role of sphingosine 1‐phosphate receptor 2 in bile‐acid–induced cholangiocyte proliferation and cholestasis‐induced liver injury in mice (2017) (124)
Targeting the SphK1/S1P/S1PR1 Axis That Links Obesity, Chronic Inflammation, and Breast Cancer Metastasis. (2018) (119)
Preoperative diagnosis of malignant transformation arising from mature cystic teratoma of the ovary. (2003) (103)
Roles of pathway-specific and inhibitory Smads in activin receptor signaling. (1999) (101)
K63-linked polyubiquitination of transcription factor IRF1 is essential for IL-1-induced production of chemokines CXCL10 and CCL5 (2014) (100)
Cytolytic Activity Score to Assess Anticancer Immunity in Colorectal Cancer (2018) (99)
Tumor Heterogeneity Correlates with Less Immune Response and Worse Survival in Breast Cancer Patients (2019) (96)
CD8 T Cell Score as a Prognostic Biomarker for Triple Negative Breast Cancer (2020) (93)
Primary and secondary angiosarcoma of the breast. (2014) (92)
Resection of the primary tumor improves survival in metastatic breast cancer by reducing overall tumor burden. (2013) (85)
Facial Aesthetic Preferences Among Asian Women: Are All Oriental Asians the Same? (2006) (84)
The phosphorylated prodrug FTY720 is a histone deacetylase inhibitor that reactivates ERα expression and enhances hormonal therapy for breast cancer (2015) (84)
G2M Cell Cycle Pathway Score as a Prognostic Biomarker of Metastasis in Estrogen Receptor (ER)-Positive Breast Cancer (2020) (83)
High expression of ATP-binding cassette transporter ABCC11 in breast tumors is associated with aggressive subtypes and low disease-free survival (2013) (81)
Sphingosine-1-Phosphate Transporters as Targets for Cancer Therapy (2014) (80)
Stress-induced dynamic regulation of mitochondrial STAT3 and its association with cyclophilin D reduce mitochondrial ROS production (2017) (79)
Is tail vein injection a relevant breast cancer lung metastasis model? (2013) (78)
Next generation sequencing‐based gene panel tests for the management of solid tumors (2018) (78)
Sphingosine-1-phosphate in chronic intestinal inflammation and cancer. (2014) (76)
M1 Macrophage and M1/M2 ratio defined by transcriptomic signatures resemble only part of their conventional clinical characteristics in breast cancer (2020) (76)
High levels of sphingolipids in human breast cancer. (2016) (73)
Resolvins and omega three polyunsaturated fatty acids: Clinical implications in inflammatory diseases and cancer. (2016) (70)
Tumor Infiltrating Lymphocytes and Macrophages Improve Survival in Microsatellite Unstable Colorectal Cancer (2019) (70)
Lymphangiogenesis: a new player in cancer progression. (2010) (69)
Triple-Negative Breast Cancer with High Levels of Annexin A1 Expression Is Associated with Mast Cell Infiltration, Inflammation, and Angiogenesis (2019) (69)
Ceramide species are elevated in human breast cancer and are associated with less aggressiveness (2018) (67)
KRAS signaling enriched triple negative breast cancer is associated with favorable tumor immune microenvironment and better survival. (2020) (66)
Hypermutation and microsatellite instability in gastrointestinal cancers (2017) (65)
Overexpression of suppressive microRNAs, miR-30a and miR-200c are associated with improved survival of breast cancer patients (2017) (64)
Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine (2016) (63)
The roles of bile acids and sphingosine-1-phosphate signaling in the hepatobiliary diseases (2016) (63)
The role of sphingosine‐1‐phosphate in inflammation and cancer progression (2018) (63)
Thoracoscopic diagnosis and treatment of chylothorax after pneumonectomy. (1991) (62)
Biologically Aggressive Phenotype and Anti-cancer Immunity Counterbalance in Breast Cancer with High Mutation Rate (2020) (62)
Pancreatic adenocarcinomas with mature blood vessels have better overall survival (2019) (61)
Spinster 2, a sphingosine‐1‐phosphate transporter, plays a critical role in inflammatory and autoimmune diseases (2015) (60)
Emerging Role of Sphingosine-1-phosphate in Inflammation, Cancer, and Lymphangiogenesis (2013) (60)
Current treatment options for colon cancer peritoneal carcinomatosis. (2014) (58)
Abundance of Regulatory T Cell (Treg) as a Predictive Biomarker for Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer (2020) (58)
Actionable gene-based classification toward precision medicine in gastric cancer (2017) (56)
Common driver mutations and smoking history affect tumor mutation burden in lung adenocarcinoma. (2018) (56)
The E2F Pathway Score as a Predictive Biomarker of Response to Neoadjuvant Therapy in ER+/HER2− Breast Cancer (2020) (54)
Estrogen Receptor Positive Breast Cancer with High Expression of Androgen Receptor has Less Cytolytic Activity and Worse Response to Neoadjuvant Chemotherapy but Better Survival (2019) (53)
The role of sphingosine-1-phosphate in breast cancer tumor-induced lymphangiogenesis. (2012) (53)
MYC Targets Scores Are Associated with Cancer Aggressiveness and Poor Survival in ER-Positive Primary and Metastatic Breast Cancer (2020) (51)
Minimum sizes for remnant and transplanted livers in rats (1997) (50)
Angiopoietin pathway gene expression associated with poor breast cancer survival (2017) (49)
Clinical Relevance of microRNA Expressions in Breast Cancer Validated Using the Cancer Genome Atlas (TCGA) (2017) (49)
Breast cancer sphingosine-1-phosphate is associated with phospho-sphingosine kinase 1 and lymphatic metastasis. (2016) (48)
Doxorubicin effect is enhanced by sphingosine-1-phosphate signaling antagonist in breast cancer. (2017) (48)
Plasmacytoid Dendritic Cell (pDC) Infiltration Correlate with Tumor Infiltrating Lymphocytes, Cancer Immunity, and Better Survival in Triple Negative Breast Cancer (TNBC) More Strongly than Conventional Dendritic Cell (cDC) (2020) (47)
Intra-Tumoral Angiogenesis Is Associated with Inflammation, Immune Reaction and Metastatic Recurrence in Breast Cancer (2020) (47)
ABCC1-Exported Sphingosine-1-phosphate, Produced by Sphingosine Kinase 1, Shortens Survival of Mice and Patients with Breast Cancer (2018) (47)
Adenovirus‐mediated overexpression of follistatin enlarges intact liver of adult rats (2003) (45)
Neoadjuvant Chemotherapy for Breast Cancer: Past, Present, and Future (2020) (45)
Immune Cytolytic Activity for Comprehensive Understanding of Immune Landscape in Hepatocellular Carcinoma (2020) (44)
Animal models for exploring the pharmacokinetics of breast cancer therapies (2015) (44)
Metastatic triple-negative breast cancer is dependent on SphKs/S1P signaling for growth and survival. (2017) (44)
Late recurrence of breast cancer is associated with pro-cancerous immune microenvironment in the primary tumor (2019) (44)
A Novel 4-gene Score to Predict Survival, Distant Metastasis and Response to Neoadjuvant Therapy in Breast Cancer (2020) (43)
An improved syngeneic orthotopic murine model of human breast cancer progression (2014) (43)
APOBEC3-Mediated RNA Editing in Breast Cancer is Associated with Heightened Immune Activity and Improved Survival (2019) (42)
Current status and limitations of immunotherapy for breast cancer. (2020) (42)
High expression of bone morphogenetic protein (BMP) 6 and BMP7 are associated with higher immune cell infiltration and better survival in estrogen receptor-positive breast cancer (2019) (40)
Primary and secondary breast angiosarcoma: single center report and a meta-analysis (2019) (39)
Update on the diagnosis and management of malignant phyllodes tumors of the breast. (2017) (38)
Sphingosine‐1‐phosphate phosphatase 2 promotes disruption of mucosal integrity, and contributes to ulcerative colitis in mice and humans (2016) (38)
Anisakidosis: a cause of intestinal obstruction from eating sushi (1998) (38)
Formalin-fixed paraffin-embedded sample conditions for deep next generation sequencing. (2017) (37)
Clinical relevance of tumor microenvironment: immune cells, vessels, and mouse models (2020) (37)
Bevacizumab and breast cancer: what does the future hold? (2012) (37)
Interstitial Fluid Sphingosine-1-Phosphate in Murine Mammary Gland and Cancer and Human Breast Tissue and Cancer Determined by Novel Methods (2016) (36)
High expression of polo-like kinase 1 is associated with TP53 inactivation, DNA repair deficiency, and worse prognosis in ER positive Her2 negative breast cancer. (2019) (36)
Inverted Meckel's diverticulum as a cause of occult lower gastrointestinal hemorrhage. (2012) (36)
High Expression of microRNA-143 is Associated with Favorable Tumor Immune Microenvironment and Better Survival in Estrogen Receptor Positive Breast Cancer (2020) (35)
