Kazuhide Inoue
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Computer Science
Kazuhide Inoue's Degrees
- PhD Computer Science University of Tokyo
- Masters Computer Science University of Tokyo
- Bachelors Computer Science University of Tokyo
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(Suggest an Edit or Addition)Kazuhide Inoue's Published Works
Number of citations in a given year to any of this author's works
Total number of citations to an author for the works they published in a given year. This highlights publication of the most important work(s) by the author
Published Works
- BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain (2005) (1748)
- P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injury (2003) (1410)
- Neuropathic pain and spinal microglia: a big problem from molecules in ‘small’ glia (2005) (758)
- Neuronal ‘On’ and ‘Off’ signals control microglia (2007) (710)
- UDP acting at P2Y6 receptors is a mediator of microglial phagocytosis (2007) (701)
- Extracellular ATP or ADP Induce Chemotaxis of Cultured Microglia through Gi/o-Coupled P2Y Receptors (2001) (562)
- Activation of p38 mitogen‐activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury (2004) (489)
- Microglia in neuropathic pain: cellular and molecular mechanisms and therapeutic potential (2018) (423)
- Extracellular ATP Triggers Tumor Necrosis Factor‐α Release from Rat Microglia (2000) (406)
- Production and Release of Neuroprotective Tumor Necrosis Factor by P2X7 Receptor-Activated Microglia (2004) (392)
- The function of microglia through purinergic receptors: neuropathic pain and cytokine release. (2006) (322)
- Microglial activation by purines and pyrimidines (2002) (305)
- Involvement of P2X4 and P2Y12 receptors in ATP‐induced microglial chemotaxis (2007) (281)
- Functional vanilloid receptors in cultured normal human epidermal keratinocytes. (2002) (271)
- P2Y12 Receptors in Spinal Microglia Are Required for Neuropathic Pain after Peripheral Nerve Injury (2008) (251)
- Dynamic inhibition of excitatory synaptic transmission by astrocyte-derived ATP in hippocampal cultures (2003) (251)
- JAK-STAT3 pathway regulates spinal astrocyte proliferation and neuropathic pain maintenance in rats. (2011) (247)
- Possible Involvement of P2Y2 Metabotropic Receptors in ATP-Induced Transient Receptor Potential Vanilloid Receptor 1-Mediated Thermal Hypersensitivity (2003) (234)
- IFN-γ receptor signaling mediates spinal microglia activation driving neuropathic pain (2009) (229)
- IRF8 Is a Critical Transcription Factor for Transforming Microglia into a Reactive Phenotype (2012) (226)
- Ca2+ waves in keratinocytes are transmitted to sensory neurons: the involvement of extracellular ATP and P2Y2 receptor activation. (2004) (220)
- Microglial α7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role (2006) (220)
- Selective expression of Gi/o‐coupled ATP receptor P2Y12 in microglia in rat brain (2003) (209)
- Mechanical Allodynia Caused by Intraplantar Injection of P2X Receptor Agonist in Rats: Involvement of Heteromeric P2X2/3 Receptor Signaling in Capsaicin-Insensitive Primary Afferent Neurons (2000) (186)
- Cell type‐specific ATP‐activated responses in rat dorsal root ganglion neurons (1999) (186)
- Mechanisms underlying extracellular ATP‐evoked interleukin‐6 release in mouse microglial cell line, MG‐5 (2001) (180)
- Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays (2009) (174)
- NMDA receptor-independent synaptic plasticity in the central amygdala in the rat model of neuropathic pain (2007) (174)
- P2Y6 receptor‐Gα12/13 signalling in cardiomyocytes triggers pressure overload‐induced cardiac fibrosis (2008) (162)
- Activation of dorsal horn microglia contributes to diabetes‐induced tactile allodynia via extracellular signal‐regulated protein kinase signaling (2008) (160)
- Purinergic receptors in microglia: Functional modal shifts of microglia mediated by P2 and P1 receptors (2013) (155)
- Transcription factor IRF5 drives P2X4R+-reactive microglia gating neuropathic pain (2014) (150)
- Microglia and neuropathic pain (2009) (142)
- Neuronal CCL21 up‐regulates microglia P2X4 expression and initiates neuropathic pain development (2011) (142)
- STAT3-dependent reactive astrogliosis in the spinal dorsal horn underlies chronic itch (2015) (138)
- Pain and purinergic signaling (2010) (132)
- Antidepressants inhibit P2X4 receptor function: a possible involvement in neuropathic pain relief (2009) (131)
- Dorsal horn neurons release extracellular ATP in a VNUT-dependent manner that underlies neuropathic pain (2016) (131)
- P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways (2010) (126)
- P2Y12 receptor‐mediated integrin‐β1 activation regulates microglial process extension induced by ATP (2010) (126)
- Evidence for the involvement of spinal endogenous ATP and P2X receptors in nociceptive responses caused by formalin and capsaicin in mice (1999) (119)
- The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S (2013) (119)
- P2X4 receptors and neuropathic pain (2013) (118)
- ATP stimulation of Ca2+‐dependent plasminogen release from cultured microglia (1998) (116)
- P2Y1 receptor signaling enhances neuroprotection by astrocytes against oxidative stress via IL‐6 release in hippocampal cultures (2009) (111)
- Extracellular adenosine 5′-triphosphate-evoked glutamate release in cultured hippocampal neurons (1992) (111)
- Fibronectin/integrin system is involved in P2X4 receptor upregulation in the spinal cord and neuropathic pain after nerve injury (2008) (111)
- Activation of P2X7 receptors induces CCL3 production in microglial cells through transcription factor NFAT (2009) (110)
- Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex (2018) (110)
- Microglial regulation of neuropathic pain. (2013) (109)
- Microglia and intractable chronic pain (2013) (106)
- The role of nucleotides in the neuron–glia communication responsible for the brain functions (2007) (106)
- ATP facilitates spontaneous glycinergic IPSC frequency at dissociated rat dorsal horn interneuron synapses (2000) (104)
- Lyn tyrosine kinase is required for P2X4 receptor upregulation and neuropathic pain after peripheral nerve injury (2008) (102)
- Blockade of N‐type Ca2+ current by cilnidipine (FRC‐8653) in acutely dissociated rat sympathetic neurones (1997) (101)
- Direct Observation of ATP-Induced Conformational Changes in Single P2X4 Receptors (2009) (100)
- Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction (2017) (98)
- In vivo pathway of thermal hyperalgesia by intrathecal administration of α,β‐methylene ATP in mouse spinal cord: Involvement of the glutamate‐NMDA receptor system (1999) (98)
- A novel P2X4 receptor-selective antagonist produces anti-allodynic effect in a mouse model of herpetic pain (2016) (96)
- Akt activation is involved in P2Y12 receptor‐mediated chemotaxis of microglia (2008) (96)
- Involvement of β1 integrin in microglial chemotaxis and proliferation on fibronectin: Different regulations by ADP through PKA (2005) (93)
- Direct Excitation of Inhibitory Interneurons by Extracellular ATP Mediated by P2Y1 Receptors in the Hippocampal Slice (2004) (92)
- Microglial Ca2+-Activated K+ Channels Are Possible Molecular Targets for the Analgesic Effects of S-Ketamine on Neuropathic Pain (2011) (91)
- Mechanisms Underlying the Neuronal Calcium Sensor-1-evoked Enhancement of Exocytosis in PC12 Cells* (2002) (88)
- Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X4, a key molecule for mechanical allodynia (2006) (86)
- Long‐term potentiation of neuronal excitation by neuron–glia interactions in the rat spinal dorsal horn (2007) (81)
- Astrocytic P2Y1 receptor is involved in the regulation of cytokine/chemokine transcription and cerebral damage in a rat model of cerebral ischemia (2011) (80)
- IMPLICATION OF ATP RECEPTORS IN BRAIN FUNCTIONS (1996) (77)
- CCL2 promotes P2X4 receptor trafficking to the cell surface of microglia (2012) (75)
- Glucocorticoid regulation of ATP release from spinal astrocytes underlies diurnal exacerbation of neuropathic mechanical allodynia (2016) (74)
- Purinergic systems, neuropathic pain and the role of microglia (2012) (73)
- Cytoprotection against oxidative stress‐induced damage of astrocytes by extracellular ATP via P2Y1 receptors (2005) (73)
- Extracellular adenosine 5′-triphosphate-evoked norepinephrine secretion not relating to voltage-gated Ca channels in pheochromocytoma PC12 cells (1989) (72)
- ATP- and adenosine-mediated signaling in the central nervous system: chronic pain and microglia: involvement of the ATP receptor P2X4. (2004) (72)
- Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-Induced Chronic Pain (2012) (72)
- Inhibition by ATP of calcium oscillations in rat cultured hippocampal neurones (1997) (71)
- Neuron–microglia interaction by purinergic signaling in neuropathic pain following neurodegeneration (2016) (71)
- Nerve injury‐activated microglia engulf myelinated axons in a P2Y12 signaling‐dependent manner in the dorsal horn (2010) (70)
- Molecular basis for the dosing time-dependency of anti-allodynic effects of gabapentin in a mouse model of neuropathic pain (2010) (67)
- Adenosine A3 receptor is involved in ADP‐induced microglial process extension and migration (2012) (67)
- Riccardin C: A natural product that functions as a liver X receptor (LXR)α agonist and an LXRβ antagonist (2005) (65)