High Expression of miR-34a Associated with Less Aggressive Cancer Biology but Not with Survival in Breast Cancer (2020) (35)
Lymphovascular invasion in breast cancer is associated with gene expression signatures of cell proliferation but not lymphangiogenesis or immune response (2020) (34)
Tamoxifen sensitivity-related microRNA-342 is a useful biomarker for breast cancer survival (2017) (34)
Clinical Impact of Sphingosine-1-Phosphate in Breast Cancer (2017) (34)
High MYC mRNA Expression Is More Clinically Relevant than MYC DNA Amplification in Triple-Negative Breast Cancer (2019) (34)
High expression of SLCO2B1 is associated with prostate cancer recurrence after radical prostatectomy (2018) (33)
Pyrotinib plus capecitabine for patients with human epidermal growth factor receptor 2-positive breast cancer and brain metastases (PERMEATE): a multicentre, single-arm, two-cohort, phase 2 trial. (2022) (33)
ITPKC as a Prognostic and Predictive Biomarker of Neoadjuvant Chemotherapy for Triple Negative Breast Cancer (2020) (33)
Development of a metastatic murine colon cancer model. (2015) (33)
Intratumoral Adipocyte-High Breast Cancer Enrich for Metastatic and Inflammation-Related Pathways but Associated with Less Cancer Cell Proliferation (2020) (33)
Thymic neoplasm: a rare disease with a complex clinical presentation. (2013) (32)
The evolution of the role of surgery in the management of breast cancer lung metastasis. (2012) (32)
High G2M Pathway Score Pancreatic Cancer is Associated with Worse Survival, Particularly after Margin-Positive (R1 or R2) Resection (2020) (32)
Enhanced DNA Repair Pathway is Associated with Cell Proliferation and Worse Survival in Hepatocellular Carcinoma (HCC) (2021) (32)
Degree of Early Estrogen Response Predict Survival after Endocrine Therapy in Primary and Metastatic ER-Positive Breast Cancer (2020) (31)
DNA damage response and sphingolipid signaling in liver diseases (2016) (31)
Class I histone deacetylase inhibitor suppresses vasculogenic mimicry by enhancing the expression of tumor suppressor and anti-angiogenesis genes in aggressive human TNBC cells (2019) (30)
Breast Tumor Microenvironment in Black Women: A Distinct Signature of CD8+ T Cell Exhaustion. (2021) (30)
Genomic characterization of colitis-associated colorectal cancer (2018) (30)
TP53 is required for BECN1- and ATG5-dependent cell death induced by sphingosine kinase 1 inhibition (2018) (30)
Successful perioperative management of factor X deficiency associated with primary amyloidosis (2004) (30)
SMAD4 alteration associates with invasive‐front pathological markers and poor prognosis in colorectal cancer (2019) (30)
Current Update of Patient-Derived Xenograft Model for Translational Breast Cancer Research (2017) (30)
Clinical and pathological predictors of recurrence in breast cancer patients achieving pathological complete response to neoadjuvant chemotherapy. (2019) (29)
Expression of MicroRNA-9 is Associated With Overall Survival in Breast Cancer Patients. (2019) (29)
Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1‐dependent upregulation of sphingosine kinase 1 transcription (2010) (29)
Novel MicroRNA-Based Risk Score Identified by Integrated Analyses to Predict Metastasis and Poor Prognosis in Breast Cancer (2018) (29)
Host sphingosine kinase 1 worsens pancreatic cancer peritoneal carcinomatosis. (2016) (29)
High expression of Annexin A2 is associated with DNA repair, metabolic alteration, and worse survival in pancreatic ductal adenocarcinoma. (2019) (28)
Molecular Biological Features of Nottingham Histological Grade 3 Breast Cancers (2020) (28)
Dual Scan Mammoscope (DSM)—A New Portable Photoacoustic Breast Imaging System With Scanning in Craniocaudal Plane (2020) (28)
Inflammation Is Associated with Worse Outcome in the Whole Cohort but with Better Outcome in Triple-Negative Subtype of Breast Cancer Patients (2020) (28)
Update on the surgical management of Paget's disease. (2013) (28)
Does removal of the primary tumor in metastatic breast cancer improve survival? (2014) (28)
Intravital microscopy in the study of the tumor microenvironment: from bench to human application (2018) (27)
The role of sphingosine-1-phosphate in the tumor microenvironment and its clinical implications (2017) (27)
Sphingosine-1-Phosphate Facilitates Skin Wound Healing by Increasing Angiogenesis and Inflammatory Cell Recruitment with Less Scar Formation (2019) (26)
Comprehensive genomic sequencing detects important genetic differences between right-sided and left-sided colorectal cancer (2017) (26)
Clinical application of ceramide in cancer treatment (2019) (26)
Transcriptional Repression of SIRT3 Potentiates Mitochondrial Aconitase Activation to Drive Aggressive Prostate Cancer to the Bone (2020) (26)
Contribution of Immune Cells to Glucocorticoid Receptor Expression in Breast Cancer (2020) (26)
Chylothorax after blunt trauma. (2011) (25)
Urine as a Source of Liquid Biopsy for Cancer (2021) (25)
High Expression of NRF2 Is Associated with Increased Tumor-Infiltrating Lymphocytes and Cancer Immunity in ER-Positive/HER2-Negative Breast Cancer (2020) (24)
Advances in the management of peritoneal mesothelioma. (2014) (23)
Sphingosine-1-phosphate in the lymphatic fluid determined by novel methods (2016) (22)
Efficacy of Palbociclib Combinations in Hormone Receptor–Positive Metastatic Breast Cancer Patients After Prior Everolimus Treatment (2018) (22)
Fibroblasts as a Biological Marker for Curative Resection in Pancreatic Ductal Adenocarcinoma (2020) (22)
Impact of Concurrent Genomic Alterations Detected by Comprehensive Genomic Sequencing on Clinical Outcomes in East-Asian Patients with EGFR-Mutated Lung Adenocarcinoma (2018) (22)
Targeting sphingosine-1-phosphate in hematologic malignancies. (2011) (21)
Outcome of Everolimus-Based Therapy in Hormone-Receptor-Positive Metastatic Breast Cancer Patients After Progression on Palbociclib (2020) (21)
Giant peritoneal loose bodies (2006) (21)
Twofer anti-vascular therapy targeting sphingosine-1-phosphate for breast cancer. (2012) (21)
Transcriptomic Profile of Lymphovascular Invasion, a Known Risk Factor of Pancreatic Ductal Adenocarcinoma Metastasis (2020) (20)
Interruption of activin A autocrine regulation by antisense oligodeoxynucleotides accelerates liver tumor cell proliferation. (1999) (20)
Pneumothorax, an underappreciated complication with an airway exchange catheter. (2012) (20)
Bile acids as global regulators of hepatic nutrient metabolism. (2017) (20)
Anisakidosis: a cause of intestinal obstruction from eating sushi. (1998) (19)
Murine model of long-term obstructive jaundice. (2016) (19)
Upregulation of phosphorylated sphingosine kinase 1 expression in colitis-associated cancer. (2018) (19)
Annexin A1 Expression Is Associated with Epithelial–Mesenchymal Transition (EMT), Cell Proliferation, Prognosis, and Drug Response in Pancreatic Cancer (2021) (19)
Management of massive soft tissue defects: The use of INTEGRA® artificial skin after necrotizing soft tissue infection of the chest. (2012) (19)
Novel Breast Cancer Brain Metastasis Patient-Derived Orthotopic Xenograft Model for Preclinical Studies (2020) (19)
Generation of sphingosine-1-phosphate is enhanced in biliary tract cancer patients and is associated with lymphatic metastasis (2018) (19)
Clinical and Genetic Implications of Mutation Burden in Squamous Cell Carcinoma of the Lung (2018) (18)
S1P promotes breast cancer progression by angiogenesis and lymphangiogenesis. (2015) (18)
Low DMT1 Expression Associates With Increased Oxidative Phosphorylation and Early Recurrence in Hepatocellular Carcinoma. (2019) (17)
Different Roles of Sphingosine Kinase 1 and 2 in Pancreatic Cancer Progression. (2018) (17)
Prevalence and clinical relevance of tumor-associated tissue eosinophilia (TATE) in breast cancer. (2020) (17)
Successful treatment of primary pulmonary melanoma. (2011) (17)
Modified breast cancer model for preclinical immunotherapy studies. (2016) (17)
Regulation of hypoxia‐inducible factor functions in the nucleus by sphingosine‐1‐phosphate (2020) (17)
BRAF V600E and SRC mutations as molecular markers for predicting prognosis and conversion surgery in Stage IV colorectal cancer (2019) (16)
Clinical Significance of BRAF Non-V600E Mutations in Colorectal Cancer: A Retrospective Study of Two Institutions. (2018) (16)
A Novel Four-Gene Score to Predict Pathologically Complete (R0) Resection and Survival in Pancreatic Cancer (2020) (16)
Th2 cell infiltrations predict neoadjuvant chemotherapy response of estrogen receptor-positive breast cancer. (2021) (16)