- Long‐lasting change in brain dynamics induced by methamphetamine: enhancement of protein kinase C‐dependent astrocytic response and behavioral sensitization (2005) (64)
- Purinergic P2Y6 receptors heterodimerize with angiotensin AT1 receptors to promote angiotensin II–induced hypertension (2016) (60)
- Involvement of the chemokine CCL3 and the purinoceptor P2X7 in the spinal cord in paclitaxel-induced mechanical allodynia (2014) (60)
- Identification of intermediates in the bile acid synthetic pathway as ligands for the farnesoid X receptor Published, JLR Papers in Press, May 16, 2004. DOI 10.1194/jlr.M400102-JLR200 (2004) (59)
- Characterization of multiple P2X receptors in cultured normal human epidermal keratinocytes. (2005) (59)
- Thyroid Hormone Targets Matrix Gla Protein Gene Associated With Vascular Smooth Muscle Calcification (2005) (58)
- A new minimally-invasive method for microinjection into the mouse spinal dorsal horn (2015) (58)
- Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K–Akt and MEK–ERK signalling pathways (2009) (57)
- Chemokine (C-C motif) Receptor 5 Is an Important Pathological Regulator in the Development and Maintenance of Neuropathic Pain (2014) (56)
- P2 receptors and chronic pain (2007) (55)
- A Chronic fatigue syndrome model demonstrates mechanical allodynia and muscular hyperalgesia via spinal microglial activation (2014) (54)
- Regulation of cell-to-cell communication mediated by astrocytic ATP in the CNS (2005) (54)
- Potentiation of NMDA receptor-mediated synaptic responses by microglia. (2003) (54)
- BK channels in microglia are required for morphine-induced hyperalgesia (2016) (53)
- Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity (2020) (53)
- Duloxetine Inhibits Microglial P2X4 Receptor Function and Alleviates Neuropathic Pain after Peripheral Nerve Injury (2016) (52)
- Acute hyperglycemia impairs functional improvement after spinal cord injury in mice and humans (2014) (51)
- ATP receptors of microglia involved in pain. (2006) (50)
- GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance (2013) (50)
- Verapamil Increases the Apolipoprotein-Mediated Release of Cellular Cholesterol by Induction of ABCA1 Expression Via Liver X Receptor-Independent Mechanism (2004) (49)
- Spatial and temporal aspects of Ca2+ signaling mediated by P2Y receptors in cultured rat hippocampal astrocytes. (2002) (49)
- Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures (2012) (48)
- Purinergic system, microglia and neuropathic pain. (2012) (48)
- Reduced synaptic activity precedes synaptic stripping in vagal motoneurons after axotomy (2008) (48)
- P2X receptors‐mediated cytosolic phospholipase A2 activation in primary afferent sensory neurons contributes to neuropathic pain (2007) (48)
- Reduced spinal microglial activation and neuropathic pain after nerve injury in mice lacking all three nitric oxide synthases (2011) (48)
- Macrophage centripetal migration drives spontaneous healing process after spinal cord injury (2019) (46)
- Optogenetic Activation of Non-Nociceptive Aβ Fibers Induces Neuropathic Pain-Like Sensory and Emotional Behaviors after Nerve Injury in Rats (2018) (45)
- Signaling of ATP receptors in glia-neuron interaction and pain. (2003) (45)
- Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation Published, JLR Papers in Press, September 16, 2003. DOI 10.1194/jlr.M300215-JLR200 (2004) (44)
- Bone marrow-derived cells in the population of spinal microglia after peripheral nerve injury (2016) (44)
- Role of PAF Receptor in Proinflammatory Cytokine Expression in the Dorsal Root Ganglion and Tactile Allodynia in a Rodent Model of Neuropathic Pain (2010) (43)
- Modification of neuropathic pain sensation through microglial ATP receptors (2007) (43)
- ATP receptors in pain sensation: Involvement of spinal microglia and P2X4 receptors (2005) (42)
- Heterologous down-regulation of angiotensin type 1 receptors by purinergic P2Y2 receptor stimulation through S-nitrosylation of NF-κB (2011) (41)
- Role of endogenous ATP at the incision area in a rat model of postoperative pain (2001) (41)
- P2Y(6)-Evoked Microglial Phagocytosis. (2009) (40)
- Selective and competitive antagonism by suramin of ATP‐stimulated catecholamine‐secretion from PC12 phaeochromocytoma cells (1991) (39)
- Extracellular ATP counteracts the ERK1/2‐mediated death‐promoting signaling cascades in astrocytes (2006) (38)
- The RXR agonists PA024 and HX630 have different abilities to activate LXR/RXR and to induce ABCA1 expression in macrophage cell lines. (2008) (38)
- A spinal microglia population involved in remitting and relapsing neuropathic pain (2022) (38)
- Transcription factor IRF1 is responsible for IRF8-mediated IL-1β expression in reactive microglia. (2015) (37)