At what age should screening mammography be recommended for Asian women? (2015) (15)
Chemokines, chemokine receptors and the gastrointestinal system. (2013) (15)
Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival (2021) (15)
Pathogenic Germline BRCA1/2 Mutations and Familial Predisposition to Gastric Cancer (2018) (14)
High BRCA2 Gene Expression is Associated with Aggressive and Highly Proliferative Breast Cancer (2021) (14)
Abundance of Microvascular Endothelial Cells Is Associated with Response to Chemotherapy and Prognosis in Colorectal Cancer (2021) (13)
Successful intravenous catheterization by medical students. (2016) (13)
Effect of adenovirus-mediated overexpression of follistatin and extracellular domain of activin receptor type II on gonadotropin secretion in vitro and in vivo. (2002) (13)
Murine breast cancer mastectomy model that predicts patient outcomes for drug development. (2017) (12)
Generating a Murine Orthotopic Metastatic Breast Cancer Model and Performing Murine Radical Mastectomy. (2018) (12)
Orthotopic Implantation Achieves Better Engraftment and Faster Growth Than Subcutaneous Implantation in Breast Cancer Patient-Derived Xenografts (2020) (12)
Benign esophageal schwannoma: a brief overview and our experience with this rare tumor (2017) (12)
K63-linked polyubiquitylation of IRF1 transcription factor is essential for IL-1-induced CCL5 and CXCL10 chemokine production (2014) (12)
Sentinel Lymph Node Biopsy for Breast Cancer: Our Technique and Future Directions in Lymph Node Staging. (2012) (12)
The role of HER-2 in Breast Cancer. (2014) (12)
G2M checkpoint pathway alone is associated with drug response and survival among cell proliferation-related pathways in pancreatic cancer. (2021) (12)
Sphingosine 1-phosphate (S1P) produced by sphingosine kinase 1 (SphK1) and exported via ABCC1 is related to hepatocellular carcinoma (HCC) progression. (2021) (11)
The Impact of Immunofunctional Phenotyping on the Malfunction of the Cancer Immunity Cycle in Breast Cancer (2020) (11)
Angiogenesis is associated with an attenuated tumor microenvironment, aggressive biology, and worse survival in gastric cancer patients. (2021) (10)
Clinical target sequencing for precision medicine of breast cancer (2019) (10)
The Immunosuppressant Fingolimod (FTY720) for the Treatment of Mechanical Force-Induced Abnormal Scars (2020) (10)
Organoids Are Limited in Modeling the Colon Adenoma–Carcinoma Sequence (2021) (10)
A Novel Three-Gene Score as a Predictive Biomarker for Pathologically Complete Response after Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer (2021) (10)
MELK expression in breast cancer is associated with infiltration of immune cell and pathological compete response (pCR) after neoadjuvant chemotherapy. (2021) (10)
A hybrid technique: video-assisted thoracoscopic surgery (VATS) pulmonary resections for community-based surgeons (2010) (10)
Low intratumoral genetic neutrophil-to-lymphocyte ratio (NLR) is associated with favorable tumor immune microenvironment and with survival in triple negative breast cancer (TNBC). (2021) (10)
Enhanced Thermogenesis in Triple-Negative Breast Cancer Is Associated with Pro-Tumor Immune Microenvironment (2021) (10)
Effects of MIR143 on rat sarcoma signaling networks in solid tumors: A brief overview (2020) (10)
Photoacoustic dual-scan mammoscope: results from 38 patients. (2021) (10)
Corrigendum to “Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential” (2016) (9)
Clinical relevance of stem cell surface markers CD133, CD24, and CD44 in colorectal cancer. (2021) (9)
Glucose Drives Growth Factor–Independent Esophageal Cancer Proliferation via Phosphohistidine–Focal Adhesion Kinase Signaling (2019) (9)
Intestinal Co-infection of Tuberculosis and CMV can Cause Massive Lower GI Bleeding in a Patient with HIV. (2013) (9)
Dysregulation of sphingolipid metabolic enzymes leads to high levels of sphingosine‐1‐phosphate and ceramide in human hepatocellular carcinoma (2021) (9)
Outcomes of a hybrid technique for video-assisted thoracoscopic surgery (VATS) pulmonary resection in a community setting. (2011) (9)
A high burden of comorbid conditions leads to decreased survival in breast cancer. (2018) (9)
Breast Cancer in Jamaica: Stage, Grade and Molecular Subtype Distributions Across Age Blocks, the Implications for Screening and Treatment (2021) (9)
Computed tomography (CT) findings of gastric rupture after blunt trauma. (2000) (8)
Increased apoptosis is associated with robust immune cell infiltration and cytolytic activity in breast cancer. (2021) (8)
Operation with less adjuvant therapy for elderly breast cancer. (2016) (8)
A Systematic Approach to Preclinical Trials in Metastatic Breast Cancer (2016) (8)
A cause of unbearably painful breast, diffuse dermal angiomatosis. (2012) (8)
Are video-assisted thoracoscopic surgery (VATS) and robotic video-assisted thoracic surgery (RVATS) for pulmonary resection ready for prime time? (2012) (8)
Direct Delivery of Apatite Nanoparticle-Encapsulated siRNA Targeting TIMP-1 for Intractable Abnormal Scars (2020) (7)
Paradoxical Association of Postoperative Plasma Sphingosine-1-Phosphate with Breast Cancer Aggressiveness and Chemotherapy (2017) (7)
Immune cytolytic activity is associated with reduced intra-tumoral genetic heterogeneity and with better clinical outcomes in triple negative breast cancer. (2021) (7)
Different members of the APOBEC3 family of DNA mutators have opposing associations with the landscape of breast cancer. (2021) (7)
Pseudocirrhosis after chemotherapy in breast cancer, case reports (2018) (7)
Glucose transporter-1 inhibition overcomes imatinib resistance in gastrointestinal stromal tumor cells (2021) (7)
Conformational Modulation of Iduronic Acid-Containing Sulfated Glycosaminoglycans by a Polynuclear Platinum Compound. Implications for Development of Antimetastatic Platinum Drugs. (2020) (7)
A prognostic score based on long-term survivor unique transcriptomic signatures predicts patient survival in pancreatic ductal adenocarcinoma. (2021) (6)
Gastric adenosquamous carcinoma producing granulocyte-colony stimulating factor: a case of a rare malignancy (2017) (6)
ASO Author Reflections: “From Computer to Bedside”: A New Translational Approach to Immunogenomics (2018) (6)
Hernia Sac Laparoscopy under Spinal Anesthesia for Evaluation of Reduced Incarcerated Inguinal Hernia (2007) (6)
Can large B-cell lymphoma mimic cystic lesions of the spleen? (2005) (6)
Low expression of miR-29a is associated with aggressive biology and worse survival in gastric cancer (2021) (6)
Association of Th2 high tumors with aggressive features of breast cancer. (2020) (6)
Transcriptomic and functional pathway features were associated with survival after pathological complete response to neoadjuvant chemotherapy in breast cancer. (2020) (6)
Abundance of reactive oxygen species (ROS) is associated with tumor aggressiveness, immune response, and worse survival in breast cancer (2022) (6)
Sphingosine Kinase 1 is Associated With Immune Cell-Related Gene Expressions in Human Breast Cancer. (2020) (6)
Segmental pericholangial fibrosis: a peculiar benign fibrosing disease at the hepatic hilum. (1997) (5)
The Unfolded Protein Response Is Associated with Cancer Proliferation and Worse Survival in Hepatocellular Carcinoma (2021) (5)
ASO Author Reflections: Transitioning From Morphology to Transcriptomics in Capturing Tumor Biology (2020) (5)
H2A Histone Family Member X (H2AX) Is Upregulated in Ovarian Cancer and Demonstrates Utility as a Prognostic Biomarker in Terms of Overall Survival (2020) (5)
Conflicting roles of EGFR expression by subtypes in breast cancer. (2021) (5)
Extracellular sialyltransferase st6gal1 in breast tumor cell growth and invasiveness (2022) (5)
A novel five-gene score to predict complete pathological response to neoadjuvant chemotherapy in ER-positive/HER2-negative breast cancer. (2021) (5)
Outcomes of Hybrid Video Assisted Thoracoscopic Surgery for Pulmonary Metastasectomy. (2014) (4)
High RAD51 gene expression is associated with aggressive biology and with poor survival in breast cancer (2021) (4)
Minimally Invasive Colostomy Revision for Palliation of Large Stomal Prolapse and an Adherent Sliding Peristomal Hernia (2013) (4)
Cytotoxic T-lymphocyte infiltration and chemokine predict long-term patient survival independently of tumor mutational burden in triple-negative breast cancer (2021) (4)
Exploitation of Sulfated Glycosaminoglycan Status for Precision Medicine of Triplatin in Triple-Negative Breast Cancer (2021) (4)