- Activation of cytosolic phospholipase A2 in dorsal root ganglion neurons by Ca2+/calmodulin-dependent protein kinase II after peripheral nerve injury (2009) (36)
- Transcription factor MafB contributes to the activation of spinal microglia underlying neuropathic pain development (2018) (36)
- Role of purinergic receptors in CNS function and neuroprotection. (2011) (36)
- ATP- and adenosine-mediated signaling in the central nervous system: synaptic purinoceptors: the stage for ATP to play its "dual-role". (2004) (35)
- ATP Receptor-Operated Ca2+ Influx and Catecholamine Release From Neuronal Cells (1992) (35)
- The novel compounds that activate farnesoid X receptor: the diversity of their effects on gene expression. (2008) (34)
- Role of the P2X4 receptor in neuropathic pain. (2019) (33)
- UDP Facilitates Microglial Phagocytosis Through P2Y6 Receptors (2007) (31)
- Downregulation of P2X3 receptor‐dependent sensory functions in A/J inbred mouse strain (2002) (30)
- IRF8 is a transcriptional determinant for microglial motility (2014) (30)
- Purinergic signaling in microglia in the pathogenesis of neuropathic pain (2017) (30)
- Temporal Kinetics of Microgliosis in the Spinal Dorsal Horn after Peripheral Nerve Injury in Rodents. (2018) (29)
- ATP-activated single-channel currents recorded from cell-free patches of pheochromocytoma PC12 cells (1990) (29)
- Reduced pain behaviors and extracellular signal‐related protein kinase activation in primary sensory neurons by peripheral tissue injury in mice lacking platelet‐activating factor receptor (2007) (29)
- The effect of a secreted form of β‐amyloid‐precursor protein on intracellular Ca2+ increase in rat cultured hippocampal neurones (1998) (29)
- Chronic pain and microglia: the role of ATP. (2004) (29)
- Intrathecal delivery of PDGF produces tactile allodynia through its receptors in spinal microglia (2009) (29)
- Potentiation by adenosine of ATP‐evoked dopamine release via a pertussis toxin‐sensitive mechanism in rat phaeochromocytoma PC12 cells (1994) (29)
- Nociceptive signaling mediated by P2X3, P2X4 and P2X7 receptors. (2020) (28)
- Modulatory effect of plasminogen on NMDA-induced increase in intracellular free calcium concentration in rat cultured hippocampal neurons (1994) (28)
- Enhancement by zinc of ATP-evoked dopamine release from rat pheochromocytoma PC12 cells (1995) (27)
- Platelet-activating factor and pain. (2011) (26)
- Differential modulation of PI3-kinase/Akt pathway during all-trans retinoic acid- and Am80-induced HL-60 cell differentiation revealed by DNA microarray analysis. (2004) (25)
- In vitro farnesoid X receptor ligand sensor assay using surface plasmon resonance and based on ligand-induced coactivator association (2003) (25)
- Clinically potential subclasses of retinoid synergists revealed by gene expression profiling. (2003) (25)
- Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours (2017) (24)
- Inhibitory effects of capsaicin on acetylcholine‐evoked responses in rat phaeochromocytoma cells (1994) (24)
- Adenosine triphosphate accelerates recovery from hypoxic/hypoglycemic perturbation of guinea pig hippocampal neurotransmission via a P2 receptor (2002) (24)
- Activation of GIRK channels in substantia gelatinosa neurones of the adult rat spinal cord: a possible involvement of somatostatin (2008) (23)
- P2Y receptors in microglia and neuroinflammation (2012) (23)
- Selective up-regulation of P2X4-receptor gene expression by interferon-gamma in vascular endothelial cells. (2008) (23)
- Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells (2017) (23)
- Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding (2015) (23)
- Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation (2004) (22)
- Post‐transcriptional downregulation of sarcolipin mRNA by triiodothyronine in the atrial myocardium (2006) (21)
- Effects of ATP antagonists on purinoceptor-operated inward currents in rat phaeochromocytoma cells (1991) (21)
- Interferon regulatory factor 8 expressed in microglia contributes to tactile allodynia induced by repeated cold stress in rodents. (2014) (21)
- Astrocytic STAT3 activation and chronic itch require IP3R1/TRPC-dependent Ca2+ signals in mice. (2020) (20)
- Nociceptive signaling of P2X receptors in chronic pain states (2020) (19)
- P2X4 receptors of microglia in neuropathic pain. (2012) (19)
- Propofol potentiates ATP-activated currents of recombinant P2X4 receptor channels expressed in human embryonic kidney 293 cells (2000) (19)
- ATP induced three types of pain behaviors, including allodynia (2003) (19)
- Characterization of Ca2+ influx through recombinant P2X receptor in C6BU‐1 cells (1998) (18)
- Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome (2019) (18)
- On the Role of ATP-Gated P2X Receptors in Acute, Inflammatory and Neuropathic Pain (2010) (17)
- Inhibition of Ca-channels by diazepam compared with that by nicardipine in pheochromocytoma PC12 cells (1991) (17)
- Riccardin C: a natural product that functions as a liver X receptor (LXR)alpha agonist and an LXRbeta antagonist. (2005) (16)
- A state-of-the-art perspective on microgliopathic pain (2018) (15)
- HX531, a retinoid X receptor antagonist, inhibited the 9-cis retinoic acid-induced binding with steroid receptor coactivator-1 as detected by surface plasmon resonance (2005) (15)
- P2Y12 receptors in primary microglia activate nuclear factor of activated T‐cell signaling to induce C–C chemokine 3 expression (2017) (15)
- Retinoic Acids Increase P2X2 Receptor Expression through the 5′-Flanking Region of P2rx2 Gene in Rat Phaeochromocytoma PC-12 Cells (2006) (14)
- ATP- and acetylcholine-activated channels co-existing in cell-free membrane patches from rat sympathetic neuron (1993) (14)
- Inhibition of G0/G1 Switch 2 Ameliorates Renal Inflammation in Chronic Kidney Disease (2016) (14)
- 5α-Bile alcohols function as farnesoid X receptor antagonists (2006) (14)
- Involvement of protein kinase D in uridine diphosphate‐induced microglial macropinocytosis and phagocytosis (2012) (14)
- Direct excitation of deep dorsal horn neurones in the rat spinal cord by the activation of postsynaptic P2X receptors (2006) (14)
- [The role of microglia and ATP receptors in a mechanism of neuropathic pain]. (2006) (14)
- Adenosine modulates excitatory synaptic transmission and suppresses neuronal death induced by ischaemia in rat spinal motoneurones (2008) (13)
- Effect of extracellular adenosine 5′-triphosphate on principal neurons of the rat ventral tegmental area (1998) (12)
- Contribution of L-type Ca2+ channels to long-term enhancement of high K+-evoked release of dopamine from rat striatal slices (1995) (11)
- Preparation and characterization of a monoclonal antibody against the refolded and functional extracellular domain of rat P2X4 receptor. (2013) (11)
- Role of P2X3 receptors in scratching behavior in mouse models. (2019) (11)
- Neuropharmacological Study of ATP Receptors, Especially in the Relationship between Glia and Pain. (2017) (10)
- ATP reduces voltage-activated K+ current in cultured rat hippocampal neurons (1994) (10)
- Astrocytic Ca2+ responses in the spinal dorsal horn by noxious stimuli to the skin. (2018) (10)
- [Neuropathic pain and ATP receptors in spinal microglia]. (2007) (9)
- Upregulation of P2Y2 receptors by retinoids in normal human epidermal keratinocytes (2006) (9)
- Endothelin-3 activates a voltage-gated Ca channel via a pertussis toxin sensitive mechanism leading to dopamine release from PC12 cells (1994) (9)
- [Role of the glia in neuropathic pain caused by peripheral nerve injury]. (2012) (9)
- Key amino acids of vasopressin V1a receptor responsible for the species difference in the affinity of OPC‐21268 (2000) (9)
- Potentiation by cadmium ion of ATP‐evoked dopamine release in rat phaeochromocytoma cells (1996) (9)
- Block and unblock by imipramine of cloned and mutated P2X2 receptor/channel expressed in Xenopus oocytes (1999) (9)
- [Regulation by astrocytic ATP of synaptic transmission]. (2004) (8)
- Muscarinic acetylcholine recepto r‐mediated increase of angiotensin type 2 receptor mRNA in PC12 cells (1998) (8)
- Involvement of vasodilator-stimulated phosphoprotein in UDP-induced microglial actin aggregation via PKC- and Rho-dependent pathways (2011) (8)
- The Role of ATP Receptors in Pain Signaling (2022) (7)
- P2Y receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database (2019) (7)
- Facilitation by 5-hydroxytryptamine of ATP-activated current in rat pheochromocytoma cells (1994) (7)
- Lentiviral transduction of cultured microglia. (2013) (7)
- (R)- and (S)-4-Amino-3-(trimethylsilyl)methylbutanoic acids ameliorate neuropathic pain without central nervous system-related side effects. (2012) (7)
- Direct Observation of ATP-Induced Conformational Changes in Single P 2 X _ 4 Receptors Shinozaki (7)
- Accentuation by pertussis toxin of the 5-hydroxytryptamine-induced potentiation of ATP-evoked responses in rat pheochromocytoma cells (1995) (7)
- Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure (2019) (6)
- Transcriptional regulation in microglia and neuropathic pain. (2016) (6)
- 5Alpha-bile alcohols function as farnesoid X receptor antagonists. (2006) (6)
- Recent advances in basic neurosciences and brain disease: from synapses to behavior (2006) (6)
- Test of significant differences with a priori probability in microarray experiments. (2003) (6)
- ATP stimulates CA2+-dependent plasminogen release from cultured microglia (1998) (5)