Scalp Leiomyosarcoma: Diagnosis and Treatment During a Global Pandemic With COVID-19 (2021) (4)
Actionable gene alterations in an Asian population with triple-negative breast cancer. (2018) (4)
Intratumoral density of regulatory T cells is a predictor of host immune response and chemotherapy response in colorectal cancer. (2022) (4)
Octogenarians’ Breast Cancer Is Associated with an Unfavorable Tumor Immune Microenvironment and Worse Disease-Free Survival (2021) (4)
NR2F1, a Tumor Dormancy Marker, Is Expressed Predominantly in Cancer-Associated Fibroblasts and Is Associated with Suppressed Breast Cancer Cell Proliferation (2022) (4)
Altered Expression of Secreted Mediator Genes That Mediate Aggressive Breast Cancer Metastasis to Distant Organs (2020) (4)
Plasma Sphingosine-1-Phosphate Levels Are Associated with Progression of Estrogen Receptor-Positive Breast Cancer (2021) (3)
MIEAP, a p53-downstream gene, is associated with suppression of breast cancer cell proliferation and better survival. (2022) (3)
Should we examine sentinel lymph nodes during the operation? (2012) (3)
The Pathological Response to Anthracycline is Associated with Topoisomerase IIα Gene Amplification in the HER2 Breast Cancer Subset. (2014) (3)
A Presurgical-Window Intervention Trial of Isothiocyanate-Rich Broccoli Sprout Extract in Patients with Breast Cancer. (2022) (3)
Options to Determine Pathological Response of Axillary Lymph Node Metastasis after Neoadjuvant Chemotherapy in Advanced Breast Cancer (2021) (3)
Abstract P1-01-06: Targeting the SphK1/S1P/S1PR1 axis that connects obesity, chronic inflammation, and breast cancer metastasis (2018) (3)
Activin a Receptor Type 2A Mutation Affects the Tumor Biology of Microsatellite Instability-High Gastric Cancer (2021) (3)
Twitter as a survey tool for real-time unbiased snapshots of personal sentiment in population level. (2016) (3)
APOBEC3F expression in triple-negative breast cancer is associated with tumor microenvironment infiltration and activation of cancer immunity and improved survival. (2022) (3)
Intratumoral lymphatic endothelial cell infiltration reflecting lymphangiogenesis is counterbalanced by immune responses and better cancer biology in the breast cancer tumor microenvironment. (2022) (3)
A 10-miRNA risk score-based prediction model for pathological complete response to neoadjuvant chemotherapy in hormone receptor-positive breast cancer (2022) (3)
The Role of the Microbiome on the Pathogenesis and Treatment of Colorectal Cancer (2022) (3)
Outcome of palbociclib based therapy in hormone receptor positive metastatic breast cancer patients after treatment with everolimus. (2017) (3)
Management of Male Breast Cancer: The Journey so Far and Future Directions (2021) (3)
Low RUFY3 expression level is associated with lymph node metastasis in older women with invasive breast cancer (2022) (2)
Development of a novel BRCAness score that predicts response to PARP inhibitors (2022) (2)
Conjugated Bile Acids Accelerate Progression of Pancreatic Cancer Metastasis via S1PR2 Signaling in Cholestasis (2022) (2)
H2AX mRNA expression reflects DNA repair, cell proliferation, metastasis, and worse survival in breast cancer. (2022) (2)
Advances in Oncology in US and Japan: Focusing on Cancer and Infectious Diseases (2021) (2)
Direct and indirect health effects of the nuclear power plant disasters: a review for health care professionals (2022) (2)
Elevated bile acid metabolism and microbiome are associated with suppressed cell proliferation and better survival in breast cancer. (2022) (2)
Systemic Therapy De-Escalation in Early-Stage Triple-Negative Breast Cancer: Dawn of a New Era? (2022) (2)
Racial disparity in breast cancer immune microenvironment. (2018) (2)
Specific inhibitor of sphingosine kinase 1 suppresses tumor-induced angiogenesis and lymphangiogenesis (2011) (2)
Carney's complex in association with right atrial myxoma. (1994) (2)
BRAF V600E and SRC mutations as molecular markers for predicting prognosis and conversion surgery in Stage IV colorectal cancer (2019) (2)
Increased intratumor heterogeneity, angiogenesis and epithelial to mesenchymal transition pathways in metaplastic breast cancer. (2021) (2)
Abstract P2-06-17: A novel interaction of AURKA with MAPK pathway in breast cancer cells as a potential therapeutic target (2019) (2)
Serum semaphorin 4C as a diagnostic biomarker in breast cancer: A multicenter retrospective study (2021) (2)
Sphingosine-1-Phosphate Signaling Targeted Therapy Suppresses Obesity-Related Breast Cancer Progression and Improves Survival (2014) (2)
Abstract P2-09-09: Breast cancer arising on the left side is biologically more aggressive and has worse outcomes compared to the right side (2020) (2)
Outcome of everolimus based therapy in hormone receptor positive metastatic breast cancer patients after progression on palbociclib combination. (2018) (2)
Left sided breast cancer is associated with aggressive biology and worse outcomes than right sided breast cancer (2022) (2)
Gastric cancer with enhanced apical junction pathway has increased metastatic potential and worse clinical outcomes. (2022) (2)
Mutation burden and microsatellite instability in colorectal cancer in Japan and US. (2016) (1)
Abstract PS6-49: Intratumoral cytotoxic t-lymphocyte numbers and chemokine predict long-term survival of triple-negative breast cancer independently of tumor mutational burden (2021) (1)
[A case of lung cancer with mediastinal tumor]. (1990) (1)
Aldehyde Dehydrogenase 1-related Genes in Triple-negative Breast Cancer Investigated Using Network Analysis (2020) (1)
Abstract 4562: Intra-tumor immune activity is linked to genetic diversity of tumor infiltrating lymphocyte and impact clinical outcomes in hepatocellular cancer (2019) (1)
Low DMT1 expression associates with increased oxidative phosphorylation and early recurrence in HCC (2018) (1)
miR-150 expression in breast cancer attracts and activates immune cells, and is associated with better patient outcome. (2022) (1)
A Preclinical Study to Repurpose Spironolactone for Enhancing Chemotherapy Response in Bladder Cancer. (2022) (1)
Is T790M mutation the key in development of resistance to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs)? (2011) (1)
Decreased bile acid metabolism and association with prognosis reflecting microbiome in tumor microenvironment involved in cancer cell proliferation in breast cancer. (2022) (1)
Low expression of miR-195 is associated with cell proliferation, glycolysis and poor survival in estrogen receptor (ER)-positive but not in triple negative breast cancer. (2021) (1)
Abstract P5-03-05: Sphingosine-1-phosphate produced by sphingosine kinase 1 and exported via ABCC1 shortens survival of mice and humans with breast cancer (2018) (1)
Tumor mutation burden in triple negative breast cancer patients in Japan. (2018) (1)
320 Phase IIa study of alpha-DC1 vaccine against HER2/HER3, chemokine modulation regimen and pembrolizumab in patients with asymptomatic brain metastasis from triple negative or HER2+ breast cancer (2020) (1)
E2F cell cycle pathway score as a predictive biomarker of ER+/HER2- breast cancer response to neoadjuvant chemotherapy. (2020) (1)
Association of activin type II receptor mutation with microsatellite instability in gastric cancer. (2017) (1)
The Dimensions of Reports From Around the World That Address Diversity in Oncology (2022) (1)
Abstract 3216: H2AX is a novel prognostic marker of breast cancer (2018) (1)
Earwax type and osmidrosis: prognostic factor for breast cancer? Response to letter to the editor. (2013) (1)
Advanced Stage Is a Risk for Severe Neutropenia in Breast Cancer Patients Undergoing Neoadjuvant Adriamycin/Cyclophosphamide/Docetaxel Chemotherapy (2022) (1)
Do Preys Prey on Their Predators? Confusion over Predatory “Hage-taka” Journals (2019) (1)
Mechano-Sensing Channel PIEZO2 Enhances Invasive Phenotype in Triple-Negative Breast Cancer (2022) (1)
Clinical Relevance of Estrogen Reactivity in the Breast Cancer Microenvironment (2021) (1)
ATP-binding Cassette Transporter ABCC11 is Highly Expressed in Aggressive Breast Cancer Subtypes and Related With Worse Disease-free Survival (2013) (1)
Computed tomography is useful for preoperative workup of gastric rupture caused by blunt trauma (2009) (1)
Behind the clock: elucidating factors contributing to longer clinic appointment duration and patient wait time (2020) (1)
Should we target “intermediate expression” of HER2 in older estrogen receptor positive patients? (2020) (1)
A new photoacoustic breast cancer tomography system that images the patient in standing pose (2020) (1)
Association of NR2F1, a tumor dormancy marker, with cancer cell proliferation and lymph node metastasis, and expression in cancer-associated fibroblasts in breast cancer. (2022) (1)
Elastographic Tomosynthesis From X-Ray Strain Imaging of Breast Cancer (2019) (1)
High miR-99b expression is associated with cell proliferation and worse patient outcomes in breast cancer. (2022) (1)
Development of KAM score to predict metastasis and worse survival in breast cancer. (2021) (1)
Abstract 17: Anti-metastatic platinum through glycan targeting in breast cancer (2017) (1)
Impact of Concurrent Genomic Alterations Detected by Comprehensive Genomic Sequencing on Clinical Outcomes in East-Asian Patients with EGFR-Mutated Lung Adenocarcinoma (2018) (1)
Can Intratumoral neutrophil lymphocyte ratio (NLR) be a prognostic biomarker in breast cancer patients? (2021) (1)
Breast-conserving surgery should not be recommended to men with early-stage breast cancer simply because we can perform these operations. (2016) (1)
ASO Author Reflections: High BRCA2 Gene Expression is Associated with Aggressive and Highly Proliferative Breast Cancer (2021) (1)
De-Escalating the Management of In Situ and Invasive Breast Cancer (2022) (1)
Abstract 5200: High CD73 expression, regulated by estrogen signaling, associates with cancer aggressiveness in estrogen receptor (+) breast cancer (2019) (1)
Abstract IA26: Breast tumor microenvironment in black women: A distinct signature of CD8+ T-cell exhaustion (2020) (1)
Association of allograft rejection response score with biological cancer aggressiveness and with better survival in triple-negative breast cancer (TNBC). (2021) (1)
High CD73 Expression Is Associated with Accelerated Cell Cycle and Cell Adhesion Resulting in Worse Survival in Pancreatic Cancer (2019) (1)
Hypermutation in Breast Cancer: A Potential Marker for Immunotherapy? (2019) (0)
Large panel genomic profiling using CancerPlex to reveal candidates for HER2 targeted therapies in colorectal cancer. (2016) (0)
Abstract P5-05-06: Development of advanced pre-clinical in vivo models of metastatic breast cancer (2018) (0)
Abstract P6-06-06: Immunogenomics approach elucidating clinical significance of DNA repair genes and tumor infiltrating immune cells in breast cancer (2018) (0)
Postoperative Restrictive Opioid Protocols and Durable Changes in Opioid Prescribing and Chronic Opioid Use. (2023) (0)
Biologically Aggressive Phenotype and Anti-cancer Immunity Counterbalance in Breast Cancer with High Mutation Rate (2020) (0)
Intratumoral PDGFB gene predominantly expressed in endothelial cells is associated with angiogenesis and lymphangiogenesis, but not with metastasis in breast cancer (2022) (0)
Axillary lymph node metastasis is one of the most important predictor of outcome in breast cancer (2014) (0)
Esophageal Perforation in a 76-Year-Old Man After C5-C7 Anterior Discectomy and Anterior Plate Fusion (2023) (0)
Development of a New Method to Measure Sphingosine-1-phosphate in Tumor Interstitial Fuid by Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry (2013) (0)
Procancerous immune cells in primary tumor is associated with breast cancer recurrence. (2019) (0)
Abstract P3-08-59: High expression microRNA-143 is associated with favorable tumor immune microenvironment and better survival of ER positive breast cancer patients (2020) (0)
Abstract 6112: Clinical relevance of intra-tumoral density of regulatory T cells as a predictive factor for chemotherapy response in metastatic colorectal cancer (2022) (0)
Association of triple negative breast cancer (TNBC) with high thermogenesis with worse survival and unfavorable tumor microenvironment (TME). (2021) (0)
Correction: ASO Author Reflections: How Does Cholestasis Worsen Pancreatic Cancer Progression? (2023) (0)
Abstract PS16-09: High infiltration of adipocytes is associated with inflammation, metastasis as well as favorable tumor immune microenvironment whereas low infiltration is associated with highly proliferative tumor in ER positive breast cancer patients (2021) (0)
Surgical Stress and Removal of Primary Lesion Influence Breast Cancer Progression, but Survival is Determined by Overall Tumor Burden (2012) (0)
Impact of Environmental Temperature on the Pathological Complete Response and Survival Outcomes of Breast Cancer: A NCDB and SEER study (2023) (0)
High Expression of H2AX Breast Cancer Possesses Higher Radiation Sensitivity and Associated with Early Recurrence (2019) (0)
Abstract P6-06-27: Expression of ATP-binding cassette transporter C1 (ABCC1) and activated sphingosine kinase 1 in breast cancer are associated with significantly shorter disease free survival (2013) (0)
Reply (2016) (0)
Abstract P4-06-05: PanCancer profiling reveals population difference in breast cancer immune microenvironment (2019) (0)
Biomarker Research in World Journal of Oncology (2023) (0)
Immunotherapy: Recent Advances and Its Future as a Neoadjuvant, Adjuvant, and Primary Treatment in Colorectal Cancer (2023) (0)
[Comparative studies on tuberculin activities of tuberculin active peptide (TAP) and its derivatives for human bodies]. (1966) (0)
Defective homologous recombination in platinum based chemotherapy for gastric cancer. (2018) (0)
Types of Cancer and Research Covered in World Journal of Oncology (2022) (0)
Abstract P2-11-28: Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients (2023) (0)
Genomic profiling using a 435-gene panel provides a vision for precision medicine in Japanese gastric cancer. (2017) (0)
Non-Genomic ER-Alpha but Not GPR30 Is Involved in Estradiol-Mediated Release of Sphingosine-1-Phosphate from Breast Cancer (2010) (0)
The Preclinical Development of FTY720, A Sphingosine-1-Phosphate Receptor Modulator, as a Novel Targeting Therapy Against Breast Cancer (2012) (0)
Reversing the resistance to chemotherapy in White and Black patients with triple negative breast cancer (TNBC) (2021) (0)
The Prognostic Value of Stem-Like Markers in Colorectal Cancer (2020) (0)
Pancreatic adenocarcinomas with mature blood vessels have better overall survival (2019) (0)
Tu1820 Sphingosine Kinase 2 Deficiency Disrupts Hepatic Lipid Metabolism (2012) (0)
Abstract P1-01-21: The levels of sphingosine-1-phosphate and its related gene expressions in breast cancer patients (2018) (0)
Clinical Features and Outcomes of Primary Liver Cancer in American Indian/Alaska Natives (2023) (0)
Abstract 112: FTY720-P is a potent inhibitor of class I histone deacetylases that enhances histone acetylation, reactivates ERα expression, and increases hormonal therapeutic sensitivity of breast cancer (2015) (0)
Abstract 2486: APOBEC3B and APOBEC3C-H have opposite associations with DNA instability and immune cell infiltration in breast cancer tumors (2020) (0)
Abstract P5-03-01: Conflicting roles of EGFR expression by subtypes in breast cancer (2022) (0)
Targeting PIM2 by JP11646 results in significant antitumor effects in solid tumors (2022) (0)
Pathological and genetic aggressiveness of left-sided breast cancer. (2019) (0)
Targeting the Sphingosine-1-phosphate Signaling with FTY720 in Obesity Related Breast Cancer Progression (2014) (0)
Abstract P1-07-31: Integrated transcriptomics analyses identify novel three microRNAs signature to predict poor prognosis and metastasis in breast cancer (2018) (0)
Abstract P3-06-16: The pattern of alpha- and beta- adrenergic receptor expression impacts breast cancer outcome (2019) (0)
MicroRNA Signature Predicted Breast Cancer Survival, Bone Metastasis (2017) (0)
Abstract 5653: Increased expression of brain-specific serine/threonine-protein kinase BRSK2 contributes to breast cancer survival by enhancing autophagy under nutrient stress (2022) (0)
CLO22-051: Influence of Environmental Temperature on Pathological Complete Response and Overall Survival in Breast Cancer: A National Cancer Database Population-Based Study (2022) (0)
G2M checkpoint signaling among six-cell proliferation-related pathway as a biomarker for prediction and prognosis in pancreatic cancer. (2021) (0)
Abstract 1049: Orthotopic implantation of aggressive breast cancer achieves better engraftment and larger tumor in patient-derived xenograft models (2018) (0)
ABCC11 (ATP-binding cassette, sub-family C (CFTR/MRP), member 11) (2014) (0)
Abstract 4419: Effect of sphingosine kinase 1 inhibition in validated syngeneic mouse breast cancer metastasis model (2011) (0)
Comparing the American Joint Committee on Cancer (AJCC) breast cancer staging eighth versus seventh edition and breast cancer biology in large databases. (2019) (0)