- The Modulation of Synaptic Transmission by the Glial Purinergic System (2010) (5)
- [The mechanism and control of neuropathic pain]. (2009) (5)
- New Inhibitory Effects of Cilnidipine on Microglial P2X7 Receptors and IL-1β Release: An Involvement in its Alleviating Effect on Neuropathic Pain (2021) (5)
- The Role of Microglial Purinergic Receptors in Pain Signaling (2022) (5)
- Block by 5-hydroxytryptamine of neuronal acetylcholine receptor channels expressed inXenopus oocytes (1995) (5)
- Mechanisms underlying facilitation by dopamine of ATP-activated currents in rat pheochromocytoma cells (1993) (5)
- Mechanism of the inhibitory action of ATP in rat hippocampus (2001) (4)
- The extra branch of ARUPS spectra and the atomic structure of the Si(100) surface (1991) (4)
- [Role of molecules expressed in spiral microglia in neuropathic pain]. (2006) (3)
- Relational study of pain: activated microglia and P2X4 in neuropathic pain signaling (2007) (3)
- Independent signaling pathways in ATP‐evoked secretion of plasminogen and cytokines from microglia (2001) (3)
- Cytotoxic effects of methylnitrosourea on developing brain (1983) (3)
- Neurone‐to‐astrocyte communication by endogenous ATP in mixed culture of rat hippocampal neurones and astrocytes (2003) (3)
- Neurochemical and histological analysis of motor dysfunction observed in rats with methylnitrosourea-induced experimental cerebellar hypoplasia (1992) (3)
- [Neuropharmacological study of ATP receptors and their role in neuropathic pain]. (2013) (3)
- Overview for the study of P2 receptors: From P2 receptor history to neuropathic pain studies. (2022) (3)
- Calcium ion modulators : the new wave of psychotropic drugs (1998) (3)
- Chapter 9 P2X Receptors in Sensory Neurons (2006) (2)
- Stability of commercial nifedipine preparations. (1985) (2)
- Effect of adenosine system in the action of oseltamivir on behavior in mice (2015) (2)
- [ATP and neuropathic pain]. (2004) (2)
- Spinal cord is the primary site of action of the cannabinoid CB2 receptor agonist JWH133 that suppresses neuropathic pain: Possible involvement of microglia (2014) (2)
- Neuropathic pain and purinergic receptors: Involvement of microglia (2005) (2)
- [ATP receptors in pain sensation]. (2004) (2)
- Peripheral Nerve Injury: a Mouse Model of Neuropathic Pain. (2017) (2)
- [Involvement of microglia in neuropathic pain signalling]. (2007) (2)
- Community-Pharmacy based Trials for Drug Dose Adjustment in which Pharmacists Evaluate Renal Function (2015) (1)
- [Purinergic regulation of microglia]. (2010) (1)
- Improvement of the affinity of an anti-rat P2X4 receptor antibody by introducing electrostatic interactions (2022) (1)
- Intrathecal infusion of microglia cells. (2013) (1)
- Liposomal clodronate selectively eliminates microglia from primary astrocyte cultures (2012) (1)
- [Role of extracellular nucleotides and their receptors in chronic pain]. (2009) (1)
- Extracellular ATP-stimulated 3H-norepinephrine release coupled with receptor-operated Ca influx in PC12 cells (1990) (1)
- Improvement in reliability of probabilistic test of significant differences in GeneChip experiments. (2004) (1)
- Inhibition of ATP-evoked dopamine release by wortmannin, a myosin light chain kinase inhibitor (1992) (1)
- ATP Receptors in the Pain Signaling: Glial Contribution in Neuropathic Pain (2007) (1)
- Cilnidipine blocks N-type Ca2+ channel in acutely dissociated rat sympathetic neurons (1997) (1)
- P2X4 RECEPTOR ANTAGONIST (2012) (1)
- [Direct imaging of single receptors with fast-scanning atomic force microscopy]. (2009) (1)
- [ATP receptors in pain]. (2006) (1)
- The Research for the Mechanism of Chronically Intractable Pain Based on the Functions of Microglia as Brain Immunocompetent Cell (2016) (1)
- Analysis of damage to Japanese anise-tree, Illicium anisatum L. plantations caused by the camphor tree weevil, Dyscerus hylobioides (Desbrochers) (Coleoptera: Curculionidae) larvae in Shikoku island, southwest Japan (1997) (1)
- Analysis of binding residues in monoclonal antibody with high affinity for the head domain of the rat P2X4 receptor. (2020) (1)
- Overview for the study of P2 Receptors: From P2 Receptor History to Neuropathic Pain Studies (2021) (1)
- Corrigendum to: Key amino acids of vasopressin V1a receptor responsible for the species difference in the affinity of OPC‐21268 (FEBS 23227) (2000) (1)
- Clinical Application and Evaluation of Population Pharmacokinetic Parameters in Phenytoin Dosage Adjustment. (1993) (0)
- Transcription factor MafB contributes to activation of spinal microglia and neuropathic pain after peripheral nerve injury (2019) (0)