Abstract 5252: High expression of PLK1, polo-like kinase 1, is significantly associated with DNA repair deficiency, inactivated TP53, and worse prognosis in breast cancer (2019) (0)
Abstract 1694: Conjugated bile acids aggravate metastatic pancreatic cancer via sphingosine-1-phosphate receptor 2 (2016) (0)
The Sphingosine-1-phosphate Receptor Modulator, FTY720, Synergizes With 5-FU to Inhibit Growth of Human Colon Cancer Cells (2013) (0)
Massive Lower Gastrointestinal Bleeding in a Patient Newly Diagnosed with Human Immunodeficiency Virus: 606 (2006) (0)
' s report Title : G betagamma subunits inhibit Epac-induced melanoma cell migration Version : 2 (0)
Abstract 317: Organoid and TIL co-culture system models the human tumor immune microenvironment and drug sensitivity (2020) (0)
Abstract PS4-35: The E2F cell cycle pathway score to predict treatment response among patients with breast cancer (2021) (0)
Abstract P4-02-03: Transcriptomic signature score of Epithelial-Mesenchymal Transition (EMT) of a bulk tumor may not reflect that of cancer cells (2023) (0)
Upregulation of HOX Genes in Pancreatic Ductal Adenocarcinoma Associated with Exceptionally Long Survival (2018) (0)
Abstract P2-05-14: Young breast cancer patients (<40 yo) have unfavorable subtypes, higher stage and worse survival (2018) (0)
Abstract 2518: APOBEC3-mediated C-to-U RNA editing in non-small cell lung cancer tumors is increased in patients with smoking history and squamous tumor histology (2019) (0)
Abstract 5117: Triplatin preferably suppress lung metastasis of breast cancer, and peritoneal carcinomatosis of colon and pancreatic cancer (2017) (0)
Abstract PO022: Metabolic and transcriptional adaptations under hypoxic stress promote breast cancer progression (2021) (0)
A 9-Gene-Based Molecular Prognostic Model Precisely Predicts Survival and Treatment Response in Breast Cancer Patients (2022) (0)
Abstract 5213: Drug repurposing to treat triple negative breast cancer (TNBC) based on a novel ER beta-p53-p73 signaling axis (2020) (0)
Abstract P1-09-09: Octogenerian breast cancer was associated with higher infiltration of M2 macrophages and tregs and worse disease free survival (2019) (0)
Welcome to the Journal of Surgery and Science! (2013) (0)
Abstract P5-05-01: Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive aggressive metastatic breast cancer (2019) (0)
Abstract 404: A novel 4-gene score predict patient survival as well as pathologically complete (R0) resection in pancreatic cancer (2021) (0)
Abstract P5-07-08: Survival relevance of tamoxifen sensitivity-related microRNAs, miR-342 and miR-221/222, in breast cancer patients (2018) (0)
ASO Author Reflections: How Does Cholestasis Worsen Pancreatic Cancer Progression? (2022) (0)
Abstract 4503: Targeting sphingosine kinase 1 is promising novel strategy against breast cancer (2010) (0)
Abstract 1473: Are the genomic gene expression profiles maintained between the original donor and patient-derived xenograft tumors (2015) (0)
Choosing The Right Translational Animal Model Matters: Subcutaneous Versus Orthotopic Implantation Of Mouse Breast Cancer Differentially Expresses Genes Important For Cancer Research And Drug Development (2011) (0)
Genomic landscape of colorectal cancer in Japan: clinical implications of comprehensive genomic sequencing for precision medicine (2016) (0)
Immunogenicity and transcriptomic biology in Nottingham histologic grade 3 breast cancer. (2020) (0)
The combined effect and mechanism of antiangiogenic drugs and PD-L1 inhibitor on cell apoptosis in triple negative breast cancer (2023) (0)
Higher intra-tumoral expression of pro-coagulation genes is a predictor of angiogenesis, epithelial mesenchymal transition and worse patient survival in gastric cancer. (2023) (0)
Abstract 1890: Activated SphK1 and export of S1P via ABCC1 shorten disease free survival in breast cancer (2014) (0)
Functional “Hotness” Score of Cytotoxic T Lymphocyte Infiltration in Tumor Microenvironment Is a Stronger Prognostic Factor of Breast Cancer Patients’ Overall Survival than Cytotoxic T Lymphocyte Infiltration (2018) (0)
Abstract 4887: FTY720 prevent tumorigenesis and suppress the progression of colitis-associated cancer. (2013) (0)
M2 Macrophages, Transforming Growth Factor-β, and ABCC1 Expression as Tumor Promotion Mechanisms in Colorectal Peritoneal Carcinomatosis (2020) (0)
Clostridium difficile Infection Is Associated With Decreased Prostate Cancer Risk: A Retrospective Cohort Study (2023) (0)
Sphingosine-1-Phosphate ( S 1 P ) Stimulation Decreases Vascular Endothelial Growth Factor ( VEGF ) and Interleukin-8 ( IL-8 ) Secretion in Follicular Thyroid Cancer Cell Lines in Vitro (2008) (0)
ASO Visual Abstract: Conjugated Bile Acids Accelerate Progression of Pancreatic Cancer Metastasis via S1PR2 Signaling in Cholestasis (2022) (0)
Abstract 5280: Activation of sphingosine kinase 1 is necessary for angiopoietin 2-induced hemangiogenesis and lymphangiogenesis (2012) (0)
Abstract 4057: Identification of DNA repair genes that affect clonal heterogeneity and the immune microenvironment in breast cancers (2018) (0)
Abstract 3127: Negative impact of paclitaxel on human breast tumor microenvironment and its reversal by the combination of interferon-α with TLR3 agonist rintatolimod (2022) (0)
Abstract PS18-33: Is inflammation a hero or a villain in human breast cancer? (2021) (0)
Abstract 2655: Abundance of intra-tumoral angiogenesis is associated with attenuated tumor aggressive biology, tumor microenvironment, as well as worse survival in gastric cancer patients (2021) (0)
Burnout in the women surgical trainee; is it time to consider a more global approach to tackle this issue? (2023) (0)
Abstract P2-20-12: Abundance of tumor-infiltrating lymphocytes is associated with pathologic complete response to neoadjuvant chemotherapy but not with survival in ER-positive/HER2-negative breast cancer (2023) (0)
Cancer and Inflammation (2016) (0)
Higher CD73 Expression Is Associated with Poor Prognosis in Estrogen Receptor-Positive Breast Cancer (2018) (0)
Abstract 2798: CD73 suppresses anti-cancer immunity and promotes glycolysis, resulting in poor prognosis in pancreatic ductal adenocarcinoma (2021) (0)
Abstract P1-01-04: RUFY3 as a predictive intratumor biomarker for lymph node metastasis in older women with invasive breast cancer (2022) (0)
Abstract PS19-24: Low expression MicroRNA-195 enriched the cell cycle and cell proliferation gene sets and is associated with advanced grades and worse overall survival of ER positive breast cancer patients (2021) (0)
Serum follistatin levels predict the extent of liver regeneration after hepatectomy in human and rat models (2004) (0)
Abstract 120: Local immune cytolytic activity stratifies clinical outcome and is linked to the immune microenvironment in breast cancer (2018) (0)
Tumor Associated Macrophages and TNF-Alpha Production in CT26 Syngeneic Murine Colon Cancer Peritoneal Carcinomatosis can be Suppressed by Inhibition of Sphingosine-1-Phosphate Signaling (2014) (0)
Lack of racial differences in clinical outcomes of breast cancer patients receiving neoadjuvant chemotherapy: a single academic center study (2022) (0)
Meta-analysis of prognostic parameters in primary (PAS) and secondary (SAS) breast angiosarcoma. (2018) (0)
Exploring the lengthiest ambulatory breast surgery clinic appointments: is the patient the problem? (2021) (0)
Targeting Breast Cancer Metastasis Using FTY720 (2012) (0)
Clinical and morphological characterization for detection of hypermutation in colorectal cancer. (2018) (0)
Effect of Sphingosine-1-Phosphate Signaling Disruption in a Murine Synergenic Metastatic Breast Cancer Model (2014) (0)
Establishment of a novel BRCAness score that predicts response to PARP inhibitors. (2022) (0)
Abstract 4103: Sphingosine kinase-1 mediates LPA-induced gastric cancer cell proliferation (2010) (0)
Abstract P5-12-02: Intratumor heterogeneity, angiogenesis and epithelial to mesenchymal transition are enhanced in metaplastic breast cancer (2022) (0)
Decreased Lipid Phosphate Phosphatase 1/3 and Increased Lipid Phosphate Phosphatase 2 Expression in the Human Breast Cancer Tumor Microenvironment Promotes Tumor Progression and Immune System Evasion (2023) (0)
Abstract P3-05-33: High expression of MiR-99b in breast cancer is associated with cell proliferation signaling and worse patient survivals in breast cancer (2023) (0)
Abstract P4-07-29: Reactive Oxygen Species (ROS) pathway is associated with aggressive cancer biology, elevated immune response, and with worse survival in ER-positive/HER2-negative breast cancer (2022) (0)
Abstract A60: AURKA interaction with MEK1/2 complex and its role in promoting breast cancer cell metastasis (2018) (0)
Abstract 2695: FTY720 as a novel therapeutic approach for colon cancer carcinomatosis (2014) (0)
Bromodomain-containing Protein 4 Is a Favourable Prognostic Factor in Breast Cancer Patients (2021) (0)
Abstract 646: The amount of NRF2 expression in bulk tumors involves immune cells as well as cancer cells, which is associated with better prognosis in ER-positive/HER2-negative breast cancer (2021) (0)
Abstract 2697: Prognostic significance of intratumoral neutrophil lymphocyte ratio (NLR) in breast cancer patients (2021) (0)
Inside Out Signaling of Sphingosine-1-Phosphate Promotes Hepatocellular Carcinoma Progression in Humans (2020) (0)
Abstract P3-08-05: High APOBEC3C-H gene expression in tumor associates with better survival in breast cancer (2019) (0)
Oligometastasis scoring system for predicting survival of patients with colorectal liver metastasis after hepatectomy (2021) (0)
Abstract P3-07-07: Functional hotness score of cytotoxic T-lymphocytes infiltration to predicts outcome of triple-negative breast cancer patients (2020) (0)
Serum follistatin level as an early detection marker of post-hepatectomy liver failure: Using our novel rat 90% hepatectomy model (2001) (0)
Abstract 3416: APOBEC3C-H gene expression and APOBEC3-mediated RNA editing in breast cancer tumors are associated with immune response and improved outcome (2019) (0)
Abstract P4-02-28: EMP1 low expressing tumor is associated with cell proliferation and poor overall survival of ER-positive breast cancer patients (2023) (0)
Abstract P2-23-13: Highly proliferative estrogen receptor-positive breast cancer is associated with better response to neoadjuvant chemotherapy but worse clinical outcome (2023) (0)
Abstract 5969: Intra-tumoral coagulation is significantly associated with EMT, angiogenesis, and worse patient survival in gastric cancer (2022) (0)
Abstract 3064: Newer platinum agent, Triplatin NC, is as effective as Triplatin for metastatic breast cancer and pancreatic cancer carcinomatosis (2016) (0)
Tumor Infiltrating Lymphocytes in Luminal A Breast Cancer Is Associated with Cell Proliferation and Worse Survival (2022) (0)
Enhanced immune response outperform aggressive cancer biology and is associated with better survival in triple-negative breast cancer (2022) (0)
Initial patient imaging results from the dual-scan mammoscope system (2021) (0)
Incidence of Breast Cancer and Enterococcus Infection: A Retrospective Analysis (2023) (0)
Estradiol-Induced Sphingosine-1-Phosphate Is Released via ABCC1 and ABCG2, and Activates ERK1/2 (2010) (0)
Abstract 591: Clinical profile and outcome associated with breast cancer recurrence after pathologic complete response to neoadjuvant chemotherapy: A multicenter study (2018) (0)
The Roles of Sphingosine Kinases in Skin Aging. (2019) (0)
Exploitation of sulfated glycosaminoglycan status for precision medicine of platinums in triple-negative breast cancer (2021) (0)
Abstract P2-01-19: Sphingosine-1-phosphate affects tumor-associated macrophages in breast cancer patients (2019) (0)
Abstract 6616: Functional hotness score generated by representative functional cytotoxic T-lymphocytes predicts long-term survival of triple-negative breast cancer independently to the tumor mutational burden (2020) (0)
Abstract P4-07-23: Piezo1 is associated with worse prognosis along with promoted epithelial-mesenchymal transition and hypoxia as well as less anti-cancer immune cells in hormone receptor (HR)-negative breast cancer (2022) (0)
Abstract P2-05-06: Does the lipid mediator sphingosine-1-phosphate have a role in obesity-related cancer progression? (2013) (0)
Abstract 5663: Clinical relevance of unfolded protein response (UPR) signaling in breast cancer (2022) (0)
Human Cytomegalovirus (CMV) Infection Associated With Decreased Risk of Bronchogenic Carcinoma: Understanding How a Previous CMV Infection Leads to an Enhanced Immune Response Against Malignancy (2023) (0)
The Association of Human Cytomegalovirus Infection and Colorectal Cancer: A Clinical Analysis (2023) (0)
Abstract P3-10-01: Mir-150 expression is associated with immune cell infiltration and immune response in breast cancer (2022) (0)
Low Mutant Allele Tumor Heterogeneity Is Associated with Activation of the Intra-Tumor Immune Response and Improved Survival in Colon Cancer (2018) (0)
Improving Gastrointestinal Cancer Care by Enhanced Recovery Protocol Implementation (2023) (0)
Enhanced immune response outperform aggressive cancer biology and is associated with better survival in triple-negative breast cancer (2022) (0)
The Unfolded Protein Response Score Is Associated with Cancer Progression and Survival in Hepatocellular Carcinoma (2021) (0)
Clinical relevance of miR-143 expression in ER-positive breast cancer patients. (2020) (0)
Abstract P2-05-11: Sphingosine-1-phosphate signaling promotes metastatic niches and lung metastasis in obesity-related breast cancer (2016) (0)
Abstract 3941: Heparan sulfate, a new target for platinum in metastatic TNBC (2018) (0)
47982 Reversing the resistance to chemotherapy in White and Black patients with triple negative breast cancer (TNBC). (2021) (0)
Genome-wide Microarray Analysis Demonstrates Significantly Different Tumor Gene Expression Profiles Between Sites of 4T1 Cell Implantation (2012) (0)
Abstract 812: High RAD51 gene expression is associated with aggressive biology and with poor survival in breast cancer (2022) (0)
Abstract 407: FTY720 suppressed CT26 murine colon cancer peritoneal carcinomatosis progression by decreasing tumor associated macrophages and TNF-alpha (2015) (0)
High beta integrin expression is differentially associated with worsened pancreatic ductal adenocarcinoma outcomes. (2022) (0)
Genomic overview of right-sided and left-sided colorectal cancer using comprehensive genomic sequencing. (2017) (0)
Sphingosine-1-phosphate Receptor Modulator, FTY720, Synergizes with 5-fluorouracil and Prolongs Survival in a CT26 Syngeneic Murine Colon Cancer Carcinomatosis Model (2014) (0)
Abstract 475: Resection of primary tumor improves survival in mouse metastatic breast cancer model (2010) (0)
Abstract P6-07-04: Mechanosensing calcium channel PIEZO2 accelerates epithelial-mesenchymal transition in triple-negative breast cancer (2020) (0)
Abstract P1-08-17: Melk expression is associated with immune cell infiltration and pathological compete response (pcr) after neoadjuvant chemotherapy in breast cancer (2022) (0)
Abstract P1-24-05: Breast conserving surgery for non-metastatic inflammatory breast cancer: A National Cancer Database (NCDB) study (2022) (0)
Syringomatous Tumor of the Nipple (2022) (0)
Abstract PS17-51: Angiogenesis in a bulk tumor is associated with cancer immunity and metastasis (2021) (0)
Generation of sphingosine-1-phosphate is enhanced in biliary tract cancer patients and is associated with lymphatic metastasis (2018) (0)
Abstract 3061: Elevated bile acid metabolism is associated with breast cancer microbiome, less cell proliferation, and better survival (2022) (0)
Abstract PD2-10: MiR-150 expression in breast cancer cells attract infiltration of lymphocytes to tumor microenvironment and is associated with better survival of the patients (2023) (0)
Abstract 1601: Clinical studies to treat without surgery for breast cancer cases who achieved clinical complete response by neoadjuvant chemotherapy (2018) (0)
Intraluminal Small Bowel Metastasis From Primary Lung Cancer (2022) (0)
Abstract 5000: Spinster 2 exports S1P, an important player in lymph node metastasis. (2013) (0)
Sphingosine-1-phosphate receptor 2 and conjugated bile acids: Key players in hepatic lipid metabolism. (2015) (0)
107: STAT3 interacts with Cyclophilin D in cancer cells to regulate the mitochondrial permeability transition pore (2014) (0)
4-gene score to predict response to neoadjuvant chemotherapy, metastasis, and survival. (2020) (0)
Comprehensive genomic sequencing for triple negative breast cancer in Japan. (2017) (0)
Abstract 2123: Inhibition of AURKA induces Raf1-independent activation of MAPK pathway in breast cancer cells (2017) (0)
to Promote Gastric Cancer Cell Motility and Invasion Receptors Mediates Up-regulation of Sphingosine Kinase 1 and Epidermal Growth Factor 1 Cross-talk between LPA (2008) (0)
Estradiol Stimulates Export of Sphingosine‐1‐Phosphate From MCF7 Breast Cancer Cells By Specific ABC Transporters (2009) (0)
Leadership Training of Surgery in US. (2017) (0)