- Rapid and selective inhibition of dorsal horn inhibitory interneurons induces morphine-resistant spontaneous nocifensive behaviors (2018) (0)
- Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex (2018) (0)
- Chemogenetic silencing of GABAergic dorsal horn interneurons induces morphine-resistant spontaneous nocifensive behaviours (2017) (0)
- Neuronal CCL21 upregulates microglia P2X4 expression and contributes to neuropathic pain development (2011) (0)
- Improvement of the affinity of an anti-rat P2X4 receptor antibody by introducing electrostatic interactions (2022) (0)
- Novel P2X4 antagonist NP-1719Na-PX reduces allodynia induced by sciatic nerve injury (2013) (0)
- The function of microglial ATP receptors in the expression of allodynia, a specific symptom of neuropathic pain (2006) (0)
- The function of ATP receptors in neuropathic pain :involvment of microglia (2004) (0)
- Activation of ERK1/2 by thyroxine via P13 kinase in H9C2 cells (2002) (0)
- Regulation of microglial function: The association of ATP (1998) (0)
- Tonic and wide-ranging regulation of neurons by gliotrasmitters (2007) (0)
- Fibromyalgia and microglial TNF-α: Translational research using human blood induced microglia-like cells (2017) (0)
- Adenosine 5′-triphosphate mediates synaptic responses causing intracellular calcium increase in hippocampal neurons (1994) (0)
- Functional expression pattern of P2X receptors in rat dorsal root ganglion neurons (1999) (0)
- Quantification of PDGF mRNA and its receptors in mechanically injured rat carotid artery (1994) (0)
- Effects of L-arginine on the systemic, mesenteric, and hepatic circulation of patients with cirrhosis (1998) (0)
- Inhibition by haloperidol of ATP-evoked responses in PCI2 cells (1995) (0)
- Role of spinal microglial cells in pain signaling (2006) (0)
- ATPによる自然”グリオトランスミッションは”培養海馬星状細胞において細胞内シグナリングカスケードのスイッチングオーバーを起こす (2004) (0)
- Development of hexobarbital radiometry and its application (1980) (0)
- BDNF derived from microglia involving neuropathic pain (2006) (0)
- Assessment of P2X4 receptor function in microglial cells using CTP (2010) (0)
- Spinal microglia: A crucial player in pathological chronic pain (2010) (0)
- Effect of humidity on the stability of commercial soft capsule preparations of nifedipine. (1986) (0)
- Hyperactivation of proprioceptors induces microglia-mediated long-lasting pain in a rat model of chronic fatigue syndrome (2019) (0)
- Preparation and clinical evaluation of gentamicin-macrogol-glycerol ointment, with reference to a case of malodorous ulcerated breast cancer (2005) (0)
- Social defeat stress arouse recurrence of pain in ameliorating state (2018) (0)
- Current Topics in the Molecular Mechanisms Underlying Pain (2011) (0)
- The role of STAT3 in the maintenance of neuropathic pain (2010) (0)
- Mechanisms underlying quantal Ca2+ release from ryanodine receptors in PC12 cells (2000) (0)
- Muscarinic acetylcholine receptor-mediated increase in angiotensin type 2 receptor mRNA in PC12 cells: Implication of protein kinase C (1998) (0)
- Effect of P2 receptor antagonist PPADS in a rat model of surgical pain (2000) (0)
- A mechanism of regulation by adenosine of ATP-evoked dopamine release. (1994) (0)
- Microglia activation in neuropathic pain (2010) (0)
- 2S10-4 Touch sensation causes abnormal pain(2S10 Olfaction, Taste and Pain: Sensory Modal Shifts and Brain Mechanisms,The 46th Annual Meeting of the Biophysical Society of Japan) (2008) (0)
- Inhibitory effects ofcapsaicin on acetylcholine-evoked responsesinratphaeochromocytoma cells (1994) (0)
- Biological roles of ATP receptors and microglia: Pharmacologists are essential for drug discovery (2020) (0)
- [Role of IRF transcription factor family in regulating reactive phenotype of microglia]. (2016) (0)
- IN VITRO NEUROTOXICITY ASSAY SYSTEM BY NEURONAL CLONES (1) : EFFECTS OF CHLORDANE ON ELECTROPHYSIOLOGICAL PROPERTIES OF HYBRID NEURONAL CLONE NG 108-15 (1985) (0)
- IRF8 is a transcriptional determinant for microglial motility (2014) (0)
- CCL2 promotes P2X4 receptor trafficking to the cell surface of microglia (2012) (0)
- Ecology and Cultivation of Swertia-plant. VI : A Comparative Study on the Cultivation at the Different Seeding Time at Unzen and Nagasaki (1977) (0)
- Involvement of PKD in UDP-stimulated microglial phagocytosis (2010) (0)
- Pharmacological action of ATP receptors and current status of related drug development (2022) (0)
- Studies on an Establishment of Cells Expressing Human Vasopressin Receptpr and Its Characterlzation. (1998) (0)
- THEORETICAL ANALYSIS OF ARUPS OF A SI(100) SURFACE AT ROOM TEMPERATURE (1991) (0)
- 220 Atp transmits synaptic responses and increases internal calcium in rat cultured hippocampal neurons (1993) (0)
- Characteristic metabolizing pattern of aminopyrine in the fetal liver microsomes of rats (1984) (0)