Abstract 2072: DNA repair pathway score is associated with cancer aggressiveness and worse survival in hepatocellular carcinoma (HCC) (2021) (0)
Co-Expression of Activated Sphingosine Kinase 1 and ATP-Binding Cassette Transporter C1 (ABCC1) in Breast Cancer is Associated with Significantly Shorter Disease Free Survival (2014) (0)
Appropriateness of Models of Cancer Cell Implantation to Study Breast Cancer Lung Metastasis Evaluated by Genome-Wide Microarray Analysis (2013) (0)
Abstract P3-08-57: A novel gene expression signature score to predict response to neoadjuvant therapy, distant metastasis, and survival in breast cancer (2020) (0)
SLCO2B1 HIGH EXPRESSED TUMOR IN HIGH GLEASON SCORE PROSTATE CANCER PATIENTS RECUR EARLIER AFTER RADICAL PROSTATECTOMY: MP64‐04 (2018) (0)
The Association Between Aspirin and Basal Cell Carcinoma: A Clinical and Financial Analysis (2022) (0)
Abstract P6-11-06: Capecitabine, eribulin and paclitaxel differentially impact the metabolite pool in metastatic breast cancer patients (2023) (0)
Targeting Sphingosine-1-Phosphate Signaling with FTY720 Suppresses Colon Cancer Peritoneal Carcinomatosis Progression in Both CT26 Syngeneic and HCT116 Xenograft Models (2014) (0)
Overexpression of suppressive microRNAs, miR-30a and miR-200c are associated with improved survival of breast cancer patients (2017) (0)
Abstract P1-03-03: Obesity increases the lipid mediator, sphingosine-1-phosphate in the tumor and tumor microenvironment, and promotes tumor progression (2016) (0)
Actionable gene-based classification toward precision medicine in gastric cancer (2017) (0)
Immunoglobulin G4-Negative Inflammatory Pseudotumors of the Pancreas (2021) (0)
Abstract 423: Novel patient-derived orthotopic xenograft model for preclinical studies of breast cancer brain metastasis (2020) (0)
Abstract P1-15-12: Axillary lymph node metastasis and HER2-receptor positivity significantly associate with recurrence and worse survival in breast cancer patients who achieved pathological complete response after neoadjuvant chemotherapy (2019) (0)
Abstract P4-05-16: Immune landscape of glucocorticoid receptor high breast cancer (2020) (0)
Image of the month--quiz case. Heterotopic gastric mucosa. (2008) (0)
Abstract P1-05-06: Establishment of novel BRCA1ness score to quantify BRCAness in breast cancer (2022) (0)
Establishment of Metastatic Breast Cancer Patient-Derived Xenograft (2018) (0)
Low adipocyte hepatocellular carcinoma is associated with aggressive cancer biology and with worse survival. (2022) (0)
[COMPARATIVE STUDIES ON THE REACTIONS OF TUBERCULIN ACTIVE PEPTIDE AND OLD TUBERCULIN RETESTED AT A SITE AFTER A PRIOR REACTION]. (1964) (0)
Abstract P1-01-15: Clinical relevance of TRIM37 gene expression in breast cancer (2022) (0)
Abstract 6426: Novel mechanism of PIM2 inhibition leads to significant effect on solid tumors (2020) (0)
Sphingosine kinase 1 inhibition modulates crosstalk between p53 and autophagic cell death (2017) (0)
Abstract 4884: Determination of sphingosine-1-phosphate levels in tissue interstitial fluid and lymphatic fluid utilizing novel collection techniques (2014) (0)
Abstract P5-07-07: Prognostic relevance of microRNA-155 and microRNA-21 in breast cancer patients (2018) (0)
The clinical relevance of unfolded protein response signaling in breast cancer. (2022) (0)
Novel Score Established by Lung Metastasis Cells Predicts Prognosis and Treatment Response of Breast Cancer Patients (2019) (0)
Abstract 4436: Novel microRNA signature score to predict bone metastasis and prognosis of breast cancer (2017) (0)
FTY720, a Sphingosine-1-phosphate receptor modulator, as a novel targeted therapy against colitis-associated cancer (2014) (0)
An immune-inflamed tumor microenvironment as defined by CD8 score is associated with favorable oncologic outcomes in hepatocellular carcinoma independent of measures of tumor mutational burden. (2022) (0)
Abstract P5-09-03: Intrinsic heterogeneity of triple-negative breast cancer cells triggers vascular mimicry in 3D matrigel matrix environment (2018) (0)
Abstract P3-12-05: Influence of environmental temperature on breast cancer outcomes: A SEER population-based study (2022) (0)
Primary Tumor Resection Decreased the Number of Myeloid Derived Suppressor Cells and Increased CD4 and CD8 Cells (2012) (0)
Abstract P6-03-04: Successful development of patient-derived orthotopic xenograft models of brain and lung metastases of human breast cancer (2019) (0)
Front Cover: Serum semaphorin 4C as a diagnostic biomarker in breast cancer: A multicenter retrospective study (2021) (0)
Abstract 3986: Combination of tamoxifen and doxorubicin targets estrogen receptor beta-mutant p53-p73 axis: A novel therapeutic strategy for triple negative breast cancer (2022) (0)
Abstract LB-325: Sphingosine-1-phosphate links chronic intestinal inflammation to development of colitis-associated cancer. (2013) (0)
Abstract 3280: The sphingosine-1-phosphate receptor modulator FTY720 synergistically inhibits colon cancer cell growth with 5-fluorouracil, irinotecan and oxaliplatin. (2013) (0)
Abstract 31: Favorable impact of higher environmental temperature on clinical outcomes in breast cancer - Does residence matter? A NCDB and SEER population-based study (2022) (0)
Abstract 5827: Increased miR150 expression in tumors enhances lymphocytes infiltration causing immunosuppression through inflammatory chemokines (2022) (0)
ASO Visual Abstract: High BRCA2 Gene Expression is Associated with Aggressive and Highly Proliferative Breast Cancer (2021) (0)
Sphingosine-1- Phosphate(S1P) Export Is Associated with Progression of Hepatocellular Carcinoma(HCC) (2021) (0)
Abstract P4-06-12: Murine radical mastectomy model for preclinical study of adjuvant systemic therapies (2017) (0)
Abstract P5-06-03: Intratumoral lymphatic endothelial cell infiltration reflects lymphangiogenesis and lymph node metastasis, but is counterbalanced by immune response and better cancer biology in breast cancer tumor microenvironment (2022) (0)
Abstract P2-10-03: Detrimental impact of T-regulatory cells on outcome of breast cancer in African American population (2020) (0)
Abstract P3-06-07: Combination of doxorubicin with S1P signaling modulator FTY720 significantly suppressed obesity-associated breast cancer (2017) (0)
Abstract P3-06-15: Young breast cancer patients demonstrate worse survival associated with aggressive oncogene expression but not with mutation load, tumor heterogeneity or pro-tumor immune cell infiltrations (2019) (0)
Abstract P4-04-04: APOBEC3F is expressed by immune cells and is associated with immune response and survival in triple negative breast cancer (2022) (0)
Large-scale genomic sequencing of colorectal cancer in the Japanese population. (2016) (0)
Low expression of microRNA-195 is a poor prognostic marker for ER-positive breast cancer patients. (2021) (0)
Abstract 4364: S1P generated by SphK1 is important not only for primary tumor growth but also for tumor-induced hemangiogenesis and lymphangiogenesis (2012) (0)
Dysregulation of sphingolipid metabolic enzymes leads to high levels of sphingosine‐1‐phosphate and ceramide in human hepatocellular carcinoma (2022) (0)
Abstract 1607: Pro-cancerous immune profile in primary breast tumors affects the timing and type of breast cancer recurrence (2020) (0)
Copy number alteration is an independent prognostic biomarker in triple-negative breast cancer patients. (2023) (0)
Abstract P3-10-04: microRNA-125a high expressing tumors enrich cell proliferation associated gene sets and associated with poor prognosis in estrogen receptor positive breast cancer patients (2022) (0)
Functional hotness score based on three genes predicts long-term survival of triple-negative breast cancer independent from tumor mutational burden. (2020) (0)
Abstract P2-02-04: CD73 expression regulated by estrogen signaling associates with poor prognosis in estrogen receptor (ER)-positive breast cancer (2019) (0)
Abstract 1966: Cell proliferation-related pathway scores (G2M Checkpoint, E2F Targets, MYC Targets V1 and V2, Mitotic Spindle, p53 pathway) as predictive and prognostic biomarkers in pancreatic cancer (2021) (0)

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What Schools Are Affiliated With Kazuaki Takabe?

Kazuaki Takabe is affiliated with the following schools:

Hokkaido University
University at Buffalo
Niigata University
University of Tokyo
Fukushima Medical University
University of Florida
Virginia Commonwealth University
Baylor College of Medicine
Yokohama City University
Osaka University
Tokyo Medical University
Kyoto University