- Functional coupling of secretion and capacitative Ca2+ entry in neuronal cells. (1999) (0)
- Inhibition by apomorphine and other compounds related to dopamine receptors of neuronal acetylcholine receptor channels expressed in Xenopus oocytes (1995) (0)
- [Neuropathic pain]. (2014) (0)
- Interferon regulatory factor-8 is a transcription factor inducing expression of genes encoding pain-related molecules in spinal microglia (2010) (0)
- Evaluation of 20% Lysozyme Chloride Fine Granules (1984) (0)
- [Regulation of brain function mediated by glial ATP sensors]. (2009) (0)
- Developmental change of activities of drug metabolism in fetal liver microsomes with advancing gestation (1979) (0)
- 3P-0771 Bile acid precursors are endogenous ligands for FXR and mediate the negative feedback regulation of bile acid synthesis (2003) (0)
- Establishment of PC12 cell line stably expressing heteromultimeric complex of P2X2 and P2X3 subtypes (1999) (0)
- Characterisation of elementary Ca2+ release signals in neuronal cells. (1999) (0)
- Capacitative Ca2+ entry in PC12 cells (1998) (0)
- Simultaneous determination of aminopyrine hydroxylation and N-demethylation in liver microsomes by HPLC and effects of inducers on these enzyme reactions (1983) (0)
- Ecology and Cultivation of Swertia-plant. V : Effect of the Low Temperature Treatment at the Different Seeding Time (1977) (0)
- [The role of microglia in neuropathic pain: challenging of eco-pharma]. (2008) (0)
- [Green Pharma: A New Strategy for Drug Discovery in Academia by Targeting Glial Cells and ATP Receptors]. (2018) (0)
- 241 Effect of diltiazem on ATP-induced dopamine release (1997) (0)
- Upregulation of P2X4R expression on surface of fibronectin-stimulated microglia is mediated by CCL2 signaling (2010) (0)
- Dual modulation of ATP-evoked responses by adenosine via GTP-binding proteins in PC12 cells (1994) (0)
- Activation of spinal microglia contributes to paclitaxel-induced mechanical allodynia, cold allodynia and motor dysfunction (2010) (0)
- Differential effect of 3-methylcholanthrene (3-MC) on the drug-metabolizing activities in fetal and maternal livers of rats (1981) (0)
- Evidence for detection of rat P2X4 receptor expressed on cells by generating monoclonal antibodies recognizing the native structure (2019) (0)
- A-1 MECHANISM UNDERLING NEUROTOXICITY OF CHLORDECONE : AN ELECTROPHYSIOLOGICAL APPROACH USING PC12 PHEOCHROMOCYTOMA CELLS (1990) (0)
- The regulation of expression of P2X4 on microglia and very slow modulation of synaptic transmission by P2X4 (2008) (0)
- Real time imaging analysis of microglial condition in acute brain slice (2010) (0)
- Influence of Hemolytic, Chylous and Icteric Factor on Serum Drug Level (1984) (0)
- A study of bradykinin (BK)-evoked dopamine release in rat pheochromocytoma PC12 cells: a potentiation of Ca2+-efficiency in exocytosis via BK-receptor mediated mechanisms. (1994) (0)
- Microglia Secrete Plasminogen Which Enhances the Maturation of Mesencephalic Dopaminergic Neurons in Vitro (1995) (0)
- The structures and functions of ATP receptors (1998) (0)
- Significance of spinal CB2 receptors and their underlying mechanisms in the treatment of neuropathic pain (2010) (0)
- New pharmacological effects of approved drugs targeting P2X7 receptors against the release of IL-1β from microglial cells and neuropathic pain after peripheral nerve injury (2018) (0)
- Evaluation of 20% Lysozyme Chloride Fine Granules : (2) Stability and Compatibility in Solution (1984) (0)
- Microglia causing neuropathic pain after nerve injury (2013) (0)
- Macrophages play a leading role in determining the direction of astrocytic migration in spinal cord injury via ADP-P2Y1R axis (2023) (0)
- The frontline of drug creation for neuropathic pain (2016) (0)
- Involvement of spinal CCL3 in the mechanism of tactile hypersensitization after peripheral nerve injury (2010) (0)
- Comparison of the inductive effect of 3-methylcholanthrene and phénobarbital on the drug-metabolizing enzymes in micro- somes from maternal and fetal liver of rats. (1980) (0)
- Solution structure of rat P2X4 receptor head domain (2015) (0)
- Inhibition by ATP of glutamate release in cultured rat hippocampal neurons (1998) (0)
- A new mechanism for somatosensory information processing by descending noradrenergic pathway via spinal dorsal horn astrocytes (2020) (0)
- B104 cell as a tool for the research of capacitative Ca2+ entry (1998) (0)
- A Novel Algorithm to Test Significant Differences in Microarray Experiments (2002) (0)
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What Schools Are Affiliated With Kazuhide Inoue?
